TB-Profiler result

Run: ERR2512770
Summary

Run ID: ERR2512770

Sample name:

Date: 2025-09-15T16:21:21.110140

Number of reads: 1571137

Percentage reads mapped: 63.12

Median coverage: 45.0

Strain: lineage4.2.1

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 100.0
lineage4.2 Euro-American None 100.0
lineage4.2.1 Euro-American (TUR) None 100.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 660 c.660G>C synonymous_variant 0.16 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>C synonymous_variant 0.19 isoniazid Uncertain significance
dnaA 666 c.666C>G synonymous_variant 0.16 isoniazid Uncertain significance
dnaA 678 c.678A>G synonymous_variant 0.16 isoniazid Not assoc w R - Interim
dnaA 682 c.682_684delTTGinsCTC synonymous_variant 0.17 isoniazid Uncertain significance
dnaA 687 c.687C>T synonymous_variant 0.19 isoniazid Uncertain significance
dnaA 693 c.693A>C synonymous_variant 0.23 isoniazid Uncertain significance
dnaA 705 c.705A>G synonymous_variant 0.26 isoniazid Uncertain significance
dnaA 708 c.708T>C synonymous_variant 0.27 isoniazid Uncertain significance
dnaA 714 c.714C>T synonymous_variant 0.31 isoniazid Uncertain significance
dnaA 720 c.720G>A synonymous_variant 0.33 isoniazid Uncertain significance
dnaA 741 c.741T>C synonymous_variant 0.29 isoniazid Not assoc w R - Interim
dnaA 747 c.747G>T synonymous_variant 0.26 isoniazid Uncertain significance
dnaA 748 c.748_750delCTCinsTTG synonymous_variant 0.25 isoniazid Uncertain significance
dnaA 763 p.Lys255Arg missense_variant 0.26 isoniazid Uncertain significance
dnaA 771 c.771A>G synonymous_variant 0.25 isoniazid Uncertain significance
dnaA 793 p.Val265Ile missense_variant 0.2 isoniazid Uncertain significance
dnaA 801 c.801G>T synonymous_variant 0.2 isoniazid Uncertain significance
dnaA 804 c.804G>C synonymous_variant 0.2 isoniazid Uncertain significance
dnaA 805 c.805_807delTTGinsCTC synonymous_variant 0.2 isoniazid Uncertain significance
dnaA 822 c.822A>G synonymous_variant 0.24 isoniazid Uncertain significance
dnaA 828 c.828T>C synonymous_variant 0.23 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 0.17 isoniazid Uncertain significance
dnaA 840 c.840G>A synonymous_variant 0.17 isoniazid Uncertain significance
dnaA 846 c.846T>C synonymous_variant 0.16 isoniazid Uncertain significance
dnaA 849 c.849A>G synonymous_variant 0.16 isoniazid Uncertain significance
dnaA 852 c.852G>A synonymous_variant 0.16 isoniazid Not assoc w R - Interim
dnaA 885 c.885T>C synonymous_variant 0.18 isoniazid Uncertain significance
dnaA 888 c.888C>G synonymous_variant 0.18 isoniazid Uncertain significance
dnaA 897 c.897A>G synonymous_variant 0.18 isoniazid Uncertain significance
dnaA 903 c.903C>G synonymous_variant 0.17 isoniazid Not assoc w R - Interim
dnaA 909 c.909A>C synonymous_variant 0.17 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 0.17 isoniazid Uncertain significance
dnaA 918 c.918C>G synonymous_variant 0.17 isoniazid Uncertain significance
dnaA 929 p.Gln310Arg missense_variant 0.13 isoniazid Uncertain significance
gyrB 6346 c.1107C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6676 c.-626T>G upstream_gene_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6703 c.-599G>C upstream_gene_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6706 c.-596G>A upstream_gene_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6709 c.-593A>G upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6712 c.-590G>C upstream_gene_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6727 c.-575G>T upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6739 c.-563C>T upstream_gene_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6745 c.1506T>C synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6754 c.-548C>T upstream_gene_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6763 c.1524G>C synonymous_variant 0.14 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 0.15 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrB 7060 c.1821T>C synonymous_variant 0.14 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7093 c.1854T>C synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7100 c.1861T>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7123 c.-179C>G upstream_gene_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 7126 c.1887G>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7129 c.-173T>G upstream_gene_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7132 c.-170T>C upstream_gene_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7135 c.-167G>A upstream_gene_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7136 c.-166T>C upstream_gene_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7141 c.-161T>G upstream_gene_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7144 c.-158A>G upstream_gene_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7150 c.-152G>A upstream_gene_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 7153 c.1914G>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7168 c.-134C>G upstream_gene_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7178 c.-124T>C upstream_gene_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 7186 c.1947C>G synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7511 c.210C>T synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7523 c.222C>G synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>A synonymous_variant 0.24 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7532 c.231T>C synonymous_variant 0.13 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.14 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7553 c.252C>T synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7559 c.258G>C synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 0.14 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8897 c.1596T>C synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8942 c.1641G>T synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8945 c.1644G>C synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8946 c.1645T>C synonymous_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8957 c.1656C>T synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Lys missense_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8978 c.1677C>T synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8990 c.1689C>G synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8993 c.1692C>T synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8996 c.1695T>C synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8998 p.Leu566Trp missense_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9018 p.Gln573Lys missense_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>C synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9026 c.1725G>C synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9029 c.1728T>C synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9035 c.1734G>C synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
gyrA 9044 c.1743C>G synonymous_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9047 c.1746C>T synonymous_variant 0.13 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
Rv0010c 13781 c.-223C>G upstream_gene_variant 1.0 isoniazid Uncertain significance
fgd1 491247 c.465C>T synonymous_variant 0.94 clofazimine Not assoc w R - Interim
delamanid Not assoc w R - Interim
pretomanid Uncertain significance
ccsA 620328 c.438G>C synonymous_variant 0.15 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620338 p.Thr150Ala missense_variant 0.17 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620349 c.459A>C synonymous_variant 0.16 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620354 p.Trp155Tyr missense_variant 0.15 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620362 p.Ala158Thr missense_variant 0.19 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620365 p.Asn159Tyr missense_variant 0.19 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620388 c.498A>C synonymous_variant 0.23 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620397 c.507C>G synonymous_variant 0.21 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620412 c.522T>C synonymous_variant 0.14 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620415 c.525T>C synonymous_variant 0.15 amikacin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620421 c.531G>C synonymous_variant 0.14 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620430 c.540C>T synonymous_variant 0.15 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620439 c.549T>G synonymous_variant 0.13 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
nusG 734421 c.168A>C synonymous_variant 0.14 rifampicin Uncertain significance
nusG 734445 c.192C>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
nusG 734452 p.Glu67Gln missense_variant 0.19 rifampicin Uncertain significance
nusG 734460 c.207G>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
nusG 734497 p.Val82Ile missense_variant 0.22 rifampicin Uncertain significance
nusG 734532 c.279A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
nusG 734535 c.282C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
nusG 734538 c.285C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>G synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760274 p.Glu156Asp missense_variant 0.18 rifampicin Uncertain significance
rpoB 760276 p.Lys157Met missense_variant 0.18 rifampicin Uncertain significance
rpoB 760283 c.477G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 760376 p.Asp190Glu missense_variant 0.16 rifampicin Uncertain significance
rpoB 760382 c.576G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 760388 c.582C>T synonymous_variant 0.22 rifampicin Uncertain significance
rpoB 760400 c.594G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoB 760407 p.Ser201Gly missense_variant 0.21 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760418 c.612G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760460 c.654G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.24 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760541 c.735G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 0.16 rifampicin Uncertain significance
rpoB 760567 p.Ser254Trp missense_variant 0.16 rifampicin Uncertain significance
rpoB 760568 c.762_763insGC frameshift_variant 0.16 rifampicin Uncertain significance
rpoB 760571 c.765G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 760588 p.Thr261Ile missense_variant 0.22 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.27 rifampicin Uncertain significance
rpoB 760595 c.789C>T synonymous_variant 0.26 rifampicin Uncertain significance
rpoB 760596 p.Thr264Pro missense_variant 0.28 rifampicin Uncertain significance
rpoB 760608 c.802C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760611 c.805T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 760668 p.Thr288Ala missense_variant 0.31 rifampicin Uncertain significance
rpoB 760674 c.868T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 760703 c.897C>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 760721 c.915C>G synonymous_variant 0.23 rifampicin Uncertain significance
rpoB 760727 c.921C>G synonymous_variant 0.18 rifampicin Uncertain significance
rpoB 760730 c.924T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760817 c.1011A>G synonymous_variant 0.21 rifampicin Uncertain significance
rpoB 760820 c.1014T>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoB 760826 c.1020C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760858 p.Val351Ala missense_variant 0.28 rifampicin Uncertain significance
rpoB 760862 c.1056G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760865 c.1059C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760886 p.Glu360Asp missense_variant 0.28 rifampicin Uncertain significance
rpoB 760887 p.Thr361Val missense_variant 0.28 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760928 c.1122G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 760943 c.1137C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.16 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>A synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.34 rifampicin Uncertain significance
rpoB 761102 c.1296A>G synonymous_variant 0.31 rifampicin Uncertain significance
rpoB 761132 c.1326G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 761171 c.1365C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 761178 p.Ser458Thr missense_variant 0.31 rifampicin Uncertain significance
rpoB 761186 p.Glu460Asp missense_variant 0.29 rifampicin Uncertain significance
rpoB 761189 c.1383T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761219 c.1413G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761303 c.1497G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 761564 c.1758G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761612 c.1806G>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 761948 c.2142G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>A synonymous_variant 0.2 rifampicin Uncertain significance
rpoB 761955 p.Ile717Val missense_variant 0.2 rifampicin Uncertain significance
rpoB 761969 c.2163G>A synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 762038 c.2232C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 762056 c.2250G>A synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.19 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.2 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 762134 c.2328C>A synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 762137 c.2331C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 762143 c.2337T>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 762149 c.2343G>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 762194 c.2388G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 762275 c.2469C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762296 c.2490G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762323 c.2517C>A synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 762398 c.-972T>C upstream_gene_variant 0.14 rifampicin Uncertain significance
rpoB 762410 c.2604T>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762449 c.2643C>A synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.22 rifampicin Uncertain significance
rpoB 762510 p.Ala902Pro missense_variant 0.23 rifampicin Uncertain significance
rpoB 762515 c.2709C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 762533 c.-837T>C upstream_gene_variant 0.15 rifampicin Uncertain significance
rpoC 762536 c.-834T>C upstream_gene_variant 0.15 rifampicin Uncertain significance
rpoC 762537 c.-833T>C upstream_gene_variant 0.15 rifampicin Uncertain significance
rpoC 762551 c.-819C>T upstream_gene_variant 0.14 rifampicin Uncertain significance
rpoB 762857 c.3051C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762866 c.3060C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 0.27 rifampicin Uncertain significance
rpoB 762894 c.3088C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762899 c.3093G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762917 c.3111C>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 763082 c.3276C>T synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 763088 c.3282C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 763145 c.3339G>A synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 763157 c.3351G>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 763172 c.3366G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 763184 c.3378C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 763414 c.45T>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763415 p.Thr16Ser missense_variant 0.19 rifampicin Uncertain significance
rpoC 763423 p.Glu18Asp missense_variant 0.21 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCGA synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 763433 p.Gln22Asn missense_variant 0.19 rifampicin Uncertain significance
rpoC 763443 p.Tyr25Phe missense_variant 0.21 rifampicin Uncertain significance
rpoC 763450 c.81G>A synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 763657 c.288G>A synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 763702 c.333C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 763711 c.342G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 763714 c.345G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 763732 c.363C>A synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 764040 p.Ser224Thr missense_variant 0.18 rifampicin Uncertain significance
rpoC 764044 c.675T>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 764054 c.685C>T synonymous_variant 0.23 rifampicin Uncertain significance
rpoC 764059 c.690G>T synonymous_variant 0.23 rifampicin Uncertain significance
rpoC 764095 c.726C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764098 c.729A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764110 c.741C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764143 c.774G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764147 p.Ser260Ala missense_variant 0.32 rifampicin Uncertain significance
rpoC 764150 p.Ile261Val missense_variant 0.29 rifampicin Uncertain significance
rpoC 764165 p.Glu266Gln missense_variant 0.29 rifampicin Uncertain significance
rpoC 764176 c.807C>T synonymous_variant 0.28 rifampicin Uncertain significance
rpoC 764177 p.Ile270Leu missense_variant 0.23 rifampicin Uncertain significance
rpoC 764182 c.813C>T synonymous_variant 0.23 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Asn missense_variant 0.25 rifampicin Uncertain significance
rpoC 764203 c.834G>C synonymous_variant 0.29 rifampicin Uncertain significance
rpoC 764206 p.Asp279Glu missense_variant 0.27 rifampicin Uncertain significance
rpoC 764207 p.Val280Thr missense_variant 0.29 rifampicin Uncertain significance
rpoC 764215 c.846A>C synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 764217 p.Asn283Ser missense_variant 0.26 rifampicin Uncertain significance
rpoC 764365 c.996C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764428 c.1059G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.29 rifampicin Uncertain significance
rpoC 764458 c.1089G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764470 c.1101C>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764534 c.1165C>A synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764542 c.1173C>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764545 c.1176C>A synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764560 c.1191T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764692 c.1323C>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.39 rifampicin Not assoc w R
rpoC 764810 p.Pro481Ala missense_variant 0.38 rifampicin Uncertain significance
rpoC 764815 c.1446A>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 764912 p.Met515Gln missense_variant 0.26 rifampicin Uncertain significance
rpoC 764932 c.1563C>A synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579_1581delTTGinsCTC synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 765343 c.1974G>A synonymous_variant 0.23 rifampicin Uncertain significance
rpoC 765352 c.1983G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 765356 p.Met663Val missense_variant 0.22 rifampicin Uncertain significance
rpoC 765370 c.2001G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 765379 c.2010G>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 765382 c.2013G>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 0.22 rifampicin Uncertain significance
rpoC 765403 c.2034G>C synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 765405 p.Leu679His missense_variant 0.27 rifampicin Uncertain significance
rpoC 765409 c.2040T>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 765421 c.2052C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 765449 p.Ala694Ser missense_variant 0.19 rifampicin Uncertain significance
rpoC 765469 c.2100G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>G synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 765875 p.Val836Ile missense_variant 0.18 rifampicin Uncertain significance
rpoC 765886 c.2517C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765907 c.2538G>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765910 c.2541G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 767044 c.3675G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 767080 c.3711G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 767107 c.3738C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 767125 c.3756G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 767149 c.3780C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 767179 c.3810C>T synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 767180 p.Ala1271Ser missense_variant 0.27 rifampicin Uncertain significance
rpoC 767191 c.3822C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 767203 c.3834C>G synonymous_variant 0.23 rifampicin Uncertain significance
rpoC 767206 c.3837C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 767221 c.3852C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781595 c.36T>C synonymous_variant 0.16 streptomycin Uncertain significance
rpsL 781608 p.Ser17Gly missense_variant 0.16 streptomycin Uncertain significance
rpsL 781628 c.69T>C synonymous_variant 0.18 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781670 c.111G>C synonymous_variant 0.17 streptomycin Uncertain significance
rpsL 781706 c.147T>C synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781715 c.156T>G synonymous_variant 0.16 streptomycin Uncertain significance
rpsL 781721 c.162C>T synonymous_variant 0.14 streptomycin Uncertain significance
rpsL 781725 p.Lys56Arg missense_variant 0.15 streptomycin Uncertain significance
rpsL 781728 c.169T>C synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781733 c.174G>C synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781736 c.177T>C synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781737 p.Gln60Ala missense_variant 0.14 streptomycin Uncertain significance
rpsL 781742 c.183C>G synonymous_variant 0.14 streptomycin Uncertain significance
rpsL 781751 c.192G>C synonymous_variant 0.14 streptomycin Uncertain significance
rpsL 781760 c.201T>C synonymous_variant 0.14 streptomycin Uncertain significance
rpsL 781763 c.204C>G synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781766 c.207C>T synonymous_variant 0.14 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>T synonymous_variant 0.18 streptomycin Not assoc w R - Interim
rpsL 781802 c.243G>C synonymous_variant 0.32 streptomycin Uncertain significance
rpsL 781814 c.255C>T synonymous_variant 0.33 streptomycin Uncertain significance
rpsL 781817 c.258G>T synonymous_variant 0.35 streptomycin Uncertain significance
rpsL 781829 c.270G>C synonymous_variant 0.31 streptomycin Uncertain significance
rpsL 781832 c.273T>C synonymous_variant 0.33 streptomycin Uncertain significance
rpsL 781859 c.300T>C synonymous_variant 0.42 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 0.38 streptomycin Uncertain significance
rpsL 781871 c.312G>C synonymous_variant 0.38 streptomycin Uncertain significance
rpsL 781877 c.318T>A synonymous_variant 0.37 streptomycin Uncertain significance
rpsL 781892 c.333A>G synonymous_variant 0.36 streptomycin Uncertain significance
rpsL 781898 c.339A>T synonymous_variant 0.36 streptomycin Uncertain significance
rpsL 781907 c.348T>C synonymous_variant 0.36 streptomycin Uncertain significance
rpsL 781916 c.357T>C synonymous_variant 0.34 streptomycin Uncertain significance
rpsL 781929 p.Gly124Ser missense_variant 0.27 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.26 streptomycin Uncertain significance
rplC 800204 c.-605T>C upstream_gene_variant 1.0 linezolid Uncertain significance
atpE 1461132 p.Val30Ile missense_variant 0.31 bedaquiline Uncertain significance
atpE 1461146 c.102G>T synonymous_variant 0.29 bedaquiline Uncertain significance
atpE 1461149 c.105T>G synonymous_variant 0.28 bedaquiline Uncertain significance
atpE 1461161 c.117C>G synonymous_variant 0.28 bedaquiline Uncertain significance
atpE 1461164 c.120C>T synonymous_variant 0.27 bedaquiline Uncertain significance
atpE 1461167 c.123G>T synonymous_variant 0.26 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.26 bedaquiline Uncertain significance
atpE 1461179 c.135G>T synonymous_variant 0.24 bedaquiline Uncertain significance
atpE 1461182 c.138A>G synonymous_variant 0.23 bedaquiline Uncertain significance
atpE 1461185 c.141G>C synonymous_variant 0.23 bedaquiline Uncertain significance
atpE 1461197 c.153A>C synonymous_variant 0.22 bedaquiline Uncertain significance
atpE 1461219 c.175T>C synonymous_variant 0.2 bedaquiline Uncertain significance
rrs 1471615 n.-231C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.3 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.33 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.28 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.31 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.58 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.58 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.44 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472032 n.187G>A non_coding_transcript_exon_variant 0.44 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.44 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.44 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.41 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.41 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.41 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472043 n.198T>A non_coding_transcript_exon_variant 0.41 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472050 n.205G>C non_coding_transcript_exon_variant 0.41 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.41 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.44 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.53 amikacin Not assoc w R
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.53 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.53 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.47 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.67 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.81 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.83 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.82 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.77 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.83 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472846 n.1001C>T non_coding_transcript_exon_variant 0.5 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472847 n.1002G>A non_coding_transcript_exon_variant 0.5 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472848 n.1003T>C non_coding_transcript_exon_variant 0.53 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472860 n.1015C>T non_coding_transcript_exon_variant 0.58 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472861 n.1016G>A non_coding_transcript_exon_variant 0.58 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.75 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.82 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.82 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.82 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.81 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.81 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.81 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.81 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Not assoc w R
streptomycin Uncertain significance
rrs 1473082 n.1237G>A non_coding_transcript_exon_variant 0.73 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.7 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 0.67 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.8 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.67 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.67 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.77 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.62 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.76 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473129 n.1284C>T non_coding_transcript_exon_variant 0.59 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.58 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.51 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.53 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.53 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475760 n.2105_2106delGC non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475765 n.2108A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.59 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.65 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.42 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476665 n.3008T>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833547 c.6G>A synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1833589 c.48A>C synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1833595 c.54T>G synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1833596 p.Ser19Ala missense_variant 0.18 pyrazinamide Uncertain significance
rpsA 1833604 c.63C>T synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1833616 c.75A>T synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1833619 c.78A>C synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1833664 c.123C>G synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1833676 c.135A>G synonymous_variant 0.28 pyrazinamide Uncertain significance
rpsA 1833679 c.138G>T synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1833685 c.144G>C synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1833691 c.150G>A synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1833694 c.153G>T synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1833697 c.156C>T synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1833700 c.159C>T synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1833709 c.168C>T synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1833724 c.183C>T synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1833727 c.186G>C synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1833733 c.192C>G synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1833734 p.Ala65Ser missense_variant 0.2 pyrazinamide Uncertain significance
rpsA 1833742 c.201A>G synonymous_variant 0.24 pyrazinamide Uncertain significance
rpsA 1833745 c.204G>C synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1833748 c.207C>G synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1833760 c.219C>T synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1833790 c.249T>C synonymous_variant 0.31 pyrazinamide Uncertain significance
rpsA 1833802 c.261A>G synonymous_variant 0.28 pyrazinamide Uncertain significance
rpsA 1833811 c.270G>T synonymous_variant 0.32 pyrazinamide Uncertain significance
rpsA 1833823 c.282G>A synonymous_variant 0.33 pyrazinamide Uncertain significance
rpsA 1833832 c.291G>A synonymous_variant 0.32 pyrazinamide Uncertain significance
rpsA 1833838 c.297G>C synonymous_variant 0.33 pyrazinamide Uncertain significance
rpsA 1833841 c.300C>G synonymous_variant 0.35 pyrazinamide Uncertain significance
rpsA 1833847 c.306C>G synonymous_variant 0.35 pyrazinamide Uncertain significance
rpsA 1833856 c.315A>G synonymous_variant 0.35 pyrazinamide Uncertain significance
rpsA 1833862 c.321G>T synonymous_variant 0.31 pyrazinamide Uncertain significance
rpsA 1833874 c.333T>G synonymous_variant 0.34 pyrazinamide Uncertain significance
rpsA 1833886 c.345C>G synonymous_variant 0.33 pyrazinamide Uncertain significance
rpsA 1833894 p.Ala118Glu missense_variant 0.34 pyrazinamide Uncertain significance
rpsA 1833928 c.387G>C synonymous_variant 0.37 pyrazinamide Uncertain significance
rpsA 1833949 c.408T>C synonymous_variant 0.32 pyrazinamide Uncertain significance
rpsA 1833961 c.420C>G synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1833970 c.429G>T synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1833979 c.438T>C synonymous_variant 0.28 pyrazinamide Uncertain significance
rpsA 1833991 c.450C>G synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834000 c.459G>C synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834009 c.468C>T synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834012 c.471G>C synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834015 c.474G>C synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834021 c.480C>T synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1834030 c.489C>G synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834033 c.492C>T synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834228 c.687C>A synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834231 c.690T>G synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834234 c.693G>T synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
rpsA 1834240 c.699T>C synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834246 c.705G>T synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834249 c.708T>C synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834252 c.711C>G synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1834261 c.720A>G synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1834279 c.738C>T synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
rpsA 1834294 c.753G>T synonymous_variant 0.33 pyrazinamide Uncertain significance
rpsA 1834297 c.756C>T synonymous_variant 0.35 pyrazinamide Uncertain significance
rpsA 1834303 c.762T>G synonymous_variant 0.33 pyrazinamide Uncertain significance
rpsA 1834306 c.765T>C synonymous_variant 0.34 pyrazinamide Uncertain significance
rpsA 1834327 c.786G>T synonymous_variant 0.31 pyrazinamide Uncertain significance
rpsA 1834357 c.816T>C synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1834366 c.825A>G synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>C synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834396 c.855G>C synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834411 c.870T>G synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834414 c.873C>T synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834417 c.876G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1834420 c.879C>T synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1834423 c.882G>C synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834429 c.888C>T synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834438 c.897C>T synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
rpsA 1834451 c.910T>C synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1834456 c.915T>G synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834468 c.927A>G synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834477 c.936C>T synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
rpsA 1834489 c.948T>C synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834519 c.978G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834520 p.Ala327Ser missense_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834528 c.987T>C synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1834534 c.993C>T synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834609 c.1068T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834645 c.1104C>T synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834666 c.1125G>C synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834667 p.Ala376Ser missense_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834690 c.1149T>C synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834700 p.Gln387Ala missense_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834705 c.1164C>G synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834720 c.1179C>G synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834732 c.1191T>C synonymous_variant 0.24 pyrazinamide Uncertain significance
rpsA 1834738 c.1197A>G synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834753 c.1212T>C synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834759 c.1218A>C synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1834765 p.Glu408Asp missense_variant 0.16 pyrazinamide Uncertain significance
rpsA 1834774 c.1233C>T synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834776 p.Ala412Glu missense_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834780 c.1239A>G synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834789 c.1248T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
bacA 2063685 c.1044G>A synonymous_variant 1.0 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
bacA 2063911 p.Ile273Thr missense_variant 1.0 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Uncertain significance
streptomycin Uncertain significance
PPE35 2169879 p.Phe245Cys missense_variant 1.0 pyrazinamide Uncertain significance
PPE35 2170933 c.-321G>A upstream_gene_variant 1.0 pyrazinamide Uncertain significance
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
kasA 2517917 c.-198G>C upstream_gene_variant 0.29 isoniazid Uncertain significance
kasA 2517941 c.-174C>G upstream_gene_variant 0.31 isoniazid Uncertain significance
kasA 2517953 c.-162C>T upstream_gene_variant 0.26 isoniazid Uncertain significance
kasA 2517962 c.-153C>G upstream_gene_variant 0.24 isoniazid Uncertain significance
kasA 2517968 c.-147T>A upstream_gene_variant 0.2 isoniazid Uncertain significance
kasA 2518756 c.642G>C synonymous_variant 0.18 isoniazid Uncertain significance
kasA 2518825 c.711T>C synonymous_variant 0.14 isoniazid Uncertain significance
ald 3086742 c.-78A>C upstream_gene_variant 1.0 cycloserine Uncertain significance
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine Uncertain significance
lpqB 3623222 c.1689A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
mtrB 3625656 c.958T>C synonymous_variant 0.23 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625705 c.909C>G synonymous_variant 0.27 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625708 c.906C>T synonymous_variant 0.25 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625711 c.903C>T synonymous_variant 0.25 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625720 c.894G>C synonymous_variant 0.3 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.27 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625732 c.882C>T synonymous_variant 0.28 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625735 c.879C>A synonymous_variant 0.26 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625744 c.870G>A synonymous_variant 0.27 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625750 c.864G>A synonymous_variant 0.27 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.31 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625761 p.Gln285Glu missense_variant 0.28 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625762 c.852A>T synonymous_variant 0.29 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625765 c.849C>G synonymous_variant 0.32 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625774 c.840G>A synonymous_variant 0.31 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
lpqB 3625783 c.-873C>T upstream_gene_variant 0.3 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625806 c.808A>C synonymous_variant 0.28 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625807 c.807C>G synonymous_variant 0.29 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625813 c.801C>T synonymous_variant 0.29 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625819 p.Glu265Val missense_variant 0.32 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625837 c.777C>G synonymous_variant 0.3 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625855 c.759G>A synonymous_variant 0.28 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625867 c.747A>G synonymous_variant 0.17 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3626681 c.-68C>T upstream_gene_variant 0.17 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626684 c.-71G>A upstream_gene_variant 0.21 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626704 c.-91C>T upstream_gene_variant 0.24 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626711 c.-98T>C upstream_gene_variant 0.27 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626717 c.-104C>T upstream_gene_variant 0.26 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626726 c.-113T>C upstream_gene_variant 0.28 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626732 c.-119A>G upstream_gene_variant 0.27 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrA 3626741 c.609C>G synonymous_variant 0.25 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrA 3626756 c.594C>G synonymous_variant 0.26 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrA 3626759 c.591T>C synonymous_variant 0.25 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrA 3626762 c.588G>C synonymous_variant 0.27 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrA 3626786 c.564A>G synonymous_variant 0.25 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 0.2 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrA 3626804 c.546A>G synonymous_variant 0.19 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrA 3626825 c.525T>A synonymous_variant 0.15 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>T upstream_gene_variant 0.16 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3627128 c.-515T>C upstream_gene_variant 0.13 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrA 3627133 p.Ala73Ser missense_variant 0.13 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3627139 c.-526T>C upstream_gene_variant 0.15 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3627143 c.-530G>C upstream_gene_variant 0.13 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3627149 c.-536G>A upstream_gene_variant 0.14 bedaquiline Uncertain significance
rifampicin Uncertain significance
rpoA 3877554 c.954G>A synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3877560 c.948C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877569 p.Pro313Thr missense_variant 0.2 rifampicin Uncertain significance
rpoA 3877587 c.921A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3877593 c.915C>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3877614 c.894G>A synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3877620 c.888G>A synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3877665 c.843C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3877677 c.831G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3877836 c.672A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>A synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoA 3877872 c.636C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3877905 c.603A>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3877929 p.Ile193Val missense_variant 0.29 rifampicin Uncertain significance
rpoA 3877962 c.546G>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 0.22 rifampicin Uncertain significance
rpoA 3877974 c.534G>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoA 3877977 p.Lys177Asn missense_variant 0.22 rifampicin Uncertain significance
rpoA 3878160 c.348C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoA 3878259 c.249G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3878271 c.237T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.21 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3878310 c.198G>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3878313 c.195G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
clpC1 4038767 c.1938G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038770 c.1935C>T synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038773 c.1932T>C synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4038782 c.1923G>T synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4038790 c.1915C>T synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
clpC1 4038795 p.Ser637Thr missense_variant 0.21 pyrazinamide Uncertain significance
clpC1 4038812 c.1893T>C synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4038815 c.1890G>T synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4038838 c.1867C>T synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4038860 c.1845G>C synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4038911 c.1794G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038914 c.1791G>T synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038923 c.1782A>T synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038928 c.1777C>A synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038929 c.1776G>A synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4038932 c.1773G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038941 c.1764G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4038956 c.1749T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4038965 c.1740T>C synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4038989 c.1716T>C synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4038997 c.1708T>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039046 c.1659C>G synonymous_variant 0.29 pyrazinamide Uncertain significance
clpC1 4039070 c.1635G>C synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4039077 p.Lys543Arg missense_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039079 c.1626C>G synonymous_variant 0.22 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 0.3 pyrazinamide Uncertain significance
clpC1 4039091 c.1614G>T synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039097 c.1608G>T synonymous_variant 0.3 pyrazinamide Uncertain significance
clpC1 4039103 c.1602T>C synonymous_variant 0.32 pyrazinamide Uncertain significance
clpC1 4039106 c.1599G>C synonymous_variant 0.3 pyrazinamide Uncertain significance
clpC1 4039121 c.1584T>C synonymous_variant 0.36 pyrazinamide Uncertain significance
clpC1 4039142 c.1563A>G synonymous_variant 0.31 pyrazinamide Uncertain significance
clpC1 4039145 c.1560G>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039169 p.Glu512Asp missense_variant 0.29 pyrazinamide Uncertain significance
clpC1 4039172 c.1533A>G synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4039178 c.1527G>C synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039183 c.1522T>C synonymous_variant 0.3 pyrazinamide Uncertain significance
clpC1 4039190 c.1515C>T synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039196 c.1509G>A synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039199 p.Ala502Glu missense_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039208 c.1497C>G synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039220 c.1485G>C synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039262 c.1443C>T synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4039382 c.1323C>G synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039391 c.1314T>C synonymous_variant 0.31 pyrazinamide Uncertain significance
clpC1 4039409 c.1296T>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039412 c.1293T>G synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039415 p.Glu430Asp missense_variant 0.31 pyrazinamide Uncertain significance
clpC1 4039418 c.1287C>G synonymous_variant 0.3 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.33 pyrazinamide Uncertain significance
clpC1 4039442 c.1263A>G synonymous_variant 0.41 pyrazinamide Uncertain significance
clpC1 4039454 c.1251A>G synonymous_variant 0.36 pyrazinamide Not assoc w R - Interim
clpC1 4039466 c.1239T>C synonymous_variant 0.35 pyrazinamide Uncertain significance
clpC1 4039469 c.1236T>C synonymous_variant 0.41 pyrazinamide Uncertain significance
clpC1 4039472 c.1233G>C synonymous_variant 0.38 pyrazinamide Uncertain significance
clpC1 4039478 c.1227G>C synonymous_variant 0.35 pyrazinamide Uncertain significance
clpC1 4039481 c.1224T>C synonymous_variant 0.38 pyrazinamide Uncertain significance
clpC1 4039487 c.1218G>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039522 c.1183C>T synonymous_variant 0.31 pyrazinamide Uncertain significance
clpC1 4039528 c.1177C>A synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4039541 c.1164C>G synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039544 c.1161C>T synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4039559 c.1146C>G synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039565 c.1140G>T synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039570 p.Met379Leu missense_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039571 c.1134G>A synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039574 p.Ala377Gly missense_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039586 c.1119G>C synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039601 c.1104G>A synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039610 c.1095G>C synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039616 c.1089G>C synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039619 c.1086G>A synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039622 c.1083C>T synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039649 c.1056G>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039661 c.1044T>C synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039682 c.1023C>G synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039694 c.1011G>C synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039724 c.981A>G synonymous_variant 0.31 pyrazinamide Uncertain significance
clpC1 4039733 c.972G>A synonymous_variant 0.31 pyrazinamide Uncertain significance
clpC1 4039739 c.966C>G synonymous_variant 0.31 pyrazinamide Uncertain significance
clpC1 4039742 c.963C>T synonymous_variant 0.31 pyrazinamide Uncertain significance
clpC1 4039748 c.957G>C synonymous_variant 0.3 pyrazinamide Uncertain significance
clpC1 4039751 c.954A>G synonymous_variant 0.29 pyrazinamide Uncertain significance
clpC1 4039757 c.948A>G synonymous_variant 0.3 pyrazinamide Uncertain significance
clpC1 4039760 c.945T>C synonymous_variant 0.3 pyrazinamide Uncertain significance
clpC1 4039763 c.942C>T synonymous_variant 0.32 pyrazinamide Not assoc w R - Interim
clpC1 4039769 c.936C>G synonymous_variant 0.33 pyrazinamide Uncertain significance
clpC1 4039778 c.927A>G synonymous_variant 0.33 pyrazinamide Uncertain significance
clpC1 4039793 c.912C>G synonymous_variant 0.32 pyrazinamide Uncertain significance
clpC1 4039814 c.891C>G synonymous_variant 0.34 pyrazinamide Uncertain significance
clpC1 4039817 c.888A>C synonymous_variant 0.29 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.29 pyrazinamide Uncertain significance
clpC1 4039826 c.879C>G synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039831 c.874T>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039832 c.873C>G synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4039850 c.855T>C synonymous_variant 0.26 pyrazinamide Uncertain significance
clpC1 4039868 c.837C>T synonymous_variant 0.23 pyrazinamide Not assoc w R - Interim
clpC1 4039913 c.792C>T synonymous_variant 0.3 pyrazinamide Uncertain significance
clpC1 4039931 c.774T>C synonymous_variant 0.3 pyrazinamide Uncertain significance
clpC1 4039934 c.771G>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039943 c.762G>C synonymous_variant 0.26 pyrazinamide Uncertain significance
clpC1 4039946 c.759A>G synonymous_variant 0.26 pyrazinamide Uncertain significance
clpC1 4039952 c.753T>C synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4039957 c.748C>T synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4039958 c.747G>C synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4039964 c.741C>G synonymous_variant 0.31 pyrazinamide Uncertain significance
clpC1 4039975 p.Asp244Asn missense_variant 0.34 pyrazinamide Uncertain significance
clpC1 4039979 c.726C>G synonymous_variant 0.35 pyrazinamide Uncertain significance
clpC1 4039982 c.723G>A synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
clpC1 4040009 c.696C>G synonymous_variant 0.37 pyrazinamide Uncertain significance
clpC1 4040015 c.690G>C synonymous_variant 0.33 pyrazinamide Uncertain significance
clpC1 4040021 c.684A>T synonymous_variant 0.29 pyrazinamide Uncertain significance
clpC1 4040024 c.681A>G synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4040033 c.672G>C synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4040048 c.657C>T synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4040087 c.618G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040093 c.612C>G synonymous_variant 0.14 pyrazinamide Not assoc w R - Interim
clpC1 4040309 c.396C>T synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4040333 c.372G>C synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4040342 c.363C>A synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4040348 c.357G>T synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4040354 c.351A>G synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4040357 c.348T>C synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4040363 c.342A>C synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4040366 c.339C>T synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4040369 c.336C>G synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4040375 c.330G>C synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4040380 c.325T>C synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4040381 c.324T>C synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4040387 c.318A>G synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4040393 c.312G>C synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040431 c.274T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040441 c.264C>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4040522 c.183T>C synonymous_variant 0.13 pyrazinamide Not assoc w R - Interim
panD 4044138 c.144T>C synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
panD 4044150 c.132A>C synonymous_variant 0.18 pyrazinamide Uncertain significance
panD 4044156 c.126A>G synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
panD 4044167 c.115C>T synonymous_variant 0.18 pyrazinamide Uncertain significance
panD 4044171 c.111C>T synonymous_variant 0.17 pyrazinamide Uncertain significance
panD 4044174 c.108C>T synonymous_variant 0.18 pyrazinamide Uncertain significance
panD 4044180 p.Asp34Glu missense_variant 0.19 pyrazinamide Uncertain significance
panD 4044186 c.94_96delTTGinsCTC synonymous_variant 0.18 pyrazinamide Uncertain significance
panD 4044189 c.93C>T synonymous_variant 0.18 pyrazinamide Uncertain significance
panD 4044194 p.Ala30Pro missense_variant 0.2 pyrazinamide Uncertain significance
panD 4044195 c.87T>C synonymous_variant 0.2 pyrazinamide Uncertain significance
glpK 4138664 c.1092G>C synonymous_variant 0.13 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
embC 4240819 c.957A>C synonymous_variant 0.16 ethambutol Uncertain significance
embC 4240826 p.Ala322Ser missense_variant 0.21 ethambutol Uncertain significance
embC 4240831 c.969T>G synonymous_variant 0.2 ethambutol Uncertain significance
embC 4240859 p.Leu333Met missense_variant 0.15 ethambutol Uncertain significance
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4249594 c.3081G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
ethA 4328376 c.-903G>C upstream_gene_variant 1.0 ethionamide Uncertain significance
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance