Run ID: ERR4769418
Sample name:
Date: 2024-10-04T19:06:06.574318
Number of reads: 2000035
Percentage reads mapped: 50.08
Median coverage: 60.0
Strain: La1.2
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|---|---|---|
La1.2 | M.bovis | None | 0.99 |
La1 | M.bovis | None | 1.0 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | ||||
pyrazinamide | pncA | p.His57Asp | Assoc w R | |
streptomycin | rrs | n.799C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rrs | 1472644 | n.799C>T | non_coding_transcript_exon_variant | 0.81 | streptomycin | Uncertain significance | Mutation from literature |
pncA | 2289073 | p.His57Asp | missense_variant | 1.0 | pyrazinamide | Assoc w R |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 467 | p.His156Arg | missense_variant | 1.0 | isoniazid | Not assoc w R |
gyrB | 5752 | c.513G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6406 | c.1167C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6446 | p.Ala403Ser | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Uncertain significance | |||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7821 | c.520C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8285 | c.984C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8741 | c.1440C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9143 | c.1842T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
Rv0010c | 13197 | p.Thr121Ser | missense_variant | 1.0 | isoniazid | Not assoc w R |
Rv0010c | 13228 | c.330delG | frameshift_variant | 1.0 | isoniazid | Uncertain significance |
Rv0010c | 13280 | c.279C>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
Rv0010c | 13460 | c.99T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R |
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R | |||||
Rv0565c | 657578 | c.-108T>C | upstream_gene_variant | 1.0 | ethionamide | |
rpoB | 761998 | c.2193_2195delGTC | disruptive_inframe_deletion | 0.16 | rifampicin | |
rpoB | 762005 | c.2200_2201insAGC | disruptive_inframe_insertion | 0.16 | rifampicin | |
rpoB | 762008 | c.2202C>T | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 762009 | p.Leu735Val | missense_variant | 0.16 | rifampicin | |
rpoB | 762014 | c.2208C>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 762024 | p.Val740Ile | missense_variant | 0.16 | rifampicin | |
rpoB | 762035 | c.2229G>C | synonymous_variant | 0.16 | rifampicin | |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 762080 | c.2274G>C | synonymous_variant | 0.16 | rifampicin | |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 762092 | c.2286G>A | synonymous_variant | 0.16 | rifampicin | |
rpoB | 762098 | c.2292C>T | synonymous_variant | 0.14 | rifampicin | |
rpoB | 762101 | c.2295C>T | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 762104 | p.Asp766Glu | missense_variant | 0.14 | rifampicin | |
rpoB | 762887 | c.3081G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 762905 | p.Asp1033Glu | missense_variant | 0.26 | rifampicin | |
rpoC | 762923 | c.-447C>T | upstream_gene_variant | 0.37 | rifampicin | |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 762938 | c.-432G>C | upstream_gene_variant | 0.4 | rifampicin | |
rpoB | 762959 | c.3153G>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 762971 | c.-399G>C | upstream_gene_variant | 0.48 | rifampicin | |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.54 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 763005 | p.Cys1067Val | missense_variant | 0.5 | rifampicin | |
rpoC | 763013 | c.-357C>A | upstream_gene_variant | 0.52 | rifampicin | |
rpoC | 763022 | c.-348C>A | upstream_gene_variant | 0.53 | rifampicin | |
rpoC | 763025 | c.-345C>T | upstream_gene_variant | 0.54 | rifampicin | |
rpoB | 763031 | c.3225T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 763052 | c.-318G>T | upstream_gene_variant | 0.5 | rifampicin | |
rpoB | 763053 | c.3247T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 763074 | p.Thr1090Val | missense_variant | 0.45 | rifampicin | |
rpoB | 763085 | c.3279C>T | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 763094 | c.3288G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 763103 | c.-267G>A | upstream_gene_variant | 0.4 | rifampicin | |
rpoC | 763109 | c.-261C>T | upstream_gene_variant | 0.4 | rifampicin | |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 763130 | p.Glu1108Asp | missense_variant | 0.33 | rifampicin | |
rpoB | 763136 | c.3330C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.24 | rifampicin | |
rpoB | 763157 | c.3351G>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 763160 | c.-210G>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 763169 | c.-201A>G | upstream_gene_variant | 0.17 | rifampicin | |
rpoC | 763178 | c.-192G>C | upstream_gene_variant | 0.13 | rifampicin | |
rpoC | 763468 | c.99G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763471 | c.102C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763483 | c.114G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763486 | c.117T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763507 | c.138G>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763517 | p.Lys50Arg | missense_variant | 0.24 | rifampicin | |
rpoC | 763528 | c.159G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763531 | c.162G>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763534 | c.165T>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763549 | c.180C>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 763550 | p.Tyr61Ala | missense_variant | 0.21 | rifampicin | |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 763576 | c.207C>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 763578 | p.Phe70Tyr | missense_variant | 0.28 | rifampicin | |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763619 | p.Arg84Lys | missense_variant | 0.17 | rifampicin | |
rpoC | 763622 | p.Ala85Ser | missense_variant | 0.17 | rifampicin | Uncertain significance |
rpoC | 763630 | c.261G>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 763633 | c.264T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 763642 | c.273G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 763666 | c.297G>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 763669 | c.300C>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764371 | c.1002G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764398 | c.1029G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764404 | c.1035C>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036_1038delAGGinsCGT | synonymous_variant | 0.2 | rifampicin | |
rpoC | 764428 | c.1059G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764435 | c.1066_1068delAGGinsCGC | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764438 | p.Leu357Met | missense_variant | 0.22 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764455 | c.1086G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764458 | c.1089G>T | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764470 | c.1101C>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764485 | c.1116G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764503 | c.1134G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764509 | c.1140G>T | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764512 | c.1143G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764524 | c.1155C>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764548 | c.1179G>A | synonymous_variant | 0.39 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 764578 | c.1209C>T | synonymous_variant | 0.44 | rifampicin | |
rpoC | 764581 | c.1212T>C | synonymous_variant | 0.45 | rifampicin | |
rpoC | 764602 | c.1233C>T | synonymous_variant | 0.5 | rifampicin | |
rpoC | 764605 | c.1236G>T | synonymous_variant | 0.5 | rifampicin | |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 764623 | c.1254C>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 764626 | c.1257C>T | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764632 | c.1263T>A | synonymous_variant | 0.42 | rifampicin | |
rpoC | 764644 | c.1275G>T | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 764659 | c.1290C>T | synonymous_variant | 0.38 | rifampicin | |
rpoC | 764660 | p.Val431Ile | missense_variant | 0.38 | rifampicin | |
rpoC | 764687 | p.Gln440Glu | missense_variant | 0.35 | rifampicin | |
rpoC | 764692 | c.1323C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764701 | c.1332C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764707 | c.1338G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764713 | c.1344G>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764716 | c.1347G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764746 | c.1377G>A | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764754 | c.1386_1389delCCTC | frameshift_variant | 0.17 | rifampicin | |
rpoC | 764761 | p.Asn464Lys | missense_variant | 0.16 | rifampicin | |
rpoC | 764763 | c.1394_1395delATinsGAGTAC | frameshift_variant&missense_variant | 0.16 | rifampicin | |
rpoC | 764780 | c.1411_1412delAGinsTC | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764785 | c.1416C>T | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764797 | c.1428G>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764800 | c.1431G>A | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764803 | c.1434C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R |
rpoC | 764813 | p.Gln482Glu | missense_variant | 0.27 | rifampicin | |
rpoC | 764824 | c.1455T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764833 | c.1464A>G | synonymous_variant | 0.34 | rifampicin | |
rpoC | 764838 | p.Val490Ala | missense_variant | 0.38 | rifampicin | |
rpoC | 764843 | p.Ala492Ser | missense_variant | 0.4 | rifampicin | |
rpoC | 764857 | c.1488G>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 764858 | p.Leu497Met | missense_variant | 0.37 | rifampicin | |
rpoC | 764863 | c.1494G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764869 | c.1500C>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764875 | c.1506C>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 764887 | c.1518G>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 764913 | p.Met515Lys | missense_variant | 0.34 | rifampicin | |
rpoC | 764917 | c.1548G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764920 | c.1551G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764923 | c.1554A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764926 | c.1557C>T | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764948 | c.1579_1581delTTGinsCTC | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764952 | p.Val528Ala | missense_variant | 0.3 | rifampicin | |
rpoC | 764959 | c.1590G>A | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764962 | c.1593G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 767008 | c.3639G>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 767017 | c.3648C>T | synonymous_variant | 0.15 | rifampicin | |
rpoC | 767023 | p.Asp1218Glu | missense_variant | 0.15 | rifampicin | |
rpoC | 767026 | c.3657G>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 767035 | c.3666G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 767038 | c.3669G>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 767041 | c.3672G>A | synonymous_variant | 0.18 | rifampicin | |
rpoC | 767062 | c.3693C>T | synonymous_variant | 0.17 | rifampicin | |
rpoC | 767065 | c.3696G>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 767074 | c.3705T>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 767077 | c.3708G>T | synonymous_variant | 0.16 | rifampicin | |
rpoC | 767087 | p.Cys1240Arg | missense_variant | 0.16 | rifampicin | |
rpoC | 767093 | c.3724_3725delAGinsTC | synonymous_variant | 0.16 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 767099 | p.Lys1244Gln | missense_variant | 0.15 | rifampicin | |
rpoC | 767106 | p.Asn1246Ile | missense_variant | 0.17 | rifampicin | |
rpoC | 767110 | c.3741T>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>T | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
Rv1129c | 1254582 | c.-48A>G | upstream_gene_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
isoniazid | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
fbiC | 1302899 | c.-32A>G | upstream_gene_variant | 1.0 | pretomanid | |
delamanid | Uncertain significance | |||||
clofazimine | Uncertain significance | |||||
sigE | 1364961 | c.549A>C | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
embR | 1417554 | c.-207C>G | upstream_gene_variant | 1.0 | ethambutol | |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471922 | n.78delT | non_coding_transcript_exon_variant | 0.52 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 0.53 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1471928 | n.83T>G | non_coding_transcript_exon_variant | 0.54 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471930 | n.85_89delGGAGAinsTTGCAGGG | non_coding_transcript_exon_variant | 0.54 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471978 | n.133C>T | non_coding_transcript_exon_variant | 0.51 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471979 | n.134T>C | non_coding_transcript_exon_variant | 0.52 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471981 | n.136C>T | non_coding_transcript_exon_variant | 0.52 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471996 | n.151C>T | non_coding_transcript_exon_variant | 0.51 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472106 | n.261G>A | non_coding_transcript_exon_variant | 0.61 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.62 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472123 | n.278A>T | non_coding_transcript_exon_variant | 0.72 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472150 | n.305T>G | non_coding_transcript_exon_variant | 0.79 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472151 | n.306C>A | non_coding_transcript_exon_variant | 0.79 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472160 | n.315C>T | non_coding_transcript_exon_variant | 0.78 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472285 | n.440A>G | non_coding_transcript_exon_variant | 0.46 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472287 | n.442C>T | non_coding_transcript_exon_variant | 0.42 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472289 | n.444T>G | non_coding_transcript_exon_variant | 0.42 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472290 | n.445C>G | non_coding_transcript_exon_variant | 0.42 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472298 | n.453delGinsCCA | non_coding_transcript_exon_variant | 0.43 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472307 | n.462_466delCTCTCinsTGGT | non_coding_transcript_exon_variant | 0.46 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472313 | n.469_470delAT | non_coding_transcript_exon_variant | 0.46 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472324 | n.479G>C | non_coding_transcript_exon_variant | 0.43 | kanamycin | |
capreomycin | ||||||
streptomycin | Uncertain significance | |||||
amikacin | ||||||
rrs | 1472325 | n.480G>C | non_coding_transcript_exon_variant | 0.43 | kanamycin | |
capreomycin | ||||||
streptomycin | Uncertain significance | |||||
amikacin | ||||||
rrs | 1472330 | n.485G>T | non_coding_transcript_exon_variant | 0.44 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472344 | n.499C>T | non_coding_transcript_exon_variant | 0.49 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472435 | n.590T>C | non_coding_transcript_exon_variant | 0.71 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472438 | n.593T>C | non_coding_transcript_exon_variant | 0.72 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472439 | n.594C>T | non_coding_transcript_exon_variant | 0.72 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472447 | n.602C>T | non_coding_transcript_exon_variant | 0.72 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472448 | n.603T>C | non_coding_transcript_exon_variant | 0.72 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472450 | n.605A>G | non_coding_transcript_exon_variant | 0.72 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472451 | n.606C>G | non_coding_transcript_exon_variant | 0.72 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472461 | n.616G>C | non_coding_transcript_exon_variant | 0.71 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472462 | n.617T>C | non_coding_transcript_exon_variant | 0.71 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 0.72 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472471 | n.626G>A | non_coding_transcript_exon_variant | 0.73 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472485 | n.640delGinsAT | non_coding_transcript_exon_variant | 0.78 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472489 | n.644A>T | non_coding_transcript_exon_variant | 0.78 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472494 | n.649A>G | non_coding_transcript_exon_variant | 0.78 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472498 | n.653C>T | non_coding_transcript_exon_variant | 0.78 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472530 | n.685G>A | non_coding_transcript_exon_variant | 0.8 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472557 | n.712G>A | non_coding_transcript_exon_variant | 0.75 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472558 | n.713G>A | non_coding_transcript_exon_variant | 0.75 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472569 | n.724G>A | non_coding_transcript_exon_variant | 0.73 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472607 | n.762G>A | non_coding_transcript_exon_variant | 0.81 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472612 | n.767G>T | non_coding_transcript_exon_variant | 0.81 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472660 | n.815T>C | non_coding_transcript_exon_variant | 0.76 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472661 | n.816A>G | non_coding_transcript_exon_variant | 0.76 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472670 | n.825_831delGGGTTTCinsAGGGGT | non_coding_transcript_exon_variant | 0.76 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472682 | n.837T>A | non_coding_transcript_exon_variant | 0.75 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472683 | n.838T>C | non_coding_transcript_exon_variant | 0.75 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472685 | n.840G>A | non_coding_transcript_exon_variant | 0.75 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472686 | n.841G>C | non_coding_transcript_exon_variant | 0.75 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472687 | n.842A>T | non_coding_transcript_exon_variant | 0.74 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472690 | n.845C>T | non_coding_transcript_exon_variant | 0.75 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | ||||||
rrs | 1472713 | n.868T>C | non_coding_transcript_exon_variant | 0.77 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472714 | n.869A>G | non_coding_transcript_exon_variant | 0.77 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472828 | n.983T>C | non_coding_transcript_exon_variant | 0.3 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472895 | n.1050C>T | non_coding_transcript_exon_variant | 0.56 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472957 | n.1112C>T | non_coding_transcript_exon_variant | 0.76 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472973 | n.1128A>T | non_coding_transcript_exon_variant | 0.75 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472987 | n.1142G>A | non_coding_transcript_exon_variant | 0.76 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473035 | n.1190G>A | non_coding_transcript_exon_variant | 0.7 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473080 | n.1235C>T | non_coding_transcript_exon_variant | 0.57 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473089 | n.1244A>C | non_coding_transcript_exon_variant | 0.49 | kanamycin | |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473091 | n.1246G>C | non_coding_transcript_exon_variant | 0.45 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473093 | n.1248C>T | non_coding_transcript_exon_variant | 0.45 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473097 | n.1252G>C | non_coding_transcript_exon_variant | 0.46 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473099 | n.1254T>G | non_coding_transcript_exon_variant | 0.46 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473100 | n.1255G>C | non_coding_transcript_exon_variant | 0.47 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.46 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.46 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473109 | n.1264T>G | non_coding_transcript_exon_variant | 0.46 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.47 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473112 | n.1267A>C | non_coding_transcript_exon_variant | 0.48 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473115 | n.1270G>T | non_coding_transcript_exon_variant | 0.49 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473120 | n.1275C>G | non_coding_transcript_exon_variant | 0.49 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473121 | n.1276T>C | non_coding_transcript_exon_variant | 0.49 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473123 | n.1278A>G | non_coding_transcript_exon_variant | 0.51 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473132 | n.1287T>C | non_coding_transcript_exon_variant | 0.58 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.69 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.73 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473259 | n.1414C>T | non_coding_transcript_exon_variant | 0.82 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473283 | n.1438T>C | non_coding_transcript_exon_variant | 0.76 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.74 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473292 | n.1447_1449delGGAinsTGGG | non_coding_transcript_exon_variant | 0.74 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrl | 1474130 | n.473C>T | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474135 | n.478G>A | non_coding_transcript_exon_variant | 0.51 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.54 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474182 | n.525C>A | non_coding_transcript_exon_variant | 0.56 | capreomycin | |
linezolid | ||||||
rrl | 1474183 | n.526T>G | non_coding_transcript_exon_variant | 0.57 | capreomycin | |
linezolid | ||||||
rrl | 1474184 | n.527C>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474185 | n.529delA | non_coding_transcript_exon_variant | 0.57 | capreomycin | |
linezolid | ||||||
rrl | 1474200 | n.545delT | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.78 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474263 | n.606G>A | non_coding_transcript_exon_variant | 0.78 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474269 | n.612C>T | non_coding_transcript_exon_variant | 0.77 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474286 | n.629_636delCTCCTTTTinsA | non_coding_transcript_exon_variant | 0.73 | capreomycin | |
linezolid | ||||||
rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 0.71 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474311 | n.654_655insT | non_coding_transcript_exon_variant | 0.72 | capreomycin | |
linezolid | ||||||
rrl | 1474351 | n.694G>C | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474353 | n.696A>G | non_coding_transcript_exon_variant | 0.69 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.66 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474384 | n.727C>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1474387 | n.730C>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474447 | n.790G>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1474451 | n.794T>C | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
rrl | 1474487 | n.830G>T | non_coding_transcript_exon_variant | 0.63 | capreomycin | |
linezolid | ||||||
rrl | 1474495 | n.838G>A | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
linezolid | ||||||
rrl | 1474496 | n.839C>G | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474497 | n.840G>A | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474506 | n.849C>T | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474507 | n.850G>T | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474508 | n.851C>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474517 | n.860C>G | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
linezolid | ||||||
rrl | 1474537 | n.880G>A | non_coding_transcript_exon_variant | 0.63 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474552 | n.895C>T | non_coding_transcript_exon_variant | 0.65 | capreomycin | |
linezolid | ||||||
rrl | 1474734 | n.1077G>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474736 | n.1079C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1474749 | n.1092C>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474751 | n.1094G>A | non_coding_transcript_exon_variant | 0.43 | capreomycin | |
linezolid | ||||||
rrl | 1474753 | n.1097delC | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.51 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474803 | n.1146G>A | non_coding_transcript_exon_variant | 0.71 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.72 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>G | non_coding_transcript_exon_variant | 0.72 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474824 | n.1167A>G | non_coding_transcript_exon_variant | 0.72 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474825 | n.1168G>A | non_coding_transcript_exon_variant | 0.72 | capreomycin | |
linezolid | ||||||
rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 0.73 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474837 | n.1180A>G | non_coding_transcript_exon_variant | 0.73 | capreomycin | |
linezolid | ||||||
rrl | 1474864 | n.1207C>T | non_coding_transcript_exon_variant | 0.74 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1474896 | n.1239A>G | non_coding_transcript_exon_variant | 0.69 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474901 | n.1244A>G | non_coding_transcript_exon_variant | 0.7 | capreomycin | |
linezolid | ||||||
rrl | 1474904 | n.1247G>C | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474913 | n.1256T>C | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474921 | n.1264C>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474932 | n.1275C>T | non_coding_transcript_exon_variant | 0.51 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475514 | n.1857G>A | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475531 | n.1874C>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475539 | n.1882A>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475542 | n.1885A>G | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475544 | n.1887A>T | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475545 | n.1888T>G | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475550 | n.1893A>G | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475672 | n.2015C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475694 | n.2037_2038insAAC | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1475697 | n.2040C>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475698 | n.2042delC | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1475703 | n.2046A>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475704 | n.2047C>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1475753 | n.2096C>T | non_coding_transcript_exon_variant | 0.71 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475758 | n.2101_2107delACCCGCAinsG | non_coding_transcript_exon_variant | 0.47 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2108A>G | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475769 | n.2112_2113insC | non_coding_transcript_exon_variant | 0.69 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.84 | capreomycin | |
linezolid | ||||||
rrl | 1475883 | n.2226A>T | non_coding_transcript_exon_variant | 0.84 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475884 | n.2227A>G | non_coding_transcript_exon_variant | 0.84 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475897 | n.2240T>C | non_coding_transcript_exon_variant | 0.84 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475900 | n.2243A>G | non_coding_transcript_exon_variant | 0.84 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475902 | n.2245T>C | non_coding_transcript_exon_variant | 0.84 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475906 | n.2249C>T | non_coding_transcript_exon_variant | 0.84 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475916 | n.2259C>G | non_coding_transcript_exon_variant | 0.83 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475975 | n.2318C>T | non_coding_transcript_exon_variant | 0.74 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 0.73 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.73 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1475997 | n.2340A>T | non_coding_transcript_exon_variant | 0.69 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476028 | n.2372_2375delAACC | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1476034 | n.2377_2378insATGT | non_coding_transcript_exon_variant | 0.43 | capreomycin | |
linezolid | ||||||
rrl | 1476040 | n.2383C>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1476046 | n.2389G>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1476048 | n.2391G>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>G | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1476050 | n.2393G>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
rrl | 1476080 | n.2423T>G | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.13 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476113 | n.2456T>G | non_coding_transcript_exon_variant | 0.13 | capreomycin | |
linezolid | ||||||
rrl | 1476116 | n.2459A>G | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476160 | n.2503T>C | non_coding_transcript_exon_variant | 0.65 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476194 | n.2537A>G | non_coding_transcript_exon_variant | 0.74 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476200 | n.2543A>T | non_coding_transcript_exon_variant | 0.73 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476201 | n.2544C>T | non_coding_transcript_exon_variant | 0.74 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476204 | n.2547C>T | non_coding_transcript_exon_variant | 0.74 | capreomycin | |
linezolid | ||||||
rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.77 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.81 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 0.83 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476250 | n.2593C>G | non_coding_transcript_exon_variant | 0.85 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476252 | n.2595T>G | non_coding_transcript_exon_variant | 0.84 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476257 | n.2600G>C | non_coding_transcript_exon_variant | 0.84 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.84 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.84 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476297 | n.2640C>T | non_coding_transcript_exon_variant | 0.82 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476298 | n.2641C>A | non_coding_transcript_exon_variant | 0.83 | capreomycin | |
linezolid | ||||||
rrl | 1476300 | n.2643G>T | non_coding_transcript_exon_variant | 0.82 | capreomycin | |
linezolid | ||||||
rrl | 1476301 | n.2644A>T | non_coding_transcript_exon_variant | 0.83 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476309 | n.2652G>T | non_coding_transcript_exon_variant | 0.84 | capreomycin | |
linezolid | ||||||
rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.84 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476523 | n.2867delC | non_coding_transcript_exon_variant | 0.84 | capreomycin | |
linezolid | ||||||
rrl | 1476534 | n.2877A>T | non_coding_transcript_exon_variant | 0.84 | capreomycin | |
linezolid | ||||||
rrl | 1476539 | n.2882A>G | non_coding_transcript_exon_variant | 0.83 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476540 | n.2883C>G | non_coding_transcript_exon_variant | 0.83 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476573 | n.2916A>T | non_coding_transcript_exon_variant | 0.72 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476580 | n.2923G>A | non_coding_transcript_exon_variant | 0.66 | capreomycin | |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.65 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476585 | n.2928A>G | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.63 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476607 | n.2950C>G | non_coding_transcript_exon_variant | 0.46 | capreomycin | |
linezolid | ||||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476614 | n.2957A>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1476616 | n.2959A>G | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476624 | n.2967T>A | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476629 | n.2972C>A | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476630 | n.2973A>G | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rpsA | 1833949 | c.408T>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1833955 | c.414G>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1833961 | c.420C>G | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1833970 | c.429G>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1833976 | c.435C>T | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1833994 | c.453G>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833997 | c.456G>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834009 | c.468C>T | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834012 | c.471G>T | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834015 | c.474G>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834025 | p.Gln162Asp | missense_variant | 0.29 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834040 | p.Lys167Gln | missense_variant | 0.3 | pyrazinamide | |
rpsA | 1834046 | p.Ile169Leu | missense_variant | 0.29 | pyrazinamide | |
rpsA | 1834076 | p.Asn179His | missense_variant | 0.32 | pyrazinamide | |
rpsA | 1834093 | c.552G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834105 | c.564C>T | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834108 | c.567C>A | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834114 | c.573G>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834468 | c.927A>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834474 | c.933C>G | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834483 | c.942G>A | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834501 | c.960G>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834504 | c.963G>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834522 | c.981C>T | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834523 | p.Glu328Gln | missense_variant | 0.19 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834534 | c.993C>G | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834540 | c.999G>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834543 | c.1002C>G | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834552 | c.1011G>T | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834555 | c.1014T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834556 | p.Ala339Thr | missense_variant | 0.18 | pyrazinamide | Uncertain significance |
rpsA | 1834567 | p.Asp342Glu | missense_variant | 0.23 | pyrazinamide | |
rpsA | 1834570 | p.Asp343Glu | missense_variant | 0.23 | pyrazinamide | |
rpsA | 1834573 | c.1032G>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834600 | c.1059G>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834606 | c.1065C>T | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1834859 | p.Ala440Thr | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
bacA | 2062922 | p.Ile603Val | missense_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
streptomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
bacA | 2062946 | p.Ser595Gly | missense_variant | 0.98 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
ndh | 2102106 | p.Gly313Arg | missense_variant | 1.0 | isoniazid | Not assoc w R - Interim |
delamanid | Uncertain significance | |||||
ethionamide | Uncertain significance | |||||
ndh | 2103173 | c.-132delG | upstream_gene_variant | 1.0 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Not assoc w R |
katG | 2155503 | c.609C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R |
katG | 2156025 | c.87C>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R |
katG | 2156465 | c.-354C>T | upstream_gene_variant | 1.0 | isoniazid | Not assoc w R - Interim |
PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
PPE35 | 2168011 | p.Ser868Arg | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
PPE35 | 2168814 | c.1798dupA | frameshift_variant | 1.0 | pyrazinamide | Uncertain significance |
Rv1979c | 2222308 | p.Asp286Gly | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
kasA | 2518132 | c.18C>T | synonymous_variant | 1.0 | isoniazid | |
Rv2477c | 2782927 | c.1116A>G | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2681 | 2997325 | p.Ala196Val | missense_variant | 1.0 | capreomycin | Uncertain significance |
Rv2752c | 3065888 | p.Val102Ile | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
thyX | 3067786 | p.Thr54Ala | missense_variant | 0.96 | para-aminosalicylic_acid | |
ald | 3086728 | c.-92C>T | upstream_gene_variant | 1.0 | cycloserine | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
ald | 3087084 | c.266delA | frameshift_variant | 1.0 | cycloserine | |
fbiD | 3339154 | p.Ile13Leu | missense_variant | 1.0 | pretomanid | |
delamanid | Uncertain significance | |||||
clofazimine | Uncertain significance | |||||
Rv3083 | 3448745 | p.Ile81Ser | missense_variant | 1.0 | ethionamide | Uncertain significance |
Rv3083 | 3448783 | p.Val94Ile | missense_variant | 1.0 | ethionamide | Uncertain significance |
lpqB | 3623730 | p.Ser394Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
lpqB | 3624350 | c.561G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3624486 | p.Asp142Gly | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
lpqB | 3624593 | c.318G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3624710 | c.201G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
rpoA | 3878630 | c.-124delC | upstream_gene_variant | 1.0 | rifampicin | Not assoc w R |
clpC1 | 4038403 | c.2302T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
glpK | 4138377 | p.Val460Ala | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
streptomycin | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R | |||||
embC | 4239487 | c.-376T>C | upstream_gene_variant | 1.0 | ethambutol | Uncertain significance |
embC | 4240671 | p.Thr270Ile | missense_variant | 1.0 | ethambutol | Not assoc w R |
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embC | 4242970 | c.3108C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4244220 | c.988C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embB | 4246551 | p.Asn13Ser | missense_variant | 1.0 | ethambutol | Not assoc w R |
embB | 4246864 | c.351C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embB | 4247173 | c.660G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embB | 4247646 | p.Glu378Ala | missense_variant | 1.0 | ethambutol | Not assoc w R |
aftB | 4267858 | p.Ile327Val | missense_variant | 1.0 | ethambutol | Not assoc w R |
ubiA | 4269351 | c.483C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
ubiA | 4269387 | p.Glu149Asp | missense_variant | 1.0 | ethambutol | Not assoc w R |
ubiA | 4269606 | c.228T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
gid | 4407588 | c.615A>G | synonymous_variant | 1.0 | streptomycin | Not assoc w R |
gid | 4407743 | p.Arg154Trp | missense_variant | 1.0 | streptomycin | Uncertain significance |