TB-Profiler result

Run: ERR10796598
Summary

Run ID: ERR10796598

Sample name:

Date: 31-03-2023 11:12:16

Number of reads: 1513637

Percentage reads mapped: 99.63

Strain: lineage4.9

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.96
lineage4.9 Euro-American (H37Rv-like) T1 None 0.97
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 1.0 rifampicin
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.29 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.42 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.36 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7503 p.Arg68Cys missense_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491668 p.Lys296Glu missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 760038 p.Gly78Cys missense_variant 0.5
rpoB 761099 c.1293C>T synonymous_variant 0.67
rpoB 761102 c.1296A>G synonymous_variant 0.67
rpoB 761132 c.1326G>T synonymous_variant 1.0
rpoB 761150 c.1344A>T synonymous_variant 1.0
rpoB 761159 c.1353G>C synonymous_variant 1.0
rpoB 762194 c.2388G>C synonymous_variant 0.62
rpoB 762200 c.2394C>T synonymous_variant 0.7
rpoB 762218 c.2412T>C synonymous_variant 0.43
rpoB 762233 c.2427G>C synonymous_variant 0.75
rpoB 762234 p.Pro810Ser missense_variant 0.79
rpoB 762239 c.2433G>A synonymous_variant 0.43
rpoB 762245 c.2439G>C synonymous_variant 0.79
rpoB 762248 c.2442G>C synonymous_variant 0.29
rpoB 762254 c.2448T>C synonymous_variant 0.73
rpoB 762293 c.2487T>C synonymous_variant 0.33
rpoC 762839 c.-531G>A upstream_gene_variant 0.75
rpoB 762855 p.Val1017Ile missense_variant 0.86
rpoB 762858 p.Thr1018Ser missense_variant 0.86
rpoC 762863 c.-507T>G upstream_gene_variant 0.89
rpoB 762871 p.Met1022Thr missense_variant 0.67
rpoB 762878 p.Ile1024Met missense_variant 0.55
rpoB 762879 p.Met1025Leu missense_variant 0.73
rpoC 762887 c.-483G>C upstream_gene_variant 0.86
rpoC 762899 c.-471G>C upstream_gene_variant 0.56
rpoC 762926 c.-444C>G upstream_gene_variant 0.66
rpoC 762929 c.-441G>C upstream_gene_variant 0.74
rpoC 762938 c.-432G>C upstream_gene_variant 0.24
rpoC 762947 c.-423C>G upstream_gene_variant 0.67
rpoC 762971 c.-399G>C upstream_gene_variant 0.81
rpoC 762980 c.-390T>C upstream_gene_variant 0.53
rpoC 762989 c.-381G>C upstream_gene_variant 0.76
rpoC 762995 c.-375G>C upstream_gene_variant 0.71
rpoB 763005 p.Cys1067Val missense_variant 0.58
rpoB 763014 p.Met1070Leu missense_variant 0.78
rpoB 763017 p.Gln1071Glu missense_variant 0.78
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoB 763038 p.Thr1078Ala missense_variant 0.67
rpoC 763043 c.-327G>C upstream_gene_variant 0.8
rpoC 763053 c.-317T>C upstream_gene_variant 0.88
rpoC 763070 c.-300T>C upstream_gene_variant 0.83
rpoB 763077 p.Val1091Ser missense_variant 0.8
rpoC 763103 c.-267G>C upstream_gene_variant 0.75
rpoC 763115 c.-255T>C upstream_gene_variant 0.4
rpoB 763119 p.Asn1105Asp missense_variant 0.6
rpoC 763570 c.201G>C synonymous_variant 0.57
rpoC 763578 p.Phe70Tyr missense_variant 0.57
rpoC 763606 c.237C>T synonymous_variant 0.67
rpoC 763609 c.240C>G synonymous_variant 0.67
rpoC 763615 c.246G>C synonymous_variant 0.71
rpoC 763622 p.Ala85Ser missense_variant 0.83
rpoC 763633 c.264T>C synonymous_variant 0.67
rpoC 763636 c.267T>C synonymous_variant 0.5
rpoC 763642 c.273G>T synonymous_variant 1.0
rpoC 763647 p.Gly93Ala missense_variant 0.4
rpoC 763654 c.285C>T synonymous_variant 0.55
rpoC 763655 p.Glu96Asn missense_variant 0.3
rpoC 763666 c.297G>C synonymous_variant 0.73
rpoC 763699 c.330G>T synonymous_variant 0.91
rpoC 763708 c.339G>A synonymous_variant 0.91
rpoC 763714 c.345G>C synonymous_variant 0.91
rpoC 763717 c.348T>C synonymous_variant 0.91
rpoC 763718 p.Leu117Val missense_variant 0.91
rpoC 763726 c.357C>T synonymous_variant 0.91
rpoC 763732 c.363C>T synonymous_variant 0.91
rpoC 763747 c.378G>A synonymous_variant 0.9
rpoC 763751 p.Ile128Val missense_variant 0.89
rpoC 763772 p.Val135Met missense_variant 0.67
rpoC 764632 c.1263T>C synonymous_variant 1.0
rpoC 764647 c.1278C>T synonymous_variant 1.0
rpoC 764650 c.1281G>T synonymous_variant 1.0
rpoC 764656 c.1287C>T synonymous_variant 1.0
rpoC 764662 c.1293G>C synonymous_variant 1.0
rpoC 764677 c.1308C>G synonymous_variant 1.0
rpoC 764678 p.Lys437Gln missense_variant 1.0
rpoC 764706 p.Leu446Gln missense_variant 1.0
rpoC 764713 c.1344G>T synonymous_variant 1.0
rpoC 764731 c.1362G>C synonymous_variant 1.0
rpoC 764737 c.1368G>C synonymous_variant 1.0
rpoC 764746 c.1377G>C synonymous_variant 1.0
rpoC 766231 c.2862T>C synonymous_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 777637 p.Ile282Phe missense_variant 1.0
mmpL5 778318 p.Thr55Ala missense_variant 0.67
rpsL 781760 c.201T>C synonymous_variant 0.4
rpsL 781766 c.207C>T synonymous_variant 0.4
rpsL 781796 p.Met79Ile missense_variant 0.4
rpsL 781802 c.243G>C synonymous_variant 0.4
rpsL 781805 c.246G>T synonymous_variant 0.4
rpsL 781811 c.252C>T synonymous_variant 0.4
rpsL 781814 c.255C>T synonymous_variant 0.4
rpsL 781817 c.258G>T synonymous_variant 0.4
rpsL 781832 c.273T>C synonymous_variant 0.67
rpsL 781835 c.276T>C synonymous_variant 0.67
rpsL 781841 c.282C>T synonymous_variant 0.67
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0
embR 1416311 p.Ser346Leu missense_variant 0.5
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471851 n.6T>C non_coding_transcript_exon_variant 1.0
rrs 1471852 n.7T>G non_coding_transcript_exon_variant 0.57
rrs 1471853 n.8T>C non_coding_transcript_exon_variant 0.26
rrs 1471996 n.151C>T non_coding_transcript_exon_variant 1.0
rrs 1472063 n.218C>T non_coding_transcript_exon_variant 0.38
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.94
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.9
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.99
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.3
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.39
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.67
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.35
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.29
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.55
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.57
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.56
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.97
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.56
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.53
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.43
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.45
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.98
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.27
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.39
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.89
rrs 1472319 n.474C>G non_coding_transcript_exon_variant 0.5
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.6
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.91
rrs 1472330 n.485G>T non_coding_transcript_exon_variant 0.63
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.79
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.97
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.83
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.92
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.57
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.83
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.96
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 0.6
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.9
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 0.92
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.95
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.95
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.95
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.97
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 1.0
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.98
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.99
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.47
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.56
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.32
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.32
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.99
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.99
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.55
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.29
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.29
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.47
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.99
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.89
rrs 1472690 n.845C>T non_coding_transcript_exon_variant 0.54
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.83
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.44
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.78
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.26
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.38
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.59
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.36
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.35
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.92
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.69
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 1.0
rrs 1472840 n.995A>G non_coding_transcript_exon_variant 0.94
rrs 1472844 n.999C>T non_coding_transcript_exon_variant 0.83
rrs 1472845 n.1000G>T non_coding_transcript_exon_variant 0.83
rrs 1472846 n.1001C>G non_coding_transcript_exon_variant 1.0
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.83
rrs 1472863 n.1018T>C non_coding_transcript_exon_variant 0.67
rrs 1472866 n.1021C>T non_coding_transcript_exon_variant 1.0
rrs 1472873 n.1028C>T non_coding_transcript_exon_variant 0.78
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.98
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.3
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.58
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.28
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.97
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.89
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.98
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.99
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.33
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.3
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.98
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.53
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.51
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 1.0
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.97
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.98
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.98
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.4
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.99
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.94
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.99
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.76
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.99
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.54
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.96
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.45
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.37
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.97
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.97
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.44
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.47
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.53
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.98
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.98
rrs 1473270 n.1425G>A non_coding_transcript_exon_variant 0.44
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 1.0
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.5
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.99
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.99
rrs 1473305 n.1460G>T non_coding_transcript_exon_variant 0.44
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.99
rrl 1473384 n.-274A>G upstream_gene_variant 0.58
rrl 1473390 n.-268A>C upstream_gene_variant 0.29
rrl 1473392 n.-266C>A upstream_gene_variant 0.56
rrl 1473739 n.82G>A non_coding_transcript_exon_variant 0.67
rrl 1474124 n.467G>C non_coding_transcript_exon_variant 0.85
rrl 1474125 n.468C>G non_coding_transcript_exon_variant 0.79
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.88
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.94
rrl 1474141 n.484G>C non_coding_transcript_exon_variant 0.89
rrl 1474142 n.485C>G non_coding_transcript_exon_variant 0.95
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.97
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 0.94
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.95
rrl 1474171 n.514C>T non_coding_transcript_exon_variant 0.43
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.95
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.98
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.44
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.45
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.98
rrl 1474199 n.542G>A non_coding_transcript_exon_variant 0.9
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.93
rrl 1474201 n.545delT non_coding_transcript_exon_variant 0.99
rrl 1474201 n.545T>C non_coding_transcript_exon_variant 0.97
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.94
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.35
rrl 1474271 n.614A>G non_coding_transcript_exon_variant 0.65
rrl 1474272 n.615C>T non_coding_transcript_exon_variant 0.65
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.99
rrl 1474288 n.631C>T non_coding_transcript_exon_variant 0.57
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.29
rrl 1474317 n.660G>A non_coding_transcript_exon_variant 0.3
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.72
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.96
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.61
rrl 1474353 n.696A>T non_coding_transcript_exon_variant 0.72
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.67
rrl 1474355 n.698A>G non_coding_transcript_exon_variant 0.22
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.97
rrl 1474365 n.708G>C non_coding_transcript_exon_variant 0.22
rrl 1474383 n.726G>T non_coding_transcript_exon_variant 0.81
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.96
rrl 1474439 n.782A>G non_coding_transcript_exon_variant 0.67
rrl 1474444 n.787G>C non_coding_transcript_exon_variant 0.66
rrl 1474448 n.791T>C non_coding_transcript_exon_variant 0.23
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.65
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.9
rrl 1474483 n.826C>T non_coding_transcript_exon_variant 0.38
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 1.0
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.78
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.59
rrl 1474497 n.840G>A non_coding_transcript_exon_variant 0.43
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.27
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.29
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.39
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.37
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.78
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 1.0
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.49
rrl 1474528 n.871T>A non_coding_transcript_exon_variant 0.4
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.86
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.83
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.51
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.99
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.48
rrl 1474540 n.883T>C non_coding_transcript_exon_variant 0.73
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.78
rrl 1474541 n.884G>T non_coding_transcript_exon_variant 0.38
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.48
rrl 1474551 n.894G>A non_coding_transcript_exon_variant 0.37
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.31
rrl 1474634 n.977T>C non_coding_transcript_exon_variant 0.59
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 1.0
rrl 1474709 n.1052G>A non_coding_transcript_exon_variant 0.69
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.99
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.67
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 1.0
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.64
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.6
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.64
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.99
rrl 1474801 n.1144G>A non_coding_transcript_exon_variant 0.27
rrl 1474802 n.1145T>C non_coding_transcript_exon_variant 0.6
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.73
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.28
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.99
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 1.0
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 1.0
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.83
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.91
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.48
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.24
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.73
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.85
rrl 1474933 n.1276A>G non_coding_transcript_exon_variant 0.64
rrl 1474934 n.1277C>T non_coding_transcript_exon_variant 0.57
rrl 1474946 n.1289C>T non_coding_transcript_exon_variant 0.56
rrl 1474948 n.1291C>T non_coding_transcript_exon_variant 0.51
rrl 1475018 n.1361G>C non_coding_transcript_exon_variant 0.6
rrl 1475026 n.1369G>C non_coding_transcript_exon_variant 0.6
rrl 1475031 n.1374G>C non_coding_transcript_exon_variant 0.67
rrl 1475059 n.1403_1404insTA non_coding_transcript_exon_variant 0.75
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.75
rrl 1475065 n.1409_1411delCAA non_coding_transcript_exon_variant 0.75
rrl 1475080 n.1425_1426delCC non_coding_transcript_exon_variant 0.75
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.88
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.95
rrl 1475109 n.1452C>T non_coding_transcript_exon_variant 0.29
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 1.0
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.94
rrl 1475137 n.1480A>T non_coding_transcript_exon_variant 0.46
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 0.73
rrl 1475172 n.1515A>G non_coding_transcript_exon_variant 0.3
rrl 1475175 n.1518G>C non_coding_transcript_exon_variant 0.63
rrl 1475188 n.1531C>G non_coding_transcript_exon_variant 0.57
rrl 1475499 n.1842C>T non_coding_transcript_exon_variant 1.0
rrl 1475515 n.1858G>A non_coding_transcript_exon_variant 0.59
rrl 1475518 n.1861A>G non_coding_transcript_exon_variant 0.31
rrl 1475521 n.1864T>C non_coding_transcript_exon_variant 0.3
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0
rrl 1475529 n.1872A>G non_coding_transcript_exon_variant 0.31
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.59
rrl 1475532 n.1875A>T non_coding_transcript_exon_variant 0.34
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.86
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.69
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.79
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.97
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.97
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 1.0
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 1.0
rrl 1475655 n.1998T>G non_coding_transcript_exon_variant 1.0
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.36
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.99
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.86
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.87
rrl 1475686 n.2029C>G non_coding_transcript_exon_variant 0.63
rrl 1475696 n.2039T>C non_coding_transcript_exon_variant 0.61
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 1.0
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 0.61
rrl 1475715 n.2058G>C non_coding_transcript_exon_variant 0.59
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.32
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.99
rrl 1475751 n.2094C>T non_coding_transcript_exon_variant 0.98
rrl 1475752 n.2095C>T non_coding_transcript_exon_variant 0.29
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.33
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.53
rrl 1475766 n.2110G>T non_coding_transcript_exon_variant 0.84
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.29
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.71
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.29
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 1.0
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 1.0
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.64
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.59
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.4
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.98
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.98
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.48
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 1.0
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.86
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.97
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.69
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.95
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.92
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.98
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 1.0
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 0.29
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.66
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.86
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.75
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.78
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.62
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.49
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.46
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 1.0
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 1.0
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.46
rrl 1476040 n.2383C>T non_coding_transcript_exon_variant 1.0
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.46
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.54
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.46
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.54
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0
rrl 1476080 n.2423T>G non_coding_transcript_exon_variant 1.0
rrl 1476085 n.2428G>A non_coding_transcript_exon_variant 1.0
rrl 1476097 n.2440C>T non_coding_transcript_exon_variant 1.0
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 1.0
rrl 1476100 n.2443A>C non_coding_transcript_exon_variant 1.0
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 1.0
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 1.0
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 1.0
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 0.45
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.57
rrl 1476116 n.2459A>G non_coding_transcript_exon_variant 0.35
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 0.55
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.87
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.58
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.36
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 1.0
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 1.0
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.92
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.35
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.67
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.74
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.92
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.71
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.88
rrl 1476253 n.2596A>G non_coding_transcript_exon_variant 0.58
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.87
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.81
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.74
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.64
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.75
rrl 1476297 n.2640C>A non_coding_transcript_exon_variant 0.44
rrl 1476299 n.2642C>G non_coding_transcript_exon_variant 0.34
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.58
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.93
rrl 1476306 n.2649A>G non_coding_transcript_exon_variant 0.23
rrl 1476307 n.2650A>T non_coding_transcript_exon_variant 0.43
rrl 1476308 n.2651G>C non_coding_transcript_exon_variant 0.34
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.63
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.72
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.58
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.58
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.61
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.63
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.34
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.64
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.65
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.31
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.67
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.66
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.66
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.94
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.9
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.39
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.94
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.96
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.32
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.39
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.58
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.31
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.26
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.99
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.99
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.99
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.7
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 1.0
rrl 1476536 n.2881A>G non_coding_transcript_exon_variant 1.0
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.39
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.44
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.97
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.97
rrl 1476592 n.2935G>A non_coding_transcript_exon_variant 0.28
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 0.48
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.44
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.82
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 1.0
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.43
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.91
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.67
rrl 1476633 n.2976A>G non_coding_transcript_exon_variant 0.3
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.61
rrl 1476664 n.3007T>A non_coding_transcript_exon_variant 0.39
rrl 1476665 n.3008T>G non_coding_transcript_exon_variant 0.59
rrl 1476668 n.3011C>T non_coding_transcript_exon_variant 0.5
rrl 1476675 n.3018C>G non_coding_transcript_exon_variant 1.0
inhA 1674434 p.Val78Ala missense_variant 1.0
rpsA 1833661 c.120A>G synonymous_variant 0.75
rpsA 1833667 c.126C>T synonymous_variant 0.75
rpsA 1833668 p.Ile43Val missense_variant 0.75
rpsA 1833676 c.135A>G synonymous_variant 0.75
rpsA 1833679 c.138G>C synonymous_variant 0.75
rpsA 1833684 p.Arg48His missense_variant 0.75
rpsA 1833694 c.153G>C synonymous_variant 0.83
rpsA 1833721 c.180A>G synonymous_variant 0.5
rpsA 1833727 c.186G>C synonymous_variant 1.0
rpsA 1833732 p.Pro64Leu missense_variant 1.0
rpsA 1833734 p.Ala65Ser missense_variant 0.5
rpsA 1833739 c.198C>T synonymous_variant 0.5
rpsA 1833742 c.201A>G synonymous_variant 1.0
rpsA 1833770 p.Asn77Asp missense_variant 1.0
rpsA 1833776 p.Val79Ile missense_variant 0.67
rpsA 1833781 c.240T>C synonymous_variant 0.67
rpsA 1833790 c.249T>C synonymous_variant 0.67
rpsA 1833797 p.Val86Ile missense_variant 0.67
rpsA 1833808 c.267G>C synonymous_variant 0.67
rpsA 1833949 c.408T>C synonymous_variant 1.0
rpsA 1833955 c.414G>C synonymous_variant 1.0
rpsA 1833970 c.429G>C synonymous_variant 1.0
rpsA 1833985 c.444G>C synonymous_variant 0.5
rpsA 1833994 c.453G>C synonymous_variant 0.5
rpsA 1834000 c.459G>C synonymous_variant 0.5
rpsA 1834009 c.468C>T synonymous_variant 0.5
rpsA 1834012 c.471G>C synonymous_variant 0.5
rpsA 1834015 c.474G>C synonymous_variant 0.5
rpsA 1834021 c.480C>T synonymous_variant 0.5
rpsA 1834024 c.483G>C synonymous_variant 0.5
rpsA 1834034 p.Ile165Val missense_variant 0.5
rpsA 1834039 c.498C>T synonymous_variant 0.5
rpsA 1834040 p.Lys167Arg missense_variant 0.5
rpsA 1834046 p.Ile169Leu missense_variant 0.5
rpsA 1834093 c.552G>T synonymous_variant 1.0
rpsA 1834096 c.555G>T synonymous_variant 0.67
rpsA 1834102 c.561T>C synonymous_variant 1.0
rpsA 1834108 c.567C>T synonymous_variant 1.0
rpsA 1834140 p.Ser200Thr missense_variant 1.0
rpsA 1834189 c.648G>C synonymous_variant 1.0
rpsA 1834195 c.654G>C synonymous_variant 1.0
rpsA 1834228 c.687C>T synonymous_variant 0.42
rpsA 1834231 c.690T>C synonymous_variant 0.37
rpsA 1834234 c.693G>C synonymous_variant 1.0
rpsA 1834240 c.699T>C synonymous_variant 1.0
rpsA 1834246 c.705G>T synonymous_variant 0.42
rpsA 1834249 c.708T>C synonymous_variant 0.95
rpsA 1834261 c.720A>G synonymous_variant 1.0
rpsA 1834264 c.723G>C synonymous_variant 1.0
rpsA 1834294 c.753G>C synonymous_variant 1.0
rpsA 1834298 p.Gln253Glu missense_variant 0.95
rpsA 1834306 c.765T>C synonymous_variant 0.95
rpsA 1834307 p.Asp256Gln missense_variant 0.95
rpsA 1834312 c.771G>A synonymous_variant 0.95
rpsA 1834327 c.786G>T synonymous_variant 0.92
rpsA 1834345 c.804C>T synonymous_variant 0.67
rpsA 1834451 c.910_912delTTGinsCTC synonymous_variant 1.0
rpsA 1834468 c.927A>G synonymous_variant 1.0
rpsA 1834474 c.933C>T synonymous_variant 1.0
rpsA 1834486 c.945G>A synonymous_variant 1.0
rpsA 1834489 c.948T>C synonymous_variant 1.0
rpsA 1834504 c.963G>T synonymous_variant 0.67
ndh 2102608 p.Leu145Phe missense_variant 0.5
ndh 2102862 p.Gly61Arg missense_variant 0.67
ndh 2102982 p.Gly21Arg missense_variant 0.4
ndh 2103038 p.Ser2Asn missense_variant 0.67
katG 2155403 p.Gly237Ser missense_variant 1.0
PPE35 2169552 p.Pro354His missense_variant 1.0
pncA 2290220 c.-979G>A upstream_gene_variant 0.5
kasA 2518132 c.18C>T synonymous_variant 1.0
eis 2715444 c.-112T>C upstream_gene_variant 0.67
Rv2752c 3065522 p.Arg224Trp missense_variant 0.4
Rv2752c 3066356 c.-165G>A upstream_gene_variant 0.5
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087084 c.266delA frameshift_variant 1.0
ald 3087145 p.Asp109Gly missense_variant 0.5
fprA 3474172 p.Asp56Asn missense_variant 0.5
whiB7 3568430 p.Gly84Arg missense_variant 0.67
fbiB 3641713 p.Leu60Gln missense_variant 1.0
ddn 3987029 c.186C>T synonymous_variant 0.5
clpC1 4040449 p.Lys86Glu missense_variant 0.67
embC 4241843 p.Leu661Ile missense_variant 1.0
embA 4244379 p.Pro383Ser missense_variant 1.0
embA 4244690 c.1458G>A synonymous_variant 1.0
embB 4249296 c.2785_2786delTG frameshift_variant 1.0
ubiA 4269097 p.Ser246Tyr missense_variant 0.67
aftB 4269522 c.-686C>T upstream_gene_variant 1.0
aftB 4269594 c.-758A>T upstream_gene_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
aftB 4269693 c.-857C>T upstream_gene_variant 1.0
ethA 4326465 p.Ile337Val missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4408334 c.-132G>C upstream_gene_variant 0.5