TB-Profiler result

Run: 6cd10de4-cae5-4617-b104-b84f18eb5061
Summary

Run ID: 6cd10de4-cae5-4617-b104-b84f18eb5061

Sample name:

Date: 24-11-2023 20:19:47

Number of reads: 176954

Percentage reads mapped: 45.47

Median coverage: 9

Strain: lineage4.2.2.2

Spoligotype:

Drug-resistance: RR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.2 Euro-American None 0.9
lineage4.2.2 Euro-American (Ural) None 1.0
lineage4.2.2.2 Euro-American (Ural) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB p.Asn437Thr Uncertain significance
p.Ser441Ala Assoc w R - interim
p.Ser450Phe Assoc w R
isoniazid
ethambutol embB p.His1002Arg Uncertain significance
pyrazinamide
moxifloxacin
levofloxacin
bedaquiline
delamanid
pretomanid
linezolid
streptomycin
amikacin
kanamycin
capreomycin
clofazimine
ethionamide
para-aminosalicylic_acid
cycloserine
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpoB 761116 p.Asn437Thr missense_variant 0.3 rifampicin Uncertain significance
rpoB 761127 p.Ser441Ala missense_variant 0.3 rifampicin Assoc w R - interim
rpoB 761155 p.Ser450Phe missense_variant 0.7 rifampicin Assoc w R
embB 4249518 p.His1002Arg missense_variant 0.9 ethambutol Uncertain significance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrA 7362 p.Glu21Gln missense_variant 1.0 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 fluoroquinolones
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
ciprofloxacin
ofloxacin
mshA 576077 c.730C>T synonymous_variant 1.0 ethionamide
isoniazid
rpoB 760172 c.366G>C synonymous_variant 0.12 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.11 rifampicin
rpoB 760184 c.378A>G synonymous_variant 0.11 rifampicin
rpoB 760196 c.390C>G synonymous_variant 0.13 rifampicin
rpoB 760207 p.Ile134Thr missense_variant 0.17 rifampicin
rpoB 760212 p.Asn136His missense_variant 0.21 rifampicin
rpoB 760216 p.Asn137Thr missense_variant 0.21 rifampicin
rpoB 760223 c.417T>C synonymous_variant 0.22 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.2 rifampicin
rpoB 760263 p.Met153Val missense_variant 0.21 rifampicin Uncertain significance
rpoB 760274 p.Glu156Asp missense_variant 0.25 rifampicin Uncertain significance
rpoB 760283 c.477G>C synonymous_variant 0.25 rifampicin
rpoB 760298 c.492G>C synonymous_variant 0.29 rifampicin
rpoB 760307 c.501T>G synonymous_variant 0.29 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.29 rifampicin
rpoB 760317 c.511_512delAGinsTC synonymous_variant 0.3 rifampicin
rpoB 760325 c.519G>C synonymous_variant 0.3 rifampicin
rpoB 760331 c.525G>T synonymous_variant 0.3 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.32 rifampicin
rpoB 760343 c.537G>T synonymous_variant 0.3 rifampicin
rpoB 760353 p.Glu183Gln missense_variant 0.33 rifampicin
rpoB 760356 p.Thr184Ser missense_variant 0.33 rifampicin
rpoB 760359 p.Ile185Val missense_variant 0.33 rifampicin
rpoB 760368 p.Ser188Thr missense_variant 0.33 rifampicin
rpoB 760378 c.573dupG frameshift_variant 0.32 rifampicin
rpoB 760398 p.Val198Ile missense_variant 0.3 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.32 rifampicin
rpoB 760415 c.609C>T synonymous_variant 0.33 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.33 rifampicin
rpoB 760430 c.624T>C synonymous_variant 0.33 rifampicin
rpoB 760457 c.651C>T synonymous_variant 0.22 rifampicin
rpoB 760460 c.654G>C synonymous_variant 0.18 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.2 rifampicin
rpoB 760481 c.675G>C synonymous_variant 0.23 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.23 rifampicin
rpoB 760514 c.708C>G synonymous_variant 0.17 rifampicin
rpoB 761051 c.1245G>C synonymous_variant 0.3 rifampicin
rpoB 761054 c.1248G>C synonymous_variant 0.3 rifampicin
rpoB 761060 c.1254C>G synonymous_variant 0.3 rifampicin
rpoB 761063 c.1257C>G synonymous_variant 0.3 rifampicin
rpoB 761088 c.1282_1284delAGCinsTCG synonymous_variant 0.3 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.3 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.3 rifampicin
rpoB 761124 p.Leu440Ile missense_variant 0.3 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 0.3 rifampicin
rpoB 761133 c.1327T>C synonymous_variant 0.3 rifampicin
rpoB 761138 c.1332C>G synonymous_variant 0.27 rifampicin
rpoB 761150 c.1344A>G synonymous_variant 0.3 rifampicin
rpoB 761153 c.1347G>C synonymous_variant 0.3 rifampicin
rpoB 761162 c.1356G>C synonymous_variant 0.3 rifampicin
rpoB 761165 c.1359G>A synonymous_variant 0.3 rifampicin
rpoB 761168 c.1362C>G synonymous_variant 0.3 rifampicin
rpoB 761489 c.1683G>A synonymous_variant 1.0 rifampicin
rpoB 761745 p.Val647Leu missense_variant 0.14 rifampicin
rpoB 761749 p.Ser648Cys missense_variant 0.15 rifampicin
rpoB 761760 p.Ile652Val missense_variant 0.14 rifampicin
rpoB 761765 c.1959T>G synonymous_variant 0.17 rifampicin
rpoB 761768 c.1962G>C synonymous_variant 0.15 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.15 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.21 rifampicin
rpoB 761792 c.1986T>G synonymous_variant 0.23 rifampicin
rpoB 761802 p.Met666Leu missense_variant 0.25 rifampicin
rpoB 761806 p.Arg667Gln missense_variant 0.27 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.3 rifampicin
rpoB 761814 p.Ala670Ser missense_variant 0.3 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.3 rifampicin
rpoB 761838 p.Ala678Thr missense_variant 0.3 rifampicin
rpoB 761847 p.Cys681Lys missense_variant 0.3 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.3 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.27 rifampicin
rpoB 761859 p.Asp685Asn missense_variant 0.27 rifampicin
rpoB 761863 p.Ala686Glu missense_variant 0.27 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 0.27 rifampicin
rpoB 761885 c.2079T>G synonymous_variant 0.27 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.27 rifampicin
rpoB 761897 c.2091C>G synonymous_variant 0.3 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.3 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.3 rifampicin
rpoB 761947 p.Leu714Arg missense_variant 0.4 rifampicin
rpoB 761972 c.2166C>G synonymous_variant 0.36 rifampicin
rpoB 762218 c.2412T>C synonymous_variant 0.25 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.25 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.25 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.25 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.21 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.29 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 0.25 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.26 rifampicin
rpoB 762318 p.Ser838Thr missense_variant 0.26 rifampicin
rpoB 762329 c.2523G>C synonymous_variant 0.29 rifampicin
rpoB 762336 p.Ile844Val missense_variant 0.28 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.28 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.26 rifampicin
rpoB 762348 p.Ser848Asn missense_variant 0.26 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.26 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.26 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.26 rifampicin
rpoB 762375 p.Ala857Pro missense_variant 0.26 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.24 rifampicin
rpoC 762398 c.-972T>G upstream_gene_variant 0.24 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.24 rifampicin
rpoC 762404 c.-966T>C upstream_gene_variant 0.25 rifampicin
rpoC 762407 c.-963G>C upstream_gene_variant 0.26 rifampicin
rpoC 762410 c.-960T>G upstream_gene_variant 0.28 rifampicin
rpoC 762416 c.-954A>G upstream_gene_variant 0.28 rifampicin
rpoB 762426 p.Ser874Gln missense_variant 0.28 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 0.28 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.29 rifampicin
rpoC 762452 c.-918G>C upstream_gene_variant 0.29 rifampicin
rpoC 762470 c.-900G>C upstream_gene_variant 0.33 rifampicin
rpoB 762490 p.Val895Ala missense_variant 0.28 rifampicin
rpoB 762507 p.Leu901Thr missense_variant 0.27 rifampicin
rpoB 762511 p.Ala902Glu missense_variant 0.27 rifampicin
rpoC 762527 c.-843G>C upstream_gene_variant 0.25 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.25 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.24 rifampicin
rpoC 762537 c.-833_-831delTTGinsCTC upstream_gene_variant 0.24 rifampicin
rpoC 762560 c.-810A>G upstream_gene_variant 0.22 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.21 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.15 rifampicin
rpoC 762596 c.-774G>C upstream_gene_variant 0.13 rifampicin
rpoC 762920 c.-450C>G upstream_gene_variant 0.27 rifampicin
rpoC 762923 c.-447C>G upstream_gene_variant 0.27 rifampicin
rpoC 762929 c.-441G>C upstream_gene_variant 0.27 rifampicin
rpoC 762995 c.-375G>T upstream_gene_variant 0.3 rifampicin
rpoC 763022 c.-348C>G upstream_gene_variant 0.31 rifampicin
rpoC 763028 c.-342T>C upstream_gene_variant 0.29 rifampicin
rpoC 763031 c.-339T>G upstream_gene_variant 0.31 rifampicin
rpoC 763040 c.-330C>G upstream_gene_variant 0.33 rifampicin
rpoC 763053 c.-317T>C upstream_gene_variant 0.3 rifampicin
rpoC 763058 c.-312C>G upstream_gene_variant 0.3 rifampicin
rpoC 763070 c.-300T>C upstream_gene_variant 0.3 rifampicin
rpoB 763074 p.Thr1090Val missense_variant 0.3 rifampicin
rpoC 763115 c.-255T>C upstream_gene_variant 0.27 rifampicin
rpoC 763127 c.-243G>C upstream_gene_variant 0.25 rifampicin
rpoC 763142 c.-228C>G upstream_gene_variant 0.3 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.27 rifampicin
rpoC 763166 c.-204A>G upstream_gene_variant 0.27 rifampicin
rpoC 763169 c.-201A>G upstream_gene_variant 0.27 rifampicin
rpoC 763172 c.-198G>C upstream_gene_variant 0.25 rifampicin
rpoC 763187 c.-183C>G upstream_gene_variant 0.18 rifampicin
rpoC 763462 c.93G>C synonymous_variant 0.11 rifampicin
rpoC 763465 c.96G>A synonymous_variant 0.15 rifampicin
rpoC 763483 c.114G>C synonymous_variant 0.16 rifampicin
rpoC 763486 c.117T>G synonymous_variant 0.16 rifampicin
rpoC 763504 c.135C>G synonymous_variant 0.16 rifampicin
rpoC 763507 c.138G>C synonymous_variant 0.16 rifampicin
rpoC 763528 c.159G>T synonymous_variant 0.16 rifampicin
rpoC 763534 c.165T>C synonymous_variant 0.16 rifampicin
rpoC 763537 c.168C>G synonymous_variant 0.2 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.24 rifampicin
rpoC 763570 c.201G>T synonymous_variant 0.32 rifampicin
rpoC 763573 c.204G>C synonymous_variant 0.32 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.33 rifampicin
rpoC 763615 c.246G>C synonymous_variant 0.28 rifampicin
rpoC 763630 c.261G>C synonymous_variant 0.31 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.31 rifampicin
rpoC 763636 c.267T>C synonymous_variant 0.31 rifampicin
rpoC 763660 c.291T>C synonymous_variant 0.23 rifampicin
rpoC 763666 c.297G>C synonymous_variant 0.25 rifampicin
rpoC 763667 p.Pro100Ser missense_variant 0.25 rifampicin
rpoC 763696 c.327T>C synonymous_variant 0.25 rifampicin
rpoC 763699 c.330G>C synonymous_variant 0.25 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.25 rifampicin
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 0.25 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.25 rifampicin
rpoC 763717 c.348T>C synonymous_variant 0.25 rifampicin
rpoC 763723 c.354G>C synonymous_variant 0.21 rifampicin
rpoC 763732 c.363C>T synonymous_variant 0.2 rifampicin
rpoC 763735 c.366G>C synonymous_variant 0.2 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.2 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.2 rifampicin
rpoC 764239 c.870T>C synonymous_variant 0.11 rifampicin
rpoC 764245 c.876C>G synonymous_variant 0.11 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.11 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.11 rifampicin
rpoC 764286 c.917_918insAA frameshift_variant 0.12 rifampicin
rpoC 764290 c.922_924delTCG conservative_inframe_deletion 0.12 rifampicin
rpoC 764297 p.Met310Gly missense_variant 0.12 rifampicin
rpoC 764312 p.Asp315Asn missense_variant 0.22 rifampicin
rpoC 764315 p.Ala316Cys missense_variant 0.24 rifampicin
rpoC 764326 c.957G>C synonymous_variant 0.28 rifampicin
rpoC 764338 p.Glu323Asp missense_variant 0.29 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.38 rifampicin
rpoC 764371 c.1002G>C synonymous_variant 0.38 rifampicin
rpoC 764377 c.1008C>G synonymous_variant 0.38 rifampicin
rpoC 764380 c.1011G>C synonymous_variant 0.4 rifampicin
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.4 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 0.44 rifampicin
rpoC 764410 c.1041G>C synonymous_variant 0.47 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.47 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.47 rifampicin
rpoC 764434 c.1065A>G synonymous_variant 0.47 rifampicin
rpoC 764435 c.1066A>C synonymous_variant 0.47 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.57 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.57 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.57 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.57 rifampicin
rpoC 764461 c.1092A>G synonymous_variant 0.57 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.71 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.55 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 0.55 rifampicin
rpoC 764533 c.1164C>G synonymous_variant 0.55 rifampicin
rpoC 764536 c.1167G>T synonymous_variant 0.46 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.46 rifampicin
rpoC 764542 c.1173C>G synonymous_variant 0.46 rifampicin
rpoC 764545 c.1176C>G synonymous_variant 0.5 rifampicin
rpoC 764548 c.1179G>T synonymous_variant 0.5 rifampicin
rpoC 764560 c.1191T>G synonymous_variant 0.46 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 0.5 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 0.5 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.53 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 0.47 rifampicin
rpoC 764632 c.1263T>C synonymous_variant 0.41 rifampicin
rpoC 764644 c.1275G>C synonymous_variant 0.41 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.44 rifampicin
rpoC 764662 c.1293G>C synonymous_variant 0.4 rifampicin
rpoC 764695 c.1326T>C synonymous_variant 0.4 rifampicin
rpoC 764701 c.1332C>G synonymous_variant 0.44 rifampicin
rpoC 764705 p.Leu446Glu missense_variant 0.44 rifampicin
rpoC 764714 p.Leu449Val missense_variant 0.44 rifampicin
rpoC 764737 c.1368G>C synonymous_variant 0.47 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.45 rifampicin
rpoC 764764 c.1395T>C synonymous_variant 0.42 rifampicin
rpoC 764780 c.1411_1412delAGinsTC synonymous_variant 0.38 rifampicin
rpoC 764791 c.1422C>G synonymous_variant 0.31 rifampicin
rpoC 764812 c.1443C>G synonymous_variant 0.31 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.31 rifampicin
rpoC 764824 c.1455T>C synonymous_variant 0.38 rifampicin
rpoC 764830 c.1461C>G synonymous_variant 0.33 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.29 rifampicin
rpoC 764863 c.1494G>C synonymous_variant 0.27 rifampicin
rpoC 764872 c.1503A>G synonymous_variant 0.17 rifampicin
rpoC 764875 c.1506C>G synonymous_variant 0.17 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.17 rifampicin
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Uncertain significance
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471916 n.71_72insCT non_coding_transcript_exon_variant 0.3 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471919 n.75_76delAG non_coding_transcript_exon_variant 0.3 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.29 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1471924 n.79C>A non_coding_transcript_exon_variant 0.29 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.48 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.44 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.44 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1471998 n.153G>T non_coding_transcript_exon_variant 0.44 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472005 n.160T>G non_coding_transcript_exon_variant 0.46 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472023 n.178G>C non_coding_transcript_exon_variant 0.33 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472027 n.182C>A non_coding_transcript_exon_variant 0.27 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472028 n.183A>C non_coding_transcript_exon_variant 0.33 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472030 n.185G>C non_coding_transcript_exon_variant 0.17 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472031 n.186G>T non_coding_transcript_exon_variant 0.17 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472032 n.187G>A non_coding_transcript_exon_variant 0.29 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.44 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.44 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472068 n.223T>C non_coding_transcript_exon_variant 0.44 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472069 n.224G>A non_coding_transcript_exon_variant 0.44 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.62 linezolid
kanamycin Uncertain significance
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.68 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.71 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.69 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.69 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.7 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 0.71 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.71 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.65 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472286 n.441C>A non_coding_transcript_exon_variant 0.62 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472305 n.461_466delTCTCTC non_coding_transcript_exon_variant 0.56 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472313 n.469_470delAT non_coding_transcript_exon_variant 0.6 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472328 n.483G>T non_coding_transcript_exon_variant 0.68 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.72 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin Uncertain significance
rrs 1472396 n.551A>T non_coding_transcript_exon_variant 0.64 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.62 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.64 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.6 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472437 n.592T>C non_coding_transcript_exon_variant 0.6 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.6 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472449 n.604C>G non_coding_transcript_exon_variant 0.6 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.6 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472451 n.606C>A non_coding_transcript_exon_variant 0.6 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 0.6 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472461 n.616G>T non_coding_transcript_exon_variant 0.6 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472463 n.618G>C non_coding_transcript_exon_variant 0.61 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472467 n.622G>T non_coding_transcript_exon_variant 0.62 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.65 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.67 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472494 n.649A>T non_coding_transcript_exon_variant 0.69 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.69 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.69 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin Uncertain significance
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.69 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.74 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472583 n.738T>A non_coding_transcript_exon_variant 0.74 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.74 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.77 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.73 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.73 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472671 n.827_828insGACTG non_coding_transcript_exon_variant 0.69 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472677 n.832_833insACGG non_coding_transcript_exon_variant 0.69 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472682 n.838_845delTGGGATCC non_coding_transcript_exon_variant 0.71 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.71 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.73 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472840 n.995A>C non_coding_transcript_exon_variant 0.5 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472841 n.996G>A non_coding_transcript_exon_variant 0.5 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472844 n.999C>T non_coding_transcript_exon_variant 0.5 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472845 n.1000G>C non_coding_transcript_exon_variant 0.5 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472846 n.1001C>G non_coding_transcript_exon_variant 0.5 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472849 n.1004C>A non_coding_transcript_exon_variant 0.48 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.48 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472859 n.1014G>A non_coding_transcript_exon_variant 0.48 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472860 n.1015C>T non_coding_transcript_exon_variant 0.48 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472861 n.1016G>C non_coding_transcript_exon_variant 0.48 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472873 n.1028C>T non_coding_transcript_exon_variant 0.5 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472874 n.1029C>T non_coding_transcript_exon_variant 0.5 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 0.5 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.59 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472953 n.1108G>A non_coding_transcript_exon_variant 0.66 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.66 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.66 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.67 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin Uncertain significance
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.67 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.67 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.67 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.73 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.73 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473094 n.1249T>G non_coding_transcript_exon_variant 0.73 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.73 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.73 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.72 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.72 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.68 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.69 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473129 n.1284C>T non_coding_transcript_exon_variant 0.7 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473201 n.1356A>T non_coding_transcript_exon_variant 0.7 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473202 n.1357C>T non_coding_transcript_exon_variant 0.7 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.52 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.52 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.52 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.52 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.54 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.56 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.56 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.45 linezolid
rrl 1473698 n.41G>A non_coding_transcript_exon_variant 0.47 linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.47 linezolid
rrl 1473743 n.86C>T non_coding_transcript_exon_variant 0.58 linezolid
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.61 linezolid
rrl 1473757 n.100T>G non_coding_transcript_exon_variant 0.61 linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.61 linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.62 linezolid
rrl 1473791 n.134A>C non_coding_transcript_exon_variant 0.6 linezolid
rrl 1473804 n.147T>G non_coding_transcript_exon_variant 0.58 linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.58 linezolid
rrl 1473811 n.154C>A non_coding_transcript_exon_variant 0.58 linezolid
rrl 1473822 n.165A>G non_coding_transcript_exon_variant 0.62 linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.59 linezolid
rrl 1473833 n.176G>T non_coding_transcript_exon_variant 0.59 linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.59 linezolid Uncertain significance
rrl 1473862 n.205C>T non_coding_transcript_exon_variant 0.52 linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.48 linezolid
rrl 1473886 n.229A>C non_coding_transcript_exon_variant 0.45 linezolid
rrl 1473888 n.231T>G non_coding_transcript_exon_variant 0.48 linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.47 linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.47 linezolid
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.4 linezolid
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.43 linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.43 linezolid
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 0.18 linezolid
rrl 1473936 n.279A>G non_coding_transcript_exon_variant 0.18 linezolid
rrl 1473940 n.283A>G non_coding_transcript_exon_variant 0.18 linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.17 linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.18 linezolid
rrl 1473950 n.293G>T non_coding_transcript_exon_variant 0.18 linezolid
rrl 1473953 n.296T>C non_coding_transcript_exon_variant 0.18 linezolid
rrl 1473962 n.305T>C non_coding_transcript_exon_variant 0.17 linezolid
rrl 1474200 n.545delT non_coding_transcript_exon_variant 0.45 linezolid
rrl 1474253 n.596A>T non_coding_transcript_exon_variant 0.64 linezolid
rrl 1474271 n.614A>G non_coding_transcript_exon_variant 0.53 linezolid
rrl 1474286 n.631_634delCCTT non_coding_transcript_exon_variant 0.47 linezolid
rrl 1474348 n.692_699delAGGGACAT non_coding_transcript_exon_variant 0.31 linezolid
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.31 linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.31 linezolid
rrl 1474372 n.719_720dupTG non_coding_transcript_exon_variant 0.31 linezolid
rrl 1474381 n.724T>G non_coding_transcript_exon_variant 0.33 linezolid
rrl 1474387 n.730C>G non_coding_transcript_exon_variant 0.33 linezolid
rrl 1474406 n.749T>G non_coding_transcript_exon_variant 0.31 linezolid
rrl 1474412 n.756_782delACCCACACGCGCATACGCGCGTGTGAA non_coding_transcript_exon_variant 0.33 linezolid
rrl 1474444 n.787G>C non_coding_transcript_exon_variant 0.31 linezolid
rrl 1474450 n.793T>G non_coding_transcript_exon_variant 0.33 linezolid
rrl 1474452 n.795C>G non_coding_transcript_exon_variant 0.33 linezolid
rrl 1474453 n.796T>C non_coding_transcript_exon_variant 0.36 linezolid
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.33 linezolid
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.33 linezolid
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.7 linezolid
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.6 linezolid
rrl 1474528 n.871T>A non_coding_transcript_exon_variant 0.6 linezolid
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.58 linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.54 linezolid
rrl 1474540 n.883T>C non_coding_transcript_exon_variant 0.54 linezolid
rrl 1474541 n.884G>T non_coding_transcript_exon_variant 0.52 linezolid
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.52 linezolid
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.53 linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.59 linezolid
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 0.58 linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.58 linezolid
rrl 1474640 n.983C>G non_coding_transcript_exon_variant 0.58 linezolid
rrl 1474641 n.984G>T non_coding_transcript_exon_variant 0.58 linezolid
rrl 1474643 n.986A>G non_coding_transcript_exon_variant 0.59 linezolid
rrl 1474651 n.995delT non_coding_transcript_exon_variant 0.61 linezolid
rrl 1474658 n.1001A>T non_coding_transcript_exon_variant 0.63 linezolid
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.63 linezolid
rrl 1474675 n.1018C>T non_coding_transcript_exon_variant 0.61 linezolid
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.61 linezolid
rrl 1474705 n.1048_1049insAC non_coding_transcript_exon_variant 0.62 linezolid
rrl 1474709 n.1052G>T non_coding_transcript_exon_variant 0.6 linezolid Uncertain significance
rrl 1474712 n.1056delT non_coding_transcript_exon_variant 0.62 linezolid
rrl 1474716 n.1059A>G non_coding_transcript_exon_variant 0.62 linezolid
rrl 1474743 n.1086T>G non_coding_transcript_exon_variant 0.62 linezolid
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.6 linezolid
rrl 1474752 n.1096delA non_coding_transcript_exon_variant 0.61 linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.6 linezolid
rrl 1474777 n.1120T>A non_coding_transcript_exon_variant 0.61 linezolid
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.61 linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.63 linezolid
rrl 1474798 n.1141C>T non_coding_transcript_exon_variant 0.6 linezolid
rrl 1474806 n.1149A>T non_coding_transcript_exon_variant 0.58 linezolid
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.59 linezolid
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.59 linezolid
rrl 1474825 n.1168G>A non_coding_transcript_exon_variant 0.59 linezolid
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.59 linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.59 linezolid
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.52 linezolid
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.38 linezolid
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.33 linezolid
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.33 linezolid
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.33 linezolid
rrl 1474928 n.1271C>G non_coding_transcript_exon_variant 0.17 linezolid
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.17 linezolid
rrl 1475499 n.1842C>G non_coding_transcript_exon_variant 0.18 linezolid
rrl 1475526 n.1869C>T non_coding_transcript_exon_variant 0.17 linezolid
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 0.17 linezolid
rrl 1475538 n.1881T>G non_coding_transcript_exon_variant 0.18 linezolid
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.18 linezolid
rrl 1475542 n.1885A>G non_coding_transcript_exon_variant 0.18 linezolid
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.18 linezolid
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.18 linezolid
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.2 linezolid
rrl 1475562 n.1905C>T non_coding_transcript_exon_variant 0.29 linezolid
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.25 linezolid
rrl 1475601 n.1945_1947delGGA non_coding_transcript_exon_variant 0.24 linezolid
rrl 1475609 n.1952C>G non_coding_transcript_exon_variant 0.25 linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 0.25 linezolid
rrl 1475620 n.1963T>G non_coding_transcript_exon_variant 0.27 linezolid
rrl 1475633 n.1976G>T non_coding_transcript_exon_variant 0.21 linezolid
rrl 1475636 n.1979A>T non_coding_transcript_exon_variant 0.21 linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 0.21 linezolid
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 0.21 linezolid
rrl 1475639 n.1982C>T non_coding_transcript_exon_variant 0.21 linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.21 linezolid
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.2 linezolid
rrl 1475650 n.1993A>G non_coding_transcript_exon_variant 0.2 linezolid
rrl 1475655 n.1998T>G non_coding_transcript_exon_variant 0.2 linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.2 linezolid
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.24 linezolid
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.41 linezolid
rrl 1475740 n.2083G>C non_coding_transcript_exon_variant 0.5 linezolid
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 0.5 linezolid
rrl 1475788 n.2131C>G non_coding_transcript_exon_variant 0.53 linezolid
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.66 linezolid
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.66 linezolid
rrl 1475892 n.2235A>G non_coding_transcript_exon_variant 0.66 linezolid
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.68 linezolid
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.68 linezolid
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.7 linezolid
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.7 linezolid Uncertain significance
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.71 linezolid
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.69 linezolid
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.67 linezolid
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.62 linezolid
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.59 linezolid
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.57 linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.55 linezolid Uncertain significance
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.52 linezolid Uncertain significance
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.52 linezolid
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.5 linezolid
rrl 1476026 n.2369T>G non_coding_transcript_exon_variant 0.57 linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.57 linezolid
rrl 1476033 n.2376T>A non_coding_transcript_exon_variant 0.57 linezolid
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 0.57 linezolid
rrl 1476040 n.2383C>T non_coding_transcript_exon_variant 0.59 linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.61 linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.61 linezolid
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.57 linezolid
rrl 1476081 n.2424A>T non_coding_transcript_exon_variant 0.55 linezolid
rrl 1476082 n.2425T>C non_coding_transcript_exon_variant 0.55 linezolid
rrl 1476091 n.2434_2435insG non_coding_transcript_exon_variant 0.54 linezolid
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.5 linezolid
rrl 1476100 n.2443A>G non_coding_transcript_exon_variant 0.5 linezolid
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.52 linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.56 linezolid
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.5 linezolid
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.56 linezolid
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.56 linezolid
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.56 linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.54 linezolid
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.54 linezolid
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.5 linezolid
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.49 linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.44 linezolid
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.44 linezolid
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.44 linezolid
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.48 linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.41 linezolid
rrl 1476255 n.2598A>G non_coding_transcript_exon_variant 0.38 linezolid
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.38 linezolid
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.38 linezolid Uncertain significance
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 0.37 linezolid
rrl 1476268 n.2611A>G non_coding_transcript_exon_variant 0.38 linezolid
rrl 1476275 n.2618T>C non_coding_transcript_exon_variant 0.38 linezolid
rrl 1476276 n.2619C>A non_coding_transcript_exon_variant 0.38 linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.38 linezolid
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.4 linezolid
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.4 linezolid
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.4 linezolid
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.4 linezolid
rrl 1476301 n.2644A>G non_coding_transcript_exon_variant 0.4 linezolid
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.47 linezolid
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.59 linezolid
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.61 linezolid
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.62 linezolid
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.61 linezolid
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.56 linezolid
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.56 linezolid
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.56 linezolid
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 0.56 linezolid
rrl 1476534 n.2877A>C non_coding_transcript_exon_variant 0.56 linezolid
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.6 linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.6 linezolid
rrl 1476573 n.2916A>G non_coding_transcript_exon_variant 0.56 linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.33 linezolid
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.33 linezolid
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.32 linezolid
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.28 linezolid
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.28 linezolid
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.28 linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.28 linezolid
rrl 1476621 n.2964C>T non_coding_transcript_exon_variant 0.29 linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.29 linezolid
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.29 linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.29 linezolid
rpsA 1833829 c.288A>G synonymous_variant 0.3 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.3 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.27 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.36 pyrazinamide
rpsA 1833859 c.318C>T synonymous_variant 0.36 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.44 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.43 pyrazinamide
rpsA 1833914 p.Ala125Pro missense_variant 0.46 pyrazinamide
rpsA 1833919 c.378C>G synonymous_variant 0.43 pyrazinamide
rpsA 1833920 p.Lys127Arg missense_variant 0.43 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.47 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.5 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 0.5 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.47 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.47 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.44 pyrazinamide
rpsA 1833995 c.454C>T synonymous_variant 0.41 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.39 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.39 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.39 pyrazinamide
rpsA 1834022 c.481C>T synonymous_variant 0.41 pyrazinamide
rpsA 1834034 p.Ile165Val missense_variant 0.41 pyrazinamide
rpsA 1834040 p.Lys167Arg missense_variant 0.41 pyrazinamide
rpsA 1834046 p.Ile169Leu missense_variant 0.39 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 0.39 pyrazinamide
rpsA 1834093 c.552G>C synonymous_variant 0.33 pyrazinamide
rpsA 1834135 c.594G>C synonymous_variant 0.18 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.17 pyrazinamide
rpsA 1834255 c.714C>G synonymous_variant 0.15 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.17 pyrazinamide
rpsA 1834264 c.723G>C synonymous_variant 0.18 pyrazinamide
rpsA 1834286 c.745_746delTCinsAG synonymous_variant 0.25 pyrazinamide
rpsA 1834327 c.786G>C synonymous_variant 0.3 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.2 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.17 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.17 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.17 pyrazinamide
rpsA 1834477 c.936C>G synonymous_variant 0.17 pyrazinamide
rpsA 1834480 c.939C>G synonymous_variant 0.17 pyrazinamide
rpsA 1834483 p.Glu314Asp missense_variant 0.17 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.15 pyrazinamide
rpsA 1834504 c.963G>C synonymous_variant 0.15 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.15 pyrazinamide
rpoA 3878337 c.171T>C synonymous_variant 0.17 rifampicin
clpC1 4038755 c.1950G>T synonymous_variant 0.27 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.27 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.27 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.27 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.3 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.27 pyrazinamide
clpC1 4038794 p.Ser637Thr missense_variant 0.27 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.27 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.27 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.3 pyrazinamide
clpC1 4038863 c.1842G>C synonymous_variant 0.3 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.36 pyrazinamide
clpC1 4038881 c.1824C>T synonymous_variant 0.36 pyrazinamide
clpC1 4038896 c.1809C>T synonymous_variant 0.33 pyrazinamide
clpC1 4038905 c.1800A>C synonymous_variant 0.33 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.33 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.36 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.36 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.33 pyrazinamide
clpC1 4038932 c.1773G>C synonymous_variant 0.27 pyrazinamide
clpC1 4038939 p.Phe589Tyr missense_variant 0.25 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.25 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.25 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.23 pyrazinamide
clpC1 4038971 p.Ile578Val missense_variant 0.21 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.21 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 0.23 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.21 pyrazinamide
clpC1 4039001 p.Asn568Glu missense_variant 0.15 pyrazinamide
clpC1 4039004 c.1701C>G synonymous_variant 0.15 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.25 pyrazinamide
clpC1 4039034 c.1671C>G synonymous_variant 0.18 pyrazinamide
clpC1 4039046 c.1659C>T synonymous_variant 0.18 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.21 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.2 pyrazinamide
clpC1 4039091 c.1614G>T synonymous_variant 0.2 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.31 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.33 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.33 pyrazinamide
clpC1 4039117 p.Lys530Gln missense_variant 0.31 pyrazinamide
clpC1 4039118 c.1587C>G synonymous_variant 0.31 pyrazinamide
clpC1 4039121 c.1584T>G synonymous_variant 0.31 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 0.31 pyrazinamide
clpC1 4039139 p.Glu522Asp missense_variant 0.31 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.31 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.31 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.15 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.15 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.15 pyrazinamide
clpC1 4039181 c.1522_1524delTTGinsCTC synonymous_variant 0.15 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 0.15 pyrazinamide
clpC1 4039217 c.1488G>C synonymous_variant 0.15 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.15 pyrazinamide
clpC1 4039238 p.Gly489Ala missense_variant 0.18 pyrazinamide
clpC1 4039253 c.1452C>T synonymous_variant 0.2 pyrazinamide
clpC1 4039646 c.1059G>A synonymous_variant 0.38 pyrazinamide
clpC1 4039651 p.Val352Leu missense_variant 0.38 pyrazinamide
clpC1 4039654 p.Thr351Ser missense_variant 0.38 pyrazinamide
clpC1 4039655 c.1050G>C synonymous_variant 0.38 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.36 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.36 pyrazinamide
clpC1 4039670 p.Val345Ile missense_variant 0.36 pyrazinamide
clpC1 4039697 p.Ala336Pro missense_variant 0.33 pyrazinamide
clpC1 4039711 p.Ile332Val missense_variant 0.36 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.38 pyrazinamide
clpC1 4039727 p.Asp326Glu missense_variant 0.38 pyrazinamide
clpC1 4039730 c.975C>G synonymous_variant 0.38 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.33 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.36 pyrazinamide
clpC1 4039754 c.951G>C synonymous_variant 0.36 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.36 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.36 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.36 pyrazinamide
clpC1 4039773 p.Lys311Met missense_variant 0.36 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.36 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.36 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.36 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.36 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.4 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.31 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 0.31 pyrazinamide
clpC1 4039823 c.882T>C synonymous_variant 0.31 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.31 pyrazinamide
clpC1 4039838 p.Leu289Ile missense_variant 0.31 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.31 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.33 pyrazinamide
clpC1 4039874 p.Asn277Lys missense_variant 0.41 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.41 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.38 pyrazinamide
clpC1 4039929 c.775_776delAGinsTC synonymous_variant 0.27 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.33 pyrazinamide
clpC1 4039946 c.759A>G synonymous_variant 0.33 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.31 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.31 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.31 pyrazinamide
clpC1 4040000 p.His235Lys missense_variant 0.33 pyrazinamide
clpC1 4040003 c.702G>C synonymous_variant 0.33 pyrazinamide
clpC1 4040008 p.Ile233Val missense_variant 0.33 pyrazinamide
clpC1 4040009 p.Ala232Lys missense_variant 0.33 pyrazinamide
clpC1 4040021 c.684A>G synonymous_variant 0.33 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 0.33 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.33 pyrazinamide
clpC1 4040053 p.Pro218Ala missense_variant 0.33 pyrazinamide
clpC1 4040066 c.639G>C synonymous_variant 0.31 pyrazinamide
clpC1 4040090 c.615T>G synonymous_variant 0.21 pyrazinamide
clpC1 4040096 c.609G>C synonymous_variant 0.2 pyrazinamide
clpC1 4040107 p.Val200Ile missense_variant 0.2 pyrazinamide
clpC1 4040117 c.588A>G synonymous_variant 0.23 pyrazinamide
clpC1 4040129 c.576C>T synonymous_variant 0.17 pyrazinamide
embA 4242643 c.-590C>T upstream_gene_variant 1.0 ethambutol
ethA 4328317 c.-844C>T upstream_gene_variant 1.0 ethionamide