TB-Profiler result

Run: SRR18003023
Summary

Run ID: SRR18003023

Sample name:

Date: 03-04-2023 19:14:26

Number of reads: 1299585

Percentage reads mapped: 35.04

Strain: lineage2.2.1

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 1.0
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 1.0
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.31 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.4 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.61 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.54 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7824 p.Ala175Thr missense_variant 0.14
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.28
ccsA 620625 p.Ile245Met missense_variant 1.0
ccsA 620824 c.934C>T synonymous_variant 0.13
ccsA 620830 p.Thr314Ala missense_variant 0.13
rpoB 762038 c.2232C>T synonymous_variant 0.17
rpoB 762658 p.Ala951Val missense_variant 0.12
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763295 c.-75C>T upstream_gene_variant 0.13
rpoC 763603 c.234C>T synonymous_variant 0.14
rpoC 763606 c.237C>G synonymous_variant 0.17
rpoC 763615 c.246G>T synonymous_variant 0.22
rpoC 763618 c.249C>T synonymous_variant 0.23
rpoC 763622 p.Ala85Ser missense_variant 0.24
rpoC 763633 c.264T>C synonymous_variant 0.27
rpoC 763642 c.273G>C synonymous_variant 0.27
rpoC 763648 c.279C>T synonymous_variant 0.33
rpoC 763655 p.Glu96Lys missense_variant 0.35
rpoC 763660 c.291T>G synonymous_variant 0.35
rpoC 763666 c.297G>T synonymous_variant 0.35
rpoC 763669 c.300C>G synonymous_variant 0.36
rpoC 763672 c.303C>A synonymous_variant 0.32
rpoC 763675 c.306C>T synonymous_variant 0.36
rpoC 763702 c.333C>T synonymous_variant 0.29
rpoC 763705 c.336G>A synonymous_variant 0.29
rpoC 763708 c.339G>C synonymous_variant 0.32
rpoC 763714 c.345G>C synonymous_variant 0.32
rpoC 763717 c.348T>C synonymous_variant 0.3
rpoC 763723 c.354G>C synonymous_variant 0.3
rpoC 763724 p.Asp119Asn missense_variant 0.3
rpoC 763735 c.366G>C synonymous_variant 0.3
rpoC 763744 c.375G>A synonymous_variant 0.3
rpoC 763751 p.Ile128Val missense_variant 0.27
rpoC 763756 c.387C>T synonymous_variant 0.25
rpoC 763765 c.396T>C synonymous_variant 0.2
rpoC 763768 c.399C>T synonymous_variant 0.18
rpoC 763772 p.Val135Met missense_variant 0.18
rpoC 763781 p.Ser138Ala missense_variant 0.14
rpoC 764746 c.1377G>C synonymous_variant 0.1
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776373 p.Arg703Pro missense_variant 0.14
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406760 c.580_581insC frameshift_variant 0.96
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471995 n.150C>T non_coding_transcript_exon_variant 0.4
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 1.0
rrs 1472080 n.235G>A non_coding_transcript_exon_variant 0.2
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.29
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.3
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.72
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.25
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.24
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.55
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.55
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.55
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.88
rrs 1472150 n.305T>G non_coding_transcript_exon_variant 0.91
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.58
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.56
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.38
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.88
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.38
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.25
rrs 1472404 n.559G>A non_coding_transcript_exon_variant 0.25
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.22
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.25
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.25
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.25
rrs 1472436 n.591G>T non_coding_transcript_exon_variant 0.25
rrs 1472437 n.592T>G non_coding_transcript_exon_variant 0.25
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.25
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.25
rrs 1472449 n.604C>T non_coding_transcript_exon_variant 0.25
rrs 1472450 n.605A>C non_coding_transcript_exon_variant 0.25
rrs 1472451 n.606C>T non_coding_transcript_exon_variant 0.25
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 0.29
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.29
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.29
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.29
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.5
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.81
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.8
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.81
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.24
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.15
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.27
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.29
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.38
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.37
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.36
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.33
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.16
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.56
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.32
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.55
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.41
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.19
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.32
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.86
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.97
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.16
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.39
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.38
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.34
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.37
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.42
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.98
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.98
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.41
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.59
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.41
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.55
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.56
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.42
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.41
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.58
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.41
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.41
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.41
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.31
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.3
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.22
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.22
rrs 1472865 n.1020C>T non_coding_transcript_exon_variant 0.18
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.33
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.71
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.41
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.41
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.87
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.41
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.47
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.88
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.49
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.43
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.46
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.4
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.89
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.95
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.96
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.97
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.96
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.25
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.96
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.96
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.97
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.94
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.95
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.95
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.96
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.9
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.95
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.45
rrs 1473129 n.1284C>T non_coding_transcript_exon_variant 0.41
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.96
rrs 1473148 n.1303G>T non_coding_transcript_exon_variant 0.42
rrs 1473163 n.1318C>A non_coding_transcript_exon_variant 0.37
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.95
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.35
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.34
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.32
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.91
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.91
rrs 1473262 n.1417T>C non_coding_transcript_exon_variant 0.25
rrs 1473270 n.1425G>A non_coding_transcript_exon_variant 0.84
rrs 1473270 n.1425G>C non_coding_transcript_exon_variant 0.69
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.72
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.86
rrs 1473281 n.1436_1437insT non_coding_transcript_exon_variant 0.25
rrs 1473285 n.1440_1444delACCCT non_coding_transcript_exon_variant 0.69
rrs 1473291 n.1449_1451delAGG non_coding_transcript_exon_variant 0.27
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.81
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.66
rrs 1473304 n.1459C>T non_coding_transcript_exon_variant 0.28
rrs 1473305 n.1460G>A non_coding_transcript_exon_variant 0.69
rrs 1473305 n.1460G>T non_coding_transcript_exon_variant 0.83
rrs 1473314 n.1469A>G non_coding_transcript_exon_variant 0.28
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.28
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.86
rrs 1473317 n.1472G>A non_coding_transcript_exon_variant 0.28
rrl 1474124 n.467G>C non_coding_transcript_exon_variant 0.44
rrl 1474125 n.468C>G non_coding_transcript_exon_variant 0.44
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.5
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.62
rrl 1474141 n.484G>C non_coding_transcript_exon_variant 0.62
rrl 1474142 n.485C>G non_coding_transcript_exon_variant 0.62
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.62
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 0.62
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.62
rrl 1474171 n.514C>T non_coding_transcript_exon_variant 0.56
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.56
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.56
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.56
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.56
rrl 1474199 n.542G>A non_coding_transcript_exon_variant 0.56
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 0.56
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.83
rrl 1474264 n.607T>G non_coding_transcript_exon_variant 0.27
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.28
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.83
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.83
rrl 1474280 n.623C>T non_coding_transcript_exon_variant 0.55
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.55
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.28
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.57
rrl 1474317 n.660G>A non_coding_transcript_exon_variant 0.57
rrl 1474326 n.669T>A non_coding_transcript_exon_variant 0.3
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.89
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.89
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.73
rrl 1474353 n.696A>T non_coding_transcript_exon_variant 0.84
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.59
rrl 1474355 n.698A>G non_coding_transcript_exon_variant 0.3
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.92
rrl 1474381 n.724T>G non_coding_transcript_exon_variant 0.26
rrl 1474383 n.726G>T non_coding_transcript_exon_variant 0.86
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.83
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.78
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.5
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.45
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.93
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.52
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.46
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.41
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.48
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.49
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.38
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.4
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.57
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.94
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.93
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.91
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.93
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.91
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.93
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.4
rrl 1474584 n.927C>T non_coding_transcript_exon_variant 0.42
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.38
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.38
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 1.0
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 1.0
rrl 1474637 n.980C>G non_coding_transcript_exon_variant 1.0
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 1.0
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.36
rrl 1474643 n.986A>G non_coding_transcript_exon_variant 0.65
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.66
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.99
rrl 1474674 n.1017A>C non_coding_transcript_exon_variant 0.3
rrl 1474675 n.1018C>A non_coding_transcript_exon_variant 0.3
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.98
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.96
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 1.0
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 0.67
rrl 1474694 n.1037C>T non_coding_transcript_exon_variant 0.3
rrl 1474706 n.1049G>A non_coding_transcript_exon_variant 0.67
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 0.91
rrl 1474717 n.1060_1061insGTGAG non_coding_transcript_exon_variant 0.91
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 0.97
rrl 1474723 n.1066G>A non_coding_transcript_exon_variant 0.27
rrl 1474734 n.1077G>A non_coding_transcript_exon_variant 0.97
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.27
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.24
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.19
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.91
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.31
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.29
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.3
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.25
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.94
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.38
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.57
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.38
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.8
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.71
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.89
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.51
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.87
rrl 1474883 n.1226T>C non_coding_transcript_exon_variant 0.34
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.47
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.43
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.49
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.46
rrl 1475059 n.1403_1404insTA non_coding_transcript_exon_variant 0.55
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.55
rrl 1475065 n.1409_1411delCAA non_coding_transcript_exon_variant 0.55
rrl 1475080 n.1425_1426delCC non_coding_transcript_exon_variant 0.46
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.46
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.46
rrl 1475109 n.1452C>T non_coding_transcript_exon_variant 0.46
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.43
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.4
rrl 1475137 n.1480A>T non_coding_transcript_exon_variant 0.4
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 0.38
rrl 1475175 n.1518G>C non_coding_transcript_exon_variant 0.4
rrl 1475655 n.1998T>G non_coding_transcript_exon_variant 0.3
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.46
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.29
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.31
rrl 1475686 n.2029C>G non_coding_transcript_exon_variant 0.48
rrl 1475696 n.2039T>C non_coding_transcript_exon_variant 0.45
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.89
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 0.43
rrl 1475715 n.2058G>C non_coding_transcript_exon_variant 0.41
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.51
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.75
rrl 1475751 n.2094C>T non_coding_transcript_exon_variant 0.77
rrl 1475752 n.2095C>T non_coding_transcript_exon_variant 0.46
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.46
rrl 1475756 n.2101A>G non_coding_transcript_exon_variant 0.8
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.47
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.45
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.43
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.5
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.54
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.94
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.96
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.97
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.96
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.93
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.66
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.95
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.26
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.95
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.74
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.92
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.91
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.91
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 0.73
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.92
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.12
rrl 1475992 n.2335T>G non_coding_transcript_exon_variant 0.12
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.79
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.78
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.91
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.91
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.81
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.81
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.81
rrl 1476040 n.2383C>T non_coding_transcript_exon_variant 0.81
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.81
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.81
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.81
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.33
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 0.29
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 0.38
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.86
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.17
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.24
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.59
rrl 1476164 n.2507A>T non_coding_transcript_exon_variant 0.51
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.23
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.31
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.93
rrl 1476194 n.2537A>T non_coding_transcript_exon_variant 0.89
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.25
rrl 1476196 n.2539C>A non_coding_transcript_exon_variant 0.25
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.96
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.6
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.41
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.31
rrl 1476210 n.2553G>T non_coding_transcript_exon_variant 0.21
rrl 1476211 n.2554G>T non_coding_transcript_exon_variant 0.21
rrl 1476212 n.2555T>C non_coding_transcript_exon_variant 0.2
rrl 1476214 n.2557G>C non_coding_transcript_exon_variant 0.79
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.94
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.81
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.94
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.75
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.21
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.17
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.2
rrl 1476235 n.2578A>G non_coding_transcript_exon_variant 0.13
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.4
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.27
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.31
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.66
rrl 1476253 n.2596A>G non_coding_transcript_exon_variant 0.37
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.66
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.27
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.97
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 0.27
rrl 1476276 n.2619C>A non_coding_transcript_exon_variant 0.26
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.26
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.39
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.58
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.33
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.95
rrl 1476295 n.2638C>A non_coding_transcript_exon_variant 0.87
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.94
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.97
rrl 1476297 n.2640C>A non_coding_transcript_exon_variant 0.54
rrl 1476299 n.2642C>G non_coding_transcript_exon_variant 0.33
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.34
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.98
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.34
rrl 1476306 n.2649A>G non_coding_transcript_exon_variant 0.28
rrl 1476307 n.2650A>T non_coding_transcript_exon_variant 0.27
rrl 1476308 n.2651G>C non_coding_transcript_exon_variant 0.34
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.97
rrl 1476311 n.2654G>T non_coding_transcript_exon_variant 0.93
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.97
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.35
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.44
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.3
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.47
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.47
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.2
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.51
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.46
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.43
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.52
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.42
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.51
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.52
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.45
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.73
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.71
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.63
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.67
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.9
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.33
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.14
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.74
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.14
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.82
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.83
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.47
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.82
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.38
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.8
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.83
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.5
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.15
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.65
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.54
rrl 1476592 n.2935G>A non_coding_transcript_exon_variant 0.41
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 0.18
rrl 1476596 n.2939C>T non_coding_transcript_exon_variant 0.41
rrl 1476603 n.2946G>T non_coding_transcript_exon_variant 0.25
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.44
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.33
rrl 1476613 n.2956G>A non_coding_transcript_exon_variant 0.38
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.43
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.38
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.5
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.6
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.67
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.67
rrl 1476744 n.3087G>A non_coding_transcript_exon_variant 0.15
rpsA 1833623 p.Lys28Glu missense_variant 0.21
rpsA 1833628 c.87G>C synonymous_variant 0.2
rpsA 1833641 p.Asn34Asp missense_variant 0.19
rpsA 1833658 c.117C>T synonymous_variant 0.2
rpsA 1833661 c.120A>G synonymous_variant 0.19
rpsA 1833668 p.Ile43Val missense_variant 0.19
rpsA 1833673 c.132C>T synonymous_variant 0.19
rpsA 1833676 c.135A>G synonymous_variant 0.19
rpsA 1833679 c.138G>T synonymous_variant 0.2
rpsA 1833685 c.144G>C synonymous_variant 0.18
rpsA 1833694 c.153G>C synonymous_variant 0.17
rpsA 1833718 c.177C>T synonymous_variant 0.18
rpsA 1833721 c.180A>G synonymous_variant 0.22
rpsA 1833727 c.186G>T synonymous_variant 0.17
rpsA 1833732 p.Pro64Leu missense_variant 0.14
rpsA 1833734 p.Ala65Ser missense_variant 0.14
rpsA 1833742 c.201A>G synonymous_variant 0.14
rpsA 1833835 c.294C>T synonymous_variant 0.17
rpsA 1833952 c.411C>T synonymous_variant 0.16
rpsA 1833955 c.414G>C synonymous_variant 0.3
rpsA 1833967 c.426C>T synonymous_variant 0.14
rpsA 1833970 c.429G>T synonymous_variant 0.3
rpsA 1833979 c.438T>C synonymous_variant 0.29
rpsA 1833985 c.444G>A synonymous_variant 0.16
rpsA 1833991 c.450C>T synonymous_variant 0.18
rpsA 1833994 c.453G>C synonymous_variant 0.29
rpsA 1833997 c.456G>C synonymous_variant 0.13
rpsA 1834000 c.459G>T synonymous_variant 0.29
rpsA 1834003 c.462G>A synonymous_variant 0.15
rpsA 1834009 c.468C>T synonymous_variant 0.16
rpsA 1834012 c.471G>C synonymous_variant 0.31
rpsA 1834015 c.474G>C synonymous_variant 0.17
rpsA 1834024 c.483G>C synonymous_variant 0.17
rpsA 1834025 p.Gln162Ala missense_variant 0.14
rpsA 1834034 p.Ile165Val missense_variant 0.16
rpsA 1834040 p.Lys167Arg missense_variant 0.28
rpsA 1834043 p.Glu168Gln missense_variant 0.12
rpsA 1834046 p.Ile169Leu missense_variant 0.15
rpsA 1834060 c.519C>T synonymous_variant 0.16
rpsA 1834177 c.636A>C synonymous_variant 1.0
rpsA 1834261 c.720A>G synonymous_variant 0.12
rpsA 1834264 c.723G>C synonymous_variant 0.12
rpsA 1834298 p.Gln253Glu missense_variant 0.11
rpsA 1834306 c.765T>C synonymous_variant 0.12
rpsA 1834307 p.Asp256Gln missense_variant 0.12
rpsA 1834327 c.786G>C synonymous_variant 0.14
rpsA 1834330 c.789C>G synonymous_variant 0.14
rpsA 1834333 c.792C>T synonymous_variant 0.14
rpsA 1834336 c.795C>G synonymous_variant 0.13
rpsA 1834342 p.Met267Ile missense_variant 0.14
rpsA 1834348 c.807T>C synonymous_variant 0.13
rpsA 1834357 c.816T>C synonymous_variant 0.12
rpsA 1834360 c.819G>C synonymous_variant 0.12
rpsA 1834361 c.820T>C synonymous_variant 0.12
rpsA 1834366 c.825A>C synonymous_variant 0.12
rpsA 1834378 c.837T>C synonymous_variant 0.12
rpsA 1834523 p.Glu328Gln missense_variant 0.13
rpsA 1834528 c.987T>C synonymous_variant 0.11
rpsA 1834546 p.Asp335Glu missense_variant 0.12
rpsA 1834570 p.Asp343Glu missense_variant 0.12
rpsA 1834574 p.Met345Phe missense_variant 0.13
rpsA 1834603 p.Glu354Asp missense_variant 0.14
rpsA 1834606 c.1065C>T synonymous_variant 0.14
rpsA 1834609 c.1068T>C synonymous_variant 0.14
rpsA 1834612 c.1071G>C synonymous_variant 0.13
rpsA 1834618 c.1077G>C synonymous_variant 0.14
rpsA 1834619 c.1078T>C synonymous_variant 0.14
rpsA 1834633 c.1092A>G synonymous_variant 0.13
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918703 p.Gly255Glu missense_variant 0.14
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2170233 p.Gly127Asp missense_variant 0.12
Rv1979c 2223061 p.Thr35Asn missense_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518911 p.Leu266Pro missense_variant 0.14
eis 2714512 p.Pro274Leu missense_variant 0.15
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339749 p.Val211Ala missense_variant 0.12
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612460 c.657G>A synonymous_variant 0.13
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
alr 3840913 p.Ala170Thr missense_variant 0.14
rpoA 3878619 c.-112A>C upstream_gene_variant 0.22
clpC1 4039724 c.981A>G synonymous_variant 0.11
clpC1 4039730 c.975C>G synonymous_variant 0.11
clpC1 4039733 c.972G>C synonymous_variant 0.11
clpC1 4039748 c.957G>C synonymous_variant 0.11
clpC1 4039751 c.954A>G synonymous_variant 0.11
clpC1 4039760 c.945T>C synonymous_variant 0.11
clpC1 4039778 c.927A>G synonymous_variant 0.12
clpC1 4039781 c.924G>C synonymous_variant 0.19
clpC1 4039787 c.918G>C synonymous_variant 0.17
clpC1 4039793 c.912C>T synonymous_variant 0.17
clpC1 4039799 c.906C>T synonymous_variant 0.18
clpC1 4039838 p.Leu289Ile missense_variant 0.14
clpC1 4039847 c.858C>T synonymous_variant 0.19
clpC1 4039850 c.855T>C synonymous_variant 0.17
clpC1 4039865 c.840T>C synonymous_variant 0.18
clpC1 4039873 p.Thr278Ser missense_variant 0.17
clpC1 4039875 p.Asn277Arg missense_variant 0.17
clpC1 4039880 c.825G>A synonymous_variant 0.19
clpC1 4039886 c.819C>G synonymous_variant 0.19
clpC1 4039889 c.816G>C synonymous_variant 0.22
clpC1 4039898 c.807C>G synonymous_variant 0.21
clpC1 4039904 c.801A>G synonymous_variant 0.24
clpC1 4039907 c.798G>A synonymous_variant 0.3
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.32
clpC1 4039934 c.771G>A synonymous_variant 0.29
clpC1 4039937 c.768G>C synonymous_variant 0.31
clpC1 4039943 c.762G>C synonymous_variant 0.31
clpC1 4039946 c.759A>C synonymous_variant 0.32
clpC1 4039952 c.753T>C synonymous_variant 0.32
clpC1 4039958 c.747G>C synonymous_variant 0.31
clpC1 4039964 c.741C>G synonymous_variant 0.29
clpC1 4039967 p.Gln246His missense_variant 0.29
clpC1 4039982 c.723G>C synonymous_variant 0.27
clpC1 4039991 c.714G>C synonymous_variant 0.22
clpC1 4039994 p.Glu237Asp missense_variant 0.21
clpC1 4039997 c.708C>T synonymous_variant 0.22
clpC1 4040009 c.696C>T synonymous_variant 0.21
clpC1 4040015 c.690G>A synonymous_variant 0.21
clpC1 4040021 c.684A>T synonymous_variant 0.23
clpC1 4040024 c.681A>G synonymous_variant 0.22
clpC1 4040027 c.678C>G synonymous_variant 0.21
clpC1 4040033 c.672G>C synonymous_variant 0.21
clpC1 4040042 c.663C>T synonymous_variant 0.19
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
embA 4244188 p.Thr319Ile missense_variant 0.12
embB 4246544 p.Thr11Pro missense_variant 0.14
embB 4246548 p.Pro12Gln missense_variant 0.17
embB 4246555 c.42G>C synonymous_variant 0.19
embB 4246556 p.Ala15Pro missense_variant 0.19
embB 4246563 p.Leu17Trp missense_variant 0.27
embB 4246567 c.54G>T synonymous_variant 0.25
embB 4247028 p.Leu172Arg missense_variant 0.35
embB 4249053 p.Thr847Ile missense_variant 0.12
aftB 4267647 p.Asp397Gly missense_variant 1.0
ethA 4326676 p.Ser266Arg missense_variant 0.97
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 1.0