TB-Profiler result

Run: ERR987707
Summary

Run ID: ERR987707

Sample name:

Date: 02-04-2023 13:21:06

Number of reads: 1053665

Percentage reads mapped: 19.79

Strain: lineage4.7

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.44 rifampicin
rpoB 761139 p.His445Asp missense_variant 0.46 rifampicin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.87 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.84 kanamycin, capreomycin, aminoglycosides, amikacin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
katG 2155693 p.Ser140Asn missense_variant 0.18 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoB 760208 p.Ile134Met missense_variant 0.2
rpoB 760212 p.Asn136His missense_variant 0.19
rpoB 760215 p.Asn137Gln missense_variant 0.19
rpoB 760234 p.Ser143Thr missense_variant 0.28
rpoB 760244 c.438G>C synonymous_variant 0.28
rpoB 760253 c.447T>C synonymous_variant 0.29
rpoB 760263 p.Met153Leu missense_variant 0.32
rpoB 760266 p.Met154Gln missense_variant 0.32
rpoB 760274 p.Glu156Asp missense_variant 0.33
rpoB 760298 c.492G>C synonymous_variant 0.28
rpoB 760310 c.504G>C synonymous_variant 0.19
rpoB 760985 c.1179G>C synonymous_variant 0.23
rpoB 760991 c.1185G>C synonymous_variant 0.5
rpoB 760997 c.1191G>C synonymous_variant 0.45
rpoB 761006 c.1200C>G synonymous_variant 0.44
rpoB 761013 p.Val403Ile missense_variant 0.41
rpoB 761027 c.1221A>G synonymous_variant 0.44
rpoB 761036 c.1230G>C synonymous_variant 0.48
rpoB 761037 c.1231T>C synonymous_variant 0.48
rpoB 761046 p.Ile414Val missense_variant 0.46
rpoB 761051 c.1245G>C synonymous_variant 0.48
rpoB 761054 c.1248G>C synonymous_variant 0.5
rpoB 761057 c.1251G>C synonymous_variant 0.52
rpoB 761084 c.1278C>A synonymous_variant 0.58
rpoB 761088 c.1282_1284delAGCinsTCG synonymous_variant 0.46
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.5
rpoB 761102 c.1296A>G synonymous_variant 0.52
rpoB 761126 c.1320G>C synonymous_variant 0.44
rpoB 761132 c.1326G>C synonymous_variant 0.43
rpoB 761133 c.1327T>C synonymous_variant 0.43
rpoB 761150 c.1344A>C synonymous_variant 0.57
rpoB 761159 c.1353G>C synonymous_variant 0.49
rpoB 761165 c.1359G>C synonymous_variant 0.43
rpoB 761171 c.1365C>T synonymous_variant 0.37
rpoB 761180 c.1374A>G synonymous_variant 0.36
rpoB 761183 c.1377T>C synonymous_variant 0.38
rpoB 761195 c.1389G>C synonymous_variant 0.4
rpoB 761196 p.Leu464Val missense_variant 0.4
rpoB 761207 c.1401C>T synonymous_variant 0.44
rpoB 761213 c.1407G>C synonymous_variant 0.53
rpoB 761219 c.1413G>C synonymous_variant 0.53
rpoB 761234 c.1428G>C synonymous_variant 0.43
rpoB 761243 c.1437G>C synonymous_variant 0.43
rpoB 761249 c.1443A>G synonymous_variant 0.45
rpoB 761255 c.1449T>C synonymous_variant 0.38
rpoB 761258 c.1452G>A synonymous_variant 0.39
rpoB 761261 c.1455G>C synonymous_variant 0.39
rpoB 761264 c.1458C>G synonymous_variant 0.38
rpoB 761289 p.Ser495Ala missense_variant 0.25
rpoB 761292 p.Val496Ser missense_variant 0.15
rpoB 761296 p.Tyr497Phe missense_variant 0.18
rpoB 761303 c.1497G>C synonymous_variant 0.18
rpoB 761304 p.Val500Ile missense_variant 0.18
rpoB 761310 p.Pro502Ala missense_variant 0.16
rpoB 761318 c.1512G>T synonymous_variant 0.17
rpoB 761327 c.1521A>G synonymous_variant 0.2
rpoB 761518 p.Asp571Gly missense_variant 0.15
rpoB 761534 c.1728G>C synonymous_variant 0.63
rpoB 761537 c.1731C>G synonymous_variant 0.65
rpoB 761558 c.1752C>G synonymous_variant 0.77
rpoB 761562 p.Ala586Ser missense_variant 0.78
rpoB 761565 p.Met587Leu missense_variant 0.75
rpoB 761570 c.1764T>C synonymous_variant 0.75
rpoB 761573 c.1767C>G synonymous_variant 0.77
rpoB 761579 c.1773G>C synonymous_variant 0.77
rpoB 761600 c.1794T>C synonymous_variant 0.77
rpoB 761612 c.1806G>T synonymous_variant 0.78
rpoB 761615 c.1809A>G synonymous_variant 0.77
rpoB 761633 c.1827G>C synonymous_variant 0.62
rpoB 761642 c.1836G>C synonymous_variant 0.2
rpoC 762863 c.-507T>C upstream_gene_variant 0.17
rpoB 762879 p.Met1025Leu missense_variant 0.77
rpoC 762899 c.-471G>C upstream_gene_variant 0.85
rpoC 762911 c.-459C>T upstream_gene_variant 0.89
rpoC 762917 c.-453C>G upstream_gene_variant 0.89
rpoC 762920 c.-450C>T upstream_gene_variant 0.85
rpoC 762923 c.-447C>G upstream_gene_variant 0.86
rpoC 762926 c.-444C>G upstream_gene_variant 0.86
rpoC 762929 c.-441G>C upstream_gene_variant 0.83
rpoC 762932 c.-438G>C upstream_gene_variant 0.81
rpoC 762959 c.-411G>C upstream_gene_variant 0.74
rpoC 762971 c.-399G>C upstream_gene_variant 0.62
rpoC 762989 c.-381G>C upstream_gene_variant 0.32
rpoC 762995 c.-375G>T upstream_gene_variant 0.19
rpoC 763031 c.-339T>C upstream_gene_variant 0.39
rpoC 763034 c.-336C>G upstream_gene_variant 0.35
rpoB 763038 p.Thr1078Ala missense_variant 0.36
rpoC 763052 c.-318G>C upstream_gene_variant 0.47
rpoC 763053 c.-317_-315delTTGinsCTC upstream_gene_variant 0.47
rpoC 763058 c.-312C>G upstream_gene_variant 0.62
rpoC 763070 c.-300T>C upstream_gene_variant 0.7
rpoB 763075 p.Thr1090Ile missense_variant 0.71
rpoB 763077 p.Val1091Leu missense_variant 0.71
rpoC 763103 c.-267G>C upstream_gene_variant 0.72
rpoC 763115 c.-255T>C upstream_gene_variant 0.71
rpoC 763124 c.-246C>T upstream_gene_variant 0.69
rpoB 763126 p.Pro1107Gln missense_variant 0.69
rpoC 763133 c.-237G>C upstream_gene_variant 0.7
rpoC 763136 c.-234C>G upstream_gene_variant 0.7
rpoC 763148 c.-222G>C upstream_gene_variant 0.62
rpoC 763456 c.87A>G synonymous_variant 0.15
rpoC 763462 c.93G>C synonymous_variant 0.24
rpoC 763486 c.117T>G synonymous_variant 0.4
rpoC 763492 c.123G>C synonymous_variant 0.44
rpoC 763507 c.138G>C synonymous_variant 0.5
rpoC 763511 p.Cys48Gly missense_variant 0.53
rpoC 763517 p.Lys50Gln missense_variant 0.54
rpoC 763528 c.159G>A synonymous_variant 0.57
rpoC 763531 c.162G>C synonymous_variant 0.58
rpoC 763532 p.Thr55Ser missense_variant 0.58
rpoC 763546 c.177A>G synonymous_variant 0.6
rpoC 763550 p.Tyr61Ala missense_variant 0.57
rpoC 763570 c.201G>C synonymous_variant 0.57
rpoC 763589 p.Ile74Val missense_variant 0.73
rpoC 763615 c.246G>C synonymous_variant 0.67
rpoC 763619 p.Arg84Lys missense_variant 0.64
rpoC 763622 p.Ala85Ser missense_variant 0.64
rpoC 763625 p.Lys86Ser missense_variant 0.62
rpoC 763630 c.261G>C synonymous_variant 0.62
rpoC 763642 c.273G>C synonymous_variant 0.67
rpoC 763660 c.291T>C synonymous_variant 0.76
rpoC 763675 c.306C>G synonymous_variant 0.72
rpoC 763696 c.327T>C synonymous_variant 0.71
rpoC 763708 c.339G>C synonymous_variant 0.72
rpoC 763714 c.345G>C synonymous_variant 0.69
rpoC 763717 c.348T>C synonymous_variant 0.71
rpoC 763723 c.354G>C synonymous_variant 0.7
rpoC 763727 p.Leu120Met missense_variant 0.75
rpoC 763732 c.363C>G synonymous_variant 0.74
rpoC 763744 c.375G>C synonymous_variant 0.7
rpoC 763751 p.Ile128Val missense_variant 0.65
rpoC 763765 c.396T>C synonymous_variant 0.35
rpoC 764316 p.Ala316Val missense_variant 0.38
rpoC 764320 c.951C>T synonymous_variant 0.38
rpoC 764344 c.975C>T synonymous_variant 0.56
rpoC 764353 c.984G>C synonymous_variant 0.58
rpoC 764365 c.996C>T synonymous_variant 0.59
rpoC 764371 c.1002G>C synonymous_variant 0.59
rpoC 764380 c.1011G>C synonymous_variant 0.57
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.57
rpoC 764387 c.1018T>C synonymous_variant 0.57
rpoC 764398 c.1029G>C synonymous_variant 0.41
rpoC 764404 c.1035C>T synonymous_variant 0.36
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.36
rpoC 764428 c.1059G>C synonymous_variant 0.26
rpoC 764455 c.1086G>C synonymous_variant 0.14
rpoC 764458 c.1089G>C synonymous_variant 0.14
rpoC 764461 c.1092A>G synonymous_variant 0.22
rpoC 764485 c.1116G>C synonymous_variant 0.24
rpoC 764497 c.1128A>G synonymous_variant 0.26
rpoC 764498 p.Ser377Ala missense_variant 0.29
rpoC 764503 c.1134G>C synonymous_variant 0.26
rpoC 764509 c.1140G>A synonymous_variant 0.27
rpoC 764521 c.1152T>C synonymous_variant 0.2
rpoC 764530 c.1161C>T synonymous_variant 0.23
rpoC 764533 c.1164C>T synonymous_variant 0.23
rpoC 764536 c.1167G>C synonymous_variant 0.23
rpoC 764593 c.1224C>T synonymous_variant 0.44
rpoC 764602 c.1233C>T synonymous_variant 0.55
rpoC 764605 c.1236G>C synonymous_variant 0.57
rpoC 764611 c.1242G>C synonymous_variant 0.64
rpoC 764626 c.1257C>A synonymous_variant 0.73
rpoC 764632 c.1263T>C synonymous_variant 0.63
rpoC 764635 c.1266C>G synonymous_variant 0.71
rpoC 764650 c.1281G>T synonymous_variant 0.78
rpoC 764653 c.1284G>C synonymous_variant 0.77
rpoC 764660 p.Val431Ile missense_variant 0.76
rpoC 764668 c.1299C>A synonymous_variant 0.76
rpoC 764671 c.1302G>C synonymous_variant 0.75
rpoC 764683 c.1314G>C synonymous_variant 0.69
rpoC 764706 p.Leu446Gln missense_variant 0.67
rpoC 764713 c.1344G>C synonymous_variant 0.63
rpoC 764716 c.1347G>C synonymous_variant 0.62
rpoC 764740 p.Met457Ile missense_variant 0.21
rpoC 764746 c.1377G>C synonymous_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775715 c.2766G>A synonymous_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471878 n.33C>T non_coding_transcript_exon_variant 0.14
rrs 1472067 n.222G>C non_coding_transcript_exon_variant 0.24
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.48
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.51
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.73
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.73
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.72
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.71
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.72
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.82
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.86
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.88
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.87
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.84
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.83
rrs 1472284 n.439C>T non_coding_transcript_exon_variant 0.27
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.21
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.19
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.23
rrs 1472333 n.488G>A non_coding_transcript_exon_variant 0.36
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.42
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.46
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.56
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.58
rrs 1472389 n.544G>A non_coding_transcript_exon_variant 0.57
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.45
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.36
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.12
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.66
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.66
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.7
rrs 1472507 n.662C>T non_coding_transcript_exon_variant 0.77
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.9
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.87
rrs 1472571 n.726G>A non_coding_transcript_exon_variant 0.87
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.88
rrs 1472606 n.761C>G non_coding_transcript_exon_variant 0.87
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.84
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 0.8
rrs 1472645 n.800G>C non_coding_transcript_exon_variant 0.67
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.58
rrs 1472660 n.815T>A non_coding_transcript_exon_variant 0.54
rrs 1472666 n.821G>T non_coding_transcript_exon_variant 0.47
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.22
rrs 1472674 n.829T>A non_coding_transcript_exon_variant 0.14
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.14
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.14
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.14
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.16
rrs 1472686 n.841G>T non_coding_transcript_exon_variant 0.14
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.19
rrs 1472694 n.849C>A non_coding_transcript_exon_variant 0.29
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.4
rrs 1472714 n.869A>T non_coding_transcript_exon_variant 0.66
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.81
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.79
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.43
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.42
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.43
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 0.2
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.74
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.86
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.78
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.91
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.9
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.9
rrs 1472993 n.1148G>T non_coding_transcript_exon_variant 0.9
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.89
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.9
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.9
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.89
rrs 1473097 n.1252G>A non_coding_transcript_exon_variant 0.9
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.9
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.9
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.89
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.89
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.89
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.9
rrs 1473134 n.1289T>C non_coding_transcript_exon_variant 0.92
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.9
rrs 1473147 n.1302G>A non_coding_transcript_exon_variant 0.9
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.9
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.91
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.88
rrs 1473269 n.1424C>T non_coding_transcript_exon_variant 0.85
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.85
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.86
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.84
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.85
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.86
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.84
rrs 1473320 n.1475G>A non_coding_transcript_exon_variant 0.86
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 0.85
rrl 1473828 n.173_174delTG non_coding_transcript_exon_variant 0.32
rrl 1473834 n.178_179insTAG non_coding_transcript_exon_variant 0.32
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.67
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 0.66
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.69
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.69
rrl 1473883 n.226A>G non_coding_transcript_exon_variant 0.7
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 0.7
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.7
rrl 1473890 n.233T>C non_coding_transcript_exon_variant 0.7
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.73
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.72
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.71
rrl 1473917 n.260G>T non_coding_transcript_exon_variant 0.65
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.64
rrl 1473934 n.277G>T non_coding_transcript_exon_variant 0.29
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 0.22
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.63
rrl 1474166 n.509G>A non_coding_transcript_exon_variant 0.62
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.81
rrl 1474184 n.527C>A non_coding_transcript_exon_variant 0.81
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.83
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.83
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.85
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.83
rrl 1474265 n.608G>T non_coding_transcript_exon_variant 0.74
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.73
rrl 1474275 n.618T>A non_coding_transcript_exon_variant 0.69
rrl 1474280 n.623C>T non_coding_transcript_exon_variant 0.68
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.66
rrl 1474291 n.635_645delTTCCTCTCCGG non_coding_transcript_exon_variant 0.42
rrl 1474305 n.648G>T non_coding_transcript_exon_variant 0.39
rrl 1474308 n.653_654delTG non_coding_transcript_exon_variant 0.39
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.5
rrl 1474317 n.660G>A non_coding_transcript_exon_variant 0.49
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.51
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.47
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.47
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.49
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.46
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.46
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.5
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 0.39
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.54
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.87
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.92
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.93
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.93
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.94
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.95
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.95
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.95
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.93
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.92
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.92
rrl 1474601 n.944C>T non_coding_transcript_exon_variant 0.92
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.89
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.89
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.89
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.89
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.89
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.83
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.69
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.69
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.69
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.69
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.69
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.8
rrl 1474770 n.1113G>A non_coding_transcript_exon_variant 0.82
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.78
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.78
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.78
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.78
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 0.85
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.87
rrl 1474800 n.1143T>C non_coding_transcript_exon_variant 0.88
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.92
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.89
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.89
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.89
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.89
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.67
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.66
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.64
rrl 1474920 n.1263G>A non_coding_transcript_exon_variant 0.64
rrl 1474935 n.1278A>G non_coding_transcript_exon_variant 0.46
rrl 1474938 n.1281G>A non_coding_transcript_exon_variant 0.26
rrl 1475084 n.1427G>T non_coding_transcript_exon_variant 0.36
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.56
rrl 1475108 n.1451C>T non_coding_transcript_exon_variant 0.58
rrl 1475111 n.1454G>A non_coding_transcript_exon_variant 0.57
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.59
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.58
rrl 1475119 n.1462C>T non_coding_transcript_exon_variant 0.61
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.61
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.61
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.62
rrl 1475508 n.1851A>T non_coding_transcript_exon_variant 0.72
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.69
rrl 1475536 n.1879C>A non_coding_transcript_exon_variant 0.72
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.73
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.73
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.72
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.72
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.72
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.72
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.37
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.26
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.26
rrl 1475692 n.2035G>C non_coding_transcript_exon_variant 0.63
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.92
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.92
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.91
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.88
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.88
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.88
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.89
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.91
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.9
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.9
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.89
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.88
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.88
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.88
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.87
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.87
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.87
rrl 1476024 n.2367T>G non_coding_transcript_exon_variant 0.73
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.59
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.49
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 0.5
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.5
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.5
rrl 1476045 n.2388G>A non_coding_transcript_exon_variant 0.5
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.49
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.46
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 0.49
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.19
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.17
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.66
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.82
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.89
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.93
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.93
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.89
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.88
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.87
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.86
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.87
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.83
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.78
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.78
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.77
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.77
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.77
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.76
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.79
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.81
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.86
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.88
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.9
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.92
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.88
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.84
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.76
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.7
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.67
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.67
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.68
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.7
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.69
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.7
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.7
rrl 1476544 n.2887T>A non_coding_transcript_exon_variant 0.73
rrl 1476566 n.2909A>T non_coding_transcript_exon_variant 0.84
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.84
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.77
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.77
rrl 1476586 n.2929C>T non_coding_transcript_exon_variant 0.77
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.74
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.72
rrl 1476613 n.2956G>A non_coding_transcript_exon_variant 0.68
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.68
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.68
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.66
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.64
rrl 1476630 n.2973A>T non_coding_transcript_exon_variant 0.64
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.15
rpsA 1833721 c.180A>G synonymous_variant 0.12
rpsA 1834012 c.471G>C synonymous_variant 0.14
rpsA 1834024 c.483G>C synonymous_variant 0.15
rpsA 1834025 p.Gln162Thr missense_variant 0.19
rpsA 1834030 c.489C>G synonymous_variant 0.29
rpsA 1834034 p.Ile165Leu missense_variant 0.32
rpsA 1834040 p.Lys167Gln missense_variant 0.34
rpsA 1834061 p.Ile174Leu missense_variant 0.36
rpsA 1834069 c.528G>C synonymous_variant 0.32
rpsA 1834090 c.549G>C synonymous_variant 0.21
rpsA 1834096 c.555G>C synonymous_variant 0.17
rpsA 1834099 c.558C>G synonymous_variant 0.17
rpsA 1834102 c.561T>C synonymous_variant 0.19
rpsA 1834109 p.Trp190Leu missense_variant 0.21
rpsA 1834114 c.573G>C synonymous_variant 0.21
rpsA 1834123 c.582C>G synonymous_variant 0.25
rpsA 1834129 c.588C>G synonymous_variant 0.14
rpsA 1834423 c.882G>T synonymous_variant 0.18
rpsA 1834431 p.Val297Ala missense_variant 0.17
rpsA 1834451 c.910_912delTTGinsCTC synonymous_variant 0.16
rpsA 1834468 c.927A>G synonymous_variant 0.21
rpsA 1834480 c.939C>G synonymous_variant 0.22
rpsA 1834482 p.Glu314Ala missense_variant 0.22
rpsA 1834486 p.Glu315Asp missense_variant 0.2
rpsA 1834489 c.948T>C synonymous_variant 0.2
rpsA 1834501 c.960G>C synonymous_variant 0.29
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155659 c.453C>G synonymous_variant 0.21
katG 2155662 c.450G>C synonymous_variant 0.21
katG 2155674 c.438G>T synonymous_variant 0.19
katG 2155680 c.432G>C synonymous_variant 0.2
katG 2155689 c.421_423delTTGinsCTC synonymous_variant 0.17
katG 2155696 p.Ala139Val missense_variant 0.17
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289482 c.-241C>A upstream_gene_variant 0.15
pncA 2290037 c.-796G>T upstream_gene_variant 0.12
kasA 2518348 c.234A>T synonymous_variant 0.14
Rv3083 3448982 p.Gly160Ala missense_variant 0.12
clpC1 4038860 c.1845G>T synonymous_variant 0.17
clpC1 4038863 c.1842G>A synonymous_variant 0.19
clpC1 4039691 c.1014G>C synonymous_variant 0.23
clpC1 4039694 c.1011G>C synonymous_variant 0.23
clpC1 4039700 c.1005C>T synonymous_variant 0.22
clpC1 4039711 p.Ile332Phe missense_variant 0.27
clpC1 4039714 p.Tyr331His missense_variant 0.3
clpC1 4039742 c.963C>T synonymous_variant 0.3
clpC1 4039748 c.957G>C synonymous_variant 0.25
clpC1 4039751 c.954A>G synonymous_variant 0.23
clpC1 4039754 c.951G>C synonymous_variant 0.23
clpC1 4039757 c.948A>G synonymous_variant 0.21
clpC1 4039766 c.939T>C synonymous_variant 0.17
clpC1 4040048 c.657C>T synonymous_variant 0.19
clpC1 4040063 c.642G>C synonymous_variant 0.26
clpC1 4040069 c.636G>C synonymous_variant 0.25
clpC1 4040081 p.Thr208Ser missense_variant 0.19
clpC1 4040087 c.618G>C synonymous_variant 0.19
clpC1 4040090 c.615T>G synonymous_variant 0.21
clpC1 4040093 c.612C>G synonymous_variant 0.2
clpC1 4040096 c.609G>C synonymous_variant 0.21
clpC1 4040108 c.597G>C synonymous_variant 0.18
clpC1 4040117 c.588A>G synonymous_variant 0.21
clpC1 4040129 c.576C>G synonymous_variant 0.23
clpC1 4040333 c.372G>C synonymous_variant 0.12
clpC1 4040348 c.357G>C synonymous_variant 0.22
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249732 c.3219C>G synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407590 p.Ala205Thr missense_variant 1.0