TB-Profiler result

Run: SRR21469201
Summary

Run ID: SRR21469201

Sample name:

Date: 04-04-2023 02:06:13

Number of reads: 1209858

Percentage reads mapped: 43.18

Strain: La1.7.1

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
La1 M.bovis None None 1.0
La1.7 M.bovis None None 1.0
La1.7.1 M.bovis None None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.62 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.49 kanamycin, capreomycin, aminoglycosides, amikacin
pncA 2289073 p.His57Asp missense_variant 1.0 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5752 c.513G>A synonymous_variant 1.0
gyrA 6406 c.-896C>T upstream_gene_variant 1.0
gyrB 6446 p.Ala403Ser missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8285 c.984C>T synonymous_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9217 p.Asp639Ala missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
ccsA 619706 c.-185G>A upstream_gene_variant 1.0
rpoC 762863 c.-507T>C upstream_gene_variant 0.12
rpoB 762879 p.Met1025Leu missense_variant 0.19
rpoC 762899 c.-471G>C upstream_gene_variant 0.31
rpoC 762917 c.-453C>A upstream_gene_variant 0.36
rpoC 762920 c.-450C>T upstream_gene_variant 0.36
rpoC 762926 c.-444C>G upstream_gene_variant 0.36
rpoC 762929 c.-441G>T upstream_gene_variant 0.36
rpoC 762932 c.-438G>C upstream_gene_variant 0.36
rpoC 762959 c.-411G>C upstream_gene_variant 0.4
rpoC 762962 c.-408C>T upstream_gene_variant 0.4
rpoC 762983 c.-387C>A upstream_gene_variant 0.41
rpoC 762989 c.-381G>C upstream_gene_variant 0.39
rpoC 762995 c.-375G>T upstream_gene_variant 0.38
rpoB 763005 p.Cys1067Val missense_variant 0.39
rpoB 763014 p.Met1070Leu missense_variant 0.38
rpoB 763017 p.Gln1071Glu missense_variant 0.38
rpoC 763028 c.-342T>C upstream_gene_variant 0.35
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763034 c.-336C>G upstream_gene_variant 0.34
rpoB 763038 p.Thr1078Ala missense_variant 0.33
rpoC 763043 c.-327G>C upstream_gene_variant 0.34
rpoC 763052 c.-318G>C upstream_gene_variant 0.37
rpoC 763053 c.-317_-315delTTGinsCTC upstream_gene_variant 0.37
rpoC 763058 c.-312C>G upstream_gene_variant 0.36
rpoC 763070 c.-300T>C upstream_gene_variant 0.38
rpoB 763075 p.Thr1090Ile missense_variant 0.36
rpoB 763077 p.Val1091Leu missense_variant 0.36
rpoC 763115 c.-255T>C upstream_gene_variant 0.29
rpoB 763126 p.Pro1107Gln missense_variant 0.26
rpoC 763456 c.87A>G synonymous_variant 0.16
rpoC 763462 c.93G>C synonymous_variant 0.16
rpoC 763465 c.96G>A synonymous_variant 0.16
rpoC 763468 c.99G>C synonymous_variant 0.18
rpoC 763483 c.114G>C synonymous_variant 0.21
rpoC 763486 c.117T>C synonymous_variant 0.21
rpoC 763504 c.135C>T synonymous_variant 0.27
rpoC 763507 c.138G>C synonymous_variant 0.26
rpoC 763511 p.Cys48Gly missense_variant 0.27
rpoC 763517 p.Lys50Gln missense_variant 0.29
rpoC 763528 c.159G>C synonymous_variant 0.31
rpoC 763532 p.Thr55Ser missense_variant 0.32
rpoC 763546 c.177A>G synonymous_variant 0.34
rpoC 763550 p.Tyr61Ala missense_variant 0.33
rpoC 763570 c.201G>C synonymous_variant 0.38
rpoC 763573 c.204G>C synonymous_variant 0.39
rpoC 763589 p.Ile74Val missense_variant 0.39
rpoC 763609 c.240C>G synonymous_variant 0.42
rpoC 763614 c.246_251delGACCCG disruptive_inframe_deletion 0.43
rpoC 763622 p.Ala85Thr missense_variant 0.41
rpoC 763627 c.258_259insAGCTCC conservative_inframe_insertion 0.41
rpoC 763630 c.261G>C synonymous_variant 0.41
rpoC 763642 c.273G>C synonymous_variant 0.4
rpoC 763648 c.279C>T synonymous_variant 0.42
rpoC 763660 c.291T>C synonymous_variant 0.42
rpoC 763666 c.297G>T synonymous_variant 0.42
rpoC 763696 c.327T>C synonymous_variant 0.29
rpoC 763708 c.339G>C synonymous_variant 0.3
rpoC 763714 c.345G>C synonymous_variant 0.28
rpoC 763717 c.348T>C synonymous_variant 0.26
rpoC 763723 c.354G>C synonymous_variant 0.26
rpoC 763727 p.Leu120Met missense_variant 0.26
rpoC 763732 c.363C>A synonymous_variant 0.23
rpoC 763744 c.375G>C synonymous_variant 0.16
rpoC 763751 p.Ile128Val missense_variant 0.12
rpoC 764380 c.1011G>C synonymous_variant 0.12
rpoC 764387 c.1018T>C synonymous_variant 0.14
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.2
rpoC 764428 c.1059G>T synonymous_variant 0.17
rpoC 764431 c.1062G>T synonymous_variant 0.17
rpoC 764432 p.Lys355Arg missense_variant 0.17
rpoC 764435 c.1066_1068delAGGinsCGT synonymous_variant 0.17
rpoC 764446 c.1077T>C synonymous_variant 0.21
rpoC 764449 c.1080G>C synonymous_variant 0.2
rpoC 764455 c.1086G>C synonymous_variant 0.21
rpoC 764458 c.1089G>C synonymous_variant 0.21
rpoC 764461 c.1092A>G synonymous_variant 0.22
rpoC 764485 c.1116G>C synonymous_variant 0.31
rpoC 764497 c.1128A>G synonymous_variant 0.36
rpoC 764498 p.Ser377Ala missense_variant 0.36
rpoC 764509 c.1140G>A synonymous_variant 0.36
rpoC 764521 c.1152T>C synonymous_variant 0.34
rpoC 764524 c.1155C>T synonymous_variant 0.34
rpoC 764530 c.1161C>T synonymous_variant 0.33
rpoC 764533 c.1164C>T synonymous_variant 0.33
rpoC 764536 c.1167G>C synonymous_variant 0.33
rpoC 764548 c.1179G>T synonymous_variant 0.33
rpoC 764549 p.Pro394Thr missense_variant 0.33
rpoC 764561 p.Pro398Ala missense_variant 0.33
rpoC 764566 c.1197C>G synonymous_variant 0.33
rpoC 764575 c.1206T>C synonymous_variant 0.33
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 0.33
rpoC 764581 c.1212T>C synonymous_variant 0.34
rpoC 764582 p.Leu405Met missense_variant 0.34
rpoC 764587 c.1218C>G synonymous_variant 0.33
rpoC 764593 c.1224C>T synonymous_variant 0.33
rpoC 764602 c.1233C>T synonymous_variant 0.32
rpoC 764605 c.1236G>T synonymous_variant 0.3
rpoC 764611 c.1242G>T synonymous_variant 0.31
rpoC 764626 c.1257C>A synonymous_variant 0.28
rpoC 764644 c.1275G>C synonymous_variant 0.24
rpoC 764650 c.1281G>T synonymous_variant 0.24
rpoC 764660 p.Val431Ile missense_variant 0.23
rpoC 764706 p.Leu446Gln missense_variant 0.17
rpoC 764713 c.1344G>T synonymous_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0
fbiC 1305494 c.2565_*55delGGCCTAGCCCCGGCGACGATGCCGGGTCGCGGGATGCGGCCCGTTGAGGAGCGGGGCAATCT frameshift_variant&stop_lost&splice_region_variant 0.21
Rv1258c 1406161 p.Ala394Thr missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.13
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.13
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.16
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.26
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.43
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.42
rrs 1472256 n.411T>C non_coding_transcript_exon_variant 0.41
rrs 1472284 n.439C>T non_coding_transcript_exon_variant 0.32
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.32
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.32
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.32
rrs 1472293 n.448C>A non_coding_transcript_exon_variant 0.32
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.32
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.32
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.33
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.34
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.35
rrs 1472333 n.488G>A non_coding_transcript_exon_variant 0.4
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.43
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.47
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.58
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.55
rrs 1472389 n.544G>A non_coding_transcript_exon_variant 0.55
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.56
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.44
rrs 1472434 n.589_590insC non_coding_transcript_exon_variant 0.34
rrs 1472437 n.592T>C non_coding_transcript_exon_variant 0.35
rrs 1472438 n.594delC non_coding_transcript_exon_variant 0.35
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.34
rrs 1472449 n.604C>G non_coding_transcript_exon_variant 0.34
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.34
rrs 1472451 n.606C>A non_coding_transcript_exon_variant 0.34
rrs 1472456 n.611T>C non_coding_transcript_exon_variant 0.33
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 0.34
rrs 1472461 n.616G>T non_coding_transcript_exon_variant 0.34
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.36
rrs 1472463 n.618G>C non_coding_transcript_exon_variant 0.36
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.36
rrs 1472467 n.622G>C non_coding_transcript_exon_variant 0.36
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.36
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.36
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.36
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.4
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.55
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.54
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.55
rrs 1472507 n.662C>T non_coding_transcript_exon_variant 0.6
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.66
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.67
rrs 1472571 n.726G>A non_coding_transcript_exon_variant 0.68
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.68
rrs 1472606 n.761C>G non_coding_transcript_exon_variant 0.67
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.67
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 0.67
rrs 1472645 n.800G>C non_coding_transcript_exon_variant 0.64
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.63
rrs 1472660 n.815T>A non_coding_transcript_exon_variant 0.66
rrs 1472666 n.821G>T non_coding_transcript_exon_variant 0.66
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.69
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.7
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.69
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.68
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.68
rrs 1472686 n.841G>A non_coding_transcript_exon_variant 0.67
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.67
rrs 1472694 n.849C>A non_coding_transcript_exon_variant 0.67
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.67
rrs 1472714 n.869A>T non_coding_transcript_exon_variant 0.67
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.57
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.52
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.17
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.37
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.58
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.57
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.58
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.58
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.6
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.62
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.62
rrs 1472993 n.1148G>T non_coding_transcript_exon_variant 0.61
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.68
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.72
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.72
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.73
rrs 1473097 n.1252G>A non_coding_transcript_exon_variant 0.75
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.75
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.75
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.75
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.74
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.74
rrs 1473134 n.1289T>C non_coding_transcript_exon_variant 0.77
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.75
rrs 1473147 n.1302G>A non_coding_transcript_exon_variant 0.74
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.73
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.73
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.66
rrs 1473269 n.1424C>T non_coding_transcript_exon_variant 0.61
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.59
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.56
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.59
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.58
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.48
rrs 1473320 n.1475G>A non_coding_transcript_exon_variant 0.48
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 0.49
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.16
rrl 1474141 n.484G>C non_coding_transcript_exon_variant 0.18
rrl 1474142 n.485C>G non_coding_transcript_exon_variant 0.18
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.23
rrl 1474153 n.496C>T non_coding_transcript_exon_variant 0.23
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 0.27
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.35
rrl 1474166 n.509G>A non_coding_transcript_exon_variant 0.35
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.5
rrl 1474184 n.527C>A non_coding_transcript_exon_variant 0.5
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.48
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.48
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.48
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.47
rrl 1474265 n.608G>T non_coding_transcript_exon_variant 0.44
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.43
rrl 1474275 n.618T>A non_coding_transcript_exon_variant 0.43
rrl 1474280 n.623C>T non_coding_transcript_exon_variant 0.43
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.43
rrl 1474291 n.635_645delTTCCTCTCCGG non_coding_transcript_exon_variant 0.41
rrl 1474305 n.648G>T non_coding_transcript_exon_variant 0.38
rrl 1474308 n.653_654delTG non_coding_transcript_exon_variant 0.38
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.38
rrl 1474317 n.660G>A non_coding_transcript_exon_variant 0.38
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.45
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.44
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.45
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.48
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.48
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.42
rrl 1474414 n.757C>T non_coding_transcript_exon_variant 0.3
rrl 1474415 n.758C>T non_coding_transcript_exon_variant 0.27
rrl 1474416 n.761_784delCACGCGCATACGCGCGTGTGAATA non_coding_transcript_exon_variant 0.3
rrl 1474444 n.787G>C non_coding_transcript_exon_variant 0.28
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 0.29
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 0.38
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.39
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.5
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.59
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.64
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.67
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.68
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.66
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.7
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.68
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.68
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.67
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.65
rrl 1474601 n.944C>T non_coding_transcript_exon_variant 0.64
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.54
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.51
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.5
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.5
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.51
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.68
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 0.64
rrl 1474717 n.1060_1061insGTGAG non_coding_transcript_exon_variant 0.67
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.7
rrl 1474723 n.1066G>A non_coding_transcript_exon_variant 0.69
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.68
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.7
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.68
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.69
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.69
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.71
rrl 1474770 n.1113G>A non_coding_transcript_exon_variant 0.71
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.71
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.71
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.71
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.71
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 0.7
rrl 1474794 n.1137C>A non_coding_transcript_exon_variant 0.7
rrl 1474800 n.1143T>C non_coding_transcript_exon_variant 0.7
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.69
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.65
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.66
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.66
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.66
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.5
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.5
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.49
rrl 1474920 n.1263G>A non_coding_transcript_exon_variant 0.46
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.12
rrl 1475652 n.1995C>T non_coding_transcript_exon_variant 0.13
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.13
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.12
rrl 1475692 n.2035G>C non_coding_transcript_exon_variant 0.53
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.75
rrl 1475764 n.2107A>G non_coding_transcript_exon_variant 0.74
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.74
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.75
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.7
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.7
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.7
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.7
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.73
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.7
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.71
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.69
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.72
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.7
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.72
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.74
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.74
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.75
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 0.73
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.73
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.73
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.73
rrl 1476040 n.2383C>T non_coding_transcript_exon_variant 0.73
rrl 1476045 n.2388G>C non_coding_transcript_exon_variant 0.73
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.73
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.73
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 0.73
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.69
rrl 1476079 n.2422G>A non_coding_transcript_exon_variant 0.65
rrl 1476080 n.2423T>C non_coding_transcript_exon_variant 0.65
rrl 1476081 n.2424A>T non_coding_transcript_exon_variant 0.65
rrl 1476082 n.2425T>C non_coding_transcript_exon_variant 0.64
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.65
rrl 1476087 n.2430C>T non_coding_transcript_exon_variant 0.65
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.66
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.67
rrl 1476104 n.2448delG non_coding_transcript_exon_variant 0.67
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.68
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.69
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.71
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.74
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.73
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.7
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.7
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.72
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.73
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.75
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.77
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.74
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.76
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.76
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.77
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.77
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.77
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.77
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.77
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.77
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.78
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.79
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.8
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.8
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.78
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.76
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.73
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.66
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.57
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.55
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.56
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.55
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.56
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.56
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.56
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.55
rrl 1476544 n.2887T>A non_coding_transcript_exon_variant 0.54
rrl 1476566 n.2909A>T non_coding_transcript_exon_variant 0.48
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.47
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.35
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.36
rrl 1476586 n.2929C>T non_coding_transcript_exon_variant 0.34
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.36
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.33
rrl 1476613 n.2956G>A non_coding_transcript_exon_variant 0.29
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.29
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.28
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.26
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.26
rrl 1476630 n.2973A>T non_coding_transcript_exon_variant 0.26
rpsA 1833832 c.291G>A synonymous_variant 0.14
rpsA 1833838 c.297G>T synonymous_variant 0.17
rpsA 1833841 c.300C>G synonymous_variant 0.2
rpsA 1833856 c.315A>G synonymous_variant 0.2
rpsA 1833862 c.321G>A synonymous_variant 0.2
rpsA 1833883 c.342C>A synonymous_variant 0.15
rpsA 1833884 p.Thr115Asp missense_variant 0.15
rpsA 1833887 p.Ile116Val missense_variant 0.15
rpsA 1833893 p.Ala118Lys missense_variant 0.16
rpsA 1833896 p.Leu119Ile missense_variant 0.16
rpsA 1833907 p.Lys122Asn missense_variant 0.17
rpsA 1833912 p.Glu124Gly missense_variant 0.17
rpsA 1833915 p.Ala125Val missense_variant 0.17
rpsA 1833921 p.Lys127Thr missense_variant 0.16
rpsA 1833925 c.384C>T synonymous_variant 0.16
rpsA 1833952 c.411C>A synonymous_variant 0.2
rpsA 1833955 c.414G>C synonymous_variant 0.2
rpsA 1833959 p.Leu140Val missense_variant 0.2
rpsA 1833970 c.429G>A synonymous_variant 0.2
rpsA 1833973 c.432G>C synonymous_variant 0.2
rpsA 1833979 c.438T>C synonymous_variant 0.19
rpsA 1833988 c.447C>G synonymous_variant 0.2
rpsA 1833997 c.456G>C synonymous_variant 0.19
rpsA 1833998 p.Val153Ile missense_variant 0.19
rpsA 1834004 p.Met155Leu missense_variant 0.17
rpsA 1834012 c.471G>C synonymous_variant 0.18
rpsA 1834015 c.474G>C synonymous_variant 0.17
rpsA 1834024 c.483G>C synonymous_variant 0.17
rpsA 1834025 p.Gln162Thr missense_variant 0.16
rpsA 1834030 c.489C>G synonymous_variant 0.16
rpsA 1834034 p.Ile165Leu missense_variant 0.16
rpsA 1834040 p.Lys167Gln missense_variant 0.17
rpsA 1834061 p.Ile174Leu missense_variant 0.17
rpsA 1834069 c.528G>C synonymous_variant 0.15
rpsA 1834859 p.Ala440Thr missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2103092 c.-50T>C upstream_gene_variant 1.0
ndh 2103173 c.-132delG upstream_gene_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155503 c.609C>T synonymous_variant 1.0
katG 2156025 c.87C>A synonymous_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168011 p.Ser868Arg missense_variant 1.0
PPE35 2168319 p.Thr765Ile missense_variant 1.0
PPE35 2168814 c.1798dupA frameshift_variant 1.0
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
ald 3086728 c.-92C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087084 c.266delA frameshift_variant 1.0
Rv3083 3448783 p.Val94Ile missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474427 p.Val141Ile missense_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
fbiB 3642478 p.Asp315Ala missense_variant 1.0
rpoA 3878630 c.-124delC upstream_gene_variant 1.0
clpC1 4038403 c.2302T>C synonymous_variant 1.0
clpC1 4039610 c.1095G>C synonymous_variant 0.12
clpC1 4039691 c.1014G>C synonymous_variant 0.14
clpC1 4039711 p.Ile332Phe missense_variant 0.16
clpC1 4039714 p.Tyr331His missense_variant 0.17
clpC1 4039724 c.981A>G synonymous_variant 0.16
clpC1 4039742 c.963C>T synonymous_variant 0.12
clpC1 4039751 c.954A>G synonymous_variant 0.13
clpC1 4039757 c.948A>G synonymous_variant 0.13
clpC1 4039760 c.945T>C synonymous_variant 0.13
clpC1 4039766 c.939T>C synonymous_variant 0.13
clpC1 4039772 p.Lys311Leu missense_variant 0.12
clpC1 4039775 c.930G>T synonymous_variant 0.12
clpC1 4039778 c.927A>G synonymous_variant 0.12
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.13
clpC1 4039793 c.912C>G synonymous_variant 0.13
clpC1 4039817 c.888A>C synonymous_variant 0.13
clpC1 4039820 c.885T>G synonymous_variant 0.13
clpC1 4039826 c.879C>G synonymous_variant 0.15
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.14
clpC1 4039838 p.Leu289Ile missense_variant 0.2
clpC1 4039850 c.855T>C synonymous_variant 0.2
clpC1 4039853 p.Leu284Val missense_variant 0.2
clpC1 4039865 c.840T>C synonymous_variant 0.21
clpC1 4039871 c.834C>G synonymous_variant 0.21
clpC1 4039875 p.Asn277Arg missense_variant 0.21
clpC1 4039887 p.Leu273Thr missense_variant 0.21
clpC1 4039889 c.816G>C synonymous_variant 0.21
clpC1 4039898 c.807C>G synonymous_variant 0.25
clpC1 4039901 c.804C>T synonymous_variant 0.25
clpC1 4039904 c.801A>G synonymous_variant 0.26
clpC1 4039929 c.775_776delAGinsTC synonymous_variant 0.17
clpC1 4039934 c.771G>C synonymous_variant 0.16
clpC1 4039937 p.Val256Ile missense_variant 0.16
clpC1 4039940 c.765G>C synonymous_variant 0.16
clpC1 4039946 c.759A>C synonymous_variant 0.15
clpC1 4039949 c.756G>C synonymous_variant 0.15
clpC1 4039952 c.753T>C synonymous_variant 0.15
clpC1 4039955 c.750G>C synonymous_variant 0.15
clpC1 4039960 p.Thr249Ser missense_variant 0.14
clpC1 4039979 c.726C>G synonymous_variant 0.13
clpC1 4039994 p.Glu237Asp missense_variant 0.14
clpC1 4040000 p.His235Lys missense_variant 0.14
clpC1 4040003 c.702G>C synonymous_variant 0.14
clpC1 4040009 c.696C>G synonymous_variant 0.14
clpC1 4040015 c.690G>C synonymous_variant 0.14
clpC1 4040021 c.684A>G synonymous_variant 0.14
clpC1 4040024 c.681A>G synonymous_variant 0.13
clpC1 4040033 c.672G>C synonymous_variant 0.18
clpC1 4040069 c.636G>C synonymous_variant 0.13
embC 4240671 p.Thr270Ile missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242970 c.-263C>T upstream_gene_variant 1.0
embA 4244220 c.988C>T synonymous_variant 1.0
embB 4246551 p.Asn13Ser missense_variant 1.0
embB 4246864 c.351C>T synonymous_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
aftB 4267100 c.1737C>T synonymous_variant 1.0
aftB 4267858 p.Ile327Val missense_variant 1.0
aftB 4269351 c.-515C>T upstream_gene_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
fbiC 1305494 c.2565_*56delCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN frameshift_variant&stop_lost&splice_region_variant 1.0