Run ID: ERR1035157
Sample name:
Date: 2024-10-05T03:00:29.447114
Number of reads: 201973
Percentage reads mapped: 13.81
Median coverage: 3.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|---|---|---|
La1.2.BCG | M.bovis | None | 0.07 |
lineage4 | Euro-American | None | 0.97 |
lineage4.9 | Euro-American (H37Rv-like) | None | 0.98 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | ||||
pyrazinamide | ||||
streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 1068 | c.1068T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1092 | c.1092T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 1098 | c.1098A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1428 | c.1428C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1449 | c.1449G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1461 | c.1461C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1470 | c.1470C>T | synonymous_variant | 1.0 | isoniazid | |
gyrB | 5824 | c.585A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5827 | c.588G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5849 | c.610C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5854 | c.615C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5863 | c.624G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5873 | c.634A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6238 | c.999G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6268 | c.1029C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 6346 | c.1107C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6577 | c.1338T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6598 | c.-704C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6610 | c.-692C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6613 | c.-689A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6616 | c.-686A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6622 | c.-680C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6634 | c.-668T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6637 | c.-665T>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6640 | c.-662A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6808 | c.1569C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6811 | c.1572C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6841 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6844 | c.-458T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6853 | c.-449A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6856 | c.1617T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6859 | c.1620T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6862 | c.1623C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7033 | c.-269G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7165 | c.-137C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7178 | c.-124T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7186 | c.1947C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 7216 | c.1977G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7228 | c.-74C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7234 | c.1995C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7361 | c.60C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7391 | c.90C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7394 | c.93T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7475 | c.174A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7532 | c.231T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7694 | c.393A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7697 | c.396C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7739 | c.438C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7763 | c.462T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7823 | c.522G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7832 | c.531G>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7835 | c.534A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7853 | c.552C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7859 | c.558A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7865 | c.564T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8156 | c.855T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8168 | c.867A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8189 | c.888G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8198 | c.897T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8528 | c.1227G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8543 | c.1242C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8553 | c.1252C>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8564 | c.1263G>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8588 | c.1287G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8603 | c.1302A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8624 | c.1323G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8678 | c.1377G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8852 | c.1551T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8858 | c.1557T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8867 | c.1566A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8891 | c.1590G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8933 | c.1632G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCTC | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9182 | c.1881T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9191 | c.1890G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9204 | p.Ser635Thr | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9224 | c.1923C>T | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9233 | c.1932C>G | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9239 | c.1938C>T | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9252 | p.Val651Ile | missense_variant | 0.95 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 0.9 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9308 | p.Asp669Glu | missense_variant | 0.9 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9323 | c.2022C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9335 | c.2034G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9344 | c.2043C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9365 | c.2064G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9374 | c.2073G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9377 | c.2076A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9383 | c.2082T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9386 | c.2085T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
mshA | 575779 | c.432A>G | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
mshA | 575782 | c.435G>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
mshA | 575812 | c.465C>T | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
mshA | 575830 | c.483C>G | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
ccsA | 619609 | c.-282G>C | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619634 | c.-257T>A | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619645 | c.-246G>C | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 619654 | c.-237A>G | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 1.0 | ethionamide | |
Rv0565c | 657261 | c.210C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657264 | c.207T>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657267 | c.204G>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657678 | c.-209_-208delAAinsTC | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAC | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 1.0 | ethionamide | |
hadA | 731732 | c.-198G>A | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731747 | c.-183T>C | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731774 | c.-156T>C | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731789 | c.-141A>G | upstream_gene_variant | 0.94 | isoniazid | |
hadA | 731792 | c.-138G>A | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731801 | c.-129C>G | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731816 | c.-114G>A | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 732295 | c.366G>C | synonymous_variant | 1.0 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 1.0 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 1.0 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 1.0 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 1.0 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 1.0 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 1.0 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 1.0 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 1.0 | isoniazid | |
nusG | 734407 | p.Val52Ile | missense_variant | 1.0 | rifampicin | |
nusG | 734421 | c.168A>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734556 | c.303C>T | synonymous_variant | 1.0 | rifampicin | |
nusG | 734559 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734589 | c.336G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734882 | p.Ala210Gly | missense_variant | 1.0 | rifampicin | |
rpoB | 760091 | c.285G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760101 | c.295T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760112 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760118 | c.312T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760310 | c.504G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 1.0 | rifampicin | |
rpoB | 760406 | c.600G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760412 | c.606C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760424 | c.618C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760718 | c.912C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760724 | c.918T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760925 | c.1119T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760934 | c.1128C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760982 | c.1176G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761006 | c.1200C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761129 | c.1323G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761132 | c.1326G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761153 | c.1347G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761165 | c.1359G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761207 | c.1401C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761213 | c.1407G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761219 | c.1413G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761306 | c.1500C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761312 | c.1506G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761330 | c.1524G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761354 | c.1548C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761360 | c.1554T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 1.0 | rifampicin | |
rpoB | 761373 | p.Val523His | missense_variant | 1.0 | rifampicin | |
rpoB | 761510 | c.1704T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761588 | c.1782C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761675 | c.1869G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761815 | p.Ala670Glu | missense_variant | 1.0 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762008 | c.2202C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762014 | c.2208C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762206 | c.2400C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762233 | c.2427G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762246 | c.2440C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762254 | c.2448T>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762314 | c.2508C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762419 | c.-951C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762449 | c.2643C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762467 | c.-903C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762521 | c.-849C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762551 | c.-819C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762860 | c.3054G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763013 | c.-357C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 763028 | c.3222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763136 | c.3330C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763190 | c.-180C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763402 | c.33C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763411 | c.42T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763441 | c.72C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763774 | c.405G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763816 | c.447C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 1.0 | rifampicin | |
rpoC | 763853 | p.Val162Ile | missense_variant | 1.0 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763900 | c.531G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764140 | c.771C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Ile | missense_variant | 1.0 | rifampicin | |
rpoC | 764203 | c.834G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764215 | c.846A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764338 | c.969G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764428 | c.1059G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764489 | c.1120C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764510 | c.1141C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764554 | c.1185C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764692 | c.1323C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764705 | c.1336C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764908 | c.1539G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764911 | c.1542A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764932 | c.1563C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764935 | c.1566T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764948 | c.1579T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765346 | c.1977C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765349 | c.1980T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765352 | c.1983G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765383 | p.Met672Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 1.0 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765529 | c.2160C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765580 | c.2211G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 1.0 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765751 | c.2382C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765850 | c.2481G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765937 | c.2568T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765982 | c.2613C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766030 | c.2661C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766036 | c.2667C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 1.0 | rifampicin | |
rpoC | 766054 | c.2685C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 766096 | c.2727G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766135 | c.2766G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766141 | c.2772C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766142 | c.2773C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766303 | c.2934C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766312 | c.2943T>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766327 | c.2958C>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766345 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766357 | c.2988C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766363 | c.2994G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766366 | c.2997C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766393 | c.3024C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766408 | c.3039C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766411 | c.3042C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766426 | c.3057C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766462 | c.3093G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766484 | p.Val1039Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766500 | p.Ala1044Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 766522 | c.3153C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766531 | c.3162G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766540 | p.Asp1057Glu | missense_variant | 1.0 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766630 | c.3261G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766673 | p.Gly1102Asn | missense_variant | 1.0 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766777 | c.3408C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766801 | c.3432C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766876 | c.3507C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766882 | c.3513C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766894 | c.3525T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766933 | c.3564A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767014 | c.3645G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767068 | c.3699G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767158 | c.3789T>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpsL | 781628 | c.69T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
rpsL | 781631 | c.72G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781742 | c.183C>T | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781748 | c.189C>G | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781772 | c.213C>A | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781877 | c.318T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
rplC | 800516 | c.-293G>T | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800537 | c.-272C>T | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800540 | c.-269T>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800546 | c.-263T>G | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800627 | c.-182C>T | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800648 | c.-161A>T | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800794 | c.-15A>G | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 1.0 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 1.0 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801339 | c.531T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801341 | p.Leu178Gln | missense_variant | 1.0 | linezolid | |
rplC | 801348 | c.540T>G | synonymous_variant | 1.0 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801367 | p.Ala187Thr | missense_variant | 1.0 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 1.0 | linezolid | |
fbiC | 1303545 | c.615A>G | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303602 | c.672A>G | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303605 | c.675C>G | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303608 | c.678G>A | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303614 | c.684C>T | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303617 | c.687C>G | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303797 | c.867A>G | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303971 | c.1041T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303980 | c.1050G>A | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304004 | c.1074A>G | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304008 | c.1078T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304106 | c.1176G>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304568 | c.1638T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304613 | c.1683T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304634 | c.1704C>G | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304787 | c.1857T>G | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304832 | c.1902C>T | synonymous_variant | 1.0 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304862 | c.1932G>A | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304869 | c.1939C>T | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.9 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304955 | c.2025G>A | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304983 | c.2053C>T | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304995 | p.Leu689Met | missense_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305006 | c.2076A>G | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305012 | c.2082G>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305015 | c.2085G>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305372 | c.2442G>A | synonymous_variant | 1.0 | pretomanid | |
delamanid | ||||||
clofazimine | Not assoc w R - Interim | |||||
atpE | 1461170 | c.126A>G | synonymous_variant | 1.0 | bedaquiline | |
atpE | 1461185 | c.141G>C | synonymous_variant | 1.0 | bedaquiline | |
atpE | 1461194 | c.150C>T | synonymous_variant | 1.0 | bedaquiline | |
atpE | 1461197 | c.153A>G | synonymous_variant | 1.0 | bedaquiline | |
atpE | 1461219 | c.175T>C | synonymous_variant | 1.0 | bedaquiline | |
atpE | 1461233 | c.189A>C | synonymous_variant | 1.0 | bedaquiline | |
rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrl | 1473668 | n.11C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.93 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473832 | n.175C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1473987 | n.330G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474093 | n.436G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474099 | n.442G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
linezolid | ||||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474904 | n.1247G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474956 | n.1299C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474960 | n.1303C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474963 | n.1306G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474964 | n.1307T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474965 | n.1308G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474970 | n.1313G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475006 | n.1349A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475206 | n.1549C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475209 | n.1552G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475249 | n.1592T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475252 | n.1595C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475266 | n.1609T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475267 | n.1610G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475275 | n.1618C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475276 | n.1619T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475313 | n.1656G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475436 | n.1779C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475761 | n.2104_2106delCGCinsGT | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476031 | n.2374C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476032 | n.2375C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476034 | n.2377C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476048 | n.2391G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
inhA | 1673657 | c.-545C>A | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1673660 | c.-542C>A | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1673664 | c.-538A>C | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1673667 | c.-535A>G | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1673679 | c.-523T>C | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
ethionamide | Uncertain significance | |||||
inhA | 1673685 | c.-517C>T | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1673710 | c.-492C>A | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1673716 | c.-486_-485delGCinsAA | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1673733 | c.-469G>C | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1673901 | c.-301A>G | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1673905 | c.-297T>G | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1673916 | c.-286A>C | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1673917 | c.-285G>C | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1673922 | c.-280T>C | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1673941 | c.-261G>T | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1673955 | c.-247G>C | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1673961 | c.-241A>C | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1673985 | c.-217C>G | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674105 | c.-97C>T | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674114 | c.-88T>A | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
ethionamide | Uncertain significance | |||||
inhA | 1674123 | c.-79T>C | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674126 | c.-76G>C | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674132 | c.-70T>C | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674136 | c.-66T>G | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674141 | c.-61T>C | upstream_gene_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674177 | c.-25C>T | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
ethionamide | Uncertain significance | |||||
inhA | 1674486 | c.285T>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674504 | c.303C>G | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674507 | c.306G>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674537 | c.336C>G | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674546 | c.345T>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674549 | c.348G>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674555 | c.354G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674561 | c.360C>T | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674582 | c.381T>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674585 | c.384T>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674589 | p.Met130Leu | missense_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674601 | p.Leu134Thr | missense_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674624 | c.423A>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674660 | c.459G>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674672 | c.471C>G | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674708 | c.507G>A | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674718 | c.517A>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674846 | p.Ile215Met | missense_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674870 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674879 | c.678T>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674888 | c.687C>G | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674903 | c.702T>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674904 | p.Ala235Pro | missense_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674942 | c.741T>G | synonymous_variant | 0.94 | isoniazid | |
ethionamide | ||||||
inhA | 1674954 | c.753G>C | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
inhA | 1674960 | c.759C>G | synonymous_variant | 1.0 | isoniazid | |
ethionamide | ||||||
rpsA | 1833554 | p.Thr5Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
rpsA | 1833568 | c.27G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833721 | c.180A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833748 | c.207C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833971 | c.430C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834303 | c.762T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834333 | c.792C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834396 | c.855G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834618 | c.1077G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834654 | p.Glu371Asp | missense_variant | 1.0 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834732 | c.1191T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Ser | missense_variant | 1.0 | pyrazinamide | |
rpsA | 1834738 | c.1197A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834765 | p.Glu408Asp | missense_variant | 1.0 | pyrazinamide | |
rpsA | 1834775 | p.Ala412Thr | missense_variant | 1.0 | pyrazinamide | |
rpsA | 1834780 | c.1239A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834792 | c.1251G>C | synonymous_variant | 1.0 | pyrazinamide | |
ndh | 2101783 | c.1260T>G | synonymous_variant | 1.0 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101960 | c.1083A>G | synonymous_variant | 1.0 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101963 | c.1080G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
delamanid | Not assoc w R - Interim | |||||
ethionamide | Not assoc w R - Interim | |||||
ndh | 2101966 | c.1077T>G | synonymous_variant | 1.0 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101972 | c.1071G>C | synonymous_variant | 1.0 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101988 | p.Ala352Asp | missense_variant | 1.0 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101990 | c.1053G>C | synonymous_variant | 1.0 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2101993 | c.1050A>G | synonymous_variant | 1.0 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102014 | c.1029C>G | synonymous_variant | 1.0 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102644 | c.399A>G | synonymous_variant | 1.0 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102671 | c.372T>G | synonymous_variant | 1.0 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102680 | c.363T>G | synonymous_variant | 1.0 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
ndh | 2102683 | c.360T>C | synonymous_variant | 1.0 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
pncA | 2289925 | c.-684T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
pncA | 2289930 | c.-689A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
pncA | 2289943 | c.-702T>G | upstream_gene_variant | 1.0 | pyrazinamide | |
pncA | 2289948 | c.-707C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
pncA | 2289949 | c.-708A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
pncA | 2289987 | c.-746C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 1.0 | isoniazid | |
kasA | 2517989 | c.-126T>C | upstream_gene_variant | 1.0 | isoniazid | |
kasA | 2517993 | c.-122G>T | upstream_gene_variant | 1.0 | isoniazid | |
kasA | 2518162 | c.48G>A | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518174 | c.60A>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518190 | p.Ser26Ala | missense_variant | 1.0 | isoniazid | |
kasA | 2518199 | p.Ile29Val | missense_variant | 1.0 | isoniazid | |
kasA | 2518220 | c.106C>T | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518504 | c.390T>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518506 | p.Ala131Glu | missense_variant | 1.0 | isoniazid | |
kasA | 2518519 | c.405G>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518528 | c.414C>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518540 | c.426T>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518561 | c.447T>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518567 | c.453G>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518603 | c.489G>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518732 | c.618C>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518768 | c.654C>T | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518777 | c.663C>T | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518789 | c.675G>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518792 | c.678C>A | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518879 | c.765A>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518885 | c.771T>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518898 | c.784T>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2519107 | c.993T>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2519122 | c.1008G>C | synonymous_variant | 1.0 | isoniazid | |
kasA | 2519137 | c.1023T>G | synonymous_variant | 1.0 | isoniazid | |
kasA | 2519158 | c.1044C>T | synonymous_variant | 1.0 | isoniazid | |
kasA | 2519167 | c.1053T>G | synonymous_variant | 1.0 | isoniazid | |
ahpC | 2726638 | p.Ala149Val | missense_variant | 1.0 | isoniazid | |
ahpC | 2726645 | c.453C>G | synonymous_variant | 1.0 | isoniazid | |
ahpC | 2726657 | c.465A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
ahpC | 2726681 | c.489A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
Rv2477c | 2782450 | c.1593C>A | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782453 | c.1590C>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782483 | c.1560G>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782936 | c.1107G>T | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2782948 | c.1095A>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783146 | c.897G>A | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783149 | c.894G>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783158 | c.885A>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783179 | c.864G>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783182 | c.861C>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783185 | c.858G>A | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783194 | c.849A>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783221 | c.822G>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783224 | c.819C>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783230 | c.813T>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783395 | c.648T>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783656 | c.387G>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783718 | c.325T>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783914 | c.129T>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783920 | c.123G>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783929 | c.114C>G | synonymous_variant | 0.94 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783932 | c.111C>T | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783938 | c.105T>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783953 | c.90G>A | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783962 | c.81T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
levofloxacin | ||||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783971 | c.72G>C | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783980 | c.63C>G | synonymous_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783992 | c.51T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2784472 | c.-430C>A | upstream_gene_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2784477 | c.-435T>C | upstream_gene_variant | 1.0 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2752c | 3065007 | c.1185G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065013 | c.1179G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065018 | p.Asn392His | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065019 | c.1173C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065022 | c.1170G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065028 | c.1164G>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066549 | c.-358T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066561 | c.-370A>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066567 | c.-376C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066573 | c.-382G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066579 | c.-388A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066583 | c.-392C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066780 | c.-589C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
thyX | 3067439 | c.507A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067442 | c.504C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067445 | c.501C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067457 | c.489C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067465 | p.Ile161Val | missense_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067475 | c.471A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067490 | c.456C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067493 | c.453A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067515 | p.Ser144Thr | missense_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067530 | p.Ala139Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067545 | p.Glu134Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067611 | p.Lys112Thr | missense_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067619 | c.327A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067631 | c.315C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067634 | c.312C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067652 | c.294T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067661 | c.285C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067685 | c.261A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067691 | p.Ile85Leu | missense_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067694 | c.252G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067739 | c.207T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067772 | c.174C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067781 | c.165C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067793 | c.153T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067799 | c.147G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067802 | c.144C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067814 | c.132T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyX | 3067850 | c.96A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3073887 | c.585G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3073892 | c.580T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3073898 | p.Ala192Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3073917 | c.555C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3073920 | c.552C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3073925 | c.547T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3073929 | c.543T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3074205 | p.Glu89Asp | missense_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3074214 | c.258T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
lpqB | 3624749 | c.162G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3624755 | c.154_156delTTAinsCTG | synonymous_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625195 | c.-285A>G | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625201 | c.-291T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625569 | c.1045T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625572 | p.Thr348Ser | missense_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625616 | p.Arg333Ala | missense_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625633 | c.981C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625636 | c.978C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625656 | c.958T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625749 | c.-839C>T | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625750 | c.864G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
bedaquiline | ||||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625774 | c.840G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625797 | p.Val273Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625807 | c.807C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625837 | c.777C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625852 | c.762A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 0.94 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625876 | c.738G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626124 | p.Ala164Ser | missense_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626125 | c.489C>G | synonymous_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626711 | c.-98T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626723 | c.627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627098 | c.252A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627119 | c.231T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627188 | c.162A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627221 | c.129C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627227 | c.123T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627242 | c.108C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627299 | c.-688_-686delTTGinsCTA | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627314 | c.-701C>T | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627343 | p.Thr3Ser | missense_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627360 | c.-747G>C | upstream_gene_variant | 1.0 | rifampicin | |
bedaquiline | ||||||
rpoA | 3877507 | p.Gly334Ala | missense_variant | 1.0 | rifampicin | |
rpoA | 3877515 | c.993G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877553 | p.Glu319Gln | missense_variant | 1.0 | rifampicin | |
rpoA | 3877571 | p.Pro313Ala | missense_variant | 0.92 | rifampicin | |
rpoA | 3877587 | c.921A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877613 | p.Ile299Val | missense_variant | 1.0 | rifampicin | |
rpoA | 3877617 | c.891G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877656 | c.852T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877668 | c.840A>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877679 | p.Ala277Ser | missense_variant | 1.0 | rifampicin | |
rpoA | 3877686 | c.822A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877737 | c.771G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877743 | c.765T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877764 | c.744C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877791 | c.717C>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877818 | c.690A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877824 | c.684G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3877962 | c.546G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877986 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3877989 | c.519A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878001 | c.507A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878022 | c.486T>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878040 | c.468T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878193 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878199 | c.309T>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878226 | c.282C>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878232 | c.276G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878247 | c.261G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878271 | c.237T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878284 | p.Glu75Ala | missense_variant | 1.0 | rifampicin | |
rpoA | 3878292 | c.216T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878298 | c.210A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878304 | c.204G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878310 | c.198G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878322 | c.186A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878331 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878334 | c.174T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoA | 3878346 | c.162T>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878352 | c.156C>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878364 | c.144A>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878367 | c.141C>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878376 | c.132G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878385 | c.123C>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878388 | c.120C>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878415 | c.93C>T | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878424 | c.84G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878436 | c.72A>G | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878442 | c.66G>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878454 | c.54A>C | synonymous_variant | 1.0 | rifampicin | |
rpoA | 3878761 | c.-254G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878785 | c.-278T>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878938 | c.-431T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoA | 3878976 | c.-469A>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoA | 3879005 | c.-499_-498delAAinsCG | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879178 | c.-671T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoA | 3879190 | c.-683C>G | upstream_gene_variant | 1.0 | rifampicin | |
clpC1 | 4038392 | c.2313C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038640 | p.Asp689Asn | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038653 | c.2052C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038658 | p.Lys683Gln | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038661 | p.Ser682Thr | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4038662 | c.2043T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038671 | c.2034T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038683 | c.2022T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038845 | c.1860G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038857 | c.1848C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038860 | c.1845G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038923 | c.1780_1782delCTAinsTTG | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039004 | c.1701C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039064 | c.1641C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4039172 | c.1533A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039183 | c.1522T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039186 | c.1519C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039226 | c.1479T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039274 | c.1431G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039364 | c.1341C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039391 | c.1314T>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039409 | c.1296T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039412 | c.1293T>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039415 | p.Glu430Asp | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
clpC1 | 4039430 | c.1275T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039442 | c.1263A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039454 | c.1251A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039463 | c.1242C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039466 | c.1239T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039469 | c.1236T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039480 | c.1225C>A | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039481 | c.1224T>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039517 | c.1188C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039556 | c.1149G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039559 | c.1146C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039562 | c.1143C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039565 | c.1140G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039570 | p.Met379Leu | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
clpC1 | 4039576 | p.Ala377Pro | missense_variant | 1.0 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039589 | c.1116G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039622 | c.1083C>T | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039661 | c.1044T>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039664 | c.1041G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.92 | pyrazinamide | |
clpC1 | 4039790 | c.915C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039817 | c.888A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039820 | c.885T>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039826 | c.879C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039831 | c.874T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.92 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4039991 | c.714G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040036 | c.669C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040093 | c.612C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040147 | c.558A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040162 | c.543G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040165 | c.540G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040171 | c.534C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040330 | c.375C>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040465 | c.240T>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040471 | c.234T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040477 | c.228G>C | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040480 | c.225T>G | synonymous_variant | 1.0 | pyrazinamide | |
clpC1 | 4040522 | c.183T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
glpK | 4138757 | c.999A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138763 | c.993G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138769 | c.987G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139165 | p.Val197Ala | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139168 | c.588T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139177 | c.579T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139183 | c.573T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139186 | c.570G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4139195 | c.561G>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4139198 | c.558C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4139207 | c.549T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139597 | c.159C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139601 | p.Arg52Gln | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139615 | c.141G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | ||||||
glpK | 4139651 | p.His35Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
embC | 4239336 | c.-527T>C | upstream_gene_variant | 1.0 | ethambutol | |
embC | 4239341 | c.-522G>C | upstream_gene_variant | 1.0 | ethambutol | |
embC | 4239344 | c.-519G>C | upstream_gene_variant | 1.0 | ethambutol | |
embC | 4240669 | c.807G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240671 | p.Thr270Ile | missense_variant | 1.0 | ethambutol | Not assoc w R |
embC | 4240677 | p.Gly272Ala | missense_variant | 1.0 | ethambutol | |
embC | 4240685 | p.Thr275Ala | missense_variant | 1.0 | ethambutol | |
embC | 4240693 | c.831T>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4240699 | c.837C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embC | 4240726 | c.864G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embC | 4240780 | c.918T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240783 | c.921G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240789 | c.927T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240819 | c.957A>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4240867 | c.1005T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4240870 | c.1008T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241089 | c.1227C>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4241095 | c.1233C>T | synonymous_variant | 1.0 | ethambutol | |
embC | 4241107 | c.1245G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241140 | c.1278A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embC | 4241146 | c.1284C>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4241158 | c.1296T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241161 | c.1299C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embC | 4241162 | c.1300T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241170 | c.1308G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241173 | c.1311C>T | synonymous_variant | 1.0 | ethambutol | |
embC | 4241218 | c.1356G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241224 | c.1362G>A | synonymous_variant | 1.0 | ethambutol | |
embC | 4241479 | c.1617C>G | synonymous_variant | 1.0 | ethambutol | |
embC | 4241480 | c.1618T>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241488 | c.1626G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241496 | p.Ala545Gly | missense_variant | 1.0 | ethambutol | |
embC | 4241591 | p.Leu577Val | missense_variant | 1.0 | ethambutol | |
embC | 4241611 | c.1749G>C | synonymous_variant | 1.0 | ethambutol | |
embC | 4241626 | c.1764T>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4242742 | c.-491C>G | upstream_gene_variant | 1.0 | ethambutol | |
embA | 4242748 | c.-485A>G | upstream_gene_variant | 1.0 | ethambutol | |
embA | 4242754 | c.-479G>C | upstream_gene_variant | 1.0 | ethambutol | |
embC | 4242764 | p.Val968Leu | missense_variant | 1.0 | ethambutol | |
embC | 4242779 | p.Asn973Asp | missense_variant | 1.0 | ethambutol | |
embC | 4242791 | p.Ala977Ser | missense_variant | 1.0 | ethambutol | |
embA | 4242796 | c.-437G>C | upstream_gene_variant | 1.0 | ethambutol | |
embA | 4242799 | c.-434T>C | upstream_gene_variant | 1.0 | ethambutol | |
embA | 4242820 | c.-413G>C | upstream_gene_variant | 1.0 | ethambutol | |
embA | 4245060 | c.1828T>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4245083 | c.1851A>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4245089 | c.1857G>C | synonymous_variant | 0.89 | ethambutol | |
embA | 4245092 | c.1860C>G | synonymous_variant | 1.0 | ethambutol | |
embA | 4245101 | c.1869G>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4245137 | c.1905T>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4245146 | c.1914G>A | synonymous_variant | 1.0 | ethambutol | |
embA | 4245149 | c.1917C>G | synonymous_variant | 1.0 | ethambutol | |
embA | 4245153 | p.Ile641Val | missense_variant | 1.0 | ethambutol | |
embA | 4245182 | c.1950T>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4245189 | c.1957C>T | synonymous_variant | 1.0 | ethambutol | |
embA | 4245198 | p.Leu656Ile | missense_variant | 1.0 | ethambutol | |
embA | 4245207 | c.1975T>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4245215 | c.1983A>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4245222 | p.Tyr664Gln | missense_variant | 1.0 | ethambutol | |
embA | 4245248 | c.2016G>C | synonymous_variant | 1.0 | ethambutol | |
embA | 4245257 | c.2025A>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4245725 | c.-789A>G | upstream_gene_variant | 1.0 | ethambutol | |
embB | 4245726 | c.-788T>C | upstream_gene_variant | 1.0 | ethambutol | |
embB | 4245737 | c.-777A>C | upstream_gene_variant | 1.0 | ethambutol | |
embB | 4245740 | c.-774T>C | upstream_gene_variant | 1.0 | ethambutol | |
embB | 4246292 | c.-222A>G | upstream_gene_variant | 1.0 | ethambutol | |
embB | 4246316 | c.-198T>G | upstream_gene_variant | 1.0 | ethambutol | |
embB | 4246319 | c.-195G>C | upstream_gene_variant | 1.0 | ethambutol | |
embB | 4247464 | c.951C>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4247470 | c.957T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247491 | c.978G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247497 | c.984T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247512 | c.999T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247539 | c.1026T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247554 | c.1041T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247566 | c.1053C>A | synonymous_variant | 1.0 | ethambutol | |
embB | 4247572 | c.1059A>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4247866 | c.1353G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247876 | c.1363C>T | synonymous_variant | 1.0 | ethambutol | |
embB | 4247881 | c.1368G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247887 | c.1374C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embB | 4247893 | c.1380C>T | synonymous_variant | 1.0 | ethambutol | |
embB | 4247899 | p.Met462Ile | missense_variant | 1.0 | ethambutol | |
embB | 4247905 | c.1392G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embB | 4247909 | c.1396T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247932 | c.1419C>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4247940 | p.Leu476Trp | missense_variant | 1.0 | ethambutol | |
embB | 4247945 | c.1432T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4247951 | p.Ser480Ala | missense_variant | 1.0 | ethambutol | |
embB | 4247956 | c.1443G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
embB | 4247974 | c.1461C>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4248007 | c.1494C>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4248011 | p.Ser500Arg | missense_variant | 1.0 | ethambutol | |
embB | 4248014 | p.Thr501Ala | missense_variant | 1.0 | ethambutol | Uncertain significance |
embB | 4248035 | p.Val508Ile | missense_variant | 1.0 | ethambutol | |
embB | 4248040 | c.1527C>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4248041 | p.Ala510Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
embB | 4248044 | p.Lys511Ala | missense_variant | 1.0 | ethambutol | |
embB | 4248070 | c.1557T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4248085 | c.1572T>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4248097 | c.1584C>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4248199 | c.1686A>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4248200 | p.Ile563Val | missense_variant | 1.0 | ethambutol | |
embB | 4248205 | c.1692C>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4248206 | p.Ser565Gly | missense_variant | 1.0 | ethambutol | Uncertain significance |
embB | 4248220 | c.1707A>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4248304 | c.1791G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4248319 | c.1806A>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4248343 | c.1830G>C | synonymous_variant | 1.0 | ethambutol | |
embB | 4248386 | c.1873C>A | synonymous_variant | 1.0 | ethambutol | |
embB | 4249411 | c.2898G>A | synonymous_variant | 1.0 | ethambutol | |
embB | 4249417 | c.2904A>G | synonymous_variant | 1.0 | ethambutol | |
embB | 4249424 | p.Leu971Val | missense_variant | 1.0 | ethambutol | Uncertain significance |