TB-Profiler result

Run: ERR987707
Summary

Run ID: ERR987707

Sample name:

Date: 2025-02-11T09:52:14.322187

Number of reads: 1053665

Percentage reads mapped: 19.79

Median coverage: 22.0

Strain: lineage4.7

Spoligotype:

Drug-resistance: MDR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.7 Euro-American (mainly T) None 1.0
lineage4 Euro-American None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB p.Ser441Ala Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
p.His445Asp Assoc w R
isoniazid katG p.Ser315Thr Assoc w R High-level resistance
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
capreomycin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
kanamycin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpoB 761127 p.Ser441Ala missense_variant 0.44 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
rpoB 761139 p.His445Asp missense_variant 0.46 rifampicin Assoc w R
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.87 amikacin Uncertain significance Mutation from literature
capreomycin Uncertain significance Mutation from literature
kanamycin Uncertain significance Mutation from literature
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.84 amikacin Assoc w R
capreomycin Assoc w R
kanamycin Assoc w R
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid Assoc w R High-level resistance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
rpoB 760234 p.Ser143Thr missense_variant 0.28 rifampicin
rpoB 760244 c.438G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760263 p.Met153Leu missense_variant 0.32 rifampicin
rpoB 760266 p.Met154Gln missense_variant 0.32 rifampicin
rpoB 760274 p.Glu156Asp missense_variant 0.33 rifampicin Uncertain significance
rpoB 760298 c.492G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.5 rifampicin
rpoB 760997 c.1191G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761013 p.Val403Ile missense_variant 0.41 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761046 p.Ile414Val missense_variant 0.46 rifampicin
rpoB 761051 c.1245G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>A synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 761088 c.1282_1284delAGCinsTCG synonymous_variant 0.46 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.5 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.52 rifampicin
rpoB 761126 c.1320G>C synonymous_variant 0.44 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761159 c.1353G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761171 c.1365C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>G synonymous_variant 0.36 rifampicin
rpoB 761183 c.1377T>C synonymous_variant 0.38 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 761196 p.Leu464Val missense_variant 0.4 rifampicin
rpoB 761207 c.1401C>T synonymous_variant 0.44 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.53 rifampicin
rpoB 761219 c.1413G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761234 c.1428G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761243 c.1437G>C synonymous_variant 0.43 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>C synonymous_variant 0.38 rifampicin
rpoB 761258 c.1452G>A synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 761534 c.1728G>C synonymous_variant 0.63 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761562 p.Ala586Ser missense_variant 0.78 rifampicin
rpoB 761565 p.Met587Leu missense_variant 0.75 rifampicin
rpoB 761570 c.1764T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.77 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761633 c.1827G>C synonymous_variant 0.62 rifampicin
rpoB 762879 p.Met1025Leu missense_variant 0.77 rifampicin Uncertain significance
rpoB 762899 c.3093G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 762911 c.-459C>T upstream_gene_variant 0.89 rifampicin
rpoB 762917 c.3111C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 762926 c.-444C>G upstream_gene_variant 0.86 rifampicin
rpoB 762929 c.3123G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 762932 c.-438G>C upstream_gene_variant 0.81 rifampicin
rpoB 762959 c.3153G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 762971 c.-399G>C upstream_gene_variant 0.62 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 0.32 rifampicin
rpoB 763031 c.3225T>C synonymous_variant 0.39 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 763038 p.Thr1078Ala missense_variant 0.36 rifampicin
rpoC 763052 c.-318G>C upstream_gene_variant 0.47 rifampicin
rpoC 763053 c.-317_-315delTTGinsCTC upstream_gene_variant 0.47 rifampicin
rpoC 763058 c.-312C>G upstream_gene_variant 0.62 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 763075 p.Thr1090Ile missense_variant 0.71 rifampicin
rpoB 763077 p.Val1091Leu missense_variant 0.71 rifampicin
rpoC 763103 c.-267G>C upstream_gene_variant 0.72 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763124 c.-246C>T upstream_gene_variant 0.69 rifampicin
rpoB 763126 p.Pro1107Gln missense_variant 0.69 rifampicin
rpoC 763133 c.-237G>C upstream_gene_variant 0.7 rifampicin
rpoC 763136 c.-234C>G upstream_gene_variant 0.7 rifampicin
rpoC 763148 c.-222G>C upstream_gene_variant 0.62 rifampicin
rpoC 763486 c.117T>G synonymous_variant 0.4 rifampicin
rpoC 763492 c.123G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 763507 c.138G>C synonymous_variant 0.5 rifampicin
rpoC 763511 p.Cys48Gly missense_variant 0.53 rifampicin
rpoC 763517 p.Lys50Gln missense_variant 0.54 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 763531 c.162G>C synonymous_variant 0.58 rifampicin Not assoc w R
rpoC 763532 p.Thr55Ser missense_variant 0.58 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 763550 p.Tyr61Ala missense_variant 0.57 rifampicin
rpoC 763570 c.201G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 763589 p.Ile74Val missense_variant 0.73 rifampicin
rpoC 763615 c.246G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763619 p.Arg84Lys missense_variant 0.64 rifampicin
rpoC 763622 p.Ala85Ser missense_variant 0.64 rifampicin Uncertain significance
rpoC 763625 p.Lys86Ser missense_variant 0.62 rifampicin
rpoC 763630 c.261G>C synonymous_variant 0.62 rifampicin
rpoC 763642 c.273G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.72 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.7 rifampicin
rpoC 763727 p.Leu120Met missense_variant 0.75 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.74 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.7 rifampicin
rpoC 763751 p.Ile128Val missense_variant 0.65 rifampicin
rpoC 764316 p.Ala316Val missense_variant 0.38 rifampicin
rpoC 764320 c.951C>T synonymous_variant 0.38 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.56 rifampicin
rpoC 764353 c.984G>C synonymous_variant 0.58 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.57 rifampicin
rpoC 764387 c.1018T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764398 c.1029G>C synonymous_variant 0.41 rifampicin
rpoC 764404 c.1035C>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764593 c.1224C>T synonymous_variant 0.44 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 0.55 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>C synonymous_variant 0.64 rifampicin
rpoC 764626 c.1257C>A synonymous_variant 0.73 rifampicin
rpoC 764632 c.1263T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764635 c.1266C>G synonymous_variant 0.71 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764653 c.1284G>C synonymous_variant 0.77 rifampicin
rpoC 764660 p.Val431Ile missense_variant 0.76 rifampicin
rpoC 764668 c.1299C>A synonymous_variant 0.76 rifampicin
rpoC 764671 c.1302G>C synonymous_variant 0.75 rifampicin
rpoC 764683 c.1314G>C synonymous_variant 0.69 rifampicin
rpoC 764706 p.Leu446Gln missense_variant 0.67 rifampicin Uncertain significance
rpoC 764713 c.1344G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 775715 c.2766G>A synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
Rv1129c 1253847 p.Ala230Thr missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
rifampicin Uncertain significance
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.48 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.51 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.73 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.73 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.72 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.71 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.72 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.82 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.86 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.84 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.83 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.21 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.19 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.23 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472333 n.488G>A non_coding_transcript_exon_variant 0.36 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.42 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.46 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.56 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.58 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472389 n.544G>A non_coding_transcript_exon_variant 0.57 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.45 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.36 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.66 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.66 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.7 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472507 n.662C>T non_coding_transcript_exon_variant 0.77 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472571 n.726G>A non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472606 n.761C>G non_coding_transcript_exon_variant 0.87 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.84 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 0.8 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472645 n.800G>C non_coding_transcript_exon_variant 0.67 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.58 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>A non_coding_transcript_exon_variant 0.54 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472666 n.821G>T non_coding_transcript_exon_variant 0.47 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.22 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472694 n.849C>A non_coding_transcript_exon_variant 0.29 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.4 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>T non_coding_transcript_exon_variant 0.66 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.81 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.79 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.43 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.74 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.86 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.78 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111_1112delTCinsCT non_coding_transcript_exon_variant 0.86 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.91 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.9 kanamycin Not assoc w R
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472993 n.1148G>T non_coding_transcript_exon_variant 0.9 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.89 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.89 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473097 n.1252G>A non_coding_transcript_exon_variant 0.9 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.89 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.89 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.89 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473134 n.1289T>C non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473147 n.1302G>A non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.9 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473269 n.1424C>T non_coding_transcript_exon_variant 0.85 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.85 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.86 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.84 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.85 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.86 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.84 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473320 n.1475G>A non_coding_transcript_exon_variant 0.86 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 0.85 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473883 n.226A>G non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473890 n.233T>C non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473917 n.260G>T non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473934 n.277G>T non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1474166 n.509G>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474184 n.527C>A non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474265 n.608G>T non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474275 n.618T>A non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1474280 n.623C>T non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1474291 n.635_645delTTCCTCTCCGG non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1474305 n.648G>T non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474308 n.653_654delTG non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474317 n.660G>A non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474601 n.944C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474770 n.1113G>A non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.78 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.78 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474800 n.1143T>C non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474920 n.1263G>A non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474935 n.1278A>G non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475084 n.1427G>T non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475108 n.1451C>T non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1475111 n.1454G>A non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475119 n.1462C>T non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475508 n.1851A>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475536 n.1879C>A non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.37 capreomycin
linezolid Uncertain significance
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1475692 n.2035G>C non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475758 n.2101_2102delACinsG non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475768 n.2111_2112delGTinsC non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.88 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid Uncertain significance
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476024 n.2367T>G non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.93 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.93 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.87 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.92 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.88 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.84 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1476544 n.2887T>A non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1476566 n.2909A>T non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.77 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476586 n.2929C>T non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.74 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476613 n.2956G>A non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.68 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>T non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rpsA 1834040 p.Lys167Gln missense_variant 0.34 pyrazinamide
rpsA 1834061 p.Ile174Leu missense_variant 0.36 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.32 pyrazinamide
rpsA 1834090 c.549G>C synonymous_variant 0.21 pyrazinamide
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
clpC1 4039714 p.Tyr331His missense_variant 0.3 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.3 pyrazinamide
clpC1 4040048 c.657C>T synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
clpC1 4040063 c.642G>C synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4040069 c.636G>C synonymous_variant 0.25 pyrazinamide
clpC1 4040081 p.Thr208Ser missense_variant 0.19 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 0.19 pyrazinamide
clpC1 4040090 c.615T>G synonymous_variant 0.21 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
clpC1 4040096 c.609G>C synonymous_variant 0.21 pyrazinamide
clpC1 4040108 c.597G>C synonymous_variant 0.18 pyrazinamide
clpC1 4040117 c.588A>G synonymous_variant 0.21 pyrazinamide
clpC1 4040129 c.576C>G synonymous_variant 0.23 pyrazinamide
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4249732 c.3219C>G synonymous_variant 1.0 ethambutol Not assoc w R
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
gid 4407590 p.Ala205Thr missense_variant 1.0 streptomycin Uncertain significance