Run ID: SRR1166821
Sample name:
Date: 2024-10-05T14:17:27.730212
Number of reads: 1531524
Percentage reads mapped: 77.12
Median coverage: 34.0
Strain: lineage4.1.2.1
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4.1 | Euro-American | None | 0.97 |
lineage4.1.2 | Euro-American | None | 0.97 |
lineage4.1.2.1 | Euro-American (Haarlem) | RD182 | 0.95 |
lineage4 | Euro-American | None | 0.98 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | embB | p.His312Arg | Mutation from literature | |
pyrazinamide | ||||
streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.24 | streptomycin | Uncertain significance | Mutation from literature |
embB | 4247448 | p.His312Arg | missense_variant | 0.3 | ethambutol | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 525 | c.525T>C | synonymous_variant | 0.16 | isoniazid | |
dnaA | 534 | c.534T>G | synonymous_variant | 0.2 | isoniazid | |
dnaA | 540 | c.540C>G | synonymous_variant | 0.21 | isoniazid | |
dnaA | 543 | c.543C>G | synonymous_variant | 0.21 | isoniazid | |
dnaA | 571 | c.571T>C | synonymous_variant | 0.24 | isoniazid | |
dnaA | 576 | c.576G>C | synonymous_variant | 0.23 | isoniazid | |
dnaA | 582 | c.582A>C | synonymous_variant | 0.2 | isoniazid | Not assoc w R - Interim |
dnaA | 591 | c.591C>G | synonymous_variant | 0.18 | isoniazid | |
dnaA | 786 | c.786C>T | synonymous_variant | 0.15 | isoniazid | |
dnaA | 813 | c.813C>T | synonymous_variant | 0.16 | isoniazid | |
dnaA | 1125 | c.1125G>C | synonymous_variant | 0.16 | isoniazid | |
dnaA | 1164 | c.1164A>T | synonymous_variant | 0.15 | isoniazid | |
dnaA | 1177 | p.Ala393Ser | missense_variant | 0.16 | isoniazid | |
dnaA | 1204 | c.1204C>T | synonymous_variant | 0.17 | isoniazid | |
dnaA | 1413 | c.1413A>C | synonymous_variant | 0.15 | isoniazid | |
dnaA | 1416 | c.1416C>G | synonymous_variant | 0.17 | isoniazid | |
dnaA | 1419 | c.1419C>G | synonymous_variant | 0.19 | isoniazid | |
dnaA | 1431 | c.1431A>G | synonymous_variant | 0.24 | isoniazid | |
gyrB | 6133 | c.894G>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6136 | c.897G>A | synonymous_variant | 0.16 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 6148 | c.909C>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6169 | c.930C>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6190 | c.951A>G | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6223 | c.984G>C | synonymous_variant | 0.15 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6295 | c.1056A>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6298 | c.1059C>T | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6299 | c.1060C>T | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 6325 | c.-977C>G | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6361 | c.-941G>A | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6362 | c.-940T>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6379 | c.-923C>G | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6382 | c.-920A>G | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6388 | c.-914T>C | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6400 | c.-902C>G | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6824 | c.1585C>T | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6841 | c.1602T>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6844 | c.-458T>G | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6853 | c.-449A>G | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6856 | c.1617T>C | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6859 | c.1620T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6862 | c.1623C>G | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6878 | c.1639T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6881 | c.1642T>C | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6904 | c.-398C>G | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7523 | c.222C>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7532 | c.231T>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7919 | p.Glu206Asp | missense_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7923 | p.His208Tyr | missense_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8054 | c.753T>C | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8057 | c.756A>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8069 | c.768T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8078 | c.777A>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8090 | c.789C>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8093 | c.792C>G | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8096 | c.795T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8099 | c.798T>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8111 | c.810G>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8225 | c.924T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8253 | p.Ile318Leu | missense_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8283 | p.Ile328Leu | missense_variant | 0.17 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8288 | c.987T>C | synonymous_variant | 0.16 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8391 | p.Tyr364His | missense_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8399 | c.1098T>C | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8420 | c.1119T>C | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8423 | c.1122G>C | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8442 | c.1141C>T | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8453 | c.1152A>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8462 | c.1161A>G | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8471 | c.1170T>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8480 | c.1179C>T | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8786 | c.1485T>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8810 | c.1509A>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8829 | c.1528T>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8852 | c.1551T>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8858 | c.1557T>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8867 | c.1566A>G | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9252 | p.Val651Ile | missense_variant | 0.18 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9275 | c.1974G>A | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9278 | c.1977G>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9281 | c.1980C>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9291 | c.1990C>T | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9311 | c.2010C>T | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9323 | c.2022C>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
fgd1 | 490851 | c.69A>C | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490887 | c.105G>C | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490902 | c.120T>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490905 | c.123T>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490911 | c.129T>G | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490917 | c.135C>A | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490921 | p.Gln47Glu | missense_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490932 | c.150T>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491181 | c.399T>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491191 | p.Gly137Arg | missense_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491259 | c.477T>C | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491286 | c.504G>C | synonymous_variant | 0.38 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491292 | c.510G>C | synonymous_variant | 0.42 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491295 | c.513C>G | synonymous_variant | 0.45 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491296 | p.Val172Ile | missense_variant | 0.48 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491319 | c.537G>C | synonymous_variant | 0.43 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491331 | c.549G>A | synonymous_variant | 0.38 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491532 | c.750G>T | synonymous_variant | 0.29 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 491542 | c.760T>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491547 | c.765A>C | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491550 | c.768T>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491583 | c.801G>A | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491591 | p.Lys270Met | missense_variant | 0.81 | pretomanid | |
delamanid | Uncertain significance | |||||
clofazimine | Not assoc w R | |||||
fgd1 | 491595 | c.813C>G | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491601 | c.819T>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491610 | c.828A>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491616 | c.834A>G | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491620 | p.Ile280Val | missense_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
mshA | 575679 | p.Asn111Ser | missense_variant | 0.93 | isoniazid | Not assoc w R |
ethionamide | Not assoc w R | |||||
mshA | 575734 | c.387T>G | synonymous_variant | 0.3 | isoniazid | |
ethionamide | ||||||
mshA | 575737 | c.390T>C | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
mshA | 575746 | c.399C>G | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
mshA | 575767 | c.420G>A | synonymous_variant | 0.25 | isoniazid | |
ethionamide | ||||||
mshA | 575771 | p.Val142Ser | missense_variant | 0.23 | isoniazid | |
ethionamide | ||||||
mshA | 575779 | c.432A>G | synonymous_variant | 0.31 | isoniazid | |
ethionamide | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.3 | isoniazid | |
ethionamide | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 0.3 | isoniazid | |
ethionamide | ||||||
ccsA | 619591 | c.-300G>C | upstream_gene_variant | 0.25 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619627 | c.-264C>G | upstream_gene_variant | 0.23 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619634 | c.-257T>A | upstream_gene_variant | 0.23 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619648 | c.-243C>G | upstream_gene_variant | 0.2 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619654 | c.-237A>C | upstream_gene_variant | 0.16 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619655 | c.-236A>G | upstream_gene_variant | 0.2 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619669 | c.-222G>C | upstream_gene_variant | 0.21 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619672 | c.-219A>C | upstream_gene_variant | 0.21 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620385 | c.495G>C | synonymous_variant | 0.26 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620388 | c.498A>G | synonymous_variant | 0.3 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620412 | c.522T>C | synonymous_variant | 0.35 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620415 | c.525T>C | synonymous_variant | 0.38 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
ccsA | 620433 | c.543C>G | synonymous_variant | 0.27 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
ccsA | 620436 | c.546T>C | synonymous_variant | 0.24 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620439 | c.549T>C | synonymous_variant | 0.23 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620445 | c.555A>G | synonymous_variant | 0.23 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620661 | c.771C>G | synonymous_variant | 0.15 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620703 | c.813G>C | synonymous_variant | 0.21 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620730 | c.840C>T | synonymous_variant | 0.2 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620733 | c.843G>C | synonymous_variant | 0.18 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620734 | c.844C>A | synonymous_variant | 0.18 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620739 | c.849A>G | synonymous_variant | 0.19 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620745 | c.855G>C | synonymous_variant | 0.18 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620748 | c.858T>A | synonymous_variant | 0.19 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620778 | c.888T>C | synonymous_variant | 0.22 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620784 | c.894C>G | synonymous_variant | 0.22 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620787 | c.897C>G | synonymous_variant | 0.22 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
Rv0565c | 657219 | p.Ala84Val | missense_variant | 0.21 | ethionamide | |
Rv0565c | 657222 | c.249C>G | synonymous_variant | 0.21 | ethionamide | |
Rv0565c | 657231 | p.Ile80Val | missense_variant | 0.2 | ethionamide | |
Rv0565c | 657237 | c.234A>G | synonymous_variant | 0.21 | ethionamide | |
Rv0565c | 657242 | p.Glu77Lys | missense_variant | 0.24 | ethionamide | |
Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 0.26 | ethionamide | |
Rv0565c | 657267 | p.Ser68Pro | missense_variant | 0.25 | ethionamide | Uncertain significance |
Rv0565c | 657291 | c.180C>G | synonymous_variant | 0.22 | ethionamide | |
Rv0565c | 657632 | c.-162G>A | upstream_gene_variant | 0.27 | ethionamide | |
Rv0565c | 657639 | c.-169C>G | upstream_gene_variant | 0.29 | ethionamide | |
Rv0565c | 657641 | c.-171C>G | upstream_gene_variant | 0.29 | ethionamide | |
Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 0.25 | ethionamide | |
Rv0565c | 657678 | c.-209_-208delAAinsGG | upstream_gene_variant | 0.22 | ethionamide | |
Rv0565c | 657686 | c.-216C>G | upstream_gene_variant | 0.21 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAG | upstream_gene_variant | 0.2 | ethionamide | |
Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 0.2 | ethionamide | |
Rv0565c | 657719 | c.-249C>G | upstream_gene_variant | 0.24 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 0.27 | ethionamide | |
hadA | 731792 | c.-138G>A | upstream_gene_variant | 0.15 | isoniazid | |
hadA | 731801 | c.-129C>G | upstream_gene_variant | 0.17 | isoniazid | |
hadA | 731816 | c.-114G>A | upstream_gene_variant | 0.16 | isoniazid | |
hadA | 732272 | p.Ala115Ser | missense_variant | 0.14 | isoniazid | |
hadA | 732295 | c.366G>C | synonymous_variant | 0.23 | isoniazid | |
hadA | 732304 | c.375C>T | synonymous_variant | 0.23 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 0.23 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.23 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.16 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 0.16 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 0.16 | isoniazid | |
hadA | 732346 | c.417T>C | synonymous_variant | 0.18 | isoniazid | |
nusG | 734376 | c.123G>A | synonymous_variant | 0.18 | rifampicin | |
nusG | 734407 | p.Val52Ile | missense_variant | 0.23 | rifampicin | |
nusG | 734421 | c.168A>G | synonymous_variant | 0.21 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 0.21 | rifampicin | |
nusG | 734532 | c.279A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 760101 | c.295T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760106 | c.300G>T | synonymous_variant | 0.18 | rifampicin | |
rpoB | 760112 | c.306T>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 760115 | c.309C>T | synonymous_variant | 0.81 | rifampicin | Not assoc w R |
rpoB | 760118 | c.312T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.19 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.2 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760253 | c.447T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.16 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.14 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.15 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.29 | rifampicin | Uncertain significance |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760418 | c.612G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.32 | rifampicin | Uncertain significance |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243Thr | missense_variant | 0.3 | rifampicin | |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.34 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.37 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 760634 | c.828T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.31 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 760859 | c.1053T>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 760862 | c.1056G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760869 | p.Val355Ile | missense_variant | 0.26 | rifampicin | Uncertain significance |
rpoB | 760886 | c.1080A>G | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760919 | c.1113C>G | synonymous_variant | 0.31 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760934 | c.1128C>T | synonymous_variant | 0.27 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 760970 | c.1164G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761051 | c.1245G>T | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 761054 | c.1248G>A | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761060 | c.1254C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761063 | c.1257C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761097 | c.1291_1292delAGinsTC | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761133 | c.1327_1329delTTGinsCTC | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761168 | c.1362C>G | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761171 | c.1365C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761183 | c.1377T>G | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761189 | c.1383T>G | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761297 | c.1491C>T | synonymous_variant | 0.28 | rifampicin | |
rpoB | 761531 | c.1725C>G | synonymous_variant | 0.19 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.4 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761815 | p.Ala670Glu | missense_variant | 0.2 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761852 | c.2046C>G | synonymous_variant | 0.15 | rifampicin | |
rpoB | 761858 | c.2052G>C | synonymous_variant | 0.15 | rifampicin | |
rpoB | 761864 | c.2058G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761873 | c.2067A>G | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761882 | c.2076C>G | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761891 | c.2085G>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 0.16 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.16 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.17 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.18 | rifampicin | |
rpoB | 761924 | c.2118G>A | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761969 | c.2163G>A | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 761999 | c.2193G>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 762008 | c.2202C>G | synonymous_variant | 0.2 | rifampicin | |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.22 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.19 | rifampicin | Uncertain significance |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 762218 | c.2412T>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 762254 | c.2448T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.22 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 762374 | c.-996G>C | upstream_gene_variant | 0.24 | rifampicin | |
rpoC | 762380 | c.-990T>G | upstream_gene_variant | 0.23 | rifampicin | |
rpoC | 762443 | c.-927G>T | upstream_gene_variant | 0.27 | rifampicin | |
rpoB | 762470 | c.2664G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 762489 | p.Val895Gln | missense_variant | 0.23 | rifampicin | |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763076 | c.-294C>G | upstream_gene_variant | 0.17 | rifampicin | |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 763441 | c.72C>G | synonymous_variant | 0.19 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 763468 | c.99G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 763633 | c.264T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 763642 | c.273G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 763658 | c.289_291delCTTinsTTG | synonymous_variant | 0.31 | rifampicin | |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763708 | c.339G>A | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763709 | c.340C>T | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763714 | c.345G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763735 | c.366G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 763768 | c.399C>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 763780 | c.411C>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763783 | c.414G>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763801 | c.432C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 763819 | c.450G>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 763831 | c.462A>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 0.26 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.26 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.27 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 763945 | c.576T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 763960 | c.591T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 763967 | p.Gly200Ser | missense_variant | 0.17 | rifampicin | |
rpoC | 763978 | c.609C>G | synonymous_variant | 0.16 | rifampicin | |
rpoC | 764024 | c.655T>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764040 | p.Ser224Asn | missense_variant | 0.2 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 764059 | c.690G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764161 | c.792G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Gln | missense_variant | 0.3 | rifampicin | |
rpoC | 764203 | c.834G>T | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764282 | c.913_915delTCGinsAGC | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.18 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036A>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764714 | c.1345C>T | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764720 | c.1351C>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764791 | c.1422C>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R |
rpoC | 764812 | c.1443C>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764824 | c.1455T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764830 | c.1461C>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764893 | c.1524T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.19 | rifampicin | |
rpoC | 764923 | c.1554A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R |
rpoC | 765007 | c.1638T>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 765052 | c.1683C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 765150 | p.Gly594Glu | missense_variant | 1.0 | rifampicin | Not assoc w R |
rpoC | 765451 | c.2082C>G | synonymous_variant | 0.16 | rifampicin | |
rpoC | 765452 | p.Ala695Ser | missense_variant | 0.16 | rifampicin | |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 765493 | c.2124G>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.2 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.2 | rifampicin | |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765979 | c.2610C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 765985 | c.2616C>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.3 | rifampicin | |
rpoC | 766408 | c.3039C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 766444 | c.3075C>G | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766484 | p.Val1039Ile | missense_variant | 0.19 | rifampicin | Uncertain significance |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 766495 | c.3126C>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 766543 | c.3174C>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 766583 | p.Gly1072Ser | missense_variant | 0.41 | rifampicin | |
rpoC | 766591 | c.3222A>G | synonymous_variant | 0.39 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 766597 | c.3228C>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.36 | rifampicin | |
rpoC | 766630 | c.3261G>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766738 | c.3369G>T | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766801 | c.3432C>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>G | synonymous_variant | 0.21 | rifampicin | |
rpoC | 767158 | c.3789T>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 767167 | c.3798C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.3 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 767212 | c.3843G>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 775898 | c.2583G>A | synonymous_variant | 0.19 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775909 | p.Leu858Phe | missense_variant | 0.21 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775916 | c.2565T>G | synonymous_variant | 0.24 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775966 | p.Ala839Ser | missense_variant | 0.18 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775975 | c.2506T>C | synonymous_variant | 0.21 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775981 | p.Leu834Met | missense_variant | 0.22 | bedaquiline | |
clofazimine | ||||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781631 | c.72G>C | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.24 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.26 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.28 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.25 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.27 | streptomycin | |
rpsL | 781751 | c.192G>C | synonymous_variant | 0.24 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.23 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.25 | streptomycin | |
rpsL | 781793 | c.234G>C | synonymous_variant | 0.32 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.38 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.4 | streptomycin | |
rpsL | 781859 | c.300T>C | synonymous_variant | 0.39 | streptomycin | Not assoc w R - Interim |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.34 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.33 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.27 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.27 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.26 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.24 | streptomycin | Uncertain significance |
rplC | 800690 | c.-119C>T | upstream_gene_variant | 0.19 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.22 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.2 | linezolid | |
rplC | 800738 | c.-71T>C | upstream_gene_variant | 0.21 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.2 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.19 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 0.21 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 0.2 | linezolid | |
rplC | 800889 | c.81C>G | synonymous_variant | 0.16 | linezolid | |
rplC | 801127 | p.Ala107Thr | missense_variant | 0.16 | linezolid | |
rplC | 801132 | c.324T>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801174 | c.366T>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801222 | c.414T>C | synonymous_variant | 0.22 | linezolid | |
rplC | 801228 | c.420T>C | synonymous_variant | 0.22 | linezolid | |
rplC | 801246 | c.438C>G | synonymous_variant | 0.3 | linezolid | |
rplC | 801249 | c.441T>G | synonymous_variant | 0.3 | linezolid | |
rplC | 801255 | c.447C>T | synonymous_variant | 0.3 | linezolid | |
fbiC | 1303534 | p.Ser202Ala | missense_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303560 | c.630G>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303584 | c.654C>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303881 | c.951G>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303911 | c.981G>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303920 | c.990C>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303923 | c.993C>T | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303929 | c.999G>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304574 | c.1644C>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304754 | c.1824G>A | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304787 | c.1857T>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304790 | c.1860C>G | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304832 | c.1902C>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
sigE | 1364839 | c.427T>C | synonymous_variant | 0.25 | pyrazinamide | |
sigE | 1364862 | c.450C>G | synonymous_variant | 0.31 | pyrazinamide | |
sigE | 1364865 | c.453G>C | synonymous_variant | 0.33 | pyrazinamide | |
sigE | 1364866 | p.Ala152Ser | missense_variant | 0.3 | pyrazinamide | |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.15 | kanamycin | |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.14 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472044 | n.199G>C | non_coding_transcript_exon_variant | 0.2 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.19 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.23 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.24 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.26 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.26 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.28 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.3 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.3 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.3 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.24 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.29 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.29 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445delCinsTTT | non_coding_transcript_exon_variant | 0.37 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473813 | n.156C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1473839 | n.182G>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>C | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473937 | n.280C>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473945 | n.288T>C | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1473981 | n.324delGinsTT | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1474104 | n.447G>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474111 | n.454T>C | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1474112 | n.455T>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474956 | n.1299C>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1474959 | n.1302C>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1474962 | n.1306delG | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1474970 | n.1313G>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1474991 | n.1334T>C | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1475006 | n.1349A>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1475206 | n.1549C>T | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475209 | n.1552G>C | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475313 | n.1656G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475333 | n.1676T>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>C | non_coding_transcript_exon_variant | 0.37 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475638 | n.1981C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.37 | capreomycin | |
linezolid | ||||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1475763 | n.2106C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.24 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
inhA | 1674507 | c.306G>C | synonymous_variant | 0.25 | isoniazid | |
ethionamide | ||||||
inhA | 1674537 | c.336C>G | synonymous_variant | 0.33 | isoniazid | |
ethionamide | ||||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 0.33 | isoniazid | |
ethionamide | ||||||
inhA | 1674549 | c.348G>C | synonymous_variant | 0.35 | isoniazid | |
ethionamide | ||||||
inhA | 1674555 | c.354G>A | synonymous_variant | 0.35 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674561 | c.360C>T | synonymous_variant | 0.37 | isoniazid | |
ethionamide | ||||||
inhA | 1674582 | c.381T>C | synonymous_variant | 0.32 | isoniazid | |
ethionamide | ||||||
inhA | 1674585 | c.384T>C | synonymous_variant | 0.3 | isoniazid | |
ethionamide | ||||||
inhA | 1674589 | p.Met130Leu | missense_variant | 0.31 | isoniazid | |
ethionamide | ||||||
inhA | 1674624 | c.423A>C | synonymous_variant | 0.33 | isoniazid | |
ethionamide | ||||||
inhA | 1674627 | c.426T>G | synonymous_variant | 0.3 | isoniazid | |
ethionamide | ||||||
inhA | 1674630 | c.429C>G | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1674636 | c.435C>G | synonymous_variant | 0.3 | isoniazid | |
ethionamide | ||||||
inhA | 1674654 | c.453G>C | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 0.25 | isoniazid | |
ethionamide | ||||||
inhA | 1674718 | c.517A>C | synonymous_variant | 0.24 | isoniazid | |
ethionamide | ||||||
inhA | 1674903 | c.702T>C | synonymous_variant | 0.23 | isoniazid | |
ethionamide | ||||||
inhA | 1674904 | p.Ala235Pro | missense_variant | 0.23 | isoniazid | |
ethionamide | ||||||
inhA | 1674909 | c.708G>C | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1674915 | c.714C>G | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674942 | c.741T>C | synonymous_variant | 0.23 | isoniazid | |
ethionamide | ||||||
rpsA | 1833554 | p.Thr5Ala | missense_variant | 0.23 | pyrazinamide | Uncertain significance |
rpsA | 1833568 | c.27G>C | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1833619 | c.78A>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833790 | c.249T>A | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1833799 | c.258C>G | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1833811 | c.270G>C | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1833862 | c.321G>T | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1833970 | c.429G>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834015 | c.474G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834097 | c.556_557delTCinsAG | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834201 | c.660C>T | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834225 | c.684C>G | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834240 | c.699T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834261 | c.720A>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834297 | c.756C>G | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834303 | c.762T>G | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.28 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.31 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834375 | c.834G>A | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834474 | c.933C>G | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834498 | c.957C>T | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834555 | c.1014T>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834558 | c.1017C>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834594 | c.1053C>T | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834606 | c.1065C>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834622 | c.1081_1083delTCGinsAGC | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834666 | c.1125G>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834669 | c.1128G>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834688 | c.1147_1149delAGTinsTCC | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834726 | c.1185C>A | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Pro | missense_variant | 0.15 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834765 | c.1224A>G | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834780 | c.1239A>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834786 | c.1245A>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834789 | c.1248T>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.26 | pyrazinamide | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917934 | c.-6T>C | upstream_gene_variant | 0.87 | capreomycin | |
tlyA | 1917951 | c.12T>C | synonymous_variant | 0.19 | capreomycin | |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
bacA | 2063642 | p.Asp363Tyr | missense_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
ndh | 2101960 | c.1083A>G | synonymous_variant | 0.2 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101966 | c.1077T>G | synonymous_variant | 0.2 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101972 | c.1071G>C | synonymous_variant | 0.2 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
PPE35 | 2170173 | c.437_439dupTGG | conservative_inframe_insertion | 1.0 | pyrazinamide | Uncertain significance |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
kasA | 2517947 | c.-168C>T | upstream_gene_variant | 0.28 | isoniazid | |
kasA | 2517974 | c.-141T>C | upstream_gene_variant | 0.2 | isoniazid | |
kasA | 2517989 | c.-126T>C | upstream_gene_variant | 0.17 | isoniazid | |
kasA | 2517992 | c.-123C>G | upstream_gene_variant | 0.17 | isoniazid | |
kasA | 2518076 | c.-39C>T | upstream_gene_variant | 1.0 | isoniazid | |
kasA | 2518162 | c.48G>A | synonymous_variant | 0.16 | isoniazid | |
kasA | 2518174 | c.60A>G | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518190 | p.Ser26Ala | missense_variant | 0.18 | isoniazid | |
kasA | 2518199 | p.Ile29Val | missense_variant | 0.18 | isoniazid | |
kasA | 2518223 | c.109T>C | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518540 | c.426T>G | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518642 | c.528A>G | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518663 | c.549T>C | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.31 | isoniazid | |
kasA | 2518687 | c.573C>T | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518696 | c.582C>G | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518702 | c.588C>T | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518732 | c.618C>G | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.2 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518792 | c.678C>G | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.36 | isoniazid | |
kasA | 2518816 | c.702C>A | synonymous_variant | 0.37 | isoniazid | |
kasA | 2518822 | c.708C>G | synonymous_variant | 0.36 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.36 | isoniazid | |
kasA | 2518855 | c.741C>G | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518879 | c.765A>G | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518885 | c.771T>C | synonymous_variant | 0.2 | isoniazid | |
ahpC | 2726612 | c.420C>G | synonymous_variant | 0.2 | isoniazid | |
ahpC | 2726638 | p.Ala149Val | missense_variant | 0.23 | isoniazid | |
ahpC | 2726645 | c.453C>G | synonymous_variant | 0.3 | isoniazid | |
ahpC | 2726657 | c.465A>C | synonymous_variant | 0.35 | isoniazid | Not assoc w R - Interim |
ahpC | 2726669 | p.Asp159Glu | missense_variant | 0.3 | isoniazid | |
ahpC | 2726672 | c.480G>A | synonymous_variant | 0.3 | isoniazid | Not assoc w R - Interim |
ahpC | 2726675 | c.483A>G | synonymous_variant | 0.29 | isoniazid | |
ahpC | 2726681 | c.489A>G | synonymous_variant | 0.28 | isoniazid | |
ahpC | 2726687 | c.495C>G | synonymous_variant | 0.26 | isoniazid | |
ahpC | 2726693 | c.501C>G | synonymous_variant | 0.26 | isoniazid | |
ahpC | 2726696 | c.504C>G | synonymous_variant | 0.23 | isoniazid | |
ahpC | 2726735 | c.543C>T | synonymous_variant | 0.14 | isoniazid | |
folC | 2747086 | c.513A>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
folC | 2747089 | c.510G>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
folC | 2747098 | c.501C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
folC | 2747101 | c.498G>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
folC | 2747107 | c.492G>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
folC | 2747110 | c.489T>C | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
folC | 2747113 | c.486C>G | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
folC | 2747116 | c.483G>C | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
folC | 2747302 | c.297A>G | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
folC | 2747314 | c.285A>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
folC | 2747317 | c.282C>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
folC | 2747355 | p.Val82Ile | missense_variant | 0.15 | para-aminosalicylic_acid | |
folC | 2747359 | c.240C>G | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
folC | 2747394 | p.Ile69Val | missense_variant | 0.18 | para-aminosalicylic_acid | |
Rv2477c | 2782483 | c.1560G>C | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782510 | c.1533G>C | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782528 | c.1515G>C | synonymous_variant | 0.3 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782537 | c.1506T>G | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782540 | c.1503T>C | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783062 | c.981C>G | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.28 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783110 | c.933C>A | synonymous_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.33 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783140 | c.903C>G | synonymous_variant | 0.34 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783158 | c.885A>G | synonymous_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783185 | c.858G>C | synonymous_variant | 0.37 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783527 | c.516A>G | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783920 | c.123G>C | synonymous_variant | 0.34 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783953 | c.90G>A | synonymous_variant | 0.44 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783962 | c.81T>C | synonymous_variant | 0.41 | kanamycin | Not assoc w R - Interim |
levofloxacin | ||||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783971 | c.72G>C | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783980 | c.63C>G | synonymous_variant | 0.36 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783992 | c.51T>C | synonymous_variant | 0.33 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2784390 | c.-348G>C | upstream_gene_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784396 | c.-354A>C | upstream_gene_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784405 | c.-363T>C | upstream_gene_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784428 | c.-386T>C | upstream_gene_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784429 | c.-387A>G | upstream_gene_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784432 | c.-390A>C | upstream_gene_variant | 0.29 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784455 | c.-413A>C | upstream_gene_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784456 | c.-414A>C | upstream_gene_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2680 | 2996034 | c.-71G>A | upstream_gene_variant | 0.25 | capreomycin | Uncertain significance |
Rv2752c | 3065687 | p.Gly169Ser | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065901 | c.291A>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065916 | p.Phe92Tyr | missense_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065919 | c.273G>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065925 | p.Ala89Gly | missense_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065928 | c.264G>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065947 | p.Gly82Ala | missense_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065955 | c.235_237delTTGinsCTC | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065979 | c.213T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
thyX | 3067412 | c.534C>G | synonymous_variant | 0.31 | para-aminosalicylic_acid | |
thyX | 3067439 | c.507A>G | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
thyX | 3067451 | c.495G>A | synonymous_variant | 0.31 | para-aminosalicylic_acid | |
thyX | 3067457 | c.489C>G | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067463 | p.Ile161Val | missense_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067466 | c.480G>C | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067470 | p.Asn159Ser | missense_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067619 | c.327A>G | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067640 | c.306G>C | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067643 | c.303C>T | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067652 | c.294T>C | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067661 | c.285C>G | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
thyX | 3067682 | c.264G>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067685 | c.261A>G | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067688 | c.258G>C | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyX | 3067694 | c.252G>C | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067739 | c.207T>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067742 | c.204A>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067799 | c.147G>A | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyX | 3067802 | c.144C>G | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyX | 3067814 | c.132T>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067826 | c.120C>G | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067850 | c.96A>C | synonymous_variant | 0.3 | para-aminosalicylic_acid | |
thyX | 3067869 | p.Thr26Ser | missense_variant | 0.28 | para-aminosalicylic_acid | |
thyX | 3067874 | c.72C>G | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067883 | c.63C>G | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyX | 3067886 | c.60A>C | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067889 | c.57C>G | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067894 | c.52T>C | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyA | 3073827 | c.645A>G | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyA | 3073839 | c.633T>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3073872 | p.Ile200Val | missense_variant | 0.23 | para-aminosalicylic_acid | |
thyA | 3073878 | c.594G>A | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyA | 3073953 | c.519T>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyA | 3073977 | c.495A>G | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyA | 3073989 | c.483T>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyA | 3074001 | c.471C>G | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
thyA | 3074004 | c.468T>C | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
thyA | 3074010 | c.462C>A | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyA | 3074031 | c.441T>C | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
thyA | 3074037 | c.435C>G | synonymous_variant | 0.3 | para-aminosalicylic_acid | |
thyA | 3074056 | p.Glu139Pro | missense_variant | 0.22 | para-aminosalicylic_acid | |
thyA | 3074061 | c.411A>G | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3074076 | c.396C>G | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3074155 | p.Gly106Asp | missense_variant | 0.89 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
lpqB | 3624166 | p.Met249Leu | missense_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624680 | c.231T>G | synonymous_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624686 | p.Glu75Gln | missense_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624701 | c.210T>C | synonymous_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624713 | c.198C>T | synonymous_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625616 | p.Arg333Ala | missense_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625627 | c.-717C>T | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625648 | c.-738T>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625656 | c.958T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625720 | c.894G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625729 | c.885A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625735 | c.879C>A | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625750 | c.864G>A | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.33 | rifampicin | Uncertain significance |
bedaquiline | ||||||
mtrB | 3625762 | c.852A>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625797 | p.Val273Met | missense_variant | 0.4 | rifampicin | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625837 | c.777C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625840 | c.-930A>G | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625852 | c.762A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627227 | c.123T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627242 | c.108C>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627299 | c.-688_-686delTTGinsCTC | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
fbiB | 3642602 | c.1068A>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642605 | c.1071A>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642614 | c.1080C>T | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642620 | c.1086T>C | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642656 | c.1122G>C | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642659 | c.1125C>G | synonymous_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiB | 3642662 | c.1128C>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
rpoA | 3877587 | c.921A>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.33 | rifampicin | |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoA | 3877818 | c.690A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoA | 3877857 | c.651G>A | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3877866 | c.642G>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3877872 | c.636C>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoA | 3877875 | c.633T>G | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3878061 | c.447G>C | synonymous_variant | 0.17 | rifampicin | |
rpoA | 3878067 | c.441C>G | synonymous_variant | 0.16 | rifampicin | |
rpoA | 3878070 | c.438T>C | synonymous_variant | 0.15 | rifampicin | |
rpoA | 3878082 | c.426T>C | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3878094 | c.414C>G | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878100 | c.408C>G | synonymous_variant | 0.26 | rifampicin | |
rpoA | 3878103 | c.405A>G | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3878106 | c.402G>C | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3878118 | c.390T>C | synonymous_variant | 0.26 | rifampicin | |
rpoA | 3878141 | p.Met123Leu | missense_variant | 0.22 | rifampicin | Uncertain significance |
rpoA | 3878142 | p.Gly122Glu | missense_variant | 0.22 | rifampicin | |
rpoA | 3878169 | c.339G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoA | 3878199 | c.309T>C | synonymous_variant | 0.17 | rifampicin | |
rpoA | 3878202 | c.306G>C | synonymous_variant | 0.17 | rifampicin | |
rpoA | 3878217 | c.291A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878220 | c.288C>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoA | 3878271 | c.237T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3878284 | p.Glu75Ala | missense_variant | 0.2 | rifampicin | |
rpoA | 3878292 | c.216T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3878298 | c.210A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3878304 | c.204G>C | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoA | 3878322 | c.186A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoA | 3878331 | c.177A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3878334 | c.174T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3878346 | c.162T>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878364 | c.144A>G | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3878367 | c.141C>G | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3878370 | c.138T>C | synonymous_variant | 0.32 | rifampicin | |
rpoA | 3878376 | c.132G>C | synonymous_variant | 0.33 | rifampicin | |
rpoA | 3878385 | c.123C>G | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878391 | c.117T>C | synonymous_variant | 0.39 | rifampicin | |
rpoA | 3878396 | c.112C>T | synonymous_variant | 0.39 | rifampicin | |
rpoA | 3878436 | c.72A>G | synonymous_variant | 0.51 | rifampicin | |
rpoA | 3878442 | c.66G>C | synonymous_variant | 0.49 | rifampicin | |
rpoA | 3878454 | c.54A>C | synonymous_variant | 0.47 | rifampicin | |
rpoA | 3878472 | p.Asp12Glu | missense_variant | 0.41 | rifampicin | |
rpoA | 3878478 | c.30C>G | synonymous_variant | 0.43 | rifampicin | |
rpoA | 3878490 | c.18C>A | synonymous_variant | 0.39 | rifampicin | |
rpoA | 3878496 | c.12A>T | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3879037 | c.-530G>C | upstream_gene_variant | 0.22 | rifampicin | |
rpoA | 3879040 | c.-533G>C | upstream_gene_variant | 0.22 | rifampicin | |
rpoA | 3879049 | c.-542A>G | upstream_gene_variant | 0.26 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.21 | rifampicin | |
ddn | 3986648 | c.-196C>G | upstream_gene_variant | 0.29 | pretomanid | |
delamanid | ||||||
ddn | 3986655 | c.-189A>T | upstream_gene_variant | 0.27 | pretomanid | |
delamanid | ||||||
ddn | 3986660 | c.-184C>T | upstream_gene_variant | 0.24 | pretomanid | |
delamanid | ||||||
ddn | 3986665 | c.-179G>C | upstream_gene_variant | 0.23 | pretomanid | |
delamanid | ||||||
ddn | 3986667 | c.-177_-176delCTinsAC | upstream_gene_variant | 0.22 | pretomanid | |
delamanid | ||||||
ddn | 3986681 | c.-163C>G | upstream_gene_variant | 0.2 | pretomanid | |
delamanid | ||||||
ddn | 3986690 | c.-154C>G | upstream_gene_variant | 0.16 | pretomanid | |
delamanid | ||||||
clpC1 | 4038271 | p.Pro812Ala | missense_variant | 0.19 | pyrazinamide | |
clpC1 | 4038272 | p.Gly811Ser | missense_variant | 0.19 | pyrazinamide | |
clpC1 | 4038278 | c.2427T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038293 | c.2412G>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4038347 | c.2358G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038356 | c.2349T>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4038359 | c.2346A>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4038368 | c.2337T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038388 | c.2317T>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4038398 | c.2307G>T | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038403 | c.2302T>C | synonymous_variant | 0.18 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038434 | c.2271G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038498 | p.Ser736Thr | missense_variant | 0.2 | pyrazinamide | |
clpC1 | 4038530 | p.Glu725Asp | missense_variant | 0.19 | pyrazinamide | |
clpC1 | 4038536 | c.2169C>T | synonymous_variant | 0.15 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038740 | c.1965G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038755 | c.1950G>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4038790 | c.1915C>T | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4038815 | c.1890G>T | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039073 | c.1632C>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039085 | c.1620A>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039090 | c.1615C>T | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039124 | c.1581C>G | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039127 | c.1578G>A | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.17 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039289 | c.1416T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039295 | c.1410A>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039319 | c.1386T>C | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039322 | c.1383T>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039328 | c.1377A>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039334 | c.1371G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039337 | p.Thr456Gln | missense_variant | 0.17 | pyrazinamide | |
clpC1 | 4039493 | c.1212C>T | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039517 | c.1188C>G | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039524 | p.Phe394Tyr | missense_variant | 0.25 | pyrazinamide | |
clpC1 | 4039586 | c.1119G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039622 | c.1083C>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039682 | c.1023C>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039685 | c.1020C>T | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039748 | c.957G>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039757 | c.948A>G | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4039760 | c.945T>C | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039781 | c.924G>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039787 | c.916_918delTCGinsAGC | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039793 | c.912C>G | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039979 | c.726C>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.32 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4040036 | c.669C>G | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4040093 | c.612C>G | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4040363 | c.342A>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4040369 | c.336C>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040380 | c.325T>C | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4040387 | c.318A>G | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4040393 | c.312G>C | synonymous_variant | 0.23 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040411 | c.294T>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040426 | c.279T>C | synonymous_variant | 0.15 | pyrazinamide | |
panD | 4044188 | c.94T>C | synonymous_variant | 0.19 | pyrazinamide | |
panD | 4044755 | c.-474G>C | upstream_gene_variant | 0.2 | pyrazinamide | |
panD | 4044974 | c.-693C>G | upstream_gene_variant | 0.21 | pyrazinamide | |
panD | 4044977 | c.-696T>C | upstream_gene_variant | 0.22 | pyrazinamide | |
panD | 4044983 | c.-702G>C | upstream_gene_variant | 0.25 | pyrazinamide | |
panD | 4044989 | c.-708T>C | upstream_gene_variant | 0.25 | pyrazinamide | |
panD | 4045000 | c.-719A>C | upstream_gene_variant | 0.29 | pyrazinamide | |
panD | 4045022 | c.-741C>G | upstream_gene_variant | 0.28 | pyrazinamide | |
panD | 4045025 | c.-744C>G | upstream_gene_variant | 0.27 | pyrazinamide | |
panD | 4045028 | c.-747C>G | upstream_gene_variant | 0.26 | pyrazinamide | |
panD | 4045034 | c.-753A>T | upstream_gene_variant | 0.24 | pyrazinamide | |
panD | 4045055 | c.-774T>G | upstream_gene_variant | 0.2 | pyrazinamide | |
glpK | 4138547 | c.1209C>T | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138568 | c.1188A>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138571 | c.1185C>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138583 | c.1173G>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138586 | c.1170C>T | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138594 | p.Asn388Asp | missense_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138606 | c.1150T>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138631 | c.1125C>G | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138634 | c.1122G>T | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138643 | c.1113A>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138664 | c.1092G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138667 | c.1089G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138670 | c.1086G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138679 | p.Met359Val | missense_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138695 | p.Pro354Asp | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138703 | c.1053C>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138706 | c.1050C>G | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138714 | p.Ala348Ser | missense_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138715 | c.1041G>A | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138718 | c.1038T>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138724 | c.1032A>G | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138747 | c.1009C>T | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138751 | c.1005T>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138757 | c.999A>G | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138769 | c.987G>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138772 | p.Ser328Ala | missense_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138781 | c.975G>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139132 | c.622_624delCTAinsTTG | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139135 | c.621T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139143 | c.613T>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139165 | c.591A>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139168 | c.588T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139175 | p.Val194Ala | missense_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139177 | c.579T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139183 | c.573T>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139186 | c.570G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4139575 | p.Val61Ile | missense_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139581 | p.Asn59Asp | missense_variant | 0.29 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
glpK | 4139588 | c.168G>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139597 | c.159C>G | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139630 | c.126C>T | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139651 | p.His35Gln | missense_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
embC | 4239298 | c.-565C>T | upstream_gene_variant | 1.0 | ethambutol | Not assoc w R |
embC | 4240183 | c.321A>G | synonymous_variant | 0.27 | ethambutol | |
embC | 4240600 | c.738G>C | synonymous_variant | 0.17 | ethambutol | |
embC | 4240671 | p.Thr270Ile | missense_variant | 0.21 | ethambutol | Not assoc w R |
embC | 4240678 | c.816T>G | synonymous_variant | 0.26 | ethambutol | |
embC | 4240685 | p.Thr275Ala | missense_variant | 0.26 | ethambutol | |
embC | 4240693 | c.831T>C | synonymous_variant | 0.22 | ethambutol | |
embC | 4240706 | p.Val282Thr | missense_variant | 0.21 | ethambutol | |
embC | 4240726 | c.864G>C | synonymous_variant | 0.26 | ethambutol | Not assoc w R - Interim |
embC | 4240780 | c.918T>C | synonymous_variant | 0.29 | ethambutol | |
embC | 4240783 | c.921G>C | synonymous_variant | 0.28 | ethambutol | |
embC | 4240789 | c.927T>C | synonymous_variant | 0.31 | ethambutol | |
embC | 4240819 | c.957A>G | synonymous_variant | 0.27 | ethambutol | |
embC | 4240831 | c.969T>G | synonymous_variant | 0.24 | ethambutol | |
embC | 4240867 | c.1005T>G | synonymous_variant | 0.32 | ethambutol | |
embC | 4240870 | c.1008T>C | synonymous_variant | 0.31 | ethambutol | |
embC | 4240897 | c.1035C>G | synonymous_variant | 0.24 | ethambutol | Not assoc w R |
embC | 4240900 | c.1038A>G | synonymous_variant | 0.24 | ethambutol | |
embC | 4240936 | c.1074A>G | synonymous_variant | 0.28 | ethambutol | |
embC | 4240945 | c.1083T>C | synonymous_variant | 0.2 | ethambutol | |
embC | 4240954 | p.Ile364Met | missense_variant | 0.17 | ethambutol | |
embC | 4240957 | c.1095C>G | synonymous_variant | 0.17 | ethambutol | |
embC | 4240966 | c.1104G>T | synonymous_variant | 0.19 | ethambutol | Not assoc w R - Interim |
embC | 4240996 | c.1134G>C | synonymous_variant | 0.19 | ethambutol | |
embC | 4241017 | c.1155T>C | synonymous_variant | 0.22 | ethambutol | |
embC | 4241023 | c.1161T>G | synonymous_variant | 0.22 | ethambutol | |
embC | 4241026 | c.1164C>G | synonymous_variant | 0.19 | ethambutol | |
embC | 4241035 | c.1173G>A | synonymous_variant | 0.26 | ethambutol | |
embC | 4241050 | c.1188T>G | synonymous_variant | 0.3 | ethambutol | |
embC | 4241104 | c.1242G>A | synonymous_variant | 0.33 | ethambutol | Not assoc w R - Interim |
embC | 4241107 | c.1245G>C | synonymous_variant | 0.37 | ethambutol | |
embC | 4241137 | c.1275G>C | synonymous_variant | 0.26 | ethambutol | |
embC | 4241140 | c.1278A>G | synonymous_variant | 0.25 | ethambutol | Not assoc w R - Interim |
embC | 4241141 | p.Ile427Val | missense_variant | 0.24 | ethambutol | Uncertain significance |
embC | 4241158 | c.1296T>C | synonymous_variant | 0.24 | ethambutol | |
embC | 4241161 | c.1299C>G | synonymous_variant | 0.24 | ethambutol | Not assoc w R - Interim |
embC | 4241162 | c.1300T>C | synonymous_variant | 0.24 | ethambutol | |
embC | 4241453 | p.Ile531Val | missense_variant | 0.22 | ethambutol | |
embC | 4241473 | c.1611G>A | synonymous_variant | 0.16 | ethambutol | |
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embC | 4242803 | p.Val981Leu | missense_variant | 0.97 | ethambutol | Not assoc w R |
embA | 4245077 | c.1845G>C | synonymous_variant | 0.19 | ethambutol | |
embA | 4245083 | c.1851A>C | synonymous_variant | 0.18 | ethambutol | |
embA | 4245089 | c.1857G>C | synonymous_variant | 0.21 | ethambutol | |
embA | 4245092 | c.1860C>G | synonymous_variant | 0.24 | ethambutol | |
embA | 4245101 | c.1869G>C | synonymous_variant | 0.25 | ethambutol | |
embA | 4245137 | c.1905T>C | synonymous_variant | 0.19 | ethambutol | |
embA | 4245149 | c.1917C>G | synonymous_variant | 0.24 | ethambutol | |
embA | 4245182 | c.1950T>C | synonymous_variant | 0.23 | ethambutol | |
embA | 4245194 | c.1962G>C | synonymous_variant | 0.2 | ethambutol | |
embA | 4245198 | p.Leu656Ile | missense_variant | 0.18 | ethambutol | |
embA | 4245206 | c.1974A>G | synonymous_variant | 0.17 | ethambutol | |
embA | 4245207 | c.1975T>C | synonymous_variant | 0.17 | ethambutol | |
embA | 4245215 | c.1983A>G | synonymous_variant | 0.21 | ethambutol | |
embA | 4245222 | p.Tyr664Gln | missense_variant | 0.2 | ethambutol | |
embB | 4245740 | c.-774T>C | upstream_gene_variant | 0.19 | ethambutol | |
embB | 4245764 | c.-750G>C | upstream_gene_variant | 0.23 | ethambutol | |
embA | 4245771 | p.Asn847Ser | missense_variant | 0.24 | ethambutol | Uncertain significance |
embB | 4246355 | c.-159G>C | upstream_gene_variant | 0.17 | ethambutol | |
embA | 4246359 | p.Ala1043Pro | missense_variant | 0.17 | ethambutol | |
embB | 4246367 | c.-147C>T | upstream_gene_variant | 0.16 | ethambutol | |
embB | 4246373 | c.-141T>C | upstream_gene_variant | 0.16 | ethambutol | |
embB | 4246376 | c.-138G>C | upstream_gene_variant | 0.16 | ethambutol | |
embB | 4247358 | p.Val282Ala | missense_variant | 0.17 | ethambutol | Uncertain significance |
embB | 4247365 | c.852A>C | synonymous_variant | 0.19 | ethambutol | |
embB | 4247371 | c.858C>G | synonymous_variant | 0.23 | ethambutol | |
embB | 4247375 | p.Leu288Val | missense_variant | 0.24 | ethambutol | |
embB | 4247386 | c.873T>C | synonymous_variant | 0.26 | ethambutol | |
embB | 4247389 | c.876C>G | synonymous_variant | 0.26 | ethambutol | |
embB | 4247395 | c.882C>G | synonymous_variant | 0.25 | ethambutol | |
embB | 4247401 | c.888T>C | synonymous_variant | 0.24 | ethambutol | |
embB | 4247437 | c.924A>G | synonymous_variant | 0.27 | ethambutol | Not assoc w R - Interim |
embB | 4247440 | c.927C>G | synonymous_variant | 0.27 | ethambutol | |
embB | 4247464 | c.951C>G | synonymous_variant | 0.26 | ethambutol | |
embB | 4247470 | c.957T>C | synonymous_variant | 0.24 | ethambutol | |
embB | 4247491 | c.978G>C | synonymous_variant | 0.24 | ethambutol | |
embB | 4247500 | c.987C>G | synonymous_variant | 0.24 | ethambutol | |
embB | 4247800 | c.1287A>C | synonymous_variant | 0.24 | ethambutol | |
embB | 4247806 | c.1293G>C | synonymous_variant | 0.23 | ethambutol | |
embB | 4247819 | p.Val436Ile | missense_variant | 0.28 | ethambutol | Uncertain significance |
embB | 4247824 | c.1311C>G | synonymous_variant | 0.27 | ethambutol | |
embB | 4247830 | c.1317A>C | synonymous_variant | 0.25 | ethambutol | |
embB | 4247836 | c.1323A>G | synonymous_variant | 0.25 | ethambutol | Not assoc w R - Interim |
embB | 4247842 | c.1329T>C | synonymous_variant | 0.27 | ethambutol | |
embB | 4247876 | c.1363C>T | synonymous_variant | 0.21 | ethambutol | |
embB | 4247881 | c.1368G>C | synonymous_variant | 0.21 | ethambutol | |
embB | 4248142 | c.1629T>C | synonymous_variant | 0.16 | ethambutol | |
embB | 4248157 | c.1644A>G | synonymous_variant | 0.19 | ethambutol | Not assoc w R - Interim |
embB | 4248206 | p.Ser565Gly | missense_variant | 0.2 | ethambutol | Uncertain significance |
embB | 4248220 | c.1707A>G | synonymous_variant | 0.19 | ethambutol | Not assoc w R - Interim |
embB | 4248241 | c.1728C>T | synonymous_variant | 0.17 | ethambutol | |
embB | 4248265 | c.1752C>T | synonymous_variant | 0.17 | ethambutol | |
embB | 4248266 | c.1753C>T | synonymous_variant | 0.16 | ethambutol | |
aftB | 4269201 | c.-365A>G | upstream_gene_variant | 0.18 | ethambutol | |
ubiA | 4269209 | p.Ser209Ala | missense_variant | 0.19 | ethambutol | |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin |