TB-Profiler result

Run: ERR3439432
Summary

Run ID: ERR3439432

Sample name:

Date: 2024-10-03T17:48:58.767013

Number of reads: 262832

Percentage reads mapped: 29.64

Median coverage: 9.0

Strain: M.canetti;lineage4.6.4;lineage4.9

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.6.4 Euro-American None 0.06
lineage4 Euro-American None 0.85
lineage4.9 Euro-American (H37Rv-like) None 0.89
M.canetti M.canetti None 0.05
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.His312Arg Mutation from literature
p.Tyr384Asn Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
embB 4247448 p.His312Arg missense_variant 1.0 ethambutol Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 1.0 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 1161 c.1161A>G synonymous_variant 1.0 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 1.0 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1179 c.1179G>C synonymous_variant 1.0 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 1.0 isoniazid
dnaA 1194 c.1194G>C synonymous_variant 1.0 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 1.0 isoniazid
dnaA 1200 c.1200C>T synonymous_variant 1.0 isoniazid
dnaA 1206 c.1206G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1220 p.Asn407Thr missense_variant 1.0 isoniazid
dnaA 1222 p.Thr408Ala missense_variant 1.0 isoniazid Uncertain significance
dnaA 1245 c.1245G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 1.0 isoniazid
dnaA 1302 c.1302C>G synonymous_variant 1.0 isoniazid
dnaA 1332 c.1332A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1338 c.1338T>C synonymous_variant 1.0 isoniazid
dnaA 1350 c.1350G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1353 c.1353T>C synonymous_variant 1.0 isoniazid
dnaA 1356 c.1356T>G synonymous_variant 1.0 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 1.0 isoniazid
dnaA 1374 c.1374G>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1375 c.1375T>C synonymous_variant 1.0 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 1.0 isoniazid
dnaA 1389 c.1389C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1392 c.1392A>G synonymous_variant 1.0 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 1.0 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 1.0 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 1.0 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 1.0 isoniazid
gyrB 6049 c.810G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6052 c.813T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6055 c.816T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6067 c.828G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6073 c.834T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6079 c.840C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6085 c.846C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6086 p.Thr283Pro missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6097 c.858G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6121 c.882C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6145 c.906C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6178 c.939C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6181 c.942C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6196 c.957C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6247 c.1008G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6259 p.Asp340Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6299 c.1060C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6313 c.-989C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6358 c.1119C>G synonymous_variant 1.0 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6361 c.-941G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6400 c.-902C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6674 c.-628_-626delCTTinsTTG upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7151 c.1912C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7165 c.-137C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7532 c.231T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7619 c.318C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7622 c.321C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7766 c.465C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7769 c.468C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7838 c.537C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7850 c.549C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7889 c.588G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7919 p.Glu206Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7923 p.His208Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7940 c.639G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7941 p.Glu214Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7946 c.645C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8105 c.804G>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8189 c.888G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8195 c.894C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 p.Ser300Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8217 p.Ser306Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8225 p.Asp308Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8235 p.Leu312Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8258 c.957G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8282 c.981G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8315 c.1014G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8318 c.1017C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8402 p.Asp367Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8421 p.Val374Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8447 c.1146C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8450 c.1149G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8561 c.1260A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8562 c.1261C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8571 c.1270C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8609 c.1308G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8633 c.1332C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8666 c.1365G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8694 c.1393C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8723 c.1422G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8732 c.1431G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8752 p.Ala484Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8795 c.1494C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8796 p.Ile499Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8813 c.1512C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8825 c.1524G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8876 c.1575C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>A synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9218 c.1917C>T synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9257 c.1956C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9323 c.2022C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9449 c.2148C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9452 c.2151G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9476 c.2175G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9479 c.2178G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9485 c.2184A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9488 c.2187G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9491 c.2190C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9494 c.2193T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9497 c.2196G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9503 c.2202T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9518 c.2217A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9527 c.2226A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9542 c.2241T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9545 c.2244A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9551 c.2250G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9566 c.2265C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9585 c.2284T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9626 c.2325T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9629 c.2328C>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9630 p.Val777Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9656 c.2355C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9659 c.2358C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9668 c.2367C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
fgd1 490962 c.180T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490971 c.189A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490974 c.192T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490980 p.Asn66Lys missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490984 p.Leu68Val missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490995 c.213C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490998 c.216T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491007 c.225G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491013 c.231C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491043 c.261T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491049 c.267T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491063 p.Gly94Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491067 c.285C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fgd1 491077 p.Asn99Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491085 c.303T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491091 c.309T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491094 c.312C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491106 c.324T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491142 c.360C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491191 p.Gly137Arg missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491196 c.414A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491203 p.Gln141Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491212 p.Ser144Arg missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491226 c.444C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491241 p.Asp153Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491259 c.477T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491265 c.483G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491604 c.822G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
mshA 575506 c.159C>T synonymous_variant 0.9 isoniazid
ethionamide
mshA 575512 c.165A>G synonymous_variant 0.91 isoniazid
ethionamide
mshA 575521 c.174A>C synonymous_variant 0.91 isoniazid
ethionamide
mshA 575530 c.183C>G synonymous_variant 0.91 isoniazid
ethionamide
mshA 575536 c.189T>C synonymous_variant 0.91 isoniazid
ethionamide
mshA 575539 c.192C>T synonymous_variant 0.91 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575548 c.201C>A synonymous_variant 0.85 isoniazid
ethionamide
mshA 575561 p.Met72Val missense_variant 0.85 isoniazid
ethionamide
mshA 575586 p.Ala80Gly missense_variant 0.85 isoniazid
ethionamide
mshA 575590 c.243T>G synonymous_variant 0.85 isoniazid
ethionamide
mshA 575593 c.246G>A synonymous_variant 0.85 isoniazid
ethionamide
mshA 575596 c.249C>T synonymous_variant 0.85 isoniazid
ethionamide
mshA 575629 c.282A>T synonymous_variant 0.93 isoniazid
ethionamide
mshA 575633 p.Ala96Thr missense_variant 0.93 isoniazid
ethionamide
mshA 575659 c.312A>G synonymous_variant 0.9 isoniazid
ethionamide
mshA 575686 c.339G>A synonymous_variant 0.92 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 0.92 isoniazid
ethionamide
mshA 575692 c.345G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575713 c.366G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575732 c.385_387delCTTinsTTG synonymous_variant 1.0 isoniazid
ethionamide
mshA 575737 c.390T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575746 c.399C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575767 c.420G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575770 c.423G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575772 p.Val142Ala missense_variant 1.0 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575821 c.474G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575824 c.477T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575842 c.495G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575848 c.501C>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575872 c.525C>T synonymous_variant 1.0 isoniazid
ethionamide
ccsA 620245 p.Leu119Met missense_variant 0.87 kanamycin
capreomycin
amikacin
ccsA 620256 c.366C>G synonymous_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620257 p.Ile123Val missense_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620271 c.381C>G synonymous_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620283 c.393T>C synonymous_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620284 p.Ala132Pro missense_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620288 p.Arg133Gln missense_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620290 p.Tyr134Asn missense_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620295 c.405G>T synonymous_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620314 c.424C>T synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin
amikacin Not assoc w R - Interim
ccsA 620325 c.435G>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620337 c.447C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620358 c.468C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620397 c.507C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620685 c.795G>A synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin
Rv0565c 656922 p.Ile183Val missense_variant 1.0 ethionamide
Rv0565c 657678 c.-208A>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657686 c.-216C>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>T synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.92 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.91 rifampicin
nusG 734616 c.363C>A synonymous_variant 0.93 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.93 rifampicin
nusG 734631 c.378G>A synonymous_variant 0.93 rifampicin
nusG 734634 c.381G>C synonymous_variant 0.93 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.93 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.93 rifampicin
nusG 734661 c.408A>C synonymous_variant 0.93 rifampicin
nusG 734664 c.411T>G synonymous_variant 0.93 rifampicin
nusG 734670 c.417G>A synonymous_variant 0.93 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.93 rifampicin
nusG 734680 p.Ala143Ser missense_variant 0.94 rifampicin
nusG 734703 c.450T>C synonymous_variant 0.93 rifampicin
nusG 734709 c.456T>G synonymous_variant 0.93 rifampicin
nusG 734712 c.459G>C synonymous_variant 0.93 rifampicin
nusG 734718 c.465G>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
nusG 734719 p.Ser156Ala missense_variant 0.92 rifampicin
nusG 734722 p.Thr157Ala missense_variant 1.0 rifampicin
nusG 734726 p.Arg158Lys missense_variant 1.0 rifampicin
nusG 734733 c.480T>A synonymous_variant 1.0 rifampicin
nusG 734736 c.483C>G synonymous_variant 1.0 rifampicin
nusG 734754 c.501G>C synonymous_variant 0.92 rifampicin
nusG 734757 c.504T>C synonymous_variant 0.92 rifampicin
nusG 734762 p.Ala170Val missense_variant 0.92 rifampicin
nusG 734769 c.516G>A synonymous_variant 0.92 rifampicin
nusG 734826 c.573A>C synonymous_variant 0.91 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.91 rifampicin
nusG 734865 c.612G>C synonymous_variant 0.91 rifampicin
nusG 734874 c.621G>A synonymous_variant 0.91 rifampicin
nusG 734880 c.627C>T synonymous_variant 0.9 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.9 rifampicin
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760172 c.366G>C synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760193 c.387C>G synonymous_variant 1.0 rifampicin
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760202 c.396G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 1.0 rifampicin
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760343 c.537G>C synonymous_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760445 c.639C>T synonymous_variant 1.0 rifampicin
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760508 c.702G>C synonymous_variant 1.0 rifampicin
rpoB 760511 c.705G>C synonymous_variant 1.0 rifampicin
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760577 c.771G>A synonymous_variant 1.0 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760604 c.798G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760607 c.801G>C synonymous_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760625 c.819C>A synonymous_variant 1.0 rifampicin
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760664 c.858G>C synonymous_variant 1.0 rifampicin
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ala missense_variant 1.0 rifampicin
rpoB 760859 c.1053T>G synonymous_variant 1.0 rifampicin
rpoB 760868 c.1062C>G synonymous_variant 1.0 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760920 c.1114C>T synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760971 c.1165C>A synonymous_variant 0.92 rifampicin
rpoB 760994 c.1188G>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>T synonymous_variant 0.93 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>A synonymous_variant 0.91 rifampicin
rpoB 761037 c.1231T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761066 c.1260G>C synonymous_variant 0.94 rifampicin
rpoB 761096 c.1290G>C synonymous_variant 1.0 rifampicin
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327_1329delTTGinsCTC synonymous_variant 1.0 rifampicin
rpoB 761150 c.1344A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>T synonymous_variant 1.0 rifampicin
rpoB 761168 c.1362C>G synonymous_variant 0.96 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761183 c.1377T>G synonymous_variant 0.96 rifampicin
rpoB 761201 c.1395G>A synonymous_variant 0.95 rifampicin
rpoB 761204 c.1398C>G synonymous_variant 0.95 rifampicin
rpoB 761207 c.1401C>T synonymous_variant 0.95 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>G synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>G synonymous_variant 1.0 rifampicin
rpoB 761603 c.1797C>T synonymous_variant 1.0 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.94 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 1.0 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 1.0 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 1.0 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 1.0 rifampicin
rpoB 761990 c.2184G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 1.0 rifampicin
rpoB 762011 c.2205G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762020 c.2214G>A synonymous_variant 1.0 rifampicin
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 1.0 rifampicin
rpoB 762224 c.2418C>G synonymous_variant 1.0 rifampicin
rpoB 762236 c.2430G>A synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 1.0 rifampicin
rpoB 762269 c.2463G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762278 c.2472C>G synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762486 p.Pro894Ala missense_variant 1.0 rifampicin
rpoB 762489 p.Val895Gln missense_variant 1.0 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 1.0 rifampicin Uncertain significance
rpoC 762518 c.-852C>G upstream_gene_variant 1.0 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762776 c.-594C>T upstream_gene_variant 1.0 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 1.0 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762830 c.-540C>T upstream_gene_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762860 c.-510G>T upstream_gene_variant 0.94 rifampicin
rpoB 762899 c.3093G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763050 c.-320C>T upstream_gene_variant 0.93 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>T upstream_gene_variant 0.94 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763124 c.-246C>T upstream_gene_variant 1.0 rifampicin
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.91 rifampicin
rpoC 763430 c.61A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763435 c.66A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763505 c.136C>T synonymous_variant 1.0 rifampicin
rpoC 763561 c.192G>A synonymous_variant 1.0 rifampicin
rpoC 763600 c.231C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763606 c.237C>T synonymous_variant 1.0 rifampicin
rpoC 763618 c.249C>A synonymous_variant 1.0 rifampicin
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>G synonymous_variant 1.0 rifampicin
rpoC 763639 c.270G>A synonymous_variant 1.0 rifampicin
rpoC 763658 c.289_291delCTTinsTTG synonymous_variant 1.0 rifampicin
rpoC 763666 c.297G>A synonymous_variant 1.0 rifampicin
rpoC 763696 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>C synonymous_variant 1.0 rifampicin
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763735 c.366G>C synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763781 p.Ser138Ala missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763819 c.450G>C synonymous_variant 1.0 rifampicin
rpoC 763835 p.Ala156Met missense_variant 1.0 rifampicin
rpoC 763855 c.486C>T synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763867 c.498C>G synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763877 c.508_510delCTAinsTTG synonymous_variant 1.0 rifampicin
rpoC 763882 c.513G>A synonymous_variant 1.0 rifampicin
rpoC 763885 c.516C>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>C synonymous_variant 1.0 rifampicin
rpoC 763891 c.522G>C synonymous_variant 1.0 rifampicin
rpoC 763916 p.Glu183Gln missense_variant 1.0 rifampicin
rpoC 763945 c.576T>C synonymous_variant 1.0 rifampicin
rpoC 763948 c.579G>C synonymous_variant 1.0 rifampicin
rpoC 763951 c.582G>A synonymous_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 1.0 rifampicin
rpoC 764119 c.750G>A synonymous_variant 1.0 rifampicin
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764140 c.771C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764161 c.792G>C synonymous_variant 1.0 rifampicin
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 1.0 rifampicin
rpoC 764254 c.885G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764269 c.900G>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>T synonymous_variant 1.0 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764404 c.1035C>A synonymous_variant 1.0 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 1.0 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764587 c.1218C>G synonymous_variant 0.93 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764674 c.1305G>A synonymous_variant 0.94 rifampicin
rpoC 764681 c.1312C>T synonymous_variant 0.95 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764755 c.1386C>T synonymous_variant 1.0 rifampicin
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764767 c.1398G>C synonymous_variant 1.0 rifampicin
rpoC 764791 c.1422C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764800 c.1431G>A synonymous_variant 1.0 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 1.0 rifampicin
rpoC 764833 c.1464A>G synonymous_variant 1.0 rifampicin
rpoC 764872 c.1503A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCTC synonymous_variant 1.0 rifampicin
rpoC 765526 c.2157C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>A synonymous_variant 1.0 rifampicin
rpoC 765547 c.2178C>A synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 1.0 rifampicin
rpoC 765586 c.2217G>A synonymous_variant 1.0 rifampicin
rpoC 765589 c.2220G>C synonymous_variant 1.0 rifampicin
rpoC 765622 p.Glu751Asp missense_variant 1.0 rifampicin
rpoC 765628 c.2259G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765727 c.2358T>C synonymous_variant 1.0 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765748 c.2379C>T synonymous_variant 1.0 rifampicin
rpoC 765752 p.Asp795Ser missense_variant 1.0 rifampicin
rpoC 765757 c.2388C>T synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765790 c.2421C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>A synonymous_variant 1.0 rifampicin
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765910 c.2541G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 1.0 rifampicin
rpoC 765952 c.2583G>C synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765997 c.2628T>C synonymous_variant 1.0 rifampicin
rpoC 766300 c.2931C>G synonymous_variant 1.0 rifampicin
rpoC 766303 c.2934C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766306 c.2937C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>C synonymous_variant 1.0 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766324 c.2955C>T synonymous_variant 1.0 rifampicin
rpoC 766351 c.2982C>G synonymous_variant 1.0 rifampicin
rpoC 766360 c.2991C>T synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766387 c.3018C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766397 c.3028C>T synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766417 c.3048C>T synonymous_variant 0.92 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.9 rifampicin
rpoC 766519 c.3150C>A synonymous_variant 0.9 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.9 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 0.9 rifampicin
rpoC 766537 c.3168G>A synonymous_variant 0.9 rifampicin
rpoC 766583 p.Gly1072Ser missense_variant 1.0 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 1.0 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766621 c.3252G>A synonymous_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.95 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.94 rifampicin
rpoC 766654 c.3285C>G synonymous_variant 0.94 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.94 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.94 rifampicin
rpoC 766681 c.3312C>T synonymous_variant 0.95 rifampicin
rpoC 766684 c.3315C>G synonymous_variant 0.95 rifampicin
rpoC 766700 c.3331C>T synonymous_variant 0.95 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.95 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.95 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 0.95 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.94 rifampicin
rpoC 766792 c.3423C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766795 c.3426C>T synonymous_variant 1.0 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 1.0 rifampicin
rpoC 766907 c.3538C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766918 c.3549C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 1.0 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 1.0 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 1.0 rifampicin
rpoC 766975 c.3606C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 1.0 rifampicin
rpsL 781709 c.150G>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781721 c.162C>G synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781742 c.183C>T synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781808 c.249C>T synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781841 c.282C>G synonymous_variant 1.0 streptomycin
rpsL 781847 c.288G>A synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>A synonymous_variant 1.0 streptomycin
rpsL 781880 c.321C>G synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800597 c.-212A>G upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 1.0 linezolid
rplC 800609 c.-200G>A upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 1.0 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 1.0 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 1.0 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 1.0 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 1.0 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 1.0 linezolid
rplC 800783 c.-26C>T upstream_gene_variant 1.0 linezolid
rplC 800797 c.-12T>G upstream_gene_variant 1.0 linezolid
rplC 800799 c.-10G>C upstream_gene_variant 1.0 linezolid
rplC 800800 c.-9G>T upstream_gene_variant 1.0 linezolid
rplC 800801 c.-8A>G upstream_gene_variant 1.0 linezolid
rplC 800817 c.9A>C synonymous_variant 1.0 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800877 c.69A>C synonymous_variant 1.0 linezolid
rplC 800907 c.99C>G synonymous_variant 1.0 linezolid
rplC 800913 c.105G>C synonymous_variant 1.0 linezolid
rplC 800916 c.108A>T synonymous_variant 1.0 linezolid
rplC 800922 c.114C>G synonymous_variant 1.0 linezolid
rplC 801276 c.468G>C synonymous_variant 1.0 linezolid
rplC 801297 c.489C>T synonymous_variant 0.92 linezolid Not assoc w R - Interim
rplC 801312 c.504G>C synonymous_variant 1.0 linezolid
rplC 801339 c.531T>G synonymous_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801372 c.564G>A synonymous_variant 1.0 linezolid
rplC 801385 c.577C>T synonymous_variant 1.0 linezolid
rplC 801396 c.588T>C synonymous_variant 1.0 linezolid
rplC 801405 c.597T>C synonymous_variant 1.0 linezolid
fbiC 1303620 c.690C>T synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303644 c.714G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303689 c.759T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303695 c.765T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303704 c.774T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303708 c.778T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303731 c.801A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303732 p.Ser268Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303737 c.807G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303884 c.954T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303890 c.960G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303902 c.972G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303905 c.975G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303911 c.981G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303923 c.993C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303932 c.1002G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303947 c.1017T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303948 p.Gly340Arg missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303956 p.Glu342Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303961 p.Arg344Leu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303969 p.Val347Ile missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303973 p.Gly348Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303980 c.1050G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303998 c.1068T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304001 c.1071C>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304004 c.1074A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304008 c.1078T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304022 c.1092T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304031 c.1101C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304049 c.1119T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304055 p.Asp375Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304058 p.Glu376Asp missense_variant 1.0 pretomanid
delamanid Uncertain significance
clofazimine
fbiC 1304059 c.1129C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304064 c.1134G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304067 c.1137G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304074 p.Ala382Ser missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304079 c.1149A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304091 c.1161C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304092 p.Met388Leu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304112 c.1182G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304120 p.Lys397Arg missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304124 c.1194C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304127 c.1197A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304142 c.1212G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304163 c.1233G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304164 p.Gly412Arg missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304172 c.1242G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304174 p.Val415Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304178 c.1248G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304181 c.1251G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304184 c.1254G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304200 p.Leu424Phe missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304205 c.1275C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304208 c.1278C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304217 p.Asn429Lys missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304546 p.Val539Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304556 c.1626C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304565 c.1635C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304598 c.1668C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304625 c.1695C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304628 c.1698G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304649 c.1719C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304658 c.1728C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304661 c.1731C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304675 p.Gly582Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304679 c.1749G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304691 c.1761G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304703 c.1773C>T synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304715 c.1785G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304724 c.1794A>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304742 c.1812T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304751 c.1821C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304784 c.1854T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304790 c.1860C>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304799 c.1869G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304808 c.1878C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304809 p.Ser627Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304832 c.1902C>T synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304893 p.Gly655Ser missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304901 c.1971C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305078 c.2148A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305088 p.Val720Ile missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305096 c.2166T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305099 c.2169T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305111 c.2181C>T synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1305117 c.2187T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305120 c.2190G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305126 c.2196T>C synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1305150 c.2220C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305154 c.2224T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305159 c.2229G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305162 c.2232C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305165 c.2235G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305186 c.2256C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305192 c.2262C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305195 c.2265T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305204 c.2274C>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305215 p.Ser762Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305219 p.His763Gln missense_variant 1.0 pretomanid
delamanid
clofazimine
sigE 1364802 c.390C>G synonymous_variant 1.0 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 1.0 pyrazinamide
sigE 1364818 c.406_408delCTAinsTTG synonymous_variant 1.0 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 1.0 pyrazinamide
sigE 1364844 c.432C>T synonymous_variant 1.0 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364866 p.Ala152Thr missense_variant 1.0 pyrazinamide
sigE 1364889 c.477A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364898 c.486C>T synonymous_variant 1.0 pyrazinamide
sigE 1364913 c.501C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 1.0 pyrazinamide
sigE 1364943 c.531C>T synonymous_variant 1.0 pyrazinamide
sigE 1364955 c.543G>T synonymous_variant 1.0 pyrazinamide
sigE 1365012 c.600G>A synonymous_variant 1.0 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 1.0 pyrazinamide
sigE 1365019 c.607C>T synonymous_variant 1.0 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 1.0 pyrazinamide
sigE 1365027 c.615C>T synonymous_variant 1.0 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 1.0 pyrazinamide
sigE 1365037 c.625C>T synonymous_variant 1.0 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 1.0 pyrazinamide
sigE 1365054 c.642C>T synonymous_variant 1.0 pyrazinamide
atpE 1461098 c.54C>G synonymous_variant 1.0 bedaquiline
atpE 1461107 c.63C>G synonymous_variant 1.0 bedaquiline
atpE 1461119 c.75T>C synonymous_variant 1.0 bedaquiline
atpE 1461131 c.87T>C synonymous_variant 1.0 bedaquiline
atpE 1461146 c.102G>C synonymous_variant 1.0 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
atpE 1461167 c.123G>T synonymous_variant 1.0 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 1.0 bedaquiline
atpE 1461185 c.141G>A synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.9 bedaquiline
inhA 1673607 c.-595T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673609 c.-593G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673616 c.-586A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673619 c.-583T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674015 c.-187C>A upstream_gene_variant 0.92 isoniazid
ethionamide
inhA 1674018 c.-184G>C upstream_gene_variant 0.92 isoniazid
ethionamide
inhA 1674024 c.-178T>C upstream_gene_variant 0.94 isoniazid
ethionamide
inhA 1674033 c.-169T>C upstream_gene_variant 0.94 isoniazid
ethionamide
inhA 1674037 c.-165C>G upstream_gene_variant 0.94 isoniazid
ethionamide
inhA 1674045 c.-157G>A upstream_gene_variant 0.94 isoniazid
ethionamide
inhA 1674054 c.-148T>C upstream_gene_variant 0.93 isoniazid
ethionamide
inhA 1674060 c.-142A>G upstream_gene_variant 0.93 isoniazid
ethionamide
inhA 1674079 c.-123_-121delCCCinsGCT upstream_gene_variant 0.92 isoniazid
ethionamide
inhA 1674105 c.-97C>T upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674108 c.-94C>T upstream_gene_variant 1.0 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674111 c.-91G>A upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674114 c.-88T>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674117 c.-85C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674123 c.-79T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674129 c.-73C>T upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674132 c.-70T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 1.0 isoniazid
ethionamide
inhA 1674546 c.345T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674561 c.360C>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674570 c.369G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674573 c.372G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674576 c.375T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674579 c.378G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674582 c.381T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674585 c.384T>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674588 c.387G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674594 c.393C>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674601 c.400C>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674609 c.408G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674618 c.417C>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674620 p.Pro140Arg missense_variant 1.0 isoniazid
ethionamide
inhA 1674624 c.423A>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674627 c.426T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674675 c.474C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674703 c.502T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674718 c.517A>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674729 c.528G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674756 c.555T>C synonymous_variant 0.95 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674762 c.561T>C synonymous_variant 0.95 isoniazid
ethionamide
inhA 1674774 c.573A>C synonymous_variant 0.95 isoniazid
ethionamide
inhA 1674777 c.576C>G synonymous_variant 0.95 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 0.95 isoniazid
ethionamide
inhA 1674799 p.Ser200Ala missense_variant 0.94 isoniazid
ethionamide
inhA 1674804 c.603G>A synonymous_variant 0.95 isoniazid
ethionamide
inhA 1674822 c.621C>G synonymous_variant 0.95 isoniazid
ethionamide
inhA 1674852 c.651G>A synonymous_variant 0.95 isoniazid
ethionamide
inhA 1674858 c.657G>A synonymous_variant 0.94 isoniazid
ethionamide
inhA 1674870 c.669T>C synonymous_variant 0.93 isoniazid
ethionamide
inhA 1674879 c.678T>G synonymous_variant 0.93 isoniazid
ethionamide
inhA 1674882 c.681G>C synonymous_variant 0.93 isoniazid
ethionamide
inhA 1674885 c.684C>T synonymous_variant 0.93 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674903 c.702T>C synonymous_variant 0.91 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 1.0 isoniazid
ethionamide
inhA 1674912 c.711G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674957 c.756G>C synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674993 c.792G>C synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674999 c.798C>T synonymous_variant 0.9 isoniazid
ethionamide
inhA 1675002 c.801A>G synonymous_variant 0.9 isoniazid
ethionamide
rpsA 1833554 p.Thr5Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1833589 c.48A>T synonymous_variant 1.0 pyrazinamide
rpsA 1833593 p.Ser18Thr missense_variant 1.0 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833610 c.69C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833718 c.177C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833754 c.213G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833850 c.309C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834024 c.483G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834135 c.594G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834148 c.607C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834174 c.633C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834336 c.795C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834339 c.798C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834369 c.828C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834375 c.834G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834495 c.954G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834615 c.1074C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
tsnR 1853360 c.-246G>A upstream_gene_variant 1.0 linezolid
bacA 2064096 p.Ala211Gly missense_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064099 c.630G>C synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064111 c.618C>G synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064114 c.615T>G synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064117 c.612T>C synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064120 c.609G>C synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064123 c.606T>G synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064129 c.600C>T synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064132 p.Ala199Val missense_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064135 c.594G>A synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064150 c.579T>C synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064155 p.Val192Ile missense_variant 1.0 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
bacA 2064165 c.564T>C synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064192 c.537A>G synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064207 c.522C>T synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064210 c.519A>G synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064219 c.510C>G synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064222 c.507G>A synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin
streptomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
bacA 2064240 p.Gln163Lys missense_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064243 c.486A>C synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064254 p.His159Asp missense_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064258 c.471A>G synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064264 c.465C>G synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064269 c.460A>C synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064296 c.433T>C synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064297 c.432C>T synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2518561 c.447T>C synonymous_variant 1.0 isoniazid
kasA 2518567 c.453G>T synonymous_variant 1.0 isoniazid
kasA 2518573 c.459G>C synonymous_variant 1.0 isoniazid
kasA 2518574 p.Ile154Val missense_variant 1.0 isoniazid
kasA 2518588 c.474T>C synonymous_variant 1.0 isoniazid
kasA 2518591 c.477G>C synonymous_variant 1.0 isoniazid
kasA 2518618 c.504G>C synonymous_variant 1.0 isoniazid
kasA 2518633 c.519G>C synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518645 c.531G>C synonymous_variant 1.0 isoniazid
kasA 2518648 c.534C>T synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518681 c.567C>T synonymous_variant 1.0 isoniazid
kasA 2518684 c.570C>A synonymous_variant 1.0 isoniazid
kasA 2518711 c.597A>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>T synonymous_variant 1.0 isoniazid
kasA 2518735 c.621C>A synonymous_variant 1.0 isoniazid
kasA 2518744 c.630C>T synonymous_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.94 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.94 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.89 isoniazid
kasA 2518789 c.675G>T synonymous_variant 0.88 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.87 isoniazid
kasA 2518798 c.684G>C synonymous_variant 0.87 isoniazid
kasA 2518816 c.702C>T synonymous_variant 0.88 isoniazid
kasA 2518822 c.708C>T synonymous_variant 0.86 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.85 isoniazid
kasA 2518855 c.741C>G synonymous_variant 0.84 isoniazid
kasA 2518856 p.Ile248Leu missense_variant 0.83 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.84 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.8 isoniazid
kasA 2518894 c.780G>A synonymous_variant 0.8 isoniazid
kasA 2518903 c.789C>T synonymous_variant 0.93 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.93 isoniazid
kasA 2518910 c.796C>T synonymous_variant 0.93 isoniazid
kasA 2518939 c.825T>C synonymous_variant 0.86 isoniazid
kasA 2518942 c.828T>C synonymous_variant 0.86 isoniazid
kasA 2518951 c.837G>A synonymous_variant 0.92 isoniazid
kasA 2518960 c.846C>G synonymous_variant 0.92 isoniazid
kasA 2518963 c.849T>C synonymous_variant 0.91 isoniazid
kasA 2518969 c.855T>G synonymous_variant 0.92 isoniazid
kasA 2518978 c.864T>C synonymous_variant 0.91 isoniazid
kasA 2518979 c.865A>C synonymous_variant 0.9 isoniazid
ahpC 2726303 c.111T>C synonymous_variant 1.0 isoniazid
ahpC 2726304 p.Ile38Val missense_variant 1.0 isoniazid
ahpC 2726311 p.Ser40Asn missense_variant 1.0 isoniazid
ahpC 2726315 p.Asp41Glu missense_variant 1.0 isoniazid
ahpC 2726318 p.Glu42Asp missense_variant 1.0 isoniazid
ahpC 2726324 c.132A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726336 c.144G>C synonymous_variant 1.0 isoniazid
ahpC 2726348 c.156T>C synonymous_variant 1.0 isoniazid
ahpC 2726354 c.162G>C synonymous_variant 1.0 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726366 c.174G>C synonymous_variant 1.0 isoniazid
ahpC 2726378 c.186T>G synonymous_variant 1.0 isoniazid
ahpC 2726393 c.201G>C synonymous_variant 1.0 isoniazid
ahpC 2726397 p.Ser69Gly missense_variant 1.0 isoniazid
ahpC 2726408 c.216T>C synonymous_variant 1.0 isoniazid
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
pepQ 2860329 c.90G>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2860332 c.87C>T synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2860345 p.Ser25Thr missense_variant 1.0 bedaquiline
clofazimine
pepQ 2860349 p.Ile24Val missense_variant 1.0 bedaquiline
clofazimine
pepQ 2860364 c.55T>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2860365 c.54G>A synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2860370 p.Ser17Ala missense_variant 1.0 bedaquiline
clofazimine
pepQ 2860375 p.Ala15Gly missense_variant 1.0 bedaquiline
clofazimine
pepQ 2860377 c.42C>T synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2860382 p.Gln13Lys missense_variant 1.0 bedaquiline
clofazimine
pepQ 2860383 c.36A>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2860389 c.30G>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2860392 p.Lys9Asn missense_variant 1.0 bedaquiline
clofazimine
pepQ 2860397 p.Asp8His missense_variant 1.0 bedaquiline
clofazimine
pepQ 2860423 c.-5G>C upstream_gene_variant 1.0 bedaquiline
clofazimine
pepQ 2860434 c.-17_-16delGAinsT upstream_gene_variant 1.0 bedaquiline
clofazimine
Rv2752c 3065430 c.762A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065442 c.750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065451 c.741G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065457 c.735A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065463 c.729T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065469 c.723C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065478 c.714C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065481 c.711T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065484 c.708G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065487 c.705T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065490 c.702A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065493 c.699G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065499 c.693A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065502 p.Asp230Glu missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065508 c.684T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065517 c.673_675delCTCinsTTG synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065532 c.660A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065556 c.636G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065583 c.609G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065594 c.598C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065595 p.Leu199Phe missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065612 p.Thr194Ala missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065625 c.567G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065634 c.558G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065637 c.555A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065640 c.552T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065652 c.540C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065658 p.Pro178Leu missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3065661 c.531A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065666 c.526T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065675 p.Phe173Leu missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066573 c.-382G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066579 c.-388A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066592 c.-401A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066612 c.-421G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066618 c.-427A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066630 c.-439G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066633 c.-442T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066644 c.-453T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066648 c.-457C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066654 c.-463G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066657 c.-466C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066672 c.-481G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066675 c.-485_-484delCGinsGC upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066678 c.-487G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066683 c.-492C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066684 c.-493G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066696 c.-505T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066707 c.-516A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066714 c.-523G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066729 c.-538C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066771 c.-580C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066774 c.-583T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066780 c.-589C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066783 c.-592G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066810 c.-619G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066816 c.-625G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066819 c.-628T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066822 c.-633_-631delGCTinsTCC upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066839 c.-648A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073997 c.475C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074045 c.427C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 1.0 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 1.0 para-aminosalicylic_acid
thyA 3074061 p.Glu137Asp missense_variant 1.0 para-aminosalicylic_acid
thyA 3074091 c.381C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074283 c.189G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074286 c.186T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074297 c.175C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074307 c.165A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074313 c.159A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074334 c.138T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074349 c.123T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074355 c.117G>C synonymous_variant 1.0 para-aminosalicylic_acid
lpqB 3623489 c.1422C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3623492 c.1419T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623510 c.1401C>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623531 p.Gly460Asp missense_variant 0.9 rifampicin
bedaquiline
lpqB 3624023 c.888G>A synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624026 c.885G>A synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624041 p.Glu290Asp missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624071 c.840C>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624276 p.Arg212His missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624323 c.588G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624339 p.Arg191His missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624341 c.570C>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624356 c.555C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624368 c.543C>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624389 c.522C>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624406 c.505C>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3625231 c.-321G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625243 c.-333T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625255 c.-345T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625273 c.-363C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625279 c.-369C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625282 c.-372C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625327 c.-417A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625345 c.-435T>C upstream_gene_variant 0.91 rifampicin
bedaquiline
lpqB 3625366 c.-456C>A upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625426 c.-516G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625432 c.-522G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625489 c.-579A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625497 c.1117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625537 c.-627T>C upstream_gene_variant 0.92 rifampicin
bedaquiline
lpqB 3625543 c.-633G>C upstream_gene_variant 0.92 rifampicin
bedaquiline
mtrB 3625569 c.1045T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625572 p.Thr348Ser missense_variant 0.91 rifampicin
bedaquiline
lpqB 3625579 c.-669A>G upstream_gene_variant 0.92 rifampicin
bedaquiline
lpqB 3625588 c.-678G>A upstream_gene_variant 0.93 rifampicin
bedaquiline
lpqB 3625594 c.-684T>C upstream_gene_variant 0.93 rifampicin
bedaquiline
lpqB 3625602 c.-692T>C upstream_gene_variant 0.92 rifampicin
bedaquiline
lpqB 3625612 c.-702G>T upstream_gene_variant 0.92 rifampicin
bedaquiline
lpqB 3625615 c.-705G>C upstream_gene_variant 0.92 rifampicin
bedaquiline
lpqB 3625624 c.-714C>G upstream_gene_variant 0.93 rifampicin
bedaquiline
lpqB 3625630 c.-720C>G upstream_gene_variant 0.86 rifampicin
bedaquiline
mtrB 3625633 c.981C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625648 c.-738T>C upstream_gene_variant 0.85 rifampicin
bedaquiline
lpqB 3625663 c.-753G>C upstream_gene_variant 0.91 rifampicin
bedaquiline
lpqB 3625684 c.-774G>A upstream_gene_variant 0.92 rifampicin
bedaquiline
lpqB 3625690 c.-780T>C upstream_gene_variant 0.92 rifampicin
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625909 c.-999T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625915 c.699G>A synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625927 c.687T>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625935 p.Ala227Ser missense_variant 1.0 rifampicin Uncertain significance
bedaquiline Uncertain significance
mtrB 3625936 c.678C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625939 c.675G>A synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625945 c.669A>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625951 c.663A>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625959 p.Gly219Ser missense_variant 1.0 rifampicin
bedaquiline
mtrB 3625963 c.651C>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625966 c.648C>A synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625972 c.642G>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625978 c.636T>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625989 p.Thr209Ala missense_variant 1.0 rifampicin
bedaquiline
mtrB 3625993 c.621G>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625999 c.615A>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626006 p.Ser203Asn missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626008 c.606G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626029 c.585A>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626776 c.-163A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626780 c.-167T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626786 c.564A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626792 c.558G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626795 c.-182C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626798 c.-185T>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626866 c.-253T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626885 c.-272A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626890 c.-277T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626912 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626930 c.-317A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626936 c.-323C>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626939 p.Glu137Asp missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626942 c.-329A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626945 c.-332C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626954 c.-341C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626963 c.387G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627182 c.-569T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627187 c.163T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627188 c.-577_-575delTTAinsCTG upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627203 c.-590C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627227 c.123T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
fbiA 3640232 c.-311T>C upstream_gene_variant 1.0 pretomanid
delamanid
clofazimine
fbiA 3640247 c.-296T>G upstream_gene_variant 1.0 pretomanid
delamanid
clofazimine
fbiA 3640260 c.-283T>C upstream_gene_variant 1.0 pretomanid
delamanid
clofazimine
fbiA 3640261 c.-282C>T upstream_gene_variant 1.0 pretomanid
delamanid
clofazimine
fbiA 3640269 c.-274A>C upstream_gene_variant 1.0 pretomanid
delamanid
clofazimine
fbiA 3640282 c.-261C>G upstream_gene_variant 1.0 pretomanid
delamanid
clofazimine
fbiA 3640298 c.-245A>G upstream_gene_variant 1.0 pretomanid
delamanid
clofazimine
fbiA 3640318 c.-225A>T upstream_gene_variant 1.0 pretomanid
delamanid
clofazimine
fbiA 3640365 c.-178C>G upstream_gene_variant 1.0 pretomanid
delamanid
clofazimine
rpoA 3877731 c.777G>T synonymous_variant 1.0 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 1.0 rifampicin
rpoA 3877737 c.771G>T synonymous_variant 1.0 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877746 c.762G>C synonymous_variant 1.0 rifampicin
rpoA 3877752 c.756C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877755 c.753C>A synonymous_variant 1.0 rifampicin
rpoA 3877764 c.744C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877830 c.678C>T synonymous_variant 1.0 rifampicin
rpoA 3877836 c.672A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>G synonymous_variant 1.0 rifampicin
rpoA 3877886 c.622C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877896 c.612G>C synonymous_variant 1.0 rifampicin
rpoA 3877899 p.Ser203Thr missense_variant 1.0 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 1.0 rifampicin
rpoA 3877926 c.582G>C synonymous_variant 1.0 rifampicin
rpoA 3877929 c.579C>T synonymous_variant 1.0 rifampicin
rpoA 3877950 c.558C>T synonymous_variant 1.0 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 1.0 rifampicin
rpoA 3878172 c.336G>C synonymous_variant 1.0 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878202 c.306G>C synonymous_variant 1.0 rifampicin
rpoA 3878211 c.297G>A synonymous_variant 1.0 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 1.0 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 1.0 rifampicin
rpoA 3878262 c.246C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878295 c.213A>G synonymous_variant 1.0 rifampicin
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878742 c.-235G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878785 c.-278T>G upstream_gene_variant 1.0 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878791 c.-284C>T upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878797 c.-290G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878833 c.-326C>T upstream_gene_variant 1.0 rifampicin
rpoA 3878836 c.-330_-329delAGinsCC upstream_gene_variant 1.0 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878909 c.-402A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878920 c.-413C>T upstream_gene_variant 1.0 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878962 c.-455G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878977 c.-470C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878995 c.-488A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3879004 c.-499_-497delAAGinsCGA upstream_gene_variant 1.0 rifampicin
rpoA 3879016 c.-509A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879043 c.-536C>G upstream_gene_variant 1.0 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879100 c.-593G>A upstream_gene_variant 1.0 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 1.0 rifampicin
ddn 3986636 c.-208C>A upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986637 c.-207C>T upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986648 c.-196C>G upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986657 c.-187C>G upstream_gene_variant 1.0 pretomanid
delamanid
clpC1 4038238 p.Thr823Ala missense_variant 0.9 pyrazinamide
clpC1 4038239 c.2466T>C synonymous_variant 0.91 pyrazinamide
clpC1 4038271 p.Pro812Ala missense_variant 0.94 pyrazinamide
clpC1 4038272 c.2433T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.94 pyrazinamide
clpC1 4038308 c.2397G>C synonymous_variant 0.89 pyrazinamide
clpC1 4038314 c.2391T>G synonymous_variant 0.89 pyrazinamide
clpC1 4038335 c.2370C>T synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038344 c.2361G>A synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038350 c.2355C>G synonymous_variant 0.95 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.95 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038383 c.2322G>A synonymous_variant 0.94 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 0.92 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.91 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038407 c.2298G>C synonymous_variant 0.91 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 0.91 pyrazinamide
clpC1 4038436 p.Ala757Ser missense_variant 0.92 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.91 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.91 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.92 pyrazinamide
clpC1 4038519 p.Arg729Gln missense_variant 1.0 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038839 c.1866G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038902 c.1803C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039090 c.1615C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 0.92 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039337 c.1368A>C synonymous_variant 0.91 pyrazinamide
clpC1 4039352 c.1353C>T synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4039391 c.1314T>G synonymous_variant 0.86 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.92 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039442 c.1261_1263delCTAinsTTG synonymous_variant 0.91 pyrazinamide
clpC1 4039448 c.1257A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4039454 c.1251A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039484 c.1221T>G synonymous_variant 0.92 pyrazinamide
clpC1 4039493 c.1212C>T synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4039514 c.1191C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039541 c.1164C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039552 c.1153C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039733 c.972G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039942 c.763C>T synonymous_variant 0.8 pyrazinamide
clpC1 4039946 c.759A>G synonymous_variant 0.82 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.82 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.83 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040033 c.672G>C synonymous_variant 0.93 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.93 pyrazinamide
clpC1 4040048 c.657C>T synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040091 c.613_614delTCinsAG synonymous_variant 1.0 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 1.0 pyrazinamide
glpK 4138403 c.1353G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138409 c.1347G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138418 c.1338T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138424 c.1332T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138429 c.1327T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138451 c.1305T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138456 c.1300C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138459 p.Asp433Asn missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138868 c.888G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138877 c.879A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138880 c.876T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138889 c.867G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138898 c.858T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138910 c.846G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138913 c.843T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138919 c.837C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138922 c.834A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138925 c.831G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138931 c.825G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138934 p.Pro274Ala missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138938 p.Ala273Asp missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138943 c.813T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138946 c.810C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138949 c.807A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138973 c.783T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138982 c.774T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
embC 4238999 c.-864C>G upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239014 c.-849C>G upstream_gene_variant 1.0 ethambutol
embC 4239027 c.-836_-834delATCinsCTG upstream_gene_variant 1.0 ethambutol
embC 4239032 c.-831T>C upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239044 c.-819G>C upstream_gene_variant 1.0 ethambutol
embC 4239059 c.-804G>C upstream_gene_variant 1.0 ethambutol
embC 4239068 c.-795A>G upstream_gene_variant 1.0 ethambutol
embC 4239089 c.-774C>G upstream_gene_variant 1.0 ethambutol
embC 4240123 c.261C>G synonymous_variant 1.0 ethambutol
embC 4240128 p.Gln89Arg missense_variant 1.0 ethambutol
embC 4240150 c.288A>G synonymous_variant 1.0 ethambutol
embC 4240151 p.Ser97Pro missense_variant 1.0 ethambutol
embC 4240777 c.915G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 1.0 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240795 c.933C>G synonymous_variant 0.92 ethambutol
embC 4240801 c.939C>T synonymous_variant 0.92 ethambutol
embC 4240831 c.969T>C synonymous_variant 0.91 ethambutol
embC 4241039 p.Asp393Asn missense_variant 1.0 ethambutol
embC 4241050 c.1188T>G synonymous_variant 1.0 ethambutol
embC 4241056 c.1194C>G synonymous_variant 1.0 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.93 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.93 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embC 4241153 p.Ile431Leu missense_variant 0.91 ethambutol
embC 4241161 c.1299C>G synonymous_variant 0.91 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 0.91 ethambutol
embC 4241167 c.1305C>G synonymous_variant 0.9 ethambutol
embC 4241689 c.1827G>C synonymous_variant 0.92 ethambutol
embC 4241692 c.1830C>G synonymous_variant 0.92 ethambutol
embC 4241695 c.1833T>G synonymous_variant 0.92 ethambutol
embC 4241704 c.1842C>G synonymous_variant 0.92 ethambutol
embC 4241707 c.1845G>C synonymous_variant 0.92 ethambutol
embC 4241710 c.1848G>A synonymous_variant 0.92 ethambutol
embC 4241713 c.1851G>C synonymous_variant 0.93 ethambutol
embC 4241719 c.1857G>C synonymous_variant 0.93 ethambutol
embC 4241728 c.1866C>T synonymous_variant 0.93 ethambutol
embA 4244603 c.1371G>A synonymous_variant 0.92 ethambutol
embA 4244612 c.1380C>G synonymous_variant 0.91 ethambutol
embA 4244615 c.1383G>A synonymous_variant 0.91 ethambutol Not assoc w R - Interim
embA 4244616 p.Ala462Ser missense_variant 0.91 ethambutol
embA 4244619 c.1387T>C synonymous_variant 0.91 ethambutol
embA 4244822 c.1590G>A synonymous_variant 0.83 ethambutol
embA 4244823 p.Val531Met missense_variant 0.83 ethambutol
embA 4244856 p.Ala542Pro missense_variant 0.92 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.8 ethambutol
embA 4245206 c.1974A>C synonymous_variant 1.0 ethambutol
embA 4245207 c.1975T>C synonymous_variant 1.0 ethambutol
embA 4245215 c.1983A>C synonymous_variant 1.0 ethambutol
embA 4245224 c.1992T>C synonymous_variant 1.0 ethambutol
embA 4245248 c.2016G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245257 c.2025A>G synonymous_variant 1.0 ethambutol
embA 4245263 c.2031A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245662 c.-852G>C upstream_gene_variant 1.0 ethambutol
embA 4245674 c.2442A>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245677 c.-837G>C upstream_gene_variant 1.0 ethambutol
embB 4245683 c.-831C>T upstream_gene_variant 1.0 ethambutol
embA 4245693 p.Ile821Val missense_variant 1.0 ethambutol
embA 4245942 p.Arg904Gly missense_variant 1.0 ethambutol
embB 4245953 c.-561A>G upstream_gene_variant 1.0 ethambutol
embB 4245956 c.-558G>C upstream_gene_variant 1.0 ethambutol
embA 4245965 c.2733A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245968 c.-546T>C upstream_gene_variant 1.0 ethambutol
embA 4245978 p.Ile916Leu missense_variant 1.0 ethambutol
embB 4245983 c.-531A>G upstream_gene_variant 1.0 ethambutol
embB 4245992 c.-522C>G upstream_gene_variant 1.0 ethambutol
embB 4246004 c.-510T>C upstream_gene_variant 1.0 ethambutol
embB 4246005 c.-509C>T upstream_gene_variant 1.0 ethambutol
embB 4246013 c.-501T>C upstream_gene_variant 1.0 ethambutol
embA 4246020 p.Ala930Thr missense_variant 1.0 ethambutol
embA 4246028 c.2796G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246070 c.-444G>C upstream_gene_variant 1.0 ethambutol
embB 4246082 c.-432T>C upstream_gene_variant 1.0 ethambutol
embB 4246109 c.-405C>G upstream_gene_variant 1.0 ethambutol
embB 4246115 c.-399T>C upstream_gene_variant 1.0 ethambutol
embA 4246128 p.Ser966Thr missense_variant 1.0 ethambutol
embA 4246138 p.Arg969Gln missense_variant 1.0 ethambutol
embB 4246140 c.-374T>C upstream_gene_variant 1.0 ethambutol
embB 4246148 c.-366G>C upstream_gene_variant 1.0 ethambutol
embB 4246151 c.-363A>C upstream_gene_variant 1.0 ethambutol
embA 4246152 p.Ala974Arg missense_variant 1.0 ethambutol
embA 4246235 c.3003G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246244 c.-270G>A upstream_gene_variant 1.0 ethambutol
embA 4246254 p.Leu1008Met missense_variant 1.0 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 1.0 ethambutol
embA 4246265 c.3033C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246268 c.-246G>A upstream_gene_variant 1.0 ethambutol
embA 4246279 p.Ala1016Val missense_variant 1.0 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 1.0 ethambutol
embB 4246307 c.-207G>C upstream_gene_variant 1.0 ethambutol
embB 4246316 c.-198T>C upstream_gene_variant 1.0 ethambutol
embB 4246346 c.-168C>G upstream_gene_variant 1.0 ethambutol
embB 4247089 c.576G>C synonymous_variant 1.0 ethambutol
embB 4247095 c.582G>A synonymous_variant 1.0 ethambutol
embB 4247104 c.591G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247113 c.600G>A synonymous_variant 1.0 ethambutol
embB 4247114 p.Ala201Lys missense_variant 1.0 ethambutol
embB 4247117 p.Val202Leu missense_variant 1.0 ethambutol
embB 4247137 c.624C>G synonymous_variant 1.0 ethambutol
embB 4247140 c.627G>C synonymous_variant 1.0 ethambutol
embB 4247150 p.Arg213Thr missense_variant 1.0 ethambutol
embB 4247155 c.642G>A synonymous_variant 0.9 ethambutol
embB 4247470 c.957T>C synonymous_variant 1.0 ethambutol
embB 4247497 c.984T>C synonymous_variant 1.0 ethambutol
embB 4247500 c.987C>G synonymous_variant 1.0 ethambutol
embB 4247512 c.999T>C synonymous_variant 1.0 ethambutol
embB 4247554 c.1041T>C synonymous_variant 1.0 ethambutol
embB 4247555 p.Leu348Ile missense_variant 1.0 ethambutol
embB 4247566 c.1053C>G synonymous_variant 1.0 ethambutol
embB 4247579 p.Ala356Phe missense_variant 1.0 ethambutol
embB 4247590 c.1077A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247608 c.1095G>C synonymous_variant 1.0 ethambutol
embB 4247611 c.1098G>C synonymous_variant 1.0 ethambutol
embB 4247632 c.1119C>G synonymous_variant 1.0 ethambutol
embB 4247645 p.Glu378Thr missense_variant 1.0 ethambutol
embB 4247648 p.Ala379Ser missense_variant 1.0 ethambutol
embB 4247657 p.Pro382Ala missense_variant 1.0 ethambutol
embB 4247671 c.1158G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247679 p.Met389Thr missense_variant 1.0 ethambutol
embB 4247684 c.1171T>C synonymous_variant 1.0 ethambutol
embB 4247722 c.1209G>C synonymous_variant 1.0 ethambutol
embB 4247725 c.1212G>C synonymous_variant 1.0 ethambutol
embB 4247728 c.1215G>A synonymous_variant 1.0 ethambutol
embB 4247743 c.1230C>G synonymous_variant 1.0 ethambutol
embB 4247761 c.1248T>C synonymous_variant 0.93 ethambutol
embB 4247779 c.1266C>G synonymous_variant 0.91 ethambutol Not assoc w R - Interim
embB 4247785 c.1272G>C synonymous_variant 0.91 ethambutol
embB 4247800 c.1287A>C synonymous_variant 0.91 ethambutol
embB 4247830 c.1317A>G synonymous_variant 0.9 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>G synonymous_variant 0.91 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 0.91 ethambutol Not assoc w R - Interim
embB 4247858 c.1345C>T synonymous_variant 0.81 ethambutol
embB 4247899 p.Met462Ile missense_variant 0.8 ethambutol
embB 4247911 p.Leu466Phe missense_variant 0.79 ethambutol
embB 4247915 p.Arg468Lys missense_variant 0.79 ethambutol
embB 4247920 c.1407T>C synonymous_variant 0.79 ethambutol
embB 4247923 c.1410T>C synonymous_variant 0.79 ethambutol
embB 4247932 c.1419C>G synonymous_variant 0.79 ethambutol
embB 4247948 p.Val479Leu missense_variant 0.8 ethambutol Uncertain significance
embB 4247975 p.Val488Ile missense_variant 0.83 ethambutol Uncertain significance
embB 4247989 c.1476G>C synonymous_variant 0.83 ethambutol
embB 4248001 c.1488C>T synonymous_variant 0.87 ethambutol Not assoc w R - Interim
embB 4248007 c.1494C>G synonymous_variant 0.87 ethambutol
embB 4248042 p.Ala510Gly missense_variant 1.0 ethambutol
embB 4248052 c.1539G>T synonymous_variant 1.0 ethambutol
embB 4248055 c.1542G>C synonymous_variant 1.0 ethambutol
embB 4248058 c.1545C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248061 c.1548G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248064 c.1551G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 1.0 ethambutol
embB 4248094 c.1581C>T synonymous_variant 1.0 ethambutol
embB 4248130 c.1617G>C synonymous_variant 1.0 ethambutol
embB 4248142 c.1629T>C synonymous_variant 1.0 ethambutol
embB 4248143 c.1630T>C synonymous_variant 1.0 ethambutol
embB 4248154 c.1641G>T synonymous_variant 1.0 ethambutol
embB 4248157 c.1644A>T synonymous_variant 1.0 ethambutol
embB 4248163 c.1650G>A synonymous_variant 1.0 ethambutol
embB 4248169 c.1656C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248175 c.1662G>A synonymous_variant 1.0 ethambutol
embB 4248178 c.1665C>T synonymous_variant 1.0 ethambutol
embB 4248206 p.Ser565Gly missense_variant 1.0 ethambutol Uncertain significance
embB 4248214 c.1701C>G synonymous_variant 1.0 ethambutol
embB 4248217 c.1704C>G synonymous_variant 1.0 ethambutol
embB 4248220 c.1707A>G synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embB 4248233 c.1720C>T synonymous_variant 1.0 ethambutol
embB 4248252 p.Gly580Ala missense_variant 1.0 ethambutol
embB 4248266 c.1753C>T synonymous_variant 1.0 ethambutol
embB 4248277 c.1764G>C synonymous_variant 1.0 ethambutol
embB 4248280 c.1767C>G synonymous_variant 1.0 ethambutol
embB 4248316 c.1803C>G synonymous_variant 1.0 ethambutol
embB 4248319 c.1806A>G synonymous_variant 1.0 ethambutol
embB 4248358 c.1845C>G synonymous_variant 1.0 ethambutol
embB 4248361 c.1848A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248379 c.1866G>A synonymous_variant 1.0 ethambutol
embB 4248407 p.Leu632Val missense_variant 1.0 ethambutol
embB 4248412 p.Phe633Leu missense_variant 1.0 ethambutol
embB 4248416 p.Leu635Met missense_variant 1.0 ethambutol
embB 4248424 c.1911G>A synonymous_variant 1.0 ethambutol
embB 4248430 c.1917T>C synonymous_variant 1.0 ethambutol
embB 4248448 c.1935C>T synonymous_variant 1.0 ethambutol
embB 4248457 c.1944T>C synonymous_variant 1.0 ethambutol
embB 4248472 c.1959T>C synonymous_variant 1.0 ethambutol
embB 4249417 c.2904A>G synonymous_variant 1.0 ethambutol
embB 4249474 c.2961C>T synonymous_variant 1.0 ethambutol
embB 4249486 c.2973T>G synonymous_variant 1.0 ethambutol
embB 4249487 c.2974_2976delTTGinsCTC synonymous_variant 1.0 ethambutol
embB 4249492 c.2979C>G synonymous_variant 1.0 ethambutol
embB 4249501 c.2988C>T synonymous_variant 1.0 ethambutol
embB 4249627 c.3114G>C synonymous_variant 1.0 ethambutol
embB 4249640 c.3127T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249648 c.3135G>C synonymous_variant 1.0 ethambutol
embB 4249654 c.3141C>T synonymous_variant 1.0 ethambutol
embB 4249657 c.3144C>G synonymous_variant 1.0 ethambutol
embB 4249663 c.3150C>G synonymous_variant 1.0 ethambutol
embB 4249666 c.3153C>T synonymous_variant 1.0 ethambutol
embB 4249669 c.3156C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249675 c.3162C>G synonymous_variant 1.0 ethambutol
embB 4249693 c.3180T>C synonymous_variant 1.0 ethambutol
embB 4249699 c.3186T>A synonymous_variant 1.0 ethambutol
embB 4249702 c.3189C>A synonymous_variant 1.0 ethambutol
embB 4249703 c.3190C>T synonymous_variant 1.0 ethambutol
embB 4249711 c.3198G>A synonymous_variant 1.0 ethambutol
aftB 4267529 c.1308T>C synonymous_variant 1.0 ethambutol
aftB 4267535 c.1302A>G synonymous_variant 1.0 ethambutol
aftB 4267556 c.1281G>C synonymous_variant 1.0 ethambutol
aftB 4267574 c.1263G>C synonymous_variant 1.0 ethambutol
aftB 4267580 c.1257G>A synonymous_variant 1.0 ethambutol
aftB 4267592 c.1245C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim