TB-Profiler result

Run: SRR1062919
Summary

Run ID: SRR1062919

Sample name:

Date: 02-04-2023 18:40:31

Number of reads: 738205

Percentage reads mapped: 27.33

Strain: lineage2.2.1

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 0.93
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 1.0
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 0.98
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1473246 n.1401A>G non_coding_transcript_exon_variant 0.21 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.79 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.65 kanamycin, capreomycin, aminoglycosides, amikacin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
embB 4247431 p.Met306Ile missense_variant 1.0 ethambutol
ethA 4327294 p.Tyr60* stop_gained 1.0 ethionamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6374 p.Glu379* stop_gained 0.12
gyrA 6673 c.-629A>C upstream_gene_variant 0.15
gyrA 6676 c.-626T>G upstream_gene_variant 0.14
gyrB 6680 p.Leu481Ile missense_variant 0.14
gyrA 6700 c.-602T>C upstream_gene_variant 0.15
gyrA 6703 c.-599G>C upstream_gene_variant 0.15
gyrA 6709 c.-593A>G upstream_gene_variant 0.15
gyrA 6760 c.-542G>C upstream_gene_variant 0.17
gyrA 6769 c.-533C>T upstream_gene_variant 0.17
gyrB 6770 p.Thr511Ala missense_variant 0.17
gyrA 6775 c.-527G>C upstream_gene_variant 0.17
gyrB 6787 p.Glu516Asp missense_variant 0.18
gyrB 6794 p.Ile519Leu missense_variant 0.18
gyrB 6797 p.Gly520Ser missense_variant 0.2
gyrB 6803 p.Leu522Val missense_variant 0.33
gyrA 6841 c.-461T>C upstream_gene_variant 0.4
gyrA 6844 c.-458T>C upstream_gene_variant 0.4
gyrA 6853 c.-449A>G upstream_gene_variant 0.27
gyrA 6856 c.-446T>C upstream_gene_variant 0.2
gyrA 6859 c.-443T>C upstream_gene_variant 0.2
gyrB 6860 p.Ser541Arg missense_variant 0.2
gyrA 6865 c.-437G>C upstream_gene_variant 0.2
gyrA 6869 c.-433T>C upstream_gene_variant 0.2
gyrA 6872 c.-430T>C upstream_gene_variant 0.2
gyrA 6878 c.-424T>C upstream_gene_variant 0.22
gyrA 6881 c.-421T>C upstream_gene_variant 0.22
gyrA 6889 c.-413G>C upstream_gene_variant 0.2
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7380 c.79_81delAGCinsTCG synonymous_variant 0.29
gyrA 7384 p.Tyr28Phe missense_variant 0.26
gyrA 7394 c.93T>C synonymous_variant 0.26
gyrA 7414 p.Gly38Ala missense_variant 0.3
gyrA 7418 c.117C>G synonymous_variant 0.32
gyrA 7421 c.120G>C synonymous_variant 0.26
gyrA 7430 p.Glu43Asp missense_variant 0.26
gyrA 7442 c.141G>A synonymous_variant 0.29
gyrA 7451 c.150C>G synonymous_variant 0.29
gyrA 7457 c.156T>C synonymous_variant 0.24
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7631 c.330G>C synonymous_variant 0.23
gyrA 7637 c.336C>G synonymous_variant 0.21
gyrA 7658 c.357A>C synonymous_variant 0.17
gyrA 7664 c.363T>C synonymous_variant 0.19
gyrA 7698 p.Arg133Trp missense_variant 0.13
gyrA 8264 c.963T>C synonymous_variant 0.35
gyrA 8267 c.966G>C synonymous_variant 0.38
gyrA 8270 c.969G>C synonymous_variant 0.47
gyrA 8283 p.Ile328Leu missense_variant 0.61
gyrA 8288 c.987T>C synonymous_variant 0.6
gyrA 8294 c.993T>G synonymous_variant 0.65
gyrA 8296 p.Tyr332Phe missense_variant 0.65
gyrA 8320 p.Ser340Asn missense_variant 0.58
gyrA 8324 c.1023T>C synonymous_variant 0.58
gyrA 8339 c.1038A>G synonymous_variant 0.54
gyrA 8342 c.1041G>C synonymous_variant 0.54
gyrA 8366 c.1065G>C synonymous_variant 0.43
gyrA 8754 p.Glu485Lys missense_variant 0.18
gyrA 8897 c.1596T>C synonymous_variant 0.29
gyrA 8903 c.1602T>C synonymous_variant 0.32
gyrA 8906 c.1605C>G synonymous_variant 0.33
gyrA 8907 p.Ser536Ala missense_variant 0.33
gyrA 8915 c.1614A>G synonymous_variant 0.54
gyrA 8939 c.1638T>C synonymous_variant 0.61
gyrA 8942 c.1641G>C synonymous_variant 0.65
gyrA 8945 c.1644G>C synonymous_variant 0.65
gyrA 8946 c.1645_1647delTTGinsCTT synonymous_variant 0.65
gyrA 8981 c.1680G>C synonymous_variant 0.54
gyrA 8982 p.Cys561Ser missense_variant 0.52
gyrA 8996 c.1695T>C synonymous_variant 0.55
gyrA 8998 p.Leu566Trp missense_variant 0.55
gyrA 9016 p.Thr572Asn missense_variant 0.25
gyrA 9018 p.Gln573Lys missense_variant 0.25
gyrA 9023 c.1722A>C synonymous_variant 0.2
gyrA 9024 c.1723C>A synonymous_variant 0.2
gyrA 9029 c.1728T>C synonymous_variant 0.21
gyrA 9032 c.1731T>C synonymous_variant 0.19
gyrA 9056 c.1755C>G synonymous_variant 0.13
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490833 c.51G>T synonymous_variant 0.18
fgd1 491742 c.960T>C synonymous_variant 1.0
ccsA 620268 c.378G>A synonymous_variant 0.18
rpoB 760418 c.612G>C synonymous_variant 0.14
rpoB 760430 p.Phe208Leu missense_variant 0.32
rpoB 760434 p.Val210Ile missense_variant 0.32
rpoB 760452 p.Val216Ile missense_variant 0.37
rpoB 760475 c.669A>G synonymous_variant 0.24
rpoB 760484 c.678A>G synonymous_variant 0.19
rpoB 760917 c.1111_1113delCGCinsAGG synonymous_variant 0.29
rpoB 760925 c.1119T>C synonymous_variant 0.29
rpoB 760928 c.1122G>C synonymous_variant 0.29
rpoB 760934 c.1128C>A synonymous_variant 0.38
rpoB 760946 c.1140A>G synonymous_variant 0.32
rpoB 760953 p.Ile383Val missense_variant 0.32
rpoB 760956 c.1150C>A synonymous_variant 0.33
rpoB 760964 c.1158C>G synonymous_variant 0.38
rpoB 760965 p.Met387Leu missense_variant 0.33
rpoB 760970 c.1164G>C synonymous_variant 0.33
rpoB 760973 c.1167G>C synonymous_variant 0.35
rpoB 760991 c.1185G>C synonymous_variant 0.43
rpoB 761003 c.1197C>G synonymous_variant 0.46
rpoB 761006 c.1200C>G synonymous_variant 0.48
rpoB 761015 c.1209G>C synonymous_variant 0.44
rpoB 761021 c.1215G>C synonymous_variant 0.42
rpoB 761027 c.1221A>G synonymous_variant 0.4
rpoB 761037 c.1231T>C synonymous_variant 0.33
rpoB 761051 c.1245G>C synonymous_variant 0.33
rpoB 761064 p.Ala420Ser missense_variant 0.32
rpoB 761070 p.Lys422Arg missense_variant 0.25
rpoB 761183 c.1377T>C synonymous_variant 0.14
rpoB 761189 c.1383T>G synonymous_variant 0.15
rpoB 761193 p.Gly463Ser missense_variant 0.16
rpoB 761217 p.Pro471Ser missense_variant 0.13
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.14
rpoB 761249 c.1443A>G synonymous_variant 0.17
rpoB 761255 c.1449T>C synonymous_variant 0.14
rpoB 761318 c.1512G>C synonymous_variant 0.25
rpoB 761327 c.1521A>G synonymous_variant 0.29
rpoB 761347 p.Val514Glu missense_variant 0.4
rpoB 761355 p.Val517Lys missense_variant 0.36
rpoB 761360 c.1554T>C synonymous_variant 0.33
rpoB 761362 p.Ser519Thr missense_variant 0.33
rpoB 761367 p.Glu521Gln missense_variant 0.33
rpoB 761374 p.Val523Asp missense_variant 0.33
rpoB 761396 c.1590G>A synonymous_variant 0.17
rpoB 761891 c.2085G>C synonymous_variant 0.39
rpoB 761906 c.2100C>G synonymous_variant 0.65
rpoB 761909 c.2103T>C synonymous_variant 0.65
rpoB 761912 c.2106T>C synonymous_variant 0.62
rpoB 761915 p.Asp703Glu missense_variant 0.65
rpoB 761917 p.Asp704Gly missense_variant 0.62
rpoB 761937 p.Lys711Arg missense_variant 0.57
rpoB 761951 c.2145G>C synonymous_variant 0.54
rpoB 761955 p.Ile717Phe missense_variant 0.57
rpoB 761972 c.2166C>T synonymous_variant 0.58
rpoB 761980 p.Tyr725Phe missense_variant 0.47
rpoB 761990 c.2184G>C synonymous_variant 0.36
rpoB 762053 c.2247T>C synonymous_variant 0.31
rpoB 762062 c.2256T>C synonymous_variant 0.36
rpoB 762065 c.2259T>C synonymous_variant 0.36
rpoB 762083 c.2277T>C synonymous_variant 0.46
rpoB 762084 p.Ala760Pro missense_variant 0.46
rpoB 762099 c.2293_2295delCGCinsAGG synonymous_variant 0.5
rpoB 762110 c.2304G>C synonymous_variant 0.45
rpoB 762114 p.Ile770Val missense_variant 0.53
rpoB 762122 p.Asp772Glu missense_variant 0.5
rpoB 762131 c.2325C>G synonymous_variant 0.47
rpoB 762134 c.2328C>G synonymous_variant 0.47
rpoB 762143 c.2337T>C synonymous_variant 0.47
rpoB 762149 c.2343G>T synonymous_variant 0.56
rpoB 762158 c.2352G>C synonymous_variant 0.65
rpoB 762161 c.2355C>G synonymous_variant 0.61
rpoB 762176 c.2370T>G synonymous_variant 0.61
rpoB 762178 p.Arg791Gln missense_variant 0.61
rpoB 762185 c.2379G>C synonymous_variant 0.66
rpoB 762218 c.2412T>C synonymous_variant 0.77
rpoB 762233 c.2427G>C synonymous_variant 0.76
rpoB 762254 c.2448T>C synonymous_variant 0.7
rpoB 762257 c.2451C>G synonymous_variant 0.67
rpoB 762266 c.2460T>C synonymous_variant 0.66
rpoB 762278 c.2472C>T synonymous_variant 0.58
rpoB 762293 c.2487T>C synonymous_variant 0.45
rpoB 762296 c.2490G>C synonymous_variant 0.45
rpoB 762299 c.2493G>C synonymous_variant 0.45
rpoB 762317 c.2511A>G synonymous_variant 0.33
rpoB 762318 p.Ser838Thr missense_variant 0.33
rpoB 762329 c.2523G>C synonymous_variant 0.17
rpoB 762362 p.Glu852Asp missense_variant 0.21
rpoB 762364 p.Asp853Ala missense_variant 0.19
rpoB 762369 c.2563T>C synonymous_variant 0.25
rpoC 762374 c.-996G>C upstream_gene_variant 0.23
rpoC 762380 c.-990T>C upstream_gene_variant 0.38
rpoC 762395 c.-975G>C upstream_gene_variant 0.45
rpoC 762398 c.-972T>G upstream_gene_variant 0.45
rpoC 762404 c.-966T>C upstream_gene_variant 0.5
rpoC 762410 c.-960T>C upstream_gene_variant 0.53
rpoC 762416 c.-954A>G upstream_gene_variant 0.56
rpoB 762426 p.Ser874Gln missense_variant 0.49
rpoC 762434 c.-936T>C upstream_gene_variant 0.56
rpoC 762443 c.-927G>C upstream_gene_variant 0.6
rpoC 762470 c.-900G>C upstream_gene_variant 0.57
rpoC 762491 c.-879T>G upstream_gene_variant 0.61
rpoC 762503 c.-867G>C upstream_gene_variant 0.59
rpoC 762509 c.-861T>G upstream_gene_variant 0.56
rpoB 762510 p.Ala902Pro missense_variant 0.56
rpoC 762527 c.-843G>C upstream_gene_variant 0.52
rpoC 762533 c.-837T>C upstream_gene_variant 0.42
rpoB 762534 p.Ile910Val missense_variant 0.44
rpoC 762537 c.-833T>C upstream_gene_variant 0.46
rpoB 762543 p.Thr913Pro missense_variant 0.45
rpoC 762581 c.-789T>C upstream_gene_variant 0.22
rpoC 762582 c.-788T>C upstream_gene_variant 0.22
rpoB 762786 p.Val994Arg missense_variant 0.22
rpoB 762789 p.Leu995Met missense_variant 0.22
rpoB 762799 p.Ala998Val missense_variant 0.2
rpoB 762803 p.Asp999Glu missense_variant 0.21
rpoC 762812 c.-558C>G upstream_gene_variant 0.2
rpoB 762813 p.Met1003Gln missense_variant 0.21
rpoC 762818 c.-552C>G upstream_gene_variant 0.28
rpoC 762830 c.-540C>T upstream_gene_variant 0.36
rpoC 762831 c.-539_-538delAGinsTC upstream_gene_variant 0.36
rpoB 762858 p.Thr1018Ala missense_variant 0.57
rpoC 762863 c.-507T>C upstream_gene_variant 0.63
rpoB 762878 p.Ile1024Met missense_variant 0.68
rpoB 762879 p.Met1025Leu missense_variant 0.68
rpoB 762888 p.His1028Asn missense_variant 0.82
rpoC 762918 c.-452_-450delCGCinsAGG upstream_gene_variant 0.84
rpoC 762929 c.-441G>C upstream_gene_variant 0.85
rpoC 762995 c.-375G>C upstream_gene_variant 0.72
rpoC 763028 c.-342T>C upstream_gene_variant 0.69
rpoC 763031 c.-339T>G upstream_gene_variant 1.0
rpoC 763040 c.-330C>G upstream_gene_variant 0.62
rpoC 763052 c.-318G>C upstream_gene_variant 0.55
rpoC 763065 c.-305_-304delTCinsAG upstream_gene_variant 0.5
rpoC 763070 c.-300T>C upstream_gene_variant 0.57
rpoB 763075 p.Thr1090Ile missense_variant 0.57
rpoC 763085 c.-285C>G upstream_gene_variant 0.71
rpoC 763094 c.-276G>C upstream_gene_variant 0.71
rpoC 763103 c.-267G>C upstream_gene_variant 0.71
rpoB 763104 p.Ile1100Val missense_variant 0.7
rpoC 763109 c.-261C>G upstream_gene_variant 0.68
rpoC 763115 c.-255T>C upstream_gene_variant 0.69
rpoC 763127 c.-243G>C upstream_gene_variant 0.65
rpoC 763166 c.-204A>G upstream_gene_variant 0.63
rpoC 763169 c.-201A>G upstream_gene_variant 0.59
rpoB 763176 p.Ser1124Ala missense_variant 0.62
rpoC 763187 c.-183C>G upstream_gene_variant 0.33
rpoC 763193 c.-177C>G upstream_gene_variant 0.33
rpoC 763480 c.111C>A synonymous_variant 0.26
rpoC 763483 c.114G>C synonymous_variant 0.25
rpoC 763486 c.117T>G synonymous_variant 0.3
rpoC 763504 c.135C>G synonymous_variant 0.5
rpoC 763507 c.138G>C synonymous_variant 0.55
rpoC 763528 c.159G>C synonymous_variant 0.64
rpoC 763531 c.162G>C synonymous_variant 0.66
rpoC 763534 c.165T>C synonymous_variant 0.68
rpoC 763537 c.168C>G synonymous_variant 0.65
rpoC 763546 c.177A>G synonymous_variant 0.67
rpoC 763550 p.Tyr61Ala missense_variant 0.67
rpoC 763594 c.225C>T synonymous_variant 0.7
rpoC 763621 c.252C>T synonymous_variant 0.68
rpoC 763630 c.261G>A synonymous_variant 0.63
rpoC 763636 c.267T>C synonymous_variant 0.6
rpoC 763648 c.279C>T synonymous_variant 0.62
rpoC 763660 c.291T>G synonymous_variant 0.57
rpoC 763666 c.297G>T synonymous_variant 0.54
rpoC 763669 c.300C>G synonymous_variant 0.56
rpoC 763702 c.333C>G synonymous_variant 0.35
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 0.35
rpoC 763711 c.342G>C synonymous_variant 0.37
rpoC 763714 c.345G>T synonymous_variant 0.35
rpoC 763717 c.348T>C synonymous_variant 0.39
rpoC 763723 c.354G>C synonymous_variant 0.43
rpoC 763732 c.363C>G synonymous_variant 0.46
rpoC 763735 c.366G>C synonymous_variant 0.46
rpoC 763741 c.372C>T synonymous_variant 0.45
rpoC 763744 c.375G>C synonymous_variant 0.46
rpoC 763765 c.396T>C synonymous_variant 0.41
rpoC 763772 p.Val135Leu missense_variant 0.33
rpoC 763786 c.417C>G synonymous_variant 0.13
rpoC 763940 p.Ala191Ser missense_variant 0.17
rpoC 763945 c.576T>C synonymous_variant 0.16
rpoC 763948 c.579G>C synonymous_variant 0.16
rpoC 763951 c.582G>C synonymous_variant 0.14
rpoC 763960 c.591T>G synonymous_variant 0.29
rpoC 763982 p.Met205Gln missense_variant 0.22
rpoC 763987 c.618C>A synonymous_variant 0.22
rpoC 764246 p.Leu293Ile missense_variant 0.38
rpoC 764266 c.897T>G synonymous_variant 0.35
rpoC 764269 c.900G>C synonymous_variant 0.35
rpoC 764284 c.915G>C synonymous_variant 0.36
rpoC 764297 p.Met310Leu missense_variant 0.46
rpoC 764311 c.942C>G synonymous_variant 0.56
rpoC 764315 p.Ala316Cys missense_variant 0.54
rpoC 764339 p.Leu324Ile missense_variant 0.65
rpoC 764359 c.990C>G synonymous_variant 0.59
rpoC 764380 c.1011G>C synonymous_variant 0.68
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.65
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.67
rpoC 764428 c.1059G>C synonymous_variant 0.54
rpoC 764429 c.1060C>T synonymous_variant 0.52
rpoC 764434 c.1065A>G synonymous_variant 0.5
rpoC 764435 c.1066A>C synonymous_variant 0.46
rpoC 764443 p.Ile358Met missense_variant 0.48
rpoC 764446 c.1077T>C synonymous_variant 0.48
rpoC 764449 c.1080G>C synonymous_variant 0.5
rpoC 764452 c.1083T>C synonymous_variant 0.45
rpoC 764458 c.1089G>C synonymous_variant 0.44
rpoC 764461 c.1092A>G synonymous_variant 0.5
rpoC 764497 c.1128A>G synonymous_variant 0.45
rpoC 764498 p.Ser377Ala missense_variant 0.45
rpoC 764503 c.1134G>C synonymous_variant 0.5
rpoC 764521 c.1152T>C synonymous_variant 0.49
rpoC 764524 c.1155C>T synonymous_variant 0.51
rpoC 764536 c.1167G>C synonymous_variant 0.58
rpoC 764566 c.1197C>G synonymous_variant 0.64
rpoC 764575 c.1206T>G synonymous_variant 0.65
rpoC 764578 c.1209C>G synonymous_variant 0.64
rpoC 764611 c.1242G>T synonymous_variant 0.63
rpoC 764644 c.1275G>C synonymous_variant 0.7
rpoC 764650 c.1281G>C synonymous_variant 0.75
rpoC 764656 c.1287C>G synonymous_variant 0.78
rpoC 764662 c.1293G>C synonymous_variant 0.78
rpoC 764677 c.1308C>G synonymous_variant 0.76
rpoC 764690 p.Cys441Ala missense_variant 0.79
rpoC 764695 c.1326T>C synonymous_variant 0.8
rpoC 764701 c.1332C>G synonymous_variant 0.82
rpoC 764746 c.1377G>A synonymous_variant 0.7
rpoC 764752 c.1383G>T synonymous_variant 0.66
rpoC 764758 c.1389C>G synonymous_variant 0.58
rpoC 764759 p.Asn464Gly missense_variant 0.58
rpoC 764764 c.1395T>C synonymous_variant 0.6
rpoC 764767 c.1398G>C synonymous_variant 0.61
rpoC 764780 c.1411_1412delAGinsTC synonymous_variant 0.62
rpoC 764791 c.1422C>G synonymous_variant 0.69
rpoC 764812 c.1443C>G synonymous_variant 0.68
rpoC 764815 c.1446A>G synonymous_variant 0.65
rpoC 764824 c.1455T>C synonymous_variant 0.65
rpoC 764830 c.1461C>G synonymous_variant 0.59
rpoC 764833 c.1464A>G synonymous_variant 0.57
rpoC 764844 p.Ala492Gly missense_variant 0.56
rpoC 764847 p.Glu493Ala missense_variant 0.57
rpoC 764858 c.1489T>C synonymous_variant 0.67
rpoC 764872 c.1503A>T synonymous_variant 0.67
rpoC 764893 c.1524T>C synonymous_variant 0.57
rpoC 764902 c.1533C>G synonymous_variant 0.55
rpoC 764911 c.1542A>G synonymous_variant 0.53
rpoC 764912 p.Met515Gln missense_variant 0.53
rpoC 764920 c.1551G>C synonymous_variant 0.6
rpoC 764923 c.1554A>G synonymous_variant 0.56
rpoC 764935 c.1566T>C synonymous_variant 0.58
rpoC 764939 c.1570C>T synonymous_variant 0.57
rpoC 764958 p.Glu530Ala missense_variant 0.41
rpoC 764968 c.1599T>C synonymous_variant 0.33
rpoC 765454 c.2085C>G synonymous_variant 0.33
rpoC 765458 p.Ile697Val missense_variant 0.33
rpoC 765466 c.2097C>T synonymous_variant 0.28
rpoC 765469 c.2100G>C synonymous_variant 0.29
rpoC 765477 p.Arg703His missense_variant 0.29
rpoC 765489 p.Ile707Ser missense_variant 0.29
rpoC 765491 p.Val708Leu missense_variant 0.31
rpoC 765499 c.2130C>G synonymous_variant 0.31
rpoC 765506 p.Val713Leu missense_variant 0.28
rpoC 765523 p.Asp718Glu missense_variant 0.33
rpoC 765892 c.2523T>C synonymous_variant 0.29
rpoC 765902 p.Thr845Ser missense_variant 0.41
rpoC 765932 p.Gly855Ser missense_variant 0.48
rpoC 765937 c.2568T>G synonymous_variant 0.46
rpoC 765967 c.2598C>G synonymous_variant 0.52
rpoC 765976 p.Asp869Glu missense_variant 0.52
rpoC 765979 c.2610C>G synonymous_variant 0.48
rpoC 765982 c.2613C>T synonymous_variant 0.44
rpoC 765994 c.2625A>T synonymous_variant 0.35
rpoC 765997 c.2628T>G synonymous_variant 0.28
rpoC 766543 c.3174C>A synonymous_variant 0.15
rpoC 766843 c.3474T>C synonymous_variant 0.21
rpoC 766846 c.3477C>G synonymous_variant 0.21
rpoC 766868 p.Ile1167Val missense_variant 0.25
rpoC 767002 c.3633G>C synonymous_variant 0.5
rpoC 767023 p.Asp1218Glu missense_variant 0.54
rpoC 767035 c.3666G>C synonymous_variant 0.44
rpoC 767041 c.3672G>C synonymous_variant 0.38
rpoC 767044 c.3675G>C synonymous_variant 0.46
rpoC 767059 c.3690T>C synonymous_variant 0.37
rpoC 767060 p.Arg1231Lys missense_variant 0.37
rpoC 767068 c.3699G>C synonymous_variant 0.47
rpoC 767077 c.3708G>C synonymous_variant 0.45
rpoC 767087 p.Cys1240Gly missense_variant 0.5
rpoC 767098 c.3729T>C synonymous_variant 0.35
rpoC 767101 p.Lys1244Asn missense_variant 0.14
rpoC 767104 c.3735C>G synonymous_variant 0.27
rpoC 767105 p.Asn1246Val missense_variant 0.21
rpoC 767110 c.3741T>C synonymous_variant 0.21
rpoC 767119 c.3750A>G synonymous_variant 0.27
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775811 p.Phe890Leu missense_variant 0.2
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 777597 p.Arg295Pro missense_variant 1.0
mmpR5 778169 c.-821G>A upstream_gene_variant 0.13
mmpS5 778537 p.Lys123Asn missense_variant 0.15
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781658 c.99A>G synonymous_variant 0.15
rpsL 781700 c.141G>C synonymous_variant 0.19
rpsL 781706 c.147T>G synonymous_variant 0.19
rpsL 781754 c.195G>C synonymous_variant 0.19
rpsL 781772 c.213C>A synonymous_variant 0.2
rpsL 781793 c.234G>C synonymous_variant 0.21
rpsL 781796 p.Met79Ile missense_variant 0.22
rpsL 781805 c.246G>C synonymous_variant 0.25
rpsL 781817 c.258G>T synonymous_variant 0.33
rpsL 781832 c.273T>C synonymous_variant 0.38
rpsL 781835 c.276T>C synonymous_variant 0.37
rpsL 781838 c.279G>T synonymous_variant 0.35
rpsL 781841 c.282C>T synonymous_variant 0.39
rpsL 781865 c.306G>C synonymous_variant 0.41
rpsL 781868 c.309T>C synonymous_variant 0.41
rpsL 781871 c.312G>C synonymous_variant 0.41
rpsL 781877 c.318T>C synonymous_variant 0.41
rpsL 781880 c.321C>G synonymous_variant 0.41
rpsL 781892 c.333A>G synonymous_variant 0.38
rpsL 781898 c.339A>T synonymous_variant 0.37
rpsL 781907 c.348T>G synonymous_variant 0.29
rpsL 781916 c.357T>G synonymous_variant 0.26
rpsL 781929 p.Gly124Ser missense_variant 0.22
rplC 800612 c.-197A>G upstream_gene_variant 0.3
rplC 800615 c.-194G>C upstream_gene_variant 0.32
rplC 800618 c.-191T>C upstream_gene_variant 0.36
rplC 800630 c.-179G>T upstream_gene_variant 0.46
rplC 800633 c.-176T>C upstream_gene_variant 0.5
rplC 800648 c.-161A>G upstream_gene_variant 0.58
rplC 800672 c.-137G>C upstream_gene_variant 0.72
rplC 800693 c.-116A>G upstream_gene_variant 0.69
rplC 800703 c.-106T>C upstream_gene_variant 0.68
rplC 800715 c.-94A>C upstream_gene_variant 0.68
rplC 800720 c.-89T>C upstream_gene_variant 0.67
rplC 800723 c.-86C>G upstream_gene_variant 0.62
rplC 800729 c.-80G>C upstream_gene_variant 0.62
rplC 800735 c.-74C>G upstream_gene_variant 0.55
rplC 800747 c.-62C>G upstream_gene_variant 0.44
rplC 800886 c.78G>A synonymous_variant 0.2
rplC 801040 p.Arg78Ser missense_variant 0.12
rplC 801103 p.Gln99Lys missense_variant 0.22
rplC 801309 c.501C>T synonymous_variant 0.14
fbiC 1303432 p.Asp168Asn missense_variant 0.14
fbiC 1304635 p.Gln569* stop_gained 0.13
Rv1258c 1406819 p.Met174Ile missense_variant 0.15
embR 1417331 p.Thr6Ile missense_variant 0.17
atpE 1461281 c.237C>T synonymous_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.54
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.57
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.62
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.64
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.25
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.25
rrs 1471972 n.127T>C non_coding_transcript_exon_variant 0.23
rrs 1471982 n.137A>T non_coding_transcript_exon_variant 0.19
rrs 1471984 n.140_141delTC non_coding_transcript_exon_variant 0.21
rrs 1471997 n.152T>C non_coding_transcript_exon_variant 0.23
rrs 1472005 n.160T>C non_coding_transcript_exon_variant 0.23
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.43
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.72
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.75
rrs 1472122 n.277G>A non_coding_transcript_exon_variant 0.81
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.86
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.85
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.83
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.63
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.56
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.21
rrs 1472326 n.481T>A non_coding_transcript_exon_variant 0.58
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.58
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.72
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.87
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.75
rrs 1472426 n.581T>C non_coding_transcript_exon_variant 0.67
rrs 1472494 n.649A>T non_coding_transcript_exon_variant 0.5
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.45
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.62
rrs 1472506 n.661A>T non_coding_transcript_exon_variant 0.69
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.87
rrs 1472572 n.727T>A non_coding_transcript_exon_variant 0.83
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.82
rrs 1472583 n.738T>A non_coding_transcript_exon_variant 0.82
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.82
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.73
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.65
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.65
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.62
rrs 1472674 n.829T>A non_coding_transcript_exon_variant 0.6
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.6
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.57
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.57
rrs 1472686 n.841G>T non_coding_transcript_exon_variant 0.57
rrs 1472687 n.842A>C non_coding_transcript_exon_variant 0.59
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.62
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.67
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.67
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.59
rrs 1472791 n.946G>T non_coding_transcript_exon_variant 0.6
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.31
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.31
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.31
rrs 1472837 n.992C>T non_coding_transcript_exon_variant 0.25
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.26
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.79
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.8
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.79
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.81
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.81
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.7
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.7
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.71
rrs 1473065 n.1220C>A non_coding_transcript_exon_variant 0.73
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.73
rrs 1473097 n.1252G>A non_coding_transcript_exon_variant 0.69
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.66
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.67
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.67
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.64
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.64
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.65
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.65
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.58
rrs 1473158 n.1313T>C non_coding_transcript_exon_variant 0.56
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.59
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.8
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.74
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.73
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.68
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.73
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.71
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.68
rrl 1473428 n.-229delG upstream_gene_variant 0.14
rrl 1473471 n.-187C>A upstream_gene_variant 0.21
rrl 1473771 n.114T>A non_coding_transcript_exon_variant 0.4
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.45
rrl 1473792 n.135C>G non_coding_transcript_exon_variant 0.45
rrl 1473797 n.140G>C non_coding_transcript_exon_variant 0.5
rrl 1473803 n.146G>C non_coding_transcript_exon_variant 0.5
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.5
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.5
rrl 1473815 n.158T>C non_coding_transcript_exon_variant 0.55
rrl 1473821 n.164T>C non_coding_transcript_exon_variant 0.7
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 0.73
rrl 1473833 n.176_177insT non_coding_transcript_exon_variant 0.76
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.86
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 0.88
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.88
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.88
rrl 1473883 n.226A>G non_coding_transcript_exon_variant 0.82
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.78
rrl 1473888 n.231T>C non_coding_transcript_exon_variant 0.78
rrl 1473890 n.233T>C non_coding_transcript_exon_variant 0.78
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.78
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 0.78
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.75
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.69
rrl 1474097 n.440C>A non_coding_transcript_exon_variant 0.18
rrl 1474127 n.470G>A non_coding_transcript_exon_variant 0.13
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.24
rrl 1474139 n.482C>T non_coding_transcript_exon_variant 0.3
rrl 1474153 n.496C>G non_coding_transcript_exon_variant 0.27
rrl 1474166 n.509G>C non_coding_transcript_exon_variant 0.32
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.43
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.43
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.46
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.44
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.46
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.5
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.37
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.23
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.21
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.14
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.17
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.3
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.45
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.42
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.42
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.42
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.42
rrl 1474381 n.724T>A non_coding_transcript_exon_variant 0.42
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.46
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.35
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.15
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.43
rrl 1474488 n.831G>A non_coding_transcript_exon_variant 0.58
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.68
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.68
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.71
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.71
rrl 1474516 n.859C>T non_coding_transcript_exon_variant 0.73
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.72
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.71
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.69
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.69
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.69
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.74
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.13
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.12
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.19
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.29
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.33
rrl 1474742 n.1085A>C non_coding_transcript_exon_variant 0.28
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.38
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.35
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.35
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.63
rrl 1474784 n.1127C>T non_coding_transcript_exon_variant 0.67
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.76
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.78
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.77
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.75
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 0.75
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 0.79
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.65
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.65
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.65
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.65
rrl 1474944 n.1287G>A non_coding_transcript_exon_variant 0.38
rrl 1475060 n.1404delC non_coding_transcript_exon_variant 0.45
rrl 1475065 n.1409_1410delCA non_coding_transcript_exon_variant 0.45
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 0.38
rrl 1475080 n.1423G>C non_coding_transcript_exon_variant 0.38
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 0.38
rrl 1475084 n.1427G>A non_coding_transcript_exon_variant 0.35
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.48
rrl 1475113 n.1456C>T non_coding_transcript_exon_variant 0.67
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.67
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.67
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.5
rrl 1475440 n.1783T>G non_coding_transcript_exon_variant 0.5
rrl 1475441 n.1784T>C non_coding_transcript_exon_variant 0.44
rrl 1475442 n.1785C>A non_coding_transcript_exon_variant 0.44
rrl 1475443 n.1786_1787insA non_coding_transcript_exon_variant 0.44
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.45
rrl 1475458 n.1801C>T non_coding_transcript_exon_variant 0.45
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.45
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 0.44
rrl 1475481 n.1825delA non_coding_transcript_exon_variant 0.44
rrl 1475484 n.1827A>T non_coding_transcript_exon_variant 0.41
rrl 1475485 n.1828C>A non_coding_transcript_exon_variant 0.41
rrl 1475486 n.1829A>G non_coding_transcript_exon_variant 0.41
rrl 1475499 n.1842C>T non_coding_transcript_exon_variant 0.68
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.67
rrl 1475536 n.1879C>T non_coding_transcript_exon_variant 0.68
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.68
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.68
rrl 1475544 n.1887A>C non_coding_transcript_exon_variant 0.71
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.71
rrl 1475573 n.1916G>A non_coding_transcript_exon_variant 0.71
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.36
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.29
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.5
rrl 1475655 n.1998T>C non_coding_transcript_exon_variant 0.53
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.61
rrl 1475688 n.2031G>A non_coding_transcript_exon_variant 0.59
rrl 1475692 n.2035G>T non_coding_transcript_exon_variant 0.62
rrl 1475707 n.2050T>C non_coding_transcript_exon_variant 0.59
rrl 1475713 n.2056C>T non_coding_transcript_exon_variant 0.65
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.62
rrl 1475761 n.2104C>T non_coding_transcript_exon_variant 0.67
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.67
rrl 1475764 n.2107A>G non_coding_transcript_exon_variant 0.67
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.67
rrl 1475767 n.2110G>A non_coding_transcript_exon_variant 0.71
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.74
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.75
rrl 1475883 n.2226A>G non_coding_transcript_exon_variant 0.88
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.84
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.72
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.62
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.63
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.62
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.52
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.47
rrl 1476000 n.2343G>A non_coding_transcript_exon_variant 0.43
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.43
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.57
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.75
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.75
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.71
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.64
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.67
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.67
rrl 1476213 n.2556G>T non_coding_transcript_exon_variant 0.68
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.67
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.64
rrl 1476229 n.2572C>A non_coding_transcript_exon_variant 0.57
rrl 1476250 n.2593C>T non_coding_transcript_exon_variant 0.33
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.25
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.25
rrl 1476255 n.2598A>G non_coding_transcript_exon_variant 0.25
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.25
rrl 1476257 n.2600G>A non_coding_transcript_exon_variant 0.25
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.25
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.6
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.62
rrl 1476297 n.2640C>A non_coding_transcript_exon_variant 0.69
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.69
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.69
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.8
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.8
rrl 1476423 n.2766T>C non_coding_transcript_exon_variant 0.74
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.8
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.75
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.65
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.62
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.62
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 0.65
rrl 1476529 n.2872A>T non_coding_transcript_exon_variant 0.65
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.76
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.76
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.76
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.86
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.84
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.76
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.74
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.7
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.64
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.67
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.67
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.62
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.65
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.62
rpsA 1833646 c.105T>C synonymous_variant 0.48
rpsA 1833666 p.Thr42Ser missense_variant 0.57
rpsA 1833676 c.135A>G synonymous_variant 0.59
rpsA 1833677 p.Val46Ile missense_variant 0.59
rpsA 1833685 c.144G>C synonymous_variant 0.62
rpsA 1833697 c.156C>G synonymous_variant 0.67
rpsA 1833709 c.168C>T synonymous_variant 0.67
rpsA 1833727 c.186G>C synonymous_variant 0.59
rpsA 1833734 p.Ala65Ser missense_variant 0.61
rpsA 1833829 c.288A>G synonymous_variant 0.19
rpsA 1833832 c.291G>A synonymous_variant 0.19
rpsA 1833838 c.297G>T synonymous_variant 0.2
rpsA 1833847 c.306C>G synonymous_variant 0.21
rpsA 1833856 c.315A>G synonymous_variant 0.21
rpsA 1833862 c.321G>T synonymous_variant 0.2
rpsA 1833874 c.333T>G synonymous_variant 0.27
rpsA 1833886 c.345C>G synonymous_variant 0.33
rpsA 1833928 c.387G>C synonymous_variant 0.3
rpsA 1833949 c.408T>C synonymous_variant 0.55
rpsA 1833970 c.429G>T synonymous_variant 0.52
rpsA 1833979 c.438T>C synonymous_variant 0.54
rpsA 1833991 c.450C>G synonymous_variant 0.59
rpsA 1834000 c.459G>C synonymous_variant 0.62
rpsA 1834012 c.471G>T synonymous_variant 0.74
rpsA 1834015 c.474G>C synonymous_variant 0.73
rpsA 1834030 c.489C>G synonymous_variant 0.64
rpsA 1834034 p.Ile165Val missense_variant 0.61
rpsA 1834040 p.Lys167Arg missense_variant 0.67
rpsA 1834043 p.Glu168Gln missense_variant 0.62
rpsA 1834046 p.Ile169Leu missense_variant 0.67
rpsA 1834051 p.Glu170Asp missense_variant 0.71
rpsA 1834069 c.528G>C synonymous_variant 0.7
rpsA 1834105 c.564C>G synonymous_variant 0.36
rpsA 1834106 p.Ala189Gln missense_variant 0.36
rpsA 1834135 c.594G>C synonymous_variant 0.31
rpsA 1834150 c.609G>C synonymous_variant 0.17
rpsA 1834177 c.636A>C synonymous_variant 1.0
rpsA 1834187 p.Val216Leu missense_variant 0.18
rpsA 1834195 c.654G>C synonymous_variant 0.21
rpsA 1834213 c.672G>C synonymous_variant 0.31
rpsA 1834231 c.690T>G synonymous_variant 0.42
rpsA 1834240 c.699T>C synonymous_variant 0.46
rpsA 1834249 c.708T>C synonymous_variant 0.52
rpsA 1834261 c.720A>G synonymous_variant 0.62
rpsA 1834264 c.723G>C synonymous_variant 0.61
rpsA 1834298 p.Gln253Glu missense_variant 0.6
rpsA 1834303 c.762T>C synonymous_variant 0.57
rpsA 1834306 c.765T>C synonymous_variant 0.57
rpsA 1834307 p.Asp256Gln missense_variant 0.57
rpsA 1834312 c.771G>A synonymous_variant 0.6
rpsA 1834330 c.789C>T synonymous_variant 0.61
rpsA 1834333 c.792C>T synonymous_variant 0.63
rpsA 1834348 c.807T>C synonymous_variant 0.73
rpsA 1834357 c.816T>C synonymous_variant 0.67
rpsA 1834361 c.820T>C synonymous_variant 0.63
rpsA 1834366 c.825A>G synonymous_variant 0.63
rpsA 1834375 c.834G>C synonymous_variant 0.66
rpsA 1834378 c.837T>C synonymous_variant 0.66
rpsA 1834387 c.846C>T synonymous_variant 0.62
rpsA 1834390 c.849G>C synonymous_variant 0.64
rpsA 1834411 c.870T>C synonymous_variant 0.67
rpsA 1834423 c.882G>C synonymous_variant 0.66
rpsA 1834438 c.897C>T synonymous_variant 0.56
rpsA 1834439 p.Lys300Arg missense_variant 0.55
rpsA 1834451 c.910T>C synonymous_variant 0.6
rpsA 1834456 c.915T>G synonymous_variant 0.58
rpsA 1834468 c.927A>G synonymous_variant 0.56
rpsA 1834477 c.936C>G synonymous_variant 0.4
rpsA 1834480 c.939C>G synonymous_variant 0.38
rpsA 1834481 p.Glu314Tyr missense_variant 0.38
rpsA 1834486 p.Glu315Asp missense_variant 0.38
rpsA 1834489 c.948T>C synonymous_variant 0.38
rpsA 1834498 c.957C>T synonymous_variant 0.36
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154239 p.Thr625Ala missense_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2156449 c.-338G>A upstream_gene_variant 0.17
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2290051 c.-810C>A upstream_gene_variant 0.22
kasA 2517917 c.-198G>A upstream_gene_variant 0.25
kasA 2517921 c.-194A>G upstream_gene_variant 0.25
kasA 2517934 c.-181A>T upstream_gene_variant 0.29
kasA 2519300 p.Tyr396Asn missense_variant 0.18
eis 2714132 p.Glu401* stop_gained 0.13
eis 2715080 p.Val85Ile missense_variant 0.25
folC 2747395 p.His68Gln missense_variant 0.2
ribD 2987293 p.Thr152Met missense_variant 0.25
Rv2752c 3064851 p.Met447Ile missense_variant 0.14
thyX 3067887 p.Pro20Leu missense_variant 0.13
ald 3086694 c.-126C>A upstream_gene_variant 0.14
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087238 c.424_426delGCC conservative_inframe_deletion 0.18
fbiD 3339564 c.447G>A synonymous_variant 1.0
fbiD 3339592 p.His159Asp missense_variant 0.29
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474319 p.Gly105Cys missense_variant 0.17
fprA 3475053 c.1047C>T synonymous_variant 0.18
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
fbiB 3641684 p.Ser50Arg missense_variant 0.15
fbiB 3642700 p.Ala389Val missense_variant 0.15
fbiB 3642794 c.1260G>A synonymous_variant 0.15
rpoA 3877613 p.Ile299Val missense_variant 0.17
rpoA 3877617 c.891G>C synonymous_variant 0.17
rpoA 3877623 c.885C>T synonymous_variant 0.21
rpoA 3877629 c.879C>G synonymous_variant 0.33
rpoA 3877656 c.852T>G synonymous_variant 0.45
rpoA 3877667 p.Ser281Ala missense_variant 0.43
rpoA 3877668 c.840A>G synonymous_variant 0.45
rpoA 3877677 p.Ala277Gly missense_variant 0.47
rpoA 3877680 c.828G>C synonymous_variant 0.5
rpoA 3877686 c.822A>G synonymous_variant 0.5
rpoA 3877692 c.816G>C synonymous_variant 0.5
rpoA 3877701 p.Val269Ile missense_variant 0.44
rpoA 3877704 c.804G>C synonymous_variant 0.42
rpoA 3877719 c.789C>T synonymous_variant 0.45
rpoA 3877731 c.777G>C synonymous_variant 0.28
rpoA 3877734 c.774G>C synonymous_variant 0.21
rpoA 3877737 c.771G>C synonymous_variant 0.2
rpoA 3877743 c.765T>C synonymous_variant 0.17
rpoA 3877748 p.Leu254Met missense_variant 0.18
rpoA 3877749 p.Asp253Glu missense_variant 0.18
rpoA 3877752 p.Asp252Glu missense_variant 0.17
rpoA 3877765 p.Ala248Ser missense_variant 0.19
rpoA 3877770 p.Ser246Ala missense_variant 0.19
rpoA 3877776 c.732T>C synonymous_variant 0.19
rpoA 3877782 c.726T>C synonymous_variant 0.2
rpoA 3877803 c.705G>T synonymous_variant 0.19
rpoA 3877806 c.702C>T synonymous_variant 0.2
rpoA 3878053 p.Asn152Ser missense_variant 1.0
rpoA 3878079 c.429C>T synonymous_variant 0.14
rpoA 3878082 c.426T>C synonymous_variant 0.12
rpoA 3878163 c.345C>T synonymous_variant 0.18
rpoA 3878205 c.303T>A synonymous_variant 0.13
rpoA 3878217 c.291A>G synonymous_variant 0.14
rpoA 3878227 p.Thr94Val missense_variant 0.14
ddn 3986861 c.18G>A synonymous_variant 0.14
clpC1 4038554 p.Ile717Val missense_variant 0.3
clpC1 4038558 p.Ile716Thr missense_variant 0.36
clpC1 4038587 c.2118C>G synonymous_variant 0.33
clpC1 4038596 p.Lys703Arg missense_variant 0.25
clpC1 4038740 c.1965G>C synonymous_variant 0.21
clpC1 4038743 c.1962G>C synonymous_variant 0.2
clpC1 4038749 c.1956C>T synonymous_variant 0.48
clpC1 4038755 c.1950G>C synonymous_variant 0.52
clpC1 4038764 c.1941C>T synonymous_variant 0.59
clpC1 4038773 c.1932T>C synonymous_variant 0.62
clpC1 4038779 c.1926C>G synonymous_variant 0.67
clpC1 4038794 p.Ser637Thr missense_variant 0.67
clpC1 4038810 p.Gln632Pro missense_variant 0.72
clpC1 4038812 c.1893T>C synonymous_variant 0.74
clpC1 4038849 p.Phe619Tyr missense_variant 0.19
clpC1 4038851 c.1854G>C synonymous_variant 0.19
clpC1 4038860 c.1845G>C synonymous_variant 0.79
clpC1 4038868 p.Lys613Gln missense_variant 0.26
clpC1 4038869 c.1836G>A synonymous_variant 0.27
clpC1 4038878 c.1827A>G synonymous_variant 0.49
clpC1 4038881 c.1824C>G synonymous_variant 0.32
clpC1 4038896 c.1809C>T synonymous_variant 0.3
clpC1 4038899 c.1806C>G synonymous_variant 0.22
clpC1 4038905 c.1800A>G synonymous_variant 0.5
clpC1 4038911 c.1794G>C synonymous_variant 0.42
clpC1 4038914 c.1791G>T synonymous_variant 0.39
clpC1 4038917 c.1788C>T synonymous_variant 0.15
clpC1 4038923 c.1780_1782delCTAinsTTG synonymous_variant 0.18
clpC1 4038929 c.1776G>C synonymous_variant 0.17
clpC1 4038939 p.Phe589Tyr missense_variant 0.15
clpC1 4038953 c.1752A>G synonymous_variant 0.16
clpC1 4038956 c.1749T>C synonymous_variant 0.17
clpC1 4038965 p.Ile580Val missense_variant 0.16
clpC1 4038971 c.1734T>C synonymous_variant 0.21
clpC1 4038974 c.1731T>G synonymous_variant 0.22
clpC1 4038983 p.Asp574Glu missense_variant 0.26
clpC1 4038989 c.1716T>C synonymous_variant 0.25
clpC1 4038997 c.1708T>C synonymous_variant 0.25
clpC1 4039001 p.Asn568Glu missense_variant 0.28
clpC1 4039007 c.1698G>C synonymous_variant 0.35
clpC1 4039018 p.Ser563Thr missense_variant 0.44
clpC1 4039022 c.1683A>G synonymous_variant 0.44
clpC1 4039028 c.1677G>A synonymous_variant 0.46
clpC1 4039046 c.1659C>G synonymous_variant 0.45
clpC1 4039067 c.1638G>C synonymous_variant 0.52
clpC1 4039070 c.1635G>C synonymous_variant 0.48
clpC1 4039073 c.1632C>A synonymous_variant 0.46
clpC1 4039079 c.1626C>G synonymous_variant 0.44
clpC1 4039082 c.1623C>T synonymous_variant 0.44
clpC1 4039085 c.1620A>G synonymous_variant 0.43
clpC1 4039090 c.1615C>T synonymous_variant 0.4
clpC1 4039091 c.1614G>C synonymous_variant 0.4
clpC1 4039106 c.1599G>C synonymous_variant 0.38
clpC1 4039117 p.Lys530Gln missense_variant 0.19
clpC1 4039427 c.1278G>A synonymous_variant 0.29
clpC1 4039439 c.1266C>T synonymous_variant 0.47
clpC1 4039442 c.1263A>G synonymous_variant 0.5
clpC1 4039448 c.1257A>G synonymous_variant 0.53
clpC1 4039454 c.1251A>G synonymous_variant 0.61
clpC1 4039463 c.1242C>G synonymous_variant 0.65
clpC1 4039466 c.1239T>C synonymous_variant 0.61
clpC1 4039469 c.1236T>C synonymous_variant 0.58
clpC1 4039472 c.1233G>C synonymous_variant 0.6
clpC1 4039481 c.1224T>G synonymous_variant 0.6
clpC1 4039484 c.1221T>C synonymous_variant 0.6
clpC1 4039487 c.1218G>C synonymous_variant 0.5
clpC1 4039508 c.1197G>C synonymous_variant 0.48
clpC1 4039517 c.1188C>G synonymous_variant 0.48
clpC1 4039524 p.Phe394Tyr missense_variant 0.46
clpC1 4039541 c.1164C>G synonymous_variant 0.26
clpC1 4039547 c.1158C>G synonymous_variant 0.19
clpC1 4039553 c.1152C>G synonymous_variant 0.13
clpC1 4039556 c.1149G>C synonymous_variant 0.12
clpC1 4039616 c.1089G>C synonymous_variant 0.29
clpC1 4039622 c.1083C>G synonymous_variant 0.33
clpC1 4039645 p.His354Asp missense_variant 0.26
clpC1 4039646 p.Glu353Ala missense_variant 0.32
clpC1 4039649 c.1056G>C synonymous_variant 0.29
clpC1 4039652 p.Thr351Asn missense_variant 0.29
clpC1 4039660 p.Glu349Gln missense_variant 0.35
clpC1 4039661 p.Gly348Asp missense_variant 0.34
clpC1 4039664 c.1041G>C synonymous_variant 0.34
clpC1 4039668 p.Gln346Met missense_variant 0.38
clpC1 4039670 p.Val345Ile missense_variant 0.31
clpC1 4039682 c.1023C>T synonymous_variant 0.28
clpC1 4039685 c.1020C>G synonymous_variant 0.28
clpC1 4039694 c.1011G>C synonymous_variant 0.28
clpC1 4039697 p.Ala336Pro missense_variant 0.72
clpC1 4039711 p.Ile332Val missense_variant 0.27
clpC1 4039724 c.981A>G synonymous_variant 0.78
clpC1 4039730 c.975C>G synonymous_variant 0.39
clpC1 4039733 c.972G>C synonymous_variant 0.8
clpC1 4039742 c.963C>T synonymous_variant 0.43
clpC1 4039748 p.Thr319Ser missense_variant 0.67
clpC1 4039751 c.954A>G synonymous_variant 0.62
clpC1 4039757 c.948A>G synonymous_variant 0.48
clpC1 4039760 c.945T>C synonymous_variant 0.52
clpC1 4039766 c.939T>C synonymous_variant 0.61
clpC1 4039769 c.936C>G synonymous_variant 0.52
clpC1 4039773 p.Lys311Met missense_variant 0.63
clpC1 4039778 c.927A>G synonymous_variant 0.62
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.62
clpC1 4039817 c.888A>C synonymous_variant 0.52
clpC1 4039820 c.885T>C synonymous_variant 0.52
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.45
clpC1 4039838 p.Leu289Ile missense_variant 0.52
clpC1 4039850 c.855T>C synonymous_variant 0.61
clpC1 4039855 p.Leu284Met missense_variant 0.55
clpC1 4039865 c.840T>C synonymous_variant 0.6
clpC1 4039875 p.Asn277Arg missense_variant 0.57
clpC1 4039898 c.807C>G synonymous_variant 0.58
clpC1 4039901 c.804C>G synonymous_variant 0.57
clpC1 4039904 c.801A>G synonymous_variant 0.57
clpC1 4039907 c.798G>A synonymous_variant 0.59
clpC1 4039916 c.789T>C synonymous_variant 0.64
clpC1 4039929 c.775_776delAGinsTC synonymous_variant 0.52
clpC1 4039934 c.771G>C synonymous_variant 0.5
clpC1 4039946 c.759A>T synonymous_variant 0.33
clpC1 4039949 c.756G>C synonymous_variant 0.3
clpC1 4039952 c.753T>C synonymous_variant 0.28
clpC1 4039955 c.750G>C synonymous_variant 0.29
clpC1 4039958 c.747G>C synonymous_variant 0.31
clpC1 4039967 p.Gln246His missense_variant 0.33
clpC1 4039994 p.Glu237Asp missense_variant 0.13
clpC1 4040001 p.His235Arg missense_variant 0.21
clpC1 4040003 c.702G>C synonymous_variant 0.27
clpC1 4040015 c.690G>C synonymous_variant 0.64
clpC1 4040024 c.681A>G synonymous_variant 0.67
clpC1 4040033 c.672G>C synonymous_variant 0.62
clpC1 4040084 c.621C>G synonymous_variant 0.44
clpC1 4040087 c.618G>T synonymous_variant 0.41
clpC1 4040090 c.615T>C synonymous_variant 0.44
clpC1 4040093 c.612C>G synonymous_variant 0.44
clpC1 4040257 p.Ala150Ser missense_variant 0.25
clpC1 4040267 c.438A>G synonymous_variant 0.33
clpC1 4040271 p.Tyr145Phe missense_variant 0.33
clpC1 4040273 c.432T>C synonymous_variant 0.3
clpC1 4040279 c.426C>G synonymous_variant 0.45
clpC1 4040288 p.Ile139Leu missense_variant 0.4
clpC1 4040291 c.414G>A synonymous_variant 0.4
clpC1 4040308 c.397C>A synonymous_variant 0.68
clpC1 4040311 p.Thr132Ser missense_variant 0.68
clpC1 4040315 p.Glu130Asp missense_variant 0.69
clpC1 4040324 c.381G>C synonymous_variant 0.68
clpC1 4040348 c.357G>C synonymous_variant 0.67
clpC1 4040351 c.354C>T synonymous_variant 0.68
clpC1 4040357 c.348T>C synonymous_variant 0.65
clpC1 4040363 c.342A>C synonymous_variant 0.61
clpC1 4040375 c.330G>C synonymous_variant 0.61
clpC1 4040380 c.325T>C synonymous_variant 0.58
clpC1 4040387 c.318A>G synonymous_variant 0.59
clpC1 4040393 c.312G>C synonymous_variant 0.54
clpC1 4040411 c.294T>C synonymous_variant 0.42
clpC1 4040414 c.291G>A synonymous_variant 0.44
clpC1 4040423 c.282A>G synonymous_variant 0.31
clpC1 4040426 c.279T>C synonymous_variant 0.27
clpC1 4040431 c.274T>C synonymous_variant 0.25
clpC1 4040441 c.264C>G synonymous_variant 0.21
clpC1 4040444 c.261C>G synonymous_variant 0.21
clpC1 4040450 c.255A>G synonymous_variant 0.2
clpC1 4040456 c.249C>G synonymous_variant 0.2
clpC1 4040459 c.246C>G synonymous_variant 0.2
clpC1 4040465 c.240T>C synonymous_variant 0.21
clpC1 4040471 c.234T>C synonymous_variant 0.21
clpC1 4040618 c.87C>T synonymous_variant 0.39
clpC1 4040644 c.61A>C synonymous_variant 0.37
clpC1 4040654 c.51G>A synonymous_variant 0.35
clpC1 4040657 c.48T>C synonymous_variant 0.35
clpC1 4040669 c.36C>T synonymous_variant 0.33
clpC1 4040674 c.31A>C synonymous_variant 0.35
clpC1 4040681 c.24T>G synonymous_variant 0.32
clpC1 4040690 c.15T>C synonymous_variant 0.33
clpC1 4040693 c.12A>G synonymous_variant 0.33
clpC1 4040699 c.6C>T synonymous_variant 0.29
panD 4044034 c.247delG frameshift_variant 0.15
embC 4241212 c.1350G>A synonymous_variant 0.14
embC 4241466 p.Phe535Tyr missense_variant 0.14
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242836 p.Pro992Thr missense_variant 0.2
embA 4243460 c.228C>T synonymous_variant 1.0
embA 4244467 p.Ile412Thr missense_variant 0.15
aftB 4267647 p.Asp397Gly missense_variant 1.0
whiB6 4338410 c.111delT frameshift_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 1.0