TB-Profiler result

Run: SRR1196474
Summary

Run ID: SRR1196474

Sample name:

Date: 2024-10-04T02:18:18.257224

Number of reads: 476393

Percentage reads mapped: 46.5

Median coverage: 10.0

Strain: lineage3.1.1

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage3.1.1 East-African-Indian RD750 0.82
lineage3.1 East-African-Indian RD750 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.Met306Ile Assoc w R
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.72 streptomycin Uncertain significance Mutation from literature
embB 4247431 p.Met306Ile missense_variant 0.58 ethambutol Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 30 c.30C>G synonymous_variant 0.26 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.64 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.58 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.58 isoniazid
dnaA 768 c.768C>G synonymous_variant 0.44 isoniazid
dnaA 771 c.771A>C synonymous_variant 0.47 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.47 isoniazid
dnaA 786 c.786C>T synonymous_variant 0.5 isoniazid
dnaA 792 c.792C>T synonymous_variant 0.47 isoniazid
dnaA 942 c.942C>G synonymous_variant 0.47 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.47 isoniazid
dnaA 955 c.955A>C synonymous_variant 0.4 isoniazid
dnaA 960 c.960C>A synonymous_variant 0.4 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.38 isoniazid Not assoc w R - Interim
dnaA 1014 c.1014C>G synonymous_variant 0.38 isoniazid
gyrB 5809 c.570C>G synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrB 5812 c.573C>G synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrB 5824 c.585A>G synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrB 5827 c.588G>A synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrB 5849 c.610C>T synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrB 6136 c.897G>A synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6139 c.900G>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.4 levofloxacin
moxifloxacin
gyrB 6248 c.1009_1011delCTAinsTTG synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrB 6256 c.1017G>A synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrB 6289 c.1050C>T synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 7514 c.213C>G synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 8135 c.834C>G synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 8237 c.936A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 0.53 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8276 c.975G>A synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.53 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.47 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8672 c.1371A>G synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8966 c.1665C>G synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.55 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 9122 c.1821C>G synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9143 c.1842T>C synonymous_variant 0.53 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9152 c.1851C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9153 p.Thr618Glu missense_variant 0.5 levofloxacin
moxifloxacin
gyrA 9158 c.1857C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9161 c.1860C>G synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 0.5 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
Rv0010c 13879 c.-321T>C upstream_gene_variant 0.6 isoniazid
Rv0010c 13890 c.-332T>C upstream_gene_variant 0.6 isoniazid
Rv0010c 13893 c.-335T>G upstream_gene_variant 0.64 isoniazid
Rv0010c 13897 c.-339C>T upstream_gene_variant 0.64 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.58 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.54 isoniazid
fgd1 490848 c.66A>G synonymous_variant 0.7 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 490851 c.69A>T synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fgd1 491742 c.960T>C synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R
Rv0565c 656448 p.Ile341Val missense_variant 0.54 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 0.54 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 0.58 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 0.5 ethionamide
Rv0565c 656475 c.996A>G synonymous_variant 0.53 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 0.57 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 0.57 ethionamide Not assoc w R - Interim
Rv0565c 656493 c.978C>G synonymous_variant 0.56 ethionamide
Rv0565c 656502 c.969C>T synonymous_variant 0.5 ethionamide
Rv0565c 656511 c.960T>C synonymous_variant 0.5 ethionamide Not assoc w R - Interim
Rv0565c 657081 c.390G>A synonymous_variant 0.91 ethionamide Not assoc w R - Interim
Rv0565c 657300 c.171C>G synonymous_variant 0.53 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.5 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 0.5 ethionamide
hadA 731732 c.-198G>A upstream_gene_variant 0.38 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.47 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.6 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.65 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.68 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.61 isoniazid
hadA 731816 c.-114G>A upstream_gene_variant 0.67 isoniazid
hadA 732253 c.324T>C synonymous_variant 0.47 isoniazid
hadA 732259 c.330T>C synonymous_variant 0.53 isoniazid
hadA 732268 c.339T>G synonymous_variant 0.53 isoniazid
hadA 732270 p.Glu114Val missense_variant 0.53 isoniazid
hadA 732272 p.Ala115Ser missense_variant 0.56 isoniazid
hadA 732295 c.366G>C synonymous_variant 0.68 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.59 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.62 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.59 isoniazid
hadA 732329 p.Leu134Val missense_variant 0.6 isoniazid Uncertain significance
hadA 732337 c.408G>A synonymous_variant 0.55 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.65 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.58 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.61 isoniazid
nusG 734421 c.168A>G synonymous_variant 0.53 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.5 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.55 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.58 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.6 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.53 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.53 rifampicin
nusG 734841 c.588G>C synonymous_variant 0.62 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.62 rifampicin
nusG 734850 c.597C>G synonymous_variant 0.62 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.57 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.57 rifampicin
nusG 734882 p.Ala210Gly missense_variant 0.6 rifampicin
nusG 734886 c.633A>G synonymous_variant 0.57 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.57 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.56 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.56 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.56 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.5 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.5 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.64 rifampicin
rpoB 760412 c.606C>G synonymous_variant 0.68 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760472 c.666C>T synonymous_variant 0.52 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 760611 c.805T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.71 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760715 c.909C>G synonymous_variant 0.7 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761219 c.1413G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 0.57 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.52 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.48 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762266 c.2460T>C synonymous_variant 0.62 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762314 c.2508C>T synonymous_variant 0.64 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.69 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.57 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.64 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.75 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.46 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.64 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.64 rifampicin Uncertain significance
rpoC 762521 c.-849C>T upstream_gene_variant 0.64 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.55 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.55 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.55 rifampicin
rpoC 762551 c.-819C>G upstream_gene_variant 0.46 rifampicin
rpoB 762929 c.3123G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.67 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763013 c.-357C>G upstream_gene_variant 0.7 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 763067 c.-303C>G upstream_gene_variant 0.75 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.58 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.52 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763190 c.-180C>T upstream_gene_variant 0.37 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.32 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.32 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.32 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.32 rifampicin
rpoB 763227 c.3421C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 763238 c.3432T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>G synonymous_variant 0.42 rifampicin
rpoC 763411 c.42T>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.44 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.43 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.4 rifampicin
rpoC 763492 c.123G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763606 c.237C>T synonymous_variant 0.52 rifampicin
rpoC 763636 c.267T>C synonymous_variant 0.5 rifampicin
rpoC 763657 c.288G>A synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.47 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.45 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.39 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.42 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.55 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.6 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.38 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.5 rifampicin
rpoC 763853 p.Val162Ile missense_variant 0.41 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.54 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.46 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.5 rifampicin
rpoC 764112 p.Tyr248Phe missense_variant 0.5 rifampicin
rpoC 764116 c.747C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.5 rifampicin
rpoC 764215 c.846A>G synonymous_variant 0.62 rifampicin
rpoC 764236 c.867G>A synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.53 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.53 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.5 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.52 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764338 c.969G>A synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>C synonymous_variant 0.53 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.55 rifampicin
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036A>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.7 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.69 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.69 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.69 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.76 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.79 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.81 rifampicin
rpoC 764551 c.1182G>C synonymous_variant 0.81 rifampicin
rpoC 764554 c.1185C>T synonymous_variant 0.82 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764593 c.1224C>T synonymous_variant 0.73 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.67 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.64 rifampicin
rpoC 764932 c.1563C>A synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.5 rifampicin Not assoc w R
rpoC 765047 c.1678T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765346 c.1977C>G synonymous_variant 0.67 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765364 c.1995G>A synonymous_variant 0.67 rifampicin
rpoC 765383 p.Met672Leu missense_variant 0.57 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.67 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.59 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.55 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.47 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.47 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.5 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.75 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.6 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.55 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.5 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.5 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.5 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.42 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.42 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.5 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.5 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.38 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.35 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.4 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.38 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.38 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.4 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.4 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 0.41 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.44 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.53 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.6 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 0.62 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.67 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.75 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.64 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.53 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 0.5 rifampicin
rpoC 766583 p.Gly1072Ser missense_variant 0.5 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.5 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.5 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.5 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.6 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.62 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.62 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.57 rifampicin
rpoC 766795 c.3426C>T synonymous_variant 0.46 rifampicin
rpoC 766801 c.3432C>G synonymous_variant 0.5 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.53 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.6 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.7 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.5 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.59 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.71 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.47 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
mmpL5 775966 p.Ala839Ser missense_variant 0.56 bedaquiline
clofazimine
mmpL5 775975 c.2506T>C synonymous_variant 0.6 bedaquiline
clofazimine
mmpL5 775981 p.Leu834Met missense_variant 0.6 bedaquiline
clofazimine
mmpL5 775997 c.2484T>C synonymous_variant 0.64 bedaquiline
clofazimine
mmpL5 776000 p.Leu827Phe missense_variant 0.64 bedaquiline
clofazimine
mmpL5 776009 c.2472A>G synonymous_variant 0.6 bedaquiline
clofazimine
mmpL5 776678 c.1803G>C synonymous_variant 0.41 bedaquiline
clofazimine
mmpL5 776693 p.Val596Thr missense_variant 0.41 bedaquiline
clofazimine
mmpL5 776705 c.1776C>T synonymous_variant 0.39 bedaquiline
clofazimine
mmpL5 776756 p.Asp575Glu missense_variant 0.35 bedaquiline
clofazimine
mmpL5 777110 c.1371T>G synonymous_variant 0.5 bedaquiline
clofazimine
mmpL5 777115 p.Met456Leu missense_variant 0.5 bedaquiline
clofazimine
mmpL5 777116 c.1365C>T synonymous_variant 0.5 bedaquiline
clofazimine
mmpL5 777133 p.Val450Ile missense_variant 0.47 bedaquiline
clofazimine
mmpL5 777158 c.1323C>G synonymous_variant 0.57 bedaquiline
clofazimine
mmpL5 777164 c.1317C>G synonymous_variant 0.59 bedaquiline
clofazimine
mmpL5 777170 c.1311T>C synonymous_variant 0.6 bedaquiline
clofazimine
mmpL5 777176 p.Glu435Asp missense_variant 0.57 bedaquiline
clofazimine
mmpL5 777191 c.1290C>G synonymous_variant 0.53 bedaquiline
clofazimine
mmpL5 777194 c.1287A>G synonymous_variant 0.5 bedaquiline
clofazimine
rpsL 781649 c.90T>C synonymous_variant 0.53 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.53 streptomycin
rpsL 781772 c.213C>A synonymous_variant 0.5 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.61 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.56 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.68 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.7 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.74 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.74 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.72 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.68 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.68 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.53 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.5 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.55 streptomycin Uncertain significance
rplC 800567 c.-242A>G upstream_gene_variant 0.56 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.6 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.75 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.73 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.75 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.75 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.76 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.77 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.73 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.7 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.71 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.71 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.64 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.64 linezolid
rplC 800794 c.-15A>G upstream_gene_variant 0.57 linezolid
rplC 800796 c.-13A>G upstream_gene_variant 0.57 linezolid
rplC 800798 c.-10_-9delGG upstream_gene_variant 0.59 linezolid
rplC 800814 c.6A>G synonymous_variant 0.58 linezolid
rplC 800817 c.9A>T synonymous_variant 0.56 linezolid
rplC 800844 c.36T>C synonymous_variant 0.63 linezolid
rplC 800865 c.57A>G synonymous_variant 0.46 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.5 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.6 linezolid
rplC 801402 c.594T>C synonymous_variant 0.5 linezolid
rplC 801405 c.597T>C synonymous_variant 0.5 linezolid
rplC 801423 c.615G>C synonymous_variant 0.54 linezolid
rplC 801426 c.618C>G synonymous_variant 0.54 linezolid
rplC 801427 p.Met207Val missense_variant 0.54 linezolid
rplC 801438 c.630T>C synonymous_variant 0.62 linezolid
rplC 801442 p.Ile212Val missense_variant 0.54 linezolid
fbiC 1303534 p.Ser202Ala missense_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1303539 c.609G>C synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1303575 c.645G>C synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1303602 c.672A>G synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1303605 c.675C>G synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1303608 c.678G>A synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fbiC 1303614 c.684C>T synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1303617 c.687C>G synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1303761 c.831T>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1303785 c.855G>C synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1303789 p.Ile287Val missense_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1303818 c.888C>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1303836 c.906G>C synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1303845 c.915C>G synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1303846 p.Phe306Val missense_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1303854 c.924T>C synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1303860 c.930A>C synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fbiC 1303920 c.990C>T synonymous_variant 0.82 pretomanid
delamanid
clofazimine
fbiC 1303944 c.1014G>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1303947 c.1017T>G synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1303948 p.Gly340Arg missense_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1303953 p.Asp341Glu missense_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1303954 p.Glu342Gln missense_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1303961 p.Arg344Leu missense_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1303971 c.1041T>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1303980 c.1050G>A synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304748 c.1818T>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304778 c.1848T>C synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304784 c.1854T>C synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>G synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1304808 c.1878C>G synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1304811 c.1881C>G synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304817 c.1887T>C synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiC 1304853 c.1923C>T synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1304856 c.1926C>G synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304869 c.1939C>T synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1304875 p.Ile649Val missense_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304883 p.Glu651Asp missense_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304891 p.Ile654Thr missense_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304893 p.Gly655Ser missense_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304958 c.2028T>G synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304983 c.2053C>T synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304994 c.2064A>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304995 p.Leu689Met missense_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1305006 c.2076A>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1305012 c.2082G>C synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1305015 c.2085G>C synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1305021 c.2091C>G synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1305030 c.2100G>C synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1305033 c.2103T>G synonymous_variant 0.5 pretomanid
delamanid
clofazimine
atpE 1461170 c.126A>G synonymous_variant 0.52 bedaquiline
atpE 1461185 c.141G>T synonymous_variant 0.58 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.59 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.53 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.54 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 0.48 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.5 bedaquiline
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.67 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.67 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.7 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.7 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.69 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.69 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.44 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.48 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.48 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.5 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.5 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.74 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.68 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.82 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.81 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.7 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1473677 n.20C>G non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1473987 n.330G>A non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.61 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474960 n.1303C>G non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474963 n.1306G>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474965 n.1308G>C non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.72 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.69 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476031 n.2374C>T non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1476214 n.2557G>A non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.59 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.64 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1476733 n.3076C>T non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
inhA 1673667 c.-535A>G upstream_gene_variant 0.6 isoniazid
ethionamide
inhA 1673679 c.-523T>G upstream_gene_variant 0.64 isoniazid
ethionamide
inhA 1673685 c.-517C>T upstream_gene_variant 0.58 isoniazid
ethionamide
inhA 1673710 c.-492C>A upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1673716 c.-486_-485delGCinsAA upstream_gene_variant 0.75 isoniazid
ethionamide
inhA 1674537 c.336C>G synonymous_variant 0.79 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 0.69 isoniazid
ethionamide
inhA 1674546 c.345T>C synonymous_variant 0.69 isoniazid
ethionamide
inhA 1674549 c.348G>C synonymous_variant 0.69 isoniazid
ethionamide
inhA 1674552 c.351C>G synonymous_variant 0.69 isoniazid
ethionamide
inhA 1674555 c.354G>A synonymous_variant 0.65 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 0.55 isoniazid
ethionamide
inhA 1674582 c.381T>C synonymous_variant 0.5 isoniazid
ethionamide
inhA 1674585 c.384T>C synonymous_variant 0.47 isoniazid
ethionamide
inhA 1674589 p.Met130Leu missense_variant 0.42 isoniazid
ethionamide
inhA 1674597 c.396G>A synonymous_variant 0.48 isoniazid
ethionamide
inhA 1674601 p.Leu134Thr missense_variant 0.48 isoniazid
ethionamide
inhA 1674624 c.423A>C synonymous_variant 0.5 isoniazid
ethionamide
inhA 1674630 c.429C>G synonymous_variant 0.45 isoniazid
ethionamide
inhA 1674660 c.459G>C synonymous_variant 0.65 isoniazid
ethionamide
inhA 1674672 c.471C>G synonymous_variant 0.67 isoniazid
ethionamide
inhA 1674703 c.502T>C synonymous_variant 0.62 isoniazid
ethionamide
inhA 1674789 c.588G>C synonymous_variant 0.38 isoniazid
ethionamide
inhA 1674822 c.621C>G synonymous_variant 0.5 isoniazid
ethionamide
inhA 1674828 c.627G>A synonymous_variant 0.46 isoniazid
ethionamide
inhA 1674846 p.Ile215Met missense_variant 0.64 isoniazid
ethionamide
inhA 1674864 c.663C>T synonymous_variant 0.54 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674879 c.678T>C synonymous_variant 0.62 isoniazid
ethionamide
inhA 1674900 c.699G>A synonymous_variant 0.56 isoniazid
ethionamide
inhA 1674903 c.702T>C synonymous_variant 0.5 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 0.5 isoniazid
ethionamide
inhA 1674909 c.708G>A synonymous_variant 0.5 isoniazid
ethionamide
inhA 1674942 c.741T>G synonymous_variant 0.44 isoniazid
ethionamide
rpsA 1833532 c.-10A>C upstream_gene_variant 0.55 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 0.62 pyrazinamide Uncertain significance
rpsA 1833568 c.27G>C synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.72 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.7 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.72 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.67 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.5 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.47 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.47 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.47 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.44 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.47 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.41 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.47 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.56 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.6 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.59 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.59 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.64 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.62 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.74 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.61 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.65 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.55 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.59 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.64 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.7 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.68 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.46 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.47 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.56 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.61 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
rpsA 1834378 c.837T>C synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.71 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.56 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.6 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.65 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.67 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.64 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.62 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.67 pyrazinamide
rpsA 1834510 c.969C>T synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
rpsA 1834513 c.972C>G synonymous_variant 0.82 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.71 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.67 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.67 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.64 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.67 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.67 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.65 pyrazinamide
rpsA 1834684 c.1143C>T synonymous_variant 0.65 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.65 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.7 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.64 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 0.6 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.6 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.6 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.56 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.6 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.64 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.8 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
katG 2155691 c.421T>C synonymous_variant 0.64 isoniazid
katG 2155695 c.417C>G synonymous_variant 0.64 isoniazid
katG 2155704 c.408C>G synonymous_variant 0.58 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.69 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.69 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.64 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 0.42 isoniazid
kasA 2518459 c.345T>C synonymous_variant 0.5 isoniazid
kasA 2518462 c.348A>C synonymous_variant 0.47 isoniazid
kasA 2518468 c.354A>C synonymous_variant 0.56 isoniazid
kasA 2518474 c.360G>A synonymous_variant 0.58 isoniazid
kasA 2518480 c.366T>C synonymous_variant 0.58 isoniazid
kasA 2518483 c.369C>G synonymous_variant 0.61 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.52 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.5 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.48 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.5 isoniazid
kasA 2518540 c.426T>C synonymous_variant 0.57 isoniazid
kasA 2518768 c.654C>T synonymous_variant 0.73 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.79 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.85 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.85 isoniazid
kasA 2518792 c.678C>A synonymous_variant 0.86 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.81 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.71 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.73 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.53 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.5 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.5 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.46 isoniazid
kasA 2519068 c.954C>T synonymous_variant 0.67 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 0.64 isoniazid
kasA 2519107 c.993T>C synonymous_variant 0.92 isoniazid
kasA 2519108 p.Asp332Gln missense_variant 0.85 isoniazid
kasA 2519122 c.1008G>C synonymous_variant 0.88 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.86 isoniazid
kasA 2519158 c.1044C>T synonymous_variant 0.8 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.8 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 0.75 isoniazid
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0 isoniazid Not assoc w R
ahpC 2726303 c.111T>C synonymous_variant 0.64 isoniazid
ahpC 2726311 p.Ser40Asn missense_variant 0.64 isoniazid
ahpC 2726336 c.144G>C synonymous_variant 0.46 isoniazid
ahpC 2726348 c.156T>C synonymous_variant 0.6 isoniazid
folC 2746375 c.1224G>C synonymous_variant 0.46 para-aminosalicylic_acid
folC 2746390 c.1209G>C synonymous_variant 0.4 para-aminosalicylic_acid
folC 2746393 c.1206C>G synonymous_variant 0.43 para-aminosalicylic_acid
folC 2746401 p.Ser400Ala missense_variant 0.55 para-aminosalicylic_acid
folC 2746402 c.1197T>C synonymous_variant 0.55 para-aminosalicylic_acid
folC 2746414 p.Glu395Gln missense_variant 0.46 para-aminosalicylic_acid
folC 2746420 c.1179A>C synonymous_variant 0.46 para-aminosalicylic_acid
folC 2746426 c.1173G>C synonymous_variant 0.46 para-aminosalicylic_acid
folC 2746438 c.1161G>C synonymous_variant 0.46 para-aminosalicylic_acid
folC 2746451 p.Gly383Ala missense_variant 0.5 para-aminosalicylic_acid
folC 2747071 c.528C>G synonymous_variant 0.58 para-aminosalicylic_acid
folC 2747086 c.513A>C synonymous_variant 0.64 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 0.58 para-aminosalicylic_acid
folC 2747101 c.498G>C synonymous_variant 0.58 para-aminosalicylic_acid
Rv2477c 2782483 c.1560G>C synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782498 c.1545C>T synonymous_variant 0.6 kanamycin Not assoc w R
levofloxacin Not assoc w R
moxifloxacin Not assoc w R
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R
ethambutol Not assoc w R
amikacin Not assoc w R
Rv2477c 2782513 c.1530G>T synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782522 c.1521G>C synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782546 c.1497C>G synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782912 p.Ser377Thr missense_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782927 p.Thr372Glu missense_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782930 c.1113G>A synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782936 c.1107G>T synonymous_variant 0.56 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 0.39 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782966 c.1077C>A synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782969 c.1074A>C synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782972 c.1071G>C synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 0.73 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 0.77 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783101 c.942G>T synonymous_variant 0.77 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783107 c.936G>A synonymous_variant 0.77 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.77 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 0.81 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.82 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783182 c.861C>G synonymous_variant 0.84 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783185 c.858G>A synonymous_variant 0.83 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.83 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.82 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 0.75 kanamycin
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.71 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.56 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.44 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.64 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.68 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.71 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.7 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.7 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.7 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.7 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.62 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.81 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.95 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.95 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783929 c.114C>G synonymous_variant 0.95 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783932 c.111C>T synonymous_variant 0.96 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.78 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 0.8 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783962 c.81T>C synonymous_variant 0.76 kanamycin Not assoc w R - Interim
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 0.82 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.82 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.76 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2784405 c.-363T>C upstream_gene_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784428 c.-386T>C upstream_gene_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784429 c.-387A>G upstream_gene_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784432 c.-390A>C upstream_gene_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784435 c.-393C>G upstream_gene_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784452 c.-410C>T upstream_gene_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784454 c.-412G>A upstream_gene_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784456 c.-414A>C upstream_gene_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784472 c.-430C>A upstream_gene_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784477 c.-435T>C upstream_gene_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2752c 3066009 c.183G>C synonymous_variant 0.46 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066018 c.174T>C synonymous_variant 0.46 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066330 c.-139G>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066335 c.-144T>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066339 c.-148G>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067313 c.633G>T synonymous_variant 0.53 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 0.53 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.53 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.54 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.57 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.6 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.69 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 0.54 para-aminosalicylic_acid
thyX 3067462 c.484C>T synonymous_variant 0.47 para-aminosalicylic_acid
thyX 3067465 p.Ile161Val missense_variant 0.47 para-aminosalicylic_acid
thyX 3067466 c.480G>C synonymous_variant 0.47 para-aminosalicylic_acid
thyX 3067510 c.436C>T synonymous_variant 0.54 para-aminosalicylic_acid
thyX 3067515 p.Ser144Thr missense_variant 0.54 para-aminosalicylic_acid
thyX 3067611 p.Lys112Thr missense_variant 0.53 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 0.57 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067637 c.309G>A synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067736 c.210C>T synonymous_variant 0.53 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.43 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.43 para-aminosalicylic_acid
thyX 3067772 c.174C>G synonymous_variant 0.38 para-aminosalicylic_acid
thyX 3067775 c.171C>T synonymous_variant 0.38 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.38 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.41 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.37 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.37 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 0.7 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3073866 c.606C>G synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3073872 p.Ile200Val missense_variant 0.8 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.82 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 0.82 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
lpqB 3625543 c.-633G>C upstream_gene_variant 0.57 rifampicin
bedaquiline
mtrB 3625569 c.1045T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625572 p.Thr348Ser missense_variant 0.69 rifampicin
bedaquiline
lpqB 3625579 c.-669A>G upstream_gene_variant 0.71 rifampicin
bedaquiline
lpqB 3625594 c.-684T>C upstream_gene_variant 0.81 rifampicin
bedaquiline
lpqB 3625602 c.-692T>C upstream_gene_variant 0.73 rifampicin
bedaquiline
lpqB 3625612 c.-702G>C upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrB 3625616 p.Arg333Ala missense_variant 0.67 rifampicin
bedaquiline
lpqB 3625624 c.-714C>G upstream_gene_variant 0.73 rifampicin
bedaquiline
mtrB 3625636 c.978C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.82 rifampicin
bedaquiline
lpqB 3625669 c.-759G>C upstream_gene_variant 0.78 rifampicin
bedaquiline
lpqB 3625687 c.-777G>C upstream_gene_variant 0.68 rifampicin
bedaquiline
lpqB 3625690 c.-780T>C upstream_gene_variant 0.67 rifampicin
bedaquiline
lpqB 3625714 c.-804C>T upstream_gene_variant 0.65 rifampicin
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625735 c.-825C>T upstream_gene_variant 0.76 rifampicin
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 0.69 rifampicin Uncertain significance
bedaquiline
mtrB 3625765 c.849C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625774 c.840G>A synonymous_variant 0.75 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625797 p.Val273Met missense_variant 0.81 rifampicin Uncertain significance
bedaquiline Uncertain significance
mtrB 3625806 c.808A>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625807 c.807C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625837 c.777C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626687 c.-74G>T upstream_gene_variant 0.43 rifampicin
bedaquiline
mtrB 3626704 c.-91C>T upstream_gene_variant 0.53 rifampicin
bedaquiline
mtrB 3626711 c.-98T>C upstream_gene_variant 0.53 rifampicin
bedaquiline
mtrA 3626723 c.627C>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626726 c.-113T>C upstream_gene_variant 0.5 rifampicin
bedaquiline
mtrB 3626729 c.-116G>A upstream_gene_variant 0.47 rifampicin
bedaquiline
mtrB 3626732 c.-119A>G upstream_gene_variant 0.56 rifampicin
bedaquiline
mtrA 3626759 c.591T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626774 c.-163_-161delAGGinsCGC upstream_gene_variant 0.61 rifampicin
bedaquiline
mtrB 3626783 c.-170C>G upstream_gene_variant 0.56 rifampicin
bedaquiline
mtrA 3626786 c.564A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626792 c.558G>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626795 c.-182C>T upstream_gene_variant 0.5 rifampicin
bedaquiline
mtrB 3626798 c.-185T>C upstream_gene_variant 0.5 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626957 c.-344G>C upstream_gene_variant 0.43 rifampicin
bedaquiline
mtrB 3626972 c.-359A>G upstream_gene_variant 0.4 rifampicin
bedaquiline
mtrB 3627065 c.-452G>C upstream_gene_variant 0.5 rifampicin
bedaquiline
mtrA 3627068 c.282T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627071 c.279G>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627074 c.-461G>C upstream_gene_variant 0.5 rifampicin
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627083 c.-470G>C upstream_gene_variant 0.5 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627104 c.-491C>G upstream_gene_variant 0.56 rifampicin
bedaquiline
mtrA 3627119 c.231T>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627122 c.-509T>C upstream_gene_variant 0.46 rifampicin
bedaquiline
mtrB 3627167 c.-554T>C upstream_gene_variant 0.8 rifampicin
bedaquiline
mtrA 3627188 c.162A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627209 c.-596G>A upstream_gene_variant 0.85 rifampicin
bedaquiline
mtrA 3627221 c.129C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627227 c.123T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627233 c.-620T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627236 c.-623T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627242 c.108C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627254 c.-641C>T upstream_gene_variant 0.93 rifampicin
bedaquiline
mtrB 3627263 c.-650C>T upstream_gene_variant 0.76 rifampicin
bedaquiline
mtrB 3627266 c.-653A>G upstream_gene_variant 0.72 rifampicin
bedaquiline
mtrB 3627272 c.-659G>T upstream_gene_variant 0.75 rifampicin
bedaquiline
mtrB 3627275 c.-662G>T upstream_gene_variant 0.74 rifampicin
bedaquiline
mtrB 3627296 c.-683T>C upstream_gene_variant 0.68 rifampicin
bedaquiline
mtrB 3627299 c.-688_-686delTTGinsCTA upstream_gene_variant 0.68 rifampicin
bedaquiline
mtrB 3627314 c.-701C>T upstream_gene_variant 0.62 rifampicin
bedaquiline
mtrB 3627317 c.-704T>C upstream_gene_variant 0.61 rifampicin
bedaquiline
mtrA 3627343 p.Thr3Ser missense_variant 0.48 rifampicin
bedaquiline
mtrB 3627360 c.-747G>C upstream_gene_variant 0.39 rifampicin
bedaquiline
rpoA 3877553 p.Glu319Gln missense_variant 0.47 rifampicin
rpoA 3877571 p.Pro313Ala missense_variant 0.48 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.8 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.83 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3877791 c.717C>G synonymous_variant 0.57 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.5 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.54 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 0.57 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 0.57 rifampicin
rpoA 3877890 c.618C>T synonymous_variant 0.54 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.5 rifampicin
rpoA 3877900 p.Ser203Asn missense_variant 0.53 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 0.5 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3878130 c.378C>G synonymous_variant 0.5 rifampicin
rpoA 3878141 p.Met123Leu missense_variant 0.54 rifampicin Uncertain significance
rpoA 3878143 p.Gly122Asp missense_variant 0.58 rifampicin Uncertain significance
rpoA 3878157 c.351C>G synonymous_variant 0.73 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoA 3878226 c.282C>G synonymous_variant 0.59 rifampicin
rpoA 3878232 c.276G>C synonymous_variant 0.53 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.5 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoA 3878284 p.Glu75Ala missense_variant 0.5 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.48 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.52 rifampicin
rpoA 3878364 c.144A>T synonymous_variant 0.53 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.56 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 0.63 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.56 rifampicin
rpoA 3878388 c.120C>G synonymous_variant 0.67 rifampicin
rpoA 3878391 c.117T>C synonymous_variant 0.67 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.67 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.76 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.7 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.67 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 0.57 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.55 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.46 rifampicin Uncertain significance
rpoA 3878986 c.-479G>C upstream_gene_variant 0.67 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.64 rifampicin Uncertain significance
rpoA 3879005 c.-499_-498delAAinsCG upstream_gene_variant 0.71 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 0.69 rifampicin
clpC1 4038293 c.2412G>C synonymous_variant 0.67 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.67 pyrazinamide
clpC1 4038308 c.2397G>T synonymous_variant 0.69 pyrazinamide
clpC1 4038314 c.2391T>C synonymous_variant 0.67 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.67 pyrazinamide
clpC1 4038320 c.2385G>T synonymous_variant 0.67 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.71 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.71 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.71 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.62 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 0.62 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.54 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
clpC1 4038530 p.Glu725Asp missense_variant 0.57 pyrazinamide
clpC1 4038541 c.2164C>T synonymous_variant 0.54 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.57 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.45 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.5 pyrazinamide
clpC1 4038749 c.1956C>G synonymous_variant 0.58 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.58 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.73 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.67 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.64 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.67 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.73 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.75 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.77 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.75 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.76 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.81 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.8 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.79 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.79 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.77 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.79 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.8 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.82 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.78 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.78 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.76 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.76 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.76 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.8 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 0.81 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
clpC1 4039229 c.1476C>G synonymous_variant 0.71 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.75 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 0.62 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.64 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.5 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 0.55 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 0.6 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 0.6 pyrazinamide
clpC1 4039349 c.1356C>T synonymous_variant 0.6 pyrazinamide
clpC1 4039352 c.1353C>G synonymous_variant 0.6 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 0.64 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.44 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.4 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.38 pyrazinamide
clpC1 4039565 c.1140G>T synonymous_variant 0.38 pyrazinamide
clpC1 4039576 p.Ala377Pro missense_variant 0.47 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.44 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.53 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.47 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.56 pyrazinamide
clpC1 4039661 c.1044T>G synonymous_variant 0.76 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.76 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.67 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.73 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.67 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.53 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.56 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.63 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 0.65 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.67 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.72 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.76 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.76 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.75 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.7 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4040171 c.534C>G synonymous_variant 0.43 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.37 pyrazinamide
panD 4044872 c.-591C>T upstream_gene_variant 1.0 pyrazinamide
panD 4045019 c.-738G>C upstream_gene_variant 0.5 pyrazinamide
panD 4045022 c.-741C>G upstream_gene_variant 0.54 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 0.58 pyrazinamide
panD 4045034 c.-753A>C upstream_gene_variant 0.47 pyrazinamide
panD 4045055 c.-774T>G upstream_gene_variant 0.5 pyrazinamide
panD 4045067 c.-786C>G upstream_gene_variant 0.46 pyrazinamide
panD 4045070 c.-789C>T upstream_gene_variant 0.46 pyrazinamide
panD 4045076 c.-795A>C upstream_gene_variant 0.46 pyrazinamide
panD 4045088 c.-807T>C upstream_gene_variant 0.43 pyrazinamide
glpK 4139143 c.613T>C synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139165 c.591A>G synonymous_variant 0.62 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139168 c.588T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139177 c.579T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139183 c.573T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139186 c.570G>C synonymous_variant 0.73 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139195 c.561G>T synonymous_variant 0.73 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.69 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.64 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.62 ethambutol
embC 4240819 c.957A>G synonymous_variant 0.58 ethambutol
embC 4240828 c.966G>A synonymous_variant 0.53 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.53 ethambutol
embC 4240867 c.1005T>C synonymous_variant 0.37 ethambutol
embC 4241053 c.1191G>C synonymous_variant 0.69 ethambutol
embC 4241089 c.1227C>G synonymous_variant 0.7 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.68 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.67 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.65 ethambutol Not assoc w R - Interim
embC 4241146 c.1284C>G synonymous_variant 0.65 ethambutol
embC 4241158 c.1296T>C synonymous_variant 0.68 ethambutol
embC 4241161 c.1299C>G synonymous_variant 0.69 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 0.65 ethambutol
embC 4241170 c.1308G>C synonymous_variant 0.65 ethambutol
embC 4241173 c.1311C>T synonymous_variant 0.69 ethambutol
embC 4241203 c.1341T>C synonymous_variant 0.69 ethambutol
embC 4241206 c.1344G>C synonymous_variant 0.69 ethambutol Not assoc w R - Interim
embC 4241218 c.1356G>C synonymous_variant 0.58 ethambutol
embC 4241374 c.1512T>C synonymous_variant 0.55 ethambutol
embC 4241380 c.1518A>C synonymous_variant 0.55 ethambutol
embC 4241394 p.Lys511Ser missense_variant 0.6 ethambutol
embC 4241567 p.Ile569Val missense_variant 0.5 ethambutol
embC 4241572 c.1710C>G synonymous_variant 0.56 ethambutol
embC 4241578 c.1716G>C synonymous_variant 0.5 ethambutol
embC 4241584 c.1722T>C synonymous_variant 0.5 ethambutol
embC 4241587 c.1725C>G synonymous_variant 0.53 ethambutol
embC 4241591 p.Leu577Val missense_variant 0.5 ethambutol
embC 4241611 c.1749G>C synonymous_variant 0.5 ethambutol
embC 4241614 c.1752A>C synonymous_variant 0.47 ethambutol
embC 4241626 c.1764T>C synonymous_variant 0.44 ethambutol
embC 4241635 c.1773G>C synonymous_variant 0.41 ethambutol
embC 4242643 c.2781C>T synonymous_variant 0.91 ethambutol Not assoc w R
embA 4245137 c.1905T>C synonymous_variant 0.35 ethambutol
embA 4245146 c.1914G>A synonymous_variant 0.33 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.35 ethambutol
embA 4245153 p.Ile641Val missense_variant 0.35 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.33 ethambutol
embA 4245189 c.1957C>T synonymous_variant 0.3 ethambutol
embA 4245198 p.Leu656Ile missense_variant 0.3 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.3 ethambutol
embA 4246235 c.3003G>A synonymous_variant 0.43 ethambutol Not assoc w R - Interim
embA 4246242 p.Gln1004Gly missense_variant 0.4 ethambutol
embB 4246250 c.-264G>C upstream_gene_variant 0.44 ethambutol
embB 4246256 c.-258G>T upstream_gene_variant 0.47 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 0.5 ethambutol
embA 4246264 p.His1011Arg missense_variant 0.5 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 0.5 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 0.5 ethambutol
embA 4246308 p.Thr1026Ala missense_variant 0.5 ethambutol
embB 4246316 c.-198T>G upstream_gene_variant 0.5 ethambutol
embB 4246319 c.-195G>C upstream_gene_variant 0.5 ethambutol
embB 4247539 c.1026T>C synonymous_variant 0.58 ethambutol
embB 4247940 p.Leu476Trp missense_variant 0.64 ethambutol
embB 4247945 c.1432T>C synonymous_variant 0.6 ethambutol
embB 4247951 p.Ser480Ala missense_variant 0.6 ethambutol
embB 4247956 c.1443G>C synonymous_variant 0.6 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 0.5 ethambutol
embB 4248220 c.1707A>C synonymous_variant 0.37 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.38 ethambutol
embB 4249498 c.2985G>C synonymous_variant 0.62 ethambutol
embB 4249521 p.Ala1003Val missense_variant 0.62 ethambutol
embB 4249525 c.3012T>C synonymous_variant 0.6 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.56 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 0.56 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 0.56 ethambutol
embB 4249543 c.3030G>C synonymous_variant 0.53 ethambutol
embB 4249546 c.3033G>A synonymous_variant 0.53 ethambutol
aftB 4268129 c.708T>G synonymous_variant 0.55 ethambutol
aftB 4268138 c.699A>C synonymous_variant 0.55 ethambutol Not assoc w R - Interim
aftB 4268144 c.693T>C synonymous_variant 0.54 ethambutol
aftB 4268164 p.Gln225Glu missense_variant 0.6 ethambutol
aftB 4268169 p.Ala223Gly missense_variant 0.58 ethambutol
aftB 4268171 c.666G>C synonymous_variant 0.54 ethambutol
aftB 4268179 c.658T>C synonymous_variant 0.46 ethambutol Not assoc w R - Interim
aftB 4268182 p.Phe219Leu missense_variant 0.43 ethambutol
aftB 4268183 c.654A>T synonymous_variant 0.43 ethambutol
aftB 4268193 p.Leu215Ala missense_variant 0.46 ethambutol
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin