TB-Profiler result

Run: SRR7236330
Summary

Run ID: SRR7236330

Sample name:

Date: 2024-04-16T06:20:38.533383

Number of reads: 1000109

Percentage reads mapped: 42.68

Median coverage: 41.0

Strain: La1.8.1

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.8 M.bovis None 1.0
La1.8.1 M.bovis None 1.0
La1 M.bovis None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide pncA p.His57Asp Assoc w R
streptomycin rrs n.799C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fbiC c.2565_*56delCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN Assoc w R - Interim
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fbiC 1305494 c.2565_*56delCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN frameshift_variant&stop_lost&splice_region_variant 1.0 delamanid Assoc w R - Interim
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance Mutation from literature
pncA 2289073 p.His57Asp missense_variant 1.0 pyrazinamide Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 467 p.His156Arg missense_variant 1.0 isoniazid Not assoc w R
gyrB 5752 c.513G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6406 c.1167C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6446 p.Ala403Ser missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 8285 c.984C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9217 p.Asp639Ala missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
Rv0010c 13197 p.Thr121Ser missense_variant 1.0 isoniazid Not assoc w R
Rv0010c 13228 c.330delG frameshift_variant 1.0 isoniazid Uncertain significance
Rv0010c 13460 c.99T>C synonymous_variant 1.0 isoniazid Not assoc w R
fgd1 491742 c.960T>C synonymous_variant 1.0 clofazimine Not assoc w R
pretomanid
delamanid Not assoc w R - Interim
Rv0565c 657578 c.-108T>C upstream_gene_variant 1.0 ethionamide
rpoB 762167 c.2361T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762173 p.Glu789Asp missense_variant 0.18 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762194 c.2388G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762224 c.2418C>T synonymous_variant 0.16 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.12 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 762905 p.Asp1033Glu missense_variant 0.21 rifampicin
rpoC 762911 c.-459C>T upstream_gene_variant 0.25 rifampicin
rpoB 762920 c.3114C>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762926 c.3120C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 762932 c.-438G>T upstream_gene_variant 0.28 rifampicin
rpoC 762938 c.-432G>C upstream_gene_variant 0.41 rifampicin
rpoC 762944 c.-426C>T upstream_gene_variant 0.44 rifampicin
rpoC 762956 c.-414G>A upstream_gene_variant 0.49 rifampicin
rpoB 762962 c.3156C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762971 c.3165G>A synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>A upstream_gene_variant 0.53 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 0.54 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 763005 p.Cys1067Val missense_variant 0.54 rifampicin
rpoC 763013 c.-357C>A upstream_gene_variant 0.56 rifampicin
rpoC 763022 c.-348C>G upstream_gene_variant 0.55 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.45 rifampicin Not assoc w R
rpoC 763052 c.-318G>C upstream_gene_variant 0.56 rifampicin
rpoB 763053 c.3247T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 763074 p.Thr1090Val missense_variant 0.53 rifampicin
rpoC 763079 c.-291C>T upstream_gene_variant 0.53 rifampicin
rpoB 763088 c.3282C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763100 c.-270G>A upstream_gene_variant 0.5 rifampicin
rpoC 763109 c.-261C>G upstream_gene_variant 0.48 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 763124 c.-246C>T upstream_gene_variant 0.4 rifampicin
rpoB 763130 p.Glu1108Asp missense_variant 0.39 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 0.37 rifampicin
rpoC 763142 c.-228C>A upstream_gene_variant 0.36 rifampicin
rpoC 763148 c.-222G>C upstream_gene_variant 0.37 rifampicin
rpoC 763160 c.-210G>C upstream_gene_variant 0.3 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.24 rifampicin
rpoC 763178 c.-192G>C upstream_gene_variant 0.21 rifampicin
rpoC 763181 c.-189G>C upstream_gene_variant 0.2 rifampicin
rpoC 764485 c.1116G>C synonymous_variant 0.17 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>T synonymous_variant 0.34 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>T synonymous_variant 0.36 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>T synonymous_variant 0.36 rifampicin
rpoC 764536 c.1167G>C synonymous_variant 0.36 rifampicin
rpoC 764539 c.1170C>A synonymous_variant 0.36 rifampicin
rpoC 764548 c.1179G>A synonymous_variant 0.39 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764572 c.1203G>T synonymous_variant 0.42 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>T synonymous_variant 0.4 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.4 rifampicin
rpoC 764599 c.1230G>A synonymous_variant 0.39 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>C synonymous_variant 0.39 rifampicin
rpoC 764623 c.1254C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764635 c.1266C>G synonymous_variant 0.36 rifampicin
rpoC 764644 c.1275G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764647 c.1278C>T synonymous_variant 0.37 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764653 c.1284G>C synonymous_variant 0.4 rifampicin
rpoC 764656 c.1287C>G synonymous_variant 0.38 rifampicin
rpoC 764659 c.1290C>T synonymous_variant 0.38 rifampicin
rpoC 764660 c.1291_1293delGTGinsAC frameshift_variant&missense_variant 0.38 rifampicin
rpoC 764665 c.1296C>T synonymous_variant 0.37 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764677 c.1308C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764692 c.1323C>T synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 764731 c.1362G>A synonymous_variant 0.45 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764749 c.1380G>C synonymous_variant 0.36 rifampicin
rpoC 764755 p.Asp462Glu missense_variant 0.36 rifampicin
rpoC 764756 p.Leu463Lys missense_variant 0.36 rifampicin
rpoC 764760 p.Asn464Ser missense_variant 0.36 rifampicin
rpoC 764762 c.1393_1395delCATinsTC frameshift_variant&missense_variant 0.38 rifampicin
rpoC 764780 c.1411_1412delAGinsTC synonymous_variant 0.4 rifampicin
rpoC 764785 c.1416C>T synonymous_variant 0.39 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.41 rifampicin Not assoc w R
rpoC 764813 c.1444_1446delCAAinsGG frameshift_variant&missense_variant 0.4 rifampicin
rpoC 764824 c.1455T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 0.38 rifampicin
rpoC 764838 p.Val490Ala missense_variant 0.34 rifampicin
rpoC 764842 c.1473C>T synonymous_variant 0.34 rifampicin
rpoC 764843 p.Ala492Ser missense_variant 0.34 rifampicin
rpoC 764854 c.1485G>A synonymous_variant 0.35 rifampicin
rpoC 764858 p.Leu497Met missense_variant 0.35 rifampicin
rpoC 764863 c.1494G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764902 c.1533C>G synonymous_variant 0.34 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.35 rifampicin
rpoC 764914 p.Met515Ile missense_variant 0.34 rifampicin Uncertain significance
rpoC 764923 c.1554A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764941 c.1572G>T synonymous_variant 0.29 rifampicin
rpoC 764947 c.1578G>T synonymous_variant 0.25 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764952 p.Val528Ala missense_variant 0.23 rifampicin
rpoC 764959 c.1590G>A synonymous_variant 0.23 rifampicin
rpoC 764965 c.1596C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>A synonymous_variant 0.25 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 776100 p.Thr794Ile missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 moxifloxacin Not assoc w R
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
Rv1129c 1254582 c.-48A>G upstream_gene_variant 1.0 moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Not assoc w R
isoniazid Not assoc w R
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
Rv1258c 1406492 c.849C>T synonymous_variant 1.0 streptomycin
isoniazid
pyrazinamide
embR 1417554 c.-207C>G upstream_gene_variant 1.0 ethambutol
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.36 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.36 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471928 n.83T>G non_coding_transcript_exon_variant 0.35 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471930 n.85_89delGGAGAinsTTGCAGGG non_coding_transcript_exon_variant 0.36 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471978 n.133C>T non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471979 n.134T>C non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471981 n.136C>T non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472027 n.183_188delACGGGA non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472037 n.192A>T non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472039 n.194G>T non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472041 n.196C>A non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472045 n.200_201insAGAA non_coding_transcript_exon_variant 0.73 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472054 n.210_212delCGC non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472062 n.217G>T non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472067 n.222G>A non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472068 n.223T>C non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472070 n.225G>A non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>C non_coding_transcript_exon_variant 0.23 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.77 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.69 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.69 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472293 n.448C>A non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472298 n.453_466delGTCCGGGTTCTCTCinsCCACTTATGT non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472313 n.469_470delAT non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.69 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472330 n.485G>T non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.8 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>G non_coding_transcript_exon_variant 0.73 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.73 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472466 n.621C>T non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472467 n.622G>C non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.72 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472485 n.640delGinsTA non_coding_transcript_exon_variant 0.74 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.78 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472674 n.829T>A non_coding_transcript_exon_variant 0.78 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.77 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472680 n.836_837delCT non_coding_transcript_exon_variant 0.76 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472684 n.839G>A non_coding_transcript_exon_variant 0.75 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472685 n.840G>C non_coding_transcript_exon_variant 0.76 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472687 n.843_844insTT non_coding_transcript_exon_variant 0.75 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.74 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.69 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 0.65 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472840 n.995A>C non_coding_transcript_exon_variant 0.63 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472843 n.998_999insTCGG non_coding_transcript_exon_variant 0.66 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472846 n.1002_1005delGTCT non_coding_transcript_exon_variant 0.65 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472856 n.1012_1013delAG non_coding_transcript_exon_variant 0.66 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472861 n.1017_1018insCT non_coding_transcript_exon_variant 0.65 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472874 n.1029C>T non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.78 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.78 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.77 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473083 n.1238G>A non_coding_transcript_exon_variant 0.78 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473089 n.1244A>T non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.78 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473128 n.1283C>T non_coding_transcript_exon_variant 0.8 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin
amikacin Uncertain significance
rrs 1473132 n.1287T>C non_coding_transcript_exon_variant 0.81 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.63 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.64 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.64 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.62 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid
rrl 1474182 n.525C>A non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.529delA non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1474200 n.545delT non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717delTinsATTG non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1474384 n.727C>T non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1474487 n.830G>T non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474498 n.841G>A non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1474505 n.848C>T non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>C non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474517 n.860C>G non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474628 n.971C>T non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474658 n.1001A>T non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474662 n.1005C>T non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474664 n.1007G>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474666 n.1009T>G non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474667 n.1010G>C non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1474670 n.1013C>G non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474671 n.1014C>A non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1474675 n.1018C>T non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474678 n.1021G>T non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1474679 n.1022G>C non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474683 n.1026C>G non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1474684 n.1027T>C non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474688 n.1031G>A non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1474710 n.1053T>G non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474712 n.1055_1057delGTGinsAAGT non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474717 n.1060A>G non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1474721 n.1064G>A non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474798 n.1141C>A non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474825 n.1168G>A non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.49 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474921 n.1264C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475696 n.2039T>A non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1475699 n.2042delCinsAT non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1475703 n.2046A>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1475756 n.2101_2108delACCCGCAA non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1475769 n.2112delTinsCATTAATGTCC non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.84 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1476033 n.2376T>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1476040 n.2383C>T non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476080 n.2423T>A non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1476085 n.2428G>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1476091 n.2434_2435insC non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476100 n.2443A>C non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.86 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.86 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.86 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.87 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1476276 n.2619C>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.85 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1476524 n.2867_2868delCAinsT non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476544 n.2887T>A non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1476566 n.2909A>T non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>G non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476595 n.2938C>A non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476600 n.2943A>C non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1476602 n.2945G>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.22 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476624 n.2967T>A non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476625 n.2968C>T non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833649 c.108C>T synonymous_variant 0.43 pyrazinamide
rpsA 1833655 c.114C>T synonymous_variant 0.42 pyrazinamide
rpsA 1833668 p.Ile43Val missense_variant 0.43 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.4 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 0.4 pyrazinamide
rpsA 1833682 c.141C>T synonymous_variant 0.4 pyrazinamide
rpsA 1833684 p.Arg48Gln missense_variant 0.41 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 0.44 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.48 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 0.48 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.48 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.48 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.48 pyrazinamide
rpsA 1833739 c.198C>G synonymous_variant 0.46 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.49 pyrazinamide
rpsA 1833763 c.222C>A synonymous_variant 0.48 pyrazinamide
rpsA 1833771 p.Asn77Ser missense_variant 0.45 pyrazinamide
rpsA 1833782 p.Ser81Glu missense_variant 0.43 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.43 pyrazinamide
rpsA 1833797 p.Val86Ile missense_variant 0.43 pyrazinamide Uncertain significance
rpsA 1833802 p.Glu87Asp missense_variant 0.44 pyrazinamide
rpsA 1833805 c.264C>A synonymous_variant 0.43 pyrazinamide
rpsA 1833808 c.267G>T synonymous_variant 0.43 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.43 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.46 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.47 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.47 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.48 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.53 pyrazinamide
rpsA 1833862 c.321G>A synonymous_variant 0.51 pyrazinamide
rpsA 1833877 c.336C>A synonymous_variant 0.41 pyrazinamide
rpsA 1833883 c.342C>T synonymous_variant 0.36 pyrazinamide
rpsA 1833884 p.Thr115Ala missense_variant 0.36 pyrazinamide Uncertain significance
rpsA 1833892 c.351G>A synonymous_variant 0.38 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.37 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.36 pyrazinamide
rpsA 1833914 c.373_375delGCCinsCA frameshift_variant&missense_variant 0.36 pyrazinamide Uncertain significance
rpsA 1833921 p.Lys127Thr missense_variant 0.37 pyrazinamide
rpsA 1833925 c.384C>T synonymous_variant 0.36 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.36 pyrazinamide
rpsA 1833940 c.399C>T synonymous_variant 0.38 pyrazinamide
rpsA 1833952 c.411C>A synonymous_variant 0.32 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 0.33 pyrazinamide
rpsA 1833961 c.420C>G synonymous_variant 0.33 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.3 pyrazinamide
rpsA 1833973 c.432G>C synonymous_variant 0.3 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.29 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.27 pyrazinamide
rpsA 1833988 c.447C>T synonymous_variant 0.26 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 0.26 pyrazinamide
rpsA 1833994 c.453G>C synonymous_variant 0.26 pyrazinamide
rpsA 1833997 c.456G>C synonymous_variant 0.26 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.28 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.27 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.27 pyrazinamide
rpsA 1834015 c.474G>T synonymous_variant 0.27 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.26 pyrazinamide
rpsA 1834030 c.489C>A synonymous_variant 0.25 pyrazinamide
rpsA 1834040 p.Lys167Gln missense_variant 0.25 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 0.22 pyrazinamide
rpsA 1834076 p.Asn179His missense_variant 0.16 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.15 pyrazinamide
rpsA 1834432 c.891G>T synonymous_variant 0.19 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.27 pyrazinamide
rpsA 1834459 c.918G>A synonymous_variant 0.31 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.32 pyrazinamide
rpsA 1834474 c.933C>T synonymous_variant 0.35 pyrazinamide
rpsA 1834483 c.942G>A synonymous_variant 0.36 pyrazinamide
rpsA 1834489 c.948T>A synonymous_variant 0.39 pyrazinamide
rpsA 1834504 c.963G>T synonymous_variant 0.43 pyrazinamide
rpsA 1834540 c.999G>T synonymous_variant 0.44 pyrazinamide Not assoc w R - Interim
rpsA 1834543 c.1002C>A synonymous_variant 0.45 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.46 pyrazinamide
rpsA 1834552 c.1011G>T synonymous_variant 0.46 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 0.47 pyrazinamide
rpsA 1834556 p.Ala339Thr missense_variant 0.46 pyrazinamide Uncertain significance
rpsA 1834561 c.1020C>T synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
rpsA 1834564 c.1023C>T synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
rpsA 1834565 c.1024_1026delGACinsCG frameshift_variant&missense_variant 0.47 pyrazinamide Uncertain significance
rpsA 1834570 c.1029C>T synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
rpsA 1834573 c.1032G>C synonymous_variant 0.48 pyrazinamide
rpsA 1834600 c.1059G>C synonymous_variant 0.47 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.48 pyrazinamide
rpsA 1834612 c.1071G>T synonymous_variant 0.48 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 0.47 pyrazinamide
rpsA 1834624 c.1083G>C synonymous_variant 0.47 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.47 pyrazinamide
rpsA 1834636 c.1095C>T synonymous_variant 0.47 pyrazinamide
rpsA 1834637 c.1096_1098delAATinsGC frameshift_variant&missense_variant 0.47 pyrazinamide Uncertain significance
rpsA 1834654 c.1113G>A synonymous_variant 0.48 pyrazinamide
rpsA 1834666 c.1125G>A synonymous_variant 0.42 pyrazinamide
rpsA 1834667 c.1126_1128delGCGinsTC frameshift_variant&missense_variant 0.41 pyrazinamide Uncertain significance
rpsA 1834684 c.1143C>T synonymous_variant 0.43 pyrazinamide
rpsA 1834688 c.1147_1148delAGinsTC synonymous_variant 0.41 pyrazinamide
rpsA 1834696 c.1155C>T synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
rpsA 1834720 c.1179C>T synonymous_variant 0.26 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.23 pyrazinamide
rpsA 1834733 c.1192_1194delGCCinsCA frameshift_variant&missense_variant 0.2 pyrazinamide Uncertain significance
rpsA 1834738 c.1197A>G synonymous_variant 0.2 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.15 pyrazinamide
rpsA 1834859 p.Ala440Thr missense_variant 1.0 pyrazinamide Uncertain significance
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
bacA 2062922 p.Ile603Val missense_variant 1.0 streptomycin Not assoc w R
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
ndh 2102193 p.Arg284Trp missense_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2103173 c.-132delG upstream_gene_variant 1.0 ethionamide
delamanid
isoniazid
katG 2154687 c.1425C>T synonymous_variant 1.0 isoniazid
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Not assoc w R
katG 2155503 c.609C>T synonymous_variant 1.0 isoniazid Not assoc w R
katG 2156025 c.87C>A synonymous_variant 1.0 isoniazid Not assoc w R
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Not assoc w R
PPE35 2168011 p.Ser868Arg missense_variant 1.0 pyrazinamide Uncertain significance
PPE35 2168319 p.Thr765Ile missense_variant 1.0 pyrazinamide Uncertain significance
PPE35 2168814 c.1798dupA frameshift_variant 1.0 pyrazinamide Uncertain significance
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
kasA 2518132 c.18C>T synonymous_variant 1.0 isoniazid
eis 2715125 p.Thr70Ala missense_variant 1.0 amikacin Uncertain significance
kanamycin Uncertain significance
Rv2477c 2782927 c.1116A>G synonymous_variant 1.0 ethambutol Not assoc w R
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R
amikacin Not assoc w R - Interim
Rv2681 2997325 p.Ala196Val missense_variant 1.0 capreomycin Uncertain significance
ald 3086728 c.-92C>T upstream_gene_variant 1.0 cycloserine
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
ald 3087084 c.266delA frameshift_variant 1.0 cycloserine
Rv3083 3448783 p.Val94Ile missense_variant 1.0 ethionamide Uncertain significance
lpqB 3623372 c.1539G>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R
lpqB 3623730 p.Ser394Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3624350 c.561G>T synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R
lpqB 3624486 p.Asp142Gly missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3624593 c.318G>A synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R
lpqB 3624710 c.201G>A synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038744 p.Thr654Glu missense_variant 0.17 pyrazinamide
clpC1 4038755 c.1950G>A synonymous_variant 0.17 pyrazinamide
clpC1 4038764 c.1941C>G synonymous_variant 0.17 pyrazinamide
clpC1 4038767 c.1938G>T synonymous_variant 0.17 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.17 pyrazinamide
clpC1 4038773 p.Asp644Glu missense_variant 0.17 pyrazinamide
clpC1 4038776 c.1929G>A synonymous_variant 0.17 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.16 pyrazinamide
clpC1 4038782 c.1923G>T synonymous_variant 0.18 pyrazinamide
clpC1 4038793 c.1912C>T synonymous_variant 0.22 pyrazinamide
clpC1 4038795 p.Ser637Thr missense_variant 0.25 pyrazinamide
clpC1 4038811 p.Gln632Lys missense_variant 0.28 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.28 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.32 pyrazinamide
clpC1 4038851 c.1854G>A synonymous_variant 0.32 pyrazinamide
clpC1 4038860 c.1845G>T synonymous_variant 0.33 pyrazinamide
clpC1 4038863 c.1842G>T synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4038872 c.1833C>T synonymous_variant 0.35 pyrazinamide
clpC1 4038875 c.1830C>G synonymous_variant 0.36 pyrazinamide
clpC1 4038887 c.1818G>A synonymous_variant 0.37 pyrazinamide
clpC1 4038890 p.Glu605Asp missense_variant 0.36 pyrazinamide
clpC1 4038895 p.Tyr604His missense_variant 0.34 pyrazinamide
clpC1 4038899 c.1806C>G synonymous_variant 0.34 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.33 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.34 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.34 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.34 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.33 pyrazinamide
clpC1 4038926 c.1779G>C synonymous_variant 0.33 pyrazinamide
clpC1 4038929 c.1776G>C synonymous_variant 0.34 pyrazinamide
clpC1 4038932 c.1773G>C synonymous_variant 0.34 pyrazinamide
clpC1 4038935 c.1770C>G synonymous_variant 0.32 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.33 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.34 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.26 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4038977 c.1726_1728delGCGinsTC frameshift_variant&missense_variant 0.27 pyrazinamide
clpC1 4038983 c.1722C>T synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4038986 c.1719C>T synonymous_variant 0.28 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4039001 c.1702_1704delAACinsGG frameshift_variant&missense_variant 0.28 pyrazinamide
clpC1 4039007 c.1698G>T synonymous_variant 0.28 pyrazinamide
clpC1 4039021 c.1684C>T synonymous_variant 0.25 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.25 pyrazinamide
clpC1 4039034 c.1671C>G synonymous_variant 0.22 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.24 pyrazinamide
clpC1 4039871 p.Thr278Gln missense_variant 0.27 pyrazinamide
clpC1 4039886 c.819C>T synonymous_variant 0.24 pyrazinamide
glpK 4138377 p.Val460Ala missense_variant 1.0 ethambutol Not assoc w R
moxifloxacin Not assoc w R
streptomycin Not assoc w R
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
glpK 4138977 p.Gly260Ala missense_variant 1.0 ethambutol Not assoc w R
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Not assoc w R
isoniazid Uncertain significance
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embC 4242970 c.3108C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4244220 c.988C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4246551 p.Asn13Ser missense_variant 0.96 ethambutol Not assoc w R
embB 4246864 c.351C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4247646 p.Glu378Ala missense_variant 1.0 ethambutol Not assoc w R
aftB 4267858 p.Ile327Val missense_variant 1.0 ethambutol Not assoc w R
ubiA 4269351 c.483C>T synonymous_variant 1.0 ethambutol Not assoc w R
ubiA 4269387 p.Glu149Asp missense_variant 1.0 ethambutol Not assoc w R
ubiA 4269606 c.228T>C synonymous_variant 1.0 ethambutol Not assoc w R
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
gid 4407588 c.615A>G synonymous_variant 1.0 streptomycin Not assoc w R