Run ID: SRR28119827
Sample name:
Date: 2025-02-11T16:59:18.448315
Number of reads: 298653
Percentage reads mapped: 36.98
Median coverage: 0.0
Strain: La3;lineage4.9
Spoligotype:
Drug-resistance: Other
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage6.1.3 | West-Africa 2 | RD702 | 0.13 |
| lineage4 | Euro-American | None | 0.96 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.97 |
| La3 | M.orygis | None | 0.13 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | embB | p.Tyr384Asn | Mutation from literature | |
| pyrazinamide | ||||
| streptomycin | ||||
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | ||||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| embB | 4247663 | p.Tyr384Asn | missense_variant | 1.0 | ethambutol | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 795 | c.795A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 802 | c.802C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 805 | c.805_807delTTGinsCTC | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 813 | c.813C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 822 | c.822A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 828 | c.828T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 840 | c.840G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 843 | c.843T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 849 | c.849A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 852 | c.852G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| gyrB | 5341 | c.102T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5362 | c.123T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5363 | c.124_126delTTAinsCTG | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5404 | c.165C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5410 | c.171G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5422 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5425 | c.186A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5426 | p.Thr63Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5431 | c.192A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5434 | c.195G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5436 | p.Asn66Thr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5440 | c.201A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5449 | c.210T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6016 | c.777C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6022 | c.783G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6025 | c.786A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6046 | c.807C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6049 | c.810G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6052 | c.813T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6067 | c.828G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6073 | c.834T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6079 | c.840C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6086 | p.Thr283Pro | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6091 | c.852G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6115 | c.876A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6121 | c.882C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6130 | c.891T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6139 | c.900G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6602 | c.-700C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6610 | c.-692C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6613 | c.-689A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6616 | c.-686A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6622 | c.-680C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6634 | c.-668T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6637 | c.-665T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6640 | c.-662A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6643 | c.-659A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6649 | c.-653T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6655 | c.-647T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6670 | c.-632G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6673 | c.-629A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6676 | c.-626T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6680 | c.1441C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6703 | c.-599G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6712 | c.-590G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6728 | c.-574_-572delCTAinsTTG | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6745 | c.1506T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6769 | c.-533C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7317 | c.16T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7325 | c.24T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7331 | c.30C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7334 | c.33G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7335 | p.Leu12Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7340 | p.Asp13Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7349 | c.48A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7355 | c.54T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7361 | c.60C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7391 | c.90C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7406 | c.105G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7421 | c.120G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7430 | c.129G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7442 | c.141G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7460 | c.159C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7463 | c.162G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7469 | c.168C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7472 | c.171T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7487 | c.186C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7490 | c.189C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7496 | c.195C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7502 | c.201C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7619 | c.318C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7622 | c.321C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7637 | c.336C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7652 | c.351C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7658 | c.357A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7664 | c.363T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7667 | c.366C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7683 | c.382_384delAGGinsCGC | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7694 | c.393A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7710 | c.409T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7715 | c.414G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7728 | c.427_429delAGGinsCGT | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7763 | c.462T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7778 | c.477G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7784 | c.483A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7787 | c.486G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7799 | c.498A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7832 | c.531G>T | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7835 | c.534A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7850 | c.549C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7859 | c.558A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8264 | c.963T>C | synonymous_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8267 | c.966G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8283 | p.Ile328Leu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8288 | c.987T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8294 | c.993T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8306 | c.1005C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8310 | c.1009C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8318 | c.1017C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8339 | c.1038A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8340 | p.Ala347Ser | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8375 | c.1074G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 8382 | p.Leu361Met | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8393 | c.1092T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8399 | c.1098T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8402 | p.Asp367Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8981 | c.1680G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9002 | c.1701C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9003 | c.1702C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9029 | c.1728T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9032 | c.1731T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9050 | p.Asp583Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| Rv0010c | 13846 | c.-288G>C | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13852 | c.-294A>G | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13858 | c.-302_-300delATCinsGTG | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13864 | c.-306A>C | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13878 | c.-320C>T | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13879 | c.-321T>G | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13882 | c.-324C>T | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13903 | c.-345A>G | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13906 | c.-348C>T | upstream_gene_variant | 1.0 | isoniazid | |
| Rv0010c | 13909 | c.-351G>C | upstream_gene_variant | 1.0 | isoniazid | |
| fgd1 | 491142 | c.360C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491144 | p.Ala121Val | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491163 | c.381G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491181 | c.399T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491191 | p.Gly137Arg | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491196 | c.414A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491202 | c.420G>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491203 | p.Gln141Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491208 | c.426G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491212 | p.Ser144Arg | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491217 | c.435T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491223 | c.441C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491226 | c.444C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491229 | c.447C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491232 | c.450T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491241 | p.Asp153Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491244 | c.462T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491262 | c.480C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491283 | p.Asp167Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491286 | c.504G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fgd1 | 491295 | c.513C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fgd1 | 491493 | c.711C>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491499 | c.717G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491508 | c.726A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491512 | p.Asn244Gln | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491526 | c.744T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491542 | c.760T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491547 | c.765A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491550 | c.768T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491604 | c.822G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491610 | c.828A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491616 | c.834A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491643 | c.861G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491646 | c.864G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491652 | c.870C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491658 | c.876A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| Rv0565c | 657689 | c.-220_-219delCAinsAG | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657728 | c.-258C>T | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 1.0 | ethionamide | |
| hadA | 732295 | c.366G>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732308 | p.Val127Ile | missense_variant | 1.0 | isoniazid | |
| hadA | 732317 | p.Glu130Asn | missense_variant | 1.0 | isoniazid | |
| hadA | 732322 | p.Glu131Asp | missense_variant | 1.0 | isoniazid | |
| hadA | 732329 | p.Leu134Ile | missense_variant | 1.0 | isoniazid | |
| hadA | 732346 | c.417T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732355 | c.426G>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732361 | c.432C>G | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732378 | c.449_450insGGA | disruptive_inframe_insertion | 1.0 | isoniazid | |
| hadA | 732391 | c.462T>A | synonymous_variant | 1.0 | isoniazid | |
| rpoB | 760059 | p.Tyr85Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 760067 | c.261G>T | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 760070 | c.264T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760082 | c.276C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760091 | c.285G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760101 | c.295T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760106 | c.300G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760112 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760118 | c.312T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760121 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760124 | c.318C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760136 | c.330G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760142 | c.336C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760172 | c.366G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760178 | c.372G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760181 | c.375T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760193 | c.387C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760202 | c.396G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760211 | c.405C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760223 | c.417T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760304 | c.498G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760307 | c.501T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760325 | c.519G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760328 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760343 | c.537G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761030 | c.1224G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761132 | c.1326G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761153 | c.1347G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761165 | c.1359G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761175 | c.1369C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761180 | c.1374A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761189 | c.1383T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761201 | c.1395G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761204 | c.1398C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761207 | c.1401C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761210 | c.1404C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761240 | c.1434C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761264 | c.1458C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761273 | c.1467T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761318 | c.1512G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761600 | c.1794T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761612 | c.1806G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761651 | c.1845C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761657 | c.1851C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761682 | c.1876C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761687 | c.1881C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761693 | c.1887G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761721 | c.1917delA | frameshift_variant | 1.0 | rifampicin | |
| rpoB | 761727 | p.Ser641Val | missense_variant | 1.0 | rifampicin | |
| rpoB | 761732 | c.1926delCinsGG | frameshift_variant&synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761735 | c.1929C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761765 | c.1959T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761791 | p.Arg662His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761819 | c.2013G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761822 | c.2016C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761848 | p.Cys681Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761864 | c.2058G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761867 | c.2061C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761873 | c.2067A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761885 | c.2079T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761891 | c.2085G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761906 | c.2100C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761912 | c.2106T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761913 | p.Asp703Gln | missense_variant | 1.0 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761972 | c.2166C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761990 | c.2184G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762410 | c.-960T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762449 | c.-921C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762470 | c.2664G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762482 | c.-888C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762485 | c.2679G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762486 | p.Pro894Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 762489 | p.Val895Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 762509 | c.-861T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762510 | p.Ala902Pro | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 762518 | c.-852C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762521 | c.-849C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762929 | c.3123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762995 | c.3189G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763028 | c.3222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763034 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763696 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763702 | c.333C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763708 | c.339G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763714 | c.345G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763732 | c.363C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763735 | c.366G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763744 | c.375G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763765 | c.396T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763774 | c.405G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763781 | p.Ser138Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763813 | c.444C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763819 | c.450G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763855 | c.486C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763867 | c.498C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763872 | p.Gly168Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 763876 | p.Glu169Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763882 | c.513G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763885 | c.516C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763888 | c.519G>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763891 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763904 | p.Ala179Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 763916 | p.Glu183Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 763945 | c.576T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763948 | c.579G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763987 | c.618C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763991 | p.Ile208Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 763996 | c.627T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764005 | c.636G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764011 | c.642T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764024 | c.655T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764040 | p.Ser224Asn | missense_variant | 1.0 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764062 | c.693C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764578 | c.1209C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764585 | c.1216_1218delCTCinsTTG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764611 | c.1242G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764893 | c.1524T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764902 | c.1533C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764918 | p.Val517Ile | missense_variant | 1.0 | rifampicin | |
| rpoC | 764923 | c.1554A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764932 | c.1563C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764938 | c.1569G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765007 | c.1638T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765011 | c.1642_1643delAGinsTC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765022 | c.1653G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765034 | c.1665T>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765052 | c.1683C>A | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 765076 | c.1707A>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765079 | c.1710T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765082 | c.1713G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765085 | c.1716T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765383 | p.Met672Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765405 | p.Leu679Pro | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765409 | c.2040T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765421 | c.2052C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765445 | c.2076G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765454 | c.2085C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765496 | c.2127C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765526 | c.2157C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765784 | c.2415C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765814 | c.2445A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765826 | c.2457T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765850 | c.2481G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765883 | c.2514C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765934 | c.2565C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766351 | c.2982C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766357 | c.2988C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766360 | c.2991C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766375 | c.3006C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766378 | c.3009C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766387 | c.3018C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766397 | c.3028C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766408 | c.3039C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766447 | c.3078T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766456 | c.3087C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766486 | c.3117A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766528 | c.3159T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766534 | c.3165C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766537 | c.3168G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766543 | c.3174C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766645 | c.3276A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766654 | c.3285C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766666 | c.3297C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766741 | c.3372G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766747 | c.3378C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766792 | c.3423C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766798 | c.3429C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766801 | c.3432C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766843 | c.3474T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766894 | c.3525T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766895 | c.3526T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766907 | c.3538C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766915 | c.3546C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766918 | c.3549C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766921 | c.3552G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766933 | c.3564A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766972 | c.3603G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767032 | c.3663G>T | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 767035 | c.3666G>T | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 767059 | c.3690T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767062 | c.3693C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767086 | c.3717C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767167 | c.3798C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767170 | c.3801C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767203 | c.3834C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rplC | 800648 | c.-161A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800693 | c.-116A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800714 | c.-95C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800720 | c.-89T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800723 | c.-86C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800726 | c.-83G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800729 | c.-80G>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800735 | c.-74C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800744 | c.-65G>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800759 | c.-50C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800796 | c.-13A>T | upstream_gene_variant | 0.98 | linezolid | |
| rplC | 800797 | c.-12T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800799 | c.-9_-8delGA | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800844 | c.36T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800865 | c.57A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800867 | p.Ser20Asn | missense_variant | 1.0 | linezolid | |
| rplC | 800877 | c.69A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800889 | c.81C>A | synonymous_variant | 1.0 | linezolid | Not assoc w R - Interim |
| rplC | 800901 | c.93C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800904 | c.96G>C | synonymous_variant | 0.82 | linezolid | |
| fbiC | 1304856 | c.1926C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304868 | c.1938G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304875 | p.Ile649Val | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304893 | p.Gly655Ser | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| rrs | 1471922 | n.78delT | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1471931 | n.87delA | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471984 | n.139T>A | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1471985 | n.140T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472307 | n.462C>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrl | 1473417 | n.-241C>T | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473419 | n.-239T>C | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473421 | n.-237G>A | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473437 | n.-221T>C | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473449 | n.-209G>A | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473648 | n.-9_-7delTTG | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473731 | n.74T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473832 | n.175C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474286 | n.630delT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474292 | n.636_649delTCCTCTCCGGAGGA | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474374 | n.717T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474376 | n.719T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474417 | n.760A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474424 | n.767_771delCATACinsT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474430 | n.773C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474437 | n.781_782delAA | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474673 | n.1016T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474717 | n.1060A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474794 | n.1137C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474950 | n.1293G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474952 | n.1296_1300delCATCC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474961 | n.1304T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474962 | n.1305T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474964 | n.1307T>A | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
| linezolid | ||||||
| rrl | 1474967 | n.1311_1315delGGGTG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475006 | n.1349A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475028 | n.1371G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475369 | n.1712G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475401 | n.1745delC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475603 | n.1946G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475638 | n.1981C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475758 | n.2104delC | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476035 | n.2378G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476095 | n.2438C>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
| linezolid | ||||||
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476117 | n.2460G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476214 | n.2557G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476297 | n.2640C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476299 | n.2642C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476529 | n.2872A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476580 | n.2923G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| inhA | 1673658 | c.-544G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673660 | c.-542C>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673664 | c.-538A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673667 | c.-535A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673685 | c.-517C>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673697 | c.-505G>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673710 | c.-492_-490delCTAinsGTG | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673721 | c.-481C>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673724 | c.-478A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673730 | c.-472C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673733 | c.-469G>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673736 | c.-466G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673748 | c.-454A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673749 | c.-453_-452delAAinsCG | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673766 | c.-436C>T | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| inhA | 1673767 | c.-435A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673797 | c.-405G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673802 | c.-400A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673809 | c.-393_-391delTCGinsGCT | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673826 | c.-376C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673829 | c.-373C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673832 | c.-370A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673838 | c.-364T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673841 | c.-361A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673842 | c.-360A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673847 | c.-355A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673849 | c.-353T>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673853 | c.-349A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673859 | c.-343G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673871 | c.-331C>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673892 | c.-310C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673901 | c.-301A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673916 | c.-286A>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674489 | c.288G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674501 | c.300G>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674503 | p.Thr101Ser | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674513 | c.312C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674542 | p.Ala114Glu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674546 | c.345T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674558 | c.357C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674570 | c.369G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674576 | c.375T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674579 | c.378G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674582 | c.381T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674594 | c.393C>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674609 | c.408G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674618 | c.417C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674620 | p.Pro140His | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674624 | c.423A>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674627 | c.426T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674924 | c.723G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674927 | c.726G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674942 | c.741T>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674945 | p.Asp248Glu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674954 | c.753G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674977 | p.Tyr259Phe | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674993 | c.792G>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1675002 | c.801A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| rpsA | 1833661 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833664 | c.123C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833703 | c.162C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833727 | c.186G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833745 | c.204G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833754 | c.213G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833772 | c.231C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833790 | c.249T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833793 | c.252C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833799 | c.258C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833805 | c.264C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833806 | c.265C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833811 | c.270G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833817 | c.276C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834063 | c.522C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834090 | c.549G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834096 | c.555G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834099 | c.558C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834102 | c.561T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834105 | c.564C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834123 | c.582C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834129 | c.588C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834144 | c.603G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834150 | c.609G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834153 | c.612T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834162 | c.621A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834165 | c.624A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834186 | c.645C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834189 | c.648G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834195 | c.654G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834213 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834222 | c.681T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834225 | c.684C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834231 | c.690T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834241 | c.700C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834252 | c.711C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834282 | c.741C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834285 | c.744G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834300 | c.759G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834330 | c.789C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834360 | c.819G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834375 | c.834G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834390 | c.849G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834396 | c.855G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834408 | c.867C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834414 | c.873C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834417 | c.876G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834465 | c.924T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834477 | c.936C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834495 | c.954G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834498 | c.957C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834528 | c.987T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834534 | c.993C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834543 | c.1002C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834558 | c.1017C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834570 | c.1029C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834574 | p.Met345Leu | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834585 | c.1044C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834627 | c.1086C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834657 | c.1116G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834663 | c.1122C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834669 | c.1128G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834733 | p.Ala398Pro | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834738 | p.Glu399Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834747 | c.1206A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834751 | p.Leu404Met | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834756 | c.1215G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834765 | p.Glu408Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834766 | p.Lys409Ala | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834775 | p.Ala412Thr | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834789 | c.1248T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834792 | c.1251G>C | synonymous_variant | 1.0 | pyrazinamide | |
| tsnR | 1853611 | c.6C>T | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1853632 | c.27G>T | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1853636 | p.Thr11Ala | missense_variant | 1.0 | linezolid | Uncertain significance |
| tsnR | 1853648 | c.43C>T | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1853656 | c.51T>C | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1853662 | c.57A>T | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1853671 | c.66C>T | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1853674 | c.69G>T | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1853679 | p.Gly25Asp | missense_variant | 1.0 | linezolid | |
| tsnR | 1853683 | c.78T>A | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1853695 | c.90A>G | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1853710 | c.105A>C | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1853712 | p.Ala36Glu | missense_variant | 1.0 | linezolid | |
| tsnR | 1853721 | p.Leu39Ser | missense_variant | 1.0 | linezolid | |
| tsnR | 1853737 | c.132A>G | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1853749 | c.144C>T | synonymous_variant | 1.0 | linezolid | Not assoc w R - Interim |
| katG | 2155683 | c.429G>A | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155691 | c.421T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155695 | c.417C>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155704 | c.408C>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155716 | c.396T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155722 | c.390G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2517941 | c.-174C>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517956 | c.-159G>A | upstream_gene_variant | 0.97 | isoniazid | |
| kasA | 2517974 | c.-141T>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518714 | c.600A>T | synonymous_variant | 0.9 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518783 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518789 | c.675G>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518795 | c.681C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518813 | c.699C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518816 | c.702C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518822 | c.708C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518847 | c.733C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518855 | c.741C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518856 | p.Ile248Leu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518864 | c.750G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518879 | c.765A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518885 | c.771T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518891 | c.777C>T | synonymous_variant | 1.0 | isoniazid | |
| Rv2477c | 2782861 | c.1182T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782864 | c.1179T>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782873 | c.1170C>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2782876 | c.1167G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782882 | c.1161T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782897 | c.1146G>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782905 | p.Val380Ile | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782912 | p.Ser377Thr | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782928 | p.Thr372Glu | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782930 | c.1113G>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782948 | c.1095A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783587 | c.456G>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783593 | c.450T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783602 | c.441G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783605 | c.438T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783611 | c.432C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783620 | c.423C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783623 | c.420G>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783629 | c.414C>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783632 | c.411C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783658 | c.385C>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783660 | p.Glu128Val | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783665 | c.378A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783668 | c.375G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783671 | c.372G>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783674 | c.369T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783683 | c.360A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783691 | c.352C>T | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783737 | c.306C>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783751 | p.Ile98Val | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783766 | p.Met93Leu | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783776 | c.267G>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783779 | c.264T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783785 | c.258C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783791 | c.252C>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2681 | 2996951 | c.213C>T | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2996957 | c.219T>C | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2996974 | p.Glu79Gly | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2997014 | c.276T>C | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997021 | p.Leu95Pro | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2997024 | p.Thr96Ala | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2997035 | c.297G>A | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| Rv2681 | 2997056 | p.Ser106Arg | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2997057 | p.Thr107Asp | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2997060 | p.Asn108Asp | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2997071 | c.333C>T | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997098 | c.360C>G | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997104 | c.366C>G | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997116 | c.378T>C | synonymous_variant | 1.0 | capreomycin | |
| thyX | 3067230 | p.Thr239Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067247 | c.699C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067250 | c.696G>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067280 | c.666G>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067284 | p.Ala221Asp | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067288 | p.Ala220Thr | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067295 | c.651C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067304 | c.642A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067316 | c.630A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067325 | c.621A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067337 | c.609C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067355 | c.591A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073953 | c.519T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073956 | c.516G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073959 | c.513T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073977 | c.495A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073989 | c.483T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074001 | c.471C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074004 | c.468T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074031 | c.441T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074034 | c.438T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074037 | c.435C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074040 | c.432G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074053 | p.Arg140Gln | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074056 | p.Glu139Pro | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074061 | p.Glu137Asp | missense_variant | 1.0 | para-aminosalicylic_acid | |
| lpqB | 3623942 | c.969A>T | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3623946 | p.Asn322Gly | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3623953 | c.958T>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3623962 | c.949T>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3623963 | c.948G>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3623970 | p.Ala314Gly | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3623975 | c.936T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3623978 | c.933C>T | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624002 | c.909G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| lpqB | 3624008 | c.903T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3624014 | c.897T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3624018 | p.Thr298Asn | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624023 | c.888G>A | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624029 | c.882C>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624032 | c.879T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| lpqB | 3624041 | p.Glu290Asp | missense_variant | 0.97 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624044 | c.867G>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624080 | c.831G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| lpqB | 3624092 | c.819G>A | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624101 | c.810C>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624107 | c.804C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3624629 | c.282G>A | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624646 | c.265T>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624650 | c.261G>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624662 | c.249C>T | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624680 | c.231T>A | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624686 | p.Glu75Gln | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624692 | c.219C>T | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624704 | c.207G>A | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624707 | c.204G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3624713 | c.198C>T | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624734 | c.177A>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624749 | c.162G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3624755 | c.154_156delTTAinsCTG | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624767 | c.144C>A | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624776 | c.135T>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625510 | c.-600T>G | upstream_gene_variant | 0.9 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625518 | c.-608T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625522 | c.-612C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625531 | c.-621C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625537 | c.-627T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625569 | c.1045T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625570 | p.Thr348Ser | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625587 | c.-677C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625606 | c.-696C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625630 | c.-720C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625648 | c.-738T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625720 | c.894G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625747 | c.867G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625750 | c.864G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625755 | p.Ala287Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| bedaquiline | ||||||
| lpqB | 3625803 | c.-893C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625804 | c.-896_-894delAGGinsCGA | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625807 | c.807C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625819 | c.795G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626194 | c.420T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626206 | c.408T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mtrB | 3626215 | c.399G>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626245 | p.Leu123Gln | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626250 | p.Gly122Ser | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626251 | p.Ala121Thr | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626254 | c.360G>T | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626257 | c.357G>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626260 | c.354T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mtrB | 3626266 | c.348C>T | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626278 | c.336G>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626284 | c.330T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626296 | c.318T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626308 | c.306T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626317 | c.297A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626357 | p.Thr86Asn | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626359 | c.255C>A | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626362 | c.252A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626372 | p.Ile81Thr | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626386 | c.228G>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626390 | p.Arg75Lys | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626394 | p.Val74Leu | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626407 | c.207C>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626410 | c.204T>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626413 | c.201T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626437 | c.177T>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626455 | c.159C>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626461 | c.153A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626467 | c.147G>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626473 | c.141T>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626476 | c.138C>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626485 | c.129G>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626491 | c.123G>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626497 | c.117G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626502 | c.112C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626518 | c.96C>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626521 | c.93T>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626524 | c.90A>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626912 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626939 | p.Glu137Asp | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626954 | c.-341C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626959 | c.-346C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626969 | c.-356C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626996 | c.-383G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627008 | c.-395G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627011 | c.-398T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627065 | c.-452G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627071 | c.279G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3627080 | c.270T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627098 | c.252A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627128 | c.-515T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627131 | p.Ala73Ser | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627134 | c.-521C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627137 | c.-526_-524delTTGinsCTC | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627143 | c.-530G>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627146 | c.204C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627149 | c.-536G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627155 | c.-542C>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627185 | c.-574_-572delTTGinsCTC | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627188 | c.-577_-575delTTAinsCTG | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627227 | c.123T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| alr | 3840206 | c.1215T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840230 | c.1191T>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840233 | c.1188A>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840236 | c.1185A>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840275 | c.1146T>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840293 | c.1128T>A | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840296 | c.1125G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840305 | c.1116T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840308 | c.1113G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840312 | p.Ile370Thr | missense_variant | 1.0 | cycloserine | |
| alr | 3840317 | c.1104G>T | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840328 | c.1093T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840332 | c.1089G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840353 | c.1068T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840356 | p.Leu355Ile | missense_variant | 1.0 | cycloserine | |
| alr | 3840360 | p.Pro354Arg | missense_variant | 1.0 | cycloserine | |
| alr | 3840362 | c.1059G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840371 | c.1050G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840380 | p.Met347Val | missense_variant | 1.0 | cycloserine | |
| alr | 3840461 | c.960G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840476 | c.945A>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840482 | c.939T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840502 | p.Leu307Val | missense_variant | 1.0 | cycloserine | |
| alr | 3840503 | p.Asn306Thr | missense_variant | 0.97 | cycloserine | |
| alr | 3840512 | c.909C>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840515 | c.906A>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840527 | c.894A>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840536 | c.885T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840548 | c.873G>A | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840551 | c.870G>A | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840557 | p.Arg288Pro | missense_variant | 1.0 | cycloserine | |
| alr | 3840562 | p.Ile287Val | missense_variant | 1.0 | cycloserine | |
| alr | 3840569 | c.852G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840572 | c.849G>A | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840575 | c.846G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840578 | c.843T>A | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840584 | c.837T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840611 | c.810G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840617 | p.Asp268Glu | missense_variant | 1.0 | cycloserine | |
| rpoA | 3877704 | c.804G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877710 | c.798C>T | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877731 | c.777G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877734 | c.774G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877737 | c.771G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877758 | c.750G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877770 | c.738A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877773 | c.735G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877776 | c.732T>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877829 | p.Val227Ile | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877830 | c.678C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877836 | c.672A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877839 | c.669G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877848 | c.660C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877875 | c.633T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878157 | c.351C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878163 | c.345C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878202 | c.306G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878247 | c.261G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878256 | c.252G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878259 | c.249G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878837 | c.-330A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878842 | c.-335G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878909 | c.-402A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878920 | c.-413C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878938 | c.-431T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878946 | c.-439C>A | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878956 | c.-449G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878962 | c.-455G>C | upstream_gene_variant | 1.0 | rifampicin | |
| clpC1 | 4038200 | c.2505T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038212 | c.2493T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038239 | c.2466T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038257 | c.2448G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038260 | c.2445C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038271 | p.Pro812Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038272 | c.2433T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038302 | c.2403C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038308 | c.2397G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038314 | c.2391T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038335 | c.2370C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038347 | c.2358G>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4038350 | c.2355C>G | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4038356 | c.2349T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038359 | c.2346A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038456 | p.Val750Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038499 | p.Ser736Gly | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038519 | p.Arg729Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038527 | c.2178G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038530 | p.Glu725Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038551 | c.2154C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038602 | c.2103G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038653 | c.2052C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038689 | c.2016C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038695 | c.2010C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038698 | c.2007C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038707 | c.1998C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038755 | c.1950G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038785 | c.1920G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038790 | c.1915C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038838 | c.1867C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038839 | c.1866G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038845 | c.1858_1860delTCGinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038854 | c.1851G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038881 | c.1824C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038902 | c.1803C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038917 | c.1788C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038923 | c.1782A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039034 | c.1671C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039037 | c.1668T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039046 | c.1659C>A | synonymous_variant | 0.99 | pyrazinamide | |
| clpC1 | 4039058 | c.1647C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039079 | c.1626C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039091 | c.1614G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039100 | c.1605C>T | synonymous_variant | 0.99 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039115 | c.1590G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039118 | c.1587C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039163 | c.1542G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039178 | c.1527G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039186 | c.1519C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039226 | c.1479T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039238 | c.1467C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039244 | c.1461G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039271 | c.1434G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039286 | c.1419T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039292 | c.1413C>G | synonymous_variant | 0.99 | pyrazinamide | |
| clpC1 | 4039319 | c.1386T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039322 | c.1383T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039328 | c.1377A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039334 | c.1371G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039337 | c.1368A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039349 | c.1356C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039352 | c.1353C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039391 | c.1314T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039409 | c.1296T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039412 | c.1293T>G | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039430 | c.1275T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039442 | c.1263A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039448 | c.1257A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039454 | c.1251A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039463 | c.1242C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039466 | c.1239T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039469 | c.1236T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039481 | c.1224T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039484 | c.1221T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039487 | c.1218G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039661 | c.1044T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039664 | c.1041G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039667 | c.1038G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039694 | c.1011G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039706 | c.999G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039724 | c.981A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039754 | c.951G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039769 | c.936C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039778 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039781 | c.924G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039784 | c.921C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039787 | c.916_918delTCGinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039793 | c.912C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039802 | c.903G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039814 | c.891C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039817 | c.888A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039820 | c.885T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039826 | c.879C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039831 | c.874T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039855 | c.850C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040036 | c.669C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040042 | c.663C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040048 | c.657C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040090 | c.615T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040105 | c.600C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040147 | c.558A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040165 | c.540G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040168 | c.537G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040171 | c.534C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040201 | c.504C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040204 | c.501G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040207 | c.498T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040215 | p.Ser164Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040219 | c.486C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040225 | c.480A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040228 | c.477G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040231 | c.474C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040234 | c.471C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040240 | c.465C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040249 | c.456A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040267 | c.438A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040273 | c.432T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040279 | c.426C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040300 | c.405C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040330 | c.375C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040336 | c.369G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040342 | c.363C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040345 | c.360C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040348 | c.357G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040351 | c.354C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040354 | c.351A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040363 | c.342A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040380 | c.325T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040381 | c.324T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040423 | c.282A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| embC | 4240693 | c.831T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240703 | c.841C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240717 | c.855T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240726 | c.864G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240741 | c.879C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240777 | c.915G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240780 | c.918T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240783 | c.921G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240789 | c.927T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240795 | c.933C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240801 | c.939C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241279 | p.Val473Leu | missense_variant | 1.0 | ethambutol | |
| embC | 4241288 | p.Ile476Leu | missense_variant | 1.0 | ethambutol | |
| embC | 4241293 | c.1431G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4242277 | c.-956T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242283 | c.2421T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4242287 | p.Leu809Ile | missense_variant | 0.97 | ethambutol | |
| embC | 4242305 | p.Ile815Phe | missense_variant | 1.0 | ethambutol | |
| embC | 4242315 | p.Ser818Thr | missense_variant | 1.0 | ethambutol | |
| embC | 4242320 | p.Pro820Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4242334 | c.-899G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242343 | c.-890G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242355 | c.-878A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242384 | p.Tyr841Phe | missense_variant | 1.0 | ethambutol | |
| embA | 4242397 | c.-836G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242403 | c.-830T>A | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242406 | c.2544A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4242434 | p.Val858Ile | missense_variant | 1.0 | ethambutol | |
| embA | 4242442 | c.-791G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242445 | c.-788C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242448 | c.-785C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242449 | p.Met863Leu | missense_variant | 1.0 | ethambutol | |
| embA | 4242454 | c.-779G>T | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242823 | c.-410G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245125 | c.1893G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245137 | c.1905T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245149 | c.1917C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245182 | c.1950T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245185 | c.1953G>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245186 | p.Thr652Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4245195 | p.Ile655Val | missense_variant | 1.0 | ethambutol | |
| embA | 4245200 | c.1968C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245206 | c.1974A>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245207 | c.1975T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245215 | c.1983A>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245224 | c.1992T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245257 | c.2025A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245263 | c.2031A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4245281 | c.2049C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245282 | p.Ile684Val | missense_variant | 1.0 | ethambutol | |
| embA | 4245285 | c.2053T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245293 | c.2061T>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245296 | c.2064G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245299 | c.2067A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245326 | c.2094C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245327 | p.Ala699Leu | missense_variant | 1.0 | ethambutol | |
| embA | 4245345 | p.Met705Leu | missense_variant | 1.0 | ethambutol | |
| embA | 4245355 | p.Ala708Gly | missense_variant | 1.0 | ethambutol | |
| embA | 4245497 | c.2265C>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245501 | p.Ala757Thr | missense_variant | 1.0 | ethambutol | |
| embA | 4245512 | c.2280G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4245521 | c.-993G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245524 | c.2292G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4245530 | c.-984T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245531 | p.Ile767Val | missense_variant | 1.0 | ethambutol | |
| embA | 4245535 | p.Ser768Asn | missense_variant | 1.0 | ethambutol | |
| embB | 4245539 | c.-975C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245566 | c.2334C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4245575 | c.-939C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245577 | p.Lys782Arg | missense_variant | 1.0 | ethambutol | |
| embB | 4245594 | c.-920_-919delTCinsAG | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245605 | c.-909G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245606 | p.Leu792Val | missense_variant | 1.0 | ethambutol | |
| embB | 4245620 | c.-894T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245623 | c.2391G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4245662 | c.-852G>C | upstream_gene_variant | 0.98 | ethambutol | |
| embA | 4245674 | c.2442A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4245677 | c.-837G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245693 | p.Ile821Val | missense_variant | 0.98 | ethambutol | |
| embB | 4245701 | c.-813G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245704 | c.-810G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245713 | c.-801G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245714 | c.-800C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245725 | c.-789A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245726 | c.-788T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245731 | c.-783C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245734 | c.-780G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245737 | c.-777A>T | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245740 | c.-774T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245764 | c.-750G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245772 | p.Asn847Thr | missense_variant | 1.0 | ethambutol | |
| embA | 4245785 | c.2553G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247608 | c.1095G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247626 | c.1113C>A | synonymous_variant | 0.95 | ethambutol | |
| embB | 4247629 | c.1116C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247630 | c.1117_1119delCTCinsTTG | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247646 | p.Glu378Ala | missense_variant | 1.0 | ethambutol | Not assoc w R |
| embB | 4247671 | c.1158G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247677 | c.1164C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247684 | c.1171T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247725 | c.1212G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247728 | c.1215G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247734 | c.1221C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247743 | c.1230C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248316 | c.1803C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248319 | c.1806A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248334 | c.1821C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248358 | c.1845C>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248360 | p.Pro616Arg | missense_variant | 1.0 | ethambutol | |
| embB | 4248362 | p.Ser617Glu | missense_variant | 1.0 | ethambutol | |
| embB | 4248407 | p.Leu632Val | missense_variant | 1.0 | ethambutol | |
| embB | 4248410 | p.Phe633Leu | missense_variant | 1.0 | ethambutol | |
| embB | 4248416 | p.Leu635Met | missense_variant | 1.0 | ethambutol | |
| embB | 4248430 | c.1917T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248460 | c.1947C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248469 | c.1956C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248472 | c.1959T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248487 | c.1974C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248504 | p.Asp664Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248508 | c.1995G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248514 | c.2001A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248535 | c.2022C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248541 | c.2028T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248552 | c.2040_2041delCG | frameshift_variant | 1.0 | ethambutol | |
| embB | 4248556 | c.2044_2045insGT | frameshift_variant | 1.0 | ethambutol | |
| embB | 4248569 | c.2056C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248574 | c.2061C>T | synonymous_variant | 1.0 | ethambutol |
