TB-Profiler result

Run: SRR1175496
Summary

Run ID: SRR1175496

Sample name:

Date: 2024-03-26T16:46:22.834181

Number of reads: 97634

Percentage reads mapped: 9.59

Median coverage: 1.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 0.96
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 705 c.705A>G synonymous_variant 0.91 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.91 isoniazid
dnaA 714 c.714C>T synonymous_variant 0.91 isoniazid
dnaA 720 c.720G>A synonymous_variant 0.91 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 747 c.747G>T synonymous_variant 0.92 isoniazid
dnaA 748 c.748_750delCTCinsTG frameshift_variant&missense_variant 0.92 isoniazid Uncertain significance
dnaA 763 p.Lys255Arg missense_variant 0.92 isoniazid
dnaA 771 c.771A>G synonymous_variant 0.93 isoniazid
dnaA 793 c.793_795delGTAinsAC frameshift_variant&missense_variant 0.92 isoniazid Uncertain significance
dnaA 801 c.801G>T synonymous_variant 0.9 isoniazid
dnaA 804 c.804G>C synonymous_variant 0.8 isoniazid
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.8 isoniazid Uncertain significance
dnaA 822 c.822A>G synonymous_variant 0.86 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.81 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 0.67 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.67 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.67 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.67 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.73 isoniazid Not assoc w R - Interim
gyrB 6151 c.912C>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrB 6172 c.933C>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrB 6184 c.945C>T synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6193 c.954G>A synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 6728 c.1489_1491delCTAinsTG frameshift_variant&stop_gained 0.92 levofloxacin Uncertain significance
moxifloxacin
gyrA 6739 c.-563C>T upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8870 c.1569G>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8942 c.1641G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8946 c.1645T>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8957 c.1656C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Lys missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8978 c.1677C>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
nusG 734445 c.192C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734452 c.199_201delGAAinsCG frameshift_variant&missense_variant 0.92 rifampicin
nusG 734460 c.207G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734497 c.244_246delGTGinsAC frameshift_variant&missense_variant 0.94 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734535 c.282C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734538 c.285C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.8 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760388 c.582C>T synonymous_variant 0.9 rifampicin
rpoB 760400 c.594G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 0.9 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 760418 c.612G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760668 c.862_864delACGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760703 c.897C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760721 c.915C>G synonymous_variant 0.91 rifampicin
rpoB 760727 c.921C>G synonymous_variant 0.9 rifampicin
rpoB 760841 c.1035T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760858 p.Val351Ala missense_variant 0.85 rifampicin Uncertain significance
rpoB 760862 c.1056G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760865 c.1059C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760886 p.Glu360Asp missense_variant 0.88 rifampicin Uncertain significance
rpoB 760887 p.Thr361Val missense_variant 0.89 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760928 c.1122G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.86 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.86 rifampicin
rpoB 761105 c.1299C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761171 c.1365C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761178 c.1372_1374delTCAinsAC frameshift_variant&missense_variant 0.93 rifampicin
rpoB 761186 p.Glu460Asp missense_variant 0.92 rifampicin Uncertain significance
rpoB 761189 c.1383T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761219 c.1413G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761234 c.1428G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761564 c.1758G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761612 c.1806G>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761990 c.2184G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762056 c.2250G>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762275 c.2469C>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 0.9 rifampicin Uncertain significance
rpoB 762894 c.3088C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762899 c.3093G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763082 c.3276C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763088 c.3282C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 763145 c.3339G>A synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 763157 c.3351G>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 763172 c.3366G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763531 c.162G>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.8 rifampicin
rpoC 763723 c.354G>C synonymous_variant 0.9 rifampicin
rpoC 763732 c.363C>A synonymous_variant 0.82 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.8 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.8 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.8 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.8 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.8 rifampicin
rpoC 764377 c.1008C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764534 c.1165C>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764542 c.1173C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764545 c.1176C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764560 c.1191T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764692 c.1323C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.89 rifampicin Not assoc w R
rpoC 764810 p.Pro481Ala missense_variant 0.88 rifampicin Uncertain significance
rpoC 764815 c.1446A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765861 p.Phe831Tyr missense_variant 0.82 rifampicin Uncertain significance
rpoC 765875 p.Val836Ile missense_variant 0.92 rifampicin Uncertain significance
rpoC 765907 c.2538G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765910 c.2541G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767080 c.3711G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767107 c.3738C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767125 c.3756G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767149 c.3780C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767179 c.3810C>T synonymous_variant 0.92 rifampicin
rpoC 767180 p.Ala1271Ser missense_variant 1.0 rifampicin Uncertain significance
rpoC 767191 c.3822C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767203 c.3834C>G synonymous_variant 1.0 rifampicin
rpoC 767206 c.3837C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 1.0 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpsL 781829 c.270G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781859 c.300T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rplC 800672 c.-137G>C upstream_gene_variant 0.92 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 0.92 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.92 linezolid
rplC 800703 c.-106_-104delTTGinsCC upstream_gene_variant 0.92 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.92 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.92 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.92 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 1.0 linezolid
atpE 1461132 p.Val30Ile missense_variant 0.5 bedaquiline
atpE 1461146 c.102G>T synonymous_variant 0.54 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.54 bedaquiline
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.6 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.77 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.77 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.35 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.42 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.31 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.31 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.29 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.3 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472846 n.1001C>T non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>A non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>T non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472861 n.1016G>A non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.74 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.75 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473082 n.1237G>A non_coding_transcript_exon_variant 0.62 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.74 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473129 n.1284C>T non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.85 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.79 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473770 n.113T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473812 n.155G>A non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1473814 n.157A>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1473839 n.182G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474089 n.432C>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1474100 n.443C>T non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1474103 n.446A>C non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1474106 n.449_450insCT non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1474109 n.453_454delAT non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524_525insT non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474184 n.527C>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474185 n.529delA non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474709 n.1052_1060delGTGGTGTAAinsAATAAGTTAG non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474743 n.1086T>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475061 n.1406delA non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475202 n.1545G>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>A non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1475443 n.1786G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475475 n.1818C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1475760 n.2105_2106delGC non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1475765 n.2108A>T non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.92 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475989 n.2332T>C non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.31 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>A non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.96 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476666 n.3009C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
inhA 1674903 c.702T>C synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 0.91 ethionamide
isoniazid
inhA 1674909 c.708G>A synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674912 c.711G>C synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674915 c.714C>G synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674942 c.741T>C synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674949 c.748C>T synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674954 c.753G>C synonymous_variant 0.9 ethionamide
isoniazid
rpsA 1833589 c.48A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 1.0 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 0.93 pyrazinamide
rpsA 1833616 c.75A>T synonymous_variant 0.94 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.94 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 0.95 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 0.92 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.75 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.77 pyrazinamide
rpsA 1833823 c.282G>A synonymous_variant 0.79 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.85 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.85 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.87 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.87 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.88 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.88 pyrazinamide
rpsA 1833874 c.333T>G synonymous_variant 0.88 pyrazinamide
rpsA 1833886 c.345C>G synonymous_variant 0.88 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.92 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.85 pyrazinamide
rpsA 1833961 c.420C>G synonymous_variant 0.85 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.92 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.93 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.92 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.89 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834033 c.492C>T synonymous_variant 0.89 pyrazinamide
rpsA 1834073 p.Lys178Arg missense_variant 0.92 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.91 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.91 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1834294 c.753G>T synonymous_variant 0.93 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 0.93 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.93 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834327 c.786G>T synonymous_variant 0.95 pyrazinamide
rpsA 1834357 c.816T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>C synonymous_variant 0.86 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834411 c.870T>G synonymous_variant 0.86 pyrazinamide
rpsA 1834414 c.873C>T synonymous_variant 0.8 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.79 pyrazinamide
rpsA 1834420 c.879C>T synonymous_variant 0.79 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.86 pyrazinamide
rpsA 1834429 c.888C>T synonymous_variant 0.85 pyrazinamide
rpsA 1834438 c.897C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834606 c.1065C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834720 c.1179C>G synonymous_variant 0.92 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 1.0 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 1.0 pyrazinamide
rpsA 1834774 c.1233C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 1.0 pyrazinamide
kasA 2517917 c.-198G>C upstream_gene_variant 0.83 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.9 isoniazid
kasA 2518768 c.654C>G synonymous_variant 0.9 isoniazid
kasA 2518771 c.657C>G synonymous_variant 0.9 isoniazid
kasA 2518774 c.660C>T synonymous_variant 0.82 isoniazid
kasA 2518783 c.669T>G synonymous_variant 0.82 isoniazid
kasA 2518787 p.Arg225Lys missense_variant 0.9 isoniazid
kasA 2518792 c.678C>T synonymous_variant 0.9 isoniazid
kasA 2518795 c.681C>T synonymous_variant 0.9 isoniazid
kasA 2518798 c.684G>C synonymous_variant 0.9 isoniazid
Rv2477c 2783344 c.699C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783347 c.696C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783356 c.687C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
mtrB 3625711 c.903C>T synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625720 c.894G>C synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625732 c.882C>T synonymous_variant 0.91 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625735 c.879C>A synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625744 c.870G>A synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625750 c.864G>A synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.91 bedaquiline
rifampicin Uncertain significance
mtrB 3625765 c.849C>G synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625774 c.840G>A synonymous_variant 0.91 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625783 c.-873C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625806 c.808A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625807 c.807C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626704 c.-91C>T upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3626711 c.-98T>C upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3626717 c.-104C>T upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrA 3626741 c.609C>G synonymous_variant 0.87 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627053 c.297C>T synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627056 c.294C>T synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627059 c.291G>T synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627068 c.282T>C synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627073 c.277C>T synonymous_variant 0.94 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrA 3627098 c.252A>C synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627110 c.-497G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627128 c.-515T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627133 p.Ala73Ser missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627139 c.-526T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627143 c.-530G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
rpoA 3877563 c.945C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877569 c.937_939delCCGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877593 c.915C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877614 c.894G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877620 c.888G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877665 c.843C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877677 c.831G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877896 c.612G>A synonymous_variant 1.0 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877929 c.577_579delATCinsGG frameshift_variant&missense_variant 0.93 rifampicin
rpoA 3878205 c.303T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878259 c.249G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878271 c.237T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878343 c.165C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.8 rifampicin
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038782 c.1923G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038795 p.Ser637Thr missense_variant 1.0 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038815 c.1890G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038838 c.1867C>T synonymous_variant 0.93 pyrazinamide
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 0.92 pyrazinamide
clpC1 4038857 c.1848C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.9 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039046 c.1659C>G synonymous_variant 0.72 pyrazinamide
clpC1 4039070 c.1635G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039077 p.Lys543Arg missense_variant 0.64 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 0.9 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 0.9 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.82 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039190 c.1515C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039196 c.1509G>A synonymous_variant 0.82 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 1.0 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.82 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039469 c.1236T>C synonymous_variant 0.9 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039478 c.1227G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.79 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.93 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.85 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039943 c.762G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039946 c.759A>G synonymous_variant 0.85 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.85 pyrazinamide
clpC1 4039957 c.748C>T synonymous_variant 0.85 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.85 pyrazinamide
clpC1 4039964 c.741C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039975 p.Asp244Asn missense_variant 0.92 pyrazinamide Uncertain significance
clpC1 4039979 c.726C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039982 c.723G>A synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040009 c.696C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040021 c.684A>T synonymous_variant 1.0 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040048 c.657C>T synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
glpK 4138601 c.1155G>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138607 c.1149G>T synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138610 c.1146C>G synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138616 c.1140G>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>A synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138631 c.1125C>G synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4240819 c.957A>C synonymous_variant 0.8 ethambutol
embC 4240826 p.Ala322Ser missense_variant 0.73 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.82 ethambutol