TB-Profiler result

Run: SRR25827507
Summary

Run ID: SRR25827507

Sample name:

Date: 2024-03-26T20:06:36.742100

Number of reads: 3853868

Percentage reads mapped: 76.22

Median coverage: 122.0

Strain: lineage4.1.1.1

Spoligotype:

Drug-resistance: MDR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.1 Euro-American None 0.94
lineage4.1.1.1 Euro-American (X-type) RD183 0.94
lineage4 Euro-American None 1.0
lineage4.1.1 Euro-American (X-type) None 0.98
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB p.Ser450Leu Assoc w R
isoniazid katG p.Ser315Thr Assoc w R High-level resistance
ethambutol embB p.His312Arg Mutation from literature
pyrazinamide pncA p.Thr142Met Assoc w R
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fbiC c.859_861delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpoB 761155 p.Ser450Leu missense_variant 0.66 rifampicin Assoc w R
fbiC 1303789 c.859_861delATCinsGG frameshift_variant&missense_variant 0.21 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.47 streptomycin Uncertain significance Mutation from literature
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid Assoc w R High-level resistance
pncA 2288817 p.Thr142Met missense_variant 1.0 pyrazinamide Assoc w R
embB 4247448 p.His312Arg missense_variant 0.27 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 756 c.756T>C synonymous_variant 0.19 isoniazid
dnaA 768 c.768C>G synonymous_variant 0.21 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.21 isoniazid
dnaA 786 c.786C>T synonymous_variant 0.21 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.24 isoniazid Not assoc w R - Interim
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.25 isoniazid Uncertain significance
dnaA 813 c.813C>T synonymous_variant 0.26 isoniazid
dnaA 819 c.819C>T synonymous_variant 0.25 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.25 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.25 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.25 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.26 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.27 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.27 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.26 isoniazid
dnaA 876 c.876C>G synonymous_variant 0.24 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.24 isoniazid
dnaA 882 c.882C>T synonymous_variant 0.23 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.23 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.26 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.25 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>G synonymous_variant 0.24 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.24 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.25 isoniazid Not assoc w R - Interim
dnaA 942 c.942C>G synonymous_variant 0.28 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.27 isoniazid
dnaA 955 c.955A>C synonymous_variant 0.28 isoniazid
dnaA 960 c.960C>A synonymous_variant 0.27 isoniazid
dnaA 963 c.963C>G synonymous_variant 0.26 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.27 isoniazid
dnaA 969 c.969G>A synonymous_variant 0.28 isoniazid
dnaA 975 c.975G>T synonymous_variant 0.29 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.3 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>G synonymous_variant 0.3 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 0.29 isoniazid
dnaA 996 c.996A>G synonymous_variant 0.28 isoniazid
dnaA 999 c.999C>G synonymous_variant 0.3 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.29 isoniazid Not assoc w R - Interim
dnaA 1014 c.1014C>G synonymous_variant 0.29 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.28 isoniazid
dnaA 1038 c.1038A>T synonymous_variant 0.29 isoniazid
dnaA 1041 c.1041G>A synonymous_variant 0.3 isoniazid
dnaA 1047 c.1047A>G synonymous_variant 0.31 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.36 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.34 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.33 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.32 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.32 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.33 isoniazid
dnaA 1125 c.1125G>C synonymous_variant 0.31 isoniazid
dnaA 1137 c.1137C>G synonymous_variant 0.31 isoniazid
dnaA 1143 c.1143G>C synonymous_variant 0.3 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.28 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 0.27 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.27 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 0.27 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 0.27 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 0.26 isoniazid
dnaA 1188 c.1188G>A synonymous_variant 0.21 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.21 isoniazid
dnaA 1197 c.1197T>C synonymous_variant 0.18 isoniazid Not assoc w R - Interim
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
ccsA 619507 c.-384A>G upstream_gene_variant 0.22 capreomycin
amikacin
kanamycin
ccsA 619528 c.-363C>G upstream_gene_variant 0.22 capreomycin
amikacin
kanamycin
ccsA 619531 c.-360T>C upstream_gene_variant 0.22 capreomycin
amikacin
kanamycin
ccsA 619535 c.-356_-354delCAAinsGCG upstream_gene_variant 0.21 capreomycin
amikacin
kanamycin
ccsA 619543 c.-348C>G upstream_gene_variant 0.23 capreomycin
amikacin
kanamycin
ccsA 619552 c.-339A>G upstream_gene_variant 0.23 capreomycin
amikacin
kanamycin
ccsA 619555 c.-336C>G upstream_gene_variant 0.22 capreomycin
amikacin
kanamycin
ccsA 619561 c.-330G>C upstream_gene_variant 0.22 capreomycin
amikacin
kanamycin
ccsA 619570 c.-321G>C upstream_gene_variant 0.21 capreomycin
amikacin
kanamycin
ccsA 619574 c.-317G>A upstream_gene_variant 0.21 capreomycin
amikacin
kanamycin
ccsA 619579 c.-312G>C upstream_gene_variant 0.2 capreomycin
amikacin
kanamycin
ccsA 619584 c.-307A>T upstream_gene_variant 0.21 capreomycin
amikacin
kanamycin
Rv0565c 657269 p.Ser68Pro missense_variant 0.95 ethionamide Uncertain significance
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.19 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.23 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.24 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.27 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.27 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.27 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.28 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.31 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 0.24 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.24 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.21 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.21 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.23 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.26 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.34 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.34 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.39 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.39 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.43 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.4 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.41 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.37 rifampicin
rpoB 760412 c.606C>G synonymous_variant 0.34 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.27 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.24 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.25 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.26 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.24 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>T synonymous_variant 0.19 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.26 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.29 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 0.28 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.43 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.46 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 0.41 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.34 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.36 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.38 rifampicin
rpoB 761219 c.1413G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 0.42 rifampicin
rpoB 761312 c.1506G>C synonymous_variant 0.41 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.4 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.32 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.28 rifampicin
rpoB 761373 p.Val523His missense_variant 0.26 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 0.25 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 761588 c.1782C>T synonymous_variant 0.36 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.36 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.28 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.2 rifampicin
rpoB 762008 c.2202C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.24 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.23 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.21 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762206 c.2400C>G synonymous_variant 0.24 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762246 c.2440C>T synonymous_variant 0.28 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.27 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.28 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.27 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762314 c.2508C>T synonymous_variant 0.27 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.28 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.27 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.25 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.25 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.24 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.24 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.24 rifampicin
rpoB 762413 c.2607G>A synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 762419 c.-951C>G upstream_gene_variant 0.24 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 0.29 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 762467 c.-903C>T upstream_gene_variant 0.3 rifampicin
rpoB 762488 c.2682G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.26 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.23 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.24 rifampicin
rpoC 762521 c.-849C>T upstream_gene_variant 0.25 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.21 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.19 rifampicin
rpoB 762810 p.Ala1002Ser missense_variant 0.2 rifampicin
rpoB 762813 p.Met1003Val missense_variant 0.21 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.3 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 763013 c.-357C>G upstream_gene_variant 0.31 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.41 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.4 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763190 c.-180C>T upstream_gene_variant 0.32 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.3 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.29 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.28 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.27 rifampicin
rpoB 763227 c.3421C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 763238 c.3432T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.21 rifampicin
rpoC 763402 c.33C>G synonymous_variant 0.26 rifampicin
rpoC 763411 c.42T>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.3 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.37 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.46 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.3 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.37 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.37 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.35 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.35 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.33 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.35 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.35 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.34 rifampicin
rpoC 763853 p.Val162Ile missense_variant 0.32 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.32 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.27 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.28 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.28 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.28 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.27 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.27 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763954 c.585C>G synonymous_variant 0.19 rifampicin
rpoC 763963 c.594C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.21 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.22 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.24 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.25 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.26 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.31 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.32 rifampicin
rpoC 764112 p.Tyr248Phe missense_variant 0.34 rifampicin
rpoC 764116 c.747C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.3 rifampicin
rpoC 764140 c.771C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ile missense_variant 0.37 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.38 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764215 c.846A>G synonymous_variant 0.4 rifampicin
rpoC 764236 c.867G>A synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764248 c.879C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.42 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.42 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.42 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.43 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764338 c.969G>A synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>C synonymous_variant 0.53 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.44 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.43 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.51 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.52 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.51 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.53 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.56 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.6 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.56 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764581 c.1212T>C synonymous_variant 0.53 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 0.51 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 0.39 rifampicin
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.39 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.35 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.4 rifampicin
rpoC 764932 c.1563C>A synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.37 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.32 rifampicin Not assoc w R
rpoC 765019 c.1650A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.27 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 0.25 rifampicin
rpoC 765076 c.1707A>G synonymous_variant 0.19 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.18 rifampicin
rpoC 765150 p.Gly594Glu missense_variant 0.95 rifampicin Not assoc w R
rpoC 765292 c.1923G>C synonymous_variant 0.2 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.21 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 0.26 rifampicin Uncertain significance
rpoC 765329 p.Ser654Gly missense_variant 0.28 rifampicin
rpoC 765346 c.1977C>G synonymous_variant 0.3 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 0.41 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.44 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.44 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.43 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.43 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.42 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.43 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.41 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.39 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.4 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.39 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.42 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.42 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.44 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.46 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.45 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.44 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.44 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.4 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.4 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.38 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.34 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.37 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.36 rifampicin
rpoC 766030 c.2661C>G synonymous_variant 0.38 rifampicin
rpoC 766036 c.2667C>T synonymous_variant 0.37 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.35 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.35 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.28 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.27 rifampicin
rpoC 766123 c.2754C>T synonymous_variant 0.2 rifampicin
rpoC 766303 c.2934C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>G synonymous_variant 0.25 rifampicin
rpoC 766327 c.2958C>A synonymous_variant 0.28 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.32 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.35 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.37 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.42 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.42 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 0.39 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.39 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.42 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.4 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 0.35 rifampicin
rpoC 766468 c.3099G>A synonymous_variant 0.34 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.33 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 0.33 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.34 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.34 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.33 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 0.32 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.34 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.34 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.33 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 0.31 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 0.3 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.31 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.31 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.35 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.33 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.32 rifampicin
rpoC 766660 c.3291G>C synonymous_variant 0.3 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.27 rifampicin
rpoC 766673 p.Gly1102Asn missense_variant 0.28 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.38 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.38 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.42 rifampicin
rpoC 766801 c.3432C>G synonymous_variant 0.37 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>T synonymous_variant 0.26 rifampicin
rpoC 766864 c.3495G>C synonymous_variant 0.27 rifampicin
rpoC 766876 c.3507C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 766882 c.3513C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 0.18 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.21 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.29 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.51 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.43 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 0.41 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 0.39 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.3 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781595 c.36T>C synonymous_variant 0.21 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.21 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.21 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.26 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.26 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.35 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.36 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.4 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.38 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.4 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.4 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.4 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.4 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.41 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.41 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.43 streptomycin
rpsL 781772 c.213C>A synonymous_variant 0.42 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.4 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.41 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.44 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.44 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.43 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.41 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.41 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.42 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.41 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.4 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.39 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.39 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.37 streptomycin Uncertain significance
rplC 800219 c.-590T>C upstream_gene_variant 1.0 linezolid
rplC 800516 c.-293G>T upstream_gene_variant 0.35 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.38 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.38 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 0.4 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.41 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.42 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.47 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.49 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.48 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.46 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.44 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.43 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.43 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.47 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.48 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.46 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.42 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.4 linezolid
rplC 800794 c.-15A>G upstream_gene_variant 0.35 linezolid
rplC 800796 c.-13A>G upstream_gene_variant 0.34 linezolid
rplC 800798 c.-10_-9delGG upstream_gene_variant 0.36 linezolid
rplC 800814 c.6A>G synonymous_variant 0.35 linezolid
rplC 800817 c.9A>T synonymous_variant 0.31 linezolid
rplC 800844 c.36T>C synonymous_variant 0.32 linezolid
rplC 800865 c.57A>G synonymous_variant 0.21 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.22 linezolid
rplC 800874 c.66A>G synonymous_variant 0.21 linezolid
rplC 800875 c.67_69delGTAinsAT frameshift_variant&missense_variant 0.21 linezolid
rplC 800880 c.72A>G synonymous_variant 0.22 linezolid
rplC 800889 c.81C>G synonymous_variant 0.22 linezolid
rplC 800892 c.84G>C synonymous_variant 0.21 linezolid
rplC 800907 c.99C>G synonymous_variant 0.22 linezolid
rplC 800916 c.108A>G synonymous_variant 0.2 linezolid
rplC 801423 c.615G>C synonymous_variant 0.2 linezolid
rplC 801426 c.618C>G synonymous_variant 0.2 linezolid
rplC 801427 p.Met207Val missense_variant 0.21 linezolid
rplC 801438 c.630T>C synonymous_variant 0.25 linezolid
rplC 801442 p.Ile212Val missense_variant 0.27 linezolid
fbiC 1303512 c.582T>C synonymous_variant 0.2 clofazimine
pretomanid
delamanid
fbiC 1303534 p.Ser202Ala missense_variant 0.22 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.2 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.2 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.23 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 0.19 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 0.18 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.18 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.19 clofazimine
pretomanid
delamanid
fbiC 1303761 c.831T>C synonymous_variant 0.19 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fbiC 1303797 c.867A>G synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1303836 c.906G>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1303845 c.915C>G synonymous_variant 0.23 clofazimine
pretomanid
delamanid
fbiC 1303846 p.Phe306Val missense_variant 0.23 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1303866 p.Glu312Asp missense_variant 0.26 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 0.28 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fbiC 1303914 c.984C>G synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fbiC 1303920 c.990C>T synonymous_variant 0.23 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.19 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.19 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.18 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 0.19 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.22 clofazimine
pretomanid
delamanid
fbiC 1304875 p.Ile649Val missense_variant 0.24 clofazimine
pretomanid
delamanid
fbiC 1304883 p.Glu651Asp missense_variant 0.26 clofazimine
pretomanid
delamanid
fbiC 1304891 p.Ile654Thr missense_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 0.28 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.28 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 0.22 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 0.18 clofazimine
pretomanid
delamanid
sigE 1364820 c.408A>G synonymous_variant 0.19 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.19 pyrazinamide
atpE 1461107 c.63C>G synonymous_variant 0.21 bedaquiline
atpE 1461113 c.69C>T synonymous_variant 0.23 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.31 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.34 bedaquiline
atpE 1461150 c.106_108delATCinsGT frameshift_variant&missense_variant 0.34 bedaquiline
atpE 1461158 c.114T>G synonymous_variant 0.34 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.33 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.32 bedaquiline
atpE 1461185 c.141G>T synonymous_variant 0.3 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.3 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.31 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.25 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.18 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.27 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.27 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.28 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.27 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.27 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.27 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.27 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.28 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.31 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472045 n.200T>A non_coding_transcript_exon_variant 0.31 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.34 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.35 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.38 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.35 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.36 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.34 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.34 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.34 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.37 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.38 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.26 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1473987 n.330G>A non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.39 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1474410 n.756_766delACCCACACGCG non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1474427 n.770A>C non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1474429 n.772G>C non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1474960 n.1303C>G non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1474963 n.1306G>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1474965 n.1308G>C non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.39 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.37 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476031 n.2374C>T non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1476108 n.2451T>C non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1476214 n.2557G>A non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.45 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.48 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
fabG1 1673368 c.-72A>G upstream_gene_variant 0.99 ethionamide
isoniazid
rpsA 1833554 p.Thr5Ala missense_variant 0.24 pyrazinamide Uncertain significance
rpsA 1833568 c.27G>C synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.37 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.39 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.43 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.44 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.44 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.44 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.43 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.41 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.41 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.42 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.47 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.46 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.48 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.46 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.44 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.44 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.46 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.45 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.45 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.44 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.44 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.45 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.44 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.44 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.42 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.39 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.24 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.23 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.22 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 0.2 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.22 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.25 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.26 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.25 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.22 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.21 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.19 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
rpsA 1834262 c.721_723delTCGinsAGC synonymous_variant 0.19 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.2 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.2 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.19 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.23 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.27 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.27 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.27 pyrazinamide
rpsA 1834684 c.1143C>T synonymous_variant 0.27 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.27 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.25 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.26 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.24 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.24 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.23 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 0.2 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.19 pyrazinamide
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
bacA 2064942 c.-214G>A upstream_gene_variant 0.2 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064948 c.-220G>C upstream_gene_variant 0.21 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 0.24 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 0.24 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 0.24 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.24 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.25 streptomycin
kanamycin
capreomycin
amikacin
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
pncA 2290015 c.-774A>C upstream_gene_variant 0.19 pyrazinamide
pncA 2290024 c.-783C>G upstream_gene_variant 0.19 pyrazinamide
kasA 2517950 c.-165C>G upstream_gene_variant 0.23 isoniazid
kasA 2518768 c.654C>T synonymous_variant 0.2 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.2 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.2 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.2 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.24 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.21 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.21 isoniazid
kasA 2518887 p.Gly258Asp missense_variant 0.2 isoniazid
kasA 2518910 p.Leu266Met missense_variant 0.2 isoniazid
kasA 2518936 c.822C>G synonymous_variant 0.19 isoniazid
kasA 2518939 c.825T>C synonymous_variant 0.19 isoniazid
kasA 2518942 c.828T>C synonymous_variant 0.2 isoniazid
kasA 2518954 c.840C>G synonymous_variant 0.21 isoniazid
kasA 2518963 c.849T>C synonymous_variant 0.2 isoniazid
kasA 2518969 c.855T>G synonymous_variant 0.22 isoniazid
kasA 2518975 c.861C>G synonymous_variant 0.23 isoniazid
kasA 2518979 c.865A>C synonymous_variant 0.21 isoniazid
ahpC 2726210 c.18T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
folC 2746534 c.1065T>C synonymous_variant 0.21 para-aminosalicylic_acid
folC 2746564 c.1035A>G synonymous_variant 0.19 para-aminosalicylic_acid
folC 2747264 p.Gly112Ala missense_variant 0.26 para-aminosalicylic_acid
folC 2747266 c.333C>T synonymous_variant 0.26 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 0.27 para-aminosalicylic_acid
folC 2747289 p.Pro104Ala missense_variant 0.26 para-aminosalicylic_acid
folC 2747290 c.309A>G synonymous_variant 0.26 para-aminosalicylic_acid
folC 2747293 c.306G>A synonymous_variant 0.26 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 0.27 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 0.29 para-aminosalicylic_acid
folC 2747317 c.282C>G synonymous_variant 0.3 para-aminosalicylic_acid
folC 2747343 p.Val86Ile missense_variant 0.33 para-aminosalicylic_acid
folC 2747355 p.Val82Ile missense_variant 0.3 para-aminosalicylic_acid
folC 2747359 c.240C>G synonymous_variant 0.28 para-aminosalicylic_acid
folC 2747362 c.237G>C synonymous_variant 0.27 para-aminosalicylic_acid
folC 2747394 p.Ile69Val missense_variant 0.19 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 0.19 para-aminosalicylic_acid
Rv2477c 2783700 p.Thr115Ser missense_variant 0.18 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.2 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.26 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.29 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.29 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.3 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.3 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.31 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.32 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.34 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 0.34 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.37 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783839 c.204C>G synonymous_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.34 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.39 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2752c 3065142 c.1050A>C synonymous_variant 0.2 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.21 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065151 c.1041G>C synonymous_variant 0.2 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065946 p.Gly82Ala missense_variant 0.22 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065955 c.235_237delTTGinsCC frameshift_variant&missense_variant 0.24 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065979 c.213T>C synonymous_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065993 p.Val67Ile missense_variant 0.33 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 0.34 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066002 p.Met64Leu missense_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066009 c.183G>C synonymous_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066018 c.174T>C synonymous_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066024 c.168T>G synonymous_variant 0.34 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066040 p.Gly51Thr missense_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066042 c.150T>C synonymous_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066045 c.147T>C synonymous_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066050 p.Leu48Met missense_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066054 c.138T>G synonymous_variant 0.29 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066066 c.126T>C synonymous_variant 0.29 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066075 c.117A>G synonymous_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066103 p.Asn30Ser missense_variant 0.22 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3066118 p.Asn25Ser missense_variant 0.2 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066501 c.-310G>C upstream_gene_variant 0.23 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066522 c.-331C>G upstream_gene_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066531 c.-340C>G upstream_gene_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.3 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066561 c.-370A>G upstream_gene_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066567 c.-376C>G upstream_gene_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066573 c.-382G>C upstream_gene_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066579 c.-388A>G upstream_gene_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066583 c.-392C>G upstream_gene_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066603 c.-412A>G upstream_gene_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066617 c.-426G>A upstream_gene_variant 0.24 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066618 c.-427A>G upstream_gene_variant 0.24 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066633 c.-442T>C upstream_gene_variant 0.22 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066638 c.-447T>G upstream_gene_variant 0.2 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066839 c.-648A>G upstream_gene_variant 0.24 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066855 c.-664T>C upstream_gene_variant 0.24 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066864 c.-673C>G upstream_gene_variant 0.24 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066867 c.-676T>C upstream_gene_variant 0.23 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066876 c.-685T>C upstream_gene_variant 0.22 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066879 c.-688T>C upstream_gene_variant 0.22 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066891 c.-700G>C upstream_gene_variant 0.21 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066900 c.-709A>G upstream_gene_variant 0.21 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066960 c.-769C>G upstream_gene_variant 0.23 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066969 c.-778G>C upstream_gene_variant 0.2 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066981 c.-790T>G upstream_gene_variant 0.19 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067232 c.714C>G synonymous_variant 0.19 para-aminosalicylic_acid
thyX 3067249 p.Thr233Ser missense_variant 0.2 para-aminosalicylic_acid
thyX 3067250 c.694_696delGTGinsAC frameshift_variant&missense_variant 0.2 para-aminosalicylic_acid
thyX 3067274 c.672C>G synonymous_variant 0.22 para-aminosalicylic_acid
thyX 3067277 c.669C>G synonymous_variant 0.21 para-aminosalicylic_acid
thyX 3067281 p.Val222Ala missense_variant 0.21 para-aminosalicylic_acid
thyX 3067284 p.Ala221Gly missense_variant 0.22 para-aminosalicylic_acid
thyX 3067286 c.660C>G synonymous_variant 0.23 para-aminosalicylic_acid
thyX 3067289 c.657C>G synonymous_variant 0.22 para-aminosalicylic_acid
thyX 3067292 c.654G>A synonymous_variant 0.22 para-aminosalicylic_acid
thyX 3067295 c.651C>T synonymous_variant 0.23 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 0.26 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.26 para-aminosalicylic_acid
thyX 3067328 c.618G>A synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.31 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.32 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 0.32 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.34 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.34 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.35 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.4 para-aminosalicylic_acid
thyX 3067445 c.501C>G synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067465 p.Ile161Val missense_variant 0.38 para-aminosalicylic_acid
thyX 3067466 c.480G>C synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 0.4 para-aminosalicylic_acid
thyX 3067490 c.456C>G synonymous_variant 0.37 para-aminosalicylic_acid
thyX 3067493 c.453A>G synonymous_variant 0.37 para-aminosalicylic_acid
thyX 3067515 p.Ser144Thr missense_variant 0.35 para-aminosalicylic_acid
thyX 3067530 p.Ala139Ser missense_variant 0.3 para-aminosalicylic_acid
thyX 3067545 p.Glu134Ala missense_variant 0.33 para-aminosalicylic_acid
thyX 3067549 p.Thr133Ala missense_variant 0.32 para-aminosalicylic_acid
thyX 3067556 p.His130Gln missense_variant 0.29 para-aminosalicylic_acid
thyX 3067559 c.387C>G synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067565 p.Asp127Glu missense_variant 0.3 para-aminosalicylic_acid
thyX 3067570 p.Ala126Pro missense_variant 0.3 para-aminosalicylic_acid
thyX 3067577 c.369G>A synonymous_variant 0.28 para-aminosalicylic_acid
thyX 3067601 p.Arg115His missense_variant 0.28 para-aminosalicylic_acid
thyX 3067611 p.Lys112Thr missense_variant 0.3 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 0.25 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 0.22 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 0.25 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 0.25 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.25 para-aminosalicylic_acid
thyX 3067685 c.261A>C synonymous_variant 0.24 para-aminosalicylic_acid
thyX 3067691 c.253_255delATCinsCG frameshift_variant&missense_variant 0.22 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.23 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.28 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067736 c.208_210delTTCinsCT frameshift_variant&missense_variant 0.27 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.26 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.26 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.27 para-aminosalicylic_acid
thyX 3067772 c.174C>G synonymous_variant 0.29 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.31 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.33 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.31 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.27 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067886 c.60A>C synonymous_variant 0.26 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.23 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 0.22 para-aminosalicylic_acid
thyX 3067935 p.Thr4Ile missense_variant 0.17 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 0.2 para-aminosalicylic_acid
thyA 3073917 c.555C>G synonymous_variant 0.2 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.21 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.2 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.2 para-aminosalicylic_acid
thyA 3073947 c.525G>A synonymous_variant 0.21 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 0.2 para-aminosalicylic_acid
thyA 3074100 c.370_372delGATinsAC frameshift_variant&synonymous_variant 0.2 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 0.2 para-aminosalicylic_acid
thyA 3074127 c.345G>C synonymous_variant 0.21 para-aminosalicylic_acid
thyA 3074130 c.342G>C synonymous_variant 0.2 para-aminosalicylic_acid
thyA 3074154 c.318T>C synonymous_variant 0.24 para-aminosalicylic_acid
thyA 3074157 c.315C>G synonymous_variant 0.23 para-aminosalicylic_acid
thyA 3074160 c.312A>G synonymous_variant 0.23 para-aminosalicylic_acid
thyA 3074163 c.307_309delGCTinsAG frameshift_variant&missense_variant 0.24 para-aminosalicylic_acid
thyA 3074172 c.300G>C synonymous_variant 0.22 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 0.23 para-aminosalicylic_acid
thyA 3074181 c.291A>G synonymous_variant 0.22 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 0.21 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.21 para-aminosalicylic_acid
thyA 3074214 c.258T>C synonymous_variant 0.2 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
lpqB 3623512 p.Gly467Ser missense_variant 0.21 bedaquiline
rifampicin
lpqB 3624143 c.768T>C synonymous_variant 0.2 bedaquiline
rifampicin
lpqB 3624166 p.Met249Leu missense_variant 0.19 bedaquiline
rifampicin
lpqB 3624167 c.744C>T synonymous_variant 0.19 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624185 c.726C>T synonymous_variant 0.19 bedaquiline
rifampicin
lpqB 3624722 c.189C>G synonymous_variant 0.2 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624728 c.183C>T synonymous_variant 0.2 bedaquiline
rifampicin
lpqB 3624749 c.162G>A synonymous_variant 0.21 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624755 c.154_156delTTAinsCG frameshift_variant&missense_variant 0.2 bedaquiline
rifampicin Uncertain significance
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
mtrB 3625222 c.1392T>C synonymous_variant 0.22 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625225 c.-315G>C upstream_gene_variant 0.23 bedaquiline
rifampicin
lpqB 3625240 c.-330T>C upstream_gene_variant 0.27 bedaquiline
rifampicin
lpqB 3625243 c.-333T>G upstream_gene_variant 0.29 bedaquiline
rifampicin
lpqB 3625255 c.-345T>C upstream_gene_variant 0.27 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 0.25 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 0.25 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 0.24 bedaquiline
rifampicin
mtrB 3625301 p.Ala438Gly missense_variant 0.21 bedaquiline
rifampicin
mtrB 3625313 p.Arg434Lys missense_variant 0.19 bedaquiline
rifampicin
lpqB 3625315 c.-405G>C upstream_gene_variant 0.19 bedaquiline
rifampicin
mtrB 3625321 c.1293A>G synonymous_variant 0.19 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625327 c.-417A>G upstream_gene_variant 0.19 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 0.19 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 0.27 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625572 p.Thr348Ser missense_variant 0.27 bedaquiline
rifampicin
lpqB 3625579 c.-669A>G upstream_gene_variant 0.31 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 0.38 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 0.38 bedaquiline
rifampicin
lpqB 3625612 c.-702G>C upstream_gene_variant 0.39 bedaquiline
rifampicin
mtrB 3625616 p.Arg333Ala missense_variant 0.38 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 0.4 bedaquiline
rifampicin
mtrB 3625636 c.978C>G synonymous_variant 0.42 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625656 c.958T>C synonymous_variant 0.43 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.41 bedaquiline
rifampicin
lpqB 3625669 c.-759G>C upstream_gene_variant 0.41 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 0.41 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 0.41 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 0.41 bedaquiline
rifampicin
mtrB 3625705 c.909C>G synonymous_variant 0.39 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625711 c.903C>T synonymous_variant 0.39 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625714 c.-804C>T upstream_gene_variant 0.37 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 0.39 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.37 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625735 c.-825C>T upstream_gene_variant 0.37 bedaquiline
rifampicin
lpqB 3625749 c.-839C>T upstream_gene_variant 0.34 bedaquiline
rifampicin
mtrB 3625750 c.864G>A synonymous_variant 0.34 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.36 bedaquiline
rifampicin Uncertain significance
mtrB 3625765 c.849C>G synonymous_variant 0.38 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625774 c.840G>A synonymous_variant 0.4 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625797 p.Val273Met missense_variant 0.39 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625806 c.808A>C synonymous_variant 0.38 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625807 c.807C>G synonymous_variant 0.38 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625837 c.777C>G synonymous_variant 0.38 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625849 c.-939T>C upstream_gene_variant 0.38 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.4 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625864 c.748_750delCGTinsAG frameshift_variant&missense_variant 0.37 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625876 c.738G>C synonymous_variant 0.35 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625903 c.-993G>C upstream_gene_variant 0.33 bedaquiline
rifampicin
lpqB 3625909 c.-999T>C upstream_gene_variant 0.33 bedaquiline
rifampicin
mtrB 3625920 c.694C>T synonymous_variant 0.26 bedaquiline
rifampicin
mtrB 3625927 c.687T>C synonymous_variant 0.21 bedaquiline
rifampicin
mtrB 3625930 c.684C>G synonymous_variant 0.21 bedaquiline
rifampicin
mtrB 3625942 c.672C>G synonymous_variant 0.19 bedaquiline
rifampicin
mtrB 3625967 p.Ala216Val missense_variant 0.18 bedaquiline
rifampicin Uncertain significance
mtrB 3626957 c.-344G>C upstream_gene_variant 0.28 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 0.38 bedaquiline
rifampicin
mtrB 3626987 c.-374C>G upstream_gene_variant 0.41 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.47 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 0.49 bedaquiline
rifampicin
mtrB 3627065 c.-452G>C upstream_gene_variant 0.37 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.37 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627071 c.279G>T synonymous_variant 0.34 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627074 c.-461G>C upstream_gene_variant 0.34 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 0.34 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 0.34 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 0.36 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 0.35 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 0.31 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>C upstream_gene_variant 0.31 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 0.26 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 0.24 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.24 bedaquiline
rifampicin
mtrA 3627188 c.162A>G synonymous_variant 0.27 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627209 c.-596G>A upstream_gene_variant 0.32 bedaquiline
rifampicin
mtrA 3627221 c.129C>T synonymous_variant 0.35 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627227 c.123T>C synonymous_variant 0.35 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627233 c.-620T>C upstream_gene_variant 0.34 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 0.34 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 0.34 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627254 c.-641C>T upstream_gene_variant 0.32 bedaquiline
rifampicin
mtrB 3627263 c.-650C>T upstream_gene_variant 0.33 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 0.33 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 0.31 bedaquiline
rifampicin
mtrB 3627275 c.-662G>T upstream_gene_variant 0.31 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 0.29 bedaquiline
rifampicin
mtrA 3627299 c.49_51delTTGinsCA frameshift_variant&missense_variant 0.29 bedaquiline
rifampicin
mtrB 3627314 c.-701C>T upstream_gene_variant 0.28 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.29 bedaquiline
rifampicin
mtrA 3627343 p.Thr3Ser missense_variant 0.23 bedaquiline
rifampicin
fbiA 3641447 p.Thr302Met missense_variant 0.99 clofazimine Not assoc w R
pretomanid
delamanid Uncertain significance
fbiB 3642656 c.1122G>C synonymous_variant 0.23 clofazimine
pretomanid
delamanid
fbiB 3642659 c.1125C>G synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fbiB 3642668 c.1134A>G synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fbiB 3642677 c.1143A>G synonymous_variant 0.23 clofazimine
pretomanid
delamanid
fbiB 3642680 c.1146A>G synonymous_variant 0.23 clofazimine
pretomanid
delamanid
fbiB 3642684 c.1150T>C synonymous_variant 0.22 clofazimine
pretomanid
delamanid
rpoA 3877494 p.Glu338Asp missense_variant 0.19 rifampicin Uncertain significance
rpoA 3877503 c.1005G>C synonymous_variant 0.24 rifampicin
rpoA 3877507 p.Gly334Ala missense_variant 0.26 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 0.27 rifampicin
rpoA 3877553 p.Glu319Gln missense_variant 0.35 rifampicin
rpoA 3877553 p.Glu319Lys missense_variant 0.64 rifampicin Not assoc w R
rpoA 3877571 p.Pro313Ala missense_variant 0.37 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.45 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.42 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 0.43 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.46 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoA 3877791 c.717C>G synonymous_variant 0.4 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.41 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.42 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 0.42 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 0.42 rifampicin
rpoA 3877890 c.618C>T synonymous_variant 0.43 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.44 rifampicin
rpoA 3877900 p.Ser203Asn missense_variant 0.43 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 0.42 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.41 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoA 3877986 c.522G>C synonymous_variant 0.41 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.37 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.34 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.34 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3878043 c.465G>A synonymous_variant 0.32 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.33 rifampicin
rpoA 3878058 c.450G>T synonymous_variant 0.33 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.32 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 0.31 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.32 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.31 rifampicin
rpoA 3878082 c.426T>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoA 3878094 c.414C>G synonymous_variant 0.33 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.32 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.31 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.33 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 0.32 rifampicin
rpoA 3878141 p.Met123Leu missense_variant 0.32 rifampicin Uncertain significance
rpoA 3878143 p.Gly122Asp missense_variant 0.3 rifampicin Uncertain significance
rpoA 3878157 c.351C>G synonymous_variant 0.3 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 0.33 rifampicin
rpoA 3878181 c.327C>T synonymous_variant 0.34 rifampicin
rpoA 3878187 c.321C>G synonymous_variant 0.34 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 0.33 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoA 3878226 c.282C>G synonymous_variant 0.34 rifampicin
rpoA 3878232 c.276G>C synonymous_variant 0.36 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.35 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3878284 p.Glu75Ala missense_variant 0.37 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.4 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoA 3878340 c.168C>T synonymous_variant 0.37 rifampicin
rpoA 3878346 c.162T>C synonymous_variant 0.41 rifampicin
rpoA 3878364 c.144A>T synonymous_variant 0.41 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.4 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 0.4 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.38 rifampicin
rpoA 3878388 c.120C>G synonymous_variant 0.37 rifampicin
rpoA 3878391 c.117T>C synonymous_variant 0.38 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.33 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.31 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.3 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.3 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 0.25 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.25 rifampicin
rpoA 3878478 c.30C>G synonymous_variant 0.24 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 0.24 rifampicin
rpoA 3878490 c.18C>A synonymous_variant 0.23 rifampicin
rpoA 3878496 c.12A>T synonymous_variant 0.17 rifampicin
rpoA 3878683 c.-176G>C upstream_gene_variant 0.43 rifampicin
rpoA 3878713 c.-206G>A upstream_gene_variant 0.38 rifampicin Uncertain significance
rpoA 3878716 c.-209C>G upstream_gene_variant 0.38 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 0.42 rifampicin
rpoA 3878736 c.-229A>G upstream_gene_variant 0.39 rifampicin
rpoA 3878737 c.-230G>C upstream_gene_variant 0.39 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.38 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 0.37 rifampicin Uncertain significance
rpoA 3878749 c.-242G>T upstream_gene_variant 0.38 rifampicin
rpoA 3878761 c.-254G>C upstream_gene_variant 0.4 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.4 rifampicin
rpoA 3878785 c.-278T>G upstream_gene_variant 0.43 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.43 rifampicin Uncertain significance
rpoA 3878806 c.-299C>G upstream_gene_variant 0.42 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.44 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 0.42 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 0.39 rifampicin
rpoA 3878836 c.-331_-329delAAGinsTCC upstream_gene_variant 0.38 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.4 rifampicin
rpoA 3878860 c.-353C>T upstream_gene_variant 0.38 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.36 rifampicin Uncertain significance
rpoA 3878909 c.-402A>G upstream_gene_variant 0.38 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.37 rifampicin Uncertain significance
rpoA 3878917 c.-410G>A upstream_gene_variant 0.36 rifampicin Uncertain significance
rpoA 3878938 c.-431T>A upstream_gene_variant 0.37 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.36 rifampicin Uncertain significance
rpoA 3878962 c.-455G>A upstream_gene_variant 0.33 rifampicin Uncertain significance
rpoA 3878968 c.-461T>C upstream_gene_variant 0.33 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.34 rifampicin Uncertain significance
rpoA 3878986 c.-479G>C upstream_gene_variant 0.35 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.35 rifampicin Uncertain significance
rpoA 3879005 c.-499_-498delAAinsCG upstream_gene_variant 0.34 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 0.35 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.37 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.36 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.36 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.4 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.4 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.39 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.38 rifampicin
rpoA 3879178 c.-671T>C upstream_gene_variant 0.32 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 0.27 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 0.24 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 0.23 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 0.23 rifampicin
rpoA 3879232 c.-725A>G upstream_gene_variant 0.22 rifampicin
clpC1 4038212 c.2493T>C synonymous_variant 0.22 pyrazinamide
clpC1 4038239 c.2466T>C synonymous_variant 0.3 pyrazinamide
clpC1 4038255 p.Val817Lys missense_variant 0.3 pyrazinamide
clpC1 4038271 p.Pro812Ala missense_variant 0.31 pyrazinamide
clpC1 4038272 c.2431_2433delGGTinsAC frameshift_variant&missense_variant 0.32 pyrazinamide
clpC1 4038275 c.2430A>G synonymous_variant 0.32 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.33 pyrazinamide
clpC1 4038293 c.2412G>C synonymous_variant 0.35 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.36 pyrazinamide
clpC1 4038308 c.2397G>T synonymous_variant 0.36 pyrazinamide
clpC1 4038314 c.2391T>C synonymous_variant 0.36 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.36 pyrazinamide
clpC1 4038320 c.2385G>T synonymous_variant 0.36 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.34 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.34 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.32 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.32 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 0.32 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.31 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4038407 c.2298G>C synonymous_variant 0.31 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 0.34 pyrazinamide
clpC1 4038433 c.2272C>T synonymous_variant 0.32 pyrazinamide
clpC1 4038434 c.2271G>A synonymous_variant 0.32 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.31 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.31 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.33 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 0.34 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 0.31 pyrazinamide
clpC1 4038489 p.Ala739Gly missense_variant 0.31 pyrazinamide
clpC1 4038494 c.2211G>C synonymous_variant 0.32 pyrazinamide
clpC1 4038497 p.Ser736Gln missense_variant 0.32 pyrazinamide
clpC1 4038509 c.2196C>T synonymous_variant 0.38 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.38 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.34 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.25 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.27 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.24 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.2 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.19 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.19 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.21 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.25 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.24 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.23 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.23 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.23 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.24 pyrazinamide
clpC1 4038749 c.1956C>A synonymous_variant 0.31 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.32 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.31 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.32 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.34 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.41 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.42 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.46 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.45 pyrazinamide Not assoc w R - Interim
clpC1 4038893 c.1812C>T synonymous_variant 0.46 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.45 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.46 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTG frameshift_variant&synonymous_variant 0.47 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.46 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.46 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.45 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.45 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.44 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.44 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.43 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.39 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.4 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.38 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.37 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.36 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.36 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.36 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.37 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.4 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.38 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.39 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.38 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.38 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.38 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 0.38 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.39 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4039229 c.1476C>G synonymous_variant 0.34 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.35 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 0.37 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.37 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.35 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 0.34 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 0.33 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 0.32 pyrazinamide
clpC1 4039349 c.1356C>T synonymous_variant 0.38 pyrazinamide
clpC1 4039352 c.1353C>G synonymous_variant 0.39 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 0.4 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.38 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.31 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.34 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.3 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.26 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.24 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.25 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.25 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.26 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.29 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.29 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.24 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039589 c.1116G>C synonymous_variant 0.21 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.26 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.23 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.22 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.19 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.2 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.18 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.21 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.3 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.3 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.32 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.34 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.33 pyrazinamide
clpC1 4039982 c.723G>A synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
clpC1 4039988 c.717C>G synonymous_variant 0.35 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.36 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.33 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.33 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.31 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.32 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.28 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.29 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.31 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.32 pyrazinamide Not assoc w R - Interim
clpC1 4040162 c.543G>C synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.3 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.33 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.33 pyrazinamide
clpC1 4040207 c.498T>G synonymous_variant 0.3 pyrazinamide
clpC1 4040210 c.495G>C synonymous_variant 0.31 pyrazinamide
clpC1 4040213 c.490_492delTCTinsAGC synonymous_variant 0.32 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 0.37 pyrazinamide
clpC1 4040228 c.477G>T synonymous_variant 0.36 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 0.42 pyrazinamide
clpC1 4040246 c.459C>G synonymous_variant 0.41 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.43 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.36 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
clpC1 4040276 c.427_429delTCCinsAGT synonymous_variant 0.3 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.37 pyrazinamide
clpC1 4040318 c.387C>G synonymous_variant 0.37 pyrazinamide
clpC1 4040330 c.375C>G synonymous_variant 0.32 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 0.3 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.32 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.31 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.31 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.3 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.29 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.29 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.3 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.3 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 0.27 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.22 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.22 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.22 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.22 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.21 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.23 pyrazinamide
panD 4044700 c.-419C>A upstream_gene_variant 0.18 pyrazinamide
panD 4044712 c.-431C>A upstream_gene_variant 0.18 pyrazinamide
panD 4044725 c.-444C>T upstream_gene_variant 0.2 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 0.19 pyrazinamide
panD 4044746 c.-467_-465delGTGinsAC upstream_gene_variant 0.19 pyrazinamide
panD 4044909 c.-628C>T upstream_gene_variant 0.18 pyrazinamide
panD 4044917 c.-636G>C upstream_gene_variant 0.2 pyrazinamide
panD 4044926 c.-645C>A upstream_gene_variant 0.2 pyrazinamide
panD 4044929 c.-648G>C upstream_gene_variant 0.2 pyrazinamide
panD 4044935 c.-655_-654delAAinsTG upstream_gene_variant 0.22 pyrazinamide
panD 4044941 c.-660G>C upstream_gene_variant 0.23 pyrazinamide
panD 4044954 c.-674_-673delCCinsAT upstream_gene_variant 0.22 pyrazinamide
panD 4044980 c.-699A>G upstream_gene_variant 0.25 pyrazinamide
panD 4044983 c.-702G>T upstream_gene_variant 0.25 pyrazinamide
panD 4044989 c.-708T>C upstream_gene_variant 0.27 pyrazinamide
panD 4045000 c.-719A>C upstream_gene_variant 0.22 pyrazinamide
panD 4045001 c.-720G>C upstream_gene_variant 0.22 pyrazinamide
embC 4240831 c.969T>G synonymous_variant 0.21 ethambutol
embC 4240897 c.1035C>G synonymous_variant 0.99 ethambutol Not assoc w R
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embC 4242803 p.Val981Leu missense_variant 0.98 ethambutol Not assoc w R
embA 4245785 c.2553G>C synonymous_variant 0.23 ethambutol Not assoc w R - Interim
embA 4245807 c.2575_2577delTTAinsCG frameshift_variant&missense_variant 0.28 ethambutol Uncertain significance
embB 4245812 c.-702G>C upstream_gene_variant 0.3 ethambutol
embA 4245813 c.2581_2583delCCCinsGG frameshift_variant&missense_variant 0.29 ethambutol Uncertain significance
embA 4245820 p.Ser863Thr missense_variant 0.29 ethambutol
embB 4245824 c.-690G>C upstream_gene_variant 0.28 ethambutol
embB 4245833 c.-681G>C upstream_gene_variant 0.3 ethambutol
embB 4245842 c.-672G>C upstream_gene_variant 0.29 ethambutol
embB 4245845 c.-669T>C upstream_gene_variant 0.28 ethambutol
embB 4245851 c.-663G>C upstream_gene_variant 0.3 ethambutol
embB 4245860 c.-654C>G upstream_gene_variant 0.29 ethambutol
embB 4246097 c.-417C>G upstream_gene_variant 0.2 ethambutol
embB 4246115 c.-399T>G upstream_gene_variant 0.2 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 0.19 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 0.21 ethambutol
embB 4246316 c.-198T>G upstream_gene_variant 0.2 ethambutol
embA 4246329 p.Thr1033Ala missense_variant 0.2 ethambutol
embB 4247407 c.894G>C synonymous_variant 0.21 ethambutol
embB 4247425 c.912G>C synonymous_variant 0.26 ethambutol
embB 4247434 c.921C>A synonymous_variant 0.26 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.27 ethambutol Not assoc w R - Interim
embB 4247440 c.927C>G synonymous_variant 0.27 ethambutol
embB 4247446 c.933C>T synonymous_variant 0.27 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.29 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.3 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.31 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.3 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.29 ethambutol
embB 4247539 c.1026T>C synonymous_variant 0.26 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.22 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.18 ethambutol
embB 4249408 c.2895G>A synonymous_variant 1.0 ethambutol Not assoc w R
embB 4249580 p.Leu1023Met missense_variant 0.18 ethambutol
aftB 4268099 c.738G>C synonymous_variant 0.2 ethambutol
aftB 4268102 c.735C>G synonymous_variant 0.22 ethambutol Not assoc w R - Interim
aftB 4268117 c.720G>C synonymous_variant 0.22 ethambutol
aftB 4268123 c.712_714delAGTinsGC frameshift_variant&synonymous_variant 0.22 ethambutol Uncertain significance
aftB 4268129 c.708T>G synonymous_variant 0.22 ethambutol
aftB 4268138 c.699A>C synonymous_variant 0.22 ethambutol Not assoc w R - Interim
aftB 4268144 c.693T>C synonymous_variant 0.21 ethambutol
aftB 4268164 p.Gln225Glu missense_variant 0.2 ethambutol
aftB 4268169 p.Ala223Gly missense_variant 0.21 ethambutol
aftB 4268171 c.666G>C synonymous_variant 0.2 ethambutol
aftB 4268183 c.654A>T synonymous_variant 0.19 ethambutol
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin