TB-Profiler result

Run: SRR26937071

Summary

Run ID: SRR26937071

Sample name:

Date: 06-02-2024 04:05:08

Number of reads: 2399182

Percentage reads mapped: 72.53

Strain: lineage2.2.1;La3

Drug-resistance: MDR-TB


Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Rifampicin R rpoB p.Ser450Leu (0.74)
Isoniazid R katG p.Ser315Thr (0.97)
Ethambutol R embA c.-16C>T (1.00), embB p.His312Arg (0.36), embB p.Leu359Ile (0.54), embB p.Asp1024Asn (0.74)
Pyrazinamide R pncA p.Trp68Gly (1.00)
Streptomycin R rpsL p.Lys43Arg (0.41), rrs n.462C>T (0.59)
Fluoroquinolones
Moxifloxacin
Ofloxacin
Levofloxacin
Ciprofloxacin
Aminoglycosides
Amikacin
Capreomycin
Kanamycin
Cycloserine
Ethionamide
Clofazimine
Para-aminosalicylic_acid
Delamanid
Bedaquiline
Linezolid
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
La3 M.orygis None None 0.12
lineage2 East-Asian Beijing RD105 0.97
La1.2.BCG M.bovis BCG None 0.33
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 0.96
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 0.74 rifampicin
rpsL 781687 p.Lys43Arg missense_variant 0.41 streptomycin
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.59 streptomycin
katG 2155168 p.Ser315Thr missense_variant 0.97 isoniazid
pncA 2289040 p.Trp68Gly missense_variant 1.0 pyrazinamide
embA 4243217 c.-16C>T upstream_gene_variant 1.0 ethambutol
embB 4247448 p.His312Arg missense_variant 0.36 ethambutol
embB 4247588 p.Leu359Ile missense_variant 0.54 ethambutol
embB 4249583 p.Asp1024Asn missense_variant 0.74 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6745 c.-557T>G upstream_gene_variant 0.19
gyrA 6751 c.-551G>C upstream_gene_variant 0.19
gyrA 6760 c.-542G>C upstream_gene_variant 0.21
gyrA 6763 c.-539G>C upstream_gene_variant 0.19
gyrA 6775 c.-527G>C upstream_gene_variant 0.2
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8189 c.888G>C synonymous_variant 0.2
gyrA 8198 c.897T>C synonymous_variant 0.19
gyrA 8207 c.906T>C synonymous_variant 0.24
gyrA 8219 c.918T>C synonymous_variant 0.23
gyrA 8225 c.924T>C synonymous_variant 0.27
gyrA 8234 c.933T>C synonymous_variant 0.26
gyrA 8237 c.936A>G synonymous_variant 0.26
gyrA 8247 p.Ile316Val missense_variant 0.25
gyrA 8264 c.963T>C synonymous_variant 0.21
gyrA 8270 c.969G>C synonymous_variant 0.2
gyrA 8288 c.987T>C synonymous_variant 0.19
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491601 c.819T>C synonymous_variant 0.19
fgd1 491610 c.828A>G synonymous_variant 0.22
fgd1 491616 c.834A>G synonymous_variant 0.23
fgd1 491620 p.Ile280Val missense_variant 0.23
fgd1 491643 c.861G>A synonymous_variant 0.22
fgd1 491646 c.864G>C synonymous_variant 0.22
fgd1 491649 c.867C>T synonymous_variant 0.22
fgd1 491658 c.876A>G synonymous_variant 0.2
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575907 p.Ala187Val missense_variant 1.0
ccsA 620340 c.450C>G synonymous_variant 0.27
ccsA 620346 c.456C>A synonymous_variant 0.3
ccsA 620362 p.Ala158Thr missense_variant 0.25
ccsA 620367 c.477T>C synonymous_variant 0.26
ccsA 620373 c.483C>G synonymous_variant 0.22
ccsA 620376 c.486G>C synonymous_variant 0.26
ccsA 620385 c.495G>C synonymous_variant 0.24
ccsA 620388 c.498A>G synonymous_variant 0.23
ccsA 620389 c.499C>T synonymous_variant 0.23
ccsA 620424 c.534G>C synonymous_variant 0.2
ccsA 620436 c.546T>A synonymous_variant 0.2
ccsA 620439 c.549T>C synonymous_variant 0.2
ccsA 620625 p.Ile245Met missense_variant 1.0
rpoB 760091 c.285G>C synonymous_variant 0.22
rpoB 760101 c.295T>C synonymous_variant 0.24
rpoB 760112 c.306T>C synonymous_variant 0.27
rpoB 760118 c.312T>G synonymous_variant 0.28
rpoB 760121 c.315T>C synonymous_variant 0.27
rpoB 760130 p.Asp108Glu missense_variant 0.26
rpoB 760139 c.333A>G synonymous_variant 0.28
rpoB 760142 c.336C>G synonymous_variant 0.28
rpoB 760181 c.375T>C synonymous_variant 0.32
rpoB 760184 c.378A>G synonymous_variant 0.31
rpoB 760196 c.390C>G synonymous_variant 0.3
rpoB 760223 c.417T>C synonymous_variant 0.36
rpoB 760235 c.429T>C synonymous_variant 0.37
rpoB 760283 c.477G>C synonymous_variant 0.48
rpoB 760298 c.492G>C synonymous_variant 0.47
rpoB 760307 c.501T>C synonymous_variant 0.45
rpoB 760310 c.504G>C synonymous_variant 0.47
rpoB 760328 c.522G>C synonymous_variant 0.5
rpoB 760331 c.525G>C synonymous_variant 0.51
rpoB 760340 c.534G>T synonymous_variant 0.53
rpoB 760361 c.555T>C synonymous_variant 0.51
rpoB 760370 c.564C>G synonymous_variant 0.49
rpoB 760376 p.Asp190Glu missense_variant 0.5
rpoB 760380 p.Thr192Leu missense_variant 0.48
rpoB 760406 c.600G>C synonymous_variant 0.46
rpoB 760412 c.606C>G synonymous_variant 0.42
rpoB 760424 c.618C>G synonymous_variant 0.39
rpoB 760430 c.624T>C synonymous_variant 0.39
rpoB 760475 c.669A>G synonymous_variant 0.27
rpoB 760481 c.675G>C synonymous_variant 0.22
rpoB 760484 c.678A>G synonymous_variant 0.2
rpoB 760655 c.849A>G synonymous_variant 0.33
rpoB 760661 c.855A>C synonymous_variant 0.35
rpoB 760670 c.864G>C synonymous_variant 0.36
rpoB 760674 c.868T>C synonymous_variant 0.36
rpoB 760679 c.873A>G synonymous_variant 0.36
rpoB 760683 c.877T>C synonymous_variant 0.37
rpoB 760715 c.909C>G synonymous_variant 0.39
rpoB 760718 c.912C>T synonymous_variant 0.39
rpoB 760724 c.918T>C synonymous_variant 0.37
rpoB 760730 c.924T>C synonymous_variant 0.35
rpoB 760751 c.945G>C synonymous_variant 0.32
rpoB 760757 c.951T>C synonymous_variant 0.3
rpoB 760759 p.Val318Ala missense_variant 0.27
rpoB 760769 c.963C>G synonymous_variant 0.26
rpoB 760775 c.969G>C synonymous_variant 0.28
rpoB 760776 c.970_972delTCGinsAGC synonymous_variant 0.28
rpoB 760793 c.987A>G synonymous_variant 0.26
rpoB 760805 c.999G>C synonymous_variant 0.25
rpoB 760817 c.1011A>G synonymous_variant 0.19
rpoB 760886 c.1080A>G synonymous_variant 0.28
rpoB 760925 c.1119T>C synonymous_variant 0.41
rpoB 760928 c.1122G>C synonymous_variant 0.42
rpoB 760934 c.1128C>T synonymous_variant 0.46
rpoB 760946 c.1140A>G synonymous_variant 0.46
rpoB 760949 c.1143C>T synonymous_variant 0.46
rpoB 760982 c.1176G>C synonymous_variant 0.55
rpoB 760985 c.1179G>C synonymous_variant 0.54
rpoB 760991 c.1185G>C synonymous_variant 0.57
rpoB 761006 c.1200C>G synonymous_variant 0.59
rpoB 761015 c.1209G>C synonymous_variant 0.56
rpoB 761021 c.1215G>C synonymous_variant 0.57
rpoB 761027 c.1221A>G synonymous_variant 0.56
rpoB 761036 c.1230G>C synonymous_variant 0.53
rpoB 761037 c.1231T>C synonymous_variant 0.51
rpoB 761057 c.1251G>C synonymous_variant 0.47
rpoB 761165 c.1359G>C synonymous_variant 0.28
rpoB 761180 c.1374A>C synonymous_variant 0.26
rpoB 761249 c.1443A>G synonymous_variant 0.31
rpoB 761255 c.1449T>G synonymous_variant 0.31
rpoB 761261 c.1455G>T synonymous_variant 0.32
rpoB 761306 c.1500C>G synonymous_variant 0.37
rpoB 761327 c.1521A>G synonymous_variant 0.35
rpoB 761330 c.1524G>C synonymous_variant 0.31
rpoB 761354 c.1548C>T synonymous_variant 0.32
rpoB 761360 c.1554T>C synonymous_variant 0.31
rpoB 761362 p.Ser519Thr missense_variant 0.31
rpoB 761373 p.Val523His missense_variant 0.28
rpoB 761408 c.1602G>C synonymous_variant 0.21
rpoB 761477 c.1671C>G synonymous_variant 0.23
rpoB 761492 c.1686G>C synonymous_variant 0.23
rpoB 761510 c.1704T>C synonymous_variant 0.28
rpoB 761537 c.1731C>G synonymous_variant 0.42
rpoB 761570 c.1764T>C synonymous_variant 0.44
rpoB 761573 c.1767C>G synonymous_variant 0.44
rpoB 761579 c.1773G>C synonymous_variant 0.44
rpoB 761588 c.1782C>T synonymous_variant 0.46
rpoB 761606 c.1800C>G synonymous_variant 0.47
rpoB 761612 c.1806G>C synonymous_variant 0.48
rpoB 761615 c.1809A>C synonymous_variant 0.51
rpoB 761636 c.1830G>T synonymous_variant 0.5
rpoB 761639 c.1833G>A synonymous_variant 0.54
rpoB 761645 c.1839C>G synonymous_variant 0.52
rpoB 761648 c.1842T>C synonymous_variant 0.52
rpoB 761732 c.1926C>G synonymous_variant 0.19
rpoB 761948 c.2142G>C synonymous_variant 0.23
rpoB 761954 c.2148C>G synonymous_variant 0.24
rpoB 762008 c.2202C>T synonymous_variant 0.31
rpoB 762014 c.2208C>T synonymous_variant 0.29
rpoB 762017 c.2211A>G synonymous_variant 0.29
rpoB 762053 c.2247T>C synonymous_variant 0.23
rpoB 762062 c.2256T>C synonymous_variant 0.24
rpoB 762065 c.2259T>C synonymous_variant 0.24
rpoB 762086 c.2280G>C synonymous_variant 0.19
rpoB 762317 c.2511A>G synonymous_variant 0.22
rpoB 762329 c.2523G>C synonymous_variant 0.25
rpoB 762338 c.2532T>C synonymous_variant 0.29
rpoB 762347 c.2541T>C synonymous_variant 0.29
rpoB 762362 p.Glu852Asp missense_variant 0.3
rpoB 762369 c.2563T>C synonymous_variant 0.3
rpoC 762398 c.-972T>C upstream_gene_variant 0.37
rpoC 762401 c.-969G>C upstream_gene_variant 0.36
rpoC 762404 c.-966T>C upstream_gene_variant 0.38
rpoC 762410 c.-960T>C upstream_gene_variant 0.41
rpoC 762416 c.-954A>G upstream_gene_variant 0.42
rpoC 762419 c.-951C>G upstream_gene_variant 0.42
rpoC 762434 c.-936T>C upstream_gene_variant 0.44
rpoC 762449 c.-921C>A upstream_gene_variant 0.44
rpoC 762467 c.-903C>T upstream_gene_variant 0.46
rpoC 762488 c.-882G>C upstream_gene_variant 0.42
rpoB 762489 p.Val895Gln missense_variant 0.39
rpoC 762509 c.-861T>G upstream_gene_variant 0.37
rpoB 762510 p.Ala902Pro missense_variant 0.37
rpoC 762521 c.-849C>T upstream_gene_variant 0.38
rpoC 762533 c.-837T>C upstream_gene_variant 0.32
rpoC 762536 c.-834T>C upstream_gene_variant 0.31
rpoC 762537 c.-833T>C upstream_gene_variant 0.31
rpoC 762551 c.-819C>G upstream_gene_variant 0.33
rpoC 762581 c.-789T>C upstream_gene_variant 0.2
rpoC 762582 c.-788T>C upstream_gene_variant 0.2
rpoC 762758 c.-612G>C upstream_gene_variant 0.76
rpoC 762782 c.-588T>C upstream_gene_variant 0.76
rpoB 762785 p.Asp993Glu missense_variant 0.76
rpoC 762788 c.-582G>C upstream_gene_variant 0.74
rpoB 762789 p.Leu995Met missense_variant 0.74
rpoC 762794 c.-576C>G upstream_gene_variant 0.73
rpoB 762799 p.Ala998Gly missense_variant 0.74
rpoB 762810 p.Ala1002Ser missense_variant 0.65
rpoB 762813 p.Met1003Val missense_variant 0.64
rpoC 762818 c.-552C>G upstream_gene_variant 0.62
rpoC 762827 c.-543G>C upstream_gene_variant 0.61
rpoC 762857 c.-513C>G upstream_gene_variant 0.54
rpoC 762860 c.-510G>C upstream_gene_variant 0.53
rpoC 762863 c.-507T>C upstream_gene_variant 0.5
rpoC 762929 c.-441G>C upstream_gene_variant 0.41
rpoC 762989 c.-381G>C upstream_gene_variant 0.44
rpoC 762995 c.-375G>T upstream_gene_variant 0.45
rpoC 763013 c.-357C>G upstream_gene_variant 0.49
rpoC 763028 c.-342T>C upstream_gene_variant 0.47
rpoC 763031 c.-339T>C upstream_gene_variant 0.54
rpoC 763031 c.-339T>G upstream_gene_variant 0.46
rpoC 763034 c.-336C>G upstream_gene_variant 0.47
rpoC 763040 c.-330C>G upstream_gene_variant 0.5
rpoC 763070 c.-300T>C upstream_gene_variant 0.49
rpoC 763085 c.-285C>G upstream_gene_variant 0.48
rpoC 763115 c.-255T>C upstream_gene_variant 0.51
rpoC 763136 c.-234C>T upstream_gene_variant 0.55
rpoC 763148 c.-222G>C upstream_gene_variant 0.56
rpoC 763158 c.-212C>T upstream_gene_variant 0.56
rpoC 763166 c.-204A>G upstream_gene_variant 0.55
rpoC 763190 c.-180C>T upstream_gene_variant 0.5
rpoC 763202 c.-168A>G upstream_gene_variant 0.44
rpoC 763205 c.-165G>C upstream_gene_variant 0.44
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.44
rpoC 763214 c.-156T>C upstream_gene_variant 0.45
rpoC 763226 c.-144A>G upstream_gene_variant 0.45
rpoC 763227 c.-143C>T upstream_gene_variant 0.46
rpoC 763238 c.-132T>C upstream_gene_variant 0.44
rpoC 763253 c.-117G>C upstream_gene_variant 0.36
rpoC 763256 c.-114G>A upstream_gene_variant 0.36
rpoC 763268 c.-102C>G upstream_gene_variant 0.36
rpoC 763283 c.-87T>C upstream_gene_variant 0.23
rpoC 763284 c.-86C>T upstream_gene_variant 0.22
rpoC 763402 c.33C>G synonymous_variant 0.38
rpoC 763411 c.42T>G synonymous_variant 0.43
rpoC 763414 c.45T>C synonymous_variant 0.43
rpoC 763441 c.72C>T synonymous_variant 0.51
rpoC 763444 c.75T>C synonymous_variant 0.5
rpoC 763456 c.87A>G synonymous_variant 0.54
rpoC 763486 c.117T>G synonymous_variant 0.55
rpoC 763528 c.159G>A synonymous_variant 0.61
rpoC 763546 c.177A>G synonymous_variant 0.56
rpoC 763570 c.201G>C synonymous_variant 0.47
rpoC 763573 c.204G>C synonymous_variant 0.47
rpoC 763594 c.225C>T synonymous_variant 0.45
rpoC 763603 c.234C>T synonymous_variant 0.43
rpoC 763636 c.267T>C synonymous_variant 0.39
rpoC 763660 c.291T>G synonymous_variant 0.39
rpoC 763675 c.306C>G synonymous_variant 0.41
rpoC 763696 c.327T>C synonymous_variant 0.43
rpoC 763702 c.333C>G synonymous_variant 0.45
rpoC 763717 c.348T>C synonymous_variant 0.5
rpoC 763723 c.354G>C synonymous_variant 0.5
rpoC 763732 c.363C>G synonymous_variant 0.54
rpoC 763741 c.372C>T synonymous_variant 0.56
rpoC 763744 c.375G>C synonymous_variant 0.56
rpoC 763765 c.396T>C synonymous_variant 0.58
rpoC 763774 c.405G>C synonymous_variant 0.62
rpoC 763807 c.438T>C synonymous_variant 0.65
rpoC 763816 c.447C>G synonymous_variant 0.61
rpoC 763835 p.Ala156Met missense_variant 0.58
rpoC 763853 p.Val162Ile missense_variant 0.62
rpoC 763858 c.489A>G synonymous_variant 0.62
rpoC 763872 p.Gly168Ala missense_variant 0.57
rpoC 763876 p.Glu169Asp missense_variant 0.62
rpoC 763879 c.510A>G synonymous_variant 0.59
rpoC 763888 c.519G>C synonymous_variant 0.63
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 0.56
rpoC 764032 p.Asp221Glu missense_variant 0.55
rpoC 764040 p.Ser224Thr missense_variant 0.55
rpoC 764044 c.675T>C synonymous_variant 0.57
rpoC 764059 c.690G>T synonymous_variant 0.6
rpoC 764083 c.714A>G synonymous_variant 0.61
rpoC 764098 c.729A>G synonymous_variant 0.66
rpoC 764101 c.732C>G synonymous_variant 0.63
rpoC 764112 p.Tyr248Phe missense_variant 0.64
rpoC 764116 c.747C>T synonymous_variant 0.65
rpoC 764131 c.762T>C synonymous_variant 0.64
rpoC 764140 c.771C>T synonymous_variant 0.69
rpoC 764188 c.819A>G synonymous_variant 0.65
rpoC 764195 p.Ser276Ile missense_variant 0.6
rpoC 764203 c.834G>C synonymous_variant 0.61
rpoC 764206 c.837T>C synonymous_variant 0.63
rpoC 764215 c.846A>G synonymous_variant 0.64
rpoC 764236 c.867G>A synonymous_variant 0.63
rpoC 764248 c.879C>G synonymous_variant 0.62
rpoC 764257 c.888G>C synonymous_variant 0.63
rpoC 764266 c.897T>C synonymous_variant 0.59
rpoC 764269 c.900G>C synonymous_variant 0.58
rpoC 764272 c.903G>C synonymous_variant 0.59
rpoC 764278 c.909A>G synonymous_variant 0.61
rpoC 764338 c.969G>A synonymous_variant 0.63
rpoC 764353 c.984G>C synonymous_variant 0.59
rpoC 764365 c.996C>T synonymous_variant 0.55
rpoC 764380 c.1011G>C synonymous_variant 0.38
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.38
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.38
rpoC 764446 c.1077T>C synonymous_variant 0.28
rpoC 764449 c.1080G>C synonymous_variant 0.27
rpoC 764452 c.1083T>C synonymous_variant 0.29
rpoC 764458 c.1089G>C synonymous_variant 0.3
rpoC 764461 c.1092A>G synonymous_variant 0.33
rpoC 764489 c.1120C>T synonymous_variant 0.49
rpoC 764497 c.1128A>G synonymous_variant 0.52
rpoC 764510 c.1141C>T synonymous_variant 0.54
rpoC 764521 c.1152T>C synonymous_variant 0.59
rpoC 764527 c.1158C>T synonymous_variant 0.61
rpoC 764536 c.1167G>C synonymous_variant 0.57
rpoC 764539 c.1170C>G synonymous_variant 0.6
rpoC 764554 c.1185C>T synonymous_variant 0.59
rpoC 764560 c.1191T>C synonymous_variant 0.63
rpoC 764566 c.1197C>G synonymous_variant 0.65
rpoC 764575 c.1206T>G synonymous_variant 0.62
rpoC 764581 c.1212T>C synonymous_variant 0.62
rpoC 764593 c.1224C>T synonymous_variant 0.66
rpoC 764611 c.1242G>T synonymous_variant 0.67
rpoC 764650 c.1281G>C synonymous_variant 0.55
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.55
rpoC 764752 c.1383G>C synonymous_variant 0.41
rpoC 764764 c.1395T>C synonymous_variant 0.4
rpoC 764809 c.1440C>T synonymous_variant 0.42
rpoC 764815 c.1446A>G synonymous_variant 0.45
rpoC 764827 c.1458G>C synonymous_variant 0.46
rpoC 764858 c.1489T>C synonymous_variant 0.44
rpoC 764872 c.1503A>G synonymous_variant 0.43
rpoC 764888 c.1519T>C synonymous_variant 0.45
rpoC 764911 c.1542A>G synonymous_variant 0.44
rpoC 764932 c.1563C>A synonymous_variant 0.45
rpoC 764935 c.1566T>C synonymous_variant 0.45
rpoC 764948 c.1579T>C synonymous_variant 0.45
rpoC 764968 c.1599T>C synonymous_variant 0.45
rpoC 764995 c.1626C>G synonymous_variant 0.46
rpoC 765019 c.1650A>G synonymous_variant 0.42
rpoC 765034 c.1665T>C synonymous_variant 0.38
rpoC 765040 c.1671T>C synonymous_variant 0.34
rpoC 765041 c.1672T>C synonymous_variant 0.34
rpoC 765047 c.1678T>C synonymous_variant 0.33
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 0.34
rpoC 765073 c.1704G>C synonymous_variant 0.31
rpoC 765076 c.1707A>G synonymous_variant 0.3
rpoC 765079 c.1710T>G synonymous_variant 0.31
rpoC 765082 c.1713G>C synonymous_variant 0.3
rpoC 765089 c.1720T>C synonymous_variant 0.3
rpoC 765103 c.1734G>T synonymous_variant 0.3
rpoC 765383 p.Met672Leu missense_variant 0.7
rpoC 765404 p.Leu679Val missense_variant 0.72
rpoC 765409 c.2040T>C synonymous_variant 0.71
rpoC 765421 c.2052C>G synonymous_variant 0.71
rpoC 765478 c.2109T>C synonymous_variant 0.69
rpoC 765499 c.2130C>G synonymous_variant 0.68
rpoC 765529 c.2160C>T synonymous_variant 0.67
rpoC 765541 c.2172C>G synonymous_variant 0.63
rpoC 765553 c.2184C>T synonymous_variant 0.64
rpoC 765556 c.2187G>C synonymous_variant 0.63
rpoC 765559 c.2190G>C synonymous_variant 0.63
rpoC 765580 c.2211G>C synonymous_variant 0.63
rpoC 765613 p.His748Gln missense_variant 0.61
rpoC 765625 c.2256C>G synonymous_variant 0.61
rpoC 765631 p.Asp754Glu missense_variant 0.6
rpoC 765700 c.2331T>C synonymous_variant 0.61
rpoC 765734 c.2365T>C synonymous_variant 0.65
rpoC 765739 c.2370G>T synonymous_variant 0.64
rpoC 765751 c.2382C>G synonymous_variant 0.63
rpoC 765753 p.Asp795Ala missense_variant 0.63
rpoC 765772 c.2403C>G synonymous_variant 0.64
rpoC 765784 c.2415C>G synonymous_variant 0.62
rpoC 765787 c.2418C>T synonymous_variant 0.63
rpoC 765793 c.2424C>G synonymous_variant 0.64
rpoC 765796 c.2427C>T synonymous_variant 0.64
rpoC 765811 c.2442T>C synonymous_variant 0.66
rpoC 765814 c.2445A>G synonymous_variant 0.65
rpoC 765826 c.2457T>C synonymous_variant 0.64
rpoC 765835 c.2466C>T synonymous_variant 0.67
rpoC 765850 c.2481G>C synonymous_variant 0.68
rpoC 765883 c.2514C>G synonymous_variant 0.65
rpoC 765886 c.2517C>G synonymous_variant 0.66
rpoC 765892 c.2523T>C synonymous_variant 0.65
rpoC 765937 c.2568T>C synonymous_variant 0.7
rpoC 765967 c.2598C>T synonymous_variant 0.7
rpoC 765982 c.2613C>G synonymous_variant 0.74
rpoC 765994 c.2625A>T synonymous_variant 0.75
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.76
rpoC 766021 c.2652G>C synonymous_variant 0.82
rpoC 766027 c.2658G>C synonymous_variant 0.83
rpoC 766030 c.2661C>G synonymous_variant 0.83
rpoC 766036 c.2667C>T synonymous_variant 0.83
rpoC 766043 p.Gln892Glu missense_variant 0.84
rpoC 766054 c.2685C>G synonymous_variant 0.88
rpoC 766082 p.Ala905Gln missense_variant 0.72
rpoC 766096 c.2727G>C synonymous_variant 0.73
rpoC 766129 c.2760C>G synonymous_variant 0.49
rpoC 766135 c.2766G>A synonymous_variant 0.44
rpoC 766141 c.2772C>T synonymous_variant 0.38
rpoC 766142 c.2773C>T synonymous_variant 0.38
rpoC 766168 c.2799C>T synonymous_variant 0.21
rpoC 766288 c.2919C>G synonymous_variant 0.33
rpoC 766303 c.2934C>T synonymous_variant 0.43
rpoC 766312 c.2943T>G synonymous_variant 0.51
rpoC 766327 c.2958C>A synonymous_variant 0.54
rpoC 766345 c.2976T>C synonymous_variant 0.57
rpoC 766348 c.2979A>G synonymous_variant 0.59
rpoC 766357 c.2988C>T synonymous_variant 0.6
rpoC 766363 c.2994G>C synonymous_variant 0.62
rpoC 766381 c.3012C>T synonymous_variant 0.67
rpoC 766384 c.3015A>G synonymous_variant 0.67
rpoC 766408 c.3039C>G synonymous_variant 0.73
rpoC 766411 c.3042C>G synonymous_variant 0.74
rpoC 766426 c.3057C>T synonymous_variant 0.79
rpoC 766447 c.3078T>C synonymous_variant 0.63
rpoC 766462 c.3093G>C synonymous_variant 0.54
rpoC 766522 c.3153C>G synonymous_variant 0.4
rpoC 766528 c.3159T>C synonymous_variant 0.38
rpoC 766531 c.3162G>C synonymous_variant 0.36
rpoC 766540 p.Asp1057Glu missense_variant 0.4
rpoC 766549 c.3180G>C synonymous_variant 0.35
rpoC 766573 c.3204T>C synonymous_variant 0.32
rpoC 766582 c.3213C>G synonymous_variant 0.3
rpoC 766583 p.Gly1072Ser missense_variant 0.29
rpoC 766591 c.3222A>G synonymous_variant 0.3
rpoC 766594 c.3225G>C synonymous_variant 0.28
rpoC 766597 c.3228C>G synonymous_variant 0.3
rpoC 766607 p.Ile1080Leu missense_variant 0.33
rpoC 766630 c.3261G>C synonymous_variant 0.34
rpoC 766657 c.3288A>G synonymous_variant 0.38
rpoC 766672 c.3303T>C synonymous_variant 0.34
rpoC 766673 p.Gly1102Asn missense_variant 0.35
rpoC 766726 c.3357T>C synonymous_variant 0.32
rpoC 766738 c.3369G>C synonymous_variant 0.32
rpoC 766765 c.3396A>C synonymous_variant 0.35
rpoC 766774 c.3405T>C synonymous_variant 0.39
rpoC 766801 c.3432C>G synonymous_variant 0.41
rpoC 766804 c.3435A>G synonymous_variant 0.4
rpoC 766861 c.3492G>C synonymous_variant 0.37
rpoC 766864 c.3495G>C synonymous_variant 0.38
rpoC 766900 c.3531T>C synonymous_variant 0.37
rpoC 766996 c.3627C>T synonymous_variant 0.68
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.57
rpoC 767014 c.3645G>C synonymous_variant 0.57
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 0.62
rpoC 767059 c.3690T>G synonymous_variant 0.65
rpoC 767062 c.3693C>A synonymous_variant 0.65
rpoC 767098 c.3729T>C synonymous_variant 0.63
rpoC 767119 c.3750A>G synonymous_variant 0.62
rpoC 767134 c.3765C>A synonymous_variant 0.6
rpoC 767158 c.3789T>C synonymous_variant 0.6
rpoC 767180 p.Ala1271Gln missense_variant 0.54
rpoC 767191 c.3822C>G synonymous_variant 0.53
rpoC 767206 c.3837C>G synonymous_variant 0.48
rpoC 767209 c.3840T>C synonymous_variant 0.49
rpoC 767212 c.3843G>C synonymous_variant 0.47
rpoC 767221 c.3852C>G synonymous_variant 0.45
rpoC 767230 c.3861G>C synonymous_variant 0.43
rpoC 767233 c.3864T>C synonymous_variant 0.42
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776182 p.Asp767Asn missense_variant 1.0
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781571 c.12C>T synonymous_variant 0.22
rpsL 781595 c.36T>C synonymous_variant 0.29
rpsL 781605 p.Ile16Val missense_variant 0.27
rpsL 781608 p.Ser17Ala missense_variant 0.28
rpsL 781628 c.69T>C synonymous_variant 0.42
rpsL 781631 c.72G>C synonymous_variant 0.45
rpsL 781649 c.90T>C synonymous_variant 0.49
rpsL 781655 c.96T>C synonymous_variant 0.5
rpsL 781700 c.141G>C synonymous_variant 0.58
rpsL 781703 c.144G>T synonymous_variant 0.57
rpsL 781715 c.156T>C synonymous_variant 0.59
rpsL 781728 c.169T>C synonymous_variant 0.6
rpsL 781736 c.177T>C synonymous_variant 0.58
rpsL 781742 c.183C>T synonymous_variant 0.59
rpsL 781748 c.189C>G synonymous_variant 0.59
rpsL 781754 c.195G>C synonymous_variant 0.6
rpsL 781760 c.201T>C synonymous_variant 0.62
rpsL 781772 c.213C>A synonymous_variant 0.61
rpsL 781808 c.249C>T synonymous_variant 0.65
rpsL 781811 c.252C>T synonymous_variant 0.65
rpsL 781832 c.273T>C synonymous_variant 0.61
rpsL 781838 c.279G>C synonymous_variant 0.59
rpsL 781841 c.282C>G synonymous_variant 0.6
rpsL 781865 c.306G>C synonymous_variant 0.57
rpsL 781868 c.309T>C synonymous_variant 0.57
rpsL 781871 c.312G>C synonymous_variant 0.57
rpsL 781877 c.318T>C synonymous_variant 0.56
rpsL 781892 c.333A>G synonymous_variant 0.58
rpsL 781898 c.339A>T synonymous_variant 0.6
rpsL 781916 c.357T>C synonymous_variant 0.59
rpsL 781929 p.Gly124Ser missense_variant 0.6
rplC 800612 c.-197A>G upstream_gene_variant 0.4
rplC 800618 c.-191T>C upstream_gene_variant 0.44
rplC 800627 c.-182C>T upstream_gene_variant 0.44
rplC 800648 c.-161A>T upstream_gene_variant 0.5
rplC 800654 c.-155T>C upstream_gene_variant 0.47
rplC 800693 c.-116A>G upstream_gene_variant 0.5
rplC 800703 c.-106T>C upstream_gene_variant 0.51
rplC 800715 c.-94A>C upstream_gene_variant 0.5
rplC 800720 c.-89T>C upstream_gene_variant 0.51
rplC 800723 c.-86C>G upstream_gene_variant 0.52
rplC 800747 c.-62C>G upstream_gene_variant 0.48
rplC 800771 c.-38C>T upstream_gene_variant 0.5
rplC 800794 c.-15A>G upstream_gene_variant 0.39
rplC 800796 c.-13A>G upstream_gene_variant 0.4
rplC 800798 c.-10_-9delGG upstream_gene_variant 0.42
rplC 800814 c.6A>G synonymous_variant 0.43
rplC 800817 c.9A>T synonymous_variant 0.43
rplC 800844 c.36T>C synonymous_variant 0.4
rplC 800865 c.57A>G synonymous_variant 0.37
rplC 800867 p.Ser20Asn missense_variant 0.36
rplC 800874 c.66A>G synonymous_variant 0.32
rplC 800875 p.Val23Ile missense_variant 0.3
rplC 800880 c.72A>G synonymous_variant 0.3
rplC 800889 c.81C>G synonymous_variant 0.33
rplC 800892 c.84G>C synonymous_variant 0.32
rplC 800907 c.99C>G synonymous_variant 0.3
rplC 800916 c.108A>G synonymous_variant 0.24
rplC 801282 c.474G>C synonymous_variant 0.51
rplC 801285 c.477G>C synonymous_variant 0.5
rplC 801300 c.492C>G synonymous_variant 0.51
rplC 801309 c.501C>G synonymous_variant 0.47
rplC 801312 c.504G>C synonymous_variant 0.51
rplC 801321 c.513C>T synonymous_variant 0.52
rplC 801324 c.516T>C synonymous_variant 0.53
rplC 801339 c.531T>C synonymous_variant 0.49
rplC 801341 p.Leu178Gln missense_variant 0.49
rplC 801348 c.540T>G synonymous_variant 0.48
rplC 801357 c.549T>C synonymous_variant 0.46
rplC 801367 p.Ala187Thr missense_variant 0.45
rplC 801402 c.594T>C synonymous_variant 0.45
rplC 801405 c.597T>C synonymous_variant 0.45
rplC 801423 c.615G>C synonymous_variant 0.45
rplC 801426 c.618C>G synonymous_variant 0.46
rplC 801427 p.Met207Val missense_variant 0.47
rplC 801438 c.630T>C synonymous_variant 0.46
rplC 801442 p.Ile212Val missense_variant 0.52
fbiC 1304499 c.1569T>C synonymous_variant 0.27
fbiC 1304511 c.1581C>G synonymous_variant 0.31
fbiC 1304526 c.1596T>G synonymous_variant 0.31
fbiC 1304535 c.1605G>A synonymous_variant 0.31
fbiC 1304544 c.1614T>C synonymous_variant 0.3
fbiC 1304545 p.Val539Thr missense_variant 0.31
fbiC 1304553 c.1623C>T synonymous_variant 0.26
fbiC 1304559 p.Glu543Asp missense_variant 0.27
fbiC 1304565 c.1635C>G synonymous_variant 0.28
fbiC 1304568 c.1638T>C synonymous_variant 0.27
fbiC 1304580 c.1650T>C synonymous_variant 0.26
fbiC 1304634 c.1704C>G synonymous_variant 0.19
fbiC 1304856 c.1926C>G synonymous_variant 0.19
fbiC 1304869 c.1939C>T synonymous_variant 0.21
fbiC 1304875 p.Ile649Val missense_variant 0.21
fbiC 1304883 p.Glu651Asp missense_variant 0.23
fbiC 1304891 p.Ile654Thr missense_variant 0.26
fbiC 1304893 p.Gly655Ser missense_variant 0.27
fbiC 1304907 c.1977C>G synonymous_variant 0.3
fbiC 1304910 c.1980G>C synonymous_variant 0.32
fbiC 1304916 c.1986T>C synonymous_variant 0.31
fbiC 1304928 c.1998T>C synonymous_variant 0.32
fbiC 1304937 c.2007G>C synonymous_variant 0.31
fbiC 1304958 c.2028T>G synonymous_variant 0.3
fbiC 1304983 c.2053C>T synonymous_variant 0.27
fbiC 1304994 c.2064A>G synonymous_variant 0.25
fbiC 1304995 p.Leu689Met missense_variant 0.25
fbiC 1305006 c.2076A>G synonymous_variant 0.24
fbiC 1305012 c.2082G>C synonymous_variant 0.2
fbiC 1305015 c.2085G>C synonymous_variant 0.21
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0
atpE 1460852 c.-193C>G upstream_gene_variant 0.28
atpE 1460855 c.-190T>C upstream_gene_variant 0.27
atpE 1460858 c.-187C>G upstream_gene_variant 0.26
atpE 1460861 c.-184C>G upstream_gene_variant 0.26
atpE 1460882 c.-163T>C upstream_gene_variant 0.24
atpE 1460894 c.-151A>G upstream_gene_variant 0.21
atpE 1460897 c.-148A>C upstream_gene_variant 0.21
atpE 1460900 c.-145T>C upstream_gene_variant 0.2
atpE 1460915 c.-130C>G upstream_gene_variant 0.2
atpE 1460918 c.-127A>G upstream_gene_variant 0.2
atpE 1461089 c.45G>C synonymous_variant 0.22
atpE 1461097 p.Ala18Gly missense_variant 0.25
atpE 1461101 c.57T>C synonymous_variant 0.27
atpE 1461107 c.63C>G synonymous_variant 0.28
atpE 1461113 c.69C>T synonymous_variant 0.34
atpE 1461132 p.Val30Ile missense_variant 0.37
atpE 1461149 c.105T>G synonymous_variant 0.39
atpE 1461150 p.Ile36Val missense_variant 0.38
atpE 1461158 c.114T>G synonymous_variant 0.38
atpE 1461159 p.Val39Ile missense_variant 0.38
atpE 1461170 c.126A>G synonymous_variant 0.38
atpE 1461185 c.141G>T synonymous_variant 0.36
atpE 1461197 c.153A>G synonymous_variant 0.38
atpE 1461219 c.175T>C synonymous_variant 0.4
atpE 1461233 c.189A>C synonymous_variant 0.33
atpE 1461251 c.207G>C synonymous_variant 0.24
atpE 1461254 c.210T>C synonymous_variant 0.22
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.34
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.33
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.31
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.31
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.35
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.35
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.28
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.39
rrs 1472300 n.455C>T non_coding_transcript_exon_variant 0.58
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.64
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.64
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.59
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.61
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.56
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.57
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.61
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.59
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.47
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.47
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.47
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.43
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.43
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.47
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.46
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.55
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.44
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.4
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.4
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.57
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.58
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.6
rrl 1474409 n.756_766delACCCACACGCG non_coding_transcript_exon_variant 0.55
rrl 1474427 n.770A>C non_coding_transcript_exon_variant 0.49
rrl 1474429 n.772G>C non_coding_transcript_exon_variant 0.48
rrl 1474431 n.774_775delGCinsTTTGGG non_coding_transcript_exon_variant 0.49
rrl 1474435 n.780_783delGAAT non_coding_transcript_exon_variant 0.5
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.68
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.68
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.67
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.69
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.67
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.49
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.21
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.51
rrl 1475028 n.1371G>A non_coding_transcript_exon_variant 0.63
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.68
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.69
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.59
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.58
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.58
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.58
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.59
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.58
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.57
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.56
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.56
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.56
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.6
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.57
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.54
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.5
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.43
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.51
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.55
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.58
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.62
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 0.6
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.61
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.6
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.6
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.57
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.57
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.65
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.67
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.74
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.58
rrl 1476031 n.2374C>T non_coding_transcript_exon_variant 0.48
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.48
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.48
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.49
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.48
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.48
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.48
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.48
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.53
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.5
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.5
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.48
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.48
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.47
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.48
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.44
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.44
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.45
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.34
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.34
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.33
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.39
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.36
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.37
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.43
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.43
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.39
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.39
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.38
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.4
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.35
inhA 1674480 c.279T>C synonymous_variant 0.21
inhA 1674486 c.285T>C synonymous_variant 0.24
inhA 1674504 c.303C>G synonymous_variant 0.34
inhA 1674537 c.336C>G synonymous_variant 0.33
inhA 1674542 p.Ala114Glu missense_variant 0.31
inhA 1674546 c.345T>C synonymous_variant 0.31
inhA 1674549 c.348G>C synonymous_variant 0.26
inhA 1674552 c.351C>G synonymous_variant 0.28
inhA 1674555 c.354G>A synonymous_variant 0.26
inhA 1674561 c.360C>T synonymous_variant 0.3
inhA 1674582 c.381T>C synonymous_variant 0.28
inhA 1674585 c.384T>C synonymous_variant 0.31
inhA 1674589 p.Met130Leu missense_variant 0.31
inhA 1674601 p.Leu134Thr missense_variant 0.29
inhA 1674624 c.423A>C synonymous_variant 0.26
inhA 1674630 c.429C>G synonymous_variant 0.24
inhA 1674660 c.459G>C synonymous_variant 0.26
inhA 1674672 c.471C>G synonymous_variant 0.27
inhA 1674703 c.502T>C synonymous_variant 0.25
inhA 1674708 c.507G>A synonymous_variant 0.28
inhA 1674718 c.517A>C synonymous_variant 0.27
inhA 1674723 c.522C>T synonymous_variant 0.29
inhA 1674801 c.600T>C synonymous_variant 0.24
inhA 1674846 p.Ile215Met missense_variant 0.45
inhA 1674855 c.654C>G synonymous_variant 0.55
inhA 1674864 c.663C>T synonymous_variant 0.5
inhA 1674870 c.669T>C synonymous_variant 0.49
inhA 1674879 c.678T>C synonymous_variant 0.52
inhA 1674903 c.702T>C synonymous_variant 0.43
inhA 1674904 p.Ala235Pro missense_variant 0.42
inhA 1674909 c.708G>A synonymous_variant 0.42
inhA 1674942 c.741T>G synonymous_variant 0.29
inhA 1674960 c.759C>G synonymous_variant 0.26
inhA 1674966 c.765T>G synonymous_variant 0.24
inhA 1674967 p.Asp256Thr missense_variant 0.22
rpsA 1833532 c.-10A>C upstream_gene_variant 0.34
rpsA 1833554 p.Thr5Ala missense_variant 0.41
rpsA 1833568 c.27G>C synonymous_variant 0.47
rpsA 1833589 c.48A>T synonymous_variant 0.47
rpsA 1833595 c.54T>C synonymous_variant 0.48
rpsA 1833661 c.120A>G synonymous_variant 0.56
rpsA 1833667 c.126C>G synonymous_variant 0.58
rpsA 1833721 c.180A>G synonymous_variant 0.61
rpsA 1833724 c.183C>G synonymous_variant 0.58
rpsA 1833727 c.186G>C synonymous_variant 0.58
rpsA 1833742 c.201A>G synonymous_variant 0.62
rpsA 1833745 c.204G>C synonymous_variant 0.57
rpsA 1833748 c.207C>G synonymous_variant 0.57
rpsA 1833787 c.246C>G synonymous_variant 0.6
rpsA 1833790 c.249T>C synonymous_variant 0.6
rpsA 1833802 c.261A>G synonymous_variant 0.58
rpsA 1833811 c.270G>T synonymous_variant 0.57
rpsA 1833838 c.297G>C synonymous_variant 0.55
rpsA 1833841 c.300C>G synonymous_variant 0.55
rpsA 1833847 c.306C>G synonymous_variant 0.55
rpsA 1833856 c.315A>G synonymous_variant 0.53
rpsA 1833874 c.333T>C synonymous_variant 0.48
rpsA 1833886 c.345C>G synonymous_variant 0.48
rpsA 1833928 c.387G>C synonymous_variant 0.51
rpsA 1833940 c.399C>G synonymous_variant 0.52
rpsA 1833971 c.430C>T synonymous_variant 0.49
rpsA 1833979 c.438T>C synonymous_variant 0.46
rpsA 1834000 c.459G>C synonymous_variant 0.41
rpsA 1834021 c.480C>T synonymous_variant 0.41
rpsA 1834030 c.489C>G synonymous_variant 0.39
rpsA 1834081 c.540C>T synonymous_variant 0.25
rpsA 1834177 c.636A>C synonymous_variant 0.99
rpsA 1834189 c.648G>C synonymous_variant 0.28
rpsA 1834195 c.654G>C synonymous_variant 0.31
rpsA 1834210 c.669C>T synonymous_variant 0.34
rpsA 1834222 c.681T>C synonymous_variant 0.35
rpsA 1834231 c.690T>C synonymous_variant 0.33
rpsA 1834234 c.693G>C synonymous_variant 0.35
rpsA 1834249 c.708T>C synonymous_variant 0.4
rpsA 1834261 c.720A>G synonymous_variant 0.39
rpsA 1834262 c.721_723delTCGinsAGC synonymous_variant 0.39
rpsA 1834303 c.762T>C synonymous_variant 0.42
rpsA 1834306 c.765T>C synonymous_variant 0.41
rpsA 1834348 c.807T>C synonymous_variant 0.32
rpsA 1834366 c.825A>G synonymous_variant 0.31
rpsA 1834654 p.Glu371Asp missense_variant 0.22
rpsA 1834690 c.1149T>C synonymous_variant 0.3
rpsA 1834732 c.1191T>C synonymous_variant 0.45
rpsA 1834733 p.Ala398Ser missense_variant 0.45
rpsA 1834738 c.1197A>G synonymous_variant 0.45
rpsA 1834753 c.1212T>C synonymous_variant 0.47
rpsA 1834765 p.Glu408Asp missense_variant 0.5
rpsA 1834775 p.Ala412Thr missense_variant 0.46
rpsA 1834780 c.1239A>G synonymous_variant 0.45
rpsA 1834786 c.1245A>G synonymous_variant 0.42
rpsA 1834789 c.1248T>C synonymous_variant 0.4
rpsA 1834792 c.1251G>C synonymous_variant 0.39
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2517950 c.-165C>G upstream_gene_variant 0.56
kasA 2517989 c.-126T>C upstream_gene_variant 0.44
kasA 2517993 c.-122G>T upstream_gene_variant 0.41
kasA 2518019 c.-96A>G upstream_gene_variant 0.31
kasA 2518025 c.-90G>C upstream_gene_variant 0.25
kasA 2518132 c.18C>T synonymous_variant 0.24
kasA 2518138 c.24T>C synonymous_variant 0.27
kasA 2518146 p.Phe11Tyr missense_variant 0.26
kasA 2518162 c.48G>A synonymous_variant 0.25
kasA 2518174 c.60A>G synonymous_variant 0.25
kasA 2518190 p.Ser26Ala missense_variant 0.26
kasA 2518199 p.Ile29Val missense_variant 0.26
kasA 2518220 c.106C>T synonymous_variant 0.24
kasA 2518234 c.120G>A synonymous_variant 0.23
kasA 2518248 p.Ala45Val missense_variant 0.24
kasA 2518777 c.663C>T synonymous_variant 0.21
kasA 2518783 c.669T>C synonymous_variant 0.2
kasA 2518795 c.681C>G synonymous_variant 0.19
kasA 2519158 c.1044C>T synonymous_variant 0.32
kasA 2519167 c.1053T>G synonymous_variant 0.31
kasA 2519173 c.1059C>G synonymous_variant 0.29
Rv2752c 3065946 p.Gly82Ala missense_variant 0.21
Rv2752c 3065955 c.235_237delTTGinsCTC synonymous_variant 0.23
Rv2752c 3065979 c.213T>C synonymous_variant 0.27
Rv2752c 3065993 p.Val67Ile missense_variant 0.31
Rv2752c 3065994 c.198T>C synonymous_variant 0.31
Rv2752c 3066002 p.Met64Leu missense_variant 0.39
Rv2752c 3066009 c.183G>C synonymous_variant 0.42
Rv2752c 3066018 c.174T>C synonymous_variant 0.42
Rv2752c 3066024 c.168T>G synonymous_variant 0.4
Rv2752c 3066040 p.Gly51Thr missense_variant 0.39
Rv2752c 3066042 c.150T>C synonymous_variant 0.38
Rv2752c 3066045 c.147T>C synonymous_variant 0.39
Rv2752c 3066050 p.Leu48Met missense_variant 0.41
Rv2752c 3066054 c.138T>G synonymous_variant 0.41
Rv2752c 3066066 c.126T>C synonymous_variant 0.4
Rv2752c 3066075 c.117A>G synonymous_variant 0.4
Rv2752c 3066102 c.90C>T synonymous_variant 0.38
Rv2752c 3066118 p.Asn25Ser missense_variant 0.36
thyX 3067549 p.Thr133Ala missense_variant 0.71
thyX 3067556 p.His130Gln missense_variant 0.61
thyX 3067559 c.387C>G synonymous_variant 0.63
thyX 3067565 p.Asp127Glu missense_variant 0.57
thyX 3067570 p.Ala126Pro missense_variant 0.55
thyX 3067577 c.369G>A synonymous_variant 0.57
thyX 3067601 p.Arg115His missense_variant 0.5
thyX 3067611 p.Lys112Thr missense_variant 0.45
thyX 3067619 c.327A>C synonymous_variant 0.41
thyX 3067631 c.315C>G synonymous_variant 0.38
thyX 3067634 c.312C>G synonymous_variant 0.39
thyX 3067652 c.294T>C synonymous_variant 0.35
thyX 3067661 c.285C>G synonymous_variant 0.35
thyX 3067685 c.261A>C synonymous_variant 0.29
thyX 3067691 p.Ile85Leu missense_variant 0.25
thyX 3067694 c.252G>C synonymous_variant 0.25
thyA 3073839 c.633T>C synonymous_variant 0.25
thyA 3073860 c.612C>G synonymous_variant 0.25
thyA 3073863 c.609T>C synonymous_variant 0.24
thyA 3073866 c.606C>G synonymous_variant 0.25
thyA 3073872 p.Ile200Val missense_variant 0.25
thyA 3073892 c.580T>C synonymous_variant 0.27
thyA 3073898 p.Ala192Ser missense_variant 0.27
thyA 3073917 c.555C>G synonymous_variant 0.28
thyA 3073920 c.552C>G synonymous_variant 0.28
thyA 3073923 c.547_549delTTGinsCTA synonymous_variant 0.28
thyA 3073929 c.543T>C synonymous_variant 0.27
thyA 3073947 c.525G>A synonymous_variant 0.26
thyA 3073953 c.519T>C synonymous_variant 0.22
thyA 3073956 c.516G>C synonymous_variant 0.21
thyA 3073959 c.513T>C synonymous_variant 0.21
thyA 3074004 c.468T>C synonymous_variant 0.21
thyA 3074010 c.462C>G synonymous_variant 0.22
thyA 3074028 c.444G>C synonymous_variant 0.24
thyA 3074031 c.441T>C synonymous_variant 0.25
thyA 3074037 c.435C>G synonymous_variant 0.26
thyA 3074053 p.Arg140Gln missense_variant 0.21
thyA 3074055 p.Glu139Pro missense_variant 0.21
thyA 3074061 c.411A>G synonymous_variant 0.22
thyA 3074079 c.393G>C synonymous_variant 0.3
thyA 3074097 c.375C>G synonymous_variant 0.35
thyA 3074100 p.Asp124Asn missense_variant 0.35
thyA 3074106 c.366T>C synonymous_variant 0.36
thyA 3074127 c.345G>C synonymous_variant 0.36
thyA 3074130 c.342G>C synonymous_variant 0.37
thyA 3074154 c.318T>C synonymous_variant 0.33
thyA 3074157 c.315C>G synonymous_variant 0.32
thyA 3074160 c.312A>G synonymous_variant 0.32
thyA 3074163 p.Ala103Thr missense_variant 0.32
thyA 3074172 c.300G>C synonymous_variant 0.34
thyA 3074175 c.297A>G synonymous_variant 0.33
thyA 3074181 c.291A>G synonymous_variant 0.31
thyA 3074187 c.285T>C synonymous_variant 0.31
thyA 3074205 p.Glu89Asp missense_variant 0.32
thyA 3074214 c.258T>C synonymous_variant 0.29
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473809 c.-198G>C upstream_gene_variant 0.33
fprA 3473812 c.-195G>A upstream_gene_variant 0.34
fprA 3473843 c.-164C>G upstream_gene_variant 0.26
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3475074 c.1068C>G synonymous_variant 0.28
fprA 3475104 c.1098G>C synonymous_variant 0.24
fprA 3475107 c.1101G>C synonymous_variant 0.24
fprA 3475113 c.1107G>C synonymous_variant 0.24
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
rpoA 3877515 c.993G>C synonymous_variant 0.21
rpoA 3877553 p.Glu319Gln missense_variant 0.34
rpoA 3877571 p.Pro313Ala missense_variant 0.36
rpoA 3877587 c.921A>G synonymous_variant 0.44
rpoA 3877613 p.Ile299Val missense_variant 0.5
rpoA 3877656 c.852T>G synonymous_variant 0.48
rpoA 3877668 c.840A>G synonymous_variant 0.47
rpoA 3877679 p.Ala277Ser missense_variant 0.47
rpoA 3877686 c.822A>G synonymous_variant 0.44
rpoA 3877692 c.816G>C synonymous_variant 0.42
rpoA 3877704 c.804G>C synonymous_variant 0.41
rpoA 3877743 c.765T>C synonymous_variant 0.28
rpoA 3877764 c.744C>G synonymous_variant 0.22
rpoA 3877770 c.738A>G synonymous_variant 0.23
rpoA 3877776 c.732T>C synonymous_variant 0.26
rpoA 3877782 c.726T>C synonymous_variant 0.28
rpoA 3877791 c.717C>G synonymous_variant 0.3
rpoA 3877818 c.690A>G synonymous_variant 0.4
rpoA 3877839 c.669G>C synonymous_variant 0.43
rpoA 3877848 c.660C>T synonymous_variant 0.47
rpoA 3877857 c.651G>A synonymous_variant 0.47
rpoA 3877866 c.642G>C synonymous_variant 0.51
rpoA 3877875 c.633T>G synonymous_variant 0.51
rpoA 3877878 c.630G>C synonymous_variant 0.51
rpoA 3877890 c.618C>T synonymous_variant 0.54
rpoA 3877896 c.612G>C synonymous_variant 0.55
rpoA 3877900 p.Ser203Asn missense_variant 0.54
rpoA 3877905 c.603A>G synonymous_variant 0.53
rpoA 3877909 p.Asn200Ser missense_variant 0.55
rpoA 3877920 c.588G>C synonymous_variant 0.55
rpoA 3877923 c.585C>T synonymous_variant 0.52
rpoA 3877926 c.582G>C synonymous_variant 0.52
rpoA 3877962 c.546G>T synonymous_variant 0.54
rpoA 3877969 p.Ala180Val missense_variant 0.46
rpoA 3877986 c.522G>C synonymous_variant 0.53
rpoA 3877989 c.519A>G synonymous_variant 0.53
rpoA 3878001 c.507A>G synonymous_variant 0.48
rpoA 3878022 c.486T>C synonymous_variant 0.43
rpoA 3878028 c.480G>C synonymous_variant 0.42
rpoA 3878031 c.477T>C synonymous_variant 0.42
rpoA 3878040 c.468T>C synonymous_variant 0.42
rpoA 3878043 c.465G>A synonymous_variant 0.42
rpoA 3878055 c.453A>G synonymous_variant 0.4
rpoA 3878058 c.450G>T synonymous_variant 0.39
rpoA 3878061 c.447G>C synonymous_variant 0.37
rpoA 3878067 c.441C>G synonymous_variant 0.36
rpoA 3878070 c.438T>C synonymous_variant 0.35
rpoA 3878076 c.432C>T synonymous_variant 0.36
rpoA 3878082 c.426T>G synonymous_variant 0.35
rpoA 3878094 c.414C>G synonymous_variant 0.34
rpoA 3878103 c.405A>G synonymous_variant 0.33
rpoA 3878106 c.402G>C synonymous_variant 0.34
rpoA 3878118 c.390T>C synonymous_variant 0.32
rpoA 3878130 c.378C>G synonymous_variant 0.31
rpoA 3878141 p.Met123Leu missense_variant 0.33
rpoA 3878143 p.Gly122Asp missense_variant 0.34
rpoA 3878157 c.351C>G synonymous_variant 0.42
rpoA 3878163 c.345C>T synonymous_variant 0.42
rpoA 3878169 c.339G>C synonymous_variant 0.43
rpoA 3878172 c.336G>C synonymous_variant 0.45
rpoA 3878181 c.327C>T synonymous_variant 0.49
rpoA 3878187 c.321C>G synonymous_variant 0.49
rpoA 3878193 c.315T>C synonymous_variant 0.47
rpoA 3878199 c.309T>C synonymous_variant 0.47
rpoA 3878217 c.291A>G synonymous_variant 0.49
rpoA 3878226 c.282C>G synonymous_variant 0.51
rpoA 3878232 c.276G>C synonymous_variant 0.51
rpoA 3878247 c.261G>C synonymous_variant 0.53
rpoA 3878271 c.237T>C synonymous_variant 0.57
rpoA 3878284 p.Glu75Ala missense_variant 0.55
rpoA 3878292 c.216T>C synonymous_variant 0.55
rpoA 3878298 c.210A>G synonymous_variant 0.56
rpoA 3878304 c.204G>C synonymous_variant 0.55
rpoA 3878313 c.195G>C synonymous_variant 0.56
rpoA 3878322 c.186A>G synonymous_variant 0.55
rpoA 3878331 c.177A>G synonymous_variant 0.48
rpoA 3878334 c.174T>C synonymous_variant 0.47
rpoA 3878337 c.171T>C synonymous_variant 0.48
rpoA 3878340 c.168C>T synonymous_variant 0.5
rpoA 3878346 c.162T>C synonymous_variant 0.51
rpoA 3878364 c.144A>T synonymous_variant 0.49
rpoA 3878367 c.141C>G synonymous_variant 0.5
rpoA 3878376 c.132G>C synonymous_variant 0.51
rpoA 3878385 c.123C>G synonymous_variant 0.49
rpoA 3878388 c.120C>G synonymous_variant 0.48
rpoA 3878391 c.117T>C synonymous_variant 0.49
rpoA 3878415 c.93C>T synonymous_variant 0.43
rpoA 3878424 c.84G>C synonymous_variant 0.41
rpoA 3878436 c.72A>G synonymous_variant 0.4
rpoA 3878442 c.66G>C synonymous_variant 0.4
rpoA 3878454 c.54A>C synonymous_variant 0.37
rpoA 3878472 p.Asp12Glu missense_variant 0.37
rpoA 3878478 c.30C>G synonymous_variant 0.37
rpoA 3878484 c.24C>A synonymous_variant 0.42
rpoA 3878490 c.18C>A synonymous_variant 0.42
rpoA 3878496 c.12A>T synonymous_variant 0.38
clpC1 4038530 p.Glu725Asp missense_variant 0.29
clpC1 4038596 c.2109A>G synonymous_variant 0.43
clpC1 4038623 c.2082A>G synonymous_variant 0.52
clpC1 4038640 p.Asp689Asn missense_variant 0.55
clpC1 4038653 c.2052C>T synonymous_variant 0.56
clpC1 4038658 p.Lys683Gln missense_variant 0.53
clpC1 4038661 p.Ser682Thr missense_variant 0.53
clpC1 4038662 c.2043T>C synonymous_variant 0.51
clpC1 4038671 c.2034T>C synonymous_variant 0.55
clpC1 4038683 c.2022T>C synonymous_variant 0.55
clpC1 4038695 c.2010C>G synonymous_variant 0.54
clpC1 4038701 c.2004G>C synonymous_variant 0.52
clpC1 4038704 c.2001T>C synonymous_variant 0.51
clpC1 4038707 c.1998C>G synonymous_variant 0.52
clpC1 4038710 c.1995G>C synonymous_variant 0.52
clpC1 4038713 c.1992T>C synonymous_variant 0.54
clpC1 4038749 c.1956C>G synonymous_variant 0.58
clpC1 4038755 c.1950G>T synonymous_variant 0.56
clpC1 4038770 c.1935C>T synonymous_variant 0.58
clpC1 4038773 c.1932T>C synonymous_variant 0.58
clpC1 4038782 c.1923G>C synonymous_variant 0.57
clpC1 4038812 c.1893T>C synonymous_variant 0.6
clpC1 4038845 c.1860G>C synonymous_variant 0.59
clpC1 4038860 c.1845G>C synonymous_variant 0.61
clpC1 4038878 c.1827A>G synonymous_variant 0.61
clpC1 4038908 c.1797C>G synonymous_variant 0.6
clpC1 4038914 c.1791G>C synonymous_variant 0.59
clpC1 4038923 c.1780_1782delCTAinsTTG synonymous_variant 0.57
clpC1 4038953 c.1752A>G synonymous_variant 0.54
clpC1 4038956 c.1749T>C synonymous_variant 0.54
clpC1 4038965 c.1740T>C synonymous_variant 0.53
clpC1 4038971 c.1734T>C synonymous_variant 0.51
clpC1 4038974 c.1731T>C synonymous_variant 0.5
clpC1 4038989 c.1716T>C synonymous_variant 0.49
clpC1 4038997 c.1708T>C synonymous_variant 0.51
clpC1 4039004 c.1701C>G synonymous_variant 0.49
clpC1 4039022 c.1683A>G synonymous_variant 0.43
clpC1 4039064 c.1641C>T synonymous_variant 0.34
clpC1 4039097 c.1608G>C synonymous_variant 0.28
clpC1 4039103 c.1602T>C synonymous_variant 0.26
clpC1 4039106 c.1599G>C synonymous_variant 0.24
clpC1 4039112 c.1593C>G synonymous_variant 0.25
clpC1 4039121 c.1584T>C synonymous_variant 0.21
clpC1 4039898 c.807C>G synonymous_variant 0.28
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.3
clpC1 4039931 c.774T>C synonymous_variant 0.31
clpC1 4039937 c.768G>C synonymous_variant 0.31
clpC1 4039946 c.759A>C synonymous_variant 0.32
clpC1 4039952 c.753T>C synonymous_variant 0.32
clpC1 4039982 c.723G>A synonymous_variant 0.26
clpC1 4039988 c.717C>G synonymous_variant 0.26
clpC1 4039991 c.714G>C synonymous_variant 0.26
clpC1 4040147 c.558A>G synonymous_variant 0.22
clpC1 4040162 c.543G>C synonymous_variant 0.22
clpC1 4040165 c.540G>C synonymous_variant 0.22
clpC1 4040171 c.534C>G synonymous_variant 0.19
clpC1 4040291 c.414G>C synonymous_variant 0.2
clpC1 4040318 c.387C>G synonymous_variant 0.25
clpC1 4040330 c.375C>G synonymous_variant 0.23
clpC1 4040342 c.363C>G synonymous_variant 0.21
clpC1 4040369 c.336C>G synonymous_variant 0.19
clpC1 4040501 c.204C>T synonymous_variant 0.2
embC 4240726 c.864G>C synonymous_variant 0.47
embC 4240780 c.918T>C synonymous_variant 0.5
embC 4240781 p.Ala307Ser missense_variant 0.5
embC 4240789 c.927T>C synonymous_variant 0.53
embC 4240819 c.957A>G synonymous_variant 0.58
embC 4240828 c.966G>A synonymous_variant 0.59
embC 4240831 c.969T>G synonymous_variant 0.55
embC 4240867 c.1005T>C synonymous_variant 0.45
embC 4240870 c.1008T>C synonymous_variant 0.45
embC 4240873 c.1011C>G synonymous_variant 0.45
embC 4240879 c.1017G>C synonymous_variant 0.39
embC 4240880 p.Ala340Thr missense_variant 0.38
embC 4240885 c.1023T>C synonymous_variant 0.37
embC 4240897 c.1035C>G synonymous_variant 0.32
embC 4240898 c.1036_1038delCTAinsTTG synonymous_variant 0.32
embC 4240903 c.1041C>G synonymous_variant 0.32
embC 4240911 p.Ala350Val missense_variant 0.33
embC 4240921 c.1059C>G synonymous_variant 0.35
embC 4240924 c.1062C>G synonymous_variant 0.31
embC 4240936 c.1074A>G synonymous_variant 0.23
embC 4240996 c.1134G>C synonymous_variant 0.21
embC 4241002 c.1140G>C synonymous_variant 0.24
embC 4241013 p.Met384Thr missense_variant 0.25
embC 4241017 c.1155T>C synonymous_variant 0.33
embC 4241023 c.1161T>G synonymous_variant 0.42
embC 4241032 c.1170G>C synonymous_variant 0.45
embC 4241038 c.1176G>C synonymous_variant 0.45
embC 4241047 c.1185C>G synonymous_variant 0.62
embC 4241050 c.1188T>G synonymous_variant 0.71
embC 4241053 c.1191G>A synonymous_variant 0.82
embC 4241089 c.1227C>G synonymous_variant 1.0
embC 4241095 c.1233C>T synonymous_variant 1.0
embC 4241158 c.1296T>C synonymous_variant 0.43
embA 4242748 c.-485A>G upstream_gene_variant 0.22
embA 4242754 c.-479G>C upstream_gene_variant 0.19
embC 4242764 p.Val968Leu missense_variant 0.24
embC 4242779 p.Asn973Asp missense_variant 0.2
embA 4243460 c.228C>T synonymous_variant 1.0
embA 4244582 c.1350T>C synonymous_variant 0.55
embA 4245198 p.Leu656Ile missense_variant 0.21
embA 4245207 c.1975T>C synonymous_variant 0.19
embB 4246088 c.-426A>G upstream_gene_variant 0.2
embB 4246097 c.-417C>G upstream_gene_variant 0.2
embB 4246103 c.-411C>G upstream_gene_variant 0.2
embB 4246109 c.-405C>A upstream_gene_variant 0.2
embB 4246115 c.-399T>G upstream_gene_variant 0.2
embB 4246130 c.-384T>C upstream_gene_variant 0.21
embA 4246138 p.Arg969Gln missense_variant 0.21
embB 4246140 c.-374T>C upstream_gene_variant 0.21
embA 4246143 p.Ile971Val missense_variant 0.21
embB 4246157 c.-357A>G upstream_gene_variant 0.21
embB 4246164 c.-350T>C upstream_gene_variant 0.21
embB 4246184 c.-330A>C upstream_gene_variant 0.22
embB 4246196 c.-318C>G upstream_gene_variant 0.22
embB 4246205 c.-309A>G upstream_gene_variant 0.19
embB 4246211 c.-303T>C upstream_gene_variant 0.2
embB 4247386 c.873T>C synonymous_variant 0.21
embB 4247395 c.882C>G synonymous_variant 0.25
embB 4247401 c.888T>C synonymous_variant 0.27
embB 4247407 c.894G>C synonymous_variant 0.28
embB 4247425 c.912G>C synonymous_variant 0.33
embB 4247434 c.921C>G synonymous_variant 0.35
embB 4247437 c.924A>G synonymous_variant 0.35
embB 4247440 c.927C>G synonymous_variant 0.36
embB 4247446 c.933C>T synonymous_variant 0.34
embB 4247464 c.951C>G synonymous_variant 0.41
embB 4247470 c.957T>C synonymous_variant 0.4
embB 4247491 c.978G>C synonymous_variant 0.45
embB 4247497 c.984T>C synonymous_variant 0.48
embB 4247512 c.999T>C synonymous_variant 0.53
embB 4247539 c.1026T>C synonymous_variant 0.54
embB 4247554 c.1041T>C synonymous_variant 0.54
embB 4247566 c.1053C>A synonymous_variant 0.5
embB 4247572 c.1059A>G synonymous_variant 0.51
embB 4247579 p.Ala356Phe missense_variant 0.54
embB 4247587 c.1074G>A synonymous_variant 0.53
embB 4247603 c.1090C>T synonymous_variant 0.6
embB 4247611 c.1098G>T synonymous_variant 0.56
embB 4247614 c.1101T>C synonymous_variant 0.58
embB 4247629 c.1116C>G synonymous_variant 0.59
embB 4247761 c.1248T>C synonymous_variant 0.24
embB 4247767 c.1254G>A synonymous_variant 0.26
embB 4247773 c.1260G>A synonymous_variant 0.26
embB 4247776 c.1263G>T synonymous_variant 0.27
embB 4247797 c.1284C>G synonymous_variant 0.33
embB 4247800 c.1287A>T synonymous_variant 0.35
embB 4248007 c.1494C>G synonymous_variant 0.28
embB 4248011 p.Ser500Arg missense_variant 0.23
embB 4248014 p.Thr501Ala missense_variant 0.22
embB 4248027 p.Ala505Asp missense_variant 0.67
embB 4248035 p.Val508Ile missense_variant 0.32
embB 4248040 c.1527C>G synonymous_variant 0.31
embB 4248041 p.Ala510Thr missense_variant 0.32
embB 4248044 p.Lys511Ala missense_variant 0.33
embB 4248070 c.1557T>C synonymous_variant 0.32
embB 4248085 c.1572T>C synonymous_variant 0.34
embB 4248097 c.1584C>G synonymous_variant 0.36
embB 4248130 c.1617G>C synonymous_variant 0.37
embB 4248142 c.1629T>C synonymous_variant 0.33
embB 4248143 c.1630T>C synonymous_variant 0.34
embB 4248157 c.1644A>G synonymous_variant 0.35
embB 4248172 c.1659G>C synonymous_variant 0.36
embB 4248199 c.1686A>G synonymous_variant 0.33
embB 4248200 p.Ile563Val missense_variant 0.33
embB 4248205 c.1692C>G synonymous_variant 0.31
embB 4248206 p.Ser565Gly missense_variant 0.32
embB 4248220 c.1707A>C synonymous_variant 0.35
embB 4249498 c.2985G>C synonymous_variant 0.24
embB 4249521 p.Ala1003Val missense_variant 0.28
embB 4249525 c.3012T>C synonymous_variant 0.28
embB 4249529 p.Ile1006Val missense_variant 0.27
embB 4249532 p.Ala1007Thr missense_variant 0.28
embB 4249537 c.3024A>G synonymous_variant 0.28
embB 4249543 c.3030G>C synonymous_variant 0.29
embB 4249546 c.3033G>A synonymous_variant 0.29
embB 4249558 c.3045A>C synonymous_variant 0.28
embB 4249568 p.Ser1019Thr missense_variant 0.29
embB 4249573 c.3060T>C synonymous_variant 0.28
embB 4249580 p.Leu1023Met missense_variant 0.26
embB 4249594 c.3081G>C synonymous_variant 0.29
embB 4249606 c.3093C>A synonymous_variant 0.24
embB 4249609 c.3096T>C synonymous_variant 0.22
aftB 4267241 c.1596G>C synonymous_variant 0.22
aftB 4267244 c.1593T>C synonymous_variant 0.23
aftB 4267256 c.1581C>G synonymous_variant 0.24
aftB 4267262 c.1575T>C synonymous_variant 0.26
aftB 4267266 p.Ala524Gly missense_variant 0.25
aftB 4267268 c.1569T>C synonymous_variant 0.25
aftB 4267274 c.1563G>C synonymous_variant 0.25
aftB 4267289 p.Ala516Gln missense_variant 0.25
aftB 4267292 c.1545C>G synonymous_variant 0.24
aftB 4267297 c.1540T>C synonymous_variant 0.23
aftB 4267301 c.1536C>T synonymous_variant 0.22
aftB 4267304 p.Val511Ala missense_variant 0.22
aftB 4267316 c.1521A>G synonymous_variant 0.23
aftB 4267325 c.1512G>C synonymous_variant 0.25
aftB 4267334 c.1503T>C synonymous_variant 0.25
aftB 4267647 p.Asp397Gly missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 0.99