TB-Profiler result

Run: ERR4188322
Summary

Run ID: ERR4188322

Sample name:

Date: 2024-04-13T23:57:36.074924

Number of reads: 333560

Percentage reads mapped: 31.1

Median coverage: 9.0

Strain: lineage4.6.4;lineage4.9

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.6.4 Euro-American None 0.07
lineage4 Euro-American None 0.75
lineage4.9 Euro-American (H37Rv-like) None 0.88
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.His312Arg Mutation from literature
p.Tyr384Asn Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin tlyA c.1dupG Assoc w R
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fbiC c.751_753delTTGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.859_861delATCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.895_897delGAAinsAG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1270_1272delCTGinsTC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fbiC 1303681 c.751_753delTTGinsCC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGT frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303825 c.895_897delGAAinsAG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304200 c.1270_1272delCTGinsTC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
tlyA 1917939 c.1dupG frameshift_variant 1.0 capreomycin Assoc w R
embB 4247448 p.His312Arg missense_variant 1.0 ethambutol Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 1.0 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 802 c.802C>T synonymous_variant 1.0 isoniazid
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 810 c.810C>G synonymous_variant 1.0 isoniazid
dnaA 813 c.813C>T synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 1.0 isoniazid
dnaA 927 c.927G>A synonymous_variant 1.0 isoniazid
dnaA 1179 c.1179G>C synonymous_variant 1.0 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 1.0 isoniazid
gyrB 5377 c.138T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6086 p.Thr283Pro missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6097 c.858G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6121 c.882C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6299 c.1060C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6313 c.-989C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7595 c.294C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7619 c.318C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7622 c.321C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7766 c.465C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7769 c.468C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7838 c.537C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7850 c.549C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8084 c.783G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8090 c.789C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8105 c.804G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8189 c.888G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8195 c.894C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 p.Ser300Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8217 p.Ser306Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8225 p.Asp308Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsGG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8258 c.957G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8282 c.981G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8315 c.1014G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8318 c.1017C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 c.1039_1041delGCGinsTC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8402 p.Asp367Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8421 c.1120_1122delGTGinsAC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8447 c.1146C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8450 c.1149G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8510 c.1209G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8513 c.1212C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8561 c.1260A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8562 c.1261C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8571 c.1270C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8609 c.1308G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8633 c.1332C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8666 c.1365G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8694 c.1393C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8723 c.1422G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8732 c.1431G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8783 c.1482G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8795 c.1494C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8796 p.Ile499Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9003 c.1702C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9017 c.1716C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9101 c.1800A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9284 c.1983T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9323 c.2022C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9371 c.2070G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9401 c.2100G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9413 c.2112G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9449 c.2148C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9452 c.2151G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9557 c.2256G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9560 c.2259C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9566 c.2265C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9585 c.2284T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9590 c.2289T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9593 c.2292G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9602 c.2301T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9604 p.Val768Ala missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9626 c.2325T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9629 c.2328C>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9630 p.Val777Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9656 c.2355C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9659 c.2358C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9668 c.2367C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9689 c.2388G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9707 c.2406G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9716 c.2415T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
fgd1 490863 c.81C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490869 c.87C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490935 c.153C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490945 c.163C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490984 p.Leu68Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490995 c.213C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491063 p.Gly94Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491067 c.285C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fgd1 491077 p.Asn99Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491085 c.303T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491142 c.360C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491151 c.369G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491154 p.Glu124Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491163 c.381G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491604 c.822G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 574703 c.-645C>T upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574712 c.-636A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574718 c.-630A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574721 c.-627C>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574731 c.-617A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574738 c.-610_-609delGTinsAC upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575521 c.174A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575530 c.183C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575539 c.192C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575548 c.201C>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 1.0 ethionamide
isoniazid
mshA 575586 p.Ala80Gly missense_variant 1.0 ethionamide
isoniazid
mshA 575590 c.243T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575593 c.246G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575596 c.249C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575629 c.282A>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575633 c.286_288delGCAinsAG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575652 p.Arg102Gln missense_variant 1.0 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575662 c.315C>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575665 c.318G>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575686 c.339G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575692 c.345G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575732 c.385_387delCTTinsTG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575737 c.390T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575767 c.420G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575770 c.423G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575772 p.Val142Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575824 c.477T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575848 c.501C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575872 c.525C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575878 c.531A>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575902 c.555C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575908 c.561A>G synonymous_variant 1.0 ethionamide
isoniazid
ccsA 620214 c.324C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620245 p.Leu119Met missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620257 p.Ile123Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620271 c.381C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620290 p.Tyr134Asn missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620314 c.424C>T synonymous_variant 1.0 capreomycin
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620325 c.435G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620337 c.447C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620358 c.468C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620397 c.507C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620404 c.514C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620622 c.732G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>T synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620685 c.795G>A synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin
kanamycin Not assoc w R - Interim
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620727 c.837G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620760 c.870C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620766 c.876C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620773 p.Ile295Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 657300 c.171C>G synonymous_variant 1.0 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 1.0 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657647 c.-179_-177delGTCinsAT upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657678 c.-208A>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657686 c.-216C>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 732308 p.Val127Ile missense_variant 1.0 isoniazid
hadA 732329 c.400_402delCTCinsAT frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
hadA 732346 c.417T>C synonymous_variant 1.0 isoniazid
hadA 732376 c.447T>C synonymous_variant 1.0 isoniazid
hadA 732391 c.462T>A synonymous_variant 1.0 isoniazid
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>T synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734643 c.390G>C synonymous_variant 1.0 rifampicin
nusG 734661 c.408A>C synonymous_variant 1.0 rifampicin
nusG 734664 c.411T>G synonymous_variant 1.0 rifampicin
nusG 734670 c.417G>A synonymous_variant 1.0 rifampicin
nusG 734673 c.420A>G synonymous_variant 1.0 rifampicin
nusG 734680 p.Ala143Ser missense_variant 1.0 rifampicin
nusG 734703 c.450T>C synonymous_variant 1.0 rifampicin
nusG 734709 c.456T>G synonymous_variant 1.0 rifampicin
nusG 734712 c.459G>C synonymous_variant 1.0 rifampicin
nusG 734718 c.465G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734719 p.Ser156Ala missense_variant 1.0 rifampicin
nusG 734722 p.Thr157Ala missense_variant 1.0 rifampicin
nusG 734726 p.Arg158Lys missense_variant 1.0 rifampicin
nusG 734733 c.480T>A synonymous_variant 1.0 rifampicin
nusG 734736 c.483C>G synonymous_variant 1.0 rifampicin
nusG 734754 c.501G>C synonymous_variant 1.0 rifampicin
nusG 734757 c.504T>C synonymous_variant 1.0 rifampicin
nusG 734769 c.516G>A synonymous_variant 1.0 rifampicin
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760172 c.366G>C synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760193 c.387C>G synonymous_variant 1.0 rifampicin
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760202 c.396G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760343 c.537G>C synonymous_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760409 c.603C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760412 c.606C>G synonymous_variant 1.0 rifampicin
rpoB 760415 c.609C>G synonymous_variant 1.0 rifampicin
rpoB 760418 c.612G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760445 c.639C>T synonymous_variant 1.0 rifampicin
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760508 c.702G>C synonymous_variant 1.0 rifampicin
rpoB 760511 c.705G>C synonymous_variant 1.0 rifampicin
rpoB 760577 c.771G>A synonymous_variant 1.0 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760604 c.798G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760607 c.801G>C synonymous_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760920 c.1114C>T synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760994 c.1188G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>T synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>A synonymous_variant 1.0 rifampicin
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761066 c.1260G>C synonymous_variant 1.0 rifampicin
rpoB 761096 c.1290G>C synonymous_variant 1.0 rifampicin
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 1.0 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761408 c.1602G>C synonymous_variant 1.0 rifampicin
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761471 c.1665C>G synonymous_variant 1.0 rifampicin
rpoB 761483 c.1677G>C synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761502 p.Pro566Ala missense_variant 1.0 rifampicin
rpoB 761510 c.1704T>G synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 1.0 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>G synonymous_variant 1.0 rifampicin
rpoB 761603 c.1797C>T synonymous_variant 1.0 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 1.0 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 1.0 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 1.0 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 1.0 rifampicin
rpoB 761822 c.2016C>G synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>A synonymous_variant 1.0 rifampicin
rpoB 761870 p.Asp688Glu missense_variant 1.0 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 1.0 rifampicin
rpoB 761876 c.2070C>A synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 1.0 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761990 c.2184G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 1.0 rifampicin
rpoB 762011 c.2205G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762020 c.2214G>A synonymous_variant 1.0 rifampicin
rpoB 762024 c.2218_2220delGTGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762071 c.2265C>T synonymous_variant 1.0 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762119 c.2313C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 1.0 rifampicin
rpoB 762224 c.2418C>G synonymous_variant 1.0 rifampicin
rpoB 762236 c.2430G>A synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 1.0 rifampicin
rpoB 762269 c.2463G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762278 c.2472C>G synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 c.3007_3009delATGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762830 c.-540C>T upstream_gene_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762860 c.-510G>T upstream_gene_variant 1.0 rifampicin
rpoB 762899 c.3093G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763050 c.-320C>T upstream_gene_variant 1.0 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>T upstream_gene_variant 1.0 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763124 c.-246C>T upstream_gene_variant 1.0 rifampicin
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763505 c.136C>T synonymous_variant 1.0 rifampicin
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763781 p.Ser138Ala missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763819 c.450G>C synonymous_variant 1.0 rifampicin
rpoC 763916 p.Glu183Gln missense_variant 1.0 rifampicin
rpoC 763945 c.576T>C synonymous_variant 1.0 rifampicin
rpoC 763948 c.579G>C synonymous_variant 1.0 rifampicin
rpoC 763951 c.582G>A synonymous_variant 1.0 rifampicin
rpoC 763987 c.618C>T synonymous_variant 1.0 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 1.0 rifampicin
rpoC 764119 c.750G>A synonymous_variant 1.0 rifampicin
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764140 c.771C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764161 c.792G>C synonymous_variant 1.0 rifampicin
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 1.0 rifampicin
rpoC 764254 c.885G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764269 c.900G>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>T synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764284 c.915G>C synonymous_variant 1.0 rifampicin
rpoC 764317 c.948C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764344 c.975C>T synonymous_variant 1.0 rifampicin
rpoC 764347 c.978G>C synonymous_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764503 c.1134G>C synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>A synonymous_variant 1.0 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>T synonymous_variant 1.0 rifampicin
rpoC 764536 c.1167G>A synonymous_variant 1.0 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764648 c.1279C>A synonymous_variant 1.0 rifampicin
rpoC 764653 c.1284G>C synonymous_variant 1.0 rifampicin
rpoC 764674 c.1305G>A synonymous_variant 1.0 rifampicin
rpoC 764681 c.1312C>T synonymous_variant 1.0 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764800 c.1431G>A synonymous_variant 1.0 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 1.0 rifampicin
rpoC 764833 c.1464A>G synonymous_variant 1.0 rifampicin
rpoC 764872 c.1503A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764902 c.1533C>G synonymous_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764918 c.1549_1551delGTGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765395 c.2026C>T synonymous_variant 1.0 rifampicin
rpoC 765405 p.Leu679Pro missense_variant 1.0 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765430 c.2061G>A synonymous_variant 1.0 rifampicin
rpoC 765445 c.2076G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>G synonymous_variant 1.0 rifampicin
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765496 c.2127C>G synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 1.0 rifampicin
rpoC 765586 c.2217G>A synonymous_variant 1.0 rifampicin
rpoC 765589 c.2220G>C synonymous_variant 1.0 rifampicin
rpoC 765628 c.2259G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765689 c.2320C>T synonymous_variant 1.0 rifampicin
rpoC 765694 c.2325G>C synonymous_variant 1.0 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765748 c.2379C>T synonymous_variant 1.0 rifampicin
rpoC 765752 p.Asp795Ser missense_variant 1.0 rifampicin
rpoC 765757 c.2388C>T synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765790 c.2421C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>A synonymous_variant 1.0 rifampicin
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765910 c.2541G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 1.0 rifampicin
rpoC 765952 c.2583G>C synonymous_variant 1.0 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765997 c.2628T>C synonymous_variant 1.0 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766043 p.Gln892Gly missense_variant 1.0 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766495 c.3126C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766519 c.3150C>A synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 1.0 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 1.0 rifampicin
rpoC 766537 c.3168G>A synonymous_variant 1.0 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 1.0 rifampicin
rpoC 766549 c.3180G>T synonymous_variant 1.0 rifampicin
rpoC 766570 c.3201T>G synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766654 c.3285C>G synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766681 c.3312C>T synonymous_variant 1.0 rifampicin
rpoC 766684 c.3315C>G synonymous_variant 1.0 rifampicin
rpoC 766700 c.3331C>T synonymous_variant 1.0 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766792 c.3423C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766795 c.3426C>T synonymous_variant 1.0 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>A synonymous_variant 1.0 streptomycin
rpsL 781880 c.321C>G synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rplC 800597 c.-212A>G upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 1.0 linezolid
rplC 800609 c.-200G>A upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.94 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 1.0 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 1.0 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 1.0 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 1.0 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 1.0 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 1.0 linezolid
rplC 800783 c.-26C>T upstream_gene_variant 1.0 linezolid
rplC 800797 c.-12T>G upstream_gene_variant 1.0 linezolid
rplC 800799 c.-10G>C upstream_gene_variant 1.0 linezolid
rplC 800800 c.-9G>T upstream_gene_variant 1.0 linezolid
rplC 800801 c.-8A>G upstream_gene_variant 1.0 linezolid
rplC 800817 c.9A>C synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800877 c.69A>C synonymous_variant 1.0 linezolid
rplC 800907 c.99C>G synonymous_variant 1.0 linezolid
rplC 800913 c.105G>C synonymous_variant 1.0 linezolid
rplC 800916 c.108A>T synonymous_variant 1.0 linezolid
rplC 800922 c.114C>G synonymous_variant 1.0 linezolid
rplC 801246 c.438C>G synonymous_variant 1.0 linezolid
rplC 801252 c.444G>C synonymous_variant 1.0 linezolid
rplC 801267 c.459A>T synonymous_variant 1.0 linezolid
rplC 801276 c.468G>C synonymous_variant 1.0 linezolid
rplC 801297 c.489C>T synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801312 c.504G>C synonymous_variant 1.0 linezolid
rplC 801339 c.531T>G synonymous_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801372 c.564G>A synonymous_variant 1.0 linezolid
rplC 801385 c.577C>T synonymous_variant 1.0 linezolid
rplC 801396 c.588T>C synonymous_variant 1.0 linezolid
rplC 801405 c.597T>C synonymous_variant 1.0 linezolid
fbiC 1303441 c.511T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303551 c.621G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303578 c.648G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303591 c.661C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303594 c.664C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303620 c.690C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303632 c.702T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303644 c.714G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303661 p.Val244Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303689 c.759T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303768 p.Ser280Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303836 c.906G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303890 c.960G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303902 c.972G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303911 c.981G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303923 c.993C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303998 c.1068T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304001 c.1071C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304004 c.1074A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304049 c.1119T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304079 c.1149A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304091 c.1161C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304112 c.1182G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304120 p.Lys397Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304124 c.1194C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304142 c.1212G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304163 c.1233G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304164 p.Gly412Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304174 p.Val415Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304178 c.1248G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304181 c.1251G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304205 c.1275C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304208 c.1278C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304217 p.Asn429Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304598 c.1668C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304628 c.1698G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304649 c.1719C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304661 c.1731C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304679 c.1749G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304715 c.1785G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304799 c.1869G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304809 p.Ser627Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304901 c.1971C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305111 c.2181C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305117 c.2187T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305120 c.2190G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305150 c.2220C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305154 c.2224T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305159 c.2229G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305162 c.2232C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305165 c.2235G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305186 c.2256C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305192 c.2262C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305204 c.2274C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364889 c.477A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364898 c.486C>T synonymous_variant 1.0 pyrazinamide
sigE 1364913 c.501C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
inhA 1673595 c.-607A>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673596 p.Lys53Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673609 p.Gly57Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1673616 c.-586A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673619 c.-583T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673679 c.-523T>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673682 c.-520G>C upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673685 c.-517C>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674561 c.360C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674570 c.369G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674573 c.372G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674579 c.378G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674588 c.387G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674594 c.393C>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674601 c.400C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674609 c.408G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674618 c.417C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674620 p.Pro140Arg missense_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674675 c.474C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674718 c.517A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674762 c.561T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674774 c.573A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674777 c.576C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
rpsA 1833589 c.48A>T synonymous_variant 1.0 pyrazinamide
rpsA 1833593 c.52_54delTCTinsAC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1833604 c.63C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833610 c.69C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833718 c.177C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833754 c.213G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833850 c.309C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834024 c.483G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834174 c.633C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834336 c.795C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834339 c.798C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834369 c.828C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834375 c.834G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834495 c.954G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834615 c.1074C>T synonymous_variant 1.0 pyrazinamide
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 1.0 linezolid
tsnR 1853393 c.-213C>T upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
tsnR 1853408 c.-198C>T upstream_gene_variant 1.0 linezolid
tlyA 1917929 c.-11T>C upstream_gene_variant 1.0 capreomycin
tlyA 1917934 c.-6T>G upstream_gene_variant 1.0 capreomycin
tlyA 1917937 c.-3G>A upstream_gene_variant 1.0 capreomycin
tlyA 1917938 c.-2G>A upstream_gene_variant 1.0 capreomycin
tlyA 1917948 c.9A>G synonymous_variant 1.0 capreomycin
tlyA 1917965 p.Ala9Val missense_variant 1.0 capreomycin
bacA 2064192 c.537A>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2065002 c.-274C>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
katG 2155680 c.432G>C synonymous_variant 1.0 isoniazid
katG 2155691 c.421T>C synonymous_variant 1.0 isoniazid
katG 2155704 c.408C>G synonymous_variant 1.0 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2518252 c.138C>T synonymous_variant 1.0 isoniazid
kasA 2518279 c.165T>C synonymous_variant 1.0 isoniazid
kasA 2518283 p.Ala57Pro missense_variant 1.0 isoniazid
kasA 2518297 c.183C>T synonymous_variant 1.0 isoniazid
kasA 2518300 c.186T>C synonymous_variant 1.0 isoniazid
kasA 2518312 c.198T>C synonymous_variant 1.0 isoniazid
kasA 2518318 c.204C>G synonymous_variant 1.0 isoniazid
kasA 2518323 p.Ser70Asn missense_variant 1.0 isoniazid
kasA 2518334 c.220_222delCGAinsAG frameshift_variant&synonymous_variant 1.0 isoniazid
kasA 2518339 c.225C>G synonymous_variant 1.0 isoniazid
kasA 2518348 c.234A>G synonymous_variant 1.0 isoniazid
kasA 2518360 c.246C>T synonymous_variant 1.0 isoniazid
kasA 2518374 p.Gly87Ala missense_variant 1.0 isoniazid
kasA 2518393 p.Gln93His missense_variant 1.0 isoniazid
kasA 2518396 c.282A>C synonymous_variant 1.0 isoniazid
kasA 2518408 c.294C>G synonymous_variant 1.0 isoniazid
kasA 2518475 c.361A>C synonymous_variant 1.0 isoniazid
kasA 2518480 c.366T>C synonymous_variant 1.0 isoniazid
kasA 2518492 c.378C>T synonymous_variant 1.0 isoniazid
kasA 2518504 c.390T>C synonymous_variant 1.0 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 1.0 isoniazid
kasA 2518513 c.399C>G synonymous_variant 1.0 isoniazid
kasA 2518519 c.405G>C synonymous_variant 1.0 isoniazid
kasA 2518534 c.420G>C synonymous_variant 1.0 isoniazid
kasA 2518537 c.423C>G synonymous_variant 1.0 isoniazid
kasA 2518561 c.447T>C synonymous_variant 1.0 isoniazid
kasA 2518567 c.453G>T synonymous_variant 1.0 isoniazid
kasA 2518573 c.459G>C synonymous_variant 1.0 isoniazid
kasA 2518574 c.460_462delATCinsGG frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518588 c.474T>C synonymous_variant 1.0 isoniazid
kasA 2518591 c.477G>C synonymous_variant 1.0 isoniazid
kasA 2518618 c.504G>C synonymous_variant 1.0 isoniazid
kasA 2518633 c.519G>C synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518645 c.531G>C synonymous_variant 1.0 isoniazid
kasA 2518648 c.534C>T synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518681 c.567C>T synonymous_variant 1.0 isoniazid
kasA 2518684 c.570C>A synonymous_variant 1.0 isoniazid
kasA 2518711 c.597A>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>T synonymous_variant 1.0 isoniazid
kasA 2518735 c.621C>A synonymous_variant 1.0 isoniazid
kasA 2518744 c.630C>T synonymous_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518756 c.642G>C synonymous_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518789 c.675G>T synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>G synonymous_variant 1.0 isoniazid
kasA 2518798 c.684G>C synonymous_variant 1.0 isoniazid
kasA 2518816 c.702C>T synonymous_variant 1.0 isoniazid
kasA 2518822 c.708C>T synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518855 c.741C>G synonymous_variant 1.0 isoniazid
kasA 2518856 p.Ile248Leu missense_variant 1.0 isoniazid
kasA 2518864 c.750G>C synonymous_variant 1.0 isoniazid
kasA 2518885 c.771T>C synonymous_variant 1.0 isoniazid
kasA 2518894 c.780G>A synonymous_variant 1.0 isoniazid
kasA 2518903 c.789C>T synonymous_variant 1.0 isoniazid
kasA 2518906 c.792A>G synonymous_variant 1.0 isoniazid
kasA 2518910 c.796C>T synonymous_variant 1.0 isoniazid
kasA 2518939 c.825T>C synonymous_variant 1.0 isoniazid
kasA 2518942 c.828T>C synonymous_variant 1.0 isoniazid
kasA 2518960 c.846C>G synonymous_variant 1.0 isoniazid
kasA 2518963 c.849T>C synonymous_variant 1.0 isoniazid
ahpC 2726324 c.132A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726336 c.144G>C synonymous_variant 1.0 isoniazid
ahpC 2726348 c.156T>C synonymous_variant 1.0 isoniazid
ahpC 2726354 c.162G>C synonymous_variant 1.0 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726366 c.174G>C synonymous_variant 1.0 isoniazid
ahpC 2726378 c.186T>G synonymous_variant 1.0 isoniazid
ahpC 2726393 c.201G>C synonymous_variant 1.0 isoniazid
ahpC 2726397 p.Ser69Gly missense_variant 1.0 isoniazid
ahpC 2726408 c.216T>C synonymous_variant 1.0 isoniazid
ahpC 2726430 c.238_240delGCCinsAG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
ahpC 2726441 c.249G>C synonymous_variant 1.0 isoniazid
ahpC 2726444 c.252G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726447 c.255T>C synonymous_variant 1.0 isoniazid
ahpC 2726450 c.258G>C synonymous_variant 1.0 isoniazid
ahpC 2726453 c.261T>C synonymous_variant 1.0 isoniazid
ahpC 2726467 p.Ala92Val missense_variant 1.0 isoniazid
ahpC 2726471 c.279T>C synonymous_variant 1.0 isoniazid
ahpC 2726483 c.291T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
folC 2747371 c.228C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747386 c.213C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747389 c.210G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747398 c.201C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747404 c.195G>C synonymous_variant 1.0 para-aminosalicylic_acid
Rv2477c 2783188 c.855G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783215 c.828G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783238 c.804_805insAC frameshift_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783241 p.Glu268Lys missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783243 c.798_799delGA frameshift_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783247 c.796T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783248 c.795G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783289 p.Leu252Ile missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783373 p.Glu224Gln missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783410 c.633G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783415 c.628C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783416 c.627C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783419 c.624G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783428 c.615C>T synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783432 p.Ser204Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783437 c.606G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783476 c.567C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2681 2996987 c.249A>G synonymous_variant 1.0 capreomycin
Rv2681 2996996 c.258C>T synonymous_variant 1.0 capreomycin
Rv2681 2997014 c.276T>C synonymous_variant 1.0 capreomycin
Rv2681 2997017 p.Asp93Glu missense_variant 1.0 capreomycin
Rv2681 2997021 p.Leu95Ala missense_variant 1.0 capreomycin
Rv2681 2997028 p.Val97Ala missense_variant 1.0 capreomycin
Rv2681 2997033 p.Ala99Gln missense_variant 1.0 capreomycin
Rv2681 2997071 c.333C>T synonymous_variant 1.0 capreomycin
Rv2681 2997092 c.354T>C synonymous_variant 1.0 capreomycin
Rv2681 2997098 c.360C>G synonymous_variant 1.0 capreomycin
Rv2681 2997104 c.366C>G synonymous_variant 0.92 capreomycin
Rv2681 2997116 c.378T>C synonymous_variant 1.0 capreomycin
Rv2681 2997122 c.384A>G synonymous_variant 1.0 capreomycin Not assoc w R - Interim
Rv2681 2997126 c.388_390delCCAinsTG frameshift_variant&stop_gained 1.0 capreomycin Uncertain significance
Rv2681 2997134 c.396A>C synonymous_variant 1.0 capreomycin
Rv2752c 3065556 c.636G>A synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065594 c.598C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065595 p.Leu199Phe missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066522 c.-331C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066549 c.-358T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066573 c.-382G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066579 c.-388A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066592 c.-401A>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066612 c.-421G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066618 c.-427A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066630 c.-439G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066633 c.-442T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067832 c.114C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067838 c.108C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067847 c.97_99delCCCinsTG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073962 c.510G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073997 c.475C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074045 c.427C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 1.0 para-aminosalicylic_acid
thyA 3074091 c.381C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074123 p.Asp117Asn missense_variant 1.0 para-aminosalicylic_acid
thyA 3074127 c.345G>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074130 c.342G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074133 c.339C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074151 c.321G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074157 c.315C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074160 c.312A>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074163 c.309T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074172 c.300G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074184 c.288A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 1.0 para-aminosalicylic_acid
thyA 3074208 c.264C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074217 c.255T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074297 c.175C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074307 c.165A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074313 c.159A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074334 c.138T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074349 c.123T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074355 c.117G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074360 c.112T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074361 c.111T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074367 c.103_105delCGCinsAG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyA 3074370 p.Met34Ile missense_variant 1.0 para-aminosalicylic_acid
thyA 3074391 c.81C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074397 c.75A>C synonymous_variant 1.0 para-aminosalicylic_acid
lpqB 3623468 c.1443T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623471 c.1440C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623489 c.1422C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623492 c.1419T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623510 c.1401C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623531 p.Gly460Asp missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623549 c.1362C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623561 c.1350T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623564 c.1347C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623570 c.1341A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623573 c.1338T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623576 c.1335T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623580 p.Asn444Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623588 c.1323G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623594 c.1317C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623600 c.1311C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623605 p.Ala436Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623782 p.Val377Ile missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623789 c.1122T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623792 c.1119G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623799 p.Glu371Val missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624368 c.543C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624389 c.522C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3625161 c.-251T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625177 c.-267C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625366 c.-456C>A upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625381 c.-471T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625384 c.-474G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625387 c.-477T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625396 c.-486G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625405 c.1207_1209delCAGinsGA frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625408 c.1204_1206delGAGinsCC frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625414 c.-504C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625419 c.1195C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625420 p.Asp398Glu missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625426 c.-516G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625432 c.-522G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625459 c.-549C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625465 c.-555T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625471 c.-561C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625474 c.-564G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625480 p.Asn378Lys missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625486 c.-576G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625489 c.-579A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625497 c.1117T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625510 c.-600T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625518 c.-608T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625522 c.-612C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625537 c.-627T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625543 c.-633G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625572 p.Thr348Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625579 c.-669A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625588 c.-678G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625612 c.-702G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625615 c.-705G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625630 c.-720C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625633 c.981C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625648 c.-738T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625684 c.-774G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625747 c.-837G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625750 c.864G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3625762 c.-852A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625798 c.-888G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625803 c.-893C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625804 c.808_810delAGGinsCA frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625819 c.795G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625822 c.-912C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625837 c.-927C>A upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625840 c.-930A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625891 c.-981G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625903 c.-993G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625906 c.-996G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625909 c.-999T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625915 c.699G>A synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626344 c.270G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626357 p.Thr86Asn missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626359 c.255C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626362 c.252A>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626372 p.Ile81Thr missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626383 c.231G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626386 c.228G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626390 p.Arg75Lys missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626394 p.Val74Leu missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626395 c.219G>A synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626400 p.Ile72Val missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626407 c.207C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626410 c.204T>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626413 c.201T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626437 c.177T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626440 c.174C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626443 c.171T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626455 c.159C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626776 c.-163A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626795 c.-182C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626798 c.-185T>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626866 c.-253T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626885 c.-272A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626912 c.438T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626930 c.-317A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626936 c.-323C>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626939 p.Glu137Asp missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626942 c.-329A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626945 c.-332C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626954 c.-341C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626963 c.387G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626972 c.-359A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626981 c.-368C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626990 c.-377G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627002 c.-389G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627011 c.-398T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627032 c.-419G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627056 c.294C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627071 c.-458G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627140 c.-527G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627155 c.-542C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627187 c.163T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627188 c.160_162delTTAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627203 c.-590C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627227 c.123T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
fbiA 3640269 c.-274A>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640282 c.-261C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640298 c.-245A>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640318 c.-225A>T upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641900 c.366G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641909 c.375T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641924 c.390A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641925 p.Thr131Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641928 c.394T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641948 c.414G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641951 c.417G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641957 c.423C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641966 c.432C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641969 c.435C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641975 c.441C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641976 p.Ile148Val missense_variant 1.0 clofazimine
pretomanid
delamanid
alr 3840272 c.1149C>G synonymous_variant 1.0 cycloserine
alr 3840275 c.1146T>G synonymous_variant 1.0 cycloserine
alr 3840293 c.1128T>G synonymous_variant 1.0 cycloserine
alr 3840296 c.1125G>C synonymous_variant 1.0 cycloserine
alr 3840317 c.1104G>C synonymous_variant 1.0 cycloserine
alr 3840328 c.1093T>C synonymous_variant 1.0 cycloserine
alr 3840332 c.1089G>C synonymous_variant 1.0 cycloserine
alr 3840341 c.1080C>T synonymous_variant 1.0 cycloserine
alr 3840353 c.1068T>C synonymous_variant 1.0 cycloserine
alr 3840356 c.1063_1065delCTTinsGC frameshift_variant&missense_variant 1.0 cycloserine
alr 3840362 c.1059G>C synonymous_variant 1.0 cycloserine
rpoA 3877587 c.921A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877593 c.915C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877602 c.906C>T synonymous_variant 1.0 rifampicin
rpoA 3877613 p.Ile299Val missense_variant 1.0 rifampicin
rpoA 3877656 c.852T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877659 c.849G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877830 c.678C>T synonymous_variant 1.0 rifampicin
rpoA 3877836 c.672A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>G synonymous_variant 0.95 rifampicin
rpoA 3877886 c.622C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877896 c.612G>C synonymous_variant 1.0 rifampicin
rpoA 3877899 p.Ser203Thr missense_variant 1.0 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 1.0 rifampicin
rpoA 3877926 c.582G>C synonymous_variant 1.0 rifampicin
rpoA 3877929 c.579C>T synonymous_variant 1.0 rifampicin
rpoA 3877950 c.558C>T synonymous_variant 1.0 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878022 c.486T>C synonymous_variant 1.0 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 1.0 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 1.0 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 1.0 rifampicin
rpoA 3878043 c.465G>T synonymous_variant 1.0 rifampicin
rpoA 3878058 c.450G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878061 c.447G>C synonymous_variant 1.0 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 1.0 rifampicin
rpoA 3878085 c.423G>A synonymous_variant 1.0 rifampicin
rpoA 3878097 c.411G>A synonymous_variant 1.0 rifampicin
rpoA 3878100 c.408C>G synonymous_variant 1.0 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878126 c.382C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878127 c.381G>C synonymous_variant 1.0 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 1.0 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 1.0 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878202 c.306G>C synonymous_variant 1.0 rifampicin
rpoA 3878211 c.297G>A synonymous_variant 1.0 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 1.0 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 1.0 rifampicin
rpoA 3878283 p.Glu75Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878364 c.144A>T synonymous_variant 1.0 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.91 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 1.0 rifampicin
rpoA 3878376 c.132G>A synonymous_variant 1.0 rifampicin
rpoA 3878381 c.127C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878391 c.117T>A synonymous_variant 1.0 rifampicin
rpoA 3878403 c.105C>T synonymous_variant 1.0 rifampicin
rpoA 3878406 c.102G>T synonymous_variant 1.0 rifampicin
rpoA 3878412 c.96C>T synonymous_variant 1.0 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 1.0 rifampicin
rpoA 3879016 c.-509A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879043 c.-536C>G upstream_gene_variant 1.0 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879100 c.-593G>A upstream_gene_variant 1.0 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879148 c.-641G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879235 c.-728C>T upstream_gene_variant 1.0 rifampicin
rpoA 3879238 c.-731C>T upstream_gene_variant 1.0 rifampicin
ddn 3986636 c.-208C>A upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986637 c.-207C>T upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986648 c.-196C>G upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986975 c.132T>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3986984 c.141G>T synonymous_variant 1.0 delamanid
pretomanid
ddn 3987020 c.177G>A synonymous_variant 1.0 delamanid
pretomanid
ddn 3987028 p.Asn62Ser missense_variant 1.0 delamanid
pretomanid
ddn 3987035 c.192C>G synonymous_variant 0.93 delamanid
pretomanid
ddn 3987053 c.210T>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3987055 p.Gly71Asp missense_variant 1.0 delamanid
pretomanid
ddn 3987062 c.219C>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987065 c.222T>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3987071 c.228G>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3987089 c.246G>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3987092 p.Glu83Asp missense_variant 1.0 delamanid Uncertain significance
pretomanid
clpC1 4038271 p.Pro812Ala missense_variant 1.0 pyrazinamide
clpC1 4038272 c.2433T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038308 c.2397G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038314 c.2391T>G synonymous_variant 1.0 pyrazinamide
clpC1 4038335 c.2370C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038344 c.2361G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038350 c.2355C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038383 c.2322G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038407 c.2298G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 1.0 pyrazinamide
clpC1 4038508 c.2197C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038519 p.Arg729Gln missense_variant 1.0 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 1.0 pyrazinamide
clpC1 4038533 c.2172C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038536 c.2169C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038587 c.2118C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038800 c.1905C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038838 c.1867C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038839 c.1866G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038902 c.1803C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038980 c.1725C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038995 c.1710G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039009 c.1696C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039090 c.1615C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039337 c.1368A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039352 c.1353C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039391 c.1314T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039484 c.1221T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039493 c.1212C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039514 c.1191C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039541 c.1164C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039552 c.1153C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039553 c.1152C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039574 p.Ala377Ser missense_variant 1.0 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039586 c.1119G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039601 c.1104G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039693 c.1012C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039733 c.972G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039754 c.951G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039763 c.942C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039766 c.939T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039868 c.837C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039942 c.763C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039946 c.759A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039996 p.Glu237Gln missense_variant 1.0 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.92 pyrazinamide
clpC1 4040048 c.657C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040091 c.613_614delTCinsAG synonymous_variant 1.0 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040594 c.111G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.91 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040636 c.69C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
embC 4239044 c.-819G>C upstream_gene_variant 1.0 ethambutol
embC 4239625 c.-238A>G upstream_gene_variant 1.0 ethambutol
embC 4239638 c.-225C>A upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239641 c.-222G>C upstream_gene_variant 1.0 ethambutol
embC 4239661 c.-202A>C upstream_gene_variant 1.0 ethambutol
embC 4239663 c.-200C>G upstream_gene_variant 1.0 ethambutol
embC 4239671 c.-192C>G upstream_gene_variant 1.0 ethambutol
embC 4239674 c.-189C>G upstream_gene_variant 1.0 ethambutol
embC 4240150 c.288A>G synonymous_variant 1.0 ethambutol
embC 4240151 p.Ser97Pro missense_variant 1.0 ethambutol
embC 4240726 c.864G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240741 c.879C>T synonymous_variant 1.0 ethambutol
embC 4240777 c.915G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 1.0 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240795 c.933C>G synonymous_variant 1.0 ethambutol
embC 4240801 c.939C>T synonymous_variant 1.0 ethambutol
embC 4240831 c.969T>C synonymous_variant 1.0 ethambutol
embC 4240858 c.996G>A synonymous_variant 1.0 ethambutol
embC 4240859 p.Leu333Met missense_variant 1.0 ethambutol
embC 4240867 c.1005T>G synonymous_variant 1.0 ethambutol
embC 4240918 c.1056G>C synonymous_variant 1.0 ethambutol
embC 4240921 c.1059C>G synonymous_variant 1.0 ethambutol
embC 4240924 c.1062C>G synonymous_variant 1.0 ethambutol
embC 4240934 c.1072_1074delGTAinsTG frameshift_variant&stop_gained 1.0 ethambutol
embC 4240945 c.1083T>C synonymous_variant 1.0 ethambutol
embC 4241017 c.1155T>C synonymous_variant 0.9 ethambutol
embC 4241039 p.Asp393Asn missense_variant 1.0 ethambutol
embC 4241095 c.1233C>T synonymous_variant 1.0 ethambutol
embC 4241107 c.1245G>C synonymous_variant 1.0 ethambutol
embC 4241140 c.1278A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241153 p.Ile431Leu missense_variant 1.0 ethambutol
embA 4244165 c.933T>G synonymous_variant 1.0 ethambutol
embA 4244170 p.Gln313Arg missense_variant 1.0 ethambutol
embA 4244178 p.Ala316Ser missense_variant 1.0 ethambutol
embA 4244603 c.1371G>A synonymous_variant 1.0 ethambutol
embA 4244612 c.1380C>G synonymous_variant 1.0 ethambutol
embA 4244615 c.1383G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244616 c.1384_1386delGCGinsTA frameshift_variant&stop_gained 1.0 ethambutol Uncertain significance
embA 4244619 c.1387T>C synonymous_variant 1.0 ethambutol
embA 4244645 c.1413T>C synonymous_variant 1.0 ethambutol
embA 4244648 c.1416G>C synonymous_variant 1.0 ethambutol
embA 4244649 p.Asp473Ser missense_variant 1.0 ethambutol
embA 4244663 c.1431C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244669 c.1437G>C synonymous_variant 1.0 ethambutol
embA 4244675 c.1443A>G synonymous_variant 1.0 ethambutol
embA 4244681 c.1449A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244684 c.1452C>G synonymous_variant 1.0 ethambutol
embA 4244702 c.1470C>G synonymous_variant 1.0 ethambutol
embA 4244705 c.1473G>C synonymous_variant 1.0 ethambutol
embA 4244708 c.1476C>G synonymous_variant 1.0 ethambutol
embA 4244714 c.1482C>G synonymous_variant 1.0 ethambutol
embA 4244792 c.1560G>C synonymous_variant 1.0 ethambutol
embA 4244802 p.Leu524Met missense_variant 0.92 ethambutol
embA 4244805 c.1573C>T synonymous_variant 0.86 ethambutol
embA 4244822 c.1590G>A synonymous_variant 1.0 ethambutol
embA 4244823 p.Val531Met missense_variant 1.0 ethambutol
embA 4244856 p.Ala542Pro missense_variant 1.0 ethambutol
embA 4244885 c.1653A>G synonymous_variant 1.0 ethambutol
embA 4244897 c.1665T>G synonymous_variant 1.0 ethambutol
embA 4244903 c.1671G>C synonymous_variant 1.0 ethambutol
embA 4245149 c.1917C>G synonymous_variant 1.0 ethambutol
embA 4245182 c.1950T>C synonymous_variant 1.0 ethambutol
embA 4245186 p.Thr652Ala missense_variant 1.0 ethambutol
embA 4245194 c.1962G>A synonymous_variant 1.0 ethambutol
embA 4245195 c.1963_1965delATCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4245200 c.1968C>G synonymous_variant 1.0 ethambutol
embA 4245206 c.1974A>C synonymous_variant 1.0 ethambutol
embA 4245207 c.1975T>C synonymous_variant 1.0 ethambutol
embA 4245215 c.1983A>C synonymous_variant 1.0 ethambutol
embA 4245224 c.1992T>C synonymous_variant 1.0 ethambutol
embA 4245248 c.2016G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245257 c.2025A>G synonymous_variant 1.0 ethambutol
embA 4245263 c.2031A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245345 p.Met705Leu missense_variant 1.0 ethambutol
embA 4245355 p.Ala708Gly missense_variant 1.0 ethambutol
embA 4245368 c.2136T>C synonymous_variant 1.0 ethambutol
embA 4245375 c.2143_2145delCTTinsAG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4245402 c.2170_2172delACCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4245409 c.2178_2179delCA frameshift_variant 1.0 ethambutol Uncertain significance
embA 4245413 p.Ser727Arg missense_variant 1.0 ethambutol
embA 4245414 c.2182_2183insAT frameshift_variant 1.0 ethambutol Uncertain significance
embA 4245424 c.2192_2193insGCCCAG disruptive_inframe_insertion 1.0 ethambutol
embA 4245431 c.2199T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245434 c.2202G>C synonymous_variant 1.0 ethambutol
embA 4245458 c.2226G>A synonymous_variant 1.0 ethambutol
embA 4245464 c.2232C>T synonymous_variant 1.0 ethambutol
embA 4245473 c.2241C>T synonymous_variant 1.0 ethambutol
embA 4245488 c.2256G>C synonymous_variant 1.0 ethambutol
embA 4245497 c.2265C>T synonymous_variant 1.0 ethambutol
embA 4245501 c.2269_2271delGCGinsAC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4245510 c.2278_2280delCCGinsTC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4245524 c.2292G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245620 c.-894T>C upstream_gene_variant 1.0 ethambutol
embB 4245623 c.-891G>A upstream_gene_variant 1.0 ethambutol
embB 4245662 c.-852G>C upstream_gene_variant 1.0 ethambutol
embA 4245674 c.2442A>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245677 c.-837G>C upstream_gene_variant 1.0 ethambutol
embB 4245683 c.-831C>T upstream_gene_variant 1.0 ethambutol
embA 4245693 p.Ile821Val missense_variant 1.0 ethambutol
embB 4245714 c.-800C>T upstream_gene_variant 1.0 ethambutol
embB 4245725 c.-789A>G upstream_gene_variant 1.0 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 1.0 ethambutol
embB 4245734 c.-780G>C upstream_gene_variant 1.0 ethambutol
embB 4245737 c.-777A>T upstream_gene_variant 1.0 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 1.0 ethambutol
embA 4245772 p.Asn847Thr missense_variant 1.0 ethambutol
embB 4245803 c.-711C>T upstream_gene_variant 1.0 ethambutol
embB 4245806 c.-708G>A upstream_gene_variant 1.0 ethambutol
embA 4245807 c.2575_2577delTTAinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embB 4245812 c.-702G>T upstream_gene_variant 1.0 ethambutol
embA 4245813 p.Pro861Ala missense_variant 1.0 ethambutol
embA 4245822 p.Pro864Ala missense_variant 1.0 ethambutol
embB 4245839 c.-675G>C upstream_gene_variant 1.0 ethambutol
embB 4245857 c.-657C>G upstream_gene_variant 1.0 ethambutol
embA 4245869 c.2637C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245875 c.-639G>A upstream_gene_variant 1.0 ethambutol
embB 4245887 c.-627T>C upstream_gene_variant 1.0 ethambutol
embA 4245891 p.Ile887Val missense_variant 1.0 ethambutol
embB 4245905 c.-609C>T upstream_gene_variant 1.0 ethambutol
embB 4245906 c.-608C>T upstream_gene_variant 1.0 ethambutol
embB 4245923 c.-591C>A upstream_gene_variant 1.0 ethambutol
embA 4245930 c.2698_2700delGGCinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4245935 c.2703G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245942 p.Arg904Gly missense_variant 1.0 ethambutol
embB 4245953 c.-561A>G upstream_gene_variant 1.0 ethambutol
embB 4245956 c.-558G>C upstream_gene_variant 1.0 ethambutol
embA 4245965 c.2733A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245968 c.-546T>C upstream_gene_variant 1.0 ethambutol
embA 4245978 p.Ile916Leu missense_variant 1.0 ethambutol
embB 4245983 c.-531A>G upstream_gene_variant 1.0 ethambutol
embB 4245992 c.-522C>G upstream_gene_variant 1.0 ethambutol
embB 4246004 c.-510T>C upstream_gene_variant 1.0 ethambutol
embB 4246005 c.-509C>T upstream_gene_variant 1.0 ethambutol
embB 4246013 c.-501T>C upstream_gene_variant 1.0 ethambutol
embA 4246020 p.Ala930Thr missense_variant 1.0 ethambutol
embA 4246028 c.2796G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246070 c.-444G>C upstream_gene_variant 1.0 ethambutol
embB 4246082 c.-432T>C upstream_gene_variant 1.0 ethambutol
embB 4246109 c.-405C>G upstream_gene_variant 1.0 ethambutol
embB 4246115 c.-399T>C upstream_gene_variant 1.0 ethambutol
embA 4246128 c.2896_2898delTCTinsAG frameshift_variant&synonymous_variant 1.0 ethambutol Uncertain significance
embA 4246138 p.Arg969Gln missense_variant 1.0 ethambutol
embB 4246140 c.-374T>C upstream_gene_variant 1.0 ethambutol
embB 4246148 c.-366G>C upstream_gene_variant 1.0 ethambutol
embB 4246151 c.-363A>C upstream_gene_variant 1.0 ethambutol
embA 4246152 p.Ala974Arg missense_variant 1.0 ethambutol
embB 4246172 c.-342C>T upstream_gene_variant 1.0 ethambutol
embB 4246184 c.-330A>C upstream_gene_variant 1.0 ethambutol
embB 4246205 c.-309A>G upstream_gene_variant 1.0 ethambutol
embB 4246211 c.-303T>C upstream_gene_variant 1.0 ethambutol
embB 4246217 c.-297G>A upstream_gene_variant 1.0 ethambutol
embA 4246220 c.2988T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246223 c.-291C>T upstream_gene_variant 1.0 ethambutol
embA 4246227 c.2995_2997delATTinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4246235 c.3003G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246244 c.-270G>A upstream_gene_variant 1.0 ethambutol
embA 4246254 p.Leu1008Met missense_variant 1.0 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 1.0 ethambutol
embB 4246307 c.-207G>C upstream_gene_variant 1.0 ethambutol
embB 4246316 c.-198T>C upstream_gene_variant 1.0 ethambutol
embB 4246346 c.-168C>G upstream_gene_variant 1.0 ethambutol
embA 4246359 c.3127_3129delGCCinsTG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embB 4246373 c.-141T>C upstream_gene_variant 1.0 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 1.0 ethambutol
embA 4246398 p.Ser1056Thr missense_variant 1.0 ethambutol
embA 4246413 p.His1061Tyr missense_variant 1.0 ethambutol
embB 4247440 c.927C>G synonymous_variant 1.0 ethambutol
embB 4247470 c.957T>C synonymous_variant 1.0 ethambutol
embB 4247497 c.984T>C synonymous_variant 1.0 ethambutol
embB 4247500 c.987C>G synonymous_variant 1.0 ethambutol
embB 4247512 c.999T>C synonymous_variant 1.0 ethambutol
embB 4247566 c.1053C>G synonymous_variant 1.0 ethambutol
embB 4247579 p.Ala356Phe missense_variant 1.0 ethambutol
embB 4247608 c.1095G>C synonymous_variant 1.0 ethambutol
embB 4247611 c.1098G>C synonymous_variant 1.0 ethambutol
embB 4247632 c.1119C>G synonymous_variant 1.0 ethambutol
embB 4247645 p.Glu378Thr missense_variant 1.0 ethambutol
embB 4247648 p.Ala379Ser missense_variant 1.0 ethambutol
embB 4247657 p.Pro382Ala missense_variant 1.0 ethambutol
embB 4247671 c.1158G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247679 p.Met389Thr missense_variant 1.0 ethambutol
embB 4247684 c.1171T>C synonymous_variant 1.0 ethambutol
embB 4247722 c.1209G>C synonymous_variant 1.0 ethambutol
embB 4247725 c.1212G>C synonymous_variant 1.0 ethambutol
embB 4247728 c.1215G>A synonymous_variant 1.0 ethambutol
embB 4247743 c.1230C>G synonymous_variant 1.0 ethambutol
embB 4247761 c.1248T>C synonymous_variant 1.0 ethambutol
embB 4247779 c.1266C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247785 c.1272G>C synonymous_variant 1.0 ethambutol
embB 4247800 c.1287A>C synonymous_variant 1.0 ethambutol
embB 4247830 c.1317A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247858 c.1345C>T synonymous_variant 1.0 ethambutol
embB 4247899 p.Met462Ile missense_variant 1.0 ethambutol
embB 4247911 p.Leu466Phe missense_variant 1.0 ethambutol
embB 4247915 p.Arg468Lys missense_variant 1.0 ethambutol
embB 4247920 c.1407T>C synonymous_variant 1.0 ethambutol
embB 4247923 c.1410T>C synonymous_variant 1.0 ethambutol
embB 4247932 c.1419C>G synonymous_variant 1.0 ethambutol
embB 4247948 p.Val479Leu missense_variant 1.0 ethambutol Uncertain significance
embB 4247975 p.Val488Ile missense_variant 1.0 ethambutol Uncertain significance
embB 4247989 c.1476G>C synonymous_variant 1.0 ethambutol
embB 4248001 c.1488C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248007 c.1494C>G synonymous_variant 1.0 ethambutol
embB 4248130 c.1617G>C synonymous_variant 1.0 ethambutol
embB 4248142 c.1629T>C synonymous_variant 1.0 ethambutol
embB 4248143 c.1630T>C synonymous_variant 1.0 ethambutol
embB 4248169 c.1656C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248175 c.1662G>A synonymous_variant 1.0 ethambutol
embB 4248178 c.1665C>T synonymous_variant 1.0 ethambutol
embB 4248206 p.Ser565Gly missense_variant 1.0 ethambutol Uncertain significance
embB 4248214 c.1701C>G synonymous_variant 1.0 ethambutol
embB 4248217 c.1704C>G synonymous_variant 1.0 ethambutol
embB 4248220 c.1707A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248233 c.1720C>T synonymous_variant 1.0 ethambutol
embB 4248252 p.Gly580Ala missense_variant 1.0 ethambutol
embB 4248266 c.1753C>T synonymous_variant 1.0 ethambutol
embB 4248277 c.1764G>C synonymous_variant 1.0 ethambutol
embB 4248280 c.1767C>G synonymous_variant 1.0 ethambutol
embB 4248316 c.1803C>G synonymous_variant 1.0 ethambutol
embB 4248319 c.1806A>G synonymous_variant 1.0 ethambutol
embB 4248334 c.1821C>G synonymous_variant 1.0 ethambutol
embB 4248349 c.1836G>A synonymous_variant 1.0 ethambutol
embB 4248358 c.1845C>G synonymous_variant 1.0 ethambutol
embB 4248361 c.1848A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248379 c.1866G>A synonymous_variant 1.0 ethambutol
embB 4248407 c.1894_1896delTTAinsGG frameshift_variant&missense_variant 1.0 ethambutol
embB 4248412 p.Phe633Leu missense_variant 1.0 ethambutol
embB 4248416 p.Leu635Met missense_variant 1.0 ethambutol
embB 4248424 c.1911G>A synonymous_variant 1.0 ethambutol
embB 4248430 c.1917T>C synonymous_variant 1.0 ethambutol
embB 4248448 c.1935C>T synonymous_variant 1.0 ethambutol
embB 4248457 c.1944T>C synonymous_variant 1.0 ethambutol
embB 4248472 c.1959T>C synonymous_variant 1.0 ethambutol
embB 4248496 c.1983G>C synonymous_variant 1.0 ethambutol
embB 4248504 p.Asp664Ala missense_variant 1.0 ethambutol
embB 4248508 c.1995G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4267529 c.1308T>C synonymous_variant 1.0 ethambutol
aftB 4267535 c.1302A>G synonymous_variant 1.0 ethambutol
aftB 4267556 c.1281G>C synonymous_variant 1.0 ethambutol
aftB 4267574 c.1263G>C synonymous_variant 1.0 ethambutol
aftB 4267580 c.1257G>A synonymous_variant 1.0 ethambutol
aftB 4267592 c.1245C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4267622 c.1213_1215delTCGinsAC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
aftB 4267634 p.Arg401His missense_variant 1.0 ethambutol
aftB 4267637 c.1200C>G synonymous_variant 1.0 ethambutol
aftB 4267649 c.1188T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4267667 c.1170A>G synonymous_variant 1.0 ethambutol
aftB 4269660 c.-824C>A upstream_gene_variant 1.0 ethambutol
ubiA 4269663 c.169_171delATGinsGC frameshift_variant&missense_variant 1.0 ethambutol
aftB 4269669 c.-833G>T upstream_gene_variant 1.0 ethambutol
ubiA 4269676 p.Ser53Thr missense_variant 1.0 ethambutol
aftB 4269678 c.-842C>G upstream_gene_variant 1.0 ethambutol
ubiA 4269688 p.Val49Ala missense_variant 1.0 ethambutol Uncertain significance
ubiA 4269690 c.144C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim