Run ID: ERR9119733
Sample name:
Date: 2024-10-03T22:22:32.616722
Number of reads: 2651480
Percentage reads mapped: 57.38
Median coverage: 60.0
Strain: lineage2.2.1
Spoligotype:
Drug-resistance: MDR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage2 | East-Asian | RD105 | 1.0 |
lineage2.2.1 | East-Asian (Beijing) | RD105;RD207;RD181 | 1.0 |
lineage2.2 | East-Asian (Beijing) | RD105;RD207 | 1.0 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | rpoB | p.Ser450Leu | Assoc w R | |
isoniazid | inhA | c.-777C>T | Assoc w R | Alias fabG1_c.-15C>T. Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance) |
p.Ile21Val | Uncertain significance | Mutation from literature | ||
katG | p.Ser140Asn | Uncertain significance | Mutation from literature | |
ethambutol | embA | c.-12C>T | Uncertain significance | Mutation from literature |
pyrazinamide | ||||
streptomycin | rrs | n.799C>T | Uncertain significance | Mutation from literature |
gid | c.102delG | Assoc w R | ||
c.87delC | Assoc w R | |||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | rrs | n.1402C>A | Uncertain significance | Mutation from literature |
n.1484G>T | Assoc w R | |||
capreomycin | rrs | n.1402C>A | Uncertain significance | Mutation from literature |
n.1484G>T | Assoc w R | |||
kanamycin | rrs | n.1402C>A | Uncertain significance | Mutation from literature |
n.1484G>T | Assoc w R | |||
cycloserine | ||||
ethionamide | inhA | c.-777C>T | Assoc w R | Alias fabG1_c.-15C>T |
ethR | p.Ala95Thr | Uncertain significance | Mutation from literature | |
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rpoB | 761155 | p.Ser450Leu | missense_variant | 0.99 | rifampicin | Assoc w R | |
rrs | 1472644 | n.799C>T | non_coding_transcript_exon_variant | 0.38 | streptomycin | Uncertain significance | Mutation from literature |
rrs | 1473247 | n.1402C>A | non_coding_transcript_exon_variant | 0.66 | amikacin | Uncertain significance | Mutation from literature |
capreomycin | Uncertain significance | Mutation from literature | |||||
kanamycin | Uncertain significance | Mutation from literature | |||||
rrs | 1473329 | n.1484G>T | non_coding_transcript_exon_variant | 0.62 | amikacin | Assoc w R | |
capreomycin | Assoc w R | ||||||
kanamycin | Assoc w R | ||||||
inhA | 1673425 | c.-777C>T | upstream_gene_variant | 1.0 | ethionamide | Assoc w R | Alias fabG1_c.-15C>T |
isoniazid | Assoc w R | Alias fabG1_c.-15C>T. Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance) | |||||
inhA | 1674262 | p.Ile21Val | missense_variant | 0.59 | isoniazid | Uncertain significance | Mutation from literature |
katG | 2155693 | p.Ser140Asn | missense_variant | 0.16 | isoniazid | Uncertain significance | Mutation from literature |
embA | 4243221 | c.-12C>T | upstream_gene_variant | 0.96 | ethambutol | Uncertain significance | Mutation from literature |
ethR | 4327831 | p.Ala95Thr | missense_variant | 1.0 | ethionamide | Uncertain significance | Mutation from literature |
gid | 4408100 | c.102delG | frameshift_variant | 0.39 | streptomycin | Assoc w R | |
gid | 4408115 | c.87delC | frameshift_variant | 0.62 | streptomycin | Assoc w R |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7419 | p.Ala40Thr | missense_variant | 0.29 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 0.98 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R | |||||
mshA | 575907 | p.Ala187Val | missense_variant | 1.0 | isoniazid | Not assoc w R |
ethionamide | Not assoc w R | |||||
ccsA | 620625 | p.Ile245Met | missense_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
Rv0565c | 657081 | c.390G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657142 | p.Arg110His | missense_variant | 1.0 | ethionamide | Uncertain significance |
rpoB | 761006 | c.1200C>G | synonymous_variant | 0.12 | rifampicin | Not assoc w R - Interim |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.12 | rifampicin | Not assoc w R - Interim |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761051 | c.1245G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761054 | c.1248G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761060 | c.1254C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761064 | p.Ala420Ser | missense_variant | 0.24 | rifampicin | Uncertain significance |
rpoB | 761088 | c.1282_1283delAGinsTC | synonymous_variant | 0.19 | rifampicin | |
rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 0.16 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.15 | rifampicin | |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 762002 | c.2196C>G | synonymous_variant | 0.14 | rifampicin | |
rpoB | 762003 | p.Asn733Gln | missense_variant | 0.14 | rifampicin | |
rpoB | 762011 | c.2205G>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 762015 | p.Glu737Gln | missense_variant | 0.13 | rifampicin | |
rpoB | 762020 | p.Glu738Asp | missense_variant | 0.14 | rifampicin | |
rpoB | 762026 | c.2220G>C | synonymous_variant | 0.16 | rifampicin | |
rpoB | 762030 | p.Thr742Ser | missense_variant | 0.16 | rifampicin | |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 762057 | p.Ile751Val | missense_variant | 0.14 | rifampicin | Uncertain significance |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.12 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.12 | rifampicin | Not assoc w R - Interim |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.13 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 762156 | p.Val784Ile | missense_variant | 0.16 | rifampicin | |
rpoB | 762162 | p.Ile786Val | missense_variant | 0.19 | rifampicin | |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762189 | p.Ile795Leu | missense_variant | 0.23 | rifampicin | |
rpoB | 762194 | c.2388G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762209 | c.2403C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762212 | c.2406G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762218 | c.2412T>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 762245 | c.2439G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762254 | c.2448T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.12 | rifampicin | Not assoc w R - Interim |
rpoB | 762879 | p.Met1025Leu | missense_variant | 0.21 | rifampicin | Uncertain significance |
rpoC | 762896 | c.-474G>C | upstream_gene_variant | 0.27 | rifampicin | |
rpoB | 762899 | c.3093G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 762917 | c.-453C>T | upstream_gene_variant | 0.32 | rifampicin | |
rpoB | 762923 | c.3117C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 762926 | c.-444C>G | upstream_gene_variant | 0.32 | rifampicin | |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 762959 | c.3153G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 762971 | c.-399G>C | upstream_gene_variant | 0.22 | rifampicin | |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.12 | rifampicin | |
rpoB | 763031 | c.3225T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 763043 | c.-327G>C | upstream_gene_variant | 0.15 | rifampicin | |
rpoB | 763053 | c.3247T>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 763058 | c.-312C>G | upstream_gene_variant | 0.14 | rifampicin | |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 763074 | p.Thr1090Val | missense_variant | 0.14 | rifampicin | |
rpoB | 763077 | p.Val1091Pro | missense_variant | 0.14 | rifampicin | |
rpoC | 763082 | c.-288C>A | upstream_gene_variant | 0.13 | rifampicin | |
rpoB | 763094 | c.3288G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 763501 | p.Asp44Glu | missense_variant | 0.19 | rifampicin | Uncertain significance |
rpoC | 763517 | p.Lys50Arg | missense_variant | 0.22 | rifampicin | |
rpoC | 763528 | c.159G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 763534 | c.165T>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 763550 | p.Tyr61Asn | missense_variant | 0.36 | rifampicin | |
rpoC | 763555 | c.186C>T | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 763615 | c.246G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 763618 | c.249C>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 763633 | c.264T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 763660 | c.291T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 763666 | c.297G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 763699 | c.330G>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 763708 | c.339G>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 763711 | c.342G>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.14 | rifampicin | |
rpoC | 763729 | c.360G>C | synonymous_variant | 0.14 | rifampicin | |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764581 | c.1212T>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764582 | p.Leu405Met | missense_variant | 0.22 | rifampicin | |
rpoC | 764605 | c.1236G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764611 | c.1242G>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 764632 | c.1263T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 764644 | c.1275G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764662 | c.1293G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764695 | c.1326T>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 764706 | p.Leu446Gln | missense_variant | 0.39 | rifampicin | Uncertain significance |
rpoC | 764716 | c.1347G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 764722 | c.1353G>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 764746 | c.1377G>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 764759 | p.Asn464Asp | missense_variant | 0.26 | rifampicin | |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764780 | c.1411_1413delAGCinsTCG | synonymous_variant | 0.13 | rifampicin | |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 776182 | p.Asp767Asn | missense_variant | 1.0 | bedaquiline | Not assoc w R |
clofazimine | Not assoc w R | |||||
mmpS5 | 778979 | c.-74G>T | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Uncertain significance | |||||
mmpS5 | 779615 | c.-710C>G | upstream_gene_variant | 1.0 | bedaquiline | |
clofazimine | ||||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781796 | p.Met79Ile | missense_variant | 0.13 | streptomycin | |
rpsL | 781802 | c.243G>C | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781814 | c.255C>T | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781817 | c.258G>T | synonymous_variant | 0.2 | streptomycin | |
rpsL | 781829 | c.270G>T | synonymous_variant | 0.21 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.21 | streptomycin | |
rpsL | 781835 | c.276T>C | synonymous_variant | 0.21 | streptomycin | Not assoc w R - Interim |
rpsL | 781838 | c.279G>C | synonymous_variant | 0.22 | streptomycin | |
rpsL | 781859 | c.300T>C | synonymous_variant | 0.24 | streptomycin | Not assoc w R - Interim |
rpsL | 781860 | p.Ser101Thr | missense_variant | 0.24 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.24 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.24 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.24 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.23 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781901 | c.342C>T | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781907 | c.348T>C | synonymous_variant | 0.18 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.13 | streptomycin | Uncertain significance |
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
Rv1258c | 1406760 | c.580_581insC | frameshift_variant | 1.0 | streptomycin | Uncertain significance |
pyrazinamide | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.18 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472078 | n.233C>T | non_coding_transcript_exon_variant | 0.22 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472102 | n.257G>A | non_coding_transcript_exon_variant | 0.37 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472106 | n.261G>A | non_coding_transcript_exon_variant | 0.38 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472107 | n.262A>G | non_coding_transcript_exon_variant | 0.38 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.38 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472112 | n.267C>T | non_coding_transcript_exon_variant | 0.38 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472113 | n.268T>C | non_coding_transcript_exon_variant | 0.39 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472148 | n.303T>C | non_coding_transcript_exon_variant | 0.58 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.57 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472172 | n.327T>C | non_coding_transcript_exon_variant | 0.65 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472225 | n.380C>A | non_coding_transcript_exon_variant | 0.6 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472251 | n.406G>A | non_coding_transcript_exon_variant | 0.47 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472286 | n.441C>G | non_coding_transcript_exon_variant | 0.14 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472344 | n.499C>T | non_coding_transcript_exon_variant | 0.31 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472400 | n.555C>T | non_coding_transcript_exon_variant | 0.33 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472416 | n.571C>T | non_coding_transcript_exon_variant | 0.33 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472422 | n.577T>C | non_coding_transcript_exon_variant | 0.3 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472558 | n.713G>A | non_coding_transcript_exon_variant | 0.4 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472569 | n.724G>A | non_coding_transcript_exon_variant | 0.38 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472581 | n.736A>C | non_coding_transcript_exon_variant | 0.39 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472582 | n.737G>A | non_coding_transcript_exon_variant | 0.39 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472583 | n.738T>C | non_coding_transcript_exon_variant | 0.39 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472584 | n.739A>T | non_coding_transcript_exon_variant | 0.39 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472597 | n.752G>A | non_coding_transcript_exon_variant | 0.4 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472607 | n.762G>A | non_coding_transcript_exon_variant | 0.41 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472655 | n.810G>T | non_coding_transcript_exon_variant | 0.26 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472660 | n.815T>C | non_coding_transcript_exon_variant | 0.24 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472661 | n.816A>G | non_coding_transcript_exon_variant | 0.25 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472673 | n.828T>A | non_coding_transcript_exon_variant | 0.25 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472674 | n.829T>C | non_coding_transcript_exon_variant | 0.25 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472675 | n.830T>C | non_coding_transcript_exon_variant | 0.25 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472677 | n.832C>A | non_coding_transcript_exon_variant | 0.25 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472682 | n.837T>A | non_coding_transcript_exon_variant | 0.25 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472683 | n.838T>C | non_coding_transcript_exon_variant | 0.25 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472687 | n.842A>T | non_coding_transcript_exon_variant | 0.28 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472697 | n.852T>C | non_coding_transcript_exon_variant | 0.43 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472713 | n.868T>C | non_coding_transcript_exon_variant | 0.49 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472714 | n.869A>G | non_coding_transcript_exon_variant | 0.5 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472790 | n.945T>C | non_coding_transcript_exon_variant | 0.49 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472895 | n.1050C>T | non_coding_transcript_exon_variant | 0.33 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472952 | n.1107T>C | non_coding_transcript_exon_variant | 0.62 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472955 | n.1110C>T | non_coding_transcript_exon_variant | 0.61 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472956 | n.1111T>C | non_coding_transcript_exon_variant | 0.63 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472957 | n.1112C>T | non_coding_transcript_exon_variant | 0.63 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472973 | n.1128A>G | non_coding_transcript_exon_variant | 0.68 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472987 | n.1142G>A | non_coding_transcript_exon_variant | 0.67 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472989 | n.1144G>A | non_coding_transcript_exon_variant | 0.67 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472990 | n.1145A>G | non_coding_transcript_exon_variant | 0.66 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473035 | n.1190G>A | non_coding_transcript_exon_variant | 0.58 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473055 | n.1210C>T | non_coding_transcript_exon_variant | 0.58 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473056 | n.1211A>T | non_coding_transcript_exon_variant | 0.59 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473066 | n.1221A>G | non_coding_transcript_exon_variant | 0.66 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473099 | n.1254T>A | non_coding_transcript_exon_variant | 0.65 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473100 | n.1255G>A | non_coding_transcript_exon_variant | 0.65 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.65 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.66 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 0.64 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.64 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473121 | n.1276T>C | non_coding_transcript_exon_variant | 0.71 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473122 | n.1277T>A | non_coding_transcript_exon_variant | 0.71 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473127 | n.1282G>A | non_coding_transcript_exon_variant | 0.72 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.73 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.7 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473252 | n.1407T>C | non_coding_transcript_exon_variant | 0.69 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.7 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473283 | n.1438T>C | non_coding_transcript_exon_variant | 0.68 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.67 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473292 | n.1447_1449delGGAinsTGGG | non_coding_transcript_exon_variant | 0.69 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 0.7 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473315 | n.1470T>C | non_coding_transcript_exon_variant | 0.67 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473316 | n.1471C>T | non_coding_transcript_exon_variant | 0.65 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrl | 1473832 | n.175C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473833 | n.176_177insT | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473844 | n.187C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473870 | n.213G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473871 | n.214T>C | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473876 | n.219G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473887 | n.230T>C | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473888 | n.231T>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473916 | n.259C>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474179 | n.522C>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474183 | n.526T>C | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474184 | n.527C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474186 | n.529A>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474201 | n.544T>C | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474202 | n.545T>A | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1474218 | n.561T>A | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474252 | n.595T>A | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474253 | n.596A>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474488 | n.831G>T | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474497 | n.840G>A | non_coding_transcript_exon_variant | 0.54 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474506 | n.849C>T | non_coding_transcript_exon_variant | 0.59 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474516 | n.859C>A | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474537 | n.880G>A | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474626 | n.969T>C | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474627 | n.970G>A | non_coding_transcript_exon_variant | 0.59 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474636 | n.979A>T | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474637 | n.980C>T | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474638 | n.981C>G | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>C | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474660 | n.1003G>A | non_coding_transcript_exon_variant | 0.63 | capreomycin | |
linezolid | ||||||
rrl | 1474672 | n.1015C>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474673 | n.1016T>C | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474676 | n.1019T>C | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474690 | n.1033C>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474709 | n.1053_1056delTGGT | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474717 | n.1060_1061insGTGAG | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
linezolid | ||||||
rrl | 1474734 | n.1077G>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474753 | n.1097delC | non_coding_transcript_exon_variant | 0.54 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474779 | n.1122G>A | non_coding_transcript_exon_variant | 0.51 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474782 | n.1125G>A | non_coding_transcript_exon_variant | 0.5 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1474790 | n.1133C>T | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>G | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474827 | n.1170C>T | non_coding_transcript_exon_variant | 0.51 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474830 | n.1173A>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474832 | n.1175A>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474869 | n.1212G>C | non_coding_transcript_exon_variant | 0.59 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474904 | n.1247G>C | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474905 | n.1248T>C | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474913 | n.1256T>C | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474938 | n.1281G>A | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1475508 | n.1851A>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475517 | n.1860C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475538 | n.1881T>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475539 | n.1882A>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475544 | n.1887A>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475545 | n.1888T>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475548 | n.1891C>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1475549 | n.1892T>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1475550 | n.1893A>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475562 | n.1905C>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1475573 | n.1916G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475616 | n.1959A>C | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1475618 | n.1961C>A | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1475624 | n.1967G>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1475626 | n.1969T>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1475634 | n.1977G>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1475637 | n.1982delC | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1475649 | n.1992A>G | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475655 | n.1998T>G | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475692 | n.2035G>C | non_coding_transcript_exon_variant | 0.55 | capreomycin | |
linezolid | ||||||
rrl | 1475740 | n.2083G>C | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475747 | n.2090A>G | non_coding_transcript_exon_variant | 0.66 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475753 | n.2096C>G | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475758 | n.2101A>G | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
linezolid | ||||||
rrl | 1475760 | n.2103C>A | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
linezolid | ||||||
rrl | 1475767 | n.2110G>T | non_coding_transcript_exon_variant | 0.6 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475769 | n.2112T>C | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
linezolid | ||||||
rrl | 1475775 | n.2118G>T | non_coding_transcript_exon_variant | 0.66 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475781 | n.2124T>C | non_coding_transcript_exon_variant | 0.66 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475788 | n.2131C>G | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475883 | n.2226A>C | non_coding_transcript_exon_variant | 0.74 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475897 | n.2240T>C | non_coding_transcript_exon_variant | 0.71 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475898 | n.2241A>G | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475899 | n.2242G>A | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475943 | n.2286G>A | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475952 | n.2295A>G | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475970 | n.2313C>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.45 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476001 | n.2344T>C | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476165 | n.2508T>G | non_coding_transcript_exon_variant | 0.34 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476194 | n.2537A>G | non_coding_transcript_exon_variant | 0.42 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476200 | n.2543A>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476201 | n.2544C>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476251 | n.2594T>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476252 | n.2595T>G | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476256 | n.2599A>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.24 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476359 | n.2702C>G | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476381 | n.2724G>C | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.66 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476466 | n.2809C>T | non_coding_transcript_exon_variant | 0.56 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476506 | n.2849T>C | non_coding_transcript_exon_variant | 0.39 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476515 | n.2858C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476517 | n.2860C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476523 | n.2866T>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476524 | n.2867C>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476525 | n.2868A>G | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476536 | n.2879G>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476539 | n.2882A>G | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476540 | n.2883C>G | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476567 | n.2910C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476585 | n.2928A>G | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476586 | n.2929C>T | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.23 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476613 | n.2956G>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1476614 | n.2957A>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476629 | n.2972C>A | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476630 | n.2973A>G | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476631 | n.2974G>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rpsA | 1833676 | c.135A>G | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833679 | c.138G>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833694 | c.153G>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833697 | c.156C>G | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833721 | c.180A>G | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833862 | c.321G>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1833886 | c.345C>G | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833893 | p.Ala118Lys | missense_variant | 0.14 | pyrazinamide | |
rpsA | 1833896 | p.Leu119Ile | missense_variant | 0.14 | pyrazinamide | |
rpsA | 1833905 | p.Lys122Glu | missense_variant | 0.14 | pyrazinamide | |
rpsA | 1833912 | p.Glu124Gly | missense_variant | 0.13 | pyrazinamide | |
rpsA | 1833915 | p.Ala125Val | missense_variant | 0.13 | pyrazinamide | Uncertain significance |
rpsA | 1833921 | p.Lys127Thr | missense_variant | 0.14 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1833955 | c.414G>C | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833970 | c.429G>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833994 | c.453G>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833997 | c.456G>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834009 | c.468C>T | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1834012 | c.471G>C | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834015 | c.474G>C | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834024 | c.483G>C | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834034 | p.Ile165Val | missense_variant | 0.38 | pyrazinamide | |
rpsA | 1834069 | c.528G>C | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1834093 | c.552G>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834099 | c.558C>G | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834108 | c.567C>G | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834114 | c.573G>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834123 | c.582C>G | synonymous_variant | 0.12 | pyrazinamide | |
rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834210 | c.669C>T | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834219 | c.678C>G | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834231 | c.690T>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834234 | c.693G>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834243 | c.702G>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834246 | c.705G>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.27 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834294 | c.753G>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834297 | c.756C>G | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834298 | p.Gln253Glu | missense_variant | 0.16 | pyrazinamide | |
rpsA | 1834303 | c.762T>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1834307 | p.Asp256Asn | missense_variant | 0.15 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.18 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834354 | c.813G>T | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834357 | c.816T>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834360 | c.819G>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834361 | c.820T>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.15 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834378 | c.837T>G | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834384 | c.843A>G | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834395 | p.Arg285Gln | missense_variant | 0.16 | pyrazinamide | |
rpsA | 1834408 | c.867C>G | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.13 | pyrazinamide | |
rpsA | 1834427 | p.Ile296Val | missense_variant | 0.13 | pyrazinamide | Uncertain significance |
rpsA | 1834432 | c.891G>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834451 | c.910_912delTTGinsCTT | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834456 | c.915T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834486 | p.Glu315Asp | missense_variant | 0.15 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.16 | pyrazinamide | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Not assoc w R |
katG | 2155643 | p.Lys157Gln | missense_variant | 0.12 | isoniazid | |
katG | 2155655 | p.Lys153Gln | missense_variant | 0.13 | isoniazid | Uncertain significance |
katG | 2155671 | c.441G>C | synonymous_variant | 0.14 | isoniazid | |
katG | 2155674 | c.438G>C | synonymous_variant | 0.15 | isoniazid | |
katG | 2155680 | c.432G>C | synonymous_variant | 0.14 | isoniazid | |
katG | 2155689 | c.421_423delTTGinsCTC | synonymous_variant | 0.16 | isoniazid | Not assoc w R - Interim |
katG | 2155716 | c.396T>C | synonymous_variant | 0.24 | isoniazid | |
katG | 2155722 | c.390G>C | synonymous_variant | 0.2 | isoniazid | |
katG | 2155728 | c.384G>C | synonymous_variant | 0.16 | isoniazid | |
katG | 2155743 | c.369G>C | synonymous_variant | 0.13 | isoniazid | |
katG | 2155766 | p.His116Tyr | missense_variant | 0.16 | isoniazid | Uncertain significance |
katG | 2155776 | c.336C>G | synonymous_variant | 0.15 | isoniazid | |
katG | 2155785 | c.327T>C | synonymous_variant | 0.16 | isoniazid | |
katG | 2156591 | c.-480T>G | upstream_gene_variant | 0.29 | isoniazid | Uncertain significance |
PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
ribD | 2987172 | p.Ser112Gly | missense_variant | 1.0 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
Rv3236c | 3612813 | p.Thr102Ala | missense_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
mtrB | 3626562 | p.Pro18Ser | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
rpoA | 3877949 | p.Thr187Ala | missense_variant | 0.9 | rifampicin | Uncertain significance |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4038794 | c.1909_1911delAGCinsTCG | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4038801 | p.Tyr635Phe | missense_variant | 0.13 | pyrazinamide | |
clpC1 | 4038810 | p.Gln632Pro | missense_variant | 0.13 | pyrazinamide | |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4038815 | c.1890G>C | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4038826 | p.Ile627Val | missense_variant | 0.12 | pyrazinamide | |
clpC1 | 4039875 | p.Asn277Arg | missense_variant | 0.14 | pyrazinamide | |
clpC1 | 4039889 | c.816G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039901 | c.804C>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039904 | c.801A>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039925 | c.780C>T | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039934 | c.771G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039940 | c.765G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039946 | c.759A>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039949 | c.756G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039955 | c.750G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039958 | c.747G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4040000 | p.His235Lys | missense_variant | 0.24 | pyrazinamide | |
clpC1 | 4040003 | c.702G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4040010 | p.Ala232Asp | missense_variant | 0.3 | pyrazinamide | Uncertain significance |
clpC1 | 4040015 | c.690G>C | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.36 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4040063 | c.642G>C | synonymous_variant | 0.39 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040066 | c.639G>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4040069 | c.636G>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4040087 | c.618G>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4040090 | c.615T>C | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040093 | c.612C>G | synonymous_variant | 0.27 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040117 | c.588A>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4040129 | c.576C>G | synonymous_variant | 0.12 | pyrazinamide | |
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4243460 | c.228C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
aftB | 4267647 | p.Asp397Gly | missense_variant | 1.0 | ethambutol | Not assoc w R |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
gid | 4407588 | c.615A>G | synonymous_variant | 1.0 | streptomycin | Not assoc w R |
gid | 4407927 | p.Glu92Asp | missense_variant | 1.0 | streptomycin | Not assoc w R |