TB-Profiler result

Run: ERR11465353
Summary

Run ID: ERR11465353

Sample name:

Date: 03-01-2024 03:17:34

Number of reads: 7219743

Percentage reads mapped: 88.74

Strain: lineage4.3.4.1

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Rifampicin
Isoniazid
Ethambutol
Pyrazinamide
Streptomycin
Fluoroquinolones
Moxifloxacin
Ofloxacin
Levofloxacin
Ciprofloxacin
Aminoglycosides
Amikacin
Capreomycin
Kanamycin
Cycloserine
Ethionamide
Clofazimine
Para-aminosalicylic_acid
Delamanid
Bedaquiline
Linezolid
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.4 Euro-American (LAM) LAM RD174 1.0
lineage4.3.4.1 Euro-American (LAM) LAM1;LAM2 RD174 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6592 c.-710C>G upstream_gene_variant 0.14
gyrA 6955 c.-347G>A upstream_gene_variant 0.15
gyrA 7129 c.-173T>G upstream_gene_variant 0.15
gyrA 7132 c.-170T>G upstream_gene_variant 0.15
gyrA 7136 c.-166T>C upstream_gene_variant 0.15
gyrA 7144 c.-158A>G upstream_gene_variant 0.16
gyrB 7145 p.Val636Ile missense_variant 0.16
gyrA 7153 c.-149G>C upstream_gene_variant 0.15
gyrA 7162 c.-140C>G upstream_gene_variant 0.16
gyrA 7165 c.-137C>G upstream_gene_variant 0.16
gyrA 7177 c.-125G>A upstream_gene_variant 0.17
gyrA 7178 c.-124T>C upstream_gene_variant 0.17
gyrA 7186 c.-116C>G upstream_gene_variant 0.18
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7415 c.114C>G synonymous_variant 0.16
gyrA 7418 c.117C>T synonymous_variant 0.17
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7601 c.300C>G synonymous_variant 0.19
gyrA 7607 c.306C>G synonymous_variant 0.22
gyrA 7631 c.330G>C synonymous_variant 0.27
gyrA 7637 c.336C>G synonymous_variant 0.27
gyrA 7652 c.351C>T synonymous_variant 0.23
gyrA 7658 c.357A>G synonymous_variant 0.24
gyrA 7664 c.363T>C synonymous_variant 0.2
gyrA 7667 c.366C>T synonymous_variant 0.2
gyrA 7670 c.369A>G synonymous_variant 0.21
gyrA 7676 c.375G>C synonymous_variant 0.2
gyrA 7679 c.378G>C synonymous_variant 0.2
gyrA 7683 c.382A>C synonymous_variant 0.21
gyrA 7694 c.393A>G synonymous_variant 0.23
gyrA 7697 c.396C>G synonymous_variant 0.23
gyrA 7715 c.414G>C synonymous_variant 0.16
gyrA 7727 c.426G>C synonymous_variant 0.17
gyrA 7728 c.427_429delAGGinsCGT synonymous_variant 0.17
gyrA 7763 c.462T>G synonymous_variant 0.28
gyrA 7784 c.483A>G synonymous_variant 0.26
gyrA 7787 c.486G>A synonymous_variant 0.25
gyrA 7793 c.492G>C synonymous_variant 0.26
gyrA 7799 c.498A>G synonymous_variant 0.24
gyrA 7802 c.501C>G synonymous_variant 0.24
gyrA 7814 c.513C>G synonymous_variant 0.23
gyrA 7823 c.522G>C synonymous_variant 0.2
gyrA 7835 c.534A>C synonymous_variant 0.18
gyrA 7841 c.540C>T synonymous_variant 0.15
gyrA 8609 c.1308G>C synonymous_variant 0.2
gyrA 8619 c.1318T>C synonymous_variant 0.19
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9317 c.2016G>C synonymous_variant 0.15
gyrA 9345 c.2044A>C synonymous_variant 0.14
gyrA 9353 c.2052G>C synonymous_variant 0.15
gyrA 9377 c.2076A>G synonymous_variant 0.15
gyrA 9383 c.2082T>C synonymous_variant 0.15
gyrA 9386 c.2085T>G synonymous_variant 0.14
mshA 575521 c.174A>G synonymous_variant 0.18
mshA 575527 c.180G>C synonymous_variant 0.22
mshA 575536 c.189T>C synonymous_variant 0.26
mshA 575539 c.192C>T synonymous_variant 0.26
mshA 575548 c.201C>T synonymous_variant 0.24
mshA 575561 p.Met72Val missense_variant 0.19
mshA 575569 c.222A>G synonymous_variant 0.19
mshA 575575 c.228G>A synonymous_variant 0.19
mshA 575582 p.Leu79Met missense_variant 0.18
mshA 575587 c.240C>G synonymous_variant 0.18
mshA 575590 c.243T>C synonymous_variant 0.18
mshA 575593 c.246G>C synonymous_variant 0.18
mshA 575597 p.Ile84Val missense_variant 0.18
mshA 575620 c.273G>C synonymous_variant 0.19
mshA 575627 p.Ala94Thr missense_variant 0.18
mshA 575635 c.288A>C synonymous_variant 0.17
mshA 575800 c.453G>T synonymous_variant 0.19
mshA 575803 c.456C>T synonymous_variant 0.18
mshA 575821 c.474G>C synonymous_variant 0.17
mshA 575833 c.486C>G synonymous_variant 0.15
mshA 575842 c.495G>C synonymous_variant 0.15
mshA 575864 c.517T>C synonymous_variant 0.17
mshA 575878 c.531A>G synonymous_variant 0.17
mshA 575884 c.537G>C synonymous_variant 0.16
mshA 575893 c.546C>G synonymous_variant 0.15
mshA 575965 c.618C>G synonymous_variant 0.15
ccsA 620625 c.735A>C synonymous_variant 0.15
ccsA 620631 c.741T>G synonymous_variant 0.17
ccsA 620649 c.759A>G synonymous_variant 0.24
ccsA 620676 c.786C>T synonymous_variant 0.34
ccsA 620694 c.804C>G synonymous_variant 0.35
ccsA 620698 p.Val270Ile missense_variant 0.35
ccsA 620712 c.822G>C synonymous_variant 0.33
ccsA 620718 c.828G>C synonymous_variant 0.33
ccsA 620721 c.831G>C synonymous_variant 0.32
ccsA 620733 c.843G>C synonymous_variant 0.34
ccsA 620739 c.849A>G synonymous_variant 0.28
ccsA 620742 c.852G>C synonymous_variant 0.27
ccsA 620748 c.858T>C synonymous_variant 0.27
ccsA 620778 c.888T>C synonymous_variant 0.21
ccsA 620783 p.Ala298Val missense_variant 0.22
ccsA 620796 c.906C>G synonymous_variant 0.2
ccsA 620802 c.912C>G synonymous_variant 0.15
rpoB 760130 p.Asp108Glu missense_variant 0.17
rpoB 760139 c.333A>G synonymous_variant 0.2
rpoB 760142 c.336C>G synonymous_variant 0.21
rpoB 760181 c.375T>C synonymous_variant 0.22
rpoB 760184 c.378A>G synonymous_variant 0.22
rpoB 760196 c.390C>G synonymous_variant 0.2
rpoB 760244 c.438G>C synonymous_variant 0.18
rpoB 760298 c.492G>C synonymous_variant 0.14
rpoB 760310 c.504G>C synonymous_variant 0.18
rpoB 760316 c.510C>G synonymous_variant 0.18
rpoB 760406 c.600G>C synonymous_variant 0.17
rpoB 760407 p.Ser201Gly missense_variant 0.17
rpoB 760415 c.609C>T synonymous_variant 0.19
rpoB 760424 c.618C>G synonymous_variant 0.2
rpoB 760430 c.624T>C synonymous_variant 0.19
rpoB 760454 c.648C>G synonymous_variant 0.14
rpoB 760496 c.690G>C synonymous_variant 0.16
rpoB 760502 c.696C>G synonymous_variant 0.17
rpoB 760541 c.735G>C synonymous_variant 0.15
rpoB 760547 c.741G>C synonymous_variant 0.17
rpoB 760563 p.Arg253Met missense_variant 0.2
rpoB 760568 c.762G>C synonymous_variant 0.21
rpoB 760574 c.768G>C synonymous_variant 0.2
rpoB 760591 p.Val262Ala missense_variant 0.3
rpoB 760611 c.805_807delTTGinsCTC synonymous_variant 0.37
rpoB 760625 c.819C>G synonymous_variant 0.39
rpoB 760646 c.840C>G synonymous_variant 0.37
rpoB 760655 c.849A>G synonymous_variant 0.37
rpoB 760661 c.855A>C synonymous_variant 0.32
rpoB 760670 c.864G>C synonymous_variant 0.33
rpoB 760674 c.868T>C synonymous_variant 0.32
rpoB 760679 c.873A>G synonymous_variant 0.3
rpoB 760683 c.877T>C synonymous_variant 0.3
rpoB 760724 c.918T>C synonymous_variant 0.23
rpoB 760730 c.924T>C synonymous_variant 0.26
rpoB 760796 c.990A>G synonymous_variant 0.16
rpoB 760805 c.999G>C synonymous_variant 0.17
rpoB 760808 c.1002C>G synonymous_variant 0.17
rpoB 760958 c.1152G>C synonymous_variant 0.14
rpoB 760979 c.1173G>A synonymous_variant 0.14
rpoB 760982 c.1176G>T synonymous_variant 0.15
rpoB 760985 c.1179G>C synonymous_variant 0.17
rpoB 760988 c.1182C>G synonymous_variant 0.17
rpoB 760991 c.1185G>T synonymous_variant 0.17
rpoB 760997 c.1191G>C synonymous_variant 0.17
rpoB 761015 c.1209G>C synonymous_variant 0.21
rpoB 761579 c.1773G>C synonymous_variant 0.17
rpoB 761645 c.1839C>G synonymous_variant 0.2
rpoB 761648 c.1842T>C synonymous_variant 0.21
rpoB 761666 c.1860G>C synonymous_variant 0.15
rpoB 761675 c.1869G>T synonymous_variant 0.18
rpoB 761690 c.1884G>C synonymous_variant 0.17
rpoB 761765 c.1959T>C synonymous_variant 0.16
rpoB 761772 p.His656Ala missense_variant 0.18
rpoB 761778 p.Asn658Asp missense_variant 0.16
rpoB 761792 c.1986T>C synonymous_variant 0.16
rpoB 761813 c.2007T>C synonymous_variant 0.26
rpoB 761834 c.2028T>C synonymous_variant 0.24
rpoB 761847 p.Cys681Arg missense_variant 0.23
rpoB 761852 c.2046C>G synonymous_variant 0.23
rpoB 761864 c.2058G>C synonymous_variant 0.24
rpoB 761868 p.Asp688Gln missense_variant 0.24
rpoB 761873 c.2067A>T synonymous_variant 0.24
rpoB 761882 c.2076C>G synonymous_variant 0.22
rpoB 761891 c.2085G>C synonymous_variant 0.19
rpoB 761892 p.Ile696Val missense_variant 0.19
rpoB 761903 c.2097T>C synonymous_variant 0.19
rpoB 761909 c.2103T>C synonymous_variant 0.16
rpoB 761912 c.2106T>C synonymous_variant 0.15
rpoB 761913 p.Asp703Gln missense_variant 0.15
rpoB 761916 p.Asp704Asn missense_variant 0.16
rpoB 761921 c.2115C>T synonymous_variant 0.15
rpoB 761930 c.2124G>C synonymous_variant 0.2
rpoB 761948 c.2142G>C synonymous_variant 0.22
rpoB 761954 c.2148C>G synonymous_variant 0.22
rpoB 762114 p.Ile770Val missense_variant 0.14
rpoC 763028 c.-342T>C upstream_gene_variant 0.18
rpoC 763031 c.-339T>C upstream_gene_variant 0.18
rpoC 763040 c.-330C>G upstream_gene_variant 0.23
rpoC 763058 c.-312C>G upstream_gene_variant 0.22
rpoC 763070 c.-300T>C upstream_gene_variant 0.26
rpoC 763076 c.-294C>G upstream_gene_variant 0.26
rpoC 763082 c.-288C>T upstream_gene_variant 0.26
rpoC 763103 c.-267G>C upstream_gene_variant 0.25
rpoC 763115 c.-255T>C upstream_gene_variant 0.23
rpoC 763127 c.-243G>C upstream_gene_variant 0.19
rpoC 763130 c.-240G>A upstream_gene_variant 0.17
rpoC 763160 c.-210G>T upstream_gene_variant 0.17
rpoC 763169 c.-201A>G upstream_gene_variant 0.15
rpoC 763741 c.372C>T synonymous_variant 0.15
rpoC 763744 c.375G>C synonymous_variant 0.14
rpoC 763921 c.552G>C synonymous_variant 0.16
rpoC 764227 c.858G>C synonymous_variant 0.16
rpoC 764239 c.870T>G synonymous_variant 0.16
rpoC 764242 c.873C>T synonymous_variant 0.16
rpoC 764245 c.876C>G synonymous_variant 0.16
rpoC 764254 c.885G>A synonymous_variant 0.21
rpoC 764263 c.894G>C synonymous_variant 0.22
rpoC 764266 c.897T>C synonymous_variant 0.22
rpoC 764278 c.909_912delACAGinsGACGAA frameshift_variant&missense_variant 0.22
rpoC 764283 c.916_917delGG frameshift_variant 0.22
rpoC 764320 c.951C>T synonymous_variant 0.37
rpoC 764338 c.969G>A synonymous_variant 0.36
rpoC 764353 c.984G>C synonymous_variant 0.33
rpoC 764365 c.996C>T synonymous_variant 0.17
rpoC 764387 c.1018T>C synonymous_variant 0.14
rpoC 764392 c.1023C>T synonymous_variant 0.14
rpoC 764575 c.1206T>G synonymous_variant 0.15
rpoC 764858 c.1489T>C synonymous_variant 0.14
rpoC 764869 c.1500C>T synonymous_variant 0.15
rpoC 764995 c.1626C>G synonymous_variant 0.92
rpoC 765826 c.2457T>C synonymous_variant 0.2
rpoC 765835 c.2466C>T synonymous_variant 0.21
rpoC 765871 c.2502T>G synonymous_variant 0.2
rpoC 765875 p.Val836Ile missense_variant 0.22
rpoC 765892 c.2523T>C synonymous_variant 0.24
rpoC 765904 c.2535C>G synonymous_variant 0.3
rpoC 765937 c.2568T>C synonymous_variant 0.28
rpoC 765946 c.2577C>T synonymous_variant 0.29
rpoC 765947 c.2578T>C synonymous_variant 0.28
rpoC 765961 c.2592G>T synonymous_variant 0.2
rpoC 765962 c.2593_2595delTTGinsCTT synonymous_variant 0.19
rpoC 765967 c.2598C>T synonymous_variant 0.21
rpoC 765982 c.2613C>T synonymous_variant 0.25
rpoC 765994 c.2625A>T synonymous_variant 0.25
rpoC 766003 c.2634G>C synonymous_variant 0.33
rpoC 766009 c.2640G>C synonymous_variant 0.27
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.27
rpoC 766021 c.2652G>C synonymous_variant 0.33
rpoC 766027 c.2658G>C synonymous_variant 0.39
rpoC 766043 p.Gln892Glu missense_variant 0.3
rpoC 766054 c.2685C>T synonymous_variant 0.24
rpoC 766061 p.Val898Asn missense_variant 0.23
rpoC 766067 p.Glu900Thr missense_variant 0.24
rpoC 766081 c.2712T>G synonymous_variant 0.23
rpoC 766084 c.2715A>T synonymous_variant 0.23
rpoC 766085 p.Pro906Ala missense_variant 0.23
rpoC 766108 c.2739C>T synonymous_variant 0.21
rpoC 766112 p.Tyr915His missense_variant 0.2
rpoC 766115 p.Ile916Val missense_variant 0.21
rpoC 766120 c.2751A>G synonymous_variant 0.21
rpoC 766129 c.2760C>G synonymous_variant 0.18
rpoC 766131 p.Tyr921Phe missense_variant 0.18
rpoC 766146 p.Gly926Ala missense_variant 0.19
rpoC 766164 p.Glu932Ala missense_variant 0.15
rpoC 766309 c.2940G>C synonymous_variant 0.17
rpoC 766315 c.2946C>G synonymous_variant 0.18
rpoC 766345 c.2976T>C synonymous_variant 0.28
rpoC 766348 c.2979A>G synonymous_variant 0.27
rpoC 766369 c.3000C>G synonymous_variant 0.33
rpoC 766381 c.3012C>T synonymous_variant 0.35
rpoC 766384 c.3015A>G synonymous_variant 0.35
rpoC 766393 c.3024C>G synonymous_variant 0.35
rpoC 766426 c.3057C>T synonymous_variant 0.45
rpoC 766429 c.3060C>G synonymous_variant 0.44
rpoC 766447 c.3078T>C synonymous_variant 0.47
rpoC 766459 c.3090G>C synonymous_variant 0.44
rpoC 766471 c.3102G>C synonymous_variant 0.4
rpoC 766480 c.3111C>T synonymous_variant 0.37
rpoC 766483 c.3114G>C synonymous_variant 0.36
rpoC 766486 c.3117A>G synonymous_variant 0.36
rpoC 766492 c.3123T>G synonymous_variant 0.36
rpoC 766493 p.Gly1042Asn missense_variant 0.35
rpoC 766516 c.3147C>G synonymous_variant 0.38
rpoC 766517 p.Thr1050Ser missense_variant 0.38
rpoC 766525 c.3156G>T synonymous_variant 0.36
rpoC 766528 c.3159T>G synonymous_variant 0.33
rpoC 766530 p.Arg1054Gln missense_variant 0.35
rpoC 766540 p.Asp1057Glu missense_variant 0.36
rpoC 766543 c.3174C>T synonymous_variant 0.36
rpoC 766549 c.3180G>C synonymous_variant 0.36
rpoC 766570 c.3201T>C synonymous_variant 0.39
rpoC 766573 c.3204T>G synonymous_variant 0.39
rpoC 766582 c.3213C>T synonymous_variant 0.38
rpoC 766585 c.3216T>C synonymous_variant 0.37
rpoC 766607 p.Ile1080Leu missense_variant 0.4
rpoC 766618 c.3249G>C synonymous_variant 0.41
rpoC 766624 c.3255G>C synonymous_variant 0.4
rpoC 766630 c.3261G>C synonymous_variant 0.4
rpoC 766634 p.Phe1089Ile missense_variant 0.39
rpoC 766645 c.3276A>G synonymous_variant 0.33
rpoC 766651 c.3282T>C synonymous_variant 0.29
rpoC 766652 c.3283_3284delTCinsAG synonymous_variant 0.28
rpoC 766658 p.Arg1097Gly missense_variant 0.28
rpoC 766666 c.3297C>G synonymous_variant 0.3
rpoC 766672 c.3303T>C synonymous_variant 0.31
rpoC 766678 c.3309C>T synonymous_variant 0.3
rpoC 766690 c.3321G>C synonymous_variant 0.35
rpoC 766694 p.Gln1109Asp missense_variant 0.34
rpoC 766708 c.3339A>G synonymous_variant 0.31
rpoC 766711 c.3342C>T synonymous_variant 0.28
rpoC 766720 c.3351C>T synonymous_variant 0.28
rpoC 766726 c.3357T>C synonymous_variant 0.27
rpoC 766732 c.3363G>C synonymous_variant 0.25
rpoC 766738 c.3369G>T synonymous_variant 0.23
rpoC 766747 c.3378C>T synonymous_variant 0.21
rpoC 766750 c.3381C>G synonymous_variant 0.21
rpoC 766753 c.3384C>T synonymous_variant 0.22
rpoC 766765 c.3396A>C synonymous_variant 0.25
rpoC 766774 c.3405T>C synonymous_variant 0.29
rpoC 766776 p.Arg1136His missense_variant 0.29
rpoC 766798 c.3429C>G synonymous_variant 0.21
rpoC 766801 c.3432C>T synonymous_variant 0.21
rpoC 766804 c.3435A>G synonymous_variant 0.21
rpoC 766807 c.3438T>C synonymous_variant 0.21
rpoC 766837 c.3468G>C synonymous_variant 0.25
rpoC 766843 c.3474T>C synonymous_variant 0.22
rpoC 766846 c.3477C>G synonymous_variant 0.21
rpoC 766858 c.3489C>T synonymous_variant 0.17
rpoC 766861 c.3492G>C synonymous_variant 0.14
rpoC 766864 c.3495G>C synonymous_variant 0.14
rpoC 766876 c.3507C>T synonymous_variant 0.15
rpoC 766894 c.3525T>C synonymous_variant 0.15
rpoC 766911 p.Ile1181Thr missense_variant 0.17
rpoC 766915 p.Asp1182Glu missense_variant 0.18
rpoC 766918 c.3549C>T synonymous_variant 0.18
rpoC 766921 c.3552G>C synonymous_variant 0.19
rpoC 766931 p.Ala1188Ser missense_variant 0.15
rpoC 766942 c.3573C>T synonymous_variant 0.15
rpoC 766945 c.3576A>C synonymous_variant 0.15
rpoC 766948 c.3579G>C synonymous_variant 0.16
rpoC 766978 c.3609C>A synonymous_variant 0.27
rpoC 766996 c.3627C>T synonymous_variant 0.28
rpoC 767008 c.3639G>A synonymous_variant 0.34
rpoC 767023 c.3654C>T synonymous_variant 0.27
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775916 c.2565T>G synonymous_variant 0.23
mmpL5 775975 p.Leu836Met missense_variant 0.19
mmpL5 776681 p.Leu600Ile missense_variant 0.18
mmpL5 776715 p.Lys589Pro missense_variant 0.24
mmpL5 777254 c.1227G>C synonymous_variant 0.16
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781628 c.69T>G synonymous_variant 0.16
rpsL 781652 c.93T>C synonymous_variant 0.22
rpsL 781655 c.96T>C synonymous_variant 0.24
rpsL 781658 c.99A>G synonymous_variant 0.26
rpsL 781676 c.117C>G synonymous_variant 0.31
rpsL 781682 c.123T>C synonymous_variant 0.32
rpsL 781709 c.150G>C synonymous_variant 0.33
rpsL 781715 c.156T>C synonymous_variant 0.34
rpsL 781718 c.159C>G synonymous_variant 0.34
rpsL 781728 c.169T>C synonymous_variant 0.32
rpsL 781733 c.174G>C synonymous_variant 0.3
rpsL 781736 c.177T>C synonymous_variant 0.29
rpsL 781748 c.189C>G synonymous_variant 0.29
rpsL 781751 c.192G>C synonymous_variant 0.29
rpsL 781754 c.195G>A synonymous_variant 0.28
rpsL 781760 c.201T>C synonymous_variant 0.29
rpsL 781766 c.207C>T synonymous_variant 0.31
rpsL 781808 c.249C>T synonymous_variant 0.24
rpsL 781811 c.252C>T synonymous_variant 0.23
rpsL 781814 c.255C>T synonymous_variant 0.23
rpsL 781817 c.258G>T synonymous_variant 0.22
rpsL 781829 c.270G>C synonymous_variant 0.19
rpsL 781832 c.273T>C synonymous_variant 0.18
rpsL 781835 c.276T>C synonymous_variant 0.19
rpsL 781841 c.282C>T synonymous_variant 0.21
rpsL 781865 c.306G>C synonymous_variant 0.17
rpsL 781868 c.309T>C synonymous_variant 0.16
rpsL 781871 c.312G>C synonymous_variant 0.18
rpsL 781877 c.318T>C synonymous_variant 0.19
rpsL 781889 c.330C>T synonymous_variant 0.19
rpsL 781892 c.333A>G synonymous_variant 0.19
rpsL 781895 c.336G>A synonymous_variant 0.18
rpsL 781898 c.339A>G synonymous_variant 0.19
rpsL 781907 c.348T>C synonymous_variant 0.24
rpsL 781916 c.357T>C synonymous_variant 0.26
rpsL 781929 p.Gly124Ser missense_variant 0.32
rplC 800612 c.-197A>G upstream_gene_variant 0.22
rplC 800618 c.-191T>C upstream_gene_variant 0.24
rplC 800633 c.-176T>C upstream_gene_variant 0.26
rplC 800654 c.-155T>C upstream_gene_variant 0.25
rplC 800693 c.-116A>T upstream_gene_variant 0.19
rplC 800720 c.-89T>C upstream_gene_variant 0.14
rplC 800738 c.-71T>C upstream_gene_variant 0.15
rplC 800753 c.-56C>T upstream_gene_variant 0.14
rplC 800780 c.-29C>G upstream_gene_variant 0.21
fbiC 1304661 c.1731C>T synonymous_variant 0.14
fbiC 1304724 c.1794A>G synonymous_variant 0.14
atpE 1461056 c.12T>A synonymous_variant 0.16
atpE 1461065 c.21C>T synonymous_variant 0.15
atpE 1461086 c.42A>C synonymous_variant 0.19
atpE 1461089 c.45G>C synonymous_variant 0.21
atpE 1461101 c.57T>C synonymous_variant 0.28
atpE 1461104 c.60C>T synonymous_variant 0.33
atpE 1461107 c.63C>G synonymous_variant 0.33
atpE 1461132 p.Val30Ile missense_variant 0.27
atpE 1461147 c.103_105delCTTinsTTG synonymous_variant 0.23
atpE 1461153 p.Ser37Ala missense_variant 0.22
atpE 1461159 p.Val39Ile missense_variant 0.2
atpE 1461167 c.123G>C synonymous_variant 0.18
atpE 1461170 c.126A>G synonymous_variant 0.18
atpE 1461179 c.135G>C synonymous_variant 0.15
atpE 1461182 c.138A>G synonymous_variant 0.15
atpE 1461185 c.141G>T synonymous_variant 0.14
atpE 1461188 c.144G>C synonymous_variant 0.15
atpE 1461197 c.153A>G synonymous_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.29
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.17
rrs 1472445 n.601_604delTCTC non_coding_transcript_exon_variant 0.4
rrs 1472451 n.606_607insCGGG non_coding_transcript_exon_variant 0.43
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 0.36
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.36
rrs 1472463 n.618G>C non_coding_transcript_exon_variant 0.38
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.38
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.44
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.2
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.24
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.21
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.18
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.24
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.17
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.19
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.16
rrl 1475202 n.1545G>A non_coding_transcript_exon_variant 0.33
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.33
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.33
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.32
rrl 1475232 n.1575A>G non_coding_transcript_exon_variant 0.23
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.17
rrl 1475297 n.1640C>T non_coding_transcript_exon_variant 0.22
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.22
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.32
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.42
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.48
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.57
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 0.57
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.46
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.31
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.31
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.3
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.27
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.27
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.27
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.27
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.33
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.56
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.45
rrl 1475989 n.2332T>A non_coding_transcript_exon_variant 0.44
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.44
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.29
rrl 1476032 n.2375C>G non_coding_transcript_exon_variant 0.27
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.27
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.28
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.26
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.26
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.26
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.26
rrl 1476088 n.2431A>T non_coding_transcript_exon_variant 0.36
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.32
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.3
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.3
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.3
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.3
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.31
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.2
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.2
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.22
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.2
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.19
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.17
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.19
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.19
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.22
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.24
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.28
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.26
inhA 1674471 c.270G>C synonymous_variant 0.15
inhA 1674474 c.273G>C synonymous_variant 0.16
inhA 1674480 c.279T>C synonymous_variant 0.16
inhA 1674486 c.285T>C synonymous_variant 0.25
inhA 1674489 c.288G>C synonymous_variant 0.25
inhA 1674507 c.306G>T synonymous_variant 0.34
inhA 1674542 p.Ala114Glu missense_variant 0.25
inhA 1674546 c.345T>C synonymous_variant 0.25
inhA 1674549 c.348G>C synonymous_variant 0.2
inhA 1674550 p.Ser117Ala missense_variant 0.21
inhA 1674585 c.384T>C synonymous_variant 0.17
inhA 1674589 p.Met130Leu missense_variant 0.17
inhA 1674604 c.403C>T synonymous_variant 0.17
inhA 1674656 p.Ser152Thr missense_variant 0.16
inhA 1674660 c.459G>C synonymous_variant 0.14
inhA 1674669 c.468G>C synonymous_variant 0.15
inhA 1674672 c.471C>G synonymous_variant 0.15
inhA 1674726 c.525G>C synonymous_variant 0.17
inhA 1674729 c.528G>T synonymous_variant 0.18
inhA 1674742 p.Lys181Gln missense_variant 0.25
inhA 1674746 p.Tyr182Phe missense_variant 0.25
inhA 1674756 c.555T>C synonymous_variant 0.26
inhA 1674762 c.561T>C synonymous_variant 0.3
inhA 1674780 c.579T>G synonymous_variant 0.26
inhA 1674801 c.600T>C synonymous_variant 0.25
inhA 1674816 c.615T>C synonymous_variant 0.19
inhA 1674819 c.618G>C synonymous_variant 0.19
inhA 1674825 c.624C>T synonymous_variant 0.19
inhA 1674828 p.Glu209Asp missense_variant 0.19
rpsA 1833724 c.183C>T synonymous_variant 0.15
rpsA 1833727 c.186G>C synonymous_variant 0.15
rpsA 1833733 c.192C>T synonymous_variant 0.15
rpsA 1833734 p.Ala65Ser missense_variant 0.15
rpsA 1833739 c.198C>T synonymous_variant 0.17
rpsA 1833742 c.201A>G synonymous_variant 0.17
rpsA 1833745 c.204G>C synonymous_variant 0.2
rpsA 1833772 c.231C>T synonymous_variant 0.32
rpsA 1833778 c.237C>T synonymous_variant 0.32
rpsA 1833781 c.240T>G synonymous_variant 0.32
rpsA 1833790 c.249T>C synonymous_variant 0.31
rpsA 1833799 c.258C>G synonymous_variant 0.29
rpsA 1833811 c.270G>C synonymous_variant 0.28
rpsA 1833829 c.288A>G synonymous_variant 0.23
rpsA 1833832 c.291G>A synonymous_variant 0.22
rpsA 1833838 c.297G>C synonymous_variant 0.2
rpsA 1833841 c.300C>G synonymous_variant 0.2
rpsA 1833847 c.306C>G synonymous_variant 0.24
rpsA 1833856 c.315A>G synonymous_variant 0.21
rpsA 1833862 c.321G>A synonymous_variant 0.19
rpsA 1833874 c.333T>C synonymous_variant 0.21
rpsA 1833892 c.351G>A synonymous_variant 0.21
rpsA 1833894 p.Ala118Glu missense_variant 0.22
rpsA 1833904 c.363G>A synonymous_variant 0.22
rpsA 1833928 c.387G>C synonymous_variant 0.14
rpsA 1833949 c.408T>C synonymous_variant 0.15
rpsA 1833994 c.453G>C synonymous_variant 0.17
rpsA 1834000 c.459G>C synonymous_variant 0.15
rpsA 1834114 c.573G>C synonymous_variant 0.15
rpsA 1834189 c.648G>C synonymous_variant 0.15
rpsA 1834345 c.804C>T synonymous_variant 0.16
rpsA 1834348 c.807T>C synonymous_variant 0.15
rpsA 1834619 c.1078T>C synonymous_variant 0.14
rpsA 1834633 c.1092A>G synonymous_variant 0.16
rpsA 1834639 c.1098T>C synonymous_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102269 c.774C>G synonymous_variant 0.18
PPE35 2169910 p.Asn235Tyr missense_variant 0.16
Rv1979c 2222854 p.Ile104Thr missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289061 p.Thr61Ala missense_variant 1.0
kasA 2517941 c.-174C>G upstream_gene_variant 0.24
kasA 2518843 c.729T>C synonymous_variant 0.17
kasA 2518847 p.Leu245Met missense_variant 0.18
kasA 2518853 p.Leu247Ile missense_variant 0.15
kasA 2519122 c.1008G>C synonymous_variant 0.15
kasA 2519224 c.1110C>A synonymous_variant 0.16
kasA 2519227 c.1113G>C synonymous_variant 0.15
thyX 3067661 c.285C>G synonymous_variant 0.15
thyX 3067685 c.261A>G synonymous_variant 0.15
thyX 3067688 c.258G>C synonymous_variant 0.15
thyX 3067694 c.252G>C synonymous_variant 0.15
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612009 p.Ala370Thr missense_variant 1.0
rpoA 3877638 c.870T>C synonymous_variant 0.15
rpoA 3877734 c.774G>C synonymous_variant 0.15
rpoA 3877764 c.744C>G synonymous_variant 0.17
rpoA 3877776 c.732T>C synonymous_variant 0.16
rpoA 3877782 c.726T>C synonymous_variant 0.17
rpoA 3877818 c.690A>G synonymous_variant 0.2
rpoA 3877848 c.660C>T synonymous_variant 0.33
rpoA 3877857 c.651G>A synonymous_variant 0.36
rpoA 3877875 c.633T>G synonymous_variant 0.43
rpoA 3877881 c.627G>C synonymous_variant 0.42
rpoA 3877884 c.624G>C synonymous_variant 0.41
rpoA 3877893 c.615C>T synonymous_variant 0.41
rpoA 3877900 p.Ser203Thr missense_variant 0.38
rpoA 3877905 c.603A>G synonymous_variant 0.36
rpoA 3877908 c.600T>C synonymous_variant 0.34
rpoA 3877920 c.588G>C synonymous_variant 0.33
rpoA 3877926 c.582G>C synonymous_variant 0.36
rpoA 3877962 c.546G>T synonymous_variant 0.28
rpoA 3877971 p.Asp179Glu missense_variant 0.21
rpoA 3878130 c.378C>G synonymous_variant 0.23
rpoA 3878142 p.Gly122Glu missense_variant 0.27
rpoA 3878163 c.345C>T synonymous_variant 0.31
rpoA 3878187 c.321C>G synonymous_variant 0.24
rpoA 3878193 c.315T>C synonymous_variant 0.22
rpoA 3878217 c.291A>G synonymous_variant 0.17
rpoA 3878271 c.237T>C synonymous_variant 0.15
rpoA 3878283 p.Glu75Asp missense_variant 0.15
clpC1 4038287 c.2418C>T synonymous_variant 0.95
clpC1 4038740 c.1965G>C synonymous_variant 0.15
clpC1 4039121 c.1584T>C synonymous_variant 0.17
clpC1 4039382 c.1323C>G synonymous_variant 0.15
clpC1 4039517 c.1188C>G synonymous_variant 0.19
clpC1 4039520 c.1185G>T synonymous_variant 0.18
clpC1 4039592 c.1113G>C synonymous_variant 0.21
clpC1 4039598 c.1107C>T synonymous_variant 0.29
clpC1 4039604 c.1101G>A synonymous_variant 0.3
clpC1 4039616 c.1089G>C synonymous_variant 0.32
clpC1 4039647 p.Glu353Ala missense_variant 0.42
clpC1 4039652 c.1053G>C synonymous_variant 0.42
clpC1 4039670 c.1035G>C synonymous_variant 0.41
clpC1 4039724 c.981A>G synonymous_variant 0.25
clpC1 4039730 c.975C>G synonymous_variant 0.15
clpC1 4039898 c.807C>G synonymous_variant 0.21
clpC1 4039904 c.801A>G synonymous_variant 0.14
clpC1 4039991 c.714G>A synonymous_variant 0.81
clpC1 4039994 p.Glu237Asp missense_variant 0.2
clpC1 4040291 c.414G>C synonymous_variant 0.22
clpC1 4040486 c.219G>A synonymous_variant 0.15
clpC1 4040522 c.183T>C synonymous_variant 0.17
clpC1 4040531 c.174T>C synonymous_variant 0.18
clpC1 4040540 c.165G>C synonymous_variant 0.16
clpC1 4040644 c.61A>C synonymous_variant 0.21
clpC1 4040648 c.57G>A synonymous_variant 0.19
clpC1 4040654 c.51G>A synonymous_variant 0.24
clpC1 4040657 c.48T>G synonymous_variant 0.24
clpC1 4040693 c.12A>T synonymous_variant 0.16
panD 4044162 c.120A>G synonymous_variant 0.2
embC 4240765 c.903C>G synonymous_variant 0.15
embC 4240780 c.918T>C synonymous_variant 0.14
embC 4240783 c.921G>C synonymous_variant 0.14
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4267574 c.1263G>C synonymous_variant 0.15
aftB 4267601 c.1236C>G synonymous_variant 0.16
aftB 4267625 c.1212T>C synonymous_variant 0.13
aftB 4267647 p.Asp397Ser missense_variant 0.2
aftB 4269075 c.-239T>C upstream_gene_variant 0.17
ubiA 4269087 p.Ala249Val missense_variant 0.16
aftB 4269096 c.-260C>G upstream_gene_variant 0.15
ubiA 4269099 c.727_735delTACAGCGGGinsGCGGGCGGCACC missense_variant&conservative_inframe_insertion 0.17
ubiA 4269109 p.Gly242Asp missense_variant 0.15
ubiA 4269117 p.Glu239Gly missense_variant 0.18
aftB 4269123 c.-287T>G upstream_gene_variant 0.18
aftB 4269132 c.-296G>C upstream_gene_variant 0.17
aftB 4269141 c.-307_-305delTTGinsCTC upstream_gene_variant 0.16
aftB 4269144 c.-308C>G upstream_gene_variant 0.17
ubiA 4269164 p.Leu224Met missense_variant 0.19
aftB 4269171 c.-335C>G upstream_gene_variant 0.17
aftB 4269183 c.-347T>C upstream_gene_variant 0.15
aftB 4269231 c.-395C>G upstream_gene_variant 0.14
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0