TB-Profiler result

Run: ERR4816548
Summary

Run ID: ERR4816548

Sample name:

Date: 01-04-2023 14:29:33

Number of reads: 659195

Percentage reads mapped: 26.96

Strain: lineage4.5

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761196 p.Leu464Met missense_variant 0.18 rifampicin
fabG1 1673425 c.-15C>T upstream_gene_variant 1.0 isoniazid, ethionamide
katG 2154347 p.Pro589Thr missense_variant 0.18 isoniazid
embB 4247619 p.Val369Ala missense_variant 0.22 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6763 c.-539G>A upstream_gene_variant 0.2
gyrA 6766 c.-536G>T upstream_gene_variant 0.2
gyrA 6775 c.-527G>T upstream_gene_variant 0.2
gyrA 6793 c.-509T>C upstream_gene_variant 0.18
gyrB 6797 p.Gly520Ser missense_variant 0.18
gyrA 6808 c.-494C>G upstream_gene_variant 0.2
gyrB 7261 p.Asp674Glu missense_variant 0.17
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 1.0
gyrA 8261 c.960C>G synonymous_variant 0.12
gyrA 8264 c.963T>C synonymous_variant 0.12
gyrA 8270 c.969G>C synonymous_variant 0.19
gyrA 8283 p.Ile328Leu missense_variant 0.33
gyrA 8288 c.987T>C synonymous_variant 0.4
gyrA 8294 c.993T>C synonymous_variant 0.43
gyrA 8316 p.Thr339Tyr missense_variant 0.38
gyrA 8320 p.Ser340Asn missense_variant 0.4
gyrA 8324 c.1023T>C synonymous_variant 0.38
gyrA 8329 p.Ala343Val missense_variant 0.38
gyrA 8339 c.1038A>G synonymous_variant 0.42
gyrA 8343 p.Ile348Leu missense_variant 0.4
gyrA 8354 c.1053G>C synonymous_variant 0.35
gyrA 8375 c.1074G>C synonymous_variant 0.25
gyrA 8382 p.Leu361Met missense_variant 0.24
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620029 c.139C>T synonymous_variant 1.0
rpoB 760130 p.Asp108Glu missense_variant 0.25
rpoB 760139 c.333A>C synonymous_variant 0.25
rpoB 760140 p.Pro112Ser missense_variant 0.26
rpoB 760148 p.Asp114Glu missense_variant 0.25
rpoB 760157 c.351A>G synonymous_variant 0.38
rpoB 760181 c.375T>G synonymous_variant 0.53
rpoB 760184 c.378A>G synonymous_variant 0.53
rpoB 760206 p.Ile134Val missense_variant 0.47
rpoB 760223 c.417T>C synonymous_variant 0.48
rpoB 760235 c.429T>C synonymous_variant 0.48
rpoB 760244 c.438G>C synonymous_variant 0.62
rpoB 760253 c.447T>C synonymous_variant 0.56
rpoB 760262 c.456G>C synonymous_variant 0.5
rpoB 760263 p.Met153Val missense_variant 0.5
rpoB 760274 p.Glu156Asp missense_variant 0.59
rpoB 760298 c.492G>C synonymous_variant 0.57
rpoB 760310 c.504G>C synonymous_variant 0.57
rpoB 760313 c.507G>C synonymous_variant 0.54
rpoB 760316 c.510C>G synonymous_variant 0.53
rpoB 760317 c.511_512delAGinsTC synonymous_variant 0.53
rpoB 760325 c.519G>C synonymous_variant 0.53
rpoB 760340 c.534G>C synonymous_variant 0.54
rpoB 760353 p.Glu183Gln missense_variant 0.36
rpoB 760356 p.Thr184Ala missense_variant 0.35
rpoB 760361 c.555T>C synonymous_variant 0.42
rpoB 760370 c.564C>G synonymous_variant 0.31
rpoB 760398 p.Val198Ile missense_variant 0.3
rpoB 760403 c.597C>T synonymous_variant 0.3
rpoB 760412 c.606C>G synonymous_variant 0.55
rpoB 760415 c.609C>T synonymous_variant 0.55
rpoB 760430 c.624T>C synonymous_variant 0.73
rpoB 760475 c.669A>G synonymous_variant 0.57
rpoB 760481 c.675G>C synonymous_variant 0.55
rpoB 760484 c.678A>G synonymous_variant 0.52
rpoB 760502 c.696C>G synonymous_variant 0.33
rpoB 760508 c.702G>C synonymous_variant 0.3
rpoB 760511 c.705G>C synonymous_variant 0.26
rpoB 760598 c.792C>G synonymous_variant 0.12
rpoB 760611 c.805T>C synonymous_variant 0.32
rpoB 760634 c.828T>C synonymous_variant 0.39
rpoB 760646 c.840C>G synonymous_variant 0.39
rpoB 760652 c.846C>G synonymous_variant 0.37
rpoB 760655 c.849A>G synonymous_variant 0.37
rpoB 760659 c.853_855delTCAinsAGC synonymous_variant 0.37
rpoB 760673 c.867G>C synonymous_variant 0.37
rpoB 760674 c.868T>C synonymous_variant 0.33
rpoB 760679 c.873A>G synonymous_variant 0.33
rpoB 760683 c.877T>C synonymous_variant 0.33
rpoB 760697 p.Glu297Asp missense_variant 0.2
rpoB 760916 c.1110C>T synonymous_variant 0.25
rpoB 760919 c.1113C>T synonymous_variant 0.25
rpoB 760925 c.1119T>C synonymous_variant 0.25
rpoB 760946 c.1140A>G synonymous_variant 0.33
rpoB 760965 p.Met387Leu missense_variant 0.36
rpoB 760982 c.1176G>C synonymous_variant 0.25
rpoB 760985 c.1179G>C synonymous_variant 0.27
rpoB 760988 c.1182C>G synonymous_variant 0.24
rpoB 760991 c.1185G>C synonymous_variant 0.24
rpoB 760997 c.1191G>C synonymous_variant 0.24
rpoB 761003 c.1197C>G synonymous_variant 0.24
rpoB 761015 c.1209G>C synonymous_variant 0.2
rpoB 761027 c.1221A>G synonymous_variant 0.2
rpoB 761132 c.1326G>T synonymous_variant 0.21
rpoB 761133 c.1327T>C synonymous_variant 0.22
rpoB 761147 c.1341C>T synonymous_variant 0.25
rpoB 761150 c.1344A>C synonymous_variant 0.24
rpoB 761165 c.1359G>C synonymous_variant 0.21
rpoB 761168 c.1362C>G synonymous_variant 0.21
rpoB 761171 c.1365C>T synonymous_variant 0.2
rpoB 761180 c.1374A>C synonymous_variant 0.19
rpoB 761192 c.1386C>G synonymous_variant 0.19
rpoB 761195 c.1389G>C synonymous_variant 0.17
rpoB 761201 p.Glu465Asp missense_variant 0.18
rpoB 761537 c.1731C>G synonymous_variant 0.16
rpoB 761540 c.1734C>G synonymous_variant 0.16
rpoB 761552 c.1746G>C synonymous_variant 0.15
rpoB 761558 c.1752C>G synonymous_variant 0.15
rpoB 761564 c.1758G>C synonymous_variant 0.14
rpoB 761603 c.1797C>G synonymous_variant 0.22
rpoB 761612 c.1806G>T synonymous_variant 0.21
rpoB 761615 c.1809A>C synonymous_variant 0.21
rpoB 762053 c.2247T>C synonymous_variant 0.21
rpoB 762062 c.2256T>C synonymous_variant 0.32
rpoB 762065 c.2259T>C synonymous_variant 0.3
rpoB 762080 c.2274G>C synonymous_variant 0.27
rpoB 762086 c.2280G>C synonymous_variant 0.29
rpoB 762099 c.2293_2295delCGCinsAGG synonymous_variant 0.39
rpoB 762114 p.Ile770Val missense_variant 0.49
rpoB 762122 p.Asp772Glu missense_variant 0.55
rpoB 762125 p.Glu773Asp missense_variant 0.5
rpoB 762131 c.2325C>G synonymous_variant 0.54
rpoB 762140 c.2334G>C synonymous_variant 0.57
rpoB 762143 c.2337T>C synonymous_variant 0.58
rpoB 762149 c.2343G>C synonymous_variant 0.62
rpoB 762156 p.Val784Ile missense_variant 0.62
rpoB 762176 c.2370T>C synonymous_variant 0.64
rpoB 762185 c.2379G>C synonymous_variant 0.68
rpoB 762209 c.2403C>G synonymous_variant 0.71
rpoB 762218 c.2412T>C synonymous_variant 0.65
rpoB 762233 c.2427G>C synonymous_variant 0.72
rpoB 762245 c.2439G>C synonymous_variant 0.72
rpoB 762254 c.2448T>C synonymous_variant 0.71
rpoB 762257 c.2451C>G synonymous_variant 0.68
rpoB 762266 c.2460T>C synonymous_variant 0.69
rpoB 762293 c.2487T>C synonymous_variant 0.67
rpoB 762317 c.2511A>G synonymous_variant 0.63
rpoB 762318 p.Ser838Thr missense_variant 0.63
rpoB 762329 c.2523G>C synonymous_variant 0.65
rpoB 762338 c.2532T>C synonymous_variant 0.59
rpoB 762341 c.2535G>C synonymous_variant 0.52
rpoB 762347 c.2541T>C synonymous_variant 0.5
rpoB 762359 p.Asp851Glu missense_variant 0.45
rpoB 762362 p.Glu852Asp missense_variant 0.43
rpoB 762369 c.2563T>C synonymous_variant 0.38
rpoC 762374 c.-996G>C upstream_gene_variant 0.35
rpoB 762375 p.Ala857Pro missense_variant 0.32
rpoC 762380 c.-990T>C upstream_gene_variant 0.3
rpoC 762392 c.-978G>C upstream_gene_variant 0.17
rpoC 762836 c.-534C>T upstream_gene_variant 0.16
rpoC 762857 c.-513C>G upstream_gene_variant 0.32
rpoB 762858 p.Thr1018Ala missense_variant 0.32
rpoC 762863 c.-507T>C upstream_gene_variant 0.32
rpoB 762878 p.Ile1024Met missense_variant 0.48
rpoB 762879 p.Met1025Leu missense_variant 0.48
rpoB 762894 p.Leu1030Met missense_variant 0.52
rpoC 762917 c.-453C>G upstream_gene_variant 0.62
rpoC 762920 c.-450C>G upstream_gene_variant 0.64
rpoC 762926 c.-444C>G upstream_gene_variant 0.64
rpoC 762929 c.-441G>C upstream_gene_variant 0.63
rpoC 762947 c.-423C>G upstream_gene_variant 0.57
rpoC 762959 c.-411G>C upstream_gene_variant 0.61
rpoC 762962 c.-408C>T upstream_gene_variant 0.61
rpoC 762989 c.-381G>C upstream_gene_variant 0.57
rpoC 762995 c.-375G>C upstream_gene_variant 0.59
rpoC 763013 c.-357C>G upstream_gene_variant 0.53
rpoC 763028 c.-342T>C upstream_gene_variant 0.39
rpoC 763031 c.-339T>G upstream_gene_variant 0.38
rpoC 763034 c.-336C>G upstream_gene_variant 0.37
rpoC 763040 c.-330C>G upstream_gene_variant 0.33
rpoC 763053 c.-317_-315delTTGinsCTC upstream_gene_variant 0.15
rpoC 763465 c.96G>A synonymous_variant 0.13
rpoC 763468 c.99G>C synonymous_variant 0.2
rpoC 763483 c.114G>C synonymous_variant 0.32
rpoC 763486 c.117T>G synonymous_variant 0.3
rpoC 763504 c.135C>A synonymous_variant 0.42
rpoC 763507 c.138G>C synonymous_variant 0.52
rpoC 763528 c.159G>T synonymous_variant 0.58
rpoC 763534 c.165T>C synonymous_variant 0.62
rpoC 763537 c.168C>G synonymous_variant 0.63
rpoC 763546 c.177A>G synonymous_variant 0.69
rpoC 763570 c.201G>C synonymous_variant 0.79
rpoC 763603 c.234C>T synonymous_variant 0.8
rpoC 763606 c.237C>T synonymous_variant 0.8
rpoC 763615 c.246G>C synonymous_variant 0.77
rpoC 763618 c.249C>G synonymous_variant 0.77
rpoC 763621 c.252C>T synonymous_variant 0.77
rpoC 763633 c.264T>C synonymous_variant 0.76
rpoC 763660 c.291T>G synonymous_variant 0.7
rpoC 763666 c.297G>C synonymous_variant 0.68
rpoC 763669 c.300C>G synonymous_variant 0.63
rpoC 763675 c.306C>G synonymous_variant 0.67
rpoC 763699 c.330G>T synonymous_variant 0.57
rpoC 763711 c.342G>C synonymous_variant 0.52
rpoC 763714 c.345G>C synonymous_variant 0.51
rpoC 763717 c.348T>C synonymous_variant 0.52
rpoC 763744 c.375G>C synonymous_variant 0.46
rpoC 763765 c.396T>G synonymous_variant 0.39
rpoC 763768 c.399C>G synonymous_variant 0.39
rpoC 764098 c.729A>G synonymous_variant 0.15
rpoC 764099 c.730_732delCTCinsTTG synonymous_variant 0.15
rpoC 764110 c.741C>T synonymous_variant 0.27
rpoC 764131 c.762T>C synonymous_variant 0.36
rpoC 764133 p.Ala255Gly missense_variant 0.36
rpoC 764143 c.774G>C synonymous_variant 0.33
rpoC 764147 p.Ser260Ala missense_variant 0.36
rpoC 764162 p.Ile265Ala missense_variant 0.42
rpoC 764168 p.Asn267Asp missense_variant 0.33
rpoC 764177 p.Ile270Val missense_variant 0.36
rpoC 764188 c.819A>G synonymous_variant 0.27
rpoC 764195 p.Ser276Ala missense_variant 0.2
rpoC 764338 c.969G>A synonymous_variant 0.32
rpoC 764365 c.996C>T synonymous_variant 0.46
rpoC 764371 c.1002G>C synonymous_variant 0.46
rpoC 764383 c.1014C>G synonymous_variant 0.41
rpoC 764387 c.1018T>C synonymous_variant 0.41
rpoC 764405 c.1036A>C synonymous_variant 0.5
rpoC 764410 c.1041G>C synonymous_variant 0.54
rpoC 764428 c.1059G>C synonymous_variant 0.48
rpoC 764431 c.1062G>C synonymous_variant 0.46
rpoC 764434 c.1065A>G synonymous_variant 0.43
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.43
rpoC 764446 c.1077T>C synonymous_variant 0.5
rpoC 764449 c.1080G>C synonymous_variant 0.5
rpoC 764452 c.1083T>C synonymous_variant 0.5
rpoC 764458 c.1089G>C synonymous_variant 0.5
rpoC 764461 c.1092A>G synonymous_variant 0.5
rpoC 764497 c.1128A>G synonymous_variant 0.44
rpoC 764503 c.1134G>C synonymous_variant 0.56
rpoC 764521 c.1152T>C synonymous_variant 0.69
rpoC 764527 c.1158C>T synonymous_variant 0.69
rpoC 764533 c.1164C>A synonymous_variant 0.69
rpoC 764536 c.1167G>T synonymous_variant 0.65
rpoC 764539 c.1170C>G synonymous_variant 0.65
rpoC 764542 c.1173C>G synonymous_variant 0.65
rpoC 764548 c.1179G>T synonymous_variant 0.65
rpoC 764551 c.1182G>C synonymous_variant 0.65
rpoC 764554 c.1185C>T synonymous_variant 0.67
rpoC 764560 c.1191T>G synonymous_variant 0.68
rpoC 764566 c.1197C>G synonymous_variant 0.68
rpoC 764575 c.1206T>G synonymous_variant 0.67
rpoC 764581 c.1212T>C synonymous_variant 0.65
rpoC 764605 c.1236G>C synonymous_variant 0.77
rpoC 764611 c.1242G>T synonymous_variant 0.74
rpoC 764626 c.1257C>T synonymous_variant 0.67
rpoC 764632 c.1263T>C synonymous_variant 0.77
rpoC 764644 c.1275G>C synonymous_variant 0.77
rpoC 764650 c.1281G>T synonymous_variant 0.77
rpoC 764660 p.Val431Ile missense_variant 0.7
rpoC 764668 c.1299C>T synonymous_variant 0.72
rpoC 764701 c.1332C>G synonymous_variant 0.61
rpoC 764705 p.Leu446Asp missense_variant 0.59
rpoC 764716 c.1347G>C synonymous_variant 0.56
rpoC 764737 c.1368G>C synonymous_variant 0.44
rpoC 764764 c.1395T>C synonymous_variant 0.38
rpoC 764780 c.1411_1412delAGinsTC synonymous_variant 0.18
rpoC 764896 c.1527C>T synonymous_variant 0.24
rpoC 764911 c.1542A>G synonymous_variant 0.25
rpoC 764912 p.Met515Gln missense_variant 0.24
rpoC 764935 c.1566T>C synonymous_variant 0.25
rpoC 764948 c.1579T>C synonymous_variant 0.25
rpoC 764953 c.1584G>C synonymous_variant 0.26
rpoC 764956 c.1587T>C synonymous_variant 0.3
rpoC 764968 c.1599T>C synonymous_variant 0.29
rpoC 764971 c.1602C>G synonymous_variant 0.29
rpoC 765813 p.Arg815Gln missense_variant 0.15
rpoC 766588 p.Glu1073Asp missense_variant 0.17
rpoC 766957 p.Glu1196Asp missense_variant 0.17
rpoC 766996 c.3627C>T synonymous_variant 0.4
rpoC 767008 c.3639G>C synonymous_variant 0.62
rpoC 767015 p.Ala1216Thr missense_variant 0.59
rpoC 767020 c.3651C>G synonymous_variant 0.57
rpoC 767038 c.3669G>C synonymous_variant 0.56
rpoC 767059 c.3690T>G synonymous_variant 0.54
rpoC 767062 c.3693C>T synonymous_variant 0.48
rpoC 767065 c.3696G>C synonymous_variant 0.48
rpoC 767074 c.3705T>C synonymous_variant 0.4
rpoC 767077 c.3708G>C synonymous_variant 0.38
rpoC 767087 p.Cys1240Gly missense_variant 0.33
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776922 p.Ala520Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781751 c.192G>C synonymous_variant 0.28
rpsL 781754 c.195G>C synonymous_variant 0.26
rpsL 781760 c.201T>C synonymous_variant 0.22
rpsL 781763 c.204C>G synonymous_variant 0.25
rpsL 781802 c.243G>C synonymous_variant 0.38
rpsL 781811 c.252C>T synonymous_variant 0.39
rpsL 781814 c.255C>T synonymous_variant 0.38
rpsL 781817 c.258G>T synonymous_variant 0.35
rpsL 781829 c.270G>C synonymous_variant 0.38
rpsL 781832 c.273T>C synonymous_variant 0.43
rpsL 781838 c.279G>C synonymous_variant 0.45
rpsL 781851 p.Ile98Val missense_variant 0.48
rpsL 781865 c.306G>C synonymous_variant 0.6
rpsL 781868 c.309T>C synonymous_variant 0.56
rpsL 781877 c.318T>C synonymous_variant 0.57
rpsL 781880 c.321C>G synonymous_variant 0.48
rpsL 781892 c.333A>G synonymous_variant 0.43
rpsL 781898 c.339A>G synonymous_variant 0.43
rpsL 781907 c.348T>G synonymous_variant 0.42
rpsL 781929 p.Gly124Ser missense_variant 0.35
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.29
rplC 800672 c.-137G>C upstream_gene_variant 0.24
rplC 800690 c.-119C>T upstream_gene_variant 0.33
rplC 800693 c.-116A>G upstream_gene_variant 0.4
rplC 800703 c.-106T>C upstream_gene_variant 0.42
rplC 800715 c.-94_-92delATCinsGTG upstream_gene_variant 0.47
rplC 800720 c.-89T>C upstream_gene_variant 0.5
rplC 800723 c.-86C>G upstream_gene_variant 0.47
rplC 800735 c.-74C>G upstream_gene_variant 0.38
rplC 800738 c.-71T>C upstream_gene_variant 0.38
rplC 800762 c.-47T>G upstream_gene_variant 0.21
rplC 800771 c.-38C>T upstream_gene_variant 0.21
rplC 800780 c.-29C>G upstream_gene_variant 0.24
fbiC 1305191 p.Ala754Val missense_variant 0.2
Rv1258c 1406101 p.Pro414Ser missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.57
rrs 1472123 n.278A>G non_coding_transcript_exon_variant 0.63
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.63
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.64
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.64
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.68
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.59
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.33
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.28
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.28
rrs 1472296 n.454_458delTCCGG non_coding_transcript_exon_variant 0.25
rrs 1472305 n.461_467delTCTCTCG non_coding_transcript_exon_variant 0.29
rrs 1472315 n.470_471insAC non_coding_transcript_exon_variant 0.29
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.4
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.38
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.71
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.59
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.45
rrs 1472426 n.581T>G non_coding_transcript_exon_variant 0.28
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.12
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.26
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.3
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.3
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.25
rrs 1472494 n.649A>T non_coding_transcript_exon_variant 0.27
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.32
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.63
rrs 1472583 n.738T>A non_coding_transcript_exon_variant 0.58
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.62
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.51
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.55
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.47
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.47
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.42
rrs 1472675 n.830T>G non_coding_transcript_exon_variant 0.36
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.36
rrs 1472678 n.833T>G non_coding_transcript_exon_variant 0.36
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.36
rrs 1472685 n.840G>T non_coding_transcript_exon_variant 0.36
rrs 1472686 n.841G>A non_coding_transcript_exon_variant 0.36
rrs 1472687 n.842A>C non_coding_transcript_exon_variant 0.42
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.56
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.57
rrs 1472843 n.998_999insT non_coding_transcript_exon_variant 0.6
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.58
rrs 1472849 n.1005delT non_coding_transcript_exon_variant 0.58
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.6
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.63
rrs 1472861 n.1016G>T non_coding_transcript_exon_variant 0.64
rrs 1472873 n.1028C>T non_coding_transcript_exon_variant 0.67
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.64
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.6
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.5
rrs 1472959 n.1114T>C non_coding_transcript_exon_variant 0.5
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.46
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.46
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.5
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.46
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.48
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.75
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.74
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.71
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.63
rrs 1473094 n.1249T>G non_coding_transcript_exon_variant 0.65
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.71
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.75
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.69
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.69
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.72
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.73
rrs 1473129 n.1284C>T non_coding_transcript_exon_variant 0.7
rrs 1473147 n.1302G>T non_coding_transcript_exon_variant 0.68
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.67
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.73
rrs 1473164 n.1319C>G non_coding_transcript_exon_variant 0.73
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.65
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.61
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.6
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.56
rrs 1473292 n.1447_1448insA non_coding_transcript_exon_variant 0.57
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.59
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.59
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.55
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.54
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.21
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.24
rrl 1473793 n.136G>C non_coding_transcript_exon_variant 0.22
rrl 1473794 n.137A>C non_coding_transcript_exon_variant 0.22
rrl 1473801 n.144T>G non_coding_transcript_exon_variant 0.21
rrl 1473802 n.145C>G non_coding_transcript_exon_variant 0.24
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.24
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.24
rrl 1473814 n.157A>G non_coding_transcript_exon_variant 0.25
rrl 1473815 n.158T>C non_coding_transcript_exon_variant 0.25
rrl 1473822 n.165A>G non_coding_transcript_exon_variant 0.26
rrl 1473830 n.173T>C non_coding_transcript_exon_variant 0.29
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.28
rrl 1473833 n.176_177insT non_coding_transcript_exon_variant 0.29
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.27
rrl 1473886 n.229A>C non_coding_transcript_exon_variant 0.27
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.27
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.27
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.27
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.22
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.24
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.23
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.38
rrl 1474163 n.506C>T non_coding_transcript_exon_variant 0.52
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.58
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.61
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.61
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.61
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.62
rrl 1474202 n.545T>G non_coding_transcript_exon_variant 0.6
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.65
rrl 1474220 n.563G>A non_coding_transcript_exon_variant 0.61
rrl 1474271 n.614A>G non_coding_transcript_exon_variant 0.24
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.22
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.2
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.19
rrl 1474349 n.692A>C non_coding_transcript_exon_variant 0.19
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.17
rrl 1474353 n.696A>C non_coding_transcript_exon_variant 0.17
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.18
rrl 1474355 n.698A>G non_coding_transcript_exon_variant 0.18
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.18
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.23
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.23
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.21
rrl 1474406 n.749T>G non_coding_transcript_exon_variant 0.19
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.13
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.16
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.14
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.14
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.21
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.39
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.16
rrl 1474628 n.971C>T non_coding_transcript_exon_variant 0.22
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.22
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.4
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.16
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.16
rrl 1474638 n.981C>T non_coding_transcript_exon_variant 0.27
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.17
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.23
rrl 1474643 n.986A>G non_coding_transcript_exon_variant 0.23
rrl 1474658 n.1001A>G non_coding_transcript_exon_variant 0.23
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.48
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.25
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.2
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.2
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.14
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.12
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.21
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.27
rrl 1474777 n.1120T>A non_coding_transcript_exon_variant 0.15
rrl 1474779 n.1122G>T non_coding_transcript_exon_variant 0.23
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.36
rrl 1474798 n.1141C>T non_coding_transcript_exon_variant 0.28
rrl 1474806 n.1149A>T non_coding_transcript_exon_variant 0.29
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.39
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.29
rrl 1474825 n.1168G>A non_coding_transcript_exon_variant 0.27
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.3
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.3
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.3
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.38
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.2
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.33
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.13
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.13
rrl 1474928 n.1271C>G non_coding_transcript_exon_variant 0.17
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.18
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 0.14
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.25
rrl 1475113 n.1456C>T non_coding_transcript_exon_variant 0.5
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.54
rrl 1475115 n.1458A>G non_coding_transcript_exon_variant 0.5
rrl 1475116 n.1459G>T non_coding_transcript_exon_variant 0.52
rrl 1475153 n.1496A>T non_coding_transcript_exon_variant 0.48
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 0.43
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.32
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.33
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.31
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.31
rrl 1475542 n.1885A>G non_coding_transcript_exon_variant 0.29
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.32
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.3
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.3
rrl 1475571 n.1914A>T non_coding_transcript_exon_variant 0.25
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.12
rrl 1475688 n.2031G>A non_coding_transcript_exon_variant 0.39
rrl 1475696 n.2039T>A non_coding_transcript_exon_variant 0.44
rrl 1475703 n.2046A>T non_coding_transcript_exon_variant 0.51
rrl 1475707 n.2050T>G non_coding_transcript_exon_variant 0.51
rrl 1475713 n.2056C>T non_coding_transcript_exon_variant 0.62
rrl 1475740 n.2083G>C non_coding_transcript_exon_variant 0.67
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.66
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.67
rrl 1475788 n.2131C>G non_coding_transcript_exon_variant 0.68
rrl 1475880 n.2223C>T non_coding_transcript_exon_variant 0.65
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.65
rrl 1475883 n.2226A>G non_coding_transcript_exon_variant 0.64
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.64
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.65
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.65
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.65
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.58
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.62
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.54
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.49
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.54
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.54
rrl 1475990 n.2333G>T non_coding_transcript_exon_variant 0.47
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.49
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.55
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.41
rrl 1476032 n.2375C>G non_coding_transcript_exon_variant 0.39
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.39
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.4
rrl 1476040 n.2383C>T non_coding_transcript_exon_variant 0.39
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.39
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.38
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.39
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.41
rrl 1476081 n.2424A>G non_coding_transcript_exon_variant 0.37
rrl 1476082 n.2425T>C non_coding_transcript_exon_variant 0.34
rrl 1476087 n.2430C>A non_coding_transcript_exon_variant 0.36
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.26
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.27
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 0.3
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.33
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.4
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.42
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.41
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.4
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.43
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.41
rrl 1476196 n.2539C>T non_coding_transcript_exon_variant 0.39
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.42
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.42
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.41
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.47
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.46
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.52
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.54
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.5
rrl 1476255 n.2598A>G non_coding_transcript_exon_variant 0.5
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.49
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.51
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.54
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.56
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.57
rrl 1476301 n.2644A>G non_coding_transcript_exon_variant 0.58
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.73
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.75
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.77
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.75
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.84
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.77
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.77
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 0.77
rrl 1476534 n.2877A>C non_coding_transcript_exon_variant 0.77
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.77
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.75
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.58
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.57
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.57
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.4
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.33
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.24
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.26
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.24
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.23
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.23
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.23
rrl 1476645 n.2988A>G non_coding_transcript_exon_variant 0.24
rpsA 1833628 c.87G>C synonymous_variant 0.15
rpsA 1833649 c.108C>T synonymous_variant 0.15
rpsA 1833667 c.126C>G synonymous_variant 0.14
rpsA 1833676 c.135A>G synonymous_variant 0.14
rpsA 1833679 c.138G>C synonymous_variant 0.17
rpsA 1833685 c.144G>T synonymous_variant 0.21
rpsA 1833691 c.150G>A synonymous_variant 0.13
rpsA 1833697 c.156C>G synonymous_variant 0.13
rpsA 1833709 c.168C>T synonymous_variant 0.19
rpsA 1833721 c.180A>G synonymous_variant 0.24
rpsA 1833727 c.186G>C synonymous_variant 0.21
rpsA 1833730 c.189C>T synonymous_variant 0.16
rpsA 1833734 p.Ala65Ser missense_variant 0.16
rpsA 1833745 c.204G>C synonymous_variant 0.18
rpsA 1833769 c.228C>G synonymous_variant 0.19
rpsA 1833771 p.Asn77Thr missense_variant 0.18
rpsA 1833829 c.288A>G synonymous_variant 0.19
rpsA 1833832 c.291G>A synonymous_variant 0.24
rpsA 1833838 c.297G>T synonymous_variant 0.23
rpsA 1833841 c.300C>G synonymous_variant 0.23
rpsA 1833847 c.306C>G synonymous_variant 0.31
rpsA 1833856 c.315A>G synonymous_variant 0.3
rpsA 1833862 c.321G>C synonymous_variant 0.33
rpsA 1833874 c.333T>C synonymous_variant 0.39
rpsA 1833886 c.345C>G synonymous_variant 0.4
rpsA 1833894 p.Ala118Glu missense_variant 0.41
rpsA 1833914 p.Ala125Pro missense_variant 0.44
rpsA 1833928 c.387G>C synonymous_variant 0.44
rpsA 1833949 c.408T>C synonymous_variant 0.49
rpsA 1833955 c.414G>C synonymous_variant 0.51
rpsA 1833970 c.429G>C synonymous_variant 0.52
rpsA 1833973 c.432G>C synonymous_variant 0.54
rpsA 1833979 c.438T>C synonymous_variant 0.54
rpsA 1834000 c.459G>C synonymous_variant 0.61
rpsA 1834012 c.471G>C synonymous_variant 0.6
rpsA 1834030 c.489C>G synonymous_variant 0.61
rpsA 1834034 p.Ile165Val missense_variant 0.57
rpsA 1834040 p.Lys167Arg missense_variant 0.51
rpsA 1834046 p.Ile169Leu missense_variant 0.51
rpsA 1834093 c.552G>C synonymous_variant 0.36
rpsA 1834110 p.Trp190Tyr missense_variant 0.18
rpsA 1834172 p.Ile211Val missense_variant 0.14
rpsA 1834177 c.636A>C synonymous_variant 0.13
rpsA 1834183 c.642T>C synonymous_variant 0.16
rpsA 1834189 c.648G>C synonymous_variant 0.21
rpsA 1834210 c.669C>T synonymous_variant 0.31
rpsA 1834219 c.678C>G synonymous_variant 0.26
rpsA 1834222 c.681T>C synonymous_variant 0.27
rpsA 1834231 c.690T>C synonymous_variant 0.29
rpsA 1834234 c.693G>C synonymous_variant 0.3
rpsA 1834240 c.699T>C synonymous_variant 0.39
rpsA 1834249 c.708T>C synonymous_variant 0.47
rpsA 1834255 c.714C>G synonymous_variant 0.56
rpsA 1834261 c.720A>G synonymous_variant 0.56
rpsA 1834264 c.723G>C synonymous_variant 0.57
rpsA 1834294 c.753G>C synonymous_variant 0.46
rpsA 1834298 p.Gln253Glu missense_variant 0.43
rpsA 1834303 c.762T>C synonymous_variant 0.43
rpsA 1834306 c.765T>C synonymous_variant 0.42
rpsA 1834307 p.Asp256Gln missense_variant 0.42
rpsA 1834318 c.777C>G synonymous_variant 0.44
rpsA 1834327 c.786G>C synonymous_variant 0.41
rpsA 1834333 p.Asp264Glu missense_variant 0.38
rpsA 1834336 c.795C>G synonymous_variant 0.34
rpsA 1834348 c.807T>C synonymous_variant 0.21
rpsA 1834396 c.855G>T synonymous_variant 0.25
rpsA 1834399 p.His286Gln missense_variant 0.32
rpsA 1834411 c.870T>C synonymous_variant 0.4
rpsA 1834423 c.882G>C synonymous_variant 0.41
rpsA 1834451 c.910_912delTTGinsCTC synonymous_variant 0.48
rpsA 1834456 c.915T>C synonymous_variant 0.46
rpsA 1834465 c.924T>C synonymous_variant 0.46
rpsA 1834468 c.927A>G synonymous_variant 0.48
rpsA 1834489 c.948T>C synonymous_variant 0.45
rpsA 1834670 p.Lys377Gln missense_variant 0.2
rpsA 1834686 p.Asp382Ala missense_variant 0.18
rpsA 1834688 p.Ser383Glu missense_variant 0.18
rpsA 1834716 p.Phe392Tyr missense_variant 0.16
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2103101 c.-59C>A upstream_gene_variant 1.0
katG 2154228 p.Val628Leu missense_variant 0.15
katG 2154246 c.1866T>G synonymous_variant 0.21
katG 2154249 c.1863C>G synonymous_variant 0.21
katG 2154252 p.Ser620Thr missense_variant 0.21
katG 2154255 c.1857C>G synonymous_variant 0.2
katG 2154261 c.1851T>G synonymous_variant 0.18
katG 2154281 p.Leu611Ile missense_variant 0.19
katG 2154286 p.Met609Ala missense_variant 0.2
katG 2154297 c.1815G>C synonymous_variant 0.22
katG 2154302 c.1810T>C synonymous_variant 0.24
katG 2155601 p.Cys171Arg missense_variant 0.19
katG 2155608 c.504C>G synonymous_variant 0.18
katG 2155617 p.Ile165Met missense_variant 0.18
katG 2155626 c.486G>C synonymous_variant 0.18
katG 2155632 c.480A>G synonymous_variant 0.14
katG 2155636 p.Leu159Ile missense_variant 0.21
katG 2155659 c.453C>G synonymous_variant 0.39
katG 2155674 c.438G>T synonymous_variant 0.25
katG 2155677 c.435C>T synonymous_variant 0.26
katG 2155691 c.421T>C synonymous_variant 0.33
katG 2155696 p.Ala139Val missense_variant 0.3
katG 2155704 c.408C>G synonymous_variant 0.33
katG 2155716 c.396T>C synonymous_variant 0.35
katG 2155722 c.390G>C synonymous_variant 0.38
katG 2155728 c.384G>C synonymous_variant 0.33
PPE35 2167781 c.2832C>T synonymous_variant 0.18
PPE35 2168908 p.Thr569Ser missense_variant 0.13
PPE35 2170568 p.Ile15Met missense_variant 1.0
Rv1979c 2222371 p.Ala265Glu missense_variant 0.2
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2288760 p.Ala161Val missense_variant 0.12
kasA 2517921 c.-194A>G upstream_gene_variant 0.13
kasA 2517934 c.-181A>T upstream_gene_variant 0.17
kasA 2517941 c.-174C>G upstream_gene_variant 0.15
kasA 2517950 c.-165C>G upstream_gene_variant 0.18
Rv2752c 3064865 p.Pro443Thr missense_variant 0.18
Rv2752c 3067117 c.-926C>T upstream_gene_variant 0.12
thyX 3067619 c.327A>G synonymous_variant 0.33
thyX 3067625 c.321C>G synonymous_variant 0.29
thyX 3067631 c.315C>A synonymous_variant 0.33
thyX 3067640 c.306G>A synonymous_variant 0.33
thyX 3067652 c.294T>C synonymous_variant 0.33
thyX 3067679 p.Cys89Val missense_variant 0.26
thyX 3067694 c.252G>C synonymous_variant 0.24
thyX 3067697 c.249C>G synonymous_variant 0.24
thyX 3067709 c.237G>C synonymous_variant 0.14
thyA 3073863 c.609T>C synonymous_variant 0.21
thyA 3073874 p.Ile200Val missense_variant 0.18
thyA 3073878 p.Glu198Asp missense_variant 0.2
thyA 3073888 p.Ser195Glu missense_variant 0.18
thyA 3073892 c.580T>C synonymous_variant 0.2
thyA 3073893 c.579C>A synonymous_variant 0.2
thyA 3073897 p.Ala192Val missense_variant 0.19
thyA 3073903 p.Ala190Asp missense_variant 0.24
thyA 3073908 p.Met188Ile missense_variant 0.24
thyA 3073920 c.552C>G synonymous_variant 0.25
thyA 3073925 c.547T>C synonymous_variant 0.21
thyA 3073926 c.546G>C synonymous_variant 0.21
thyA 3073929 c.543T>C synonymous_variant 0.2
thyA 3073935 c.537C>G synonymous_variant 0.26
thyA 3073953 c.519T>C synonymous_variant 0.24
thyA 3073959 c.513T>C synonymous_variant 0.25
thyA 3073968 c.504C>G synonymous_variant 0.31
thyA 3073977 c.495A>G synonymous_variant 0.29
thyA 3073983 c.489C>G synonymous_variant 0.28
thyA 3073993 c.478_479delAGinsTC synonymous_variant 0.24
thyA 3073999 p.Arg158Gln missense_variant 0.22
thyA 3074001 c.471C>G synonymous_variant 0.21
thyA 3074004 c.468T>C synonymous_variant 0.21
thyA 3074031 c.441T>C synonymous_variant 0.29
thyA 3074034 c.438T>C synonymous_variant 0.29
thyA 3074037 c.435C>G synonymous_variant 0.26
thyA 3074053 p.Arg140Gln missense_variant 0.23
thyA 3074056 p.Glu139Pro missense_variant 0.23
thyA 3074058 c.414C>T synonymous_variant 0.23
thyA 3074061 p.Glu137Asp missense_variant 0.23
thyA 3074065 p.Gly136Ala missense_variant 0.23
thyA 3074076 c.396C>G synonymous_variant 0.23
thyA 3074079 c.393G>C synonymous_variant 0.25
thyA 3074091 c.381C>G synonymous_variant 0.25
thyA 3074100 c.372T>C synonymous_variant 0.25
ald 3087279 p.Gly154Trp missense_variant 0.13
ald 3087917 c.1098C>T synonymous_variant 0.17
fbiD 3339324 c.207G>C synonymous_variant 0.22
Rv3083 3448480 c.-24G>T upstream_gene_variant 0.2
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474813 p.Phe269Leu missense_variant 0.2
alr 3841251 p.Gly57Val missense_variant 0.2
rpoA 3877656 c.852T>C synonymous_variant 0.32
rpoA 3877667 p.Ser281Ala missense_variant 0.32
rpoA 3877668 c.840A>G synonymous_variant 0.32
rpoA 3877672 p.Thr279Ser missense_variant 0.32
rpoA 3877679 p.Ala277Ser missense_variant 0.33
rpoA 3877680 c.828G>C synonymous_variant 0.33
rpoA 3877686 c.822A>G synonymous_variant 0.32
rpoA 3877692 c.816G>C synonymous_variant 0.33
rpoA 3877695 c.813C>G synonymous_variant 0.35
rpoA 3877701 p.Val269Ile missense_variant 0.32
rpoA 3877743 c.765T>C synonymous_variant 0.23
rpoA 3877856 c.652T>C synonymous_variant 0.33
rpoA 3877863 c.645G>C synonymous_variant 0.42
rpoA 3877875 c.633T>G synonymous_variant 0.55
rpoA 3877884 p.Leu208Val missense_variant 0.55
rpoA 3877887 c.621G>C synonymous_variant 0.5
rpoA 3877899 p.Ser203Thr missense_variant 0.38
rpoA 3877905 c.603A>G synonymous_variant 0.38
rpoA 3877908 p.Asn200Pro missense_variant 0.4
rpoA 3877950 c.558C>G synonymous_variant 0.54
rpoA 3877962 c.546G>T synonymous_variant 0.4
rpoA 3877965 c.543C>G synonymous_variant 0.36
rpoA 3877971 p.Asp179Glu missense_variant 0.31
rpoA 3877974 c.534G>C synonymous_variant 0.29
rpoA 3877983 c.525C>G synonymous_variant 0.28
rpoA 3877989 c.519A>G synonymous_variant 0.33
rpoA 3877992 c.516C>G synonymous_variant 0.33
rpoA 3878001 c.507A>G synonymous_variant 0.36
rpoA 3878082 c.426T>C synonymous_variant 0.23
rpoA 3878103 c.405A>G synonymous_variant 0.33
rpoA 3878106 c.402G>C synonymous_variant 0.33
rpoA 3878118 c.390T>C synonymous_variant 0.28
rpoA 3878128 p.Thr127Trp missense_variant 0.25
rpoA 3878141 p.Met123Leu missense_variant 0.22
rpoA 3878142 p.Gly122Asp missense_variant 0.22
rpoA 3878145 c.363C>G synonymous_variant 0.22
rpoA 3878160 c.348C>G synonymous_variant 0.29
rpoA 3878163 c.345C>T synonymous_variant 0.3
rpoA 3878175 c.333G>C synonymous_variant 0.24
rpoA 3878184 p.Gly108Ala missense_variant 0.14
rpoA 3878187 c.321C>G synonymous_variant 0.13
rpoA 3878202 c.306G>C synonymous_variant 0.21
rpoA 3878205 c.303T>C synonymous_variant 0.21
rpoA 3878217 c.291A>G synonymous_variant 0.25
rpoA 3878232 c.276G>C synonymous_variant 0.3
rpoA 3878247 c.261G>C synonymous_variant 0.25
rpoA 3878259 c.249G>C synonymous_variant 0.26
rpoA 3878262 p.Ser82Glu missense_variant 0.26
rpoA 3878271 c.237T>C synonymous_variant 0.25
rpoA 3878295 c.213A>G synonymous_variant 0.19
rpoA 3878298 c.210A>G synonymous_variant 0.16
rpoA 3878301 c.207C>G synonymous_variant 0.17
rpoA 3878307 c.201C>G synonymous_variant 0.18
rpoA 3878310 c.198G>C synonymous_variant 0.19
rpoA 3878313 c.195G>C synonymous_variant 0.18
rpoA 3878322 c.186A>G synonymous_variant 0.14
rpoA 3878575 c.-68C>T upstream_gene_variant 1.0
clpC1 4038318 p.Pro796Leu missense_variant 1.0
clpC1 4038725 c.1980C>G synonymous_variant 0.24
clpC1 4038740 c.1965G>C synonymous_variant 0.35
clpC1 4038755 c.1950G>T synonymous_variant 0.46
clpC1 4038764 c.1941C>G synonymous_variant 0.48
clpC1 4038767 c.1938G>C synonymous_variant 0.46
clpC1 4038773 c.1932T>C synonymous_variant 0.46
clpC1 4038782 c.1923G>T synonymous_variant 0.48
clpC1 4038794 p.Ser637Thr missense_variant 0.55
clpC1 4038812 c.1893T>C synonymous_variant 0.57
clpC1 4038815 c.1890G>C synonymous_variant 0.57
clpC1 4038839 c.1866G>C synonymous_variant 0.5
clpC1 4038849 p.Phe619Tyr missense_variant 0.15
clpC1 4038855 p.Lys617Thr missense_variant 0.16
clpC1 4038860 c.1845G>C synonymous_variant 0.43
clpC1 4038863 c.1842G>C synonymous_variant 0.43
clpC1 4038867 p.Lys613Ala missense_variant 0.16
clpC1 4038875 c.1830C>G synonymous_variant 0.15
clpC1 4038878 c.1827A>G synonymous_variant 0.67
clpC1 4038881 c.1824C>T synonymous_variant 0.67
clpC1 4038885 p.Gly607Ala missense_variant 0.16
clpC1 4038905 c.1800A>C synonymous_variant 0.58
clpC1 4038908 c.1797C>G synonymous_variant 0.42
clpC1 4038911 c.1794G>T synonymous_variant 0.48
clpC1 4038914 c.1791G>C synonymous_variant 0.48
clpC1 4038917 c.1788C>T synonymous_variant 0.58
clpC1 4038923 c.1782A>G synonymous_variant 0.52
clpC1 4038932 c.1773G>C synonymous_variant 0.54
clpC1 4038939 p.Phe589Tyr missense_variant 0.54
clpC1 4038941 c.1764G>C synonymous_variant 0.54
clpC1 4038953 c.1752A>G synonymous_variant 0.58
clpC1 4038956 c.1749T>C synonymous_variant 0.58
clpC1 4038965 c.1740T>C synonymous_variant 0.67
clpC1 4038971 c.1734T>C synonymous_variant 0.61
clpC1 4038974 c.1731T>C synonymous_variant 0.6
clpC1 4038986 p.Asp573Glu missense_variant 0.63
clpC1 4038997 c.1708T>C synonymous_variant 0.66
clpC1 4039004 c.1701C>G synonymous_variant 0.63
clpC1 4039022 c.1683A>G synonymous_variant 0.66
clpC1 4039064 c.1641C>T synonymous_variant 0.7
clpC1 4039067 c.1638G>C synonymous_variant 0.68
clpC1 4039079 c.1626C>G synonymous_variant 0.64
clpC1 4039085 c.1620A>G synonymous_variant 0.58
clpC1 4039091 c.1614G>C synonymous_variant 0.6
clpC1 4039097 c.1608G>C synonymous_variant 0.56
clpC1 4039106 c.1599G>C synonymous_variant 0.56
clpC1 4039112 c.1593C>G synonymous_variant 0.5
clpC1 4039117 p.Lys530Gln missense_variant 0.44
clpC1 4039118 c.1587C>G synonymous_variant 0.44
clpC1 4039121 c.1584T>G synonymous_variant 0.48
clpC1 4039133 c.1572C>G synonymous_variant 0.59
clpC1 4039142 c.1563A>G synonymous_variant 0.48
clpC1 4039145 c.1560G>C synonymous_variant 0.48
clpC1 4039169 p.Glu512Asp missense_variant 0.36
clpC1 4039172 c.1533A>G synonymous_variant 0.36
clpC1 4039178 c.1527G>C synonymous_variant 0.37
clpC1 4039181 c.1522_1524delTTGinsCTC synonymous_variant 0.39
clpC1 4039187 c.1518G>T synonymous_variant 0.41
clpC1 4039190 c.1515C>G synonymous_variant 0.39
clpC1 4039193 c.1512C>G synonymous_variant 0.37
clpC1 4039199 p.Ala502Glu missense_variant 0.39
clpC1 4039430 c.1275T>C synonymous_variant 0.16
clpC1 4039442 c.1263A>G synonymous_variant 0.21
clpC1 4039448 c.1257A>G synonymous_variant 0.24
clpC1 4039454 c.1251A>T synonymous_variant 0.27
clpC1 4039463 c.1242C>G synonymous_variant 0.29
clpC1 4039466 c.1239T>C synonymous_variant 0.29
clpC1 4039469 c.1236T>C synonymous_variant 0.33
clpC1 4039472 c.1233G>C synonymous_variant 0.31
clpC1 4039478 c.1227G>C synonymous_variant 0.4
clpC1 4039481 c.1224T>G synonymous_variant 0.4
clpC1 4039484 c.1221T>C synonymous_variant 0.4
clpC1 4039487 c.1218G>A synonymous_variant 0.44
clpC1 4039517 c.1188C>G synonymous_variant 0.59
clpC1 4039524 p.Phe394Tyr missense_variant 0.59
clpC1 4039541 c.1164C>G synonymous_variant 0.7
clpC1 4039561 p.Ala382Ser missense_variant 0.66
clpC1 4039565 c.1140G>C synonymous_variant 0.66
clpC1 4039570 p.Met379Leu missense_variant 0.64
clpC1 4039571 c.1134G>A synonymous_variant 0.64
clpC1 4039576 p.Ala377Ser missense_variant 0.66
clpC1 4039577 c.1128T>C synonymous_variant 0.66
clpC1 4039610 c.1095G>C synonymous_variant 0.68
clpC1 4039622 c.1083C>T synonymous_variant 0.75
clpC1 4039649 p.Val352Leu missense_variant 0.75
clpC1 4039654 p.Thr351Ser missense_variant 0.78
clpC1 4039661 c.1044T>C synonymous_variant 0.77
clpC1 4039670 p.Val345Ile missense_variant 0.71
clpC1 4039724 c.981A>G synonymous_variant 0.45
clpC1 4039727 p.Asp326Glu missense_variant 0.42
clpC1 4039739 c.966C>G synonymous_variant 0.33
clpC1 4039742 c.963C>T synonymous_variant 0.29
clpC1 4039751 c.954A>G synonymous_variant 0.23
clpC1 4039757 c.948A>G synonymous_variant 0.14
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.14
clpC1 4039838 c.867G>C synonymous_variant 0.15
clpC1 4039874 p.Asn277Lys missense_variant 0.17
clpC1 4039889 c.816G>C synonymous_variant 0.27
clpC1 4039898 c.807C>G synonymous_variant 0.29
clpC1 4039901 c.804C>G synonymous_variant 0.29
clpC1 4039904 c.801A>G synonymous_variant 0.3
clpC1 4039907 c.798G>A synonymous_variant 0.29
clpC1 4039925 c.780C>G synonymous_variant 0.21
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.21
clpC1 4039931 c.774T>C synonymous_variant 0.22
clpC1 4039937 c.768G>C synonymous_variant 0.25
clpC1 4039946 c.759A>C synonymous_variant 0.26
clpC1 4039949 c.756G>C synonymous_variant 0.25
clpC1 4039952 c.753T>C synonymous_variant 0.32
clpC1 4039973 p.Asp244Glu missense_variant 0.49
clpC1 4040000 p.His235Lys missense_variant 0.56
clpC1 4040003 c.702G>C synonymous_variant 0.55
clpC1 4040010 p.Ala232Asn missense_variant 0.58
clpC1 4040024 c.681A>G synonymous_variant 0.67
clpC1 4040033 c.672G>C synonymous_variant 0.7
clpC1 4040036 c.669C>G synonymous_variant 0.68
clpC1 4040042 c.663C>T synonymous_variant 0.68
clpC1 4040048 c.657C>T synonymous_variant 0.71
clpC1 4040066 c.639G>C synonymous_variant 0.65
clpC1 4040087 c.618G>C synonymous_variant 0.38
clpC1 4040090 c.615T>G synonymous_variant 0.36
clpC1 4040093 c.612C>G synonymous_variant 0.33
clpC1 4040108 c.597G>C synonymous_variant 0.24
clpC1 4040117 c.588A>G synonymous_variant 0.29
clpC1 4040144 c.561G>C synonymous_variant 0.22
clpC1 4040273 c.432T>C synonymous_variant 0.17
clpC1 4040279 c.426C>G synonymous_variant 0.2
clpC1 4040282 c.423G>C synonymous_variant 0.2
clpC1 4040288 p.Ile139Leu missense_variant 0.2
clpC1 4040303 c.402G>C synonymous_variant 0.25
clpC1 4040306 c.399G>C synonymous_variant 0.24
clpC1 4040310 p.Thr132Asn missense_variant 0.22
clpC1 4040315 p.Glu130Asp missense_variant 0.24
clpC1 4040318 c.387C>G synonymous_variant 0.24
clpC1 4040324 c.381G>C synonymous_variant 0.3
clpC1 4040345 c.360C>G synonymous_variant 0.3
clpC1 4040348 c.357G>C synonymous_variant 0.3
clpC1 4040354 c.351A>G synonymous_variant 0.27
clpC1 4040363 c.342A>C synonymous_variant 0.23
clpC1 4040375 c.330G>C synonymous_variant 0.14
panD 4044213 c.69C>G synonymous_variant 0.12
embC 4240743 p.Asp294Val missense_variant 0.15
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245795 p.Ala855Thr missense_variant 0.13
ubiA 4269257 p.Tyr193His missense_variant 0.12
ethA 4326367 c.1107C>T synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408176 c.27T>C synonymous_variant 0.15