Run ID: SRR1196474
Sample name:
Date: 2024-10-04T02:18:18.257224
Number of reads: 476393
Percentage reads mapped: 46.5
Median coverage: 10.0
Strain: lineage3.1.1
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage3.1.1 | East-African-Indian | RD750 | 0.82 |
lineage3.1 | East-African-Indian | RD750 | 1.0 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | embB | p.Met306Ile | Assoc w R | |
pyrazinamide | ||||
streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.72 | streptomycin | Uncertain significance | Mutation from literature |
embB | 4247431 | p.Met306Ile | missense_variant | 0.58 | ethambutol | Assoc w R |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 30 | c.30C>G | synonymous_variant | 0.26 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 0.64 | isoniazid | Not assoc w R - Interim |
dnaA | 750 | c.750C>G | synonymous_variant | 0.58 | isoniazid | |
dnaA | 756 | c.756T>C | synonymous_variant | 0.58 | isoniazid | |
dnaA | 768 | c.768C>G | synonymous_variant | 0.44 | isoniazid | |
dnaA | 771 | c.771A>C | synonymous_variant | 0.47 | isoniazid | |
dnaA | 777 | c.777A>G | synonymous_variant | 0.47 | isoniazid | |
dnaA | 786 | c.786C>T | synonymous_variant | 0.5 | isoniazid | |
dnaA | 792 | c.792C>T | synonymous_variant | 0.47 | isoniazid | |
dnaA | 942 | c.942C>G | synonymous_variant | 0.47 | isoniazid | |
dnaA | 945 | c.945G>A | synonymous_variant | 0.47 | isoniazid | |
dnaA | 955 | c.955A>C | synonymous_variant | 0.4 | isoniazid | |
dnaA | 960 | c.960C>A | synonymous_variant | 0.4 | isoniazid | |
dnaA | 1008 | c.1008G>A | synonymous_variant | 0.38 | isoniazid | Not assoc w R - Interim |
dnaA | 1014 | c.1014C>G | synonymous_variant | 0.38 | isoniazid | |
gyrB | 5809 | c.570C>G | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5812 | c.573C>G | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5824 | c.585A>G | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5827 | c.588G>A | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5849 | c.610C>T | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6136 | c.897G>A | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 6139 | c.900G>C | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6238 | c.999G>A | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6248 | c.1009_1011delCTAinsTTG | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6256 | c.1017G>A | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6268 | c.1029C>G | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6289 | c.1050C>T | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7514 | c.213C>G | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7523 | c.222C>G | synonymous_variant | 0.43 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7532 | c.231T>G | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.33 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7547 | c.246C>T | synonymous_variant | 0.33 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 8135 | c.834C>G | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8156 | c.855T>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8168 | c.867A>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8198 | c.897T>C | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8225 | c.924T>C | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8237 | c.936A>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8247 | p.Ile316Val | missense_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 0.47 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8270 | c.969G>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8276 | c.975G>A | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8283 | p.Ile328Leu | missense_variant | 0.53 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8288 | c.987T>C | synonymous_variant | 0.53 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.59 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8330 | c.1029C>G | synonymous_variant | 0.53 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8339 | c.1038A>G | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8340 | p.Ala347Ser | missense_variant | 0.47 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.39 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8933 | c.1632G>C | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8939 | c.1638T>C | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8942 | c.1641G>C | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCTC | synonymous_variant | 0.71 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8966 | c.1665C>G | synonymous_variant | 0.55 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8967 | p.Ala556Arg | missense_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9119 | c.1818A>G | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9122 | c.1821C>G | synonymous_variant | 0.59 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9143 | c.1842T>C | synonymous_variant | 0.53 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9152 | c.1851C>T | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9153 | p.Thr618Glu | missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9158 | c.1857C>T | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9161 | c.1860C>G | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9182 | c.1881T>C | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9191 | c.1890G>C | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 0.57 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9204 | p.Ser635Thr | missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
Rv0010c | 13879 | c.-321T>C | upstream_gene_variant | 0.6 | isoniazid | |
Rv0010c | 13890 | c.-332T>C | upstream_gene_variant | 0.6 | isoniazid | |
Rv0010c | 13893 | c.-335T>G | upstream_gene_variant | 0.64 | isoniazid | |
Rv0010c | 13897 | c.-339C>T | upstream_gene_variant | 0.64 | isoniazid | |
Rv0010c | 13903 | c.-345A>G | upstream_gene_variant | 0.58 | isoniazid | |
Rv0010c | 13909 | c.-351G>C | upstream_gene_variant | 0.54 | isoniazid | |
fgd1 | 490848 | c.66A>G | synonymous_variant | 0.7 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fgd1 | 490851 | c.69A>T | synonymous_variant | 0.7 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491601 | c.819T>C | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491610 | c.828A>G | synonymous_variant | 0.58 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R | |||||
Rv0565c | 656448 | p.Ile341Val | missense_variant | 0.54 | ethionamide | |
Rv0565c | 656454 | c.1017G>C | synonymous_variant | 0.54 | ethionamide | |
Rv0565c | 656457 | c.1014T>C | synonymous_variant | 0.58 | ethionamide | |
Rv0565c | 656469 | c.1002T>C | synonymous_variant | 0.5 | ethionamide | |
Rv0565c | 656475 | c.996A>G | synonymous_variant | 0.53 | ethionamide | |
Rv0565c | 656484 | c.987T>C | synonymous_variant | 0.57 | ethionamide | |
Rv0565c | 656487 | c.984T>C | synonymous_variant | 0.57 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656493 | c.978C>G | synonymous_variant | 0.56 | ethionamide | |
Rv0565c | 656502 | c.969C>T | synonymous_variant | 0.5 | ethionamide | |
Rv0565c | 656511 | c.960T>C | synonymous_variant | 0.5 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657081 | c.390G>A | synonymous_variant | 0.91 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657300 | c.171C>G | synonymous_variant | 0.53 | ethionamide | |
Rv0565c | 657318 | c.153T>C | synonymous_variant | 0.5 | ethionamide | |
Rv0565c | 657324 | c.147C>G | synonymous_variant | 0.5 | ethionamide | |
hadA | 731732 | c.-198G>A | upstream_gene_variant | 0.38 | isoniazid | |
hadA | 731747 | c.-183T>C | upstream_gene_variant | 0.47 | isoniazid | |
hadA | 731774 | c.-156T>C | upstream_gene_variant | 0.6 | isoniazid | |
hadA | 731789 | c.-141A>G | upstream_gene_variant | 0.65 | isoniazid | |
hadA | 731792 | c.-138G>A | upstream_gene_variant | 0.68 | isoniazid | |
hadA | 731801 | c.-129C>G | upstream_gene_variant | 0.61 | isoniazid | |
hadA | 731816 | c.-114G>A | upstream_gene_variant | 0.67 | isoniazid | |
hadA | 732253 | c.324T>C | synonymous_variant | 0.47 | isoniazid | |
hadA | 732259 | c.330T>C | synonymous_variant | 0.53 | isoniazid | |
hadA | 732268 | c.339T>G | synonymous_variant | 0.53 | isoniazid | |
hadA | 732270 | p.Glu114Val | missense_variant | 0.53 | isoniazid | |
hadA | 732272 | p.Ala115Ser | missense_variant | 0.56 | isoniazid | |
hadA | 732295 | c.366G>C | synonymous_variant | 0.68 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 0.59 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.62 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.59 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 0.6 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 0.55 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.65 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.58 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.61 | isoniazid | |
nusG | 734421 | c.168A>G | synonymous_variant | 0.53 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 0.5 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 0.55 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.58 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.6 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.53 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
nusG | 734499 | c.246G>C | synonymous_variant | 0.53 | rifampicin | |
nusG | 734841 | c.588G>C | synonymous_variant | 0.62 | rifampicin | |
nusG | 734847 | c.594T>C | synonymous_variant | 0.62 | rifampicin | |
nusG | 734850 | c.597C>G | synonymous_variant | 0.62 | rifampicin | |
nusG | 734853 | c.600A>G | synonymous_variant | 0.57 | rifampicin | |
nusG | 734854 | c.601T>C | synonymous_variant | 0.57 | rifampicin | |
nusG | 734882 | p.Ala210Gly | missense_variant | 0.6 | rifampicin | |
nusG | 734886 | c.633A>G | synonymous_variant | 0.57 | rifampicin | |
rpoB | 760118 | c.312T>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.57 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.56 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.56 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.56 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.5 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.5 | rifampicin | |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.64 | rifampicin | |
rpoB | 760412 | c.606C>G | synonymous_variant | 0.68 | rifampicin | |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 760472 | c.666C>T | synonymous_variant | 0.52 | rifampicin | |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.71 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 760715 | c.909C>G | synonymous_variant | 0.7 | rifampicin | |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 761219 | c.1413G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 761306 | c.1500C>G | synonymous_variant | 0.57 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 761330 | c.1524G>C | synonymous_variant | 0.52 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 762008 | c.2202C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.48 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.62 | rifampicin | |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 762314 | c.2508C>T | synonymous_variant | 0.64 | rifampicin | |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.69 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.57 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.64 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.75 | rifampicin | |
rpoC | 762395 | c.-975G>C | upstream_gene_variant | 0.46 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.64 | rifampicin | |
rpoB | 762510 | p.Ala902Pro | missense_variant | 0.64 | rifampicin | Uncertain significance |
rpoC | 762521 | c.-849C>T | upstream_gene_variant | 0.64 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.55 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.55 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.55 | rifampicin | |
rpoC | 762551 | c.-819C>G | upstream_gene_variant | 0.46 | rifampicin | |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.67 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 763013 | c.-357C>G | upstream_gene_variant | 0.7 | rifampicin | |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 763067 | c.-303C>G | upstream_gene_variant | 0.75 | rifampicin | |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.58 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.52 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 763190 | c.-180C>T | upstream_gene_variant | 0.37 | rifampicin | |
rpoC | 763202 | c.-168A>G | upstream_gene_variant | 0.32 | rifampicin | |
rpoC | 763205 | c.-165G>C | upstream_gene_variant | 0.32 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 0.32 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.32 | rifampicin | |
rpoB | 763227 | c.3421C>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 763238 | c.3432T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763402 | c.33C>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.43 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.4 | rifampicin | |
rpoC | 763492 | c.123G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 763606 | c.237C>T | synonymous_variant | 0.52 | rifampicin | |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 763657 | c.288G>A | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.45 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.39 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.55 | rifampicin | |
rpoC | 763774 | c.405G>C | synonymous_variant | 0.6 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 763816 | c.447C>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 0.5 | rifampicin | |
rpoC | 763853 | p.Val162Ile | missense_variant | 0.41 | rifampicin | |
rpoC | 764059 | c.690G>T | synonymous_variant | 0.54 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.46 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764102 | p.Val245Ile | missense_variant | 0.5 | rifampicin | |
rpoC | 764112 | p.Tyr248Phe | missense_variant | 0.5 | rifampicin | |
rpoC | 764116 | c.747C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 764215 | c.846A>G | synonymous_variant | 0.62 | rifampicin | |
rpoC | 764236 | c.867G>A | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 764272 | c.903G>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764338 | c.969G>A | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 764353 | c.984G>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.55 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036A>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 764419 | c.1050C>G | synonymous_variant | 0.7 | rifampicin | |
rpoC | 764428 | c.1059G>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.69 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.69 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.69 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 764489 | c.1120C>T | synonymous_variant | 0.76 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 764510 | c.1141C>T | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.79 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoC | 764548 | c.1179G>A | synonymous_variant | 0.81 | rifampicin | |
rpoC | 764551 | c.1182G>C | synonymous_variant | 0.81 | rifampicin | |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.82 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
rpoC | 764593 | c.1224C>T | synonymous_variant | 0.73 | rifampicin | |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.67 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519T>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.64 | rifampicin | |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 765055 | c.1686C>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 765346 | c.1977C>G | synonymous_variant | 0.67 | rifampicin | |
rpoC | 765349 | c.1980T>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 765352 | c.1983G>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 765364 | c.1995G>A | synonymous_variant | 0.67 | rifampicin | |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.57 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 0.67 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.59 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 765529 | c.2160C>T | synonymous_variant | 0.55 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.47 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.75 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 765628 | c.2259G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.6 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>T | synonymous_variant | 0.55 | rifampicin | |
rpoC | 765751 | c.2382C>G | synonymous_variant | 0.5 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 0.5 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.5 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.42 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 765850 | c.2481G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.5 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.5 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 765937 | c.2568T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766390 | c.3021C>T | synonymous_variant | 0.4 | rifampicin | |
rpoC | 766393 | c.3024C>G | synonymous_variant | 0.4 | rifampicin | |
rpoC | 766408 | c.3039C>G | synonymous_variant | 0.41 | rifampicin | |
rpoC | 766411 | c.3042C>G | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.53 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.6 | rifampicin | |
rpoC | 766462 | c.3093G>C | synonymous_variant | 0.62 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766540 | p.Asp1057Glu | missense_variant | 0.75 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 0.64 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 766582 | c.3213C>G | synonymous_variant | 0.5 | rifampicin | |
rpoC | 766583 | p.Gly1072Ser | missense_variant | 0.5 | rifampicin | |
rpoC | 766591 | c.3222A>G | synonymous_variant | 0.5 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 766597 | c.3228C>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.5 | rifampicin | |
rpoC | 766630 | c.3261G>C | synonymous_variant | 0.6 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.62 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.62 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 766795 | c.3426C>T | synonymous_variant | 0.46 | rifampicin | |
rpoC | 766801 | c.3432C>G | synonymous_variant | 0.5 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.6 | rifampicin | |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.7 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.5 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.59 | rifampicin | |
rpoC | 767158 | c.3789T>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.71 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 767212 | c.3843G>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775966 | p.Ala839Ser | missense_variant | 0.56 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775975 | c.2506T>C | synonymous_variant | 0.6 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775981 | p.Leu834Met | missense_variant | 0.6 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 775997 | c.2484T>C | synonymous_variant | 0.64 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776000 | p.Leu827Phe | missense_variant | 0.64 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776009 | c.2472A>G | synonymous_variant | 0.6 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776678 | c.1803G>C | synonymous_variant | 0.41 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776693 | p.Val596Thr | missense_variant | 0.41 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776705 | c.1776C>T | synonymous_variant | 0.39 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776756 | p.Asp575Glu | missense_variant | 0.35 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777110 | c.1371T>G | synonymous_variant | 0.5 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777115 | p.Met456Leu | missense_variant | 0.5 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777116 | c.1365C>T | synonymous_variant | 0.5 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777133 | p.Val450Ile | missense_variant | 0.47 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777158 | c.1323C>G | synonymous_variant | 0.57 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777164 | c.1317C>G | synonymous_variant | 0.59 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777170 | c.1311T>C | synonymous_variant | 0.6 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777176 | p.Glu435Asp | missense_variant | 0.57 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777191 | c.1290C>G | synonymous_variant | 0.53 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 777194 | c.1287A>G | synonymous_variant | 0.5 | bedaquiline | |
clofazimine | ||||||
rpsL | 781649 | c.90T>C | synonymous_variant | 0.53 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.53 | streptomycin | |
rpsL | 781772 | c.213C>A | synonymous_variant | 0.5 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.61 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 0.56 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.68 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 0.7 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.74 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.74 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.72 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.68 | streptomycin | |
rpsL | 781877 | c.318T>C | synonymous_variant | 0.68 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.53 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.5 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.55 | streptomycin | Uncertain significance |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.56 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.6 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.75 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.73 | linezolid | |
rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.75 | linezolid | |
rplC | 800648 | c.-161A>T | upstream_gene_variant | 0.75 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.76 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.77 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.73 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.7 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.71 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.71 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.64 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.64 | linezolid | |
rplC | 800794 | c.-15A>G | upstream_gene_variant | 0.57 | linezolid | |
rplC | 800796 | c.-13A>G | upstream_gene_variant | 0.57 | linezolid | |
rplC | 800798 | c.-10_-9delGG | upstream_gene_variant | 0.59 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 0.58 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 0.56 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 0.63 | linezolid | |
rplC | 800865 | c.57A>G | synonymous_variant | 0.46 | linezolid | |
rplC | 800867 | p.Ser20Asn | missense_variant | 0.5 | linezolid | |
rplC | 801367 | p.Ala187Thr | missense_variant | 0.6 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 0.5 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 0.5 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 0.54 | linezolid | |
rplC | 801426 | c.618C>G | synonymous_variant | 0.54 | linezolid | |
rplC | 801427 | p.Met207Val | missense_variant | 0.54 | linezolid | |
rplC | 801438 | c.630T>C | synonymous_variant | 0.62 | linezolid | |
rplC | 801442 | p.Ile212Val | missense_variant | 0.54 | linezolid | |
fbiC | 1303534 | p.Ser202Ala | missense_variant | 0.4 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303539 | c.609G>C | synonymous_variant | 0.47 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.58 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.67 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303602 | c.672A>G | synonymous_variant | 0.67 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303605 | c.675C>G | synonymous_variant | 0.67 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303608 | c.678G>A | synonymous_variant | 0.73 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303614 | c.684C>T | synonymous_variant | 0.67 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303617 | c.687C>G | synonymous_variant | 0.67 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303761 | c.831T>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303785 | c.855G>C | synonymous_variant | 0.56 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303789 | p.Ile287Val | missense_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 0.59 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303845 | c.915C>G | synonymous_variant | 0.67 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.65 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.68 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.76 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303920 | c.990C>T | synonymous_variant | 0.82 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303944 | c.1014G>C | synonymous_variant | 0.6 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303947 | c.1017T>G | synonymous_variant | 0.6 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.6 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303953 | p.Asp341Glu | missense_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303954 | p.Glu342Gln | missense_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303961 | p.Arg344Leu | missense_variant | 0.55 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303971 | c.1041T>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303980 | c.1050G>A | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304748 | c.1818T>C | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.59 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304787 | c.1857T>G | synonymous_variant | 0.59 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.59 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.61 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.64 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304853 | c.1923C>T | synonymous_variant | 0.67 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.6 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304869 | c.1939C>T | synonymous_variant | 0.67 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304875 | p.Ile649Val | missense_variant | 0.6 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304883 | p.Glu651Asp | missense_variant | 0.62 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304891 | p.Ile654Thr | missense_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304983 | c.2053C>T | synonymous_variant | 0.53 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304995 | p.Leu689Met | missense_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305006 | c.2076A>G | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305012 | c.2082G>C | synonymous_variant | 0.54 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305015 | c.2085G>C | synonymous_variant | 0.58 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305021 | c.2091C>G | synonymous_variant | 0.58 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305030 | c.2100G>C | synonymous_variant | 0.58 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305033 | c.2103T>G | synonymous_variant | 0.5 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
atpE | 1461170 | c.126A>G | synonymous_variant | 0.52 | bedaquiline | |
atpE | 1461185 | c.141G>T | synonymous_variant | 0.58 | bedaquiline | |
atpE | 1461197 | c.153A>G | synonymous_variant | 0.59 | bedaquiline | |
atpE | 1461219 | c.175T>C | synonymous_variant | 0.53 | bedaquiline | |
atpE | 1461233 | c.189A>C | synonymous_variant | 0.54 | bedaquiline | |
atpE | 1461251 | c.207G>C | synonymous_variant | 0.48 | bedaquiline | |
atpE | 1461254 | c.210T>C | synonymous_variant | 0.5 | bedaquiline | |
rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 0.67 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 0.67 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 0.7 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.7 | kanamycin | |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 0.69 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.69 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.44 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.48 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.48 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.5 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.5 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.74 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.68 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.82 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.81 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.7 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrl | 1473668 | n.11C>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473677 | n.20C>G | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.5 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.54 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473945 | n.288T>A | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473946 | n.289A>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 0.57 | capreomycin | |
linezolid | ||||||
rrl | 1473987 | n.330G>A | non_coding_transcript_exon_variant | 0.59 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474093 | n.436G>T | non_coding_transcript_exon_variant | 0.6 | capreomycin | |
linezolid | ||||||
rrl | 1474099 | n.442G>A | non_coding_transcript_exon_variant | 0.57 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474291 | n.635_649delTTCCTCTCCGGAGGA | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.69 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 0.68 | capreomycin | |
linezolid | ||||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.66 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474904 | n.1247G>A | non_coding_transcript_exon_variant | 0.71 | capreomycin | |
linezolid | ||||||
rrl | 1474956 | n.1299C>T | non_coding_transcript_exon_variant | 0.85 | capreomycin | |
linezolid | ||||||
rrl | 1474960 | n.1303C>G | non_coding_transcript_exon_variant | 0.83 | capreomycin | |
linezolid | ||||||
rrl | 1474963 | n.1306G>T | non_coding_transcript_exon_variant | 0.83 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474964 | n.1307T>A | non_coding_transcript_exon_variant | 0.83 | capreomycin | |
linezolid | ||||||
rrl | 1474965 | n.1308G>C | non_coding_transcript_exon_variant | 0.77 | capreomycin | |
linezolid | ||||||
rrl | 1474970 | n.1313G>A | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1475006 | n.1349A>T | non_coding_transcript_exon_variant | 0.71 | capreomycin | |
linezolid | ||||||
rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 0.75 | capreomycin | |
linezolid | ||||||
rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
linezolid | ||||||
rrl | 1475266 | n.1609T>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475267 | n.1610G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475275 | n.1618C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475276 | n.1619T>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475313 | n.1656G>A | non_coding_transcript_exon_variant | 0.46 | capreomycin | |
linezolid | ||||||
rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.65 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
linezolid | ||||||
rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 0.66 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 0.66 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475436 | n.1779C>T | non_coding_transcript_exon_variant | 0.66 | capreomycin | |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.72 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.73 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.72 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.65 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.64 | capreomycin | |
linezolid | ||||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.7 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 0.7 | capreomycin | |
linezolid | ||||||
rrl | 1475761 | n.2104_2106delCGCinsGT | non_coding_transcript_exon_variant | 0.77 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 0.75 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.72 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.69 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476031 | n.2374C>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
linezolid | ||||||
rrl | 1476032 | n.2375C>A | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
linezolid | ||||||
rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476034 | n.2377C>A | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
linezolid | ||||||
rrl | 1476048 | n.2391G>A | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.69 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 0.69 | capreomycin | |
linezolid | ||||||
rrl | 1476095 | n.2438C>G | non_coding_transcript_exon_variant | 0.71 | capreomycin | |
linezolid | ||||||
rrl | 1476105 | n.2448_2449delGAinsT | non_coding_transcript_exon_variant | 0.64 | capreomycin | |
linezolid | ||||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476117 | n.2460G>C | non_coding_transcript_exon_variant | 0.66 | capreomycin | |
linezolid | ||||||
rrl | 1476214 | n.2557G>A | non_coding_transcript_exon_variant | 0.85 | capreomycin | |
linezolid | ||||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.85 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.87 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.59 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.64 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.66 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | |
linezolid | ||||||
rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.5 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.5 | capreomycin | |
linezolid | ||||||
rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1476733 | n.3076C>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
inhA | 1673667 | c.-535A>G | upstream_gene_variant | 0.6 | isoniazid | |
ethionamide | ||||||
inhA | 1673679 | c.-523T>G | upstream_gene_variant | 0.64 | isoniazid | |
ethionamide | ||||||
inhA | 1673685 | c.-517C>T | upstream_gene_variant | 0.58 | isoniazid | |
ethionamide | ||||||
inhA | 1673710 | c.-492C>A | upstream_gene_variant | 0.69 | isoniazid | |
ethionamide | ||||||
inhA | 1673716 | c.-486_-485delGCinsAA | upstream_gene_variant | 0.75 | isoniazid | |
ethionamide | ||||||
inhA | 1674537 | c.336C>G | synonymous_variant | 0.79 | isoniazid | |
ethionamide | ||||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 0.69 | isoniazid | |
ethionamide | ||||||
inhA | 1674546 | c.345T>C | synonymous_variant | 0.69 | isoniazid | |
ethionamide | ||||||
inhA | 1674549 | c.348G>C | synonymous_variant | 0.69 | isoniazid | |
ethionamide | ||||||
inhA | 1674552 | c.351C>G | synonymous_variant | 0.69 | isoniazid | |
ethionamide | ||||||
inhA | 1674555 | c.354G>A | synonymous_variant | 0.65 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674561 | c.360C>T | synonymous_variant | 0.55 | isoniazid | |
ethionamide | ||||||
inhA | 1674582 | c.381T>C | synonymous_variant | 0.5 | isoniazid | |
ethionamide | ||||||
inhA | 1674585 | c.384T>C | synonymous_variant | 0.47 | isoniazid | |
ethionamide | ||||||
inhA | 1674589 | p.Met130Leu | missense_variant | 0.42 | isoniazid | |
ethionamide | ||||||
inhA | 1674597 | c.396G>A | synonymous_variant | 0.48 | isoniazid | |
ethionamide | ||||||
inhA | 1674601 | p.Leu134Thr | missense_variant | 0.48 | isoniazid | |
ethionamide | ||||||
inhA | 1674624 | c.423A>C | synonymous_variant | 0.5 | isoniazid | |
ethionamide | ||||||
inhA | 1674630 | c.429C>G | synonymous_variant | 0.45 | isoniazid | |
ethionamide | ||||||
inhA | 1674660 | c.459G>C | synonymous_variant | 0.65 | isoniazid | |
ethionamide | ||||||
inhA | 1674672 | c.471C>G | synonymous_variant | 0.67 | isoniazid | |
ethionamide | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 0.62 | isoniazid | |
ethionamide | ||||||
inhA | 1674789 | c.588G>C | synonymous_variant | 0.38 | isoniazid | |
ethionamide | ||||||
inhA | 1674822 | c.621C>G | synonymous_variant | 0.5 | isoniazid | |
ethionamide | ||||||
inhA | 1674828 | c.627G>A | synonymous_variant | 0.46 | isoniazid | |
ethionamide | ||||||
inhA | 1674846 | p.Ile215Met | missense_variant | 0.64 | isoniazid | |
ethionamide | ||||||
inhA | 1674864 | c.663C>T | synonymous_variant | 0.54 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674879 | c.678T>C | synonymous_variant | 0.62 | isoniazid | |
ethionamide | ||||||
inhA | 1674900 | c.699G>A | synonymous_variant | 0.56 | isoniazid | |
ethionamide | ||||||
inhA | 1674903 | c.702T>C | synonymous_variant | 0.5 | isoniazid | |
ethionamide | ||||||
inhA | 1674904 | p.Ala235Pro | missense_variant | 0.5 | isoniazid | |
ethionamide | ||||||
inhA | 1674909 | c.708G>A | synonymous_variant | 0.5 | isoniazid | |
ethionamide | ||||||
inhA | 1674942 | c.741T>G | synonymous_variant | 0.44 | isoniazid | |
ethionamide | ||||||
rpsA | 1833532 | c.-10A>C | upstream_gene_variant | 0.55 | pyrazinamide | |
rpsA | 1833554 | p.Thr5Ala | missense_variant | 0.62 | pyrazinamide | Uncertain significance |
rpsA | 1833568 | c.27G>C | synonymous_variant | 0.75 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.72 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.7 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.72 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.67 | pyrazinamide | |
rpsA | 1833721 | c.180A>G | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1833748 | c.207C>G | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.56 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.6 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.64 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.62 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.74 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.61 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.65 | pyrazinamide | |
rpsA | 1833971 | c.430C>T | synonymous_variant | 0.55 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.64 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.7 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.68 | pyrazinamide | |
rpsA | 1834210 | c.669C>T | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.56 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834264 | c.723G>C | synonymous_variant | 0.61 | pyrazinamide | |
rpsA | 1834303 | c.762T>C | synonymous_variant | 0.62 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.62 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.69 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.64 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834378 | c.837T>C | synonymous_variant | 0.69 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.71 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.56 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.6 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.65 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.67 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.64 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.62 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.62 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.67 | pyrazinamide | |
rpsA | 1834510 | c.969C>T | synonymous_variant | 0.75 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834513 | c.972C>G | synonymous_variant | 0.82 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.71 | pyrazinamide | |
rpsA | 1834540 | c.999G>C | synonymous_variant | 0.67 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.67 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.64 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.67 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.67 | pyrazinamide | |
rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.65 | pyrazinamide | |
rpsA | 1834684 | c.1143C>T | synonymous_variant | 0.65 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.65 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.7 | pyrazinamide | |
rpsA | 1834765 | p.Glu408Asp | missense_variant | 0.64 | pyrazinamide | |
rpsA | 1834775 | p.Ala412Thr | missense_variant | 0.6 | pyrazinamide | |
rpsA | 1834780 | c.1239A>G | synonymous_variant | 0.6 | pyrazinamide | |
rpsA | 1834786 | c.1245A>G | synonymous_variant | 0.6 | pyrazinamide | |
rpsA | 1834789 | c.1248T>C | synonymous_variant | 0.56 | pyrazinamide | |
rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.6 | pyrazinamide | |
tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.64 | linezolid | |
tsnR | 1853447 | c.-159C>G | upstream_gene_variant | 0.8 | linezolid | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
katG | 2155691 | c.421T>C | synonymous_variant | 0.64 | isoniazid | |
katG | 2155695 | c.417C>G | synonymous_variant | 0.64 | isoniazid | |
katG | 2155704 | c.408C>G | synonymous_variant | 0.58 | isoniazid | |
katG | 2155716 | c.396T>G | synonymous_variant | 0.69 | isoniazid | |
katG | 2155722 | c.390G>C | synonymous_variant | 0.69 | isoniazid | |
katG | 2155728 | c.384G>C | synonymous_variant | 0.64 | isoniazid | |
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.42 | isoniazid | |
kasA | 2518459 | c.345T>C | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518462 | c.348A>C | synonymous_variant | 0.47 | isoniazid | |
kasA | 2518468 | c.354A>C | synonymous_variant | 0.56 | isoniazid | |
kasA | 2518474 | c.360G>A | synonymous_variant | 0.58 | isoniazid | |
kasA | 2518480 | c.366T>C | synonymous_variant | 0.58 | isoniazid | |
kasA | 2518483 | c.369C>G | synonymous_variant | 0.61 | isoniazid | |
kasA | 2518504 | c.390T>C | synonymous_variant | 0.52 | isoniazid | |
kasA | 2518506 | p.Ala131Glu | missense_variant | 0.5 | isoniazid | |
kasA | 2518519 | c.405G>C | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518528 | c.414C>G | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518540 | c.426T>C | synonymous_variant | 0.57 | isoniazid | |
kasA | 2518768 | c.654C>T | synonymous_variant | 0.73 | isoniazid | |
kasA | 2518777 | c.663C>T | synonymous_variant | 0.79 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.85 | isoniazid | |
kasA | 2518789 | c.675G>C | synonymous_variant | 0.85 | isoniazid | |
kasA | 2518792 | c.678C>A | synonymous_variant | 0.86 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.81 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.71 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.73 | isoniazid | |
kasA | 2518879 | c.765A>G | synonymous_variant | 0.53 | isoniazid | |
kasA | 2518885 | c.771T>C | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518898 | c.784T>C | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518906 | c.792A>G | synonymous_variant | 0.46 | isoniazid | |
kasA | 2519068 | c.954C>T | synonymous_variant | 0.67 | isoniazid | |
kasA | 2519072 | p.Ala320Thr | missense_variant | 0.64 | isoniazid | |
kasA | 2519107 | c.993T>C | synonymous_variant | 0.92 | isoniazid | |
kasA | 2519108 | p.Asp332Gln | missense_variant | 0.85 | isoniazid | |
kasA | 2519122 | c.1008G>C | synonymous_variant | 0.88 | isoniazid | |
kasA | 2519137 | c.1023T>G | synonymous_variant | 0.86 | isoniazid | |
kasA | 2519158 | c.1044C>T | synonymous_variant | 0.8 | isoniazid | |
kasA | 2519167 | c.1053T>G | synonymous_variant | 0.8 | isoniazid | |
kasA | 2519173 | c.1059C>G | synonymous_variant | 0.75 | isoniazid | |
ahpC | 2726105 | c.-88G>A | upstream_gene_variant | 1.0 | isoniazid | Not assoc w R |
ahpC | 2726303 | c.111T>C | synonymous_variant | 0.64 | isoniazid | |
ahpC | 2726311 | p.Ser40Asn | missense_variant | 0.64 | isoniazid | |
ahpC | 2726336 | c.144G>C | synonymous_variant | 0.46 | isoniazid | |
ahpC | 2726348 | c.156T>C | synonymous_variant | 0.6 | isoniazid | |
folC | 2746375 | c.1224G>C | synonymous_variant | 0.46 | para-aminosalicylic_acid | |
folC | 2746390 | c.1209G>C | synonymous_variant | 0.4 | para-aminosalicylic_acid | |
folC | 2746393 | c.1206C>G | synonymous_variant | 0.43 | para-aminosalicylic_acid | |
folC | 2746401 | p.Ser400Ala | missense_variant | 0.55 | para-aminosalicylic_acid | |
folC | 2746402 | c.1197T>C | synonymous_variant | 0.55 | para-aminosalicylic_acid | |
folC | 2746414 | p.Glu395Gln | missense_variant | 0.46 | para-aminosalicylic_acid | |
folC | 2746420 | c.1179A>C | synonymous_variant | 0.46 | para-aminosalicylic_acid | |
folC | 2746426 | c.1173G>C | synonymous_variant | 0.46 | para-aminosalicylic_acid | |
folC | 2746438 | c.1161G>C | synonymous_variant | 0.46 | para-aminosalicylic_acid | |
folC | 2746451 | p.Gly383Ala | missense_variant | 0.5 | para-aminosalicylic_acid | |
folC | 2747071 | c.528C>G | synonymous_variant | 0.58 | para-aminosalicylic_acid | |
folC | 2747086 | c.513A>C | synonymous_variant | 0.64 | para-aminosalicylic_acid | |
folC | 2747089 | c.510G>C | synonymous_variant | 0.58 | para-aminosalicylic_acid | |
folC | 2747101 | c.498G>C | synonymous_variant | 0.58 | para-aminosalicylic_acid | |
Rv2477c | 2782483 | c.1560G>C | synonymous_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782498 | c.1545C>T | synonymous_variant | 0.6 | kanamycin | Not assoc w R |
levofloxacin | Not assoc w R | |||||
moxifloxacin | Not assoc w R | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
Rv2477c | 2782513 | c.1530G>T | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782522 | c.1521G>C | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782528 | c.1515G>C | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782537 | c.1506T>G | synonymous_variant | 0.53 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782540 | c.1503T>C | synonymous_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782546 | c.1497C>G | synonymous_variant | 0.43 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782927 | p.Thr372Glu | missense_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782930 | c.1113G>A | synonymous_variant | 0.53 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782936 | c.1107G>T | synonymous_variant | 0.56 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 0.39 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782966 | c.1077C>A | synonymous_variant | 0.45 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 0.45 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782972 | c.1071G>C | synonymous_variant | 0.45 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 0.45 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 0.43 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.75 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.73 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783098 | c.945C>G | synonymous_variant | 0.77 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783101 | c.942G>T | synonymous_variant | 0.77 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783107 | c.936G>A | synonymous_variant | 0.77 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.77 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783140 | c.903C>G | synonymous_variant | 0.8 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783149 | c.894G>C | synonymous_variant | 0.81 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783158 | c.885A>C | synonymous_variant | 0.82 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783182 | c.861C>G | synonymous_variant | 0.84 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783185 | c.858G>A | synonymous_variant | 0.83 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.83 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783221 | c.822G>C | synonymous_variant | 0.82 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783224 | c.819C>G | synonymous_variant | 0.8 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783230 | c.813T>G | synonymous_variant | 0.75 | kanamycin | |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783235 | c.808T>C | synonymous_variant | 0.79 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783254 | c.789A>G | synonymous_variant | 0.71 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783263 | c.780G>C | synonymous_variant | 0.67 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.62 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.56 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.44 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.64 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783718 | c.325T>C | synonymous_variant | 0.68 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 0.71 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.7 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.7 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.7 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783766 | p.Met93Leu | missense_variant | 0.7 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783776 | c.267G>C | synonymous_variant | 0.65 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783779 | c.264T>C | synonymous_variant | 0.65 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 0.62 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783883 | c.160T>C | synonymous_variant | 0.75 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783884 | c.159T>C | synonymous_variant | 0.75 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783887 | c.156C>G | synonymous_variant | 0.81 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783914 | c.129T>C | synonymous_variant | 0.95 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783920 | c.123G>C | synonymous_variant | 0.95 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783929 | c.114C>G | synonymous_variant | 0.95 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783932 | c.111C>T | synonymous_variant | 0.96 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783938 | c.105T>C | synonymous_variant | 0.78 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783953 | c.90G>A | synonymous_variant | 0.8 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783962 | c.81T>C | synonymous_variant | 0.76 | kanamycin | Not assoc w R - Interim |
levofloxacin | ||||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783971 | c.72G>C | synonymous_variant | 0.82 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783980 | c.63C>G | synonymous_variant | 0.82 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783992 | c.51T>C | synonymous_variant | 0.76 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2784405 | c.-363T>C | upstream_gene_variant | 0.47 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784428 | c.-386T>C | upstream_gene_variant | 0.47 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784429 | c.-387A>G | upstream_gene_variant | 0.47 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784432 | c.-390A>C | upstream_gene_variant | 0.47 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784435 | c.-393C>G | upstream_gene_variant | 0.47 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784452 | c.-410C>T | upstream_gene_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784454 | c.-412G>A | upstream_gene_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784456 | c.-414A>C | upstream_gene_variant | 0.5 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784472 | c.-430C>A | upstream_gene_variant | 0.43 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784477 | c.-435T>C | upstream_gene_variant | 0.43 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2752c | 3066009 | c.183G>C | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066018 | c.174T>C | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066330 | c.-139G>C | upstream_gene_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066335 | c.-144T>C | upstream_gene_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066339 | c.-148G>C | upstream_gene_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
thyX | 3067313 | c.633G>T | synonymous_variant | 0.53 | para-aminosalicylic_acid | |
thyX | 3067316 | c.630A>G | synonymous_variant | 0.53 | para-aminosalicylic_acid | |
thyX | 3067325 | c.621A>G | synonymous_variant | 0.53 | para-aminosalicylic_acid | |
thyX | 3067349 | c.597G>C | synonymous_variant | 0.54 | para-aminosalicylic_acid | |
thyX | 3067355 | c.591A>C | synonymous_variant | 0.57 | para-aminosalicylic_acid | |
thyX | 3067367 | c.579G>C | synonymous_variant | 0.62 | para-aminosalicylic_acid | |
thyX | 3067373 | c.573C>G | synonymous_variant | 0.6 | para-aminosalicylic_acid | |
thyX | 3067391 | c.555G>C | synonymous_variant | 0.69 | para-aminosalicylic_acid | |
thyX | 3067394 | c.552G>C | synonymous_variant | 0.62 | para-aminosalicylic_acid | |
thyX | 3067457 | c.489C>G | synonymous_variant | 0.54 | para-aminosalicylic_acid | |
thyX | 3067462 | c.484C>T | synonymous_variant | 0.47 | para-aminosalicylic_acid | |
thyX | 3067465 | p.Ile161Val | missense_variant | 0.47 | para-aminosalicylic_acid | |
thyX | 3067466 | c.480G>C | synonymous_variant | 0.47 | para-aminosalicylic_acid | |
thyX | 3067510 | c.436C>T | synonymous_variant | 0.54 | para-aminosalicylic_acid | |
thyX | 3067515 | p.Ser144Thr | missense_variant | 0.54 | para-aminosalicylic_acid | |
thyX | 3067611 | p.Lys112Thr | missense_variant | 0.53 | para-aminosalicylic_acid | |
thyX | 3067619 | c.327A>C | synonymous_variant | 0.57 | para-aminosalicylic_acid | |
thyX | 3067631 | c.315C>G | synonymous_variant | 0.56 | para-aminosalicylic_acid | |
thyX | 3067634 | c.312C>G | synonymous_variant | 0.56 | para-aminosalicylic_acid | |
thyX | 3067637 | c.309G>A | synonymous_variant | 0.56 | para-aminosalicylic_acid | |
thyX | 3067652 | c.294T>C | synonymous_variant | 0.56 | para-aminosalicylic_acid | |
thyX | 3067661 | c.285C>G | synonymous_variant | 0.62 | para-aminosalicylic_acid | |
thyX | 3067736 | c.210C>T | synonymous_variant | 0.53 | para-aminosalicylic_acid | |
thyX | 3067761 | p.Arg62Lys | missense_variant | 0.43 | para-aminosalicylic_acid | |
thyX | 3067765 | p.Leu61Ile | missense_variant | 0.43 | para-aminosalicylic_acid | |
thyX | 3067772 | c.174C>G | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyX | 3067775 | c.171C>T | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyX | 3067781 | c.165C>G | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyX | 3067793 | c.153T>C | synonymous_variant | 0.41 | para-aminosalicylic_acid | |
thyX | 3067799 | c.147G>A | synonymous_variant | 0.37 | para-aminosalicylic_acid | |
thyX | 3067802 | c.144C>G | synonymous_variant | 0.37 | para-aminosalicylic_acid | |
thyX | 3067814 | c.132T>C | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyA | 3073839 | c.633T>C | synonymous_variant | 0.7 | para-aminosalicylic_acid | |
thyA | 3073863 | c.609T>C | synonymous_variant | 0.8 | para-aminosalicylic_acid | |
thyA | 3073866 | c.606C>G | synonymous_variant | 0.8 | para-aminosalicylic_acid | |
thyA | 3073872 | p.Ile200Val | missense_variant | 0.8 | para-aminosalicylic_acid | |
thyA | 3073892 | c.580T>C | synonymous_variant | 0.82 | para-aminosalicylic_acid | |
thyA | 3073898 | p.Ala192Ser | missense_variant | 0.82 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 0.57 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625569 | c.1045T>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625572 | p.Thr348Ser | missense_variant | 0.69 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 0.71 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 0.81 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.73 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 0.7 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625616 | p.Arg333Ala | missense_variant | 0.67 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 0.73 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625636 | c.978C>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625656 | c.958T>C | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.82 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 0.78 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.68 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.67 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 0.65 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625720 | c.894G>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625729 | c.885A>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 0.76 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.69 | rifampicin | Uncertain significance |
bedaquiline | ||||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625774 | c.840G>A | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625797 | p.Val273Met | missense_variant | 0.81 | rifampicin | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625807 | c.807C>G | synonymous_variant | 0.87 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625837 | c.777C>G | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626687 | c.-74G>T | upstream_gene_variant | 0.43 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626704 | c.-91C>T | upstream_gene_variant | 0.53 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626711 | c.-98T>C | upstream_gene_variant | 0.53 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626723 | c.627C>T | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 0.5 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 0.47 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 0.56 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626774 | c.-163_-161delAGGinsCGC | upstream_gene_variant | 0.61 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 0.56 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626786 | c.564A>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3626792 | c.558G>T | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 0.5 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 0.5 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626957 | c.-344G>C | upstream_gene_variant | 0.43 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 0.4 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627065 | c.-452G>C | upstream_gene_variant | 0.5 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627071 | c.279G>T | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627074 | c.-461G>C | upstream_gene_variant | 0.5 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627080 | c.270T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 0.5 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627098 | c.252A>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.56 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627119 | c.231T>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.46 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 0.8 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627188 | c.162A>G | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 0.85 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627221 | c.129C>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627227 | c.123T>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627242 | c.108C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.93 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 0.76 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 0.72 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 0.75 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627275 | c.-662G>T | upstream_gene_variant | 0.74 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 0.68 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627299 | c.-688_-686delTTGinsCTA | upstream_gene_variant | 0.68 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627314 | c.-701C>T | upstream_gene_variant | 0.62 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 0.61 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627343 | p.Thr3Ser | missense_variant | 0.48 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627360 | c.-747G>C | upstream_gene_variant | 0.39 | rifampicin | |
bedaquiline | ||||||
rpoA | 3877553 | p.Glu319Gln | missense_variant | 0.47 | rifampicin | |
rpoA | 3877571 | p.Pro313Ala | missense_variant | 0.48 | rifampicin | |
rpoA | 3877587 | c.921A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoA | 3877656 | c.852T>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>C | synonymous_variant | 0.8 | rifampicin | |
rpoA | 3877737 | c.771G>C | synonymous_variant | 0.83 | rifampicin | |
rpoA | 3877743 | c.765T>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoA | 3877791 | c.717C>G | synonymous_variant | 0.57 | rifampicin | |
rpoA | 3877818 | c.690A>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoA | 3877848 | c.660C>T | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoA | 3877857 | c.651G>A | synonymous_variant | 0.5 | rifampicin | |
rpoA | 3877866 | c.642G>C | synonymous_variant | 0.54 | rifampicin | |
rpoA | 3877875 | c.633T>G | synonymous_variant | 0.57 | rifampicin | |
rpoA | 3877878 | c.630G>C | synonymous_variant | 0.57 | rifampicin | |
rpoA | 3877890 | c.618C>T | synonymous_variant | 0.54 | rifampicin | |
rpoA | 3877896 | c.612G>C | synonymous_variant | 0.5 | rifampicin | |
rpoA | 3877900 | p.Ser203Asn | missense_variant | 0.53 | rifampicin | |
rpoA | 3877905 | c.603A>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoA | 3877909 | p.Asn200Ser | missense_variant | 0.5 | rifampicin | |
rpoA | 3877989 | c.519A>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoA | 3878130 | c.378C>G | synonymous_variant | 0.5 | rifampicin | |
rpoA | 3878141 | p.Met123Leu | missense_variant | 0.54 | rifampicin | Uncertain significance |
rpoA | 3878143 | p.Gly122Asp | missense_variant | 0.58 | rifampicin | Uncertain significance |
rpoA | 3878157 | c.351C>G | synonymous_variant | 0.73 | rifampicin | |
rpoA | 3878217 | c.291A>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoA | 3878226 | c.282C>G | synonymous_variant | 0.59 | rifampicin | |
rpoA | 3878232 | c.276G>C | synonymous_variant | 0.53 | rifampicin | |
rpoA | 3878247 | c.261G>C | synonymous_variant | 0.5 | rifampicin | |
rpoA | 3878271 | c.237T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoA | 3878284 | p.Glu75Ala | missense_variant | 0.5 | rifampicin | |
rpoA | 3878292 | c.216T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoA | 3878298 | c.210A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoA | 3878304 | c.204G>C | synonymous_variant | 0.48 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoA | 3878322 | c.186A>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoA | 3878331 | c.177A>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoA | 3878334 | c.174T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoA | 3878346 | c.162T>C | synonymous_variant | 0.52 | rifampicin | |
rpoA | 3878364 | c.144A>T | synonymous_variant | 0.53 | rifampicin | |
rpoA | 3878367 | c.141C>G | synonymous_variant | 0.56 | rifampicin | |
rpoA | 3878376 | c.132G>C | synonymous_variant | 0.63 | rifampicin | |
rpoA | 3878385 | c.123C>G | synonymous_variant | 0.56 | rifampicin | |
rpoA | 3878388 | c.120C>G | synonymous_variant | 0.67 | rifampicin | |
rpoA | 3878391 | c.117T>C | synonymous_variant | 0.67 | rifampicin | |
rpoA | 3878415 | c.93C>T | synonymous_variant | 0.67 | rifampicin | |
rpoA | 3878424 | c.84G>C | synonymous_variant | 0.76 | rifampicin | |
rpoA | 3878436 | c.72A>G | synonymous_variant | 0.7 | rifampicin | |
rpoA | 3878442 | c.66G>C | synonymous_variant | 0.67 | rifampicin | |
rpoA | 3878454 | c.54A>C | synonymous_variant | 0.57 | rifampicin | |
rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.55 | rifampicin | |
rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.46 | rifampicin | Uncertain significance |
rpoA | 3878986 | c.-479G>C | upstream_gene_variant | 0.67 | rifampicin | |
rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 0.64 | rifampicin | Uncertain significance |
rpoA | 3879005 | c.-499_-498delAAinsCG | upstream_gene_variant | 0.71 | rifampicin | |
rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 0.69 | rifampicin | |
clpC1 | 4038293 | c.2412G>C | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4038302 | c.2403C>G | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4038308 | c.2397G>T | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4038314 | c.2391T>C | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4038317 | c.2388G>C | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4038320 | c.2385G>T | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4038356 | c.2349T>C | synonymous_variant | 0.71 | pyrazinamide | |
clpC1 | 4038359 | c.2346A>G | synonymous_variant | 0.71 | pyrazinamide | |
clpC1 | 4038368 | c.2337T>C | synonymous_variant | 0.71 | pyrazinamide | |
clpC1 | 4038388 | c.2317T>C | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4038392 | c.2313C>T | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4038398 | c.2307G>T | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4038403 | c.2302T>C | synonymous_variant | 0.54 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038530 | p.Glu725Asp | missense_variant | 0.57 | pyrazinamide | |
clpC1 | 4038541 | c.2164C>T | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4038596 | c.2109A>G | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4038623 | c.2082A>G | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4038640 | p.Asp689Asn | missense_variant | 0.5 | pyrazinamide | |
clpC1 | 4038749 | c.1956C>G | synonymous_variant | 0.58 | pyrazinamide | |
clpC1 | 4038755 | c.1950G>T | synonymous_variant | 0.58 | pyrazinamide | |
clpC1 | 4038770 | c.1935C>T | synonymous_variant | 0.73 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4038845 | c.1860G>C | synonymous_variant | 0.73 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.75 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.77 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.75 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.76 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.81 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.81 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039004 | c.1701C>G | synonymous_variant | 0.8 | pyrazinamide | |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.79 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.79 | pyrazinamide | |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.77 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.79 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.8 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.82 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.78 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.78 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.76 | pyrazinamide | |
clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4039183 | c.1522T>C | synonymous_variant | 0.8 | pyrazinamide | |
clpC1 | 4039186 | c.1519C>T | synonymous_variant | 0.81 | pyrazinamide | |
clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.75 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039229 | c.1476C>G | synonymous_variant | 0.71 | pyrazinamide | |
clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.78 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.75 | pyrazinamide | |
clpC1 | 4039295 | c.1410A>C | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4039319 | c.1386T>C | synonymous_variant | 0.54 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039322 | c.1383T>C | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4039328 | c.1377A>C | synonymous_variant | 0.55 | pyrazinamide | |
clpC1 | 4039331 | c.1374C>G | synonymous_variant | 0.6 | pyrazinamide | |
clpC1 | 4039337 | p.Thr456Gln | missense_variant | 0.6 | pyrazinamide | |
clpC1 | 4039349 | c.1356C>T | synonymous_variant | 0.6 | pyrazinamide | |
clpC1 | 4039352 | c.1353C>G | synonymous_variant | 0.6 | pyrazinamide | |
clpC1 | 4039364 | c.1341C>G | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4039556 | c.1149G>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4039559 | c.1146C>G | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039562 | c.1143C>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039565 | c.1140G>T | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039576 | p.Ala377Pro | missense_variant | 0.47 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.44 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039589 | c.1116G>C | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4039661 | c.1044T>G | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4039664 | c.1041G>C | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.73 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4039946 | c.759A>C | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4039979 | c.726C>G | synonymous_variant | 0.63 | pyrazinamide | |
clpC1 | 4039988 | c.717C>G | synonymous_variant | 0.65 | pyrazinamide | |
clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.71 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.72 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4040036 | c.669C>G | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 0.75 | pyrazinamide | |
clpC1 | 4040093 | c.612C>G | synonymous_variant | 0.75 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.7 | pyrazinamide | |
clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.5 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040171 | c.534C>G | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4040480 | c.225T>G | synonymous_variant | 0.37 | pyrazinamide | |
panD | 4044872 | c.-591C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
panD | 4045019 | c.-738G>C | upstream_gene_variant | 0.5 | pyrazinamide | |
panD | 4045022 | c.-741C>G | upstream_gene_variant | 0.54 | pyrazinamide | |
panD | 4045028 | c.-747C>G | upstream_gene_variant | 0.58 | pyrazinamide | |
panD | 4045034 | c.-753A>C | upstream_gene_variant | 0.47 | pyrazinamide | |
panD | 4045055 | c.-774T>G | upstream_gene_variant | 0.5 | pyrazinamide | |
panD | 4045067 | c.-786C>G | upstream_gene_variant | 0.46 | pyrazinamide | |
panD | 4045070 | c.-789C>T | upstream_gene_variant | 0.46 | pyrazinamide | |
panD | 4045076 | c.-795A>C | upstream_gene_variant | 0.46 | pyrazinamide | |
panD | 4045088 | c.-807T>C | upstream_gene_variant | 0.43 | pyrazinamide | |
glpK | 4139143 | c.613T>C | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139165 | c.591A>G | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139168 | c.588T>C | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139177 | c.579T>C | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139183 | c.573T>C | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139186 | c.570G>C | synonymous_variant | 0.73 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4139195 | c.561G>T | synonymous_variant | 0.73 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
embC | 4240780 | c.918T>C | synonymous_variant | 0.69 | ethambutol | |
embC | 4240783 | c.921G>C | synonymous_variant | 0.64 | ethambutol | |
embC | 4240789 | c.927T>C | synonymous_variant | 0.62 | ethambutol | |
embC | 4240819 | c.957A>G | synonymous_variant | 0.58 | ethambutol | |
embC | 4240828 | c.966G>A | synonymous_variant | 0.53 | ethambutol | |
embC | 4240831 | c.969T>G | synonymous_variant | 0.53 | ethambutol | |
embC | 4240867 | c.1005T>C | synonymous_variant | 0.37 | ethambutol | |
embC | 4241053 | c.1191G>C | synonymous_variant | 0.69 | ethambutol | |
embC | 4241089 | c.1227C>G | synonymous_variant | 0.7 | ethambutol | |
embC | 4241095 | c.1233C>T | synonymous_variant | 0.68 | ethambutol | |
embC | 4241107 | c.1245G>C | synonymous_variant | 0.67 | ethambutol | |
embC | 4241140 | c.1278A>G | synonymous_variant | 0.65 | ethambutol | Not assoc w R - Interim |
embC | 4241146 | c.1284C>G | synonymous_variant | 0.65 | ethambutol | |
embC | 4241158 | c.1296T>C | synonymous_variant | 0.68 | ethambutol | |
embC | 4241161 | c.1299C>G | synonymous_variant | 0.69 | ethambutol | Not assoc w R - Interim |
embC | 4241162 | c.1300T>C | synonymous_variant | 0.65 | ethambutol | |
embC | 4241170 | c.1308G>C | synonymous_variant | 0.65 | ethambutol | |
embC | 4241173 | c.1311C>T | synonymous_variant | 0.69 | ethambutol | |
embC | 4241203 | c.1341T>C | synonymous_variant | 0.69 | ethambutol | |
embC | 4241206 | c.1344G>C | synonymous_variant | 0.69 | ethambutol | Not assoc w R - Interim |
embC | 4241218 | c.1356G>C | synonymous_variant | 0.58 | ethambutol | |
embC | 4241374 | c.1512T>C | synonymous_variant | 0.55 | ethambutol | |
embC | 4241380 | c.1518A>C | synonymous_variant | 0.55 | ethambutol | |
embC | 4241394 | p.Lys511Ser | missense_variant | 0.6 | ethambutol | |
embC | 4241567 | p.Ile569Val | missense_variant | 0.5 | ethambutol | |
embC | 4241572 | c.1710C>G | synonymous_variant | 0.56 | ethambutol | |
embC | 4241578 | c.1716G>C | synonymous_variant | 0.5 | ethambutol | |
embC | 4241584 | c.1722T>C | synonymous_variant | 0.5 | ethambutol | |
embC | 4241587 | c.1725C>G | synonymous_variant | 0.53 | ethambutol | |
embC | 4241591 | p.Leu577Val | missense_variant | 0.5 | ethambutol | |
embC | 4241611 | c.1749G>C | synonymous_variant | 0.5 | ethambutol | |
embC | 4241614 | c.1752A>C | synonymous_variant | 0.47 | ethambutol | |
embC | 4241626 | c.1764T>C | synonymous_variant | 0.44 | ethambutol | |
embC | 4241635 | c.1773G>C | synonymous_variant | 0.41 | ethambutol | |
embC | 4242643 | c.2781C>T | synonymous_variant | 0.91 | ethambutol | Not assoc w R |
embA | 4245137 | c.1905T>C | synonymous_variant | 0.35 | ethambutol | |
embA | 4245146 | c.1914G>A | synonymous_variant | 0.33 | ethambutol | |
embA | 4245149 | c.1917C>G | synonymous_variant | 0.35 | ethambutol | |
embA | 4245153 | p.Ile641Val | missense_variant | 0.35 | ethambutol | |
embA | 4245182 | c.1950T>C | synonymous_variant | 0.33 | ethambutol | |
embA | 4245189 | c.1957C>T | synonymous_variant | 0.3 | ethambutol | |
embA | 4245198 | p.Leu656Ile | missense_variant | 0.3 | ethambutol | |
embA | 4245207 | c.1975T>C | synonymous_variant | 0.3 | ethambutol | |
embA | 4246235 | c.3003G>A | synonymous_variant | 0.43 | ethambutol | Not assoc w R - Interim |
embA | 4246242 | p.Gln1004Gly | missense_variant | 0.4 | ethambutol | |
embB | 4246250 | c.-264G>C | upstream_gene_variant | 0.44 | ethambutol | |
embB | 4246256 | c.-258G>T | upstream_gene_variant | 0.47 | ethambutol | |
embB | 4246259 | c.-255G>C | upstream_gene_variant | 0.5 | ethambutol | |
embA | 4246264 | p.His1011Arg | missense_variant | 0.5 | ethambutol | |
embB | 4246292 | c.-222A>G | upstream_gene_variant | 0.5 | ethambutol | |
embA | 4246305 | p.Ser1025Glu | missense_variant | 0.5 | ethambutol | |
embA | 4246308 | p.Thr1026Ala | missense_variant | 0.5 | ethambutol | |
embB | 4246316 | c.-198T>G | upstream_gene_variant | 0.5 | ethambutol | |
embB | 4246319 | c.-195G>C | upstream_gene_variant | 0.5 | ethambutol | |
embB | 4247539 | c.1026T>C | synonymous_variant | 0.58 | ethambutol | |
embB | 4247940 | p.Leu476Trp | missense_variant | 0.64 | ethambutol | |
embB | 4247945 | c.1432T>C | synonymous_variant | 0.6 | ethambutol | |
embB | 4247951 | p.Ser480Ala | missense_variant | 0.6 | ethambutol | |
embB | 4247956 | c.1443G>C | synonymous_variant | 0.6 | ethambutol | Not assoc w R - Interim |
embB | 4248070 | c.1557T>C | synonymous_variant | 0.5 | ethambutol | |
embB | 4248220 | c.1707A>C | synonymous_variant | 0.37 | ethambutol | |
embB | 4248304 | c.1791G>C | synonymous_variant | 0.38 | ethambutol | |
embB | 4249498 | c.2985G>C | synonymous_variant | 0.62 | ethambutol | |
embB | 4249521 | p.Ala1003Val | missense_variant | 0.62 | ethambutol | |
embB | 4249525 | c.3012T>C | synonymous_variant | 0.6 | ethambutol | Not assoc w R - Interim |
embB | 4249529 | p.Ile1006Val | missense_variant | 0.56 | ethambutol | |
embB | 4249532 | p.Ala1007Thr | missense_variant | 0.56 | ethambutol | Uncertain significance |
embB | 4249537 | c.3024A>G | synonymous_variant | 0.56 | ethambutol | |
embB | 4249543 | c.3030G>C | synonymous_variant | 0.53 | ethambutol | |
embB | 4249546 | c.3033G>A | synonymous_variant | 0.53 | ethambutol | |
aftB | 4268129 | c.708T>G | synonymous_variant | 0.55 | ethambutol | |
aftB | 4268138 | c.699A>C | synonymous_variant | 0.55 | ethambutol | Not assoc w R - Interim |
aftB | 4268144 | c.693T>C | synonymous_variant | 0.54 | ethambutol | |
aftB | 4268164 | p.Gln225Glu | missense_variant | 0.6 | ethambutol | |
aftB | 4268169 | p.Ala223Gly | missense_variant | 0.58 | ethambutol | |
aftB | 4268171 | c.666G>C | synonymous_variant | 0.54 | ethambutol | |
aftB | 4268179 | c.658T>C | synonymous_variant | 0.46 | ethambutol | Not assoc w R - Interim |
aftB | 4268182 | p.Phe219Leu | missense_variant | 0.43 | ethambutol | |
aftB | 4268183 | c.654A>T | synonymous_variant | 0.43 | ethambutol | |
aftB | 4268193 | p.Leu215Ala | missense_variant | 0.46 | ethambutol | |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin |