TB-Profiler result

Run: SRR29016901
Summary

Run ID: SRR29016901

Sample name:

Date: 2024-09-27T01:00:44.052937

Number of reads: 226319

Percentage reads mapped: 36.37

Median coverage: 2.0

Strain: La3;lineage4.9

Spoligotype:

Drug-resistance: Other

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.2.BCG M.bovis None 0.11
lineage4 Euro-American None 0.96
lineage4.9 Euro-American (H37Rv-like) None 0.93
La3 M.orygis None 0.07
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.His312Arg Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fbiC c.859_861delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fbiC 1303789 c.859_861delATCinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
embB 4247448 p.His312Arg missense_variant 1.0 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
hadA 731682 c.-248C>G upstream_gene_variant 1.0 isoniazid
hadA 731687 c.-243_-242insCACAGATCTTTT upstream_gene_variant 1.0 isoniazid
hadA 731693 c.-237C>A upstream_gene_variant 1.0 isoniazid
hadA 731696 c.-233_-232delTT upstream_gene_variant 1.0 isoniazid
hadA 731708 c.-222G>C upstream_gene_variant 1.0 isoniazid
hadA 731710 c.-220A>T upstream_gene_variant 1.0 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 1.0 isoniazid
hadA 731717 c.-213T>G upstream_gene_variant 0.93 isoniazid
hadA 731732 c.-198G>A upstream_gene_variant 1.0 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 1.0 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 1.0 isoniazid
hadA 732295 c.366G>C synonymous_variant 1.0 isoniazid
hadA 732305 p.Ile126Val missense_variant 1.0 isoniazid
hadA 732308 p.Val127Ile missense_variant 1.0 isoniazid
hadA 732321 p.Glu131Ala missense_variant 1.0 isoniazid
hadA 732329 p.Leu134Val missense_variant 1.0 isoniazid Uncertain significance
hadA 732337 c.408G>A synonymous_variant 1.0 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 1.0 isoniazid
hadA 732396 p.Gly156Ala missense_variant 1.0 isoniazid
hadA 732398 p.Ala157Thr missense_variant 1.0 isoniazid
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 1.0 rifampicin
nusG 734421 c.168A>G synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>A synonymous_variant 1.0 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734457 c.204C>G synonymous_variant 1.0 rifampicin
nusG 734472 c.219T>C synonymous_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 1.0 rifampicin
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 1.0 rifampicin
nusG 734596 c.343T>C synonymous_variant 1.0 rifampicin
nusG 734601 c.348C>G synonymous_variant 1.0 rifampicin
nusG 734610 c.357C>G synonymous_variant 1.0 rifampicin
nusG 734625 c.372T>C synonymous_variant 1.0 rifampicin
nusG 734631 c.378G>C synonymous_variant 1.0 rifampicin
nusG 734634 c.381G>C synonymous_variant 1.0 rifampicin
nusG 734637 c.384G>C synonymous_variant 1.0 rifampicin
nusG 734643 c.390G>C synonymous_variant 1.0 rifampicin
nusG 734652 c.399T>C synonymous_variant 1.0 rifampicin
nusG 734658 c.405A>G synonymous_variant 1.0 rifampicin Not assoc w R
nusG 734661 c.408A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734664 c.411T>G synonymous_variant 1.0 rifampicin
nusG 734673 c.420A>G synonymous_variant 1.0 rifampicin
nusG 734676 c.423G>C synonymous_variant 1.0 rifampicin
nusG 734679 c.426C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734680 c.427_429delGCCinsAG frameshift_variant&missense_variant 1.0 rifampicin
nusG 734703 c.450T>C synonymous_variant 1.0 rifampicin
nusG 734709 c.456T>G synonymous_variant 1.0 rifampicin
nusG 734772 c.519G>C synonymous_variant 0.91 rifampicin
nusG 734775 c.522C>G synonymous_variant 1.0 rifampicin
nusG 734781 c.528A>G synonymous_variant 1.0 rifampicin
nusG 734784 c.531G>A synonymous_variant 1.0 rifampicin
nusG 734787 c.534T>C synonymous_variant 1.0 rifampicin
nusG 734792 p.Val180Ala missense_variant 1.0 rifampicin
nusG 734794 p.Val181Ile missense_variant 1.0 rifampicin Uncertain significance
nusG 734814 c.561G>C synonymous_variant 1.0 rifampicin
nusG 734826 c.573A>C synonymous_variant 1.0 rifampicin
nusG 734829 c.576C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734841 c.588G>C synonymous_variant 1.0 rifampicin
nusG 734847 c.594T>C synonymous_variant 1.0 rifampicin
nusG 734850 c.597C>G synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734882 p.Ala210Gly missense_variant 1.0 rifampicin
rpoB 760091 c.285G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 1.0 rifampicin
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 1.0 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 1.0 rifampicin
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760412 c.606C>G synonymous_variant 1.0 rifampicin
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 1.0 rifampicin
rpoB 760541 c.735G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.95 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.95 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760715 c.909C>G synonymous_variant 0.93 rifampicin
rpoB 760718 c.912C>T synonymous_variant 0.93 rifampicin
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 1.0 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.9 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.88 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760934 c.1128C>T synonymous_variant 0.91 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760949 c.1143C>T synonymous_variant 0.92 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.97 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.97 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 1.0 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 1.0 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 1.0 rifampicin
rpoB 761219 c.1413G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 1.0 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 1.0 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.96 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.96 rifampicin
rpoB 761373 p.Val523His missense_variant 0.95 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.95 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.94 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.93 rifampicin
rpoB 761438 c.1632G>C synonymous_variant 0.93 rifampicin
rpoB 761439 c.1633_1635delGACinsAG frameshift_variant&missense_variant 0.93 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.93 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 0.93 rifampicin
rpoB 761452 p.Val549Glu missense_variant 0.93 rifampicin
rpoB 761457 p.Pro551Ser missense_variant 0.93 rifampicin
rpoB 761477 c.1671C>G synonymous_variant 0.91 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.91 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 0.96 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761588 c.1782C>T synonymous_variant 0.95 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.95 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761639 c.1833G>A synonymous_variant 0.97 rifampicin
rpoB 761645 c.1839C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.97 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.96 rifampicin
rpoB 761720 c.1914C>G synonymous_variant 0.88 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 0.87 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.87 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.88 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.88 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.83 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.83 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.84 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.83 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.82 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.76 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.84 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.85 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.85 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.88 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.88 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.9 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.87 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.87 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.87 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.87 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.87 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.97 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.85 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.85 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.83 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.87 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762206 c.2400C>G synonymous_variant 0.94 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762246 c.2440C>T synonymous_variant 0.94 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.94 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.94 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.94 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.96 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.96 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.96 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.94 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 762419 c.-951C>G upstream_gene_variant 0.94 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 0.94 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 762467 c.-903C>T upstream_gene_variant 0.92 rifampicin
rpoB 762488 c.2682G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.91 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.84 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.83 rifampicin
rpoC 762521 c.-849C>T upstream_gene_variant 0.83 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.83 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.82 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.82 rifampicin
rpoC 762551 c.-819C>G upstream_gene_variant 0.82 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.75 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.75 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 1.0 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 1.0 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762810 c.3004_3006delGCCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762813 p.Met1003Val missense_variant 1.0 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 1.0 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763013 c.-357C>G upstream_gene_variant 1.0 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 1.0 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763190 c.-180C>T upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.96 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 1.0 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763227 c.3421C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 1.0 rifampicin
rpoC 763256 c.-114G>A upstream_gene_variant 1.0 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763284 c.-86C>T upstream_gene_variant 1.0 rifampicin
rpoC 763402 c.33C>G synonymous_variant 0.92 rifampicin
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763441 c.72C>T synonymous_variant 1.0 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 1.0 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.97 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.97 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.97 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.97 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.96 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.96 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.96 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.95 rifampicin
rpoC 763853 p.Val162Ile missense_variant 0.97 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.97 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.96 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 0.73 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.73 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.75 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.79 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.77 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.85 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.85 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.85 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.86 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764112 p.Tyr248Phe missense_variant 0.81 rifampicin
rpoC 764116 c.747C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.85 rifampicin
rpoC 764140 c.771C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ile missense_variant 0.88 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.88 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764215 c.846A>G synonymous_variant 0.9 rifampicin
rpoC 764236 c.867G>A synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764248 c.879C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.95 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.96 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.96 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.96 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764338 c.969G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>C synonymous_variant 1.0 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 1.0 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.96 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.97 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764581 c.1212T>C synonymous_variant 0.97 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 0.97 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 0.97 rifampicin
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.97 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.96 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.95 rifampicin
rpoC 764932 c.1563C>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.95 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.97 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 0.97 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.96 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.91 rifampicin
rpoC 765292 c.1923G>C synonymous_variant 0.96 rifampicin
rpoC 765298 c.1929G>C synonymous_variant 1.0 rifampicin
rpoC 765300 p.Val644Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765329 p.Ser654Gly missense_variant 1.0 rifampicin
rpoC 765346 c.1977C>G synonymous_variant 1.0 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 1.0 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 1.0 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 1.0 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 1.0 rifampicin
rpoC 765613 p.His748Gln missense_variant 1.0 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 1.0 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 1.0 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 1.0 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.96 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.93 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.93 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.92 rifampicin
rpoC 766030 c.2661C>G synonymous_variant 0.92 rifampicin
rpoC 766036 c.2667C>T synonymous_variant 0.95 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.9 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.92 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.89 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.96 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.95 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.94 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 766168 c.2799C>T synonymous_variant 1.0 rifampicin
rpoC 766174 p.Asn935Lys missense_variant 1.0 rifampicin
rpoC 766178 p.Ile937Val missense_variant 1.0 rifampicin
rpoC 766258 c.2889T>C synonymous_variant 1.0 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766288 c.2919C>G synonymous_variant 1.0 rifampicin
rpoC 766327 c.2958C>A synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 1.0 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.94 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.95 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 0.96 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.96 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.96 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.96 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 0.96 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 1.0 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 0.95 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.95 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.95 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 1.0 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 1.0 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 1.0 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 1.0 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 1.0 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766673 p.Gly1102Asn missense_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766801 c.3432C>G synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 1.0 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 1.0 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 1.0 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 1.0 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 0.88 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.89 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.97 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.97 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.97 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.97 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.97 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.97 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.97 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.98 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.97 streptomycin
rpsL 781772 c.213C>A synonymous_variant 0.95 streptomycin
rpsL 781808 c.249C>T synonymous_variant 1.0 streptomycin
rpsL 781811 c.252C>T synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781838 c.279G>C synonymous_variant 1.0 streptomycin
rpsL 781841 c.282C>G synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.97 streptomycin
rpsL 781877 c.318T>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800537 c.-272C>T upstream_gene_variant 1.0 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.97 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.97 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.97 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.94 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.94 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.94 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.93 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.93 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.93 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.92 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.91 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.95 linezolid
rplC 800794 c.-15A>G upstream_gene_variant 1.0 linezolid
rplC 800796 c.-13A>G upstream_gene_variant 1.0 linezolid
rplC 800798 c.-10_-9delGG upstream_gene_variant 1.0 linezolid
rplC 800814 c.6A>G synonymous_variant 1.0 linezolid
rplC 800817 c.9A>T synonymous_variant 1.0 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 0.92 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.92 linezolid
rplC 800874 c.66A>G synonymous_variant 1.0 linezolid
rplC 800875 c.67_69delGTAinsAT frameshift_variant&missense_variant 1.0 linezolid
rplC 800880 c.72A>G synonymous_variant 1.0 linezolid
rplC 800889 c.81C>G synonymous_variant 1.0 linezolid
rplC 800892 c.84G>C synonymous_variant 1.0 linezolid
rplC 800907 c.99C>G synonymous_variant 1.0 linezolid
rplC 800916 c.108A>G synonymous_variant 0.92 linezolid
rplC 801171 c.363A>G synonymous_variant 0.9 linezolid
rplC 801174 c.366T>C synonymous_variant 0.92 linezolid
rplC 801195 c.387G>C synonymous_variant 0.9 linezolid
rplC 801207 c.399C>T synonymous_variant 0.95 linezolid
rplC 801246 c.438C>T synonymous_variant 0.97 linezolid
rplC 801249 c.441T>C synonymous_variant 0.97 linezolid
rplC 801255 c.447C>T synonymous_variant 0.97 linezolid
rplC 801264 c.456C>T synonymous_variant 0.97 linezolid
rplC 801267 c.459A>T synonymous_variant 0.93 linezolid
rplC 801270 c.462T>C synonymous_variant 0.93 linezolid
rplC 801276 c.468G>C synonymous_variant 0.96 linezolid
rplC 801279 c.471G>C synonymous_variant 0.96 linezolid
rplC 801282 c.474G>C synonymous_variant 0.96 linezolid
rplC 801285 c.477G>C synonymous_variant 0.97 linezolid
rplC 801300 c.492C>G synonymous_variant 0.94 linezolid
rplC 801309 c.501C>G synonymous_variant 0.94 linezolid
rplC 801312 c.504G>C synonymous_variant 0.93 linezolid
rplC 801321 c.513C>T synonymous_variant 0.96 linezolid Not assoc w R - Interim
rplC 801324 c.516T>C synonymous_variant 0.97 linezolid
rplC 801339 c.531T>C synonymous_variant 0.96 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.96 linezolid
rplC 801348 c.540T>G synonymous_variant 0.96 linezolid
rplC 801357 c.549T>C synonymous_variant 0.95 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.91 linezolid
rplC 801402 c.594T>C synonymous_variant 0.94 linezolid
rplC 801405 c.597T>C synonymous_variant 0.95 linezolid
rplC 801423 c.615G>C synonymous_variant 0.96 linezolid
rplC 801426 c.618C>G synonymous_variant 0.96 linezolid
rplC 801427 p.Met207Val missense_variant 0.96 linezolid
rplC 801438 c.630T>C synonymous_variant 1.0 linezolid
rplC 801442 p.Ile212Val missense_variant 1.0 linezolid
fbiC 1303632 c.702T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303641 c.711C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303650 c.720G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303728 c.798G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303761 c.831T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303797 c.867A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303836 c.906G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303845 c.915C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303846 p.Phe306Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303914 c.984C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303920 c.990C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303944 c.1014G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303953 p.Asp341Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303956 c.1026A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303971 c.1041T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303980 c.1050G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304711 p.Ala594Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304875 p.Ile649Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304883 p.Glu651Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304891 p.Ile654Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
atpE 1461149 c.105T>G synonymous_variant 0.92 bedaquiline
atpE 1461150 c.106_108delATCinsGT frameshift_variant&missense_variant 0.92 bedaquiline
atpE 1461158 c.114T>G synonymous_variant 0.92 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.92 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.92 bedaquiline
atpE 1461185 c.141G>T synonymous_variant 0.92 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.85 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.85 bedaquiline
rrs 1472300 n.455C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.83 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474409 n.756_766delACCCACACGCG non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474427 n.770A>C non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474429 n.772G>C non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474431 n.774_775delGCinsTTTGGG non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474435 n.780_783delGAAT non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475028 n.1371G>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1674537 c.336C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674552 c.351C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674555 c.354G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674601 p.Leu134Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674630 c.429C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674672 c.471C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674708 c.507G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674723 c.522C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674738 c.537C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674741 c.540C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674746 p.Tyr182Phe missense_variant 1.0 ethionamide
isoniazid
inhA 1674750 c.549T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674753 c.552G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674774 c.573A>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674789 c.588G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674822 c.621C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674828 c.627G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 1.0 ethionamide
isoniazid
inhA 1674855 c.654C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674864 c.663C>T synonymous_variant 0.95 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674870 c.669T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674879 c.678T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 1.0 ethionamide
isoniazid
inhA 1674909 c.708G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674942 c.741T>G synonymous_variant 1.0 ethionamide
isoniazid
rpsA 1833568 c.27G>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.88 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.89 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.92 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.91 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.95 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.95 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.95 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.95 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.96 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.97 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.94 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.93 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.93 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.94 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.94 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.95 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.95 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.95 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.97 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.96 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1834262 c.721_723delTCGinsAGC synonymous_variant 0.92 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.87 pyrazinamide
rpsA 1834333 c.792C>T synonymous_variant 0.86 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.9 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.96 pyrazinamide
rpsA 1834684 c.1143C>T synonymous_variant 0.93 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.93 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.92 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.9 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 0.9 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.89 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.88 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.88 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.88 pyrazinamide
bacA 2064933 c.-205A>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064936 c.-208C>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064942 c.-214G>A upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064948 c.-220G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
katG 2155704 c.408C>G synonymous_variant 0.92 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.94 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.94 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.94 isoniazid
katG 2155740 p.Gly124Gln missense_variant 0.94 isoniazid
katG 2155743 c.369G>C synonymous_variant 0.94 isoniazid
katG 2155782 c.330C>G synonymous_variant 0.93 isoniazid
katG 2155785 c.327T>C synonymous_variant 0.93 isoniazid
katG 2155794 p.Ala106Ser missense_variant 0.92 isoniazid
katG 2155806 c.306T>C synonymous_variant 0.92 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 0.94 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.92 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.91 isoniazid
kasA 2518413 p.Ser100Asn missense_variant 0.9 isoniazid
kasA 2518421 p.Val103Leu missense_variant 0.9 isoniazid
kasA 2518429 c.315A>C synonymous_variant 0.9 isoniazid
kasA 2518459 c.345T>C synonymous_variant 1.0 isoniazid
kasA 2518462 c.348A>C synonymous_variant 1.0 isoniazid
kasA 2518468 c.354A>C synonymous_variant 1.0 isoniazid
kasA 2518474 c.360G>A synonymous_variant 1.0 isoniazid
kasA 2518480 c.366T>C synonymous_variant 1.0 isoniazid
kasA 2518483 c.369C>G synonymous_variant 1.0 isoniazid
kasA 2518504 c.390T>C synonymous_variant 1.0 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 1.0 isoniazid
kasA 2518519 c.405G>C synonymous_variant 1.0 isoniazid
kasA 2518528 c.414C>G synonymous_variant 1.0 isoniazid
kasA 2518540 c.426T>C synonymous_variant 1.0 isoniazid
kasA 2518561 c.447T>C synonymous_variant 1.0 isoniazid
kasA 2518567 c.453G>C synonymous_variant 1.0 isoniazid
kasA 2518570 c.456G>C synonymous_variant 1.0 isoniazid
kasA 2518573 c.459G>C synonymous_variant 1.0 isoniazid
kasA 2518574 c.460_462delATCinsGG frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518579 c.465T>C synonymous_variant 1.0 isoniazid
kasA 2518588 c.474T>C synonymous_variant 1.0 isoniazid
kasA 2518591 c.477G>C synonymous_variant 1.0 isoniazid
kasA 2518609 p.Met165Ile missense_variant 1.0 isoniazid
kasA 2518624 c.510C>G synonymous_variant 1.0 isoniazid
kasA 2518639 c.525G>C synonymous_variant 1.0 isoniazid
kasA 2518657 c.543G>C synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518678 c.564C>T synonymous_variant 1.0 isoniazid
kasA 2518684 c.570C>G synonymous_variant 1.0 isoniazid
kasA 2518693 c.579C>G synonymous_variant 1.0 isoniazid
kasA 2518696 c.582C>G synonymous_variant 1.0 isoniazid
kasA 2518702 c.588C>T synonymous_variant 1.0 isoniazid
kasA 2518705 c.591T>C synonymous_variant 1.0 isoniazid
kasA 2518711 c.597A>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>C synonymous_variant 1.0 isoniazid
kasA 2518732 c.618C>G synonymous_variant 1.0 isoniazid
kasA 2518744 c.630C>T synonymous_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518768 c.654C>T synonymous_variant 1.0 isoniazid
kasA 2518777 c.663C>T synonymous_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518789 c.675G>C synonymous_variant 1.0 isoniazid
kasA 2518792 c.678C>A synonymous_variant 0.97 isoniazid
kasA 2518795 c.681C>G synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518864 c.750G>C synonymous_variant 1.0 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.95 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.94 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.94 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.94 isoniazid
kasA 2518910 p.Leu266Met missense_variant 0.94 isoniazid
kasA 2518921 c.807T>C synonymous_variant 0.88 isoniazid
kasA 2518936 c.822C>G synonymous_variant 0.87 isoniazid
kasA 2518939 c.825T>C synonymous_variant 0.87 isoniazid
kasA 2518942 c.828T>C synonymous_variant 0.87 isoniazid
kasA 2518951 c.837G>C synonymous_variant 0.88 isoniazid
kasA 2518954 c.840C>G synonymous_variant 0.88 isoniazid
kasA 2518963 c.849T>C synonymous_variant 0.88 isoniazid
kasA 2518969 c.855T>G synonymous_variant 0.88 isoniazid
kasA 2518975 c.861C>G synonymous_variant 0.88 isoniazid
kasA 2518979 c.865A>C synonymous_variant 0.88 isoniazid
kasA 2518990 c.876T>G synonymous_variant 0.86 isoniazid
kasA 2518993 c.879C>G synonymous_variant 0.85 isoniazid
kasA 2518999 c.885G>C synonymous_variant 0.85 isoniazid
kasA 2519008 c.894C>G synonymous_variant 0.8 isoniazid
kasA 2519050 c.936C>G synonymous_variant 0.91 isoniazid
kasA 2519056 c.942G>C synonymous_variant 0.83 isoniazid
kasA 2519062 c.948T>G synonymous_variant 0.92 isoniazid
kasA 2519068 c.954C>T synonymous_variant 1.0 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 1.0 isoniazid
kasA 2519095 c.981C>A synonymous_variant 1.0 isoniazid
kasA 2519116 c.1002C>G synonymous_variant 1.0 isoniazid
kasA 2519122 c.1008G>C synonymous_variant 1.0 isoniazid
Rv2477c 2783149 c.894G>C synonymous_variant 0.92 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.93 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783182 c.861C>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783185 c.858G>A synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 0.94 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783275 c.768C>G synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783293 c.750G>A synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783314 c.729C>G synonymous_variant 0.93 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783317 c.726G>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783839 c.204C>G synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.84 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783929 c.114C>G synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783932 c.111C>T synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 0.93 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2752c 3065979 c.213T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065993 p.Val67Ile missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066002 p.Met64Leu missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066009 c.183G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066018 c.174T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066024 c.168T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066774 c.-583T>C upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066780 c.-589C>G upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066807 c.-616T>C upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066810 c.-619G>A upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066819 c.-628T>C upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066822 c.-631T>C upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066834 c.-643G>C upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066839 c.-648A>G upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067223 c.723G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067232 c.714C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067246 p.Thr234Ala missense_variant 1.0 para-aminosalicylic_acid
thyX 3067249 p.Thr233Ser missense_variant 1.0 para-aminosalicylic_acid
thyX 3067250 c.694_696delGTGinsAC frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyX 3067274 c.672C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067277 c.669C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067281 p.Val222Ala missense_variant 0.92 para-aminosalicylic_acid
thyX 3067284 p.Ala221Gly missense_variant 1.0 para-aminosalicylic_acid
thyX 3067286 c.660C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067289 c.657C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067292 c.654G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067295 c.651C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067379 c.567C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067389 p.Thr186Ser missense_variant 1.0 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067445 c.501C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067465 p.Ile161Val missense_variant 1.0 para-aminosalicylic_acid
thyX 3067470 p.Asn159Ser missense_variant 1.0 para-aminosalicylic_acid
thyX 3067472 c.474C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067481 c.465C>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067490 c.456C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067493 c.453A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067515 p.Ser144Thr missense_variant 1.0 para-aminosalicylic_acid
thyX 3067530 p.Ala139Ser missense_variant 0.96 para-aminosalicylic_acid
thyX 3067545 p.Glu134Ala missense_variant 0.97 para-aminosalicylic_acid
thyX 3067549 p.Thr133Ala missense_variant 1.0 para-aminosalicylic_acid
thyX 3067556 p.His130Gln missense_variant 1.0 para-aminosalicylic_acid
thyX 3067559 c.387C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067565 p.Asp127Glu missense_variant 1.0 para-aminosalicylic_acid
thyX 3067570 p.Ala126Pro missense_variant 1.0 para-aminosalicylic_acid
thyX 3067577 c.369G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067601 p.Arg115His missense_variant 1.0 para-aminosalicylic_acid
thyX 3067611 p.Lys112Thr missense_variant 0.96 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067685 c.261A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067691 c.253_255delATCinsCG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067772 c.174C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 1.0 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067886 c.60A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 1.0 para-aminosalicylic_acid
thyA 3073824 c.648A>G synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3073827 c.645A>G synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 0.83 para-aminosalicylic_acid
thyA 3073860 c.612C>G synonymous_variant 0.86 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.86 para-aminosalicylic_acid
thyA 3073866 c.606C>G synonymous_variant 0.86 para-aminosalicylic_acid
thyA 3073872 c.598_600delATCinsGG frameshift_variant&missense_variant 0.86 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 0.94 para-aminosalicylic_acid
thyA 3073917 c.555C>G synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.89 para-aminosalicylic_acid
thyA 3073923 c.547_549delTTGinsCA frameshift_variant&missense_variant 0.94 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073947 c.525G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074010 c.462C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074028 c.444G>C synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 1.0 para-aminosalicylic_acid
thyA 3074055 p.Glu139Pro missense_variant 1.0 para-aminosalicylic_acid
thyA 3074061 c.411A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074079 c.393G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074100 c.370_372delGATinsAC frameshift_variant&synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074127 c.345G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074130 c.342G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074154 c.318T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074157 c.315C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074160 c.312A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074163 c.307_309delGCTinsAG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyA 3074172 c.300G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074181 c.291A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 1.0 para-aminosalicylic_acid
mtrB 3625569 c.1045T>C synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625572 p.Thr348Ser missense_variant 0.93 bedaquiline
rifampicin
lpqB 3625579 c.-669A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625612 c.-702G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625616 p.Arg333Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625636 c.978C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625656 c.958T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625669 c.-759G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625705 c.909C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625711 c.903C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625714 c.-804C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625735 c.-825C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625749 c.-839C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625750 c.864G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
mtrB 3625765 c.849C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625774 c.840G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625797 p.Val273Met missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625806 c.808A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625807 c.807C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625837 c.777C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625849 c.-939T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625876 c.738G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627065 c.-452G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627071 c.279G>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627074 c.-461G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
fbiB 3642620 c.1086T>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiB 3642656 c.1122G>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiB 3642659 c.1125C>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiB 3642668 c.1134A>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiB 3642677 c.1143A>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiB 3642680 c.1146A>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiB 3642684 c.1150T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiB 3642701 c.1167C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
rpoA 3877503 c.1005G>C synonymous_variant 0.8 rifampicin
rpoA 3877507 p.Gly334Ala missense_variant 0.82 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 0.77 rifampicin
rpoA 3877553 p.Glu319Gln missense_variant 0.88 rifampicin
rpoA 3877571 p.Pro313Ala missense_variant 0.92 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.96 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.98 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 0.96 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 1.0 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877791 c.717C>G synonymous_variant 1.0 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 1.0 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 1.0 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 1.0 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 1.0 rifampicin
rpoA 3877890 c.618C>T synonymous_variant 1.0 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 1.0 rifampicin
rpoA 3877900 p.Ser203Asn missense_variant 1.0 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 1.0 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 1.0 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877986 c.522G>C synonymous_variant 1.0 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 1.0 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 1.0 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 1.0 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878043 c.465G>A synonymous_variant 1.0 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 1.0 rifampicin
rpoA 3878058 c.450G>T synonymous_variant 1.0 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 1.0 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 1.0 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 1.0 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 1.0 rifampicin
rpoA 3878082 c.426T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878094 c.414C>G synonymous_variant 1.0 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 1.0 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 1.0 rifampicin
rpoA 3878141 p.Met123Leu missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878143 p.Gly122Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878157 c.351C>G synonymous_variant 1.0 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 1.0 rifampicin
rpoA 3878181 c.327C>T synonymous_variant 1.0 rifampicin
rpoA 3878187 c.321C>G synonymous_variant 1.0 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 1.0 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878226 c.282C>G synonymous_variant 0.97 rifampicin
rpoA 3878232 c.276G>C synonymous_variant 0.97 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.97 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878284 p.Glu75Ala missense_variant 0.94 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.94 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878340 c.168C>T synonymous_variant 0.94 rifampicin
rpoA 3878346 c.162T>C synonymous_variant 0.92 rifampicin
rpoA 3878364 c.144A>T synonymous_variant 0.92 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.92 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 0.95 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.94 rifampicin
rpoA 3878388 c.120C>G synonymous_variant 0.94 rifampicin
rpoA 3878391 c.117T>C synonymous_variant 0.94 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.93 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.87 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.88 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.88 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 0.83 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.8 rifampicin
rpoA 3878478 c.30C>G synonymous_variant 0.77 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 0.77 rifampicin
rpoA 3878490 c.18C>A synonymous_variant 0.75 rifampicin
rpoA 3878713 c.-206G>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878716 c.-209C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878736 c.-229A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878737 c.-230G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878749 c.-242G>T upstream_gene_variant 1.0 rifampicin
rpoA 3878761 c.-254G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878785 c.-278T>G upstream_gene_variant 1.0 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878806 c.-299C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878836 c.-331_-329delAAGinsTCC upstream_gene_variant 1.0 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878860 c.-353C>T upstream_gene_variant 1.0 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878909 c.-402A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878917 c.-410G>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878938 c.-431T>A upstream_gene_variant 1.0 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878962 c.-455G>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878968 c.-461T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878986 c.-479G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.97 rifampicin Uncertain significance
rpoA 3879005 c.-499_-498delAAinsCG upstream_gene_variant 0.94 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 0.94 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.96 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.96 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.96 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.93 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.95 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879178 c.-671T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 1.0 rifampicin
clpC1 4038596 c.2109A>G synonymous_variant 0.92 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.94 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.95 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.91 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.91 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.91 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.9 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.91 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.89 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.94 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.94 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.94 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038749 c.1956C>G synonymous_variant 0.94 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.95 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.94 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.93 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.95 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.96 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTG frameshift_variant&synonymous_variant 0.96 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.95 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 0.9 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.93 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039805 c.900C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039898 c.807C>G synonymous_variant 0.9 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.93 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.94 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039982 c.723G>A synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4039988 c.717C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.96 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.96 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.94 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.9 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.83 pyrazinamide
clpC1 4040318 c.387C>G synonymous_variant 0.86 pyrazinamide
clpC1 4040330 c.375C>G synonymous_variant 0.86 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 0.86 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.86 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.86 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.88 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.86 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.85 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.86 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.9 pyrazinamide
panD 4044682 c.-401C>A upstream_gene_variant 1.0 pyrazinamide
panD 4044688 c.-407T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044692 c.-411G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044700 c.-419C>A upstream_gene_variant 1.0 pyrazinamide
panD 4044704 c.-423G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044712 c.-431C>A upstream_gene_variant 0.94 pyrazinamide
panD 4044725 c.-444C>T upstream_gene_variant 1.0 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044746 c.-467_-465delGTGinsAC upstream_gene_variant 1.0 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044779 c.-500_-498delCTAinsTGC upstream_gene_variant 1.0 pyrazinamide
panD 4044788 c.-507G>C upstream_gene_variant 0.95 pyrazinamide
panD 4044791 c.-510G>C upstream_gene_variant 0.95 pyrazinamide
panD 4044800 c.-519C>G upstream_gene_variant 0.95 pyrazinamide
panD 4044812 c.-531A>C upstream_gene_variant 0.95 pyrazinamide
panD 4044818 c.-538_-537delCGinsAC upstream_gene_variant 0.95 pyrazinamide
panD 4044823 c.-542G>C upstream_gene_variant 0.95 pyrazinamide
panD 4044833 c.-552A>G upstream_gene_variant 0.95 pyrazinamide
panD 4044844 c.-563T>C upstream_gene_variant 0.96 pyrazinamide
panD 4044848 c.-567T>A upstream_gene_variant 0.96 pyrazinamide
panD 4044854 c.-573A>G upstream_gene_variant 0.96 pyrazinamide
panD 4044860 c.-579C>G upstream_gene_variant 0.96 pyrazinamide
panD 4044872 c.-591C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044890 c.-609G>C upstream_gene_variant 0.95 pyrazinamide
panD 4044895 c.-614A>G upstream_gene_variant 0.94 pyrazinamide
panD 4044896 c.-615T>G upstream_gene_variant 0.94 pyrazinamide
panD 4044902 c.-623_-621delACGinsGC upstream_gene_variant 0.94 pyrazinamide
panD 4044908 c.-628_-627delCTinsTC upstream_gene_variant 0.88 pyrazinamide
panD 4044917 c.-636G>C upstream_gene_variant 0.95 pyrazinamide
panD 4044926 c.-645C>A upstream_gene_variant 0.95 pyrazinamide
panD 4044929 c.-648G>C upstream_gene_variant 0.95 pyrazinamide
panD 4044935 c.-655_-654delAAinsTG upstream_gene_variant 0.95 pyrazinamide
panD 4044941 c.-660G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044954 c.-674_-673delCCinsAT upstream_gene_variant 1.0 pyrazinamide
panD 4044980 c.-699A>G upstream_gene_variant 1.0 pyrazinamide
panD 4044983 c.-702G>T upstream_gene_variant 1.0 pyrazinamide
panD 4044989 c.-708T>C upstream_gene_variant 1.0 pyrazinamide
panD 4045000 c.-719A>C upstream_gene_variant 1.0 pyrazinamide
panD 4045001 c.-720G>C upstream_gene_variant 1.0 pyrazinamide
panD 4045019 c.-738G>C upstream_gene_variant 1.0 pyrazinamide
panD 4045022 c.-741C>G upstream_gene_variant 1.0 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 1.0 pyrazinamide
panD 4045034 c.-753A>C upstream_gene_variant 0.95 pyrazinamide
panD 4045055 c.-774T>G upstream_gene_variant 1.0 pyrazinamide
panD 4045067 c.-786C>G upstream_gene_variant 1.0 pyrazinamide
panD 4045070 c.-789C>T upstream_gene_variant 1.0 pyrazinamide
panD 4045076 c.-795A>C upstream_gene_variant 1.0 pyrazinamide
panD 4045088 c.-807T>C upstream_gene_variant 1.0 pyrazinamide
panD 4045094 c.-813T>C upstream_gene_variant 1.0 pyrazinamide
panD 4045097 c.-816T>C upstream_gene_variant 0.94 pyrazinamide
panD 4045105 c.-824T>C upstream_gene_variant 0.88 pyrazinamide
panD 4045112 c.-831A>G upstream_gene_variant 0.83 pyrazinamide
panD 4045115 c.-834G>C upstream_gene_variant 0.83 pyrazinamide
glpK 4138490 c.1266G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138495 p.Gln421Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138496 c.1260G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138502 c.1254T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138511 c.1245C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138514 c.1242A>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138517 p.Glu413Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138523 c.1233C>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138529 c.1227G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138535 c.1221T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138622 c.1134C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138646 c.1110G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138654 c.1102C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138670 c.1086G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138679 c.1075_1077delATGinsGC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138695 p.Pro354Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138721 c.1035G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138724 c.1032A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138730 c.1026C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138763 c.993G>A synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138769 c.987G>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138774 p.Ser328Ala missense_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138778 c.978C>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138796 c.960A>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138802 c.954G>A synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138808 c.948G>T synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138817 c.939T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138822 p.Asn312Asp missense_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138829 c.927A>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138838 c.918G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138841 c.915G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138847 c.909A>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138853 c.903C>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138859 c.895_897delAATinsGC frameshift_variant&missense_variant 0.92 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138862 c.894G>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138865 c.891A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 1.0 ethambutol
embC 4240781 c.919_921delGCGinsTC frameshift_variant&missense_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240819 c.957A>G synonymous_variant 1.0 ethambutol
embC 4240828 c.966G>A synonymous_variant 1.0 ethambutol
embC 4240831 c.969T>G synonymous_variant 1.0 ethambutol
embC 4241089 c.1227C>G synonymous_variant 1.0 ethambutol
embC 4241095 c.1233C>T synonymous_variant 1.0 ethambutol
embC 4241107 c.1245G>C synonymous_variant 1.0 ethambutol
embC 4241140 c.1278A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241146 c.1284C>G synonymous_variant 1.0 ethambutol
embC 4241158 c.1296T>C synonymous_variant 1.0 ethambutol
embC 4241161 c.1299C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 1.0 ethambutol
embC 4241170 c.1308G>C synonymous_variant 1.0 ethambutol
embC 4241173 c.1311C>T synonymous_variant 1.0 ethambutol
embC 4241203 c.1341T>C synonymous_variant 1.0 ethambutol
embC 4241206 c.1344G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245785 c.2553G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245807 c.2575_2577delTTAinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embB 4245812 c.-702G>C upstream_gene_variant 1.0 ethambutol
embA 4245813 c.2581_2583delCCCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4245820 p.Ser863Thr missense_variant 1.0 ethambutol
embB 4245824 c.-690G>C upstream_gene_variant 1.0 ethambutol
embB 4245833 c.-681G>C upstream_gene_variant 1.0 ethambutol
embB 4245842 c.-672G>C upstream_gene_variant 1.0 ethambutol
embB 4245845 c.-669T>C upstream_gene_variant 1.0 ethambutol
embB 4245851 c.-663G>C upstream_gene_variant 1.0 ethambutol
embB 4245860 c.-654C>G upstream_gene_variant 1.0 ethambutol
embB 4247386 c.873T>C synonymous_variant 1.0 ethambutol
embB 4247395 c.882C>G synonymous_variant 1.0 ethambutol
embB 4247401 c.888T>C synonymous_variant 1.0 ethambutol
embB 4247407 c.894G>C synonymous_variant 1.0 ethambutol
embB 4247425 c.912G>C synonymous_variant 1.0 ethambutol
embB 4247434 c.921C>G synonymous_variant 1.0 ethambutol
embB 4247437 c.924A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247440 c.927C>G synonymous_variant 1.0 ethambutol
embB 4247446 c.933C>T synonymous_variant 1.0 ethambutol
embB 4247464 c.951C>G synonymous_variant 1.0 ethambutol
embB 4247470 c.957T>C synonymous_variant 1.0 ethambutol
embB 4247491 c.978G>C synonymous_variant 1.0 ethambutol
embB 4247497 c.984T>C synonymous_variant 1.0 ethambutol
embB 4247512 c.999T>C synonymous_variant 1.0 ethambutol
embB 4247974 c.1461C>G synonymous_variant 1.0 ethambutol
embB 4248007 c.1494C>G synonymous_variant 1.0 ethambutol
embB 4248011 p.Ser500Arg missense_variant 1.0 ethambutol
embB 4248014 p.Thr501Ala missense_variant 1.0 ethambutol Uncertain significance
embB 4248035 p.Val508Ile missense_variant 1.0 ethambutol
embB 4248040 c.1527C>G synonymous_variant 0.93 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.93 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 1.0 ethambutol
embB 4248070 c.1557T>C synonymous_variant 1.0 ethambutol
embB 4248085 c.1572T>C synonymous_variant 1.0 ethambutol
embB 4248097 c.1584C>G synonymous_variant 1.0 ethambutol
embB 4248130 c.1617G>C synonymous_variant 1.0 ethambutol
embB 4248142 c.1629T>C synonymous_variant 1.0 ethambutol
embB 4248143 c.1630T>C synonymous_variant 1.0 ethambutol
embB 4248157 c.1644A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248172 c.1659G>C synonymous_variant 1.0 ethambutol
embB 4248199 c.1686A>G synonymous_variant 1.0 ethambutol
embB 4248200 p.Ile563Val missense_variant 1.0 ethambutol
embB 4248205 c.1692C>G synonymous_variant 1.0 ethambutol
embB 4248206 c.1693_1695delAGCinsGT frameshift_variant&missense_variant 1.0 ethambutol
embB 4248220 c.1707A>C synonymous_variant 1.0 ethambutol