Run ID: SRR29017081
Sample name:
Date: 2025-02-11T19:39:32.237870
Number of reads: 170061
Percentage reads mapped: 59.64
Median coverage: 1.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: Sensitive
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4 | Euro-American | None | 0.89 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.94 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | ||||
| pyrazinamide | ||||
| streptomycin | ||||
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | ||||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| gyrB | 6203 | p.Ser322Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6208 | c.969G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6250 | c.1011A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6271 | c.1032C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6280 | c.1041T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6286 | c.1047T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6289 | c.1050C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6292 | c.1053G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6295 | c.1056A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6307 | c.1068T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6310 | c.-992G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6319 | c.1080G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 6331 | c.-971A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6598 | c.-704C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6610 | c.-692C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6613 | c.-689A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6622 | c.-680C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6634 | c.-668T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6637 | c.-665T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6640 | c.-662A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6643 | c.-659A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6649 | c.-653T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6655 | c.-647T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6673 | c.-629A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6676 | c.-626T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6680 | c.1441C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6712 | c.-590G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6730 | c.-572A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6733 | c.-569G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6745 | c.1506T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6763 | c.-539G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6775 | c.1536G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6793 | c.1554T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6797 | p.Gly520Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6841 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8360 | c.1059G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8366 | c.1065G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8375 | c.1074G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 8391 | p.Tyr364His | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8399 | c.1098T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8408 | c.1107A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8420 | c.1119T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8426 | c.1125G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8447 | c.1146C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8450 | c.1149G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8453 | c.1152A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8462 | c.1161A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8852 | c.1551T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8858 | c.1557T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8867 | c.1566A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8873 | c.1572A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8930 | c.1629C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8945 | c.1644G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8946 | c.1645_1647delTTGinsCTC | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8981 | c.1680G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8990 | c.1689C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9029 | c.1728T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9032 | c.1731T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9047 | c.1746C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9051 | c.1750_1752delTTGinsCTA | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9056 | c.1755C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9062 | c.1761C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9065 | c.1764C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9071 | c.1770G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9080 | c.1779G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9089 | c.1788G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9092 | c.1791C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9099 | c.1798_1800delTTAinsCTG | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9104 | c.1803C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9119 | c.1818A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9128 | c.1827C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9335 | c.2034G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9345 | c.2044A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| fgd1 | 491106 | c.324T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491113 | c.331C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491133 | c.351A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491144 | p.Ala121Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491166 | c.384G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491181 | c.399T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491191 | p.Gly137Arg | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491196 | c.414A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491202 | c.420G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491203 | p.Gln141Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491212 | p.Ser144Arg | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491217 | c.435T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491226 | c.444C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491232 | c.450T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491244 | c.462T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491256 | c.474G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491259 | c.477T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491280 | c.498C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491283 | p.Asp167Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491286 | c.504G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fgd1 | 491295 | c.513C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fgd1 | 491296 | p.Val172Ile | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491310 | c.528C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491331 | c.549G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491337 | c.555C>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491343 | c.561C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491349 | c.567T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fgd1 | 491364 | c.582T>C | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491367 | c.585G>C | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491392 | p.Thr204Arg | missense_variant | 0.9 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491526 | c.744T>C | synonymous_variant | 0.92 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491542 | c.760T>C | synonymous_variant | 0.92 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491547 | c.765A>T | synonymous_variant | 0.92 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491550 | c.768T>C | synonymous_variant | 0.92 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491556 | c.774G>A | synonymous_variant | 0.92 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fgd1 | 491562 | c.780C>T | synonymous_variant | 0.92 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491563 | c.781_782delAGinsTC | synonymous_variant | 0.92 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491589 | c.807G>A | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491601 | c.819T>C | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491607 | c.825G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491610 | c.828A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491616 | c.834A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491620 | p.Ile280Val | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491640 | c.858G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491649 | c.867C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491658 | c.876A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| mshA | 574650 | c.-698A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574655 | c.-693C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574664 | c.-684G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574667 | c.-681G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574671 | c.-677_-675delGCAinsACG | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574678 | c.-670G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574688 | c.-660G>C | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| mshA | 574694 | c.-654C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574697 | c.-651C>T | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| mshA | 574718 | c.-630A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574721 | c.-627C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574738 | c.-610_-609delGTinsAC | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| ccsA | 620604 | c.714C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620607 | c.717T>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620613 | c.723C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620631 | c.741T>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620685 | c.795G>A | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| capreomycin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| ccsA | 620688 | c.798G>T | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620692 | p.Ser268Ala | missense_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620697 | c.807C>T | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620698 | p.Val270Ile | missense_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620703 | c.813G>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620718 | c.828G>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620721 | c.831G>A | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620730 | c.840C>T | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620733 | c.843G>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620734 | c.844C>A | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620739 | c.849A>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620748 | c.858T>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620754 | c.864G>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620763 | c.873G>A | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| Rv0565c | 656478 | c.993C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656487 | c.984T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656511 | c.960T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656526 | p.Glu315Asp | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656538 | p.Ser311Glu | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656542 | p.Thr310Gly | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656547 | c.924C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656550 | p.Asn307Val | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656559 | c.912C>T | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656568 | c.903G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656583 | c.888A>G | synonymous_variant | 1.0 | ethionamide | |
| rpoB | 759604 | c.-203A>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 759606 | c.-201T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759616 | c.-191C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759643 | c.-164T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759647 | c.-160T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 759655 | c.-151delA | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759661 | c.-146G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759672 | c.-135G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759674 | c.-133T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759678 | c.-129T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759679 | c.-128T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759693 | c.-114C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759694 | c.-113C>T | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 759701 | c.-106A>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 760253 | c.447T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760298 | c.492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760307 | c.501T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760310 | c.504G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760313 | c.507G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760328 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760343 | c.537G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760370 | c.564C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760389 | c.583_585delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760406 | c.600G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760454 | c.648C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760457 | c.651C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760522 | p.Ser239Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760532 | c.726T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760533 | p.Val243Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 760547 | c.741G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760563 | p.Arg253Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760616 | c.810C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760634 | c.828T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760646 | c.840C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760649 | c.843G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760655 | c.849A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760661 | c.855A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760670 | c.864G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760674 | c.868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760679 | c.873A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760683 | c.877T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760796 | c.990A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760805 | c.999G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760817 | c.1011A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760820 | c.1014T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760826 | c.1020C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760830 | c.1024T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760841 | c.1035T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760844 | p.Gln346His | missense_variant | 0.96 | rifampicin | |
| rpoB | 760845 | p.Thr347Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760859 | c.1053T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760862 | c.1056G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760868 | c.1062C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760916 | c.1110C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760920 | p.Leu372Ile | missense_variant | 1.0 | rifampicin | |
| rpoB | 760934 | c.1128C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763408 | c.39T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763411 | c.42T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763414 | c.45T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763420 | c.51G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763423 | p.Glu18Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 763430 | c.61_63delAGGinsCGT | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763435 | c.66A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763468 | c.99G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763483 | c.114G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763484 | c.115_117delCTTinsTTG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763618 | c.249C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763633 | c.264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763675 | c.306C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763702 | c.333C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763714 | c.345G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763732 | c.363C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763872 | p.Gly168Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 763876 | p.Glu169Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763885 | c.516C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763886 | c.517C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 763891 | c.522G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763900 | c.531G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763936 | c.567C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763939 | c.570G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763978 | c.609C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763996 | c.627T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764002 | c.633C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764005 | c.636G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764011 | c.642T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764024 | c.655_657delTTGinsCTC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764040 | p.Ser224Asn | missense_variant | 1.0 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764059 | c.690G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764086 | c.717C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764089 | c.720C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764098 | c.729A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764101 | c.732C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764131 | c.762T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764134 | c.765C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764185 | c.816C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764195 | p.Ser276Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 764203 | c.834G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764206 | p.Asp279Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 764212 | c.843C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764242 | c.873C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764245 | c.876C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764246 | c.877_879delCTCinsTTG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764254 | c.885G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764255 | c.886C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764266 | c.897T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764269 | c.900G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764284 | c.915G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764317 | c.948C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764320 | c.951C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764329 | c.960C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764380 | c.1011G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764383 | c.1014C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764386 | c.1017C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764392 | c.1023C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764404 | c.1035C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764405 | c.1036A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764431 | c.1062G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764503 | c.1134G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764506 | c.1137C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764510 | c.1141C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764527 | c.1158C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764545 | c.1176C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764548 | c.1179G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764554 | c.1185C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764563 | c.1194G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764578 | c.1209C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764587 | c.1218C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764590 | c.1221G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764593 | c.1224C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764602 | c.1233C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764611 | c.1242G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764626 | c.1257C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764656 | c.1287C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764659 | c.1290C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764692 | c.1323C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764696 | c.1327C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764791 | c.1422C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764800 | c.1431G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764803 | c.1434C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 764812 | c.1443C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764824 | c.1455T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764851 | c.1482C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764878 | c.1509C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764902 | c.1533C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764923 | c.1554A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764932 | c.1563C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765493 | c.2124G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765544 | c.2175C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765547 | c.2178C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765548 | c.2179_2180delAGinsTC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765553 | c.2184C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765571 | c.2202C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765596 | p.Lys743Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 765611 | p.His748Ser | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765625 | c.2256C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765628 | c.2259G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765658 | c.2289C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765727 | c.2358T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765739 | c.2370G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765871 | c.2502T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765874 | c.2505G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765875 | p.Val836Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765883 | c.2514C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765904 | c.2535C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765908 | c.2539C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765937 | c.2568T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765961 | c.2592G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765979 | c.2610C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765985 | c.2616C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766021 | c.2652G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766027 | c.2658G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766034 | p.His889Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 766043 | p.Gln892Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 766345 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766351 | c.2982C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766354 | c.2985C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766357 | c.2988C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766363 | c.2994G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766369 | c.3000C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766375 | c.3006C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766459 | c.3090G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766486 | c.3117A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766489 | c.3120G>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766495 | c.3126C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766528 | c.3159T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766531 | c.3162G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766534 | c.3165C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766540 | p.Asp1057Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766564 | c.3195C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766570 | c.3201T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766585 | c.3216T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766621 | c.3252G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766624 | c.3255G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766645 | c.3276A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766652 | p.Ser1095Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766661 | p.Val1098Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766667 | p.Ser1100Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766690 | c.3321G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766714 | c.3345G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766750 | c.3381C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766798 | c.3429C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766801 | c.3432C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766807 | c.3438T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766843 | c.3474T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766846 | c.3477C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766861 | c.3492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766921 | c.3552G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766933 | c.3564A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766942 | c.3573C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766972 | c.3603G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766975 | c.3606C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766981 | c.3612T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766996 | c.3627C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767002 | c.3633G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767062 | c.3693C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767068 | c.3699G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767152 | c.3783T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767158 | c.3789T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767163 | p.Asn1265Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 767167 | c.3798C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767212 | c.3843G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpsL | 781134 | c.-426T>C | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781138 | c.-422_-420delCAGinsGAA | upstream_gene_variant | 1.0 | streptomycin | |
| rplC | 800498 | c.-311G>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800516 | c.-293G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800531 | c.-278T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800546 | c.-263T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800567 | c.-242A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800570 | c.-239C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800579 | c.-230C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800585 | c.-224T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800594 | c.-215C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800597 | c.-212A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800600 | c.-209G>T | upstream_gene_variant | 0.98 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800618 | c.-191T>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800633 | c.-176T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800639 | c.-170C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800648 | c.-161A>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800654 | c.-155T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800684 | c.-125G>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800693 | c.-116A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800723 | c.-86C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800726 | c.-83G>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800747 | c.-62C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800753 | c.-56C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800762 | c.-47T>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800832 | c.24T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800838 | c.30G>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 800844 | c.36T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800856 | c.48A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800865 | c.57A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800867 | p.Ser20Asn | missense_variant | 1.0 | linezolid | |
| rplC | 800872 | c.64_66delAGAinsCGG | synonymous_variant | 1.0 | linezolid | |
| rplC | 800877 | c.69A>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 800880 | c.72A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800907 | c.99C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800916 | c.108A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800922 | c.114C>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 800925 | c.117C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 800931 | c.123G>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 800937 | c.129A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800940 | c.132C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 800946 | c.138T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800949 | c.141T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800955 | c.147C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800962 | c.154C>T | synonymous_variant | 1.0 | linezolid | |
| fbiC | 1304682 | c.1752C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304694 | c.1764A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304709 | c.1779C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304715 | c.1785G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304721 | c.1791C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304724 | c.1794A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1304727 | c.1797A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304742 | c.1812T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304748 | c.1818T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304751 | c.1821C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304755 | c.1825_1827delCTAinsTTG | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304779 | c.1849C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304784 | c.1854T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304787 | c.1857T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| sigE | 1364889 | c.477A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364895 | p.Glu161Asp | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364919 | c.507T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364952 | c.540A>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364955 | c.543G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364961 | c.549A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364976 | c.564T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364979 | c.567C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364980 | c.568T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364984 | p.Ala191Asp | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1365003 | c.591T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365006 | c.594T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365012 | c.600G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365019 | c.607C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365024 | c.612T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365036 | c.624T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365042 | c.630G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365045 | c.633C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rrs | 1471935 | n.90T>C | non_coding_transcript_exon_variant | 0.57 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1471996 | n.151C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472056 | n.211G>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472057 | n.212C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| inhA | 1673596 | c.-606A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673601 | c.-601G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673607 | c.-595T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673616 | c.-586A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673633 | c.-569G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673640 | c.-562C>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673646 | c.-556T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673657 | c.-545_-544delCGinsAA | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673660 | c.-542C>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673664 | c.-538A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673667 | c.-535A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673670 | c.-532G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673679 | c.-523T>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673712 | c.-490A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673713 | c.-489T>G | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| inhA | 1673724 | c.-478A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673745 | c.-457G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673748 | c.-454A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673756 | c.-446_-445delAGinsTC | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673767 | c.-435A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673799 | c.-403T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673802 | c.-400A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673808 | c.-394A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673825 | c.-376_-373delCAAC | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673832 | c.-370_-369insGCGG | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673838 | c.-364T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673847 | c.-355A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673853 | c.-349A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673865 | c.-337C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673870 | c.-332_-331delGCinsCG | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673895 | c.-307C>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673901 | c.-301A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673916 | c.-286A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673917 | c.-285G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673922 | c.-280T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673925 | c.-277C>T | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| inhA | 1673934 | c.-268C>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673943 | c.-259C>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673952 | c.-250G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673953 | c.-249T>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673961 | c.-241A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674006 | c.-196T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674024 | c.-178T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674033 | c.-169T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674037 | c.-165_-164delCAinsGC | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674045 | c.-157G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674049 | c.-153C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674054 | c.-148T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674060 | c.-142A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674072 | c.-130C>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674079 | c.-123C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674083 | c.-119C>A | upstream_gene_variant | 0.92 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674096 | c.-106G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674108 | c.-94C>T | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| inhA | 1674177 | c.-25C>T | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| inhA | 1674184 | c.-17_-16delAC | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674186 | c.-16C>G | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| inhA | 1674188 | c.-14A>G | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| inhA | 1674199 | c.-3C>G | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| inhA | 1674205 | p.Thr2Ala | missense_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| inhA | 1674216 | c.15G>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674219 | p.Asp6Glu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| rpsA | 1833518 | c.-24C>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833536 | c.-6_-3delAACAinsCCC | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833568 | c.27G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833589 | c.48A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833595 | c.54T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833616 | c.75A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833619 | c.78A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833628 | c.87G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833634 | c.93G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833664 | c.123C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833670 | c.129C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833676 | c.135A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833679 | c.138G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833694 | c.153G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833697 | c.156C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833718 | c.177C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833724 | c.183C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833730 | c.189C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833734 | p.Ala65Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833742 | c.201A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833778 | c.237C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833781 | c.240T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833790 | c.249T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833794 | p.Glu85Lys | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833811 | c.270G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833832 | c.291G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833862 | c.321G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833874 | c.333T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833886 | c.345C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833952 | c.411C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833971 | c.430C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833976 | c.435C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833995 | c.454C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834030 | c.489C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834099 | c.558C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834102 | c.561T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834105 | c.564C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834108 | c.567C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834114 | c.573G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834150 | c.609G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834153 | c.612T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834154 | p.Asn205Gln | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834157 | c.616T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834162 | c.621A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834165 | c.624A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834169 | p.Thr210Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834186 | c.645C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834222 | c.681T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834261 | c.720A>C | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834264 | c.723G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834297 | c.756C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834375 | c.834G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834411 | c.870T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834417 | c.876G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834423 | c.882G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834435 | c.894G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834465 | c.924T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834474 | c.933C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834531 | c.990C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834555 | c.1014T>C | synonymous_variant | 1.0 | pyrazinamide | |
| tsnR | 1853370 | c.-236_-234delGCAinsTCG | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853390 | c.-216G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 1.0 | linezolid | |
| kasA | 2518156 | c.42T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518162 | c.48G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518174 | c.60A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518186 | c.72G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518190 | p.Ser26Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518220 | c.106C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518234 | c.120G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518248 | p.Ala45Val | missense_variant | 1.0 | isoniazid | |
| kasA | 2518255 | c.141A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518268 | p.Thr52Ser | missense_variant | 0.96 | isoniazid | |
| kasA | 2518282 | c.168A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518283 | p.Ala57Pro | missense_variant | 1.0 | isoniazid | |
| kasA | 2518300 | c.186T>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518312 | p.Asp66Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518315 | c.201G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518462 | c.348A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518468 | c.354A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518475 | c.361A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518480 | c.366T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518486 | c.372G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518504 | c.390T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518506 | p.Ala131Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518519 | c.405G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518522 | c.408G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518528 | c.414C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518540 | c.426T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518561 | c.447T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518570 | c.456_457insACC | conservative_inframe_insertion | 1.0 | isoniazid | |
| kasA | 2518573 | c.460_462delATC | conservative_inframe_deletion | 1.0 | isoniazid | |
| kasA | 2518588 | c.474T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518591 | c.477G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518624 | c.510C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518636 | c.522C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518642 | c.528A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518645 | c.531G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518651 | c.537C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518663 | c.549T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518672 | c.558G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518768 | c.654C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518780 | p.Glu222Asp | missense_variant | 1.0 | isoniazid | |
| kasA | 2518783 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518786 | c.672G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518787 | p.Arg225Gly | missense_variant | 1.0 | isoniazid | |
| kasA | 2518792 | c.678C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518795 | c.681C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518798 | c.684G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518822 | c.708C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518864 | c.750G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519092 | c.978C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519095 | c.981C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519097 | p.Val328Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2519101 | c.987C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519104 | c.990T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519110 | p.Asp332Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2519113 | p.Gln333His | missense_variant | 1.0 | isoniazid | |
| kasA | 2519135 | p.Ser341Gly | missense_variant | 1.0 | isoniazid | |
| kasA | 2519158 | c.1044C>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519167 | c.1053T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519171 | c.1057_1059delCTCinsTTG | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726285 | c.93C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726303 | c.111T>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726312 | c.120T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726315 | p.Asp41Glu | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726318 | p.Glu42Asp | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726319 | p.His43Tyr | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726322 | p.Pro44Asp | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726336 | c.144G>A | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726340 | p.Val50Ile | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726348 | c.156T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726357 | c.165A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726378 | c.186T>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726381 | c.189C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726390 | c.198G>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726397 | p.Ser69Gly | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726405 | c.213C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726408 | c.216T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726432 | c.240C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726436 | p.Ile82Val | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726441 | c.249G>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726444 | c.252G>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726447 | c.255T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726451 | p.Ile87Val | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726467 | p.Ala92Val | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726471 | c.279T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726483 | c.291T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726486 | c.294A>C | synonymous_variant | 1.0 | isoniazid | |
| Rv2477c | 2783350 | c.693T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783353 | c.690T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783359 | c.684G>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783362 | c.681G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783374 | c.669G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783386 | c.657G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783395 | c.648T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783422 | c.621T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783425 | p.Pro206Gln | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783432 | p.Ser204Ala | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783440 | c.603T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783461 | c.582T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783467 | c.576G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783473 | c.570A>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783805 | p.Asn80Asp | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783815 | c.228A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783821 | c.222A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783872 | c.171G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783914 | c.129T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783917 | c.126C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783938 | c.105T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783950 | c.93C>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| pepQ | 2859704 | c.715T>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859723 | c.696T>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | Not assoc w R - Interim | |||||
| pepQ | 2859732 | c.687C>T | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859747 | c.672C>G | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859765 | c.654G>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859771 | c.648T>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859778 | p.Val214Ala | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859780 | p.Gln213Ala | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859804 | c.615C>T | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859827 | p.Ala198Ser | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| Rv2752c | 3064914 | c.1278T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| Rv2752c | 3064923 | c.1269C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064932 | c.1260T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064935 | c.1257A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064941 | p.Gln417Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064947 | c.1245A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064950 | c.1242C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064956 | p.Ser412Arg | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| ethambutol | Uncertain significance | |||||
| Rv2752c | 3064998 | c.1194A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065013 | c.1179G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065031 | c.1161G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| thyX | 3067304 | p.Glu214Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067316 | c.630A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067334 | c.612C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067340 | c.606G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067355 | c.591A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067391 | c.555G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067394 | c.552G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067433 | c.513C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067439 | c.507A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067442 | c.504C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067457 | c.489C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067463 | p.Ile161Val | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067472 | c.474C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067475 | c.471A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067515 | p.Ser144Thr | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067583 | c.363C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067586 | c.360C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067595 | c.351C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067602 | p.Arg115Gln | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067607 | p.Asp113Asn | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067616 | c.330C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067619 | c.327A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067631 | c.315C>G | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyX | 3067634 | c.312C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067640 | c.306G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067652 | c.294T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067661 | c.285C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067670 | c.276G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067679 | c.267C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067685 | c.261A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067688 | c.258G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067727 | c.219A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067742 | c.204A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067761 | p.Arg62Lys | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067765 | p.Leu61Ile | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067766 | c.180C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067769 | p.Gly59Ala | missense_variant | 0.96 | para-aminosalicylic_acid | |
| thyX | 3067781 | c.165C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067790 | c.156C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067793 | c.153T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067814 | c.132T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067840 | p.Val36Leu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067847 | p.Pro33Gln | missense_variant | 0.96 | para-aminosalicylic_acid | |
| thyX | 3067850 | c.96A>T | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyX | 3067869 | p.Thr26Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067874 | c.72C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067880 | p.Asp22Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067886 | c.60A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067889 | c.57C>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067898 | p.Asp16Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074061 | p.Glu137Asp | missense_variant | 0.91 | para-aminosalicylic_acid | |
| thyA | 3074097 | c.375C>G | synonymous_variant | 0.92 | para-aminosalicylic_acid | |
| thyA | 3074100 | c.372T>C | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
| thyA | 3074103 | c.369C>G | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
| thyA | 3074106 | c.366T>C | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
| thyA | 3074154 | c.318T>C | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
| lpqB | 3624518 | c.393T>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624521 | c.390G>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624527 | p.Gln128Val | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624530 | c.381T>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624545 | c.366T>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624563 | c.348C>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624569 | c.342C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3624581 | c.330A>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625675 | c.-765G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625681 | c.933G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625695 | c.-785C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625711 | c.903C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625720 | c.894G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625750 | c.864G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625753 | c.-843C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625762 | c.852A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625765 | c.849C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625771 | c.843C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625837 | c.777C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625846 | c.-936G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625852 | c.-942A>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625855 | c.759G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625864 | c.-954T>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625867 | c.747A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625874 | p.Ile247Thr | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625876 | c.-966G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625881 | p.Ser245Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| bedaquiline | ||||||
| lpqB | 3625882 | c.-972G>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625885 | p.Ser243Ala | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625888 | c.-978G>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625912 | c.702G>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625915 | c.699G>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625930 | c.684C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mtrB | 3625936 | c.678C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625942 | c.672C>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625945 | c.669A>T | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626705 | c.-92G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626708 | c.-95G>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626711 | c.-98T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626723 | c.-110C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626773 | c.-160C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626774 | c.-163_-161delAGGinsCGC | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626792 | c.558G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626798 | c.-185T>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626804 | c.546A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626843 | c.-230G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626846 | c.504G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626852 | c.-239G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626857 | c.-244T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626912 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626924 | c.-311G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626930 | c.-317A>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626939 | p.Glu137Asp | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626969 | c.-356C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626996 | c.-383G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627026 | c.324G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mtrA | 3627056 | c.294C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3627068 | c.282T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3627080 | c.270T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 0.96 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627086 | c.-473C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627098 | c.252A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627110 | c.-497G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627119 | c.231T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627128 | c.-515T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627134 | c.-521C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627139 | c.-526T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627167 | c.-554T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627187 | c.163T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627188 | c.-577_-575delTTAinsCTG | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627197 | c.-584T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627218 | c.-605G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| fbiB | 3642635 | c.1101C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642656 | c.1122G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642662 | c.1128C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642665 | c.1131C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642668 | c.1134A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642674 | c.1140C>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642677 | c.1143A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642680 | c.1146A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642683 | c.1149C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642684 | c.1150T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642687 | c.1153C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642698 | c.1164G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiB | 3642701 | c.1167C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642704 | c.1170G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642710 | c.1176G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642711 | p.Leu393Val | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642719 | c.1185T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642731 | c.1197C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| rpoA | 3877587 | c.921A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877593 | c.915C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877598 | c.910C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877613 | p.Ile299Val | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877617 | c.891G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877629 | c.879C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877638 | c.870T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877656 | c.852T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877668 | c.840A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877679 | p.Ala277Ser | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877692 | c.816G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877707 | c.801G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877731 | c.777G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877737 | c.771G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877770 | c.738A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877773 | c.735G>A | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877818 | c.690A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877839 | c.669G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877848 | c.660C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877875 | c.633T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877881 | c.627G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877920 | c.588G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877926 | c.582G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877962 | c.546G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877971 | c.537C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877986 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878022 | c.486T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878025 | c.483C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878028 | c.480G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878031 | c.477T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878046 | c.462T>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878050 | p.Arg153Lys | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878055 | c.453A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878061 | c.447G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878082 | c.426T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878103 | c.405A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878130 | c.378C>G | synonymous_variant | 0.92 | rifampicin | |
| rpoA | 3878143 | p.Gly122Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878163 | c.345C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878196 | c.312G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878205 | c.303T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878226 | c.282C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878229 | c.279C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878247 | c.261G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878253 | c.255G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878276 | c.232C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878283 | p.Glu75Asp | missense_variant | 0.98 | rifampicin | Uncertain significance |
| rpoA | 3878292 | c.216T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878298 | c.210A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878304 | c.204G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878313 | c.195G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878331 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878337 | c.171T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878346 | c.162T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878358 | c.150C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878364 | c.144A>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878385 | c.123C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878391 | c.117T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878400 | c.108T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878406 | c.102G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878409 | c.99C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878436 | c.72A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878442 | c.66G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878728 | c.-221G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878736 | c.-229A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878749 | c.-242G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878755 | c.-248G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878758 | c.-251G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878785 | c.-278T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878791 | c.-284C>T | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878794 | c.-287G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878797 | c.-290G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878803 | c.-296G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878823 | c.-316G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878843 | c.-337_-336delCGinsAA | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878848 | c.-341C>T | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878875 | c.-368C>T | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878886 | c.-379G>A | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878890 | c.-383C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878893 | c.-388_-386delCACinsAAG | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878896 | c.-389G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878908 | c.-403_-401delAACinsCTG | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878917 | c.-410G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878935 | c.-428C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878956 | c.-449G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878974 | c.-469_-467delATCinsGTG | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878977 | c.-470C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3879006 | c.-499A>C | upstream_gene_variant | 1.0 | rifampicin | |
| ddn | 3986636 | c.-208C>G | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| ddn | 3986646 | c.-198_-196delCTCinsTTG | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clpC1 | 4038320 | c.2385G>C | synonymous_variant | 0.9 | pyrazinamide | |
| clpC1 | 4038323 | c.2382C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038347 | c.2358G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038353 | p.Gln784Ala | missense_variant | 0.96 | pyrazinamide | |
| clpC1 | 4038356 | c.2349T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038368 | c.2337T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038388 | c.2317T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038392 | c.2313C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038395 | c.2310C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038398 | c.2307G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038403 | c.2302T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038419 | c.2286T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038436 | p.Ala757Ser | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038444 | p.Ala754Lys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038446 | c.2259T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038485 | c.2220delCinsAAAAG | frameshift_variant&synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038497 | p.Ser736Gly | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038500 | c.2205C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038509 | p.Asp732Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038530 | p.Glu725Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038536 | c.2169C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038569 | c.2136C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038587 | c.2118C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038602 | c.2103G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038640 | p.Asp689Asn | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038653 | c.2052C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038658 | p.Lys683Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038660 | c.2044_2045delTCinsAG | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038662 | c.2043T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038674 | c.2031C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038679 | p.Pro676Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038680 | c.2025G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038683 | c.2022T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038694 | p.Ser671Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038701 | c.2004G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038764 | c.1941C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038767 | c.1938G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038770 | c.1935C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038842 | c.1863G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038845 | c.1860G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.99 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038923 | c.1782A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039001 | p.Asn568Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039064 | c.1641C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039085 | c.1620A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039103 | c.1602T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039112 | c.1593C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039124 | c.1581C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039133 | c.1572C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039169 | c.1536A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039178 | c.1527G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039190 | c.1515C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039243 | c.1462C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039286 | c.1419T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039292 | c.1413C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039295 | c.1410A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039298 | c.1407T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039319 | c.1386T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039322 | c.1383T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039328 | c.1377A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039331 | c.1374C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039334 | c.1371G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039337 | p.Thr456Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039343 | c.1362G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039346 | c.1359G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039352 | c.1353C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039364 | c.1341C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039382 | c.1323C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039391 | c.1314T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039394 | c.1311G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039397 | c.1308A>G | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4039406 | c.1299G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039409 | c.1296T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039412 | c.1293T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039586 | c.1119G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039610 | c.1095G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039616 | c.1089G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039622 | c.1083C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040135 | c.570C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040144 | c.561G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040147 | c.558A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040153 | c.552A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040168 | c.537G>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040171 | c.534C>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4040201 | c.504C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040207 | c.498T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040213 | c.492T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040225 | c.480A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040228 | c.477G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040240 | c.465C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040246 | c.459C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040255 | p.Ala150Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040267 | c.438A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040279 | c.426C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040300 | c.405C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040303 | c.402G>T | synonymous_variant | 1.0 | pyrazinamide | |
| embC | 4241047 | c.1185C>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241050 | c.1188T>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241071 | c.1209C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241095 | c.1233C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241129 | c.1267C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241140 | c.1278A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241141 | p.Ile427Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4241146 | c.1284C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241158 | c.1296T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241161 | c.1299C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241162 | c.1300T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241194 | c.1332C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241203 | c.1341T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241215 | c.1353C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241218 | c.1356G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241518 | c.1656A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241521 | c.1659T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241528 | c.1666_1668delCGCinsAGG | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241536 | c.1674A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241539 | c.1677T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241545 | c.1683T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241548 | c.1686T>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241551 | c.1689A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241554 | c.1692G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241560 | c.1698C>T | synonymous_variant | 0.91 | ethambutol | |
| embC | 4241656 | c.1794G>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241665 | c.1803G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241671 | c.1809T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241674 | c.1812C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241677 | c.1815G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241691 | p.Gly610Ala | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4241695 | c.1833T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241713 | c.1851G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241719 | c.1857G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241723 | p.Val621Met | missense_variant | 1.0 | ethambutol | |
| embC | 4241734 | c.1872C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241735 | p.Val625Leu | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4241741 | p.Val627Leu | missense_variant | 1.0 | ethambutol | |
| embC | 4241750 | p.Leu630Val | missense_variant | 1.0 | ethambutol | |
| embC | 4241755 | c.1893C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244219 | c.987C>G | synonymous_variant | 0.9 | ethambutol | |
| embA | 4244233 | p.Ala334Val | missense_variant | 0.91 | ethambutol | Uncertain significance |
| embA | 4244247 | p.Val339Ile | missense_variant | 0.92 | ethambutol | |
| embA | 4244255 | c.1023T>C | synonymous_variant | 0.92 | ethambutol | Not assoc w R - Interim |
| embA | 4244257 | p.Phe342Tyr | missense_variant | 0.92 | ethambutol | |
| embA | 4244260 | p.Val343Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4244267 | c.1035G>A | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244276 | c.1044A>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244279 | c.1047G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244283 | p.Pro351Lys | missense_variant | 1.0 | ethambutol | |
| embA | 4244291 | c.1059G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244309 | c.1077C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244312 | c.1080T>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4244315 | c.1083G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244317 | p.Phe362Trp | missense_variant | 1.0 | ethambutol | |
| embA | 4244324 | c.1092T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4244327 | c.1095T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244340 | p.Ser370Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4244345 | c.1113C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245136 | p.Tyr635Phe | missense_variant | 1.0 | ethambutol | |
| embA | 4245149 | c.1917C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245158 | c.1926C>A | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245183 | c.1951C>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245186 | p.Thr652Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4245189 | p.Leu653Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4245197 | c.1965C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4245198 | p.Leu656Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4245215 | c.1983A>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245222 | p.Tyr664Gln | missense_variant | 1.0 | ethambutol | |
| embB | 4245737 | c.-777A>T | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245740 | c.-774T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245764 | c.-750G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245772 | p.Asn847Ser | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4245776 | c.2544G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4245785 | c.2553G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4245794 | c.-720G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245797 | c.-717C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245806 | c.-708G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245807 | c.-707_-705delTTAinsCTG | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245815 | c.-699C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245820 | p.Ser863Thr | missense_variant | 1.0 | ethambutol | |
| embB | 4245836 | c.-678G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245842 | c.-672G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245845 | c.-669T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245848 | c.-666C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245851 | c.-663G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245875 | c.-639G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4248118 | c.1605T>C | synonymous_variant | 0.92 | ethambutol | |
| embB | 4248133 | c.1620C>G | synonymous_variant | 0.92 | ethambutol | |
| embB | 4248167 | p.Thr552Ala | missense_variant | 0.91 | ethambutol | |
| embB | 4248173 | p.Val554Leu | missense_variant | 0.92 | ethambutol | |
| embB | 4248190 | c.1677G>C | synonymous_variant | 0.94 | ethambutol | Not assoc w R - Interim |
| embB | 4248199 | c.1686A>G | synonymous_variant | 0.93 | ethambutol | |
| embB | 4248200 | p.Ile563Val | missense_variant | 0.94 | ethambutol | |
| embB | 4248206 | p.Ser565Gly | missense_variant | 0.94 | ethambutol | Uncertain significance |
| embB | 4248220 | c.1707A>G | synonymous_variant | 0.94 | ethambutol | Not assoc w R - Interim |
| embB | 4248226 | c.1713G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248313 | c.1800C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248319 | c.1806A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248322 | c.1809G>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248373 | c.1860C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248385 | c.1872C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248398 | p.Leu629Val | missense_variant | 0.96 | ethambutol | |
| embB | 4248403 | c.1890G>T | synonymous_variant | 0.96 | ethambutol | |
| embB | 4248407 | p.Leu632Val | missense_variant | 0.96 | ethambutol | |
| embB | 4248412 | c.1899C>T | synonymous_variant | 0.96 | ethambutol | Not assoc w R - Interim |
| embB | 4248416 | p.Leu635Met | missense_variant | 0.96 | ethambutol | |
| embB | 4248430 | c.1917T>C | synonymous_variant | 0.96 | ethambutol | |
| embB | 4248432 | p.Trp640Phe | missense_variant | 0.96 | ethambutol | |
| embB | 4248457 | c.1944T>C | synonymous_variant | 0.95 | ethambutol | |
| embB | 4248460 | c.1947C>G | synonymous_variant | 0.95 | ethambutol | |
| embB | 4248463 | c.1950C>G | synonymous_variant | 0.95 | ethambutol | |
| embB | 4248472 | c.1959T>C | synonymous_variant | 0.95 | ethambutol | |
| embB | 4248490 | c.1977G>A | synonymous_variant | 0.95 | ethambutol | Not assoc w R - Interim |
| embB | 4248508 | c.1995G>A | synonymous_variant | 0.95 | ethambutol | Not assoc w R - Interim |
| embB | 4248514 | c.2001A>G | synonymous_variant | 0.94 | ethambutol | |
| ubiA | 4269110 | p.Gly242Arg | missense_variant | 0.9 | ethambutol | |
| aftB | 4269117 | c.-281G>A | upstream_gene_variant | 0.92 | ethambutol | |
| aftB | 4269129 | c.-293G>T | upstream_gene_variant | 0.94 | ethambutol | |
| aftB | 4269138 | c.-302C>T | upstream_gene_variant | 0.95 | ethambutol | |
| ubiA | 4269143 | p.Leu231Val | missense_variant | 0.95 | ethambutol | |
| ubiA | 4269144 | c.690C>G | synonymous_variant | 0.95 | ethambutol | Not assoc w R - Interim |
| aftB | 4269150 | c.-314G>C | upstream_gene_variant | 0.95 | ethambutol | |
| ubiA | 4269164 | p.Leu224Met | missense_variant | 0.95 | ethambutol | |
| aftB | 4269165 | c.-329G>C | upstream_gene_variant | 0.95 | ethambutol | |
| aftB | 4269201 | c.-365A>G | upstream_gene_variant | 0.95 | ethambutol | |
| aftB | 4269210 | c.-374G>A | upstream_gene_variant | 0.95 | ethambutol | |
| ubiA | 4269220 | p.Ala205Lys | missense_variant | 0.94 | ethambutol | |
| ubiA | 4269222 | c.612T>C | synonymous_variant | 0.94 | ethambutol | Not assoc w R - Interim |
| aftB | 4269234 | c.-398A>G | upstream_gene_variant | 0.94 | ethambutol | |
| ubiA | 4269242 | p.Leu198Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
| ubiA | 4269243 | p.His197Gln | missense_variant | 1.0 | ethambutol | |
| aftB | 4269249 | c.-413G>A | upstream_gene_variant | 1.0 | ethambutol | |
| aftB | 4269264 | c.-428C>A | upstream_gene_variant | 1.0 | ethambutol |
