Run ID: ERR9787336
Sample name:
Date: 2024-04-15T07:21:11.389677
Number of reads: 2566844
Percentage reads mapped: 74.81
Median coverage: 114.0
Strain: lineage6.1.3
Spoligotype:
Drug-resistance: RR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage6.1.3 | West-Africa 2 | RD702 | 0.71 |
lineage6 | West-Africa 2 | RD702 | 1.0 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | rpoB | p.Ser428Cys | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
p.Ser450Asn | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB | ||
isoniazid | ||||
ethambutol | embC | p.Ala307Thr | Uncertain significance | Mutation from literature |
pyrazinamide | ||||
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rpoB | 761088 | p.Ser428Cys | missense_variant | 0.12 | rifampicin | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
rpoB | 761154 | p.Ser450Asn | missense_variant | 0.13 | rifampicin | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
embC | 4240781 | p.Ala307Thr | missense_variant | 1.0 | ethambutol | Uncertain significance | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
gyrB | 6446 | p.Ala403Ser | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Uncertain significance | |||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 8493 | p.Leu398Phe | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9143 | c.1842T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
Rv0010c | 13460 | c.99T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R |
Rv0010c | 13482 | p.Ala26Val | missense_variant | 1.0 | isoniazid | Not assoc w R |
fgd1 | 491668 | p.Lys296Glu | missense_variant | 1.0 | clofazimine | Uncertain significance |
pretomanid | ||||||
delamanid | Uncertain significance | |||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
Rv0565c | 656054 | p.Arg473* | stop_gained | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 656432 | p.Gly347Ser | missense_variant | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 657578 | c.-108T>C | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657686 | c.-216C>G | upstream_gene_variant | 1.0 | ethionamide | |
rpoB | 760490 | c.684C>G | synonymous_variant | 0.13 | rifampicin | |
rpoB | 760855 | p.Thr350Ile | missense_variant | 0.98 | rifampicin | Uncertain significance |
rpoB | 760969 | p.Ser388Leu | missense_variant | 0.95 | rifampicin | Not assoc w R |
rpoB | 761132 | c.1326G>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 761168 | c.1362C>G | synonymous_variant | 0.14 | rifampicin | |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>G | synonymous_variant | 0.16 | rifampicin | |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 761201 | c.1395G>A | synonymous_variant | 0.15 | rifampicin | |
rpoB | 761204 | c.1398C>A | synonymous_variant | 0.16 | rifampicin | |
rpoB | 761207 | c.1401C>T | synonymous_variant | 0.15 | rifampicin | |
rpoB | 761723 | p.Glu639Asp | missense_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 762170 | c.2364C>G | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 762179 | c.2373C>T | synonymous_variant | 0.13 | rifampicin | |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 762218 | c.2412T>C | synonymous_variant | 0.12 | rifampicin | |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 762254 | c.2448T>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.13 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.13 | rifampicin | |
rpoB | 762879 | p.Met1025Leu | missense_variant | 0.16 | rifampicin | Uncertain significance |
rpoB | 762899 | c.3093G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 762920 | c.3114C>T | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 762923 | c.3117C>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762959 | c.3153G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 762962 | c.3156C>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 762983 | c.-387C>T | upstream_gene_variant | 0.21 | rifampicin | |
rpoB | 762989 | c.3183G>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 762995 | c.3189G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 762998 | c.-372G>A | upstream_gene_variant | 0.2 | rifampicin | |
rpoB | 763004 | c.3198G>A | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 763053 | c.3247T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 763074 | p.Thr1090Val | missense_variant | 0.17 | rifampicin | |
rpoC | 763079 | c.-291C>G | upstream_gene_variant | 0.17 | rifampicin | |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 763094 | c.3288G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 763103 | c.-267G>C | upstream_gene_variant | 0.17 | rifampicin | |
rpoC | 763124 | c.-246C>T | upstream_gene_variant | 0.16 | rifampicin | |
rpoC | 763139 | c.-231C>T | upstream_gene_variant | 0.12 | rifampicin | |
rpoC | 763142 | c.-228C>G | upstream_gene_variant | 0.12 | rifampicin | |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 763558 | c.189C>T | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 764371 | c.1002G>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 764387 | c.1018T>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036A>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 764410 | c.1041G>C | synonymous_variant | 0.13 | rifampicin | |
rpoC | 764428 | c.1059G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 764435 | c.1066_1068delAGGinsCA | frameshift_variant&missense_variant | 0.14 | rifampicin | |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.14 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.14 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.14 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764503 | c.1134G>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 764510 | c.1141C>T | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764548 | c.1179G>T | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.14 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 764572 | c.1203G>C | synonymous_variant | 0.13 | rifampicin | |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 764577 | p.Ser403Cys | missense_variant | 0.12 | rifampicin | Uncertain significance |
rpoC | 764593 | c.1224C>T | synonymous_variant | 0.13 | rifampicin | |
rpoC | 764602 | c.1233C>T | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764605 | c.1236G>T | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764626 | c.1257C>T | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764641 | c.1272C>T | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764644 | c.1275G>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>C | synonymous_variant | 0.14 | rifampicin | |
rpoC | 764662 | c.1293G>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764668 | c.1299C>T | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764677 | c.1308C>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764680 | c.1311G>A | synonymous_variant | 0.14 | rifampicin | |
rpoC | 764731 | c.1362G>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764758 | c.1389C>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 764780 | c.1411_1412delAGinsTC | synonymous_variant | 0.17 | rifampicin | |
rpoC | 764791 | c.1422C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764803 | c.1434C>G | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764809 | c.1440C>G | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764812 | c.1443C>G | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764824 | c.1455T>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 765820 | c.2451G>C | synonymous_variant | 0.13 | rifampicin | |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 765871 | c.2502T>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 765875 | p.Val836Ile | missense_variant | 0.17 | rifampicin | Uncertain significance |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.16 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 765904 | c.2535C>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 765907 | c.2538G>T | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 766231 | c.2862T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 777761 | c.720G>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.14 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.13 | streptomycin | |
rplC | 800232 | c.-577G>T | upstream_gene_variant | 0.99 | linezolid | |
Rv1129c | 1254221 | p.Gln105Pro | missense_variant | 1.0 | moxifloxacin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 1.0 | moxifloxacin | Not assoc w R |
levofloxacin | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
fbiC | 1302899 | c.-32A>G | upstream_gene_variant | 0.99 | clofazimine | Uncertain significance |
pretomanid | ||||||
delamanid | Uncertain significance | |||||
Rv1258c | 1406685 | p.Val219Ala | missense_variant | 1.0 | streptomycin | Uncertain significance |
isoniazid | Uncertain significance | |||||
pyrazinamide | Uncertain significance | |||||
embR | 1416633 | p.Leu239Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
embR | 1417554 | c.-207C>G | upstream_gene_variant | 1.0 | ethambutol | |
atpE | 1461251 | c.207G>T | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471978 | n.133C>T | non_coding_transcript_exon_variant | 0.14 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471979 | n.134T>C | non_coding_transcript_exon_variant | 0.13 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471986 | n.141C>T | non_coding_transcript_exon_variant | 0.13 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472023 | n.178G>C | non_coding_transcript_exon_variant | 0.18 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472030 | n.185G>C | non_coding_transcript_exon_variant | 0.19 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472031 | n.186G>A | non_coding_transcript_exon_variant | 0.19 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472032 | n.187G>A | non_coding_transcript_exon_variant | 0.19 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472033 | n.188A>C | non_coding_transcript_exon_variant | 0.19 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 0.19 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472040 | n.195T>G | non_coding_transcript_exon_variant | 0.19 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472041 | n.196C>T | non_coding_transcript_exon_variant | 0.18 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472043 | n.198T>G | non_coding_transcript_exon_variant | 0.2 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.2 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472057 | n.212C>A | non_coding_transcript_exon_variant | 0.2 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472062 | n.217G>T | non_coding_transcript_exon_variant | 0.21 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472068 | n.223T>C | non_coding_transcript_exon_variant | 0.22 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472070 | n.225G>A | non_coding_transcript_exon_variant | 0.22 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472106 | n.261G>A | non_coding_transcript_exon_variant | 0.3 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.3 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472148 | n.303T>C | non_coding_transcript_exon_variant | 0.29 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.28 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472172 | n.327T>C | non_coding_transcript_exon_variant | 0.31 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472225 | n.380C>G | non_coding_transcript_exon_variant | 0.35 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472251 | n.406G>A | non_coding_transcript_exon_variant | 0.32 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472285 | n.440A>G | non_coding_transcript_exon_variant | 0.23 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472286 | n.441C>A | non_coding_transcript_exon_variant | 0.24 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472288 | n.443A>T | non_coding_transcript_exon_variant | 0.24 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472289 | n.444T>C | non_coding_transcript_exon_variant | 0.24 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472297 | n.453_465delGTCCGGGTTCTCT | non_coding_transcript_exon_variant | 0.25 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472313 | n.468delGinsAA | non_coding_transcript_exon_variant | 0.23 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472315 | n.470T>G | non_coding_transcript_exon_variant | 0.23 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472326 | n.481T>A | non_coding_transcript_exon_variant | 0.23 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472328 | n.483G>T | non_coding_transcript_exon_variant | 0.23 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472330 | n.485G>T | non_coding_transcript_exon_variant | 0.23 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472416 | n.571C>T | non_coding_transcript_exon_variant | 0.25 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472422 | n.577T>C | non_coding_transcript_exon_variant | 0.25 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Uncertain significance | |||||
rrs | 1472425 | n.580T>C | non_coding_transcript_exon_variant | 0.25 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472435 | n.590T>C | non_coding_transcript_exon_variant | 0.25 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472437 | n.592T>A | non_coding_transcript_exon_variant | 0.25 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472446 | n.601T>A | non_coding_transcript_exon_variant | 0.23 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472450 | n.605A>G | non_coding_transcript_exon_variant | 0.22 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472451 | n.606C>G | non_coding_transcript_exon_variant | 0.21 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472456 | n.611T>C | non_coding_transcript_exon_variant | 0.21 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472460 | n.615T>C | non_coding_transcript_exon_variant | 0.2 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472461 | n.616G>C | non_coding_transcript_exon_variant | 0.21 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472462 | n.617T>C | non_coding_transcript_exon_variant | 0.21 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472467 | n.622G>T | non_coding_transcript_exon_variant | 0.24 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472473 | n.628G>T | non_coding_transcript_exon_variant | 0.25 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472486 | n.641A>G | non_coding_transcript_exon_variant | 0.28 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472489 | n.644A>T | non_coding_transcript_exon_variant | 0.28 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472497 | n.652G>T | non_coding_transcript_exon_variant | 0.31 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472530 | n.685G>A | non_coding_transcript_exon_variant | 0.35 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472580 | n.735C>A | non_coding_transcript_exon_variant | 0.36 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472597 | n.752G>A | non_coding_transcript_exon_variant | 0.34 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472612 | n.767G>T | non_coding_transcript_exon_variant | 0.32 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472682 | n.837T>A | non_coding_transcript_exon_variant | 0.26 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472683 | n.838T>C | non_coding_transcript_exon_variant | 0.26 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472836 | n.991G>A | non_coding_transcript_exon_variant | 0.25 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472840 | n.995A>C | non_coding_transcript_exon_variant | 0.25 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472844 | n.999C>A | non_coding_transcript_exon_variant | 0.24 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472845 | n.1000G>A | non_coding_transcript_exon_variant | 0.25 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472847 | n.1002G>C | non_coding_transcript_exon_variant | 0.25 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472849 | n.1004C>G | non_coding_transcript_exon_variant | 0.25 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472850 | n.1005T>C | non_coding_transcript_exon_variant | 0.24 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472855 | n.1011_1012insGT | non_coding_transcript_exon_variant | 0.26 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472861 | n.1016_1018delGTTinsC | non_coding_transcript_exon_variant | 0.26 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472873 | n.1028C>T | non_coding_transcript_exon_variant | 0.3 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472875 | n.1030T>G | non_coding_transcript_exon_variant | 0.3 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472880 | n.1035G>A | non_coding_transcript_exon_variant | 0.31 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472953 | n.1108G>A | non_coding_transcript_exon_variant | 0.4 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472957 | n.1112C>T | non_coding_transcript_exon_variant | 0.39 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.39 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.4 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473026 | n.1181T>C | non_coding_transcript_exon_variant | 0.4 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473088 | n.1243A>G | non_coding_transcript_exon_variant | 0.43 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473100 | n.1255G>A | non_coding_transcript_exon_variant | 0.42 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.4 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 0.4 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.4 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473121 | n.1276T>C | non_coding_transcript_exon_variant | 0.37 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1473123 | n.1278A>T | non_coding_transcript_exon_variant | 0.39 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473173 | n.1328C>T | non_coding_transcript_exon_variant | 0.44 | streptomycin | Not assoc w R |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.34 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.3 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473291 | n.1446_1447insT | non_coding_transcript_exon_variant | 0.31 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 0.28 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrl | 1473731 | n.74T>A | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473756 | n.99G>T | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473757 | n.100T>G | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473768 | n.111A>G | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1473770 | n.113T>G | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473822 | n.165A>G | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473832 | n.175C>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473833 | n.176_177insT | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473844 | n.187C>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473870 | n.213G>A | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473871 | n.214T>C | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473876 | n.219G>A | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473887 | n.230delTinsCA | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>G | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473916 | n.259C>A | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474174 | n.517A>G | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474183 | n.526T>C | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474184 | n.527C>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474186 | n.529A>G | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474201 | n.544T>C | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474218 | n.561T>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474266 | n.609T>C | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474269 | n.612C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474288 | n.631_634delCCTTinsGTGCCAC | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1474294 | n.638_646delCTCTCCGGA | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1474306 | n.649A>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1474310 | n.655dupG | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1474348 | n.691C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474351 | n.694G>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474353 | n.696A>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474359 | n.702C>G | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474387 | n.730C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474402 | n.745T>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474413 | n.756A>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1474414 | n.757C>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1474415 | n.758C>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474416 | n.761_784delCACGCGCATACGCGCGTGTGAATA | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1474444 | n.787G>C | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1474454 | n.797G>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474496 | n.839C>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474497 | n.840G>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474506 | n.849C>G | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474507 | n.850G>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474537 | n.880G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474626 | n.969T>C | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474627 | n.970G>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474638 | n.981C>G | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474664 | n.1007G>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474666 | n.1009T>G | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474670 | n.1013C>G | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474673 | n.1016T>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474676 | n.1019T>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474679 | n.1022G>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474684 | n.1027T>C | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474687 | n.1030C>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474710 | n.1053T>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474711 | n.1054G>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474716 | n.1059_1060delAAinsGAG | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474734 | n.1077G>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474749 | n.1092C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474753 | n.1097delC | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474803 | n.1146G>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>G | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474824 | n.1167A>G | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474825 | n.1168G>A | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1474827 | n.1170C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474831 | n.1174A>C | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474837 | n.1180A>G | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1474896 | n.1239A>G | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474903 | n.1246T>C | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474904 | n.1247G>C | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474913 | n.1256T>C | non_coding_transcript_exon_variant | 0.13 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475538 | n.1881T>A | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475539 | n.1882A>T | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475545 | n.1888T>G | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475550 | n.1893A>G | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475555 | n.1898T>C | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1475602 | n.1945G>C | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475627 | n.1970G>T | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1475639 | n.1982C>G | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475649 | n.1992A>G | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475655 | n.1998T>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475699 | n.2042C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475735 | n.2078T>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475753 | n.2096C>G | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475758 | n.2101A>G | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1475760 | n.2103C>G | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1475762 | n.2105G>C | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1475763 | n.2106C>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475764 | n.2107A>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2108A>C | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1475769 | n.2113_2114insCG | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1475775 | n.2118G>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475791 | n.2134A>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475883 | n.2226A>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475884 | n.2227A>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475892 | n.2235A>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475897 | n.2240T>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475916 | n.2259C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475975 | n.2318C>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476030 | n.2373A>G | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476032 | n.2375C>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1476034 | n.2377C>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476035 | n.2378G>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476044 | n.2387T>G | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476058 | n.2401T>C | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476076 | n.2419A>G | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476088 | n.2431A>C | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476099 | n.2442A>G | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476103 | n.2446C>A | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476105 | n.2450delA | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1476110 | n.2453G>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476160 | n.2503T>C | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476194 | n.2537A>G | non_coding_transcript_exon_variant | 0.35 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476200 | n.2543A>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476201 | n.2544C>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476221 | n.2564T>C | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476251 | n.2594T>A | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476252 | n.2595T>G | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476256 | n.2599A>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.36 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476297 | n.2640C>G | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476298 | n.2641C>G | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476300 | n.2643G>A | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476301 | n.2644A>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476309 | n.2652G>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476524 | n.2867C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1476525 | n.2868A>G | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476539 | n.2882A>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476540 | n.2883C>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476585 | n.2928A>G | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476614 | n.2957A>T | non_coding_transcript_exon_variant | 0.13 | capreomycin | |
linezolid | ||||||
inhA | 1674434 | p.Val78Ala | missense_variant | 1.0 | ethionamide | Uncertain significance |
isoniazid | Not assoc w R | |||||
rpsA | 1833799 | c.258C>G | synonymous_variant | 0.13 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.13 | pyrazinamide | |
rpsA | 1833811 | c.270G>C | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833859 | c.318C>G | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833871 | c.330G>A | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.13 | pyrazinamide | |
rpsA | 1833886 | c.345C>G | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833919 | c.378C>T | synonymous_variant | 0.13 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833920 | p.Lys127Arg | missense_variant | 0.14 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833931 | c.390C>G | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833949 | c.408T>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1833952 | c.411C>T | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1833964 | c.423C>T | synonymous_variant | 0.17 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833970 | c.429G>T | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834015 | c.474G>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834034 | p.Ile165Val | missense_variant | 0.18 | pyrazinamide | |
rpsA | 1834093 | c.552G>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834105 | c.564C>T | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834151 | c.610_612delAATinsCC | frameshift_variant&missense_variant | 0.15 | pyrazinamide | Uncertain significance |
rpsA | 1834154 | c.613_615delAACinsCG | frameshift_variant&missense_variant | 0.14 | pyrazinamide | Uncertain significance |
rpsA | 1834157 | c.616T>C | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1834162 | c.621A>G | synonymous_variant | 0.14 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834165 | c.624A>G | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1834167 | c.628_629delAC | frameshift_variant | 0.15 | pyrazinamide | Uncertain significance |
rpsA | 1834172 | c.631_632insGG | frameshift_variant | 0.14 | pyrazinamide | Uncertain significance |
rpsA | 1834177 | c.636A>C | synonymous_variant | 0.15 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834186 | c.645C>G | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834189 | c.648G>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834213 | c.672G>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834234 | c.693G>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.17 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834264 | c.723G>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834279 | c.738C>T | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834298 | p.Gln253Glu | missense_variant | 0.17 | pyrazinamide | |
rpsA | 1834303 | c.762T>G | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834307 | p.Asp256Asn | missense_variant | 0.17 | pyrazinamide | |
rpsA | 1834327 | c.786G>T | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834340 | p.Met267Leu | missense_variant | 0.19 | pyrazinamide | Uncertain significance |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834354 | c.813G>C | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834357 | c.816T>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834361 | c.820T>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.21 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834369 | c.828C>G | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834375 | c.834G>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834378 | c.837T>C | synonymous_variant | 0.21 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834387 | c.846C>T | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834399 | p.His286Gln | missense_variant | 0.22 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834474 | c.933C>G | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834483 | c.942G>A | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834519 | c.978G>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834528 | c.987T>G | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834540 | c.999G>T | synonymous_variant | 0.14 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834543 | c.1002C>G | synonymous_variant | 0.13 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.13 | pyrazinamide | |
rpsA | 1834557 | p.Ala339Val | missense_variant | 0.14 | pyrazinamide | |
rpsA | 1834561 | c.1020C>G | synonymous_variant | 0.13 | pyrazinamide | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
bacA | 2062922 | p.Ile603Val | missense_variant | 1.0 | streptomycin | Not assoc w R |
kanamycin | Not assoc w R | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
bacA | 2063121 | c.1608A>T | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
kanamycin | Not assoc w R - Interim | |||||
capreomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Not assoc w R |
katG | 2155503 | c.609C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R |
PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
Rv1979c | 2222308 | p.Asp286Gly | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
kasA | 2518132 | c.18C>T | synonymous_variant | 1.0 | isoniazid | |
Rv2477c | 2783554 | c.489C>G | synonymous_variant | 0.12 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783563 | c.480A>G | synonymous_variant | 0.12 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783572 | c.471A>G | synonymous_variant | 0.12 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
ald | 3086728 | c.-92C>T | upstream_gene_variant | 1.0 | cycloserine | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
ald | 3087084 | c.266delA | frameshift_variant | 1.0 | cycloserine | |
Rv3236c | 3612143 | p.Arg325His | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
lpqB | 3624350 | c.561G>T | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R | |||||
lpqB | 3624486 | p.Asp142Gly | missense_variant | 1.0 | bedaquiline | Uncertain significance |
rifampicin | Not assoc w R | |||||
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | bedaquiline | Uncertain significance |
rifampicin | Not assoc w R | |||||
fbiB | 3642647 | c.1113C>G | synonymous_variant | 0.99 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
alr | 3840780 | p.Arg214Gln | missense_variant | 1.0 | cycloserine | |
rpoA | 3877743 | c.765T>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoA | 3877749 | c.759C>T | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoA | 3877752 | p.Asp252Glu | missense_variant | 0.15 | rifampicin | |
rpoA | 3877764 | p.Ala248Gly | missense_variant | 0.14 | rifampicin | |
rpoA | 3877770 | c.738A>C | synonymous_variant | 0.14 | rifampicin | |
rpoA | 3877773 | c.735G>C | synonymous_variant | 0.14 | rifampicin | |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoA | 3877785 | c.723C>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoA | 3877797 | c.711G>C | synonymous_variant | 0.15 | rifampicin | |
rpoA | 3877800 | c.708G>C | synonymous_variant | 0.15 | rifampicin | |
rpoA | 3877803 | c.705G>C | synonymous_variant | 0.15 | rifampicin | |
rpoA | 3877824 | c.684G>A | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoA | 3877833 | c.675C>G | synonymous_variant | 0.16 | rifampicin | |
rpoA | 3877836 | c.672A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>T | synonymous_variant | 0.16 | rifampicin | |
rpoA | 3877842 | c.666A>C | synonymous_variant | 0.16 | rifampicin | |
rpoA | 3877856 | c.652T>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoA | 3877866 | c.642G>C | synonymous_variant | 0.14 | rifampicin | |
rpoA | 3877875 | c.633T>G | synonymous_variant | 0.14 | rifampicin | |
rpoA | 3877881 | c.627G>C | synonymous_variant | 0.14 | rifampicin | |
rpoA | 3877884 | c.624G>C | synonymous_variant | 0.13 | rifampicin | |
rpoA | 3877893 | c.615C>G | synonymous_variant | 0.13 | rifampicin | |
rpoA | 3877898 | p.Pro204Ala | missense_variant | 0.14 | rifampicin | |
rpoA | 3877905 | c.603A>C | synonymous_variant | 0.13 | rifampicin | |
rpoA | 3877908 | c.600T>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.12 | pyrazinamide | |
clpC1 | 4038815 | c.1890G>C | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4038842 | c.1863G>C | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.14 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038896 | c.1809C>T | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4038899 | c.1806C>G | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4038905 | c.1800A>G | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4038911 | c.1794G>C | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4038917 | c.1788C>T | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4038923 | c.1780_1782delCTAinsTG | frameshift_variant&synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4038932 | c.1773G>C | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4038941 | c.1764G>C | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.12 | pyrazinamide | |
clpC1 | 4039004 | c.1701C>G | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4039037 | c.1668T>C | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4039046 | c.1659C>T | synonymous_variant | 0.13 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039079 | c.1626C>G | synonymous_variant | 0.12 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.12 | pyrazinamide | |
clpC1 | 4039133 | c.1572C>G | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4039409 | c.1296T>C | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4039412 | c.1293T>G | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4039415 | p.Glu430Asp | missense_variant | 0.13 | pyrazinamide | Uncertain significance |
clpC1 | 4039448 | c.1257A>G | synonymous_variant | 0.13 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039454 | c.1251A>C | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4039463 | c.1242C>G | synonymous_variant | 0.12 | pyrazinamide | |
clpC1 | 4039481 | c.1224T>C | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4039487 | c.1218G>C | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039517 | c.1188C>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039544 | c.1161C>T | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039553 | c.1152C>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039565 | c.1140G>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039570 | p.Met379Leu | missense_variant | 0.23 | pyrazinamide | Uncertain significance |
clpC1 | 4039571 | c.1134G>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039574 | p.Ala377Gly | missense_variant | 0.24 | pyrazinamide | |
clpC1 | 4039586 | c.1119G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039589 | c.1116G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039628 | c.1077C>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039634 | c.1069_1071delGAGinsAC | frameshift_variant&missense_variant | 0.23 | pyrazinamide | |
clpC1 | 4039649 | c.1056G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039652 | c.1053G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039661 | c.1044T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039682 | c.1023C>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039691 | c.1014G>C | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>T | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4039904 | c.801A>G | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039907 | c.798G>A | synonymous_variant | 0.14 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039913 | c.792C>T | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4039919 | c.786C>T | synonymous_variant | 0.14 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039925 | c.780C>T | synonymous_variant | 0.15 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4039934 | c.771G>C | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4039937 | c.768G>C | synonymous_variant | 0.13 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.12 | pyrazinamide | |
clpC1 | 4039958 | c.747G>C | synonymous_variant | 0.13 | pyrazinamide | |
glpK | 4138377 | p.Val460Ala | missense_variant | 1.0 | ethambutol | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
streptomycin | Not assoc w R | |||||
levofloxacin | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
glpK | 4139183 | c.572dupG | frameshift_variant | 0.8 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
embC | 4240671 | p.Thr270Ile | missense_variant | 1.0 | ethambutol | Not assoc w R |
embC | 4241843 | p.Leu661Ile | missense_variant | 1.0 | ethambutol | Not assoc w R |
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4244220 | c.988C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4244379 | p.Pro383Ser | missense_variant | 1.0 | ethambutol | Not assoc w R |
embB | 4246864 | c.351C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embB | 4247646 | p.Glu378Ala | missense_variant | 1.0 | ethambutol | Not assoc w R |
ubiA | 4269351 | c.483C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
ubiA | 4269387 | p.Glu149Asp | missense_variant | 1.0 | ethambutol | Not assoc w R |
ubiA | 4269522 | c.312C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
ubiA | 4269606 | c.228T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
ethA | 4326465 | p.Ile337Val | missense_variant | 1.0 | ethionamide | Uncertain significance |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | capreomycin | Not assoc w R |
amikacin | Not assoc w R | |||||
kanamycin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
gid | 4407588 | c.615A>G | synonymous_variant | 1.0 | streptomycin | Not assoc w R |
gid | 4408034 | p.Glu57Lys | missense_variant | 1.0 | streptomycin | Uncertain significance |