TB-Profiler result

Run: ERR2513121
Summary

Run ID: ERR2513121

Sample name:

Date: 2025-09-15T14:07:34.026622

Number of reads: 1658248

Percentage reads mapped: 73.65

Median coverage: 51.0

Strain: lineage3.1.3

Spoligotype:

Drug-resistance: Sensitive

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage3 East-African-Indian RD750 100.0
lineage3.1.3 East-African-Indian RD750 100.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 6242 p.Arg335Lys missense_variant 0.24 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6250 c.1011A>T synonymous_variant 0.22 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6253 c.1014G>C synonymous_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6265 c.1026C>T synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6268 c.1029C>G synonymous_variant 0.22 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6280 c.1041T>C synonymous_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6286 c.1047T>C synonymous_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6292 c.1053G>T synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6727 c.-575G>T upstream_gene_variant 0.13 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6730 c.-572A>G upstream_gene_variant 0.12 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7424 c.123G>A synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7433 c.132G>C synonymous_variant 0.23 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7436 c.135C>T synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7442 c.141G>C synonymous_variant 0.23 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7457 c.156T>C synonymous_variant 0.26 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7460 c.159C>G synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7463 c.162G>C synonymous_variant 0.26 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7472 c.171T>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
gyrA 7475 c.174A>G synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.25 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7484 c.183T>C synonymous_variant 0.24 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7487 c.186C>G synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7499 c.198G>A synonymous_variant 0.3 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7523 c.222C>A synonymous_variant 0.32 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7526 c.225G>T synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.26 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7569 p.Ala90Ser missense_variant 0.22 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7886 c.585T>C synonymous_variant 0.13 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7889 c.588G>A synonymous_variant 0.12 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7890 c.589C>T synonymous_variant 0.12 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7898 p.Asp199Glu missense_variant 0.13 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8375 c.1074G>C synonymous_variant 0.13 levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
gyrA 8471 c.1170T>C synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8477 c.1176C>T synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8486 c.1185T>G synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8489 c.1188A>G synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8501 c.1200G>A synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8504 c.1203G>C synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8513 c.1212C>G synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8519 c.1218A>C synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8520 c.1219C>T synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8528 c.1227G>C synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8535 p.Glu412Gln missense_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8540 c.1239C>G synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 p.Asp415Glu missense_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8555 c.1254G>C synonymous_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8561 c.1260A>C synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8942 c.1641G>A synonymous_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8946 c.1645T>C synonymous_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8952 p.Gln551Ala missense_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8967 p.Ala556Asn missense_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8981 c.1680G>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8996 c.1695T>C synonymous_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8998 p.Leu566Trp missense_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
fgd1 491742 c.960T>C synonymous_variant 1.0 clofazimine Not assoc w R
delamanid Not assoc w R - Interim
pretomanid Uncertain significance
Rv0565c 657081 c.390G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
rpoB 760151 c.345G>A synonymous_variant 0.13 rifampicin Uncertain significance
rpoB 760196 c.390C>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 760316 c.510C>G synonymous_variant 0.18 rifampicin Uncertain significance
rpoB 760325 c.519G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760331 c.525G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 760334 c.528G>T synonymous_variant 0.2 rifampicin Uncertain significance
rpoB 760340 c.534G>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 0.26 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.26 rifampicin Uncertain significance
rpoB 760376 p.Asp190Glu missense_variant 0.25 rifampicin Uncertain significance
rpoB 760407 p.Ser201Gly missense_variant 0.22 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 761027 c.1221A>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 761234 c.1428G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 761948 c.2142G>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.22 rifampicin Uncertain significance
rpoB 762002 c.2196C>G synonymous_variant 0.22 rifampicin Uncertain significance
rpoB 762038 c.2232C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.23 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.24 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.18 rifampicin Uncertain significance
rpoB 762137 c.2331C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 762143 c.2337T>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoB 762149 c.2343G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762239 c.2433G>A synonymous_variant 0.22 rifampicin Uncertain significance
rpoB 762245 c.2439G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>T synonymous_variant 0.27 rifampicin Uncertain significance
rpoB 762293 c.2487T>G synonymous_variant 0.26 rifampicin Uncertain significance
rpoB 762347 c.2541T>C synonymous_variant 0.24 rifampicin Uncertain significance
rpoB 762353 c.2547C>T synonymous_variant 0.26 rifampicin Uncertain significance
rpoB 762362 p.Glu852Asp missense_variant 0.27 rifampicin Uncertain significance
rpoB 762369 c.2563T>C synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 762374 c.-996G>C upstream_gene_variant 0.29 rifampicin Uncertain significance
rpoC 762380 c.-990T>C upstream_gene_variant 0.29 rifampicin Uncertain significance
rpoC 762395 c.-975G>C upstream_gene_variant 0.22 rifampicin Uncertain significance
rpoC 762398 c.-972T>C upstream_gene_variant 0.21 rifampicin Uncertain significance
rpoC 762401 c.-969G>C upstream_gene_variant 0.19 rifampicin Uncertain significance
rpoB 762404 c.2598T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.28 rifampicin Uncertain significance
rpoB 762416 c.2610A>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762434 c.2628T>G synonymous_variant 0.72 rifampicin Not assoc w R
rpoC 762443 c.-927G>C upstream_gene_variant 0.3 rifampicin Uncertain significance
rpoB 762449 c.2643C>A synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 0.15 rifampicin Uncertain significance
rpoC 762911 c.-459C>T upstream_gene_variant 0.22 rifampicin Uncertain significance
rpoB 762920 c.3114C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.26 rifampicin Uncertain significance
rpoB 762989 c.3183G>A synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763022 c.-348C>G upstream_gene_variant 0.26 rifampicin Uncertain significance
rpoB 763028 c.3222T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.75 rifampicin Not assoc w R
rpoB 763053 c.3247T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 0.33 rifampicin Uncertain significance
rpoB 763088 c.3282C>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>C upstream_gene_variant 0.3 rifampicin Uncertain significance
rpoB 763115 c.3309T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.25 rifampicin Uncertain significance
rpoB 763136 c.3330C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763160 c.-210G>T upstream_gene_variant 0.26 rifampicin Uncertain significance
rpoB 763166 c.3360A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.24 rifampicin Uncertain significance
rpoC 763193 c.-177C>T upstream_gene_variant 0.18 rifampicin Uncertain significance
rpoC 763202 c.-168A>C upstream_gene_variant 0.16 rifampicin Uncertain significance
rpoC 763205 c.-165G>C upstream_gene_variant 0.15 rifampicin Uncertain significance
rpoC 763208 c.-162T>C upstream_gene_variant 0.14 rifampicin Uncertain significance
rpoB 763214 c.3408T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 763465 c.96G>A synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 763468 c.99G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.22 rifampicin Uncertain significance
rpoC 763492 c.123G>T synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 763528 c.159G>A synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 0.22 rifampicin Uncertain significance
rpoC 763594 c.225C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763621 c.252C>G synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 763741 c.372C>T synonymous_variant 0.12 rifampicin Uncertain significance
rpoC 763747 c.378G>A synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 763781 p.Ser138Ala missense_variant 0.14 rifampicin Uncertain significance
rpoC 763792 p.Glu141Asp missense_variant 0.16 rifampicin Uncertain significance
rpoC 763807 c.438T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 763816 c.447C>G synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 763831 c.462A>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 763837 c.468G>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 763840 c.471G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 764254 c.885G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 764263 c.894G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 764266 c.897T>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 764272 c.903G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 764278 c.909A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764297 p.Met310Leu missense_variant 0.23 rifampicin Uncertain significance
rpoC 764344 c.975C>T synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 764353 c.984G>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764374 c.1005C>T synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 764380 c.1011G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764623 c.1254C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764692 c.1323C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764719 c.1350G>A synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 764746 c.1377G>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.13 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 764851 c.1482C>T synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 764858 c.1489T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 0.13 rifampicin Uncertain significance
rpoC 765466 c.2097C>T synonymous_variant 0.13 rifampicin Uncertain significance
rpoC 765835 c.2466C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 765886 c.2517C>G synonymous_variant 0.13 rifampicin Uncertain significance
rpoC 767068 c.3699G>T synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 767098 c.3729T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 767105 p.Asn1246Gln missense_variant 0.14 rifampicin Uncertain significance
rpoC 767119 c.3750A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 767162 p.Asn1265Ala missense_variant 0.15 rifampicin Uncertain significance
rpoC 767167 c.3798C>T synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 767174 p.Asn1269Asp missense_variant 0.15 rifampicin Uncertain significance
rpoC 767180 p.Ala1271Gln missense_variant 0.15 rifampicin Uncertain significance
rpoC 767191 c.3822C>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.13 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 776100 p.Thr794Ile missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781814 c.255C>T synonymous_variant 0.14 streptomycin Uncertain significance
rpsL 781829 c.270G>T synonymous_variant 0.16 streptomycin Uncertain significance
rpsL 781832 c.273T>G synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781838 c.279G>C synonymous_variant 0.16 streptomycin Uncertain significance
rpsL 781841 c.282C>T synonymous_variant 0.16 streptomycin Uncertain significance
rpsL 781859 c.300T>G synonymous_variant 0.16 streptomycin Uncertain significance
rpsL 781868 c.309T>C synonymous_variant 0.17 streptomycin Uncertain significance
rpsL 781871 c.312G>C synonymous_variant 0.17 streptomycin Uncertain significance
rpsL 781877 c.318T>C synonymous_variant 0.19 streptomycin Uncertain significance
rpsL 781892 c.333A>G synonymous_variant 0.17 streptomycin Uncertain significance
rpsL 781898 c.339A>C synonymous_variant 0.16 streptomycin Uncertain significance
rpsL 781901 c.342C>T synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781907 c.348T>C synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781916 c.357T>C synonymous_variant 0.16 streptomycin Uncertain significance
rpsL 781929 p.Gly124Ser missense_variant 0.14 streptomycin Uncertain significance
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 isoniazid Not assoc w R
levofloxacin Not assoc w R
moxifloxacin Not assoc w R
rifampicin Not assoc w R
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.2 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.22 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.22 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472028 n.183A>G non_coding_transcript_exon_variant 0.21 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.21 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472032 n.187G>A non_coding_transcript_exon_variant 0.21 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.22 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.25 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472037 n.192A>C non_coding_transcript_exon_variant 0.23 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.23 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.23 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.23 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.23 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.24 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.34 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.41 amikacin Not assoc w R
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.42 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.4 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.36 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.5 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.56 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.57 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.57 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.47 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.51 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472848 n.1003T>A non_coding_transcript_exon_variant 0.5 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.5 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.49 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 0.49 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.48 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472953 n.1108G>A non_coding_transcript_exon_variant 0.49 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.48 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.47 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.47 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.51 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.49 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.49 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 0.48 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.5 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.47 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.51 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.49 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474091 n.434C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474096 n.439C>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474102 n.445_446insTGAAC non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474106 n.449_453delATCAAinsG non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474287 n.630_646delTCCTTTTCCTCTCCGGAinsCTCGACTTT non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474305 n.648G>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474439 n.782A>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053T>A non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474711 n.1054G>C non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474712 n.1055G>A non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474713 n.1056T>A non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474716 n.1059_1063delAAAGCinsCCAAGAAT non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475603 n.1946G>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475615 n.1958C>G non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475618 n.1961C>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475626 n.1969delTinsCC non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475629 n.1972G>C non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.37 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.51 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.42 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.41 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833694 c.153G>C synonymous_variant 0.13 pyrazinamide Uncertain significance
rpsA 1833709 c.168C>T synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1833724 c.183C>T synonymous_variant 0.13 pyrazinamide Uncertain significance
rpsA 1833727 c.186G>C synonymous_variant 0.13 pyrazinamide Uncertain significance
rpsA 1833730 c.189C>T synonymous_variant 0.13 pyrazinamide Uncertain significance
rpsA 1833734 p.Ala65Ser missense_variant 0.13 pyrazinamide Uncertain significance
rpsA 1833745 c.204G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1833760 c.219C>T synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1833790 c.249T>C synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1833793 c.252C>T synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1833802 c.261A>G synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1833808 c.267G>C synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1833811 c.270G>T synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1833829 c.288A>G synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1833832 c.291G>A synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1833838 c.297G>C synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1833841 c.300C>G synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1833847 c.306C>G synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1833856 c.315A>G synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1833862 c.321G>T synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1833894 p.Ala118Glu missense_variant 0.14 pyrazinamide Uncertain significance
rpsA 1833928 c.387G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1833976 c.435C>T synonymous_variant 0.12 pyrazinamide Uncertain significance
rpsA 1834012 c.471G>T synonymous_variant 0.13 pyrazinamide Uncertain significance
rpsA 1834015 c.474G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834021 c.480C>T synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834030 c.489C>G synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1834102 c.561T>C synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834150 c.609G>C synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1834153 c.612T>C synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1834154 p.Asn205Gln missense_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834157 c.616_618delTTGinsCTA synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1834162 c.621A>G synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1834168 c.627C>T synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
rpsA 1834169 p.Thr210Ala missense_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
rpsA 1834213 c.672G>C synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1834231 c.690T>C synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834234 c.693G>C synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834240 c.699T>C synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834249 c.708T>C synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834261 c.720A>G synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834279 c.738C>T synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 0.13 pyrazinamide Uncertain significance
rpsA 1834348 c.807T>C synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1834366 c.825A>G synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1834411 c.870T>C synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1834423 c.882G>T synonymous_variant 0.28 pyrazinamide Uncertain significance
rpsA 1834451 c.910T>C synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834456 c.915T>G synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834468 c.927A>G synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834489 c.948T>C synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834498 c.957C>T synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834513 c.972C>G synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834520 p.Ala327Ser missense_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834528 c.987T>C synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1834540 c.999G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834543 c.1002C>G synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834546 c.1005T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.14 pyrazinamide Uncertain significance
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1918474 p.Pro179Ser missense_variant 1.0 capreomycin Uncertain significance
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Not assoc w R
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Not assoc w R
Rv1979c 2222732 c.432delT frameshift_variant 1.0 bedaquiline Uncertain significance
clofazimine Uncertain significance
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
pncA 2289365 c.-125delC upstream_gene_variant 1.0 pyrazinamide Uncertain significance
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0 isoniazid Not assoc w R
Rv2477c 2782498 c.1545C>T synonymous_variant 1.0 amikacin Not assoc w R
ethambutol Not assoc w R
kanamycin Not assoc w R
levofloxacin Not assoc w R
moxifloxacin Not assoc w R
rifampicin Not assoc w R
streptomycin Not assoc w R - Interim
Rv2752c 3066008 p.Pro62Ser missense_variant 0.93 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine Uncertain significance
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
rpoA 3877887 c.621G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3877893 c.615C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3877905 c.603A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoA 3877962 c.546G>T synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoA 3877965 c.543C>G synonymous_variant 0.15 rifampicin Uncertain significance
rpoA 3877971 p.Asp179Glu missense_variant 0.14 rifampicin Uncertain significance
rpoA 3878143 p.Gly122Asp missense_variant 0.13 rifampicin Uncertain significance
rpoA 3878145 c.363C>G synonymous_variant 0.14 rifampicin Uncertain significance
rpoA 3878157 c.351C>G synonymous_variant 0.14 rifampicin Uncertain significance
rpoA 3878160 c.348C>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoA 3878184 c.324C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3878271 c.237T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
clpC1 4038519 p.Arg729Gln missense_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038623 c.2082A>G synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4038640 p.Asp689Asn missense_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038647 c.2058T>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038653 c.2052C>T synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038695 c.2010C>G synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4038721 c.1984C>T synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4038725 c.1980C>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038740 c.1965G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038767 c.1938G>C synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4038770 c.1935C>T synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4038773 c.1932T>C synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4038776 c.1929G>A synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4038779 c.1926C>G synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4038782 c.1923G>C synonymous_variant 0.12 pyrazinamide Uncertain significance
clpC1 4038790 c.1915C>T synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4038815 c.1890G>T synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4038842 c.1863G>C synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4038878 c.1827A>G synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4038884 c.1821C>T synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4038890 c.1815G>A synonymous_variant 0.3 pyrazinamide Uncertain significance
clpC1 4038905 c.1800A>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4038908 c.1797C>G synonymous_variant 0.26 pyrazinamide Uncertain significance
clpC1 4038911 c.1794G>T synonymous_variant 0.26 pyrazinamide Uncertain significance
clpC1 4038914 c.1791G>C synonymous_variant 0.26 pyrazinamide Uncertain significance
clpC1 4038917 c.1788C>T synonymous_variant 0.26 pyrazinamide Uncertain significance
clpC1 4038923 c.1782A>G synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4038941 c.1764G>C synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4038953 c.1752A>G synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4038956 c.1749T>C synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4038965 c.1740T>C synonymous_variant 0.29 pyrazinamide Uncertain significance
clpC1 4038971 c.1734T>C synonymous_variant 0.29 pyrazinamide Uncertain significance
clpC1 4038974 c.1731T>C synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4038997 c.1708T>C synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 0.26 pyrazinamide Uncertain significance
clpC1 4039064 c.1641C>T synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039067 c.1638G>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039079 c.1626C>G synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039091 c.1614G>T synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039097 c.1608G>T synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4039106 c.1599G>T synonymous_variant 0.26 pyrazinamide Uncertain significance
clpC1 4039109 c.1596C>T synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4039112 c.1593C>G synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4039121 c.1584T>C synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4039142 c.1563A>G synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039145 c.1560G>C synonymous_variant 0.26 pyrazinamide Uncertain significance
clpC1 4039169 p.Glu512Asp missense_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039172 c.1533A>G synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039178 c.1527G>C synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039183 c.1522T>C synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039187 c.1518G>C synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039190 c.1515C>G synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039208 c.1497C>G synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4039220 c.1485G>C synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039226 c.1479T>C synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
clpC1 4039241 c.1464G>C synonymous_variant 0.26 pyrazinamide Uncertain significance
clpC1 4039592 c.1113G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039610 c.1095G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039622 c.1083C>T synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039649 c.1056G>C synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039673 c.1032G>A synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039682 c.1023C>G synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039685 c.1020C>T synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039694 c.1011G>T synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039724 c.981A>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039733 c.972G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040444 c.261C>G synonymous_variant 0.13 pyrazinamide Uncertain significance
panD 4044872 c.-591C>T upstream_gene_variant 1.0 pyrazinamide Uncertain significance
glpK 4138703 c.1053C>G synonymous_variant 0.24 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138709 c.1047G>C synonymous_variant 0.27 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138718 c.1038T>C synonymous_variant 0.3 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138727 c.1029C>G synonymous_variant 0.31 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138730 c.1026C>T synonymous_variant 0.33 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138757 c.999A>G synonymous_variant 0.28 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138775 c.981C>T synonymous_variant 0.16 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138784 c.972G>C synonymous_variant 0.15 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
embC 4242075 p.Arg738Gln missense_variant 1.0 ethambutol Not assoc w R
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4249195 c.2682C>A synonymous_variant 1.0 ethambutol Not assoc w R
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
gid 4407588 c.615A>G synonymous_variant 1.0 streptomycin Not assoc w R
gid 4408175 p.Ala10Pro missense_variant 1.0 streptomycin Uncertain significance