TB-Profiler result

Run: 728d0b23-381e-4124-8fcc-5f6adfb585f2
Summary

Run ID: 728d0b23-381e-4124-8fcc-5f6adfb585f2

Sample name:

Date: 29-08-2023 05:21:24

Number of reads: 121057

Percentage reads mapped: 4.35

Median coverage: 0

Strain: lineage4.9;lineage2.1

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage3 East-African-Indian RD750 0.14
lineage2.1 East-Asian (non-Beijing) None 0.8
lineage4.9 Euro-American (H37Rv-like) None 1.0
lineage4.1.4 Euro-American None 0.92
lineage1.1.1 Indo-Oceanic RD239 0.08
lineage6.3.1 West-Africa 2 RD702 0.7
lineage3.1.2.2 East-African-Indian RD750 0.76
lineage4.4.1.2 Euro-American None 0.59
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
moxifloxacin
levofloxacin
bedaquiline
delamanid
pretomanid
linezolid
streptomycin
amikacin
kanamycin
capreomycin
clofazimine
ethionamide
para-aminosalicylic_acid
cycloserine
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrA 6640 c.-662A>C upstream_gene_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7703 c.402G>C synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7710 c.409T>C synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7715 c.414G>C synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 7763 c.462T>C synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8924 c.1623C>T synonymous_variant 0.8 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8946 c.1645T>C synonymous_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8967 p.Ala556Asn missense_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.87 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.86 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9017 c.1716C>G synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9023 c.1722A>T synonymous_variant 0.85 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9029 c.1728T>G synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.83 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9038 c.1737C>G synonymous_variant 0.82 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9304 p.Gly668Glu missense_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9308 p.Asp669Glu missense_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9323 c.2022C>T synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9326 c.2025G>C synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9335 c.2034G>C synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9368 c.2067G>A synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
gyrA 9377 c.2076A>C synonymous_variant 1.0 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
fgd1 491563 c.781_782delAGinsTC synonymous_variant 0.7 delamanid
fgd1 491574 c.792C>T synonymous_variant 0.7 delamanid
fgd1 491580 c.798C>A synonymous_variant 0.7 delamanid
fgd1 491590 p.Lys270Ala missense_variant 0.7 delamanid
rpoB 760157 c.351A>G synonymous_variant 1.0 rifampicin
rpoB 760160 p.Asp118Glu missense_variant 1.0 rifampicin
rpoB 760167 p.Met121Gln missense_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin
rpoB 760216 p.Asn137Thr missense_variant 1.0 rifampicin
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin
rpoB 760274 c.468G>A synonymous_variant 1.0 rifampicin
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin
rpoB 760356 p.Thr184Ser missense_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin
rpoB 760368 p.Ser188Ala missense_variant 1.0 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin
rpoB 760382 c.576G>C synonymous_variant 1.0 rifampicin
rpoB 760997 c.1191G>C synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin
rpoB 761051 c.1245G>T synonymous_variant 1.0 rifampicin
rpoB 761054 c.1248G>C synonymous_variant 1.0 rifampicin
rpoB 761057 c.1251G>C synonymous_variant 1.0 rifampicin
rpoB 761060 c.1254C>G synonymous_variant 1.0 rifampicin
rpoB 761063 c.1257C>G synonymous_variant 1.0 rifampicin
rpoB 761084 c.1278C>A synonymous_variant 1.0 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.91 rifampicin
rpoB 761133 c.1327T>C synonymous_variant 0.91 rifampicin
rpoB 761147 c.1341C>T synonymous_variant 0.92 rifampicin
rpoB 761150 c.1344A>T synonymous_variant 0.92 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.86 rifampicin
rpoB 761171 c.1365C>T synonymous_variant 0.87 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 0.88 rifampicin
rpoB 761189 c.1383T>C synonymous_variant 0.88 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 0.88 rifampicin
rpoB 761198 c.1392G>C synonymous_variant 0.87 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.85 rifampicin
rpoB 761217 p.Pro471Ser missense_variant 0.85 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.8 rifampicin
rpoB 761243 c.1437G>C synonymous_variant 0.83 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.86 rifampicin
rpoB 761258 c.1452G>A synonymous_variant 0.86 rifampicin
rpoB 761261 c.1455G>C synonymous_variant 0.86 rifampicin
rpoB 761264 c.1458C>G synonymous_variant 0.92 rifampicin
rpoB 761306 c.1500C>G synonymous_variant 0.9 rifampicin
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin
rpoB 762104 c.2298C>T synonymous_variant 1.0 rifampicin
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762134 c.2328C>T synonymous_variant 1.0 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin
rpoB 762158 c.2352G>C synonymous_variant 1.0 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin
rpoB 762239 c.2433G>A synonymous_variant 1.0 rifampicin
rpoB 762245 c.2439G>C synonymous_variant 1.0 rifampicin
rpoB 762278 c.2472C>T synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin
rpoB 762336 p.Ile844Val missense_variant 1.0 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762350 c.2544C>G synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762368 p.Glu854Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoC 762404 c.-966T>C upstream_gene_variant 1.0 rifampicin
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoC 762416 c.-954A>G upstream_gene_variant 1.0 rifampicin
rpoC 762428 c.-942C>T upstream_gene_variant 1.0 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 1.0 rifampicin
rpoC 762452 c.-918G>C upstream_gene_variant 1.0 rifampicin
rpoC 762470 c.-900G>C upstream_gene_variant 0.82 rifampicin
rpoC 762485 c.-885G>C upstream_gene_variant 0.82 rifampicin
rpoB 762489 p.Val895Gln missense_variant 0.82 rifampicin
rpoB 762507 p.Leu901Met missense_variant 0.75 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.73 rifampicin Uncertain significance
rpoB 762879 p.Met1025Leu missense_variant 1.0 rifampicin
rpoC 762894 c.-476C>T upstream_gene_variant 0.93 rifampicin
rpoC 762899 c.-471G>C upstream_gene_variant 1.0 rifampicin
rpoC 762917 c.-453C>G upstream_gene_variant 0.94 rifampicin
rpoC 762920 c.-450C>T upstream_gene_variant 1.0 rifampicin
rpoC 762923 c.-447C>G upstream_gene_variant 1.0 rifampicin
rpoC 762929 c.-441G>C upstream_gene_variant 1.0 rifampicin
rpoC 762959 c.-411G>C upstream_gene_variant 0.88 rifampicin
rpoC 762962 c.-408C>T upstream_gene_variant 0.88 rifampicin
rpoC 762965 c.-405T>C upstream_gene_variant 0.12 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 0.13 rifampicin
rpoC 762995 c.-375G>T upstream_gene_variant 0.91 rifampicin
rpoC 763031 c.-339T>G upstream_gene_variant 1.0 rifampicin
rpoC 763034 c.-336C>G upstream_gene_variant 1.0 rifampicin
rpoC 763040 c.-330C>G upstream_gene_variant 1.0 rifampicin
rpoC 763053 c.-317T>C upstream_gene_variant 1.0 rifampicin
rpoC 763070 c.-300T>C upstream_gene_variant 1.0 rifampicin
rpoC 763082 c.-288C>T upstream_gene_variant 1.0 rifampicin
rpoC 763088 c.-282C>G upstream_gene_variant 1.0 rifampicin
rpoC 763094 c.-276G>C upstream_gene_variant 1.0 rifampicin
rpoC 763115 c.-255T>C upstream_gene_variant 1.0 rifampicin
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin
rpoC 763495 c.126G>A synonymous_variant 1.0 rifampicin
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 1.0 rifampicin
rpoC 764410 c.1041G>C synonymous_variant 1.0 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.29 rifampicin
rpoC 764429 c.1060C>T synonymous_variant 0.71 rifampicin
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.73 rifampicin
rpoC 764450 p.Gly361Arg missense_variant 0.27 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.75 rifampicin
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin
rpoC 764471 p.Asn368Arg missense_variant 0.28 rifampicin
rpoC 764479 c.1110G>A synonymous_variant 0.28 rifampicin
rpoC 764485 c.1116G>C synonymous_variant 1.0 rifampicin
rpoC 764498 p.Ser377Ala missense_variant 0.18 rifampicin
rpoC 764503 c.1134G>T synonymous_variant 0.18 rifampicin
rpoC 764509 c.1140G>C synonymous_variant 0.19 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 0.82 rifampicin
rpoC 764530 c.1161C>T synonymous_variant 0.88 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin
rpoC 764542 c.1173C>G synonymous_variant 1.0 rifampicin
rpoC 764548 c.1179G>T synonymous_variant 1.0 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 0.22 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.32 rifampicin
rpoC 764582 p.Leu405Met missense_variant 0.32 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.58 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin
rpoC 764620 c.1251G>T synonymous_variant 0.53 rifampicin
rpoC 764623 c.1254C>G synonymous_variant 0.97 rifampicin
rpoC 764632 c.1263T>C synonymous_variant 0.95 rifampicin
rpoC 764641 c.1272C>T synonymous_variant 0.57 rifampicin
rpoC 764647 c.1278C>T synonymous_variant 0.58 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.97 rifampicin
rpoC 764663 p.Val432Thr missense_variant 0.58 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 0.59 rifampicin
rpoC 764672 p.Gln435Glu missense_variant 0.59 rifampicin
rpoC 764692 c.1323C>T synonymous_variant 0.38 rifampicin
rpoC 764695 c.1326T>C synonymous_variant 0.57 rifampicin
rpoC 764701 c.1332C>G synonymous_variant 0.49 rifampicin
rpoC 764705 p.Leu446* stop_gained 0.94 rifampicin
rpoC 764713 c.1344G>C synonymous_variant 0.5 rifampicin
rpoC 764716 c.1347G>C synonymous_variant 0.96 rifampicin
rpoC 764719 c.1350G>A synonymous_variant 0.41 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 0.88 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.88 rifampicin
rpoC 764758 c.1389C>G synonymous_variant 0.88 rifampicin
rpoC 764764 c.1395T>C synonymous_variant 0.88 rifampicin
rpoC 764797 c.1428G>C synonymous_variant 0.93 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.93 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 0.94 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.94 rifampicin
rpoC 764827 c.1458G>C synonymous_variant 0.94 rifampicin
rpoC 764843 p.Ala492Ser missense_variant 0.93 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.94 rifampicin
rpoC 764869 c.1500C>T synonymous_variant 0.89 rifampicin
rpoC 764875 c.1506C>T synonymous_variant 0.93 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.87 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 1.0 rifampicin
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764912 p.Met515Gln missense_variant 1.0 rifampicin
rpoC 764935 c.1566T>C synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765422 p.Asn685Asp missense_variant 1.0 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 1.0 rifampicin
rpoC 765454 c.2085C>G synonymous_variant 1.0 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 1.0 rifampicin
rpoC 765469 c.2100G>C synonymous_variant 1.0 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin
rpoC 767080 c.3711G>C synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin
rpoC 767105 p.Asn1246Gln missense_variant 1.0 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin
rpoC 767155 c.3786C>G synonymous_variant 1.0 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 1.0 rifampicin
rpsL 781685 c.126G>C synonymous_variant 1.0 streptomycin
rpsL 781703 c.144G>T synonymous_variant 1.0 streptomycin
rpsL 781706 c.147T>G synonymous_variant 1.0 streptomycin
rpsL 781709 c.150G>C synonymous_variant 1.0 streptomycin
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781742 c.183C>T synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.91 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.92 streptomycin
rpsL 781766 c.207C>T synonymous_variant 1.0 streptomycin
rpsL 781769 c.210G>A synonymous_variant 1.0 streptomycin
rpsL 781802 c.243G>C synonymous_variant 1.0 streptomycin
rpsL 781808 c.249C>T synonymous_variant 1.0 streptomycin
rpsL 781814 c.255C>T synonymous_variant 1.0 streptomycin
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781829 c.270G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781859 c.300T>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781907 c.348T>C synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 1.0 streptomycin
fbiC 1304613 c.1683T>C synonymous_variant 1.0 delamanid
fbiC 1304617 c.1687C>A synonymous_variant 1.0 delamanid
fbiC 1304628 c.1698G>C synonymous_variant 1.0 delamanid
fbiC 1304634 c.1704C>G synonymous_variant 1.0 delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 delamanid
fbiC 1304675 p.Gly582Asp missense_variant 1.0 delamanid
fbiC 1304691 c.1761G>C synonymous_variant 1.0 delamanid
fbiC 1304694 c.1764A>C synonymous_variant 1.0 delamanid
fbiC 1304703 c.1773C>G synonymous_variant 1.0 delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 delamanid
rrs 1471892 n.47G>A non_coding_transcript_exon_variant 0.18 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1471896 n.51T>C non_coding_transcript_exon_variant 0.18 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471931 n.87delA non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472028 n.183A>G non_coding_transcript_exon_variant 0.62 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472030 n.185G>A non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472031 n.186G>T non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 1.0 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0 linezolid
kanamycin Uncertain significance
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.12 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.22 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.29 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.34 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.24 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.3 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 0.22 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin Uncertain significance
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.23 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.3 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.27 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin Uncertain significance
rrs 1472349 n.504A>C non_coding_transcript_exon_variant 0.2 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.91 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.98 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.98 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472672 n.830delT non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.11 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.1 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.15 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.86 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472770 n.925C>T non_coding_transcript_exon_variant 0.12 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.1 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472847 n.1002G>T non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472860 n.1015C>A non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472951 n.1106T>C non_coding_transcript_exon_variant 0.94 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472953 n.1108G>A non_coding_transcript_exon_variant 0.94 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 1.0 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 1.0 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 1.0 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473100 n.1255G>T non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.67 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473118 n.1275dupC non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473123 n.1278A>G non_coding_transcript_exon_variant 1.0 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 1.0 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrl 1473697 n.40_41insA non_coding_transcript_exon_variant 1.0 linezolid
rrl 1473700 n.44delA non_coding_transcript_exon_variant 1.0 linezolid
rrl 1473717 n.60G>A non_coding_transcript_exon_variant 1.0 linezolid Uncertain significance
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 1.0 linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1473797 n.140G>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1473922 n.265A>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.8 linezolid
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.92 linezolid
rrl 1474156 n.499G>A non_coding_transcript_exon_variant 0.92 linezolid
rrl 1474163 n.506C>T non_coding_transcript_exon_variant 0.92 linezolid
rrl 1474178 n.522dupC non_coding_transcript_exon_variant 0.86 linezolid
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.86 linezolid
rrl 1474183 n.527delC non_coding_transcript_exon_variant 0.86 linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.92 linezolid
rrl 1474293 n.636T>A non_coding_transcript_exon_variant 0.86 linezolid
rrl 1474294 n.638_649delCTCTCCGGAGGA non_coding_transcript_exon_variant 0.86 linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.86 linezolid
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.86 linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.92 linezolid
rrl 1474376 n.719T>G non_coding_transcript_exon_variant 0.89 linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.89 linezolid
rrl 1474416 n.760_774delACACGCGCATACGCG non_coding_transcript_exon_variant 0.91 linezolid
rrl 1474434 n.777_778insAAGG non_coding_transcript_exon_variant 0.91 linezolid
rrl 1474437 n.781_782delAA non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474715 n.1060_1061insGACAAA non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475061 n.1404C>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475108 n.1451C>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475126 n.1469G>C non_coding_transcript_exon_variant 0.1 linezolid
rrl 1475343 n.1686A>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 linezolid Uncertain significance
rrl 1475358 n.1701T>C non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475375 n.1718G>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475376 n.1719A>C non_coding_transcript_exon_variant 1.0 linezolid Uncertain significance
rrl 1475379 n.1722G>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475398 n.1741C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475401 n.1745delC non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475406 n.1749T>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475407 n.1750C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475430 n.1773T>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475467 n.1810G>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 1.0 linezolid Uncertain significance
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475487 n.1830C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475602 n.1945G>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475603 n.1946G>C non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475629 n.1972_1973insT non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.13 linezolid
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.17 linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 linezolid Uncertain significance
rrl 1475989 n.2332T>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1476088 n.2431A>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 linezolid
rrl 1476114 n.2457T>C non_coding_transcript_exon_variant 1.0 linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 linezolid
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.95 linezolid
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 1.0 linezolid
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.98 linezolid
rrl 1476336 n.2679C>G non_coding_transcript_exon_variant 0.26 linezolid
rrl 1476356 n.2699C>G non_coding_transcript_exon_variant 0.41 linezolid
rrl 1476357 n.2700T>A non_coding_transcript_exon_variant 0.41 linezolid
rrl 1476359 n.2702C>T non_coding_transcript_exon_variant 0.43 linezolid
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 0.45 linezolid
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.52 linezolid
rrl 1476381 n.2724G>A non_coding_transcript_exon_variant 0.51 linezolid
rrl 1476384 n.2727G>C non_coding_transcript_exon_variant 0.55 linezolid
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.56 linezolid
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.53 linezolid
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.52 linezolid
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.52 linezolid
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.52 linezolid
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.55 linezolid Uncertain significance
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.49 linezolid
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.45 linezolid
rrl 1476491 n.2834T>C non_coding_transcript_exon_variant 0.31 linezolid
rrl 1476501 n.2844C>T non_coding_transcript_exon_variant 0.29 linezolid
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.32 linezolid
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.23 linezolid
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.22 linezolid
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.22 linezolid
rrl 1476524 n.2868delA non_coding_transcript_exon_variant 0.17 linezolid
rrl 1476528 n.2871A>T non_coding_transcript_exon_variant 0.17 linezolid
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.1 linezolid
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.1 linezolid
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.1 linezolid
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 0.93 linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.95 linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.96 linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.95 linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.95 linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.95 linezolid
rrl 1476666 n.3009C>T non_coding_transcript_exon_variant 0.95 linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.94 linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.92 linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.92 linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.92 linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.92 linezolid
inhA 1674549 c.348G>C synonymous_variant 0.8 ethionamide
isoniazid
inhA 1674550 p.Ser117Ala missense_variant 0.8 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674579 c.378G>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 0.82 ethionamide
isoniazid
inhA 1674619 p.Pro140Ser missense_variant 0.82 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674628 p.Ser143Gly missense_variant 0.82 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 0.82 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674663 c.462G>C synonymous_variant 0.83 ethionamide
isoniazid
inhA 1674669 c.468G>C synonymous_variant 0.83 ethionamide
isoniazid
inhA 1674702 c.501G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502_504delTTGinsCTC synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517_519delAGGinsCGA synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674726 c.525G>C synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674759 c.558G>C synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674765 c.564C>T synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674771 c.570C>G synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674780 c.579T>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674789 c.588G>C synonymous_variant 0.94 ethionamide
isoniazid
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833859 c.318C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833997 c.456G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834330 c.789C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.86 pyrazinamide
rpsA 1834375 c.834G>A synonymous_variant 0.85 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.87 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.8 pyrazinamide
rpsA 1834432 c.891G>T synonymous_variant 0.8 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.83 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.83 pyrazinamide
rpsA 1834483 c.942G>A synonymous_variant 0.92 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.93 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.92 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834738 p.Glu399Asp missense_variant 1.0 pyrazinamide
rpsA 1834740 p.Thr400Ser missense_variant 1.0 pyrazinamide
rpsA 1834753 c.1212T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 1.0 pyrazinamide
rpsA 1834765 c.1224A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834774 c.1233C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834776 p.Ala412Asp missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834810 c.1269C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834813 c.1272G>C synonymous_variant 1.0 pyrazinamide
kasA 2517917 c.-198G>C upstream_gene_variant 0.8 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.91 isoniazid
rpoA 3877656 c.852T>G synonymous_variant 1.0 rifampicin
rpoA 3877665 c.843C>G synonymous_variant 1.0 rifampicin
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877674 c.834C>T synonymous_variant 1.0 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 1.0 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 1.0 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin
rpoA 3877692 c.816G>C synonymous_variant 1.0 rifampicin
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin
rpoA 3877728 c.780C>G synonymous_variant 0.9 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038890 c.1815G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038905 c.1800A>C synonymous_variant 1.0 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038980 c.1725C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039001 p.Asn568Glu missense_variant 1.0 pyrazinamide
clpC1 4039016 c.1689C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039073 c.1632C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039118 c.1587C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039124 c.1581C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039139 p.Glu522Val missense_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039166 c.1539G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039217 c.1488G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039244 c.1461G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039284 p.Asp474Val missense_variant 0.1 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039289 c.1416T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039313 c.1392C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039322 c.1383T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039328 c.1377A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039336 c.1369C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039337 c.1368A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039508 c.1197G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039553 c.1152C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039562 c.1143C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 1.0 pyrazinamide
clpC1 4039574 p.Ala377Gly missense_variant 1.0 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039586 c.1119G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039589 c.1116G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039601 c.1104G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039652 c.1053G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.85 pyrazinamide
clpC1 4039907 c.798G>A synonymous_variant 0.85 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.83 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.86 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.92 pyrazinamide