TB-Profiler result

Run: ERR4188322
Summary

Run ID: ERR4188322

Sample name:

Date: 2024-10-04T21:46:44.255018

Number of reads: 333560

Percentage reads mapped: 31.1

Median coverage: 9.0

Strain: lineage4.6.4;lineage4.9

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.6.4 Euro-American None 0.07
lineage4 Euro-American None 0.75
lineage4.9 Euro-American (H37Rv-like) None 0.88
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.His312Arg Mutation from literature
p.Tyr384Asn Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin tlyA c.1dupG Assoc w R
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
tlyA 1917939 c.1dupG frameshift_variant 1.0 capreomycin Assoc w R
embB 4247448 p.His312Arg missense_variant 1.0 ethambutol Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 1.0 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 802 c.802C>T synonymous_variant 1.0 isoniazid
dnaA 805 c.805_807delTTGinsCTC synonymous_variant 1.0 isoniazid
dnaA 810 c.810C>G synonymous_variant 1.0 isoniazid
dnaA 813 c.813C>T synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 1.0 isoniazid
dnaA 927 c.927G>A synonymous_variant 1.0 isoniazid
dnaA 1179 c.1179G>C synonymous_variant 1.0 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 1.0 isoniazid
gyrB 5377 c.138T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6086 p.Thr283Pro missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6097 c.858G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6121 c.882C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6299 c.1060C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6313 c.-989C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7595 c.294C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7619 c.318C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7622 c.321C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7766 c.465C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7769 c.468C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7838 c.537C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7850 c.549C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8084 c.783G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8090 c.789C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8105 c.804G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8189 c.888G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8195 c.894C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 p.Ser300Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8217 p.Ser306Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8225 p.Asp308Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8235 p.Leu312Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8258 c.957G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8282 c.981G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8315 c.1014G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8318 c.1017C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8402 p.Asp367Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8421 p.Val374Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8447 c.1146C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8450 c.1149G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8510 c.1209G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8513 c.1212C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8561 c.1260A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8562 c.1261C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8571 c.1270C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8609 c.1308G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8633 c.1332C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8666 c.1365G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8694 c.1393C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8723 c.1422G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8732 c.1431G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8783 c.1482G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8795 c.1494C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8796 p.Ile499Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8981 c.1680G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9003 c.1702C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9017 c.1716C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9101 c.1800A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9284 c.1983T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9323 c.2022C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9371 c.2070G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9401 c.2100G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9413 c.2112G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9449 c.2148C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9452 c.2151G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9557 c.2256G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9560 c.2259C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9566 c.2265C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9585 c.2284T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9590 c.2289T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9593 c.2292G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9602 c.2301T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9604 p.Val768Ala missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9626 c.2325T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9629 c.2328C>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9630 p.Val777Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9656 c.2355C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9659 c.2358C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9668 c.2367C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9689 c.2388G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9707 c.2406G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9716 c.2415T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
fgd1 490863 c.81C>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490869 c.87C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490890 c.108C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490896 c.114C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490905 c.123T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490911 c.129T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490921 p.Gln47Lys missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490929 c.147C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490932 c.150T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490935 c.153C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490945 c.163C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490962 c.180T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490971 c.189A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490974 c.192T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490980 p.Asn66Lys missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490984 p.Leu68Val missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490995 c.213C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490998 c.216T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491007 c.225G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491013 c.231C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491043 c.261T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491049 c.267T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491063 p.Gly94Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491067 c.285C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fgd1 491077 p.Asn99Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491085 c.303T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491091 c.309T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491094 c.312C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491106 c.324T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491121 c.339A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491142 c.360C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491151 c.369G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491154 p.Glu124Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491163 c.381G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491166 c.384G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491181 c.399T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491191 p.Gly137Arg missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491196 c.414A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491203 p.Gln141Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491212 p.Ser144Arg missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491241 p.Asp153Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491604 c.822G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
mshA 574703 c.-645C>T upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 574712 c.-636A>G upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 574718 c.-630A>G upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 574721 c.-627C>G upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 574731 c.-617A>G upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 574738 c.-610_-609delGTinsAC upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 575521 c.174A>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575530 c.183C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575536 c.189T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575539 c.192C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575548 c.201C>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575561 p.Met72Val missense_variant 1.0 isoniazid
ethionamide
mshA 575586 p.Ala80Gly missense_variant 1.0 isoniazid
ethionamide
mshA 575590 c.243T>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575593 c.246G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575596 c.249C>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575629 c.282A>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575633 p.Ala96Thr missense_variant 1.0 isoniazid
ethionamide
mshA 575652 p.Arg102Gln missense_variant 1.0 isoniazid
ethionamide
mshA 575659 c.312A>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575662 c.315C>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575665 c.318G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575686 c.339G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575692 c.345G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575713 c.366G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575732 c.385_387delCTTinsTTG synonymous_variant 1.0 isoniazid
ethionamide
mshA 575737 c.390T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575746 c.399C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575767 c.420G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575770 c.423G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575772 p.Val142Ala missense_variant 1.0 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575821 c.474G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575824 c.477T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575842 c.495G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575848 c.501C>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575872 c.525C>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575878 c.531A>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575884 c.537G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575893 c.546C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575902 c.555C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
mshA 575908 c.561A>G synonymous_variant 1.0 isoniazid
ethionamide
ccsA 620214 c.324C>A synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620245 p.Leu119Met missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620256 c.366C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620257 p.Ile123Val missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620271 c.381C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620283 c.393T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620284 p.Ala132Pro missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620288 p.Arg133Gln missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620290 p.Tyr134Asn missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620295 c.405G>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620314 c.424C>T synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin
amikacin Not assoc w R - Interim
ccsA 620325 c.435G>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620337 c.447C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620358 c.468C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620397 c.507C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620404 c.514C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620622 c.732G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620625 c.735A>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620631 c.741T>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620661 c.771C>T synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620685 c.795G>A synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin
ccsA 620710 p.Val274Ile missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620721 c.831G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620727 c.837G>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620730 c.840C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620733 c.843G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620734 c.844C>A synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620742 c.852G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620748 c.858T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620760 c.870C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620766 c.876C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620773 p.Ile295Val missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620783 p.Ala298Val missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620787 c.897C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
Rv0565c 657300 c.171C>G synonymous_variant 1.0 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 1.0 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657647 c.-179_-177delGTCinsATT upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657678 c.-208A>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657686 c.-216C>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 732308 p.Val127Ile missense_variant 1.0 isoniazid
hadA 732329 p.Leu134Ile missense_variant 1.0 isoniazid
hadA 732346 c.417T>C synonymous_variant 1.0 isoniazid
hadA 732376 c.447T>C synonymous_variant 1.0 isoniazid
hadA 732391 c.462T>A synonymous_variant 1.0 isoniazid
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>T synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734643 c.390G>C synonymous_variant 1.0 rifampicin
nusG 734661 c.408A>C synonymous_variant 1.0 rifampicin
nusG 734664 c.411T>G synonymous_variant 1.0 rifampicin
nusG 734670 c.417G>A synonymous_variant 1.0 rifampicin
nusG 734673 c.420A>G synonymous_variant 1.0 rifampicin
nusG 734680 p.Ala143Ser missense_variant 1.0 rifampicin
nusG 734703 c.450T>C synonymous_variant 1.0 rifampicin
nusG 734709 c.456T>G synonymous_variant 1.0 rifampicin
nusG 734712 c.459G>C synonymous_variant 1.0 rifampicin
nusG 734718 c.465G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734719 p.Ser156Ala missense_variant 1.0 rifampicin
nusG 734722 p.Thr157Ala missense_variant 1.0 rifampicin
nusG 734726 p.Arg158Lys missense_variant 1.0 rifampicin
nusG 734733 c.480T>A synonymous_variant 1.0 rifampicin
nusG 734736 c.483C>G synonymous_variant 1.0 rifampicin
nusG 734754 c.501G>C synonymous_variant 1.0 rifampicin
nusG 734757 c.504T>C synonymous_variant 1.0 rifampicin
nusG 734769 c.516G>A synonymous_variant 1.0 rifampicin
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760172 c.366G>C synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760193 c.387C>G synonymous_variant 1.0 rifampicin
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760202 c.396G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760343 c.537G>C synonymous_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760409 c.603C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760412 c.606C>G synonymous_variant 1.0 rifampicin
rpoB 760415 c.609C>G synonymous_variant 1.0 rifampicin
rpoB 760418 c.612G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760445 c.639C>T synonymous_variant 1.0 rifampicin
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760508 c.702G>C synonymous_variant 1.0 rifampicin
rpoB 760511 c.705G>C synonymous_variant 1.0 rifampicin
rpoB 760577 c.771G>A synonymous_variant 1.0 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760604 c.798G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760607 c.801G>C synonymous_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760920 c.1114C>T synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760994 c.1188G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>T synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>A synonymous_variant 1.0 rifampicin
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761066 c.1260G>C synonymous_variant 1.0 rifampicin
rpoB 761096 c.1290G>C synonymous_variant 1.0 rifampicin
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 1.0 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761408 c.1602G>C synonymous_variant 1.0 rifampicin
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761471 c.1665C>G synonymous_variant 1.0 rifampicin
rpoB 761483 c.1677G>C synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761502 p.Pro566Ala missense_variant 1.0 rifampicin
rpoB 761510 c.1704T>G synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>G synonymous_variant 1.0 rifampicin
rpoB 761603 c.1797C>T synonymous_variant 1.0 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 1.0 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 1.0 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 1.0 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 1.0 rifampicin
rpoB 761822 c.2016C>G synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>A synonymous_variant 1.0 rifampicin
rpoB 761870 p.Asp688Glu missense_variant 1.0 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 1.0 rifampicin
rpoB 761876 c.2070C>A synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 1.0 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761990 c.2184G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 1.0 rifampicin
rpoB 762011 c.2205G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762020 c.2214G>A synonymous_variant 1.0 rifampicin
rpoB 762024 p.Val740Ile missense_variant 1.0 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762071 c.2265C>T synonymous_variant 1.0 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762119 c.2313C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 1.0 rifampicin
rpoB 762224 c.2418C>G synonymous_variant 1.0 rifampicin
rpoB 762236 c.2430G>A synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 1.0 rifampicin
rpoB 762269 c.2463G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762278 c.2472C>G synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 1.0 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762830 c.-540C>T upstream_gene_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762860 c.-510G>T upstream_gene_variant 1.0 rifampicin
rpoB 762899 c.3093G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763050 c.-320C>T upstream_gene_variant 1.0 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>T upstream_gene_variant 1.0 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763124 c.-246C>T upstream_gene_variant 1.0 rifampicin
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763505 c.136C>T synonymous_variant 1.0 rifampicin
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763781 p.Ser138Ala missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763819 c.450G>C synonymous_variant 1.0 rifampicin
rpoC 763916 p.Glu183Gln missense_variant 1.0 rifampicin
rpoC 763945 c.576T>C synonymous_variant 1.0 rifampicin
rpoC 763948 c.579G>C synonymous_variant 1.0 rifampicin
rpoC 763951 c.582G>A synonymous_variant 1.0 rifampicin
rpoC 763987 c.618C>T synonymous_variant 1.0 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 1.0 rifampicin
rpoC 764119 c.750G>A synonymous_variant 1.0 rifampicin
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764140 c.771C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764161 c.792G>C synonymous_variant 1.0 rifampicin
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 1.0 rifampicin
rpoC 764254 c.885G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764269 c.900G>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>T synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764284 c.915G>C synonymous_variant 1.0 rifampicin
rpoC 764317 c.948C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764344 c.975C>T synonymous_variant 1.0 rifampicin
rpoC 764347 c.978G>C synonymous_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764503 c.1134G>C synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>A synonymous_variant 1.0 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>T synonymous_variant 1.0 rifampicin
rpoC 764536 c.1167G>A synonymous_variant 1.0 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764648 c.1279C>A synonymous_variant 1.0 rifampicin
rpoC 764653 c.1284G>C synonymous_variant 1.0 rifampicin
rpoC 764674 c.1305G>A synonymous_variant 1.0 rifampicin
rpoC 764681 c.1312C>T synonymous_variant 1.0 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764800 c.1431G>A synonymous_variant 1.0 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 1.0 rifampicin
rpoC 764833 c.1464A>G synonymous_variant 1.0 rifampicin
rpoC 764872 c.1503A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCTC synonymous_variant 1.0 rifampicin
rpoC 764902 c.1533C>G synonymous_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764918 p.Val517Ile missense_variant 1.0 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765395 c.2026C>T synonymous_variant 1.0 rifampicin
rpoC 765405 p.Leu679Pro missense_variant 1.0 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765430 c.2061G>A synonymous_variant 1.0 rifampicin
rpoC 765445 c.2076G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>G synonymous_variant 1.0 rifampicin
rpoC 765452 p.Ala695Ser missense_variant 1.0 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765496 c.2127C>G synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 1.0 rifampicin
rpoC 765586 c.2217G>A synonymous_variant 1.0 rifampicin
rpoC 765589 c.2220G>C synonymous_variant 1.0 rifampicin
rpoC 765628 c.2259G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765689 c.2320C>T synonymous_variant 1.0 rifampicin
rpoC 765694 c.2325G>C synonymous_variant 1.0 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765748 c.2379C>T synonymous_variant 1.0 rifampicin
rpoC 765752 p.Asp795Ser missense_variant 1.0 rifampicin
rpoC 765757 c.2388C>T synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765790 c.2421C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>A synonymous_variant 1.0 rifampicin
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765910 c.2541G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 1.0 rifampicin
rpoC 765952 c.2583G>C synonymous_variant 1.0 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765997 c.2628T>C synonymous_variant 1.0 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766043 p.Gln892Gly missense_variant 1.0 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766495 c.3126C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766519 c.3150C>A synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 1.0 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 1.0 rifampicin
rpoC 766537 c.3168G>A synonymous_variant 1.0 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 1.0 rifampicin
rpoC 766549 c.3180G>T synonymous_variant 1.0 rifampicin
rpoC 766570 c.3201T>G synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766583 p.Gly1072Ser missense_variant 1.0 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766654 c.3285C>G synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766681 c.3312C>T synonymous_variant 1.0 rifampicin
rpoC 766684 c.3315C>G synonymous_variant 1.0 rifampicin
rpoC 766700 c.3331C>T synonymous_variant 1.0 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766792 c.3423C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766795 c.3426C>T synonymous_variant 1.0 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>A synonymous_variant 1.0 streptomycin
rpsL 781880 c.321C>G synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rplC 800597 c.-212A>G upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 1.0 linezolid
rplC 800609 c.-200G>A upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.94 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 1.0 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 1.0 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 1.0 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 1.0 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 1.0 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 1.0 linezolid
rplC 800783 c.-26C>T upstream_gene_variant 1.0 linezolid
rplC 800797 c.-12T>G upstream_gene_variant 1.0 linezolid
rplC 800799 c.-10G>C upstream_gene_variant 1.0 linezolid
rplC 800800 c.-9G>T upstream_gene_variant 1.0 linezolid
rplC 800801 c.-8A>G upstream_gene_variant 1.0 linezolid
rplC 800817 c.9A>C synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800877 c.69A>C synonymous_variant 1.0 linezolid
rplC 800907 c.99C>G synonymous_variant 1.0 linezolid
rplC 800913 c.105G>C synonymous_variant 1.0 linezolid
rplC 800916 c.108A>T synonymous_variant 1.0 linezolid
rplC 800922 c.114C>G synonymous_variant 1.0 linezolid
rplC 801246 c.438C>G synonymous_variant 1.0 linezolid
rplC 801252 c.444G>C synonymous_variant 1.0 linezolid
rplC 801267 c.459A>T synonymous_variant 1.0 linezolid
rplC 801276 c.468G>C synonymous_variant 1.0 linezolid
rplC 801297 c.489C>T synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801312 c.504G>C synonymous_variant 1.0 linezolid
rplC 801339 c.531T>G synonymous_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801372 c.564G>A synonymous_variant 1.0 linezolid
rplC 801385 c.577C>T synonymous_variant 1.0 linezolid
rplC 801396 c.588T>C synonymous_variant 1.0 linezolid
rplC 801405 c.597T>C synonymous_variant 1.0 linezolid
fbiC 1303441 c.511T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303512 c.582T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303551 c.621G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303578 c.648G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303584 c.654C>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303591 c.661C>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303594 c.664C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303605 c.675C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303611 c.681G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303614 c.684C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303620 c.690C>T synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303632 c.702T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303644 c.714G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303659 c.729T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303661 p.Val244Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303681 c.751_753delTTGinsCTC synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303689 c.759T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303695 c.765T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303704 c.774T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303708 c.778T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303731 c.801A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303732 p.Ser268Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303737 c.807G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303749 c.819G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303752 c.822A>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303768 p.Ser280Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303785 c.855G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303789 p.Ile287Val missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303794 c.864A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303818 c.888C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303825 p.Glu299Lys missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303836 c.906G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303884 c.954T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303890 c.960G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303902 c.972G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303905 c.975G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303911 c.981G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303923 c.993C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303998 c.1068T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304001 c.1071C>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304004 c.1074A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304008 c.1078T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304022 c.1092T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304031 c.1101C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304049 c.1119T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304079 c.1149A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304091 c.1161C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304092 p.Met388Leu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304112 c.1182G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304120 p.Lys397Arg missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304124 c.1194C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304127 c.1197A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304142 c.1212G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304163 c.1233G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304164 p.Gly412Arg missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304172 c.1242G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304174 p.Val415Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304178 c.1248G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304181 c.1251G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304184 c.1254G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304200 p.Leu424Phe missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304205 c.1275C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304208 c.1278C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304217 p.Asn429Lys missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304598 c.1668C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304625 c.1695C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304628 c.1698G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304649 c.1719C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304658 c.1728C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304661 c.1731C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304675 p.Gly582Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304679 c.1749G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304691 c.1761G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>C synonymous_variant 0.96 pretomanid
delamanid
clofazimine
fbiC 1304703 c.1773C>T synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304715 c.1785G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304724 c.1794A>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304742 c.1812T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304751 c.1821C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304784 c.1854T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304790 c.1860C>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304799 c.1869G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304808 c.1878C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304809 p.Ser627Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304832 c.1902C>T synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304893 p.Gly655Ser missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304901 c.1971C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305096 c.2166T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305099 c.2169T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305111 c.2181C>T synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1305117 c.2187T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305120 c.2190G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305126 c.2196T>C synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1305150 c.2220C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305154 c.2224T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305159 c.2229G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305162 c.2232C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305165 c.2235G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305186 c.2256C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305192 c.2262C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305195 c.2265T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305204 c.2274C>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364889 c.477A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364898 c.486C>T synonymous_variant 1.0 pyrazinamide
sigE 1364913 c.501C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
inhA 1673595 c.-607A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673596 c.-606A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673607 c.-595T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673609 c.-593G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673616 c.-586A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673619 c.-583T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673679 c.-523T>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673682 c.-520G>C upstream_gene_variant 1.0 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1673685 c.-517C>T upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 1.0 isoniazid
ethionamide
inhA 1674546 c.345T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674561 c.360C>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674570 c.369G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674573 c.372G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674576 c.375T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674579 c.378G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674582 c.381T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674585 c.384T>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674588 c.387G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674594 c.393C>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674601 c.400C>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674609 c.408G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674618 c.417C>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674620 p.Pro140Arg missense_variant 1.0 isoniazid
ethionamide
inhA 1674624 c.423A>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674627 c.426T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674675 c.474C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674718 c.517A>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674729 c.528G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674756 c.555T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674762 c.561T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674774 c.573A>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674777 c.576C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 1.0 isoniazid
ethionamide
rpsA 1833589 c.48A>T synonymous_variant 1.0 pyrazinamide
rpsA 1833593 p.Ser18Thr missense_variant 1.0 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833610 c.69C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833718 c.177C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833754 c.213G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833850 c.309C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834024 c.483G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834174 c.633C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834336 c.795C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834339 c.798C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834369 c.828C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834375 c.834G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834495 c.954G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834615 c.1074C>T synonymous_variant 1.0 pyrazinamide
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 1.0 linezolid
tsnR 1853393 c.-213C>T upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
tsnR 1853408 c.-198C>T upstream_gene_variant 1.0 linezolid
tlyA 1917929 c.-11T>C upstream_gene_variant 1.0 capreomycin
tlyA 1917934 c.-6T>G upstream_gene_variant 1.0 capreomycin
tlyA 1917937 c.-3G>A upstream_gene_variant 1.0 capreomycin
tlyA 1917938 c.-2G>A upstream_gene_variant 1.0 capreomycin
tlyA 1917948 c.9A>G synonymous_variant 1.0 capreomycin
tlyA 1917965 p.Ala9Val missense_variant 1.0 capreomycin
bacA 2064192 c.537A>G synonymous_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
bacA 2065002 c.-274C>G upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
katG 2155680 c.432G>C synonymous_variant 1.0 isoniazid
katG 2155691 c.421T>C synonymous_variant 1.0 isoniazid
katG 2155704 c.408C>G synonymous_variant 1.0 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2518252 c.138C>T synonymous_variant 1.0 isoniazid
kasA 2518279 c.165T>C synonymous_variant 1.0 isoniazid
kasA 2518283 p.Ala57Pro missense_variant 1.0 isoniazid
kasA 2518297 c.183C>T synonymous_variant 1.0 isoniazid
kasA 2518300 c.186T>C synonymous_variant 1.0 isoniazid
kasA 2518312 c.198T>C synonymous_variant 1.0 isoniazid
kasA 2518318 c.204C>G synonymous_variant 1.0 isoniazid
kasA 2518323 p.Ser70Asn missense_variant 1.0 isoniazid
kasA 2518334 c.220_222delCGAinsAGG synonymous_variant 1.0 isoniazid
kasA 2518339 c.225C>G synonymous_variant 1.0 isoniazid
kasA 2518348 c.234A>G synonymous_variant 1.0 isoniazid
kasA 2518360 c.246C>T synonymous_variant 1.0 isoniazid
kasA 2518374 p.Gly87Ala missense_variant 1.0 isoniazid
kasA 2518393 p.Gln93His missense_variant 1.0 isoniazid
kasA 2518396 c.282A>C synonymous_variant 1.0 isoniazid
kasA 2518408 c.294C>G synonymous_variant 1.0 isoniazid
kasA 2518475 c.361A>C synonymous_variant 1.0 isoniazid
kasA 2518480 c.366T>C synonymous_variant 1.0 isoniazid
kasA 2518492 c.378C>T synonymous_variant 1.0 isoniazid
kasA 2518504 c.390T>C synonymous_variant 1.0 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 1.0 isoniazid
kasA 2518513 c.399C>G synonymous_variant 1.0 isoniazid
kasA 2518519 c.405G>C synonymous_variant 1.0 isoniazid
kasA 2518534 c.420G>C synonymous_variant 1.0 isoniazid
kasA 2518537 c.423C>G synonymous_variant 1.0 isoniazid
kasA 2518561 c.447T>C synonymous_variant 1.0 isoniazid
kasA 2518567 c.453G>T synonymous_variant 1.0 isoniazid
kasA 2518573 c.459G>C synonymous_variant 1.0 isoniazid
kasA 2518574 p.Ile154Val missense_variant 1.0 isoniazid
kasA 2518588 c.474T>C synonymous_variant 1.0 isoniazid
kasA 2518591 c.477G>C synonymous_variant 1.0 isoniazid
kasA 2518618 c.504G>C synonymous_variant 1.0 isoniazid
kasA 2518633 c.519G>C synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518645 c.531G>C synonymous_variant 1.0 isoniazid
kasA 2518648 c.534C>T synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518681 c.567C>T synonymous_variant 1.0 isoniazid
kasA 2518684 c.570C>A synonymous_variant 1.0 isoniazid
kasA 2518711 c.597A>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>T synonymous_variant 1.0 isoniazid
kasA 2518735 c.621C>A synonymous_variant 1.0 isoniazid
kasA 2518744 c.630C>T synonymous_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518756 c.642G>C synonymous_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518789 c.675G>T synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>G synonymous_variant 1.0 isoniazid
kasA 2518798 c.684G>C synonymous_variant 1.0 isoniazid
kasA 2518816 c.702C>T synonymous_variant 1.0 isoniazid
kasA 2518822 c.708C>T synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518855 c.741C>G synonymous_variant 1.0 isoniazid
kasA 2518856 p.Ile248Leu missense_variant 1.0 isoniazid
kasA 2518864 c.750G>C synonymous_variant 1.0 isoniazid
kasA 2518885 c.771T>C synonymous_variant 1.0 isoniazid
kasA 2518894 c.780G>A synonymous_variant 1.0 isoniazid
kasA 2518903 c.789C>T synonymous_variant 1.0 isoniazid
kasA 2518906 c.792A>G synonymous_variant 1.0 isoniazid
kasA 2518910 c.796C>T synonymous_variant 1.0 isoniazid
kasA 2518939 c.825T>C synonymous_variant 1.0 isoniazid
kasA 2518942 c.828T>C synonymous_variant 1.0 isoniazid
kasA 2518960 c.846C>G synonymous_variant 1.0 isoniazid
kasA 2518963 c.849T>C synonymous_variant 1.0 isoniazid
ahpC 2726324 c.132A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726336 c.144G>C synonymous_variant 1.0 isoniazid
ahpC 2726348 c.156T>C synonymous_variant 1.0 isoniazid
ahpC 2726354 c.162G>C synonymous_variant 1.0 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726366 c.174G>C synonymous_variant 1.0 isoniazid
ahpC 2726378 c.186T>G synonymous_variant 1.0 isoniazid
ahpC 2726393 c.201G>C synonymous_variant 1.0 isoniazid
ahpC 2726397 p.Ser69Gly missense_variant 1.0 isoniazid
ahpC 2726408 c.216T>C synonymous_variant 1.0 isoniazid
ahpC 2726430 p.Ala80Thr missense_variant 1.0 isoniazid
ahpC 2726441 c.249G>C synonymous_variant 1.0 isoniazid
ahpC 2726444 c.252G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726447 c.255T>C synonymous_variant 1.0 isoniazid
ahpC 2726450 c.258G>C synonymous_variant 1.0 isoniazid
ahpC 2726453 c.261T>C synonymous_variant 1.0 isoniazid
ahpC 2726467 p.Ala92Val missense_variant 1.0 isoniazid
ahpC 2726471 c.279T>C synonymous_variant 1.0 isoniazid
ahpC 2726483 c.291T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
folC 2747371 c.228C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747386 c.213C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747389 c.210G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747398 c.201C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747404 c.195G>C synonymous_variant 1.0 para-aminosalicylic_acid
Rv2477c 2783188 c.855G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783215 c.828G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783238 c.804_805insAC frameshift_variant 1.0 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2783241 p.Glu268Lys missense_variant 1.0 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2783243 c.798_799delGA frameshift_variant 1.0 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2783247 c.796T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783248 c.795G>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783289 p.Leu252Ile missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783373 p.Glu224Gln missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783410 c.633G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783415 c.628C>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783416 c.627C>T synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783419 c.624G>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783428 c.615C>T synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783432 p.Ser204Ala missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783437 c.606G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783467 c.576G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783476 c.567C>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2681 2996987 c.249A>G synonymous_variant 1.0 capreomycin
Rv2681 2996996 c.258C>T synonymous_variant 1.0 capreomycin
Rv2681 2997014 c.276T>C synonymous_variant 1.0 capreomycin
Rv2681 2997017 p.Asp93Glu missense_variant 1.0 capreomycin
Rv2681 2997021 p.Leu95Ala missense_variant 1.0 capreomycin
Rv2681 2997028 p.Val97Ala missense_variant 1.0 capreomycin
Rv2681 2997033 p.Ala99Gln missense_variant 1.0 capreomycin
Rv2681 2997071 c.333C>T synonymous_variant 1.0 capreomycin
Rv2681 2997092 c.354T>C synonymous_variant 1.0 capreomycin
Rv2681 2997098 c.360C>G synonymous_variant 1.0 capreomycin
Rv2681 2997104 c.366C>G synonymous_variant 0.92 capreomycin
Rv2681 2997116 c.378T>C synonymous_variant 1.0 capreomycin
Rv2681 2997122 c.384A>G synonymous_variant 1.0 capreomycin Not assoc w R - Interim
Rv2681 2997126 p.Pro130Ser missense_variant 1.0 capreomycin
Rv2681 2997134 c.396A>C synonymous_variant 1.0 capreomycin
Rv2752c 3065556 c.636G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065594 c.598C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065595 p.Leu199Phe missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066522 c.-331C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066549 c.-358T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066573 c.-382G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066579 c.-388A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066592 c.-401A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066612 c.-421G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066618 c.-427A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066630 c.-439G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066633 c.-442T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067832 c.114C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067838 c.108C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067847 p.Pro33Ser missense_variant 1.0 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073962 c.510G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073997 c.475C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074045 c.427C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 1.0 para-aminosalicylic_acid
thyA 3074091 c.381C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074123 p.Asp117Asn missense_variant 1.0 para-aminosalicylic_acid
thyA 3074127 c.345G>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074130 c.342G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074133 c.339C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074151 c.321G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074157 c.315C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074160 c.312A>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074163 c.309T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074172 c.300G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074184 c.288A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 1.0 para-aminosalicylic_acid
thyA 3074208 c.264C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074217 c.255T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074297 c.175C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074307 c.165A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074313 c.159A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074334 c.138T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074349 c.123T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074355 c.117G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074360 c.112T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074361 c.111T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074367 c.103_105delCGCinsAGG synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074370 p.Met34Ile missense_variant 1.0 para-aminosalicylic_acid
thyA 3074391 c.81C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074397 c.75A>C synonymous_variant 1.0 para-aminosalicylic_acid
lpqB 3623468 c.1443T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3623471 c.1440C>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623489 c.1422C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3623492 c.1419T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623510 c.1401C>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623531 p.Gly460Asp missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623549 c.1362C>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623561 c.1350T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623564 c.1347C>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623570 c.1341A>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623573 c.1338T>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623576 c.1335T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623580 p.Asn444Thr missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623588 c.1323G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623594 c.1317C>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623600 c.1311C>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623605 p.Ala436Ser missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623782 p.Val377Ile missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623789 c.1122T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623792 c.1119G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623799 p.Glu371Val missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624368 c.543C>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624389 c.522C>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3625161 c.-251T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625177 c.-267C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625345 c.-435T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625366 c.-456C>A upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625381 c.-471T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625384 c.-474G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625387 c.-477T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625396 c.-486G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625405 p.Gln403Glu missense_variant 1.0 rifampicin
bedaquiline
mtrB 3625408 p.Glu402His missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625414 c.-504C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625419 c.1195C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625420 p.Asp398Glu missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625426 c.-516G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625432 c.-522G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625459 c.-549C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625465 c.-555T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625471 c.-561C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625474 c.-564G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625480 p.Asn378Lys missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625486 c.-576G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625489 c.-579A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625497 c.1117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625510 c.-600T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625518 c.-608T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625522 c.-612C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625537 c.-627T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625543 c.-633G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625569 c.1045T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625572 p.Thr348Ser missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625579 c.-669A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625588 c.-678G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625594 c.-684T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625602 c.-692T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625612 c.-702G>T upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625615 c.-705G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625624 c.-714C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625630 c.-720C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625633 c.981C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625648 c.-738T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625684 c.-774G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625747 c.-837G>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625750 c.864G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 1.0 rifampicin Uncertain significance
bedaquiline
lpqB 3625762 c.-852A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625798 c.-888G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625803 c.-893C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625804 c.-896_-894delAGGinsCGA upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625819 c.795G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625822 c.-912C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625837 c.-927C>A upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625840 c.-930A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625852 c.762A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625864 c.-954T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625891 c.-981G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625903 c.-993G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625906 c.-996G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625909 c.-999T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625915 c.699G>A synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626344 c.270G>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626357 p.Thr86Asn missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626359 c.255C>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626362 c.252A>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626372 p.Ile81Thr missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626383 c.231G>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626386 c.228G>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626390 p.Arg75Lys missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626394 p.Val74Leu missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626395 c.219G>A synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626400 p.Ile72Val missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626407 c.207C>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626410 c.204T>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626413 c.201T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626437 c.177T>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626440 c.174C>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626443 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626455 c.159C>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626776 c.-163A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626780 c.-167T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626786 c.564A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626792 c.558G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626795 c.-182C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626798 c.-185T>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626866 c.-253T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626885 c.-272A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626890 c.-277T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626912 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626930 c.-317A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626936 c.-323C>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626939 p.Glu137Asp missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626942 c.-329A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626945 c.-332C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626954 c.-341C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626963 c.387G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626972 c.-359A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626981 c.-368C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626990 c.-377G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627002 c.-389G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627011 c.-398T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627032 c.-419G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627056 c.294C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627071 c.-458G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627083 c.-470G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627104 c.-491C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627140 c.-527G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627155 c.-542C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627182 c.-569T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627187 c.163T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627188 c.-577_-575delTTAinsCTG upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627203 c.-590C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627227 c.123T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
fbiA 3640269 c.-274A>C upstream_gene_variant 1.0 pretomanid
delamanid
clofazimine
fbiA 3640282 c.-261C>G upstream_gene_variant 1.0 pretomanid
delamanid
clofazimine
fbiA 3640298 c.-245A>G upstream_gene_variant 1.0 pretomanid
delamanid
clofazimine
fbiA 3640318 c.-225A>T upstream_gene_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3641900 c.366G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3641909 c.375T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3641924 c.390A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3641925 p.Thr131Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3641928 c.394T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3641948 c.414G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3641951 c.417G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3641957 c.423C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3641966 c.432C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3641969 c.435C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3641975 c.441C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3641976 p.Ile148Val missense_variant 1.0 pretomanid
delamanid
clofazimine
alr 3840272 c.1149C>G synonymous_variant 1.0 cycloserine
alr 3840275 c.1146T>G synonymous_variant 1.0 cycloserine
alr 3840293 c.1128T>G synonymous_variant 1.0 cycloserine
alr 3840296 c.1125G>C synonymous_variant 1.0 cycloserine
alr 3840317 c.1104G>C synonymous_variant 1.0 cycloserine
alr 3840328 c.1093T>C synonymous_variant 1.0 cycloserine
alr 3840332 c.1089G>C synonymous_variant 1.0 cycloserine
alr 3840341 c.1080C>T synonymous_variant 1.0 cycloserine
alr 3840353 c.1068T>C synonymous_variant 1.0 cycloserine
alr 3840356 p.Leu355Val missense_variant 1.0 cycloserine
alr 3840362 c.1059G>C synonymous_variant 1.0 cycloserine
rpoA 3877587 c.921A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877593 c.915C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877602 c.906C>T synonymous_variant 1.0 rifampicin
rpoA 3877613 p.Ile299Val missense_variant 1.0 rifampicin
rpoA 3877656 c.852T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877659 c.849G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877830 c.678C>T synonymous_variant 1.0 rifampicin
rpoA 3877836 c.672A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>G synonymous_variant 0.95 rifampicin
rpoA 3877886 c.622C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877896 c.612G>C synonymous_variant 1.0 rifampicin
rpoA 3877899 p.Ser203Thr missense_variant 1.0 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 1.0 rifampicin
rpoA 3877926 c.582G>C synonymous_variant 1.0 rifampicin
rpoA 3877929 c.579C>T synonymous_variant 1.0 rifampicin
rpoA 3877950 c.558C>T synonymous_variant 1.0 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878022 c.486T>C synonymous_variant 1.0 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 1.0 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 1.0 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 1.0 rifampicin
rpoA 3878043 c.465G>T synonymous_variant 1.0 rifampicin
rpoA 3878058 c.450G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878061 c.447G>C synonymous_variant 1.0 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 1.0 rifampicin
rpoA 3878085 c.423G>A synonymous_variant 1.0 rifampicin
rpoA 3878097 c.411G>A synonymous_variant 1.0 rifampicin
rpoA 3878100 c.408C>G synonymous_variant 1.0 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878126 c.382C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878127 c.381G>C synonymous_variant 1.0 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 1.0 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 1.0 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878202 c.306G>C synonymous_variant 1.0 rifampicin
rpoA 3878211 c.297G>A synonymous_variant 1.0 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 1.0 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 1.0 rifampicin
rpoA 3878283 p.Glu75Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878364 c.144A>T synonymous_variant 1.0 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.91 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 1.0 rifampicin
rpoA 3878376 c.132G>A synonymous_variant 1.0 rifampicin
rpoA 3878381 c.127C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878391 c.117T>A synonymous_variant 1.0 rifampicin
rpoA 3878403 c.105C>T synonymous_variant 1.0 rifampicin
rpoA 3878406 c.102G>T synonymous_variant 1.0 rifampicin
rpoA 3878412 c.96C>T synonymous_variant 1.0 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 1.0 rifampicin
rpoA 3879016 c.-509A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879043 c.-536C>G upstream_gene_variant 1.0 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879100 c.-593G>A upstream_gene_variant 1.0 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879148 c.-641G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879235 c.-728C>T upstream_gene_variant 1.0 rifampicin
rpoA 3879238 c.-731C>T upstream_gene_variant 1.0 rifampicin
ddn 3986636 c.-208C>A upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986637 c.-207C>T upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986648 c.-196C>G upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986975 c.132T>C synonymous_variant 1.0 pretomanid
delamanid
ddn 3986984 c.141G>T synonymous_variant 1.0 pretomanid
delamanid
ddn 3987020 c.177G>A synonymous_variant 1.0 pretomanid
delamanid
ddn 3987028 p.Asn62Ser missense_variant 1.0 pretomanid
delamanid
ddn 3987035 c.192C>G synonymous_variant 0.93 pretomanid
delamanid
ddn 3987053 c.210T>C synonymous_variant 1.0 pretomanid
delamanid
ddn 3987055 p.Gly71Asp missense_variant 1.0 pretomanid
delamanid
ddn 3987062 c.219C>G synonymous_variant 1.0 pretomanid
delamanid
ddn 3987065 c.222T>C synonymous_variant 1.0 pretomanid
delamanid
ddn 3987071 c.228G>C synonymous_variant 1.0 pretomanid
delamanid
ddn 3987089 c.246G>C synonymous_variant 1.0 pretomanid
delamanid
ddn 3987092 p.Glu83Asp missense_variant 1.0 pretomanid
delamanid Uncertain significance
clpC1 4038271 p.Pro812Ala missense_variant 1.0 pyrazinamide
clpC1 4038272 c.2433T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038308 c.2397G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038314 c.2391T>G synonymous_variant 1.0 pyrazinamide
clpC1 4038335 c.2370C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038344 c.2361G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038350 c.2355C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038383 c.2322G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038407 c.2298G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 1.0 pyrazinamide
clpC1 4038508 c.2197C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038519 p.Arg729Gln missense_variant 1.0 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 1.0 pyrazinamide
clpC1 4038533 c.2172C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038536 c.2169C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038587 c.2118C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038800 c.1905C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038838 c.1867C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038839 c.1866G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038902 c.1803C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038980 c.1725C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038995 c.1710G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039009 c.1696C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039090 c.1615C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039337 c.1368A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039352 c.1353C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039391 c.1314T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039484 c.1221T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039493 c.1212C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039514 c.1191C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039541 c.1164C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039552 c.1153C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039553 c.1152C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039574 p.Ala377Ser missense_variant 1.0 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039586 c.1119G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039601 c.1104G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039693 c.1012C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039733 c.972G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039754 c.951G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039763 c.942C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039766 c.939T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039868 c.837C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039942 c.763C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039946 c.759A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039996 p.Glu237Gln missense_variant 1.0 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.92 pyrazinamide
clpC1 4040048 c.657C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040091 c.613_614delTCinsAG synonymous_variant 1.0 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040594 c.111G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.91 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040636 c.69C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
embC 4239044 c.-819G>C upstream_gene_variant 1.0 ethambutol
embC 4239625 c.-238A>G upstream_gene_variant 1.0 ethambutol
embC 4239638 c.-225C>A upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239641 c.-222G>C upstream_gene_variant 1.0 ethambutol
embC 4239661 c.-202A>C upstream_gene_variant 1.0 ethambutol
embC 4239663 c.-200C>G upstream_gene_variant 1.0 ethambutol
embC 4239671 c.-192C>G upstream_gene_variant 1.0 ethambutol
embC 4239674 c.-189C>G upstream_gene_variant 1.0 ethambutol
embC 4240150 c.288A>G synonymous_variant 1.0 ethambutol
embC 4240151 p.Ser97Pro missense_variant 1.0 ethambutol
embC 4240726 c.864G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240741 c.879C>T synonymous_variant 1.0 ethambutol
embC 4240777 c.915G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 1.0 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240795 c.933C>G synonymous_variant 1.0 ethambutol
embC 4240801 c.939C>T synonymous_variant 1.0 ethambutol
embC 4240831 c.969T>C synonymous_variant 1.0 ethambutol
embC 4240858 c.996G>A synonymous_variant 1.0 ethambutol
embC 4240859 p.Leu333Met missense_variant 1.0 ethambutol
embC 4240867 c.1005T>G synonymous_variant 1.0 ethambutol
embC 4240918 c.1056G>C synonymous_variant 1.0 ethambutol
embC 4240921 c.1059C>G synonymous_variant 1.0 ethambutol
embC 4240924 c.1062C>G synonymous_variant 1.0 ethambutol
embC 4240934 p.Val358Leu missense_variant 1.0 ethambutol
embC 4240945 c.1083T>C synonymous_variant 1.0 ethambutol
embC 4241017 c.1155T>C synonymous_variant 0.9 ethambutol
embC 4241039 p.Asp393Asn missense_variant 1.0 ethambutol
embC 4241095 c.1233C>T synonymous_variant 1.0 ethambutol
embC 4241107 c.1245G>C synonymous_variant 1.0 ethambutol
embC 4241140 c.1278A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241153 p.Ile431Leu missense_variant 1.0 ethambutol
embA 4244165 c.933T>G synonymous_variant 1.0 ethambutol
embA 4244170 p.Gln313Arg missense_variant 1.0 ethambutol
embA 4244178 p.Ala316Ser missense_variant 1.0 ethambutol
embA 4244603 c.1371G>A synonymous_variant 1.0 ethambutol
embA 4244612 c.1380C>G synonymous_variant 1.0 ethambutol
embA 4244615 c.1383G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244616 p.Ala462Ser missense_variant 1.0 ethambutol
embA 4244619 c.1387T>C synonymous_variant 1.0 ethambutol
embA 4244645 c.1413T>C synonymous_variant 1.0 ethambutol
embA 4244648 c.1416G>C synonymous_variant 1.0 ethambutol
embA 4244649 p.Asp473Ser missense_variant 1.0 ethambutol
embA 4244663 c.1431C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244669 c.1437G>C synonymous_variant 1.0 ethambutol
embA 4244675 c.1443A>G synonymous_variant 1.0 ethambutol
embA 4244681 c.1449A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244684 c.1452C>G synonymous_variant 1.0 ethambutol
embA 4244702 c.1470C>G synonymous_variant 1.0 ethambutol
embA 4244705 c.1473G>C synonymous_variant 1.0 ethambutol
embA 4244708 c.1476C>G synonymous_variant 1.0 ethambutol
embA 4244714 c.1482C>G synonymous_variant 1.0 ethambutol
embA 4244792 c.1560G>C synonymous_variant 1.0 ethambutol
embA 4244802 p.Leu524Met missense_variant 0.92 ethambutol
embA 4244805 c.1573C>T synonymous_variant 0.86 ethambutol
embA 4244808 p.Phe526Leu missense_variant 1.0 ethambutol
embA 4244822 c.1590G>A synonymous_variant 1.0 ethambutol
embA 4244823 p.Val531Met missense_variant 1.0 ethambutol
embA 4244856 p.Ala542Pro missense_variant 1.0 ethambutol
embA 4244885 c.1653A>G synonymous_variant 1.0 ethambutol
embA 4244897 c.1665T>G synonymous_variant 1.0 ethambutol
embA 4244903 c.1671G>C synonymous_variant 1.0 ethambutol
embA 4245149 c.1917C>G synonymous_variant 1.0 ethambutol
embA 4245182 c.1950T>C synonymous_variant 1.0 ethambutol
embA 4245186 p.Thr652Ala missense_variant 1.0 ethambutol
embA 4245194 c.1962G>A synonymous_variant 1.0 ethambutol
embA 4245195 p.Ile655Val missense_variant 1.0 ethambutol
embA 4245200 c.1968C>G synonymous_variant 1.0 ethambutol
embA 4245206 c.1974A>C synonymous_variant 1.0 ethambutol
embA 4245207 c.1975T>C synonymous_variant 1.0 ethambutol
embA 4245215 c.1983A>C synonymous_variant 1.0 ethambutol
embA 4245224 c.1992T>C synonymous_variant 1.0 ethambutol
embA 4245248 c.2016G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245257 c.2025A>G synonymous_variant 1.0 ethambutol
embA 4245263 c.2031A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245345 p.Met705Leu missense_variant 1.0 ethambutol
embA 4245355 p.Ala708Gly missense_variant 1.0 ethambutol
embA 4245368 c.2136T>C synonymous_variant 1.0 ethambutol
embA 4245375 p.Leu715Met missense_variant 1.0 ethambutol
embA 4245402 p.Thr724Ala missense_variant 1.0 ethambutol
embA 4245409 c.2178_2179delCA frameshift_variant 1.0 ethambutol Uncertain significance
embA 4245413 p.Ser727Arg missense_variant 1.0 ethambutol
embA 4245414 c.2182_2183insAT frameshift_variant 1.0 ethambutol Uncertain significance
embA 4245424 c.2192_2193insGCCCAG disruptive_inframe_insertion 1.0 ethambutol
embA 4245431 c.2199T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245434 c.2202G>C synonymous_variant 1.0 ethambutol
embA 4245458 c.2226G>A synonymous_variant 1.0 ethambutol
embA 4245464 c.2232C>T synonymous_variant 1.0 ethambutol
embA 4245473 c.2241C>T synonymous_variant 1.0 ethambutol
embA 4245488 c.2256G>C synonymous_variant 1.0 ethambutol
embA 4245497 c.2265C>T synonymous_variant 1.0 ethambutol
embA 4245501 p.Ala757Thr missense_variant 1.0 ethambutol
embA 4245510 p.Pro760Ser missense_variant 1.0 ethambutol
embA 4245524 c.2292G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245620 c.-894T>C upstream_gene_variant 1.0 ethambutol
embB 4245623 c.-891G>A upstream_gene_variant 1.0 ethambutol
embB 4245662 c.-852G>C upstream_gene_variant 1.0 ethambutol
embA 4245674 c.2442A>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245677 c.-837G>C upstream_gene_variant 1.0 ethambutol
embB 4245683 c.-831C>T upstream_gene_variant 1.0 ethambutol
embA 4245693 p.Ile821Val missense_variant 1.0 ethambutol
embB 4245714 c.-800C>T upstream_gene_variant 1.0 ethambutol
embB 4245725 c.-789A>G upstream_gene_variant 1.0 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 1.0 ethambutol
embB 4245734 c.-780G>C upstream_gene_variant 1.0 ethambutol
embB 4245737 c.-777A>T upstream_gene_variant 1.0 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 1.0 ethambutol
embA 4245772 p.Asn847Thr missense_variant 1.0 ethambutol
embB 4245803 c.-711C>T upstream_gene_variant 1.0 ethambutol
embB 4245806 c.-708G>A upstream_gene_variant 1.0 ethambutol
embB 4245807 c.-707_-705delTTAinsCTG upstream_gene_variant 1.0 ethambutol
embB 4245812 c.-702G>T upstream_gene_variant 1.0 ethambutol
embA 4245813 p.Pro861Ala missense_variant 1.0 ethambutol
embA 4245822 p.Pro864Ala missense_variant 1.0 ethambutol
embB 4245839 c.-675G>C upstream_gene_variant 1.0 ethambutol
embB 4245857 c.-657C>G upstream_gene_variant 1.0 ethambutol
embA 4245869 c.2637C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245875 c.-639G>A upstream_gene_variant 1.0 ethambutol
embB 4245887 c.-627T>C upstream_gene_variant 1.0 ethambutol
embA 4245891 p.Ile887Val missense_variant 1.0 ethambutol
embB 4245905 c.-609C>T upstream_gene_variant 1.0 ethambutol
embB 4245906 c.-608C>T upstream_gene_variant 1.0 ethambutol
embB 4245923 c.-591C>A upstream_gene_variant 1.0 ethambutol
embA 4245930 p.Gly900Arg missense_variant 1.0 ethambutol
embA 4245935 c.2703G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245942 p.Arg904Gly missense_variant 1.0 ethambutol
embB 4245953 c.-561A>G upstream_gene_variant 1.0 ethambutol
embB 4245956 c.-558G>C upstream_gene_variant 1.0 ethambutol
embA 4245965 c.2733A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245968 c.-546T>C upstream_gene_variant 1.0 ethambutol
embA 4245978 p.Ile916Leu missense_variant 1.0 ethambutol
embB 4245983 c.-531A>G upstream_gene_variant 1.0 ethambutol
embB 4245992 c.-522C>G upstream_gene_variant 1.0 ethambutol
embB 4246004 c.-510T>C upstream_gene_variant 1.0 ethambutol
embB 4246005 c.-509C>T upstream_gene_variant 1.0 ethambutol
embB 4246013 c.-501T>C upstream_gene_variant 1.0 ethambutol
embA 4246020 p.Ala930Thr missense_variant 1.0 ethambutol
embA 4246028 c.2796G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246070 c.-444G>C upstream_gene_variant 1.0 ethambutol
embB 4246082 c.-432T>C upstream_gene_variant 1.0 ethambutol
embB 4246109 c.-405C>G upstream_gene_variant 1.0 ethambutol
embB 4246115 c.-399T>C upstream_gene_variant 1.0 ethambutol
embA 4246128 p.Ser966Thr missense_variant 1.0 ethambutol
embA 4246138 p.Arg969Gln missense_variant 1.0 ethambutol
embB 4246140 c.-374T>C upstream_gene_variant 1.0 ethambutol
embB 4246148 c.-366G>C upstream_gene_variant 1.0 ethambutol
embB 4246151 c.-363A>C upstream_gene_variant 1.0 ethambutol
embA 4246152 p.Ala974Arg missense_variant 1.0 ethambutol
embB 4246172 c.-342C>T upstream_gene_variant 1.0 ethambutol
embB 4246184 c.-330A>C upstream_gene_variant 1.0 ethambutol
embB 4246205 c.-309A>G upstream_gene_variant 1.0 ethambutol
embB 4246211 c.-303T>C upstream_gene_variant 1.0 ethambutol
embB 4246217 c.-297G>A upstream_gene_variant 1.0 ethambutol
embA 4246220 c.2988T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246223 c.-291C>T upstream_gene_variant 1.0 ethambutol
embA 4246227 p.Ile999Val missense_variant 1.0 ethambutol
embA 4246235 c.3003G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246244 c.-270G>A upstream_gene_variant 1.0 ethambutol
embA 4246254 p.Leu1008Met missense_variant 1.0 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 1.0 ethambutol
embB 4246307 c.-207G>C upstream_gene_variant 1.0 ethambutol
embB 4246316 c.-198T>C upstream_gene_variant 1.0 ethambutol
embB 4246346 c.-168C>G upstream_gene_variant 1.0 ethambutol
embA 4246359 p.Ala1043Ser missense_variant 1.0 ethambutol
embB 4246373 c.-141T>C upstream_gene_variant 1.0 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 1.0 ethambutol
embA 4246398 p.Ser1056Thr missense_variant 1.0 ethambutol
embA 4246413 p.His1061Tyr missense_variant 1.0 ethambutol
embB 4247440 c.927C>G synonymous_variant 1.0 ethambutol
embB 4247470 c.957T>C synonymous_variant 1.0 ethambutol
embB 4247497 c.984T>C synonymous_variant 1.0 ethambutol
embB 4247500 c.987C>G synonymous_variant 1.0 ethambutol
embB 4247512 c.999T>C synonymous_variant 1.0 ethambutol
embB 4247566 c.1053C>G synonymous_variant 1.0 ethambutol
embB 4247579 p.Ala356Phe missense_variant 1.0 ethambutol
embB 4247608 c.1095G>C synonymous_variant 1.0 ethambutol
embB 4247611 c.1098G>C synonymous_variant 1.0 ethambutol
embB 4247632 c.1119C>G synonymous_variant 1.0 ethambutol
embB 4247645 p.Glu378Thr missense_variant 1.0 ethambutol
embB 4247648 p.Ala379Ser missense_variant 1.0 ethambutol
embB 4247657 p.Pro382Ala missense_variant 1.0 ethambutol
embB 4247671 c.1158G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247679 p.Met389Thr missense_variant 1.0 ethambutol
embB 4247684 c.1171T>C synonymous_variant 1.0 ethambutol
embB 4247722 c.1209G>C synonymous_variant 1.0 ethambutol
embB 4247725 c.1212G>C synonymous_variant 1.0 ethambutol
embB 4247728 c.1215G>A synonymous_variant 1.0 ethambutol
embB 4247743 c.1230C>G synonymous_variant 1.0 ethambutol
embB 4247761 c.1248T>C synonymous_variant 1.0 ethambutol
embB 4247779 c.1266C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247785 c.1272G>C synonymous_variant 1.0 ethambutol
embB 4247800 c.1287A>C synonymous_variant 1.0 ethambutol
embB 4247830 c.1317A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247858 c.1345C>T synonymous_variant 1.0 ethambutol
embB 4247899 p.Met462Ile missense_variant 1.0 ethambutol
embB 4247911 p.Leu466Phe missense_variant 1.0 ethambutol
embB 4247915 p.Arg468Lys missense_variant 1.0 ethambutol
embB 4247920 c.1407T>C synonymous_variant 1.0 ethambutol
embB 4247923 c.1410T>C synonymous_variant 1.0 ethambutol
embB 4247932 c.1419C>G synonymous_variant 1.0 ethambutol
embB 4247948 p.Val479Leu missense_variant 1.0 ethambutol Uncertain significance
embB 4247975 p.Val488Ile missense_variant 1.0 ethambutol Uncertain significance
embB 4247989 c.1476G>C synonymous_variant 1.0 ethambutol
embB 4248001 c.1488C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248007 c.1494C>G synonymous_variant 1.0 ethambutol
embB 4248130 c.1617G>C synonymous_variant 1.0 ethambutol
embB 4248142 c.1629T>C synonymous_variant 1.0 ethambutol
embB 4248143 c.1630T>C synonymous_variant 1.0 ethambutol
embB 4248169 c.1656C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248175 c.1662G>A synonymous_variant 1.0 ethambutol
embB 4248178 c.1665C>T synonymous_variant 1.0 ethambutol
embB 4248206 p.Ser565Gly missense_variant 1.0 ethambutol Uncertain significance
embB 4248214 c.1701C>G synonymous_variant 1.0 ethambutol
embB 4248217 c.1704C>G synonymous_variant 1.0 ethambutol
embB 4248220 c.1707A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248233 c.1720C>T synonymous_variant 1.0 ethambutol
embB 4248252 p.Gly580Ala missense_variant 1.0 ethambutol
embB 4248266 c.1753C>T synonymous_variant 1.0 ethambutol
embB 4248277 c.1764G>C synonymous_variant 1.0 ethambutol
embB 4248280 c.1767C>G synonymous_variant 1.0 ethambutol
embB 4248316 c.1803C>G synonymous_variant 1.0 ethambutol
embB 4248319 c.1806A>G synonymous_variant 1.0 ethambutol
embB 4248334 c.1821C>G synonymous_variant 1.0 ethambutol
embB 4248349 c.1836G>A synonymous_variant 1.0 ethambutol
embB 4248358 c.1845C>G synonymous_variant 1.0 ethambutol
embB 4248361 c.1848A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248379 c.1866G>A synonymous_variant 1.0 ethambutol
embB 4248407 p.Leu632Val missense_variant 1.0 ethambutol
embB 4248412 p.Phe633Leu missense_variant 1.0 ethambutol
embB 4248416 p.Leu635Met missense_variant 1.0 ethambutol
embB 4248424 c.1911G>A synonymous_variant 1.0 ethambutol
embB 4248430 c.1917T>C synonymous_variant 1.0 ethambutol
embB 4248448 c.1935C>T synonymous_variant 1.0 ethambutol
embB 4248457 c.1944T>C synonymous_variant 1.0 ethambutol
embB 4248472 c.1959T>C synonymous_variant 1.0 ethambutol
embB 4248496 c.1983G>C synonymous_variant 1.0 ethambutol
embB 4248504 p.Asp664Ala missense_variant 1.0 ethambutol
embB 4248508 c.1995G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4267529 c.1308T>C synonymous_variant 1.0 ethambutol
aftB 4267535 c.1302A>G synonymous_variant 1.0 ethambutol
aftB 4267556 c.1281G>C synonymous_variant 1.0 ethambutol
aftB 4267574 c.1263G>C synonymous_variant 1.0 ethambutol
aftB 4267580 c.1257G>A synonymous_variant 1.0 ethambutol
aftB 4267592 c.1245C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4267622 p.Ser405Thr missense_variant 1.0 ethambutol
aftB 4267634 p.Arg401His missense_variant 1.0 ethambutol
aftB 4267637 c.1200C>G synonymous_variant 1.0 ethambutol
aftB 4267649 c.1188T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4267667 c.1170A>G synonymous_variant 1.0 ethambutol
aftB 4269660 c.-824C>A upstream_gene_variant 1.0 ethambutol
ubiA 4269663 p.Met57Val missense_variant 1.0 ethambutol
aftB 4269669 c.-833G>T upstream_gene_variant 1.0 ethambutol
ubiA 4269676 p.Ser53Thr missense_variant 1.0 ethambutol
aftB 4269678 c.-842C>G upstream_gene_variant 1.0 ethambutol
ubiA 4269688 p.Val49Ala missense_variant 1.0 ethambutol Uncertain significance
ubiA 4269690 c.144C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim