TB-Profiler result

Run: SRR1062871
Summary

Run ID: SRR1062871

Sample name:

Date: 02-04-2023 18:37:49

Number of reads: 705185

Percentage reads mapped: 19.29

Strain: lineage4.3.4.2.1

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 0.98
lineage4.3.4 Euro-American (LAM) LAM RD174 0.98
lineage4.3.4.2 Euro-American (LAM) LAM1;LAM4;LAM11 RD174 1.0
lineage4.3.4.2.1 Euro-American (LAM) LAM11 RD174 0.97
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761139 p.His445Asp missense_variant 0.94 rifampicin
rpsL 781822 p.Lys88Arg missense_variant 0.33 streptomycin
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.7 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.72 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.51 kanamycin, capreomycin, aminoglycosides, amikacin
katG 2155128 p.Trp328Cys missense_variant 0.13 isoniazid
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
ethA 4326694 c.440_779del frameshift_variant 1.0 ethionamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5054 c.-186G>C upstream_gene_variant 0.17
gyrB 5739 p.Thr167Met missense_variant 0.14
gyrB 6140 p.Val301Leu missense_variant 1.0
gyrA 6346 c.-956C>A upstream_gene_variant 0.18
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8543 c.1242C>T synonymous_variant 0.14
gyrA 8780 p.Asp493Glu missense_variant 0.33
gyrA 9035 c.1734G>A synonymous_variant 0.13
gyrA 9061 p.Ala587Val missense_variant 0.13
gyrA 9083 p.Gln594His missense_variant 0.14
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491308 p.Ala176Ser missense_variant 0.18
mshA 576035 p.Ala230Ser missense_variant 0.4
ccsA 620008 p.Arg40Ser missense_variant 0.2
ccsA 620151 c.261C>T synonymous_variant 0.5
ccsA 620414 p.His175Pro missense_variant 0.29
ccsA 620464 p.Ala192Ser missense_variant 0.29
rpoB 759934 p.Glu43Val missense_variant 0.22
rpoB 760562 p.Met252Ile missense_variant 0.29
rpoB 760703 c.897C>A synonymous_variant 0.14
rpoB 761354 c.1548C>A synonymous_variant 0.17
rpoB 761555 c.1749G>C synonymous_variant 0.29
rpoB 761559 p.Thr585Ser missense_variant 0.29
rpoB 761565 p.Met587Leu missense_variant 0.31
rpoB 761570 c.1764T>C synonymous_variant 0.29
rpoB 761573 c.1767C>G synonymous_variant 0.26
rpoB 761579 c.1773G>C synonymous_variant 0.25
rpoB 761600 c.1794T>C synonymous_variant 0.28
rpoB 761612 c.1806G>T synonymous_variant 0.29
rpoB 761615 c.1809A>G synonymous_variant 0.28
rpoB 761627 c.1821C>T synonymous_variant 0.22
rpoB 761633 c.1827G>C synonymous_variant 0.21
rpoB 761961 p.Pro719Ser missense_variant 0.24
rpoB 761973 p.His723Tyr missense_variant 0.2
rpoB 761980 p.Tyr725Phe missense_variant 0.23
rpoB 761987 c.2181C>T synonymous_variant 0.24
rpoB 761999 c.2193G>C synonymous_variant 0.23
rpoB 762002 c.2196C>G synonymous_variant 0.25
rpoB 762003 p.Asn733Gln missense_variant 0.26
rpoB 762015 p.Glu737Gln missense_variant 0.33
rpoB 762020 p.Glu738Asp missense_variant 0.35
rpoB 762026 c.2220G>C synonymous_variant 0.35
rpoB 762030 p.Thr742Ser missense_variant 0.38
rpoB 762053 c.2247T>C synonymous_variant 0.41
rpoB 762057 p.Ile751Val missense_variant 0.4
rpoB 762062 c.2256T>C synonymous_variant 0.31
rpoB 762065 c.2259T>C synonymous_variant 0.33
rpoB 762080 c.2274G>C synonymous_variant 0.31
rpoB 762086 c.2280G>C synonymous_variant 0.27
rpoB 762101 c.2295C>G synonymous_variant 0.2
rpoB 762185 c.2379G>C synonymous_variant 0.23
rpoB 762194 c.2388G>C synonymous_variant 0.33
rpoB 762233 c.2427G>C synonymous_variant 0.41
rpoB 762245 c.2439G>T synonymous_variant 0.33
rpoB 762251 c.2445G>C synonymous_variant 0.33
rpoB 762254 c.2448T>G synonymous_variant 0.33
rpoB 762257 c.2451C>G synonymous_variant 0.32
rpoB 762273 p.Ala823Ser missense_variant 0.33
rpoB 762278 c.2472C>T synonymous_variant 0.3
rpoB 762284 c.2478G>C synonymous_variant 0.3
rpoB 762293 c.2487T>C synonymous_variant 0.13
rpoC 762866 c.-504C>A upstream_gene_variant 0.18
rpoB 762878 p.Ile1024Met missense_variant 0.24
rpoB 762879 p.Met1025Leu missense_variant 0.24
rpoC 762887 c.-483G>C upstream_gene_variant 0.38
rpoC 762896 c.-474G>C upstream_gene_variant 0.23
rpoC 762899 c.-471G>C upstream_gene_variant 0.58
rpoC 762917 c.-453C>G upstream_gene_variant 0.63
rpoC 762920 c.-450C>T upstream_gene_variant 0.3
rpoC 762923 c.-447C>G upstream_gene_variant 0.61
rpoB 762925 p.Thr1040Ile missense_variant 0.3
rpoC 762929 c.-441G>T upstream_gene_variant 0.31
rpoB 762934 c.3129_3130insAGCC frameshift_variant 0.3
rpoB 762938 c.3133_3136delATGA frameshift_variant 0.35
rpoC 762980 c.-390T>C upstream_gene_variant 0.42
rpoC 762983 c.-387C>T upstream_gene_variant 0.45
rpoC 762989 c.-381G>C upstream_gene_variant 0.68
rpoC 762995 c.-375G>T upstream_gene_variant 0.58
rpoB 763002 c.3197dupA frameshift_variant 0.33
rpoB 763006 c.3201delC frameshift_variant 0.25
rpoB 763014 p.Met1070Leu missense_variant 0.23
rpoB 763017 p.Gln1071Glu missense_variant 0.23
rpoC 763031 c.-339T>G upstream_gene_variant 0.25
rpoC 763034 c.-336C>G upstream_gene_variant 0.23
rpoC 763040 c.-330C>G upstream_gene_variant 0.25
rpoC 763085 c.-285C>T upstream_gene_variant 0.14
rpoC 763094 c.-276G>C upstream_gene_variant 0.27
rpoC 763100 c.-270G>A upstream_gene_variant 0.4
rpoC 763103 c.-267G>C upstream_gene_variant 0.4
rpoB 763122 p.Ile1106Leu missense_variant 0.36
rpoC 763127 c.-243G>C upstream_gene_variant 0.36
rpoB 763130 p.Glu1108Asp missense_variant 0.36
rpoC 763136 c.-234C>A upstream_gene_variant 0.36
rpoC 763157 c.-213G>C upstream_gene_variant 0.18
rpoC 763160 c.-210G>C upstream_gene_variant 0.17
rpoB 763161 p.Leu1119Ile missense_variant 0.17
rpoC 763166 c.-204A>G upstream_gene_variant 0.15
rpoC 763169 c.-201A>G upstream_gene_variant 0.14
rpoB 763170 p.Leu1122Met missense_variant 0.14
rpoC 763456 c.87A>G synonymous_variant 0.22
rpoC 763468 c.99G>C synonymous_variant 0.27
rpoC 763483 c.114G>C synonymous_variant 0.42
rpoC 763486 c.117T>G synonymous_variant 0.43
rpoC 763504 c.135C>A synonymous_variant 0.56
rpoC 763507 c.138G>C synonymous_variant 0.57
rpoC 763528 c.159G>C synonymous_variant 0.55
rpoC 763531 c.162G>C synonymous_variant 0.54
rpoC 763534 c.165T>C synonymous_variant 0.53
rpoC 763537 c.168C>T synonymous_variant 0.51
rpoC 763546 c.177A>G synonymous_variant 0.5
rpoC 763550 p.Tyr61Ala missense_variant 0.5
rpoC 763570 c.201G>C synonymous_variant 0.57
rpoC 763585 c.216C>G synonymous_variant 0.61
rpoC 763621 c.252C>T synonymous_variant 0.57
rpoC 763633 c.264T>C synonymous_variant 0.59
rpoC 763642 c.273G>C synonymous_variant 0.59
rpoC 763660 c.291T>C synonymous_variant 0.57
rpoC 763666 c.297G>T synonymous_variant 0.59
rpoC 763696 c.327T>C synonymous_variant 0.6
rpoC 763699 c.330G>T synonymous_variant 0.64
rpoC 763708 c.339G>C synonymous_variant 0.62
rpoC 763709 c.340C>T synonymous_variant 0.62
rpoC 763714 c.345G>C synonymous_variant 0.56
rpoC 763717 c.348T>C synonymous_variant 0.56
rpoC 763723 c.354G>C synonymous_variant 0.56
rpoC 763726 c.357C>T synonymous_variant 0.56
rpoC 763729 c.360G>C synonymous_variant 0.56
rpoC 763732 c.363C>G synonymous_variant 0.56
rpoC 763744 c.375G>C synonymous_variant 0.42
rpoC 763751 p.Ile128Val missense_variant 0.33
rpoC 763765 c.396T>C synonymous_variant 0.17
rpoC 764333 p.Pro322Thr missense_variant 0.29
rpoC 764458 c.1089G>C synonymous_variant 0.18
rpoC 764461 c.1092A>G synonymous_variant 0.2
rpoC 764491 c.1122G>C synonymous_variant 0.25
rpoC 764498 p.Ser377Ala missense_variant 0.25
rpoC 764503 c.1134G>C synonymous_variant 0.25
rpoC 764507 p.Ala380Ser missense_variant 0.33
rpoC 764521 c.1152T>C synonymous_variant 0.44
rpoC 764524 c.1155C>T synonymous_variant 0.44
rpoC 764527 c.1158C>T synonymous_variant 0.43
rpoC 764533 c.1164C>T synonymous_variant 0.39
rpoC 764536 c.1167G>T synonymous_variant 0.4
rpoC 764542 c.1173C>G synonymous_variant 0.43
rpoC 764548 c.1179G>A synonymous_variant 0.45
rpoC 764560 c.1191T>C synonymous_variant 0.4
rpoC 764575 c.1206T>G synonymous_variant 0.48
rpoC 764578 c.1209C>G synonymous_variant 0.32
rpoC 764581 c.1212T>C synonymous_variant 0.49
rpoC 764582 p.Leu405Met missense_variant 0.5
rpoC 764587 c.1218C>G synonymous_variant 0.21
rpoC 764593 c.1224C>T synonymous_variant 0.24
rpoC 764605 c.1236G>C synonymous_variant 0.39
rpoC 764611 c.1242G>T synonymous_variant 0.59
rpoC 764632 c.1263T>C synonymous_variant 0.75
rpoC 764641 c.1272C>T synonymous_variant 0.57
rpoC 764650 c.1281G>T synonymous_variant 0.81
rpoC 764662 c.1293G>C synonymous_variant 0.26
rpoC 764663 p.Val432Thr missense_variant 0.52
rpoC 764668 c.1299C>T synonymous_variant 0.27
rpoC 764672 p.Gln435Glu missense_variant 0.52
rpoC 764677 c.1308C>G synonymous_variant 0.48
rpoC 764679 p.Lys437Ser missense_variant 0.26
rpoC 764683 c.1314G>C synonymous_variant 0.2
rpoC 764690 p.Cys441Ala missense_variant 0.24
rpoC 764695 c.1326T>C synonymous_variant 0.44
rpoC 764701 c.1332C>G synonymous_variant 0.62
rpoC 764705 p.Leu446Thr missense_variant 0.56
rpoC 764716 c.1347G>C synonymous_variant 0.61
rpoC 764737 c.1368G>C synonymous_variant 0.56
rpoC 764746 c.1377G>C synonymous_variant 0.41
rpoC 764752 c.1383G>C synonymous_variant 0.36
rpoC 764755 c.1386C>T synonymous_variant 0.38
rpoC 764764 c.1395T>C synonymous_variant 0.42
rpoC 764780 c.1411_1413delAGCinsTCG synonymous_variant 0.33
rpoC 764797 c.1428G>C synonymous_variant 0.43
rpoC 764803 c.1434C>T synonymous_variant 0.31
rpoC 764808 p.Arg480His missense_variant 0.33
rpoC 764812 c.1443C>G synonymous_variant 0.2
rpoC 764815 c.1446A>G synonymous_variant 0.22
rpoC 764935 c.1566T>C synonymous_variant 0.12
rpoC 764948 c.1579_1581delTTGinsCTC synonymous_variant 0.18
rpoC 764956 c.1587T>C synonymous_variant 0.17
rpoC 764957 p.Glu530Ser missense_variant 0.18
rpoC 764968 c.1599T>C synonymous_variant 0.15
rpoC 764995 c.1626C>G synonymous_variant 0.82
rpoC 764998 c.1629G>C synonymous_variant 0.19
rpoC 765007 c.1638T>G synonymous_variant 0.16
rpoC 765008 c.1639T>C synonymous_variant 0.17
rpoC 765014 p.Ala549Pro missense_variant 0.17
rpoC 765019 c.1650A>G synonymous_variant 0.18
rpoC 765150 p.Gly594Ala missense_variant 0.14
rpoC 765958 c.2589C>G synonymous_variant 0.13
rpoC 765962 c.2593T>C synonymous_variant 0.13
rpoC 766446 p.Gly1026Val missense_variant 0.22
rpoC 767064 p.Val1232Ala missense_variant 0.67
rpoC 767083 c.3714C>T synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775712 c.2769G>T synonymous_variant 0.18
mmpL5 776257 p.Ala742Thr missense_variant 0.13
mmpL5 776806 p.Gly559Arg missense_variant 0.13
mmpR5 778007 c.-983G>C upstream_gene_variant 0.13
mmpL5 779124 c.-644C>A upstream_gene_variant 0.25
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781417 c.-143G>T upstream_gene_variant 0.18
rpsL 781760 c.201T>C synonymous_variant 0.15
rpsL 781766 c.207C>T synonymous_variant 0.17
rpsL 781772 c.213C>A synonymous_variant 0.2
rpsL 781796 p.Met79Ile missense_variant 0.33
rpsL 781802 c.243G>C synonymous_variant 0.33
rpsL 781811 c.252C>T synonymous_variant 0.29
rpsL 781817 c.258G>T synonymous_variant 0.29
rpsL 781820 c.261G>C synonymous_variant 0.31
rpsL 781829 c.270G>T synonymous_variant 0.36
rpsL 781832 c.273T>G synonymous_variant 0.33
rpsL 781845 p.Lys96Arg missense_variant 0.29
rpsL 781851 p.Ile98Val missense_variant 0.21
rpsL 781865 c.306G>C synonymous_variant 0.25
rpsL 781868 c.309T>C synonymous_variant 0.2
rpsL 781871 c.312G>C synonymous_variant 0.2
rplC 801080 p.Ala91Asp missense_variant 0.22
fbiC 1302959 c.31_32delGC frameshift_variant 0.2
fbiC 1304388 c.1458C>T synonymous_variant 0.25
fbiC 1305284 p.Gln785Arg missense_variant 0.18
Rv1258c 1406864 c.477C>T synonymous_variant 0.2
Rv1258c 1407279 p.Ala21Glu missense_variant 0.22
Rv1258c 1407534 c.-194C>T upstream_gene_variant 0.14
embR 1416725 p.Trp208* stop_gained 0.25
embR 1417240 c.108G>A synonymous_variant 0.22
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.27
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.39
rrs 1472092 n.247C>T non_coding_transcript_exon_variant 0.53
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.56
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.58
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.58
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.53
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.54
rrs 1472120 n.275G>A non_coding_transcript_exon_variant 0.67
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.76
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.75
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.82
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.21
rrs 1472223 n.378C>G non_coding_transcript_exon_variant 0.49
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.74
rrs 1472228 n.383G>C non_coding_transcript_exon_variant 0.48
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.24
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.25
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 0.24
rrs 1472245 n.400C>A non_coding_transcript_exon_variant 0.42
rrs 1472251 n.406G>C non_coding_transcript_exon_variant 0.52
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.17
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.16
rrs 1472264 n.419T>C non_coding_transcript_exon_variant 0.15
rrs 1472266 n.421C>A non_coding_transcript_exon_variant 0.16
rrs 1472279 n.434T>G non_coding_transcript_exon_variant 0.22
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.12
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.14
rrs 1472337 n.492C>T non_coding_transcript_exon_variant 0.23
rrs 1472338 n.493A>C non_coding_transcript_exon_variant 0.14
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.42
rrs 1472349 n.504A>C non_coding_transcript_exon_variant 0.16
rrs 1472374 n.529T>G non_coding_transcript_exon_variant 0.2
rrs 1472379 n.534T>G non_coding_transcript_exon_variant 0.19
rrs 1472380 n.535G>A non_coding_transcript_exon_variant 0.29
rrs 1472382 n.537G>T non_coding_transcript_exon_variant 0.19
rrs 1472391 n.546C>T non_coding_transcript_exon_variant 0.17
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.25
rrs 1472412 n.567A>C non_coding_transcript_exon_variant 0.16
rrs 1472415 n.570T>A non_coding_transcript_exon_variant 0.14
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.12
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 0.21
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.12
rrs 1472484 n.639A>T non_coding_transcript_exon_variant 0.52
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.58
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.56
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.56
rrs 1472506 n.661A>T non_coding_transcript_exon_variant 0.69
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.69
rrs 1472572 n.727T>A non_coding_transcript_exon_variant 0.81
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.8
rrs 1472591 n.746G>A non_coding_transcript_exon_variant 0.79
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.78
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.63
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.56
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.38
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.66
rrs 1472715 n.870C>A non_coding_transcript_exon_variant 0.19
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.2
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.52
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.29
rrs 1472753 n.908A>C non_coding_transcript_exon_variant 0.23
rrs 1472770 n.925C>T non_coding_transcript_exon_variant 0.28
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.28
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.43
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.29
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.26
rrs 1472812 n.967A>C non_coding_transcript_exon_variant 0.25
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.38
rrs 1472826 n.981G>C non_coding_transcript_exon_variant 0.27
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.12
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.14
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.35
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.68
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.68
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.7
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.72
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.77
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.77
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.74
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.74
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.75
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.76
rrs 1473047 n.1202C>T non_coding_transcript_exon_variant 0.69
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.62
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.63
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.62
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.48
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.12
rrs 1473111 n.1266A>C non_coding_transcript_exon_variant 0.15
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.49
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.49
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.6
rrs 1473147 n.1302G>T non_coding_transcript_exon_variant 0.75
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.76
rrs 1473157 n.1312C>T non_coding_transcript_exon_variant 0.81
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.78
rrs 1473164 n.1319C>A non_coding_transcript_exon_variant 0.78
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.72
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.61
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.47
rrs 1473298 n.1453A>G non_coding_transcript_exon_variant 0.51
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.49
rrs 1473305 n.1460G>T non_coding_transcript_exon_variant 0.47
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.49
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.49
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.49
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.13
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.13
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.19
rrl 1473789 n.133dupC non_coding_transcript_exon_variant 0.12
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.36
rrl 1473833 n.176_177insT non_coding_transcript_exon_variant 0.39
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.3
rrl 1473884 n.227C>T non_coding_transcript_exon_variant 0.33
rrl 1473887 n.230T>G non_coding_transcript_exon_variant 0.33
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.33
rrl 1473889 n.232G>A non_coding_transcript_exon_variant 0.33
rrl 1473898 n.241C>G non_coding_transcript_exon_variant 0.33
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.33
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.26
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 0.35
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.53
rrl 1474171 n.514C>G non_coding_transcript_exon_variant 0.54
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.52
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.53
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.54
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 0.6
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.6
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.6
rrl 1474287 n.630T>A non_coding_transcript_exon_variant 0.49
rrl 1474290 n.633T>A non_coding_transcript_exon_variant 0.15
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.38
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.35
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.35
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.35
rrl 1474355 n.698A>G non_coding_transcript_exon_variant 0.37
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.36
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.34
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.35
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.33
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.34
rrl 1474406 n.749T>C non_coding_transcript_exon_variant 0.33
rrl 1474520 n.863A>C non_coding_transcript_exon_variant 0.28
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.28
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.28
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.29
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.3
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.35
rrl 1474551 n.894G>C non_coding_transcript_exon_variant 0.53
rrl 1474558 n.901G>T non_coding_transcript_exon_variant 0.64
rrl 1474584 n.927C>T non_coding_transcript_exon_variant 0.78
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.85
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.85
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.85
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.85
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.76
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.68
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.65
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.64
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 0.52
rrl 1474694 n.1037C>T non_coding_transcript_exon_variant 0.5
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 0.26
rrl 1474717 n.1060_1061insGGTTC non_coding_transcript_exon_variant 0.26
rrl 1474734 n.1077G>A non_coding_transcript_exon_variant 0.33
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.33
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.17
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.17
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.23
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.26
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.25
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.26
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.25
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.27
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.53
rrl 1474806 n.1149A>G non_coding_transcript_exon_variant 0.64
rrl 1474822 n.1165G>T non_coding_transcript_exon_variant 0.69
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.73
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.73
rrl 1474905 n.1248T>A non_coding_transcript_exon_variant 0.66
rrl 1474927 n.1271delC non_coding_transcript_exon_variant 0.29
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.28
rrl 1474975 n.1318G>A non_coding_transcript_exon_variant 0.12
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.27
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.5
rrl 1475109 n.1452C>T non_coding_transcript_exon_variant 0.46
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.46
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.46
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.48
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.5
rrl 1475175 n.1518G>C non_coding_transcript_exon_variant 0.46
rrl 1475176 n.1519G>A non_coding_transcript_exon_variant 0.46
rrl 1475187 n.1530C>T non_coding_transcript_exon_variant 0.26
rrl 1475188 n.1531C>G non_coding_transcript_exon_variant 0.19
rrl 1475488 n.1831G>T non_coding_transcript_exon_variant 0.18
rrl 1475499 n.1842C>T non_coding_transcript_exon_variant 0.36
rrl 1475500 n.1843_1844insT non_coding_transcript_exon_variant 0.36
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.56
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.59
rrl 1475536 n.1879C>T non_coding_transcript_exon_variant 0.59
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.56
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.56
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.54
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.54
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.54
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.57
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.2
rrl 1475655 n.1998T>A non_coding_transcript_exon_variant 0.19
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.31
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.42
rrl 1475696 n.2039T>A non_coding_transcript_exon_variant 0.58
rrl 1475697 n.2040C>T non_coding_transcript_exon_variant 0.58
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.58
rrl 1475703 n.2046A>T non_coding_transcript_exon_variant 0.59
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.7
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 0.22
rrl 1475765 n.2108A>T non_coding_transcript_exon_variant 0.22
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.77
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.72
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.7
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.7
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.7
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.7
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.67
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.6
rrl 1475963 n.2306G>A non_coding_transcript_exon_variant 0.55
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.37
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.35
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 0.35
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.34
rrl 1475989 n.2332T>G non_coding_transcript_exon_variant 0.33
rrl 1475990 n.2333G>C non_coding_transcript_exon_variant 0.34
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.38
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.38
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.17
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.34
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 0.45
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.45
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.62
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.65
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.67
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.61
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.61
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.55
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.49
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.27
rrl 1476336 n.2679C>G non_coding_transcript_exon_variant 0.41
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.35
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.41
rrl 1476357 n.2700T>A non_coding_transcript_exon_variant 0.41
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.41
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.4
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 0.4
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.4
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.47
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.41
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.44
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.45
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.48
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.43
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.42
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.43
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.42
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.4
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.82
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.37
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.34
rrl 1476491 n.2834T>C non_coding_transcript_exon_variant 0.25
rrl 1476501 n.2844C>T non_coding_transcript_exon_variant 0.19
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.75
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.62
rrl 1476519 n.2862C>T non_coding_transcript_exon_variant 0.63
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.57
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.6
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.6
rrl 1476534 n.2877A>T non_coding_transcript_exon_variant 0.61
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.63
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.63
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.62
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.64
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.76
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.76
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 0.68
rrl 1476603 n.2946G>T non_coding_transcript_exon_variant 0.67
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.64
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.68
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.69
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.68
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.68
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.67
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.68
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.47
rrl 1476665 n.3008T>G non_coding_transcript_exon_variant 0.36
rrl 1476670 n.3013A>G non_coding_transcript_exon_variant 0.19
fabG1 1673231 c.-209G>T upstream_gene_variant 0.12
fabG1 1673246 c.-194G>T upstream_gene_variant 0.12
fabG1 1673741 p.Thr101Ser missense_variant 0.17
inhA 1674491 p.Phe97Tyr missense_variant 0.25
rpsA 1833487 c.-55C>G upstream_gene_variant 0.4
rpsA 1833668 p.Ile43Val missense_variant 0.31
rpsA 1833676 c.135A>G synonymous_variant 0.29
rpsA 1833679 c.138G>C synonymous_variant 0.33
rpsA 1833682 c.141C>T synonymous_variant 0.33
rpsA 1833685 c.144G>C synonymous_variant 0.33
rpsA 1833694 c.153G>C synonymous_variant 0.33
rpsA 1833698 p.Leu53Val missense_variant 0.31
rpsA 1833709 c.168C>A synonymous_variant 0.29
rpsA 1833718 c.177C>G synonymous_variant 0.29
rpsA 1834189 c.648G>C synonymous_variant 0.2
rpsA 1834210 c.669C>T synonymous_variant 0.23
rpsA 1834213 c.672G>C synonymous_variant 0.23
rpsA 1834222 c.681T>C synonymous_variant 0.17
rpsA 1834228 c.687C>T synonymous_variant 0.15
rpsA 1834387 c.846C>T synonymous_variant 0.18
rpsA 1834395 p.Arg285Gln missense_variant 0.25
rpsA 1834408 c.867C>G synonymous_variant 0.31
rpsA 1834411 c.870T>C synonymous_variant 0.33
rpsA 1834416 p.Ala292Val missense_variant 0.36
rpsA 1834423 c.882G>C synonymous_variant 0.47
rpsA 1834451 c.910_912delTTGinsCTC synonymous_variant 0.48
rpsA 1834468 c.927A>G synonymous_variant 0.5
rpsA 1834474 c.933C>G synonymous_variant 0.52
rpsA 1834486 p.Glu315Asp missense_variant 0.48
rpsA 1834489 c.948T>C synonymous_variant 0.47
rpsA 1834501 c.960G>C synonymous_variant 0.42
rpsA 1834504 c.963G>C synonymous_variant 0.39
rpsA 1834519 c.978G>C synonymous_variant 0.33
rpsA 1834524 p.Glu328Val missense_variant 0.13
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918637 p.Pro233Gln missense_variant 0.14
ndh 2101740 p.Gln435* stop_gained 0.13
ndh 2102028 p.Gly339Arg missense_variant 0.12
ndh 2102294 p.Thr250Ile missense_variant 0.17
katG 2153948 p.Gln722Glu missense_variant 0.17
katG 2155605 c.507C>A synonymous_variant 0.13
katG 2156146 c.-35A>T upstream_gene_variant 0.18
PPE35 2170342 p.Gln91Lys missense_variant 0.22
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289003 p.Asp80Gly missense_variant 0.13
pncA 2290095 c.-854C>A upstream_gene_variant 0.2
eis 2714700 c.633C>T synonymous_variant 0.22
folC 2746192 c.1407C>A synonymous_variant 0.2
folC 2746213 c.1386G>A synonymous_variant 0.18
folC 2746561 c.1038C>G synonymous_variant 0.13
folC 2746903 c.696G>A synonymous_variant 0.15
pepQ 2860148 p.Gly91Ser missense_variant 0.22
pepQ 2860466 c.-48C>T upstream_gene_variant 0.13
ribD 2987422 p.Gly195Glu missense_variant 0.14
ribD 2987487 p.Pro217Ala missense_variant 0.25
Rv2752c 3066124 p.Gly23Ala missense_variant 0.17
thyX 3067676 c.270C>A synonymous_variant 0.29
thyA 3073766 p.Asp236Asn missense_variant 0.13
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3086929 p.Ala37Glu missense_variant 0.17
fbiD 3339018 c.-100G>C upstream_gene_variant 0.22
fbiD 3339033 c.-85G>T upstream_gene_variant 0.18
fbiD 3339318 c.201C>A synonymous_variant 0.4
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474427 p.Val141Leu missense_variant 0.13
fprA 3474833 p.Ile276Thr missense_variant 0.29
fprA 3475339 p.Ala445Ser missense_variant 0.25
whiB7 3568655 p.Gln9Lys missense_variant 0.2
Rv3236c 3612009 p.Ala370Thr missense_variant 1.0
Rv3236c 3612448 c.669G>A synonymous_variant 0.25
Rv3236c 3612652 c.465G>A synonymous_variant 0.22
Rv3236c 3612807 p.Gly104Ser missense_variant 0.2
fbiA 3640594 p.Gly18Arg missense_variant 0.18
alr 3840719 c.702A>G synonymous_variant 1.0
alr 3840869 c.552C>G synonymous_variant 1.0
rpoA 3878188 c.319delG frameshift_variant 0.22
ddn 3987197 p.Glu118Asp missense_variant 0.14
clpC1 4038287 c.2418C>T synonymous_variant 1.0
clpC1 4038443 c.2262G>T synonymous_variant 0.2
clpC1 4039588 p.Ser373Thr missense_variant 0.33
clpC1 4039593 p.Arg371Lys missense_variant 0.29
clpC1 4039611 p.Arg365Lys missense_variant 0.2
clpC1 4039616 c.1089G>C synonymous_variant 0.2
clpC1 4039661 c.1044T>C synonymous_variant 0.14
clpC1 4039664 c.1041G>C synonymous_variant 0.13
clpC1 4039667 p.Gln346Phe missense_variant 0.13
clpC1 4039673 c.1032G>T synonymous_variant 0.15
clpC1 4039682 c.1023C>G synonymous_variant 0.12
clpC1 4039697 c.1008C>G synonymous_variant 0.12
clpC1 4039714 p.Tyr331His missense_variant 0.14
clpC1 4039724 c.981A>G synonymous_variant 0.17
clpC1 4039733 c.972G>C synonymous_variant 0.17
clpC1 4039736 c.969C>G synonymous_variant 0.17
clpC1 4039739 c.966C>G synonymous_variant 0.26
clpC1 4039742 c.963C>T synonymous_variant 0.17
clpC1 4039751 c.954A>G synonymous_variant 0.17
clpC1 4039754 c.951G>C synonymous_variant 0.17
clpC1 4039757 c.948A>G synonymous_variant 0.18
clpC1 4039766 c.939T>C synonymous_variant 0.19
clpC1 4039773 p.Lys311Met missense_variant 0.18
clpC1 4039778 c.927A>G synonymous_variant 0.18
clpC1 4039781 c.924G>C synonymous_variant 0.18
clpC1 4039790 c.915C>A synonymous_variant 0.16
clpC1 4039802 c.903G>C synonymous_variant 0.13
clpC1 4039976 p.Lys243Thr missense_variant 0.38
clpC1 4039982 p.Thr241Ile missense_variant 0.35
clpC1 4039991 c.714G>T synonymous_variant 0.35
clpC1 4040002 p.His235Asn missense_variant 0.3
clpC1 4040003 c.702G>C synonymous_variant 0.3
clpC1 4040009 c.696C>G synonymous_variant 0.36
clpC1 4040021 c.684A>T synonymous_variant 0.48
clpC1 4040024 c.681A>G synonymous_variant 0.45
clpC1 4040030 c.675C>G synonymous_variant 0.45
clpC1 4040033 c.672G>C synonymous_variant 0.46
clpC1 4040063 c.642G>C synonymous_variant 0.36
clpC1 4040066 c.639G>T synonymous_variant 0.36
clpC1 4040081 c.624C>G synonymous_variant 0.29
clpC1 4040087 c.618G>C synonymous_variant 0.27
clpC1 4040090 c.615T>C synonymous_variant 0.27
clpC1 4040096 p.Val203Ile missense_variant 0.15
clpC1 4040274 p.Gly144Val missense_variant 0.29
panD 4044047 p.Val79Leu missense_variant 0.17
embC 4240895 p.Arg345Gly missense_variant 0.18
embC 4241456 p.Ala532Pro missense_variant 0.22
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4243033 p.Trp1057Cys missense_variant 0.33
embA 4243424 c.192C>T synonymous_variant 0.18
embA 4243482 c.252delC frameshift_variant 0.13
embA 4244523 p.Pro431Ser missense_variant 0.17
embA 4245205 p.Gly658Glu missense_variant 0.15
embA 4245454 p.Ala741Asp missense_variant 0.12
embB 4246686 p.Trp58Leu missense_variant 0.25
embB 4247455 c.942C>A synonymous_variant 0.12
embB 4247971 c.1458C>A synonymous_variant 0.2
embB 4248184 p.Met557Ile missense_variant 0.22
embB 4248519 p.Ser669Ile missense_variant 0.18
embB 4249312 c.2799C>A synonymous_variant 0.15
embB 4249472 p.Asp987Tyr missense_variant 0.17
embB 4249662 p.Ala1050Val missense_variant 0.2
ethA 4327436 p.Gly13Val missense_variant 0.14
ethA 4327536 c.-63C>G upstream_gene_variant 0.17
ethR 4327610 p.Ser21Cys missense_variant 0.33
whiB6 4338288 c.234G>T synonymous_variant 0.15
whiB6 4338459 p.Met21Ile missense_variant 0.14
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407604 p.Ala200Val missense_variant 0.15
gid 4407775 p.Asp143Val missense_variant 0.17
gid 4408156 p.Leu16Arg missense_variant 1.0
gid 4408212 c.-10G>A upstream_gene_variant 0.15