TB-Profiler result

Run: SRR20969475
Summary

Run ID: SRR20969475

Sample name:

Date: 2024-10-05T06:24:28.604554

Number of reads: 6199167

Percentage reads mapped: 66.46

Median coverage: 159.0

Strain: lineage1.2.1.2

Spoligotype:

Drug-resistance: Other

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage1.2.1.2 Indo-Oceanic RD239 1.0
lineage1 Indo-Oceanic RD239 0.99
lineage1.2.1 Indo-Oceanic RD239 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
n.799C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.31 streptomycin Uncertain significance Mutation from literature
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.58 streptomycin Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 6112 p.Met291Ile missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 8452 p.Ala384Val missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9260 c.1959G>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
Rv0010c 13175 c.384T>C synonymous_variant 1.0 isoniazid Not assoc w R
Rv0010c 13298 p.Ile87Met missense_variant 1.0 isoniazid Not assoc w R
Rv0010c 13460 c.99T>C synonymous_variant 1.0 isoniazid Not assoc w R
fgd1 491742 c.960T>C synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R
mshA 575368 c.21T>C synonymous_variant 1.0 isoniazid Not assoc w R
ethionamide Not assoc w R - Interim
Rv0565c 657578 c.-108T>C upstream_gene_variant 0.99 ethionamide
nusG 734116 c.-138T>C upstream_gene_variant 1.0 rifampicin Not assoc w R
rpoB 762149 c.2343G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762156 p.Val784Ile missense_variant 0.16 rifampicin
rpoB 762173 p.Glu789Asp missense_variant 0.22 rifampicin
rpoB 762176 c.2370T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762181 p.Asp792Ala missense_variant 0.22 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762197 c.2391C>G synonymous_variant 0.2 rifampicin
rpoB 762200 c.2394C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762266 c.2460T>C synonymous_variant 0.17 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 0.11 rifampicin Not assoc w R - Interim
rpoC 762932 c.-438G>T upstream_gene_variant 0.13 rifampicin
rpoC 762938 c.-432G>C upstream_gene_variant 0.17 rifampicin
rpoC 762944 c.-426C>T upstream_gene_variant 0.18 rifampicin
rpoB 762962 c.3156C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 762971 c.-399G>C upstream_gene_variant 0.22 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 0.22 rifampicin
rpoB 762995 c.3189G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 763005 p.Cys1067Val missense_variant 0.22 rifampicin
rpoC 763013 c.-357C>A upstream_gene_variant 0.23 rifampicin
rpoC 763022 c.-348C>A upstream_gene_variant 0.26 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.71 rifampicin Not assoc w R
rpoB 763053 c.3247T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 763074 p.Thr1090Val missense_variant 0.28 rifampicin
rpoB 763088 c.3282C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 763100 c.-270G>A upstream_gene_variant 0.21 rifampicin
rpoC 763103 c.-267G>C upstream_gene_variant 0.19 rifampicin
rpoB 763106 c.3300C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763109 c.-261C>T upstream_gene_variant 0.19 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 763118 p.Glu1104Asp missense_variant 0.19 rifampicin
rpoC 763121 c.-249C>T upstream_gene_variant 0.19 rifampicin
rpoC 763124 c.-246C>T upstream_gene_variant 0.19 rifampicin
rpoC 763127 c.-243G>A upstream_gene_variant 0.19 rifampicin
rpoB 763130 p.Glu1108Asp missense_variant 0.19 rifampicin
rpoC 763142 c.-228C>T upstream_gene_variant 0.19 rifampicin
rpoC 763148 c.-222G>C upstream_gene_variant 0.2 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.19 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.15 rifampicin
rpoC 763178 c.-192G>C upstream_gene_variant 0.13 rifampicin
rpoC 763462 c.93G>C synonymous_variant 0.13 rifampicin
rpoC 763468 c.99G>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 763471 c.102C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 763483 c.114G>C synonymous_variant 0.16 rifampicin
rpoC 763486 c.117T>G synonymous_variant 0.16 rifampicin
rpoC 763507 c.138G>C synonymous_variant 0.17 rifampicin
rpoC 763517 p.Lys50Arg missense_variant 0.18 rifampicin
rpoC 763528 c.159G>C synonymous_variant 0.18 rifampicin
rpoC 763531 c.162G>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 763534 c.165T>C synonymous_variant 0.18 rifampicin
rpoC 763537 c.168C>T synonymous_variant 0.17 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 763550 p.Tyr61Ala missense_variant 0.17 rifampicin
rpoC 763555 c.186C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763578 p.Phe70Tyr missense_variant 0.17 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 763609 c.240C>T synonymous_variant 0.12 rifampicin
rpoC 763884 p.Ala172Val missense_variant 1.0 rifampicin Not assoc w R
rpoC 763886 c.517C>A synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764470 c.1101C>G synonymous_variant 0.13 rifampicin
rpoC 764485 c.1116G>C synonymous_variant 0.19 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>T synonymous_variant 0.22 rifampicin
rpoC 764512 c.1143G>C synonymous_variant 0.2 rifampicin
rpoC 764518 c.1149C>T synonymous_variant 0.2 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764542 c.1173C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>C synonymous_variant 0.2 rifampicin
rpoC 764566 c.1197C>T synonymous_variant 0.2 rifampicin
rpoC 764572 c.1203G>T synonymous_variant 0.21 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>T synonymous_variant 0.22 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.23 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>C synonymous_variant 0.26 rifampicin
rpoC 764623 c.1254C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764635 c.1266C>G synonymous_variant 0.15 rifampicin
rpoC 764858 p.Leu497Met missense_variant 0.11 rifampicin
rpoC 764863 c.1494G>C synonymous_variant 0.12 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>G synonymous_variant 0.12 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.12 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.12 rifampicin Not assoc w R - Interim
rpoC 764896 c.1527C>T synonymous_variant 0.12 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.11 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.11 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.1 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.1 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 776100 p.Thr794Ile missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781793 c.234G>C synonymous_variant 0.13 streptomycin
rpsL 781799 c.240G>C synonymous_variant 0.13 streptomycin
rpsL 781802 c.243G>C synonymous_variant 0.13 streptomycin
rpsL 781805 c.246G>T synonymous_variant 0.13 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.14 streptomycin
rpsL 781829 c.270G>T synonymous_variant 0.14 streptomycin
rpsL 781838 c.279G>T synonymous_variant 0.14 streptomycin
rpsL 781841 c.282C>T synonymous_variant 0.14 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.14 streptomycin Not assoc w R - Interim
rpsL 781860 p.Ser101Ala missense_variant 0.14 streptomycin Uncertain significance
rpsL 781871 c.312G>C synonymous_variant 0.14 streptomycin
rpsL 781884 p.Asn109Asp missense_variant 0.14 streptomycin
rpsL 781889 c.330C>T synonymous_variant 0.14 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.14 streptomycin
rplC 800357 c.-452C>A upstream_gene_variant 1.0 linezolid Not assoc w R
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
isoniazid Not assoc w R
rifampicin Not assoc w R
embR 1417019 p.Cys110Tyr missense_variant 1.0 ethambutol Not assoc w R
embR 1417554 c.-207C>G upstream_gene_variant 0.99 ethambutol
embR 1417793 c.-446C>T upstream_gene_variant 1.0 ethambutol
atpE 1460907 c.-138T>C upstream_gene_variant 1.0 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.42 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.42 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471928 n.83T>G non_coding_transcript_exon_variant 0.41 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471930 n.85_89delGGAGAinsTTGCAGGG non_coding_transcript_exon_variant 0.43 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472069 n.224G>A non_coding_transcript_exon_variant 0.21 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.32 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.46 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.47 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472123 n.278A>G non_coding_transcript_exon_variant 0.56 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472150 n.305T>G non_coding_transcript_exon_variant 0.59 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.59 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.58 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472278 n.433C>T non_coding_transcript_exon_variant 0.32 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472279 n.434T>C non_coding_transcript_exon_variant 0.32 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.3 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.3 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.3 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.3 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472298 n.453G>C non_coding_transcript_exon_variant 0.31 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472299 n.455_459delCCGGG non_coding_transcript_exon_variant 0.32 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472309 n.464_470delCTCGGATinsG non_coding_transcript_exon_variant 0.32 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.31 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.31 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 0.31 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472330 n.485G>T non_coding_transcript_exon_variant 0.31 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.31 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.49 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.53 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 0.53 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472447 n.602C>T non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.55 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.55 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.56 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.58 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472485 n.640delGinsTA non_coding_transcript_exon_variant 0.6 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.61 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.63 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472504 n.659A>T non_coding_transcript_exon_variant 0.64 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472505 n.660G>A non_coding_transcript_exon_variant 0.64 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.65 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.56 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.53 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.52 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472574 n.729T>A non_coding_transcript_exon_variant 0.53 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.53 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.61 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.62 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.51 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.51 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472671 n.826G>A non_coding_transcript_exon_variant 0.46 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.45 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472674 n.829T>G non_coding_transcript_exon_variant 0.45 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.46 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472680 n.835C>T non_coding_transcript_exon_variant 0.46 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.45 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.46 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472685 n.840G>A non_coding_transcript_exon_variant 0.45 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472686 n.841G>C non_coding_transcript_exon_variant 0.45 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.45 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472689 n.844C>T non_coding_transcript_exon_variant 0.46 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.5 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.51 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.58 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 0.58 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472840 n.995A>C non_coding_transcript_exon_variant 0.4 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472844 n.999_1001delCGCinsTCG non_coding_transcript_exon_variant 0.53 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.53 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472859 n.1014_1016delGCGinsTCT non_coding_transcript_exon_variant 0.56 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472866 n.1023dupT non_coding_transcript_exon_variant 0.6 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472874 n.1029C>T non_coding_transcript_exon_variant 0.6 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 0.6 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.62 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.66 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.64 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125_1128delCGTAinsT non_coding_transcript_exon_variant 0.63 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472974 n.1129A>T non_coding_transcript_exon_variant 0.63 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472977 n.1133dupT non_coding_transcript_exon_variant 0.63 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.63 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.62 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.57 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473089 n.1244A>C non_coding_transcript_exon_variant 0.5 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473091 n.1246G>C non_coding_transcript_exon_variant 0.49 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473094 n.1249T>A non_coding_transcript_exon_variant 0.49 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473099 n.1254T>C non_coding_transcript_exon_variant 0.48 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.49 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.49 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.49 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.49 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.49 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473120 n.1275C>G non_coding_transcript_exon_variant 0.5 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.5 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473123 n.1278A>G non_coding_transcript_exon_variant 0.5 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473132 n.1287T>C non_coding_transcript_exon_variant 0.54 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473135 n.1290C>T non_coding_transcript_exon_variant 0.55 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.56 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.56 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473202 n.1357C>T non_coding_transcript_exon_variant 0.26 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.68 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.65 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.64 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473286 n.1441_1445delCCCTCinsACTT non_coding_transcript_exon_variant 0.64 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473292 n.1447G>T non_coding_transcript_exon_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473293 n.1448G>T non_coding_transcript_exon_variant 0.63 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.63 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473346 n.1501G>C non_coding_transcript_exon_variant 0.49 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473365 n.1520C>G non_coding_transcript_exon_variant 0.36 kanamycin
capreomycin
streptomycin
amikacin
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474182 n.525C>A non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1474183 n.526T>G non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.529delA non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid
rrl 1474199 n.542G>T non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1474202 n.545T>G non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474253 n.596A>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474286 n.629_651delCTCCTTTTCCTCTCCGGAGGAGGinsACTTTTT non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1474311 n.654_655insT non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 0.15 capreomycin
linezolid
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1474487 n.830G>T non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474517 n.860C>G non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1474527 n.870T>G non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474542 n.885A>C non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474732 n.1075A>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474784 n.1127C>T non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474798 n.1141C>G non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474825 n.1168G>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.63 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474921 n.1264C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.13 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.13 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475688 n.2031G>A non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
rrl 1475696 n.2039T>A non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rrl 1475699 n.2042delCinsTT non_coding_transcript_exon_variant 0.16 capreomycin
linezolid
rrl 1475703 n.2046A>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid
rrl 1475704 n.2047C>T non_coding_transcript_exon_variant 0.17 capreomycin
linezolid
rrl 1475713 n.2056C>T non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1475757 n.2101_2110delACCCGCAAGG non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1475769 n.2112_2113insAGTCTTTGACTGC non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.58 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476024 n.2368delG non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1476028 n.2371A>G non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid
rrl 1476031 n.2374C>G non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1476034 n.2377_2378delCGinsATC non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1476040 n.2383C>T non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476080 n.2423T>G non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1476085 n.2428G>A non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid
rrl 1476097 n.2440C>T non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476100 n.2443A>C non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1476116 n.2459A>G non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.63 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.61 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.61 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>A non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.71 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>A non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476307 n.2650A>T non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1476309 n.2652G>T non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.73 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.7 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476524 n.2867_2868delCAinsT non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1476535 n.2878G>A non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.44 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476592 n.2935G>A non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476605 n.2948C>T non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.3 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476624 n.2967T>A non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1834213 c.672G>C synonymous_variant 0.23 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.24 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.26 pyrazinamide
rpsA 1834246 c.705G>T synonymous_variant 0.26 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.26 pyrazinamide
rpsA 1834252 c.711C>T synonymous_variant 0.26 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.27 pyrazinamide
rpsA 1834285 c.744G>A synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
rpsA 1834288 c.747C>T synonymous_variant 0.25 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.25 pyrazinamide
rpsA 1834298 p.Gln253Thr missense_variant 0.26 pyrazinamide
rpsA 1834315 c.774C>A synonymous_variant 0.27 pyrazinamide
rpsA 1834321 c.780C>T synonymous_variant 0.26 pyrazinamide
rpsA 1834327 c.786G>T synonymous_variant 0.24 pyrazinamide
rpsA 1834330 c.789C>G synonymous_variant 0.24 pyrazinamide
rpsA 1834339 c.798C>T synonymous_variant 0.21 pyrazinamide
rpsA 1834340 p.Met267Leu missense_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834348 c.807T>C synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
rpsA 1834354 c.813G>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
rpsA 1834600 c.1059G>C synonymous_variant 0.1 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 0.11 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.11 pyrazinamide
rpsA 1834624 c.1083G>C synonymous_variant 0.11 pyrazinamide
rpsA 1834625 p.Leu362Val missense_variant 0.11 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.11 pyrazinamide
rpsA 1834636 c.1095C>G synonymous_variant 0.11 pyrazinamide
rpsA 1834637 p.Asn366Asp missense_variant 0.11 pyrazinamide
rpsA 1834669 c.1128G>C synonymous_variant 0.11 pyrazinamide
rpsA 1834689 p.Ser383Thr missense_variant 0.11 pyrazinamide
tsnR 1853974 c.369C>T synonymous_variant 1.0 linezolid Not assoc w R
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
bacA 2062922 p.Ile603Val missense_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
streptomycin Not assoc w R
amikacin Not assoc w R
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Not assoc w R
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Not assoc w R
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
kasA 2518132 c.18C>T synonymous_variant 0.99 isoniazid
kasA 2519048 p.Gly312Ser missense_variant 1.0 isoniazid
ahpC 2726051 c.-142G>A upstream_gene_variant 1.0 isoniazid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
fbiD 3339417 c.300A>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
Rv3083 3448714 p.Asp71His missense_variant 0.99 ethionamide Uncertain significance
whiB7 3568488 c.191delG frameshift_variant 1.0 kanamycin Uncertain significance
amikacin Uncertain significance
streptomycin Uncertain significance
whiB7 3568610 p.Asp24Tyr missense_variant 1.0 kanamycin
amikacin
streptomycin
lpqB 3624486 p.Asp142Gly missense_variant 1.0 rifampicin Not assoc w R
bedaquiline Uncertain significance
mtrB 3625065 p.Met517Leu missense_variant 1.0 rifampicin Not assoc w R
bedaquiline Uncertain significance
mtrB 3626632 c.-19A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
fbiA 3640557 c.15T>C synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
clpC1 4038740 c.1965G>C synonymous_variant 0.11 pyrazinamide
clpC1 4038743 p.Thr654Ala missense_variant 0.11 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 0.12 pyrazinamide
clpC1 4038761 c.1944C>T synonymous_variant 0.14 pyrazinamide
clpC1 4038764 c.1941C>T synonymous_variant 0.14 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 0.14 pyrazinamide
clpC1 4038776 c.1929G>A synonymous_variant 0.15 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.14 pyrazinamide
clpC1 4038791 c.1914G>C synonymous_variant 0.15 pyrazinamide
clpC1 4038795 p.Ser637Thr missense_variant 0.15 pyrazinamide
clpC1 4038803 c.1902C>T synonymous_variant 0.14 pyrazinamide
clpC1 4038811 p.Gln632Lys missense_variant 0.13 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.13 pyrazinamide
clpC1 4038815 c.1890G>T synonymous_variant 0.14 pyrazinamide
clpC1 4038836 c.1869G>T synonymous_variant 0.16 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.15 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.14 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.14 pyrazinamide Not assoc w R - Interim
clpC1 4038863 c.1842G>T synonymous_variant 0.14 pyrazinamide Not assoc w R - Interim
clpC1 4040517 p.Val63Ala missense_variant 0.99 pyrazinamide Not assoc w R - Interim
glpK 4138377 p.Val460Ala missense_variant 0.99 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
isoniazid Not assoc w R
streptomycin Not assoc w R
rifampicin Not assoc w R
ethambutol Not assoc w R
glpK 4138457 c.1299C>T synonymous_variant 0.99 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
embC 4240671 p.Thr270Ile missense_variant 1.0 ethambutol Not assoc w R
embC 4241042 p.Asn394Asp missense_variant 1.0 ethambutol Not assoc w R
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4243580 c.348G>A synonymous_variant 1.0 ethambutol Not assoc w R
embA 4244420 c.1188G>C synonymous_variant 0.99 ethambutol Not assoc w R
embA 4245969 p.Pro913Ser missense_variant 0.99 ethambutol Not assoc w R
embB 4247578 c.1065G>A synonymous_variant 0.99 ethambutol Not assoc w R
embB 4247646 p.Glu378Ala missense_variant 0.98 ethambutol Not assoc w R
ubiA 4269387 p.Glu149Asp missense_variant 1.0 ethambutol Not assoc w R
ubiA 4269606 c.228T>C synonymous_variant 1.0 ethambutol Not assoc w R
whiB6 4338361 p.Arg54Gln missense_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
whiB6 4338603 c.-82C>T upstream_gene_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
gid 4407588 c.615A>G synonymous_variant 1.0 streptomycin Not assoc w R
gid 4407873 c.330G>T synonymous_variant 1.0 streptomycin Not assoc w R