TB-Profiler result

Run: SRR3619841
Summary

Run ID: SRR3619841

Sample name:

Date: 04-04-2023 05:20:53

Number of reads: 1265765

Percentage reads mapped: 44.51

Strain: lineage2.2.1

Drug-resistance: Pre-XDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 1.0
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 1.0
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
gyrA 7570 p.Ala90Val missense_variant 0.74 ofloxacin, moxifloxacin, levofloxacin, fluoroquinolones, ciprofloxacin
rpoB 761155 p.Ser450Leu missense_variant 0.94 rifampicin
rpsL 781687 p.Lys43Arg missense_variant 1.0 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.97 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.89 kanamycin, capreomycin, aminoglycosides, amikacin
katG 2155098 c.1013delG frameshift_variant 0.14 isoniazid
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
pncA 2289207 p.Asp12Gly missense_variant 1.0 pyrazinamide
embB 4247429 p.Met306Val missense_variant 1.0 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6581 p.Thr448Val missense_variant 0.18
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8798 c.1497C>T synonymous_variant 0.12
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575199 c.-149G>T upstream_gene_variant 0.15
mshA 575907 p.Ala187Val missense_variant 1.0
ccsA 620625 p.Ile245Met missense_variant 1.0
rpoB 760916 c.1110C>T synonymous_variant 0.14
rpoB 760920 p.Leu372Met missense_variant 0.12
rpoB 760946 c.1140A>G synonymous_variant 0.17
rpoB 760953 p.Ile383Val missense_variant 0.18
rpoB 760973 c.1167G>C synonymous_variant 0.16
rpoB 760982 c.1176G>C synonymous_variant 0.17
rpoB 760985 c.1179G>C synonymous_variant 0.17
rpoB 760991 c.1185G>C synonymous_variant 0.16
rpoB 760997 c.1191G>C synonymous_variant 0.14
rpoB 761036 c.1230G>C synonymous_variant 0.15
rpoB 761037 c.1231T>C synonymous_variant 0.16
rpoB 762879 p.Met1025Leu missense_variant 0.18
rpoC 762896 c.-474G>C upstream_gene_variant 0.48
rpoC 762917 c.-453C>G upstream_gene_variant 0.62
rpoC 762923 c.-447C>G upstream_gene_variant 0.62
rpoC 762926 c.-444C>G upstream_gene_variant 0.62
rpoC 762929 c.-441G>T upstream_gene_variant 0.62
rpoC 762947 c.-423C>G upstream_gene_variant 0.61
rpoC 762959 c.-411G>C upstream_gene_variant 0.65
rpoC 762962 c.-408C>T upstream_gene_variant 0.66
rpoC 762980 c.-390T>C upstream_gene_variant 0.66
rpoC 762989 c.-381G>C upstream_gene_variant 0.72
rpoC 762995 c.-375G>C upstream_gene_variant 0.74
rpoB 763005 p.Cys1067Val missense_variant 0.7
rpoB 763014 p.Met1070Leu missense_variant 0.68
rpoB 763017 p.Gln1071Glu missense_variant 0.68
rpoC 763028 c.-342T>C upstream_gene_variant 0.7
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763034 c.-336C>G upstream_gene_variant 0.63
rpoB 763038 p.Thr1078Ala missense_variant 0.7
rpoC 763052 c.-318G>C upstream_gene_variant 0.67
rpoC 763053 c.-317T>C upstream_gene_variant 0.77
rpoB 763059 p.Ile1085Val missense_variant 0.72
rpoC 763067 c.-303C>G upstream_gene_variant 0.67
rpoC 763070 c.-300T>C upstream_gene_variant 0.74
rpoB 763075 p.Thr1090Ile missense_variant 0.74
rpoB 763077 p.Val1091Leu missense_variant 0.72
rpoC 763115 c.-255T>C upstream_gene_variant 0.62
rpoC 763133 c.-237G>C upstream_gene_variant 0.46
rpoC 763148 c.-222G>C upstream_gene_variant 0.35
rpoC 763160 c.-210G>C upstream_gene_variant 0.13
rpoB 763161 p.Leu1119Ile missense_variant 0.13
rpoC 763166 c.-204A>G upstream_gene_variant 0.14
rpoC 763169 c.-201A>G upstream_gene_variant 0.13
rpoB 763170 p.Leu1122Met missense_variant 0.13
rpoC 763456 c.87A>G synonymous_variant 0.13
rpoC 763462 c.93G>C synonymous_variant 0.16
rpoC 763468 c.99G>C synonymous_variant 0.24
rpoC 763483 c.114G>C synonymous_variant 0.24
rpoC 763486 c.117T>G synonymous_variant 0.26
rpoC 763492 c.123G>C synonymous_variant 0.29
rpoC 763504 c.135C>T synonymous_variant 0.3
rpoC 763511 p.Cys48Gly missense_variant 0.32
rpoC 763517 p.Lys50Gln missense_variant 0.3
rpoC 763528 c.159G>A synonymous_variant 0.31
rpoC 763531 c.162G>C synonymous_variant 0.29
rpoC 763532 p.Thr55Ser missense_variant 0.29
rpoC 763546 c.177A>G synonymous_variant 0.29
rpoC 763550 p.Tyr61Ala missense_variant 0.29
rpoC 763570 c.201G>C synonymous_variant 0.31
rpoC 763589 p.Ile74Val missense_variant 0.32
rpoC 763609 c.240C>G synonymous_variant 0.35
rpoC 763614 c.246_251delGACCCG disruptive_inframe_deletion 0.34
rpoC 763622 p.Ala85Thr missense_variant 0.36
rpoC 763627 c.258_259insAGCTCC conservative_inframe_insertion 0.35
rpoC 763630 c.261G>C synonymous_variant 0.37
rpoC 763633 c.264T>C synonymous_variant 0.37
rpoC 763636 c.267T>C synonymous_variant 0.38
rpoC 763642 c.273G>C synonymous_variant 0.42
rpoC 763660 c.291T>C synonymous_variant 0.49
rpoC 763675 c.306C>G synonymous_variant 0.5
rpoC 763696 c.327T>C synonymous_variant 0.49
rpoC 763708 c.339G>C synonymous_variant 0.46
rpoC 763714 c.345G>C synonymous_variant 0.39
rpoC 763717 c.348T>C synonymous_variant 0.34
rpoC 763723 c.354G>C synonymous_variant 0.32
rpoC 763727 p.Leu120Met missense_variant 0.33
rpoC 763732 c.363C>G synonymous_variant 0.28
rpoC 763744 c.375G>C synonymous_variant 0.24
rpoC 763751 p.Ile128Val missense_variant 0.17
rpoC 764058 p.Ala230Val missense_variant 1.0
rpoC 764353 c.984G>C synonymous_variant 0.16
rpoC 764371 c.1002G>C synonymous_variant 0.13
rpoC 764485 c.1116G>C synonymous_variant 0.19
rpoC 764497 c.1128A>G synonymous_variant 0.25
rpoC 764498 p.Ser377Ala missense_variant 0.25
rpoC 764503 c.1134G>C synonymous_variant 0.27
rpoC 764521 c.1152T>C synonymous_variant 0.24
rpoC 764533 c.1164C>T synonymous_variant 0.24
rpoC 764536 c.1167G>T synonymous_variant 0.2
rpoC 764545 c.1176C>G synonymous_variant 0.19
rpoC 764548 c.1179G>C synonymous_variant 0.27
rpoC 764549 p.Pro394Thr missense_variant 0.18
rpoC 764560 c.1191T>C synonymous_variant 0.19
rpoC 764561 p.Pro398Ala missense_variant 0.17
rpoC 764566 c.1197C>G synonymous_variant 0.26
rpoC 764572 c.1203G>C synonymous_variant 0.17
rpoC 764575 c.1206T>G synonymous_variant 0.29
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 0.17
rpoC 764581 c.1212T>C synonymous_variant 0.27
rpoC 764582 p.Leu405Met missense_variant 0.27
rpoC 764611 c.1242G>C synonymous_variant 0.47
rpoC 764632 c.1263T>C synonymous_variant 0.56
rpoC 764635 c.1266C>G synonymous_variant 0.55
rpoC 764650 c.1281G>T synonymous_variant 0.59
rpoC 764662 c.1293G>C synonymous_variant 0.62
rpoC 764695 c.1326T>C synonymous_variant 0.68
rpoC 764706 p.Leu446Gln missense_variant 0.61
rpoC 764716 c.1347G>C synonymous_variant 0.61
rpoC 764737 c.1368G>C synonymous_variant 0.51
rpoC 764740 p.Met457Ile missense_variant 0.46
rpoC 764746 c.1377G>C synonymous_variant 0.46
rpoC 764750 p.Val461Ile missense_variant 0.46
rpoC 764759 p.Asn464Gly missense_variant 0.52
rpoC 764764 c.1395T>C synonymous_variant 0.57
rpoC 764765 p.Ala466Ser missense_variant 0.52
rpoC 764780 p.Ser471Ala missense_variant 0.59
rpoC 764792 p.Met475Ala missense_variant 0.55
rpoC 764804 p.Gln479Thr missense_variant 0.57
rpoC 764813 p.Gln482Glu missense_variant 0.55
rpoC 764824 c.1455T>C synonymous_variant 0.55
rpoC 764833 c.1464A>G synonymous_variant 0.55
rpoC 764837 p.Val490Ile missense_variant 0.5
rpoC 764843 p.Ala492Arg missense_variant 0.5
rpoC 764850 p.His494Arg missense_variant 0.52
rpoC 764854 c.1485G>C synonymous_variant 0.52
rpoC 764858 c.1489T>C synonymous_variant 0.48
rpoC 764872 c.1503A>C synonymous_variant 0.42
rpoC 764878 c.1509C>G synonymous_variant 0.36
rpoC 764887 c.1518G>C synonymous_variant 0.24
rpoC 764888 c.1519T>C synonymous_variant 0.24
rpoC 764893 c.1524T>C synonymous_variant 0.23
rpoC 764902 c.1533C>G synonymous_variant 0.2
rpoC 765462 p.Asn698Ser missense_variant 1.0
rpoC 766986 p.Val1206Glu missense_variant 0.2
rpoC 767014 c.3645G>C synonymous_variant 0.44
rpoC 767017 c.3648C>G synonymous_variant 0.44
rpoC 767020 c.3651C>G synonymous_variant 0.47
rpoC 767023 p.Asp1218Glu missense_variant 0.47
rpoC 767038 c.3669G>C synonymous_variant 0.29
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776182 p.Asp767Asn missense_variant 1.0
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
mmpS5 779647 c.-742G>A upstream_gene_variant 0.14
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781751 c.192G>C synonymous_variant 0.18
rpsL 781754 c.195G>C synonymous_variant 0.17
rpsL 781760 c.201T>C synonymous_variant 0.2
rpsL 781794 p.Met79Leu missense_variant 0.3
rpsL 781802 c.243G>C synonymous_variant 0.29
rpsL 781805 c.246G>C synonymous_variant 0.29
rpsL 781811 c.252C>T synonymous_variant 0.3
rpsL 781814 c.255C>T synonymous_variant 0.3
rpsL 781817 c.258G>T synonymous_variant 0.28
rpsL 781829 c.270G>C synonymous_variant 0.26
rpsL 781832 c.273T>C synonymous_variant 0.24
rpsL 781838 c.279G>C synonymous_variant 0.24
rpsL 781851 p.Ile98Val missense_variant 0.15
rpsL 781860 p.Ser101Ala missense_variant 0.16
rpsL 781865 c.306G>C synonymous_variant 0.14
rpsL 781868 c.309T>C synonymous_variant 0.15
rpsL 781871 c.312G>C synonymous_variant 0.15
rpsL 781876 p.Gly106Ala missense_variant 0.15
Rv1258c 1406760 c.580_581insC frameshift_variant 0.93
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471876 n.31G>A non_coding_transcript_exon_variant 0.17
rrs 1471877 n.32A>G non_coding_transcript_exon_variant 0.17
rrs 1471878 n.33C>T non_coding_transcript_exon_variant 0.18
rrs 1471892 n.47G>A non_coding_transcript_exon_variant 0.17
rrs 1471893 n.48T>G non_coding_transcript_exon_variant 0.18
rrs 1471896 n.51T>C non_coding_transcript_exon_variant 0.17
rrs 1472067 n.222G>T non_coding_transcript_exon_variant 0.4
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.4
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.67
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.7
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.89
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.89
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.89
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.84
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.86
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.81
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.89
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.95
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.96
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.91
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.98
rrs 1472284 n.439C>T non_coding_transcript_exon_variant 0.9
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.96
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.96
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.96
rrs 1472293 n.448C>A non_coding_transcript_exon_variant 0.96
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.96
rrs 1472312 n.467_468insA non_coding_transcript_exon_variant 0.96
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.97
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.97
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.97
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.97
rrs 1472333 n.488G>A non_coding_transcript_exon_variant 0.91
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.92
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.98
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.93
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.93
rrs 1472389 n.544G>A non_coding_transcript_exon_variant 0.91
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.96
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.91
rrs 1472434 n.589_590insC non_coding_transcript_exon_variant 0.87
rrs 1472437 n.592T>C non_coding_transcript_exon_variant 0.91
rrs 1472438 n.594delC non_coding_transcript_exon_variant 0.91
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.87
rrs 1472449 n.604C>G non_coding_transcript_exon_variant 0.83
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.87
rrs 1472451 n.606C>A non_coding_transcript_exon_variant 0.86
rrs 1472456 n.611T>C non_coding_transcript_exon_variant 0.87
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 0.87
rrs 1472461 n.616G>T non_coding_transcript_exon_variant 0.86
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.87
rrs 1472463 n.618G>C non_coding_transcript_exon_variant 0.83
rrs 1472467 n.622G>C non_coding_transcript_exon_variant 0.86
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.87
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.83
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.83
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.85
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.91
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.91
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.91
rrs 1472507 n.662C>T non_coding_transcript_exon_variant 0.88
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.94
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.94
rrs 1472571 n.726G>A non_coding_transcript_exon_variant 0.89
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.96
rrs 1472606 n.761C>G non_coding_transcript_exon_variant 0.93
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 0.92
rrs 1472645 n.800G>C non_coding_transcript_exon_variant 0.91
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.97
rrs 1472660 n.815T>A non_coding_transcript_exon_variant 0.95
rrs 1472666 n.821G>T non_coding_transcript_exon_variant 0.92
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.98
rrs 1472674 n.829T>G non_coding_transcript_exon_variant 0.94
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.92
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.98
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.95
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.98
rrs 1472686 n.841G>T non_coding_transcript_exon_variant 0.92
rrs 1472687 n.842A>C non_coding_transcript_exon_variant 0.98
rrs 1472694 n.849C>A non_coding_transcript_exon_variant 0.93
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.98
rrs 1472714 n.869A>T non_coding_transcript_exon_variant 0.96
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.94
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.93
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.96
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.92
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.92
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 0.95
rrs 1472837 n.992C>T non_coding_transcript_exon_variant 0.95
rrs 1472839 n.994_995insG non_coding_transcript_exon_variant 0.94
rrs 1472842 n.997G>A non_coding_transcript_exon_variant 0.89
rrs 1472845 n.1001delC non_coding_transcript_exon_variant 0.94
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.85
rrs 1472854 n.1009G>A non_coding_transcript_exon_variant 0.85
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 0.84
rrs 1472863 n.1018T>A non_coding_transcript_exon_variant 0.84
rrs 1472865 n.1020C>T non_coding_transcript_exon_variant 0.8
rrs 1472868 n.1024delG non_coding_transcript_exon_variant 0.89
rrs 1472878 n.1033G>A non_coding_transcript_exon_variant 0.9
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.91
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.97
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.95
rrs 1472953 n.1109dupT non_coding_transcript_exon_variant 0.96
rrs 1472957 n.1113delA non_coding_transcript_exon_variant 0.97
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.96
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.99
rrs 1472988 n.1143T>G non_coding_transcript_exon_variant 0.96
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.99
rrs 1472993 n.1148G>T non_coding_transcript_exon_variant 0.96
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 1.0
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 1.0
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 1.0
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 1.0
rrs 1473097 n.1252G>A non_coding_transcript_exon_variant 0.96
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 1.0
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.98
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.99
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.99
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.99
rrs 1473134 n.1289T>C non_coding_transcript_exon_variant 0.93
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.98
rrs 1473147 n.1302G>A non_coding_transcript_exon_variant 0.92
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.93
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.97
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.91
rrs 1473269 n.1424C>T non_coding_transcript_exon_variant 0.9
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.92
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.88
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.89
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.91
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.89
rrs 1473320 n.1475G>A non_coding_transcript_exon_variant 0.84
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 0.84
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.67
rrl 1473746 n.89T>A non_coding_transcript_exon_variant 0.67
rrl 1473747 n.90C>T non_coding_transcript_exon_variant 0.67
rrl 1473750 n.93C>G non_coding_transcript_exon_variant 0.67
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.67
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.67
rrl 1473765 n.108A>T non_coding_transcript_exon_variant 0.5
rrl 1473828 n.173_174delTG non_coding_transcript_exon_variant 0.33
rrl 1473834 n.178_179insTAG non_coding_transcript_exon_variant 0.33
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.5
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 0.5
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.5
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.5
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 0.5
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.5
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.44
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.44
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.67
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.5
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.33
rrl 1474153 n.496C>T non_coding_transcript_exon_variant 0.33
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 0.33
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.6
rrl 1474166 n.509G>A non_coding_transcript_exon_variant 0.6
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.88
rrl 1474184 n.527C>A non_coding_transcript_exon_variant 0.88
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.92
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.89
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.89
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.92
rrl 1474265 n.608G>T non_coding_transcript_exon_variant 0.9
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.89
rrl 1474275 n.618T>A non_coding_transcript_exon_variant 0.88
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.91
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.95
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 1.0
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 1.0
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 1.0
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 1.0
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 1.0
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 1.0
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.96
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 1.0
rrl 1474414 n.757C>T non_coding_transcript_exon_variant 1.0
rrl 1474415 n.758C>T non_coding_transcript_exon_variant 1.0
rrl 1474416 n.761_784delCACGCGCATACGCGCGTGTGAATA non_coding_transcript_exon_variant 1.0
rrl 1474444 n.787G>C non_coding_transcript_exon_variant 1.0
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 1.0
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 1.0
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 1.0
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 1.0
rrl 1474488 n.831G>C non_coding_transcript_exon_variant 1.0
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 1.0
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 1.0
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 1.0
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 1.0
rrl 1474516 n.859C>G non_coding_transcript_exon_variant 1.0
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.95
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.96
rrl 1474601 n.944C>T non_coding_transcript_exon_variant 0.96
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.99
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.96
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.97
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.97
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.97
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.45
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.98
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 0.99
rrl 1474717 n.1060_1061insGTGAG non_coding_transcript_exon_variant 0.99
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.92
rrl 1474723 n.1066G>A non_coding_transcript_exon_variant 0.92
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.98
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.9
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.89
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.89
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.98
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.98
rrl 1474770 n.1113G>A non_coding_transcript_exon_variant 0.91
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.99
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.92
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 0.99
rrl 1474794 n.1137C>A non_coding_transcript_exon_variant 0.99
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.99
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.99
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.94
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.99
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.97
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.97
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.97
rrl 1474920 n.1263G>A non_coding_transcript_exon_variant 0.95
rrl 1474938 n.1281G>A non_coding_transcript_exon_variant 0.8
rrl 1474945 n.1288C>T non_coding_transcript_exon_variant 0.67
rrl 1474946 n.1289C>T non_coding_transcript_exon_variant 0.67
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.62
rrl 1475108 n.1451C>T non_coding_transcript_exon_variant 0.62
rrl 1475111 n.1454G>A non_coding_transcript_exon_variant 0.62
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.62
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.62
rrl 1475119 n.1462C>T non_coding_transcript_exon_variant 0.71
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.71
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.75
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.82
rrl 1475488 n.1831G>C non_coding_transcript_exon_variant 0.67
rrl 1475508 n.1851A>T non_coding_transcript_exon_variant 0.88
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0
rrl 1475536 n.1879C>A non_coding_transcript_exon_variant 1.0
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 1.0
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 1.0
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 1.0
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 1.0
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 1.0
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 1.0
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.91
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.92
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.93
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.95
rrl 1475692 n.2035G>C non_coding_transcript_exon_variant 0.95
rrl 1475735 n.2078T>C non_coding_transcript_exon_variant 0.92
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.97
rrl 1475776 n.2119G>C non_coding_transcript_exon_variant 0.92
rrl 1475777 n.2120A>C non_coding_transcript_exon_variant 0.92
rrl 1475791 n.2134A>G non_coding_transcript_exon_variant 0.92
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.88
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.92
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.92
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.92
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.89
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.92
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.93
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.9
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.9
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.93
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.92
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.96
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.87
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.9
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 0.72
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.75
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.75
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.7
rrl 1476047 n.2390G>C non_coding_transcript_exon_variant 0.74
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.82
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.88
rrl 1476079 n.2422G>A non_coding_transcript_exon_variant 0.84
rrl 1476080 n.2423T>C non_coding_transcript_exon_variant 0.84
rrl 1476081 n.2424A>T non_coding_transcript_exon_variant 0.88
rrl 1476082 n.2425T>C non_coding_transcript_exon_variant 0.88
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.88
rrl 1476087 n.2430C>T non_coding_transcript_exon_variant 0.89
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.88
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.92
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.92
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.93
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.91
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.93
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.9
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.92
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.94
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.98
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.98
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.99
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.95
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.97
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.97
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.97
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.97
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.97
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.97
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.95
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.94
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.94
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.97
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.96
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.97
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.92
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.9
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.9
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.91
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.84
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.9
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.85
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.82
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.82
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.74
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.74
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.82
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.82
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.74
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.81
rrl 1476544 n.2887T>A non_coding_transcript_exon_variant 0.85
rrl 1476566 n.2909A>T non_coding_transcript_exon_variant 0.84
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.84
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.79
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.79
rrl 1476586 n.2929C>A non_coding_transcript_exon_variant 0.77
rrl 1476596 n.2939C>T non_coding_transcript_exon_variant 0.73
rrl 1476601 n.2944G>A non_coding_transcript_exon_variant 0.72
rrl 1476613 n.2956G>T non_coding_transcript_exon_variant 0.53
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.53
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.56
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.56
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.56
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.56
rrl 1476630 n.2973A>T non_coding_transcript_exon_variant 0.56
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.23
fabG1 1673641 p.Val68Leu missense_variant 0.17
inhA 1674653 p.Pro151Gln missense_variant 0.12
rpsA 1833661 c.120A>G synonymous_variant 0.33
rpsA 1833665 p.Thr42Pro missense_variant 0.12
rpsA 1833676 c.135A>G synonymous_variant 0.29
rpsA 1833679 c.138G>C synonymous_variant 0.18
rpsA 1833685 c.144G>C synonymous_variant 0.29
rpsA 1833694 c.153G>T synonymous_variant 0.18
rpsA 1833697 c.156C>G synonymous_variant 0.29
rpsA 1833704 p.Ile55Val missense_variant 0.18
rpsA 1833707 p.Gly56Ser missense_variant 0.18
rpsA 1833711 p.Tyr57Phe missense_variant 0.17
rpsA 1833721 c.180A>G synonymous_variant 0.26
rpsA 1833727 c.186G>C synonymous_variant 0.26
rpsA 1833734 p.Ala65Ser missense_variant 0.32
rpsA 1833742 c.201A>G synonymous_variant 0.32
rpsA 1833745 c.204G>C synonymous_variant 0.21
rpsA 1833781 c.240T>C synonymous_variant 0.27
rpsA 1833782 c.241_242delTCinsAG synonymous_variant 0.2
rpsA 1833790 c.249T>C synonymous_variant 0.18
rpsA 1833795 p.Glu85Val missense_variant 0.22
rpsA 1833802 c.261A>G synonymous_variant 0.26
rpsA 1833805 c.264C>G synonymous_variant 0.21
rpsA 1833808 c.267G>T synonymous_variant 0.22
rpsA 1833811 c.270G>T synonymous_variant 0.22
rpsA 1833815 p.Thr92Gln missense_variant 0.28
rpsA 1833829 c.288A>G synonymous_variant 0.33
rpsA 1833832 c.291G>A synonymous_variant 0.29
rpsA 1833838 c.297G>T synonymous_variant 0.4
rpsA 1833841 c.300C>G synonymous_variant 0.31
rpsA 1833847 c.306C>G synonymous_variant 0.38
rpsA 1833850 c.309C>G synonymous_variant 0.31
rpsA 1833856 c.315A>G synonymous_variant 0.35
rpsA 1833874 c.333T>C synonymous_variant 0.25
rpsA 1833884 p.Thr115Asp missense_variant 0.29
rpsA 1833887 p.Ile116Val missense_variant 0.29
rpsA 1833893 p.Ala118Lys missense_variant 0.29
rpsA 1833896 p.Leu119Ile missense_variant 0.29
rpsA 1833907 p.Lys122Asn missense_variant 0.27
rpsA 1833912 p.Glu124Gly missense_variant 0.27
rpsA 1833915 p.Ala125Val missense_variant 0.25
rpsA 1833921 p.Lys127Thr missense_variant 0.24
rpsA 1833928 c.387G>C synonymous_variant 0.24
rpsA 1833949 c.408T>C synonymous_variant 0.25
rpsA 1833955 c.414G>C synonymous_variant 0.25
rpsA 1833959 p.Leu140Val missense_variant 0.31
rpsA 1833970 c.429G>C synonymous_variant 0.29
rpsA 1833979 c.438T>C synonymous_variant 0.19
rpsA 1833988 c.447C>G synonymous_variant 0.12
rpsA 1833997 c.456G>C synonymous_variant 0.18
rpsA 1834000 c.459G>C synonymous_variant 0.12
rpsA 1834012 c.471G>C synonymous_variant 0.13
rpsA 1834015 c.474G>C synonymous_variant 0.13
rpsA 1834024 c.483G>C synonymous_variant 0.13
rpsA 1834030 c.489C>G synonymous_variant 0.12
rpsA 1834177 c.636A>C synonymous_variant 1.0
rpsA 1834222 c.681T>C synonymous_variant 0.12
rpsA 1834231 c.690T>C synonymous_variant 0.14
rpsA 1834239 c.699T>C synonymous_variant 0.17
rpsA 1834243 c.702G>C synonymous_variant 0.15
rpsA 1834249 c.708T>C synonymous_variant 0.15
rpsA 1834255 c.714C>G synonymous_variant 0.24
rpsA 1834261 c.720A>G synonymous_variant 0.24
rpsA 1834279 p.Asp246Glu missense_variant 0.26
rpsA 1834283 p.Pro248Ala missense_variant 0.27
rpsA 1834288 c.747C>G synonymous_variant 0.27
rpsA 1834294 c.753G>C synonymous_variant 0.3
rpsA 1834298 p.Gln253Glu missense_variant 0.3
rpsA 1834303 c.762T>G synonymous_variant 0.32
rpsA 1834306 c.765T>C synonymous_variant 0.32
rpsA 1834307 p.Asp256Gln missense_variant 0.32
rpsA 1834325 p.Val262Ile missense_variant 0.35
rpsA 1834333 p.Asp264Glu missense_variant 0.35
rpsA 1834340 p.Met267Leu missense_variant 0.38
rpsA 1834348 c.807T>C synonymous_variant 0.38
rpsA 1834354 c.813G>C synonymous_variant 0.38
rpsA 1834357 c.816T>C synonymous_variant 0.38
rpsA 1834361 c.820T>C synonymous_variant 0.38
rpsA 1834366 c.825A>G synonymous_variant 0.43
rpsA 1834378 c.837T>G synonymous_variant 0.44
rpsA 1834384 c.843A>G synonymous_variant 0.42
rpsA 1834395 p.Arg285Gln missense_variant 0.44
rpsA 1834397 p.His286Val missense_variant 0.44
rpsA 1834411 c.870T>C synonymous_variant 0.47
rpsA 1834423 c.882G>C synonymous_variant 0.44
rpsA 1834430 p.Val297Thr missense_variant 0.47
rpsA 1834451 c.910_912delTTGinsCTC synonymous_variant 0.44
rpsA 1834468 c.927A>G synonymous_variant 0.38
rpsA 1834482 p.Glu314Ala missense_variant 0.23
rpsA 1834486 p.Glu315Asp missense_variant 0.23
rpsA 1834489 c.948T>C synonymous_variant 0.27
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168988 p.Thr542Ile missense_variant 0.15
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289872 c.-632dupC upstream_gene_variant 0.12
folC 2747437 p.Met54Ile missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612428 p.Ala230Glu missense_variant 0.11
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
Rv3236c 3612821 p.Leu99Pro missense_variant 0.14
clpC1 4038767 c.1938G>T synonymous_variant 0.15
clpC1 4038836 c.1869G>C synonymous_variant 0.16
clpC1 4038860 c.1845G>C synonymous_variant 0.2
clpC1 4038881 c.1824C>G synonymous_variant 0.15
clpC1 4039670 p.Val345Ile missense_variant 0.2
clpC1 4039691 c.1014G>C synonymous_variant 0.33
clpC1 4039711 p.Ile332Phe missense_variant 0.38
clpC1 4039714 p.Tyr331His missense_variant 0.4
clpC1 4039724 c.981A>G synonymous_variant 0.41
clpC1 4039736 c.969C>G synonymous_variant 0.38
clpC1 4039751 c.954A>G synonymous_variant 0.34
clpC1 4039757 c.948A>G synonymous_variant 0.32
clpC1 4039760 c.945T>C synonymous_variant 0.32
clpC1 4039766 c.939T>C synonymous_variant 0.32
clpC1 4039773 p.Lys311Leu missense_variant 0.27
clpC1 4039778 c.927A>G synonymous_variant 0.26
clpC1 4039793 c.912C>G synonymous_variant 0.25
clpC1 4039811 c.894C>G synonymous_variant 0.32
clpC1 4039817 c.888A>C synonymous_variant 0.35
clpC1 4039820 c.885T>C synonymous_variant 0.36
clpC1 4039826 c.879C>G synonymous_variant 0.33
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.33
clpC1 4039838 p.Leu289Ile missense_variant 0.43
clpC1 4039850 c.855T>C synonymous_variant 0.45
clpC1 4039853 p.Leu284Val missense_variant 0.45
clpC1 4039865 c.840T>C synonymous_variant 0.48
clpC1 4039875 p.Asn277Arg missense_variant 0.46
clpC1 4039887 p.Leu273Thr missense_variant 0.54
clpC1 4039898 c.807C>G synonymous_variant 0.63
clpC1 4039904 c.801A>G synonymous_variant 0.68
clpC1 4039916 c.789T>C synonymous_variant 0.58
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.53
clpC1 4039931 c.774T>A synonymous_variant 0.5
clpC1 4039934 c.771G>C synonymous_variant 0.42
clpC1 4039937 p.Val256Ile missense_variant 0.46
clpC1 4039952 c.753T>C synonymous_variant 0.54
clpC1 4039955 c.750G>C synonymous_variant 0.52
clpC1 4039960 p.Thr249Ser missense_variant 0.55
clpC1 4039964 c.741C>G synonymous_variant 0.54
clpC1 4039979 c.726C>G synonymous_variant 0.56
clpC1 4040000 p.His235Lys missense_variant 0.56
clpC1 4040003 c.702G>C synonymous_variant 0.56
clpC1 4040009 c.696C>G synonymous_variant 0.56
clpC1 4040018 c.687G>C synonymous_variant 0.56
clpC1 4040021 c.684A>C synonymous_variant 0.59
clpC1 4040024 c.681A>G synonymous_variant 0.63
clpC1 4040033 c.672G>C synonymous_variant 0.59
clpC1 4040069 c.636G>C synonymous_variant 0.46
clpC1 4040083 p.Thr208Ser missense_variant 0.31
clpC1 4040087 c.618G>C synonymous_variant 0.3
clpC1 4040090 c.615T>G synonymous_variant 0.3
clpC1 4040096 p.Val203Ile missense_variant 0.2
clpC1 4040105 c.600C>G synonymous_variant 0.18
clpC1 4040108 c.597G>C synonymous_variant 0.18
clpC1 4040117 c.588A>G synonymous_variant 0.22
clpC1 4040129 c.576C>G synonymous_variant 0.2
embC 4241958 p.Arg699Leu missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
aftB 4267647 p.Asp397Gly missense_variant 1.0
ethA 4326735 p.Ala247Ser missense_variant 0.18
whiB6 4338425 p.Val33Ile missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 0.94
gid 4407927 p.Glu92Asp missense_variant 1.0