TB-Profiler result

Run: SRR18003024
Summary

Run ID: SRR18003024

Sample name:

Date: 03-04-2023 19:14:27

Number of reads: 1205175

Percentage reads mapped: 31.54

Strain: lineage2.2.1

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 1.0
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 1.0
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.38 rifampicin
rpoB 761196 p.Leu464Met missense_variant 0.29 rifampicin
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.59 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.34 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.82 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.73 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5200 c.-40C>T upstream_gene_variant 0.18
gyrB 5494 c.255G>A synonymous_variant 0.14
gyrB 5554 c.315C>T synonymous_variant 0.15
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9169 p.Leu623Arg missense_variant 0.11
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490959 c.177C>T synonymous_variant 0.14
fgd1 491728 p.Asp316His missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575282 c.-66C>T upstream_gene_variant 1.0
mshA 575907 p.Ala187Val missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.43
mshA 576181 c.834G>A synonymous_variant 0.13
ccsA 620625 p.Ile245Met missense_variant 1.0
rpoB 761102 c.1296A>G synonymous_variant 0.36
rpoB 761132 c.1326G>T synonymous_variant 0.33
rpoB 761133 c.1327T>C synonymous_variant 0.36
rpoB 761147 c.1341C>T synonymous_variant 0.33
rpoB 761150 c.1344A>T synonymous_variant 0.33
rpoB 761156 c.1350G>C synonymous_variant 0.32
rpoB 761159 c.1353G>A synonymous_variant 0.33
rpoB 761165 c.1359G>C synonymous_variant 0.36
rpoB 761168 c.1362C>G synonymous_variant 0.26
rpoB 761180 c.1374A>C synonymous_variant 0.27
rpoB 761186 p.Glu460Asp missense_variant 0.29
rpoB 761192 c.1386C>A synonymous_variant 0.27
rpoB 761195 c.1389G>C synonymous_variant 0.29
rpoB 761201 c.1395G>A synonymous_variant 0.29
rpoB 761204 c.1398C>T synonymous_variant 0.25
rpoB 761207 c.1401C>A synonymous_variant 0.24
rpoB 761213 c.1407G>C synonymous_variant 0.24
rpoB 761219 c.1413G>C synonymous_variant 0.26
rpoB 761231 c.1425C>T synonymous_variant 0.19
rpoB 761234 c.1428G>T synonymous_variant 0.22
rpoB 761243 c.1437G>C synonymous_variant 0.17
rpoB 761246 c.1440C>T synonymous_variant 0.17
rpoB 762071 p.Asp755Glu missense_variant 0.13
rpoB 762080 c.2274G>C synonymous_variant 0.14
rpoB 762085 p.Ala760Glu missense_variant 0.15
rpoC 762947 c.-423C>G upstream_gene_variant 0.16
rpoC 762971 c.-399G>C upstream_gene_variant 0.21
rpoC 762980 c.-390T>C upstream_gene_variant 0.24
rpoC 762989 c.-381G>C upstream_gene_variant 0.24
rpoC 762995 c.-375G>C upstream_gene_variant 0.21
rpoB 763005 p.Cys1067Val missense_variant 0.2
rpoB 763014 p.Met1070Leu missense_variant 0.19
rpoB 763017 p.Gln1071Glu missense_variant 0.19
rpoC 763028 c.-342T>C upstream_gene_variant 0.18
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoB 763038 p.Thr1078Ala missense_variant 0.23
rpoC 763043 c.-327G>C upstream_gene_variant 0.23
rpoC 763053 c.-317T>C upstream_gene_variant 0.29
rpoC 763067 c.-303C>G upstream_gene_variant 0.14
rpoC 763070 c.-300T>C upstream_gene_variant 0.27
rpoB 763077 p.Val1091Thr missense_variant 0.23
rpoC 763103 c.-267G>C upstream_gene_variant 0.14
rpoC 763633 c.264T>C synonymous_variant 0.11
rpoC 763660 c.291T>G synonymous_variant 0.13
rpoC 763666 c.297G>C synonymous_variant 0.12
rpoC 763699 c.330G>T synonymous_variant 0.13
rpoC 763705 c.336G>C synonymous_variant 0.11
rpoC 763708 c.339G>C synonymous_variant 0.14
rpoC 763717 c.348T>C synonymous_variant 0.14
rpoC 764575 c.1206T>C synonymous_variant 0.13
rpoC 764581 c.1212T>C synonymous_variant 0.13
rpoC 764582 p.Leu405Met missense_variant 0.16
rpoC 764593 c.1224C>T synonymous_variant 0.16
rpoC 764602 c.1233C>G synonymous_variant 0.13
rpoC 764605 c.1236G>T synonymous_variant 0.2
rpoC 764611 c.1242G>T synonymous_variant 0.19
rpoC 764626 c.1257C>T synonymous_variant 0.17
rpoC 764632 c.1263T>C synonymous_variant 0.11
rpoC 764650 c.1281G>T synonymous_variant 0.2
rpoC 764653 c.1284G>C synonymous_variant 0.14
rpoC 764656 c.1287C>G synonymous_variant 0.14
rpoC 764665 c.1296C>T synonymous_variant 0.14
rpoC 764668 c.1299C>T synonymous_variant 0.14
rpoC 764677 c.1308C>G synonymous_variant 0.17
rpoC 764692 c.1323C>T synonymous_variant 0.14
rpoC 764706 p.Leu446Gln missense_variant 0.17
rpoC 766663 c.3294G>A synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776182 p.Asp767Asn missense_variant 1.0
mmpL5 777008 c.1473G>A synonymous_variant 0.13
mmpS5 778848 p.Ile20Val missense_variant 0.14
mmpS5 778860 p.Val16Phe missense_variant 0.14
mmpL5 779106 c.-626C>T upstream_gene_variant 0.15
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1305120 c.2190G>A synonymous_variant 0.15
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471845 n.-1G>A upstream_gene_variant 0.12
rrs 1471979 n.134T>C non_coding_transcript_exon_variant 0.25
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.33
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.33
rrs 1472080 n.235G>A non_coding_transcript_exon_variant 0.38
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.77
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.77
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.16
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.74
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.69
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.15
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.14
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.14
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.92
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.79
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.81
rrs 1472282 n.437T>G non_coding_transcript_exon_variant 0.48
rrs 1472284 n.439C>T non_coding_transcript_exon_variant 0.29
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.32
rrs 1472293 n.448C>A non_coding_transcript_exon_variant 0.3
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.43
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.4
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.4
rrs 1472332 n.487A>G non_coding_transcript_exon_variant 0.4
rrs 1472333 n.488G>A non_coding_transcript_exon_variant 0.43
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.46
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.47
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.5
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.5
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.38
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.43
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.5
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 0.29
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.33
rrs 1472436 n.591G>T non_coding_transcript_exon_variant 0.33
rrs 1472437 n.592T>G non_coding_transcript_exon_variant 0.33
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.38
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.38
rrs 1472449 n.604C>T non_coding_transcript_exon_variant 0.33
rrs 1472450 n.605A>C non_coding_transcript_exon_variant 0.33
rrs 1472451 n.606C>T non_coding_transcript_exon_variant 0.33
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 0.38
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.38
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.3
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.3
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.46
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.81
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.82
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.84
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.15
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.15
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.16
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.17
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.19
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.17
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.17
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.65
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.16
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.64
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.18
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.9
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.63
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.2
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.2
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.64
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.23
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.83
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.92
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.29
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.63
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.31
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.24
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.88
rrs 1472674 n.829T>G non_coding_transcript_exon_variant 0.59
rrs 1472675 n.830T>A non_coding_transcript_exon_variant 0.83
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.72
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.75
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.58
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.34
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.6
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.29
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.33
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.6
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.33
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.32
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.32
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.44
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.28
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.41
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.4
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.4
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.4
rrs 1472839 n.995A>T non_coding_transcript_exon_variant 0.15
rrs 1472842 n.997G>A non_coding_transcript_exon_variant 0.13
rrs 1472843 n.998A>T non_coding_transcript_exon_variant 0.13
rrs 1472849 n.1005delT non_coding_transcript_exon_variant 0.36
rrs 1472856 n.1012delA non_coding_transcript_exon_variant 0.29
rrs 1472861 n.1018dupT non_coding_transcript_exon_variant 0.27
rrs 1472874 n.1029C>T non_coding_transcript_exon_variant 0.27
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 0.27
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.41
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.76
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.78
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.78
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.89
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.87
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.86
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.8
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.8
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.89
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.93
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.93
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.93
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.92
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.91
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.91
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.9
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.88
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.9
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.9
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.9
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.82
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.88
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.91
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.9
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.91
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.91
rrs 1473270 n.1425G>A non_coding_transcript_exon_variant 0.72
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.9
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.87
rrs 1473305 n.1460G>T non_coding_transcript_exon_variant 0.69
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.86
rrl 1473816 n.159C>T non_coding_transcript_exon_variant 0.29
rrl 1474124 n.467G>C non_coding_transcript_exon_variant 0.65
rrl 1474125 n.468C>G non_coding_transcript_exon_variant 0.65
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.67
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.67
rrl 1474141 n.484G>C non_coding_transcript_exon_variant 0.67
rrl 1474142 n.485C>G non_coding_transcript_exon_variant 0.67
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.71
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 0.72
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.72
rrl 1474171 n.514C>T non_coding_transcript_exon_variant 0.72
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.81
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.84
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.62
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.82
rrl 1474199 n.542G>A non_coding_transcript_exon_variant 0.74
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 0.85
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.85
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.8
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.89
rrl 1474280 n.623C>T non_coding_transcript_exon_variant 0.77
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.61
rrl 1474282 n.625G>T non_coding_transcript_exon_variant 0.16
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.89
rrl 1474315 n.658A>G non_coding_transcript_exon_variant 0.16
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.6
rrl 1474317 n.660G>A non_coding_transcript_exon_variant 0.6
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.88
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.86
rrl 1474353 n.696A>T non_coding_transcript_exon_variant 0.83
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.84
rrl 1474355 n.698A>T non_coding_transcript_exon_variant 0.16
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.85
rrl 1474383 n.726G>T non_coding_transcript_exon_variant 0.59
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.64
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.47
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.66
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.74
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.65
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.65
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.65
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.62
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.77
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.13
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.71
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.68
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.8
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.68
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.71
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.12
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.78
rrl 1474584 n.927C>T non_coding_transcript_exon_variant 0.82
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.71
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.78
rrl 1474634 n.977T>C non_coding_transcript_exon_variant 0.12
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.92
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.93
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.93
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.77
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.73
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.95
rrl 1474694 n.1037C>T non_coding_transcript_exon_variant 0.71
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.22
rrl 1474723 n.1066G>A non_coding_transcript_exon_variant 0.59
rrl 1474734 n.1077G>A non_coding_transcript_exon_variant 0.89
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.78
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.59
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.82
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.49
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.58
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.86
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.7
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.83
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.14
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.82
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.67
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.87
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.84
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.74
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.81
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.81
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.81
rrl 1474883 n.1226T>C non_coding_transcript_exon_variant 0.69
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.78
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.62
rrl 1475565 n.1908G>A non_coding_transcript_exon_variant 0.33
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.18
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.76
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.81
rrl 1475686 n.2029C>G non_coding_transcript_exon_variant 0.12
rrl 1475696 n.2039T>C non_coding_transcript_exon_variant 0.14
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.91
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 0.14
rrl 1475715 n.2058G>C non_coding_transcript_exon_variant 0.13
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.77
rrl 1475751 n.2094C>T non_coding_transcript_exon_variant 0.91
rrl 1475752 n.2095C>T non_coding_transcript_exon_variant 0.76
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.79
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.67
rrl 1475765 n.2108A>T non_coding_transcript_exon_variant 0.86
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.89
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.76
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.18
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.78
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.8
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.92
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.12
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.12
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.92
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.92
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.2
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.93
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.91
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.91
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.91
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.84
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.91
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.9
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.89
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 0.84
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.89
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.84
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.88
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.88
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.87
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.81
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.75
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.77
rrl 1476040 n.2383C>T non_coding_transcript_exon_variant 0.81
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.76
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.76
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.81
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.18
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.33
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.33
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 0.63
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.53
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.19
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.23
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.67
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.19
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.87
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.22
rrl 1476196 n.2539C>A non_coding_transcript_exon_variant 0.19
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.87
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.86
rrl 1476204 n.2547C>A non_coding_transcript_exon_variant 0.2
rrl 1476210 n.2553G>T non_coding_transcript_exon_variant 0.17
rrl 1476211 n.2554G>T non_coding_transcript_exon_variant 0.19
rrl 1476212 n.2555T>C non_coding_transcript_exon_variant 0.19
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.85
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.6
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.84
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.74
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.17
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.73
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.16
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.18
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.76
rrl 1476253 n.2596A>G non_coding_transcript_exon_variant 0.72
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.73
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.17
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.93
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.24
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.67
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.15
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.82
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.82
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.82
rrl 1476297 n.2640C>A non_coding_transcript_exon_variant 0.78
rrl 1476299 n.2642C>G non_coding_transcript_exon_variant 0.64
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.64
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.82
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.16
rrl 1476308 n.2651G>C non_coding_transcript_exon_variant 0.65
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.86
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.82
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.17
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.24
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.63
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.28
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.3
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.32
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.65
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.35
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.33
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.6
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.36
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.35
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.3
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.98
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.97
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.73
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.98
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.97
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.82
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.12
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.93
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.93
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.91
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.92
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.89
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.9
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.83
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.14
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.4
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.71
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.71
rrl 1476586 n.2929C>T non_coding_transcript_exon_variant 0.38
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 0.62
rrl 1476603 n.2946G>T non_coding_transcript_exon_variant 0.56
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.53
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.53
rrl 1476613 n.2956G>A non_coding_transcript_exon_variant 0.5
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.56
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.56
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.5
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.56
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.56
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.47
rpsA 1833904 c.363G>A synonymous_variant 0.15
rpsA 1833949 c.408T>C synonymous_variant 0.19
rpsA 1833955 c.414G>T synonymous_variant 0.23
rpsA 1833970 c.429G>T synonymous_variant 0.33
rpsA 1833976 c.435C>T synonymous_variant 0.31
rpsA 1833979 c.438T>C synonymous_variant 0.41
rpsA 1833991 c.450C>A synonymous_variant 0.31
rpsA 1833994 c.453G>C synonymous_variant 0.39
rpsA 1833997 c.456G>C synonymous_variant 0.39
rpsA 1834000 c.459G>T synonymous_variant 0.27
rpsA 1834012 c.471G>C synonymous_variant 0.33
rpsA 1834015 c.474G>C synonymous_variant 0.39
rpsA 1834023 c.482_483insC frameshift_variant 0.26
rpsA 1834026 c.486delG frameshift_variant 0.25
rpsA 1834030 c.489C>T synonymous_variant 0.21
rpsA 1834039 c.498C>T synonymous_variant 0.27
rpsA 1834040 p.Lys167Gln missense_variant 0.33
rpsA 1834043 p.Glu168Gln missense_variant 0.26
rpsA 1834051 c.510G>A synonymous_variant 0.33
rpsA 1834054 c.513C>T synonymous_variant 0.27
rpsA 1834090 c.549G>T synonymous_variant 0.15
rpsA 1834177 c.636A>C synonymous_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154479 p.Val545Met missense_variant 0.13
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155592 p.Glu174Lys missense_variant 0.13
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223234 c.-70G>A upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ribD 2987008 p.Gly57Asp missense_variant 0.13
ribD 2987132 p.Met98Ile missense_variant 0.14
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087377 c.558C>T synonymous_variant 0.13
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568554 c.126G>A synonymous_variant 0.13
Rv3236c 3612813 p.Thr102Ala missense_variant 0.88
ddn 3987022 p.Arg60Gln missense_variant 0.14
clpC1 4039838 p.Leu289Ile missense_variant 0.17
clpC1 4039847 c.858C>T synonymous_variant 0.33
clpC1 4039850 c.855T>C synonymous_variant 0.33
clpC1 4039865 c.840T>C synonymous_variant 0.34
clpC1 4039873 p.Thr278Ser missense_variant 0.35
clpC1 4039875 p.Asn277Arg missense_variant 0.37
clpC1 4039877 c.828C>T synonymous_variant 0.28
clpC1 4039886 c.819C>G synonymous_variant 0.4
clpC1 4039889 c.816G>T synonymous_variant 0.36
clpC1 4039898 c.807C>G synonymous_variant 0.37
clpC1 4039904 c.801A>G synonymous_variant 0.49
clpC1 4039907 c.798G>A synonymous_variant 0.49
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.48
clpC1 4039934 c.771G>A synonymous_variant 0.47
clpC1 4039937 c.768G>C synonymous_variant 0.47
clpC1 4039943 c.762G>C synonymous_variant 0.45
clpC1 4039946 c.759A>C synonymous_variant 0.47
clpC1 4039952 c.753T>C synonymous_variant 0.45
clpC1 4039958 c.747G>C synonymous_variant 0.44
clpC1 4039964 c.741C>G synonymous_variant 0.43
clpC1 4039967 p.Gln246His missense_variant 0.44
clpC1 4039982 c.723G>C synonymous_variant 0.45
clpC1 4039985 c.720G>A synonymous_variant 0.44
clpC1 4039991 c.714G>C synonymous_variant 0.31
clpC1 4039994 p.Glu237Asp missense_variant 0.34
clpC1 4039997 c.708C>T synonymous_variant 0.35
clpC1 4040009 c.696C>T synonymous_variant 0.34
clpC1 4040015 c.690G>A synonymous_variant 0.34
clpC1 4040021 c.684A>C synonymous_variant 0.34
clpC1 4040024 c.681A>G synonymous_variant 0.34
clpC1 4040027 c.678C>G synonymous_variant 0.34
clpC1 4040033 c.672G>C synonymous_variant 0.31
clpC1 4040042 c.663C>T synonymous_variant 0.25
clpC1 4040048 c.657C>T synonymous_variant 0.19
clpC1 4040057 c.648C>T synonymous_variant 0.21
clpC1 4040060 c.645C>T synonymous_variant 0.18
clpC1 4040069 c.636G>C synonymous_variant 0.18
clpC1 4040087 c.618G>C synonymous_variant 0.18
clpC1 4040090 c.615T>C synonymous_variant 0.18
clpC1 4040096 c.609G>C synonymous_variant 0.18
clpC1 4040108 c.597G>C synonymous_variant 0.18
clpC1 4040111 c.594G>A synonymous_variant 0.19
clpC1 4040114 p.Ile197Met missense_variant 0.19
clpC1 4040117 c.588A>G synonymous_variant 0.19
clpC1 4040123 p.Glu194His missense_variant 0.19
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
embA 4244958 p.Ala576Thr missense_variant 0.13
aftB 4267647 p.Asp397Gly missense_variant 1.0
aftB 4267830 p.Gly336Asp missense_variant 0.22
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 1.0