TB-Profiler result

Run: SRR12708372
Summary

Run ID: SRR12708372

Sample name:

Date: 2024-10-05T06:18:03.509772

Number of reads: 130611

Percentage reads mapped: 12.22

Median coverage: 2.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.88
lineage4.9 Euro-American (H37Rv-like) None 0.89
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 660 c.660G>C synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>C synonymous_variant 0.88 isoniazid
dnaA 666 c.666C>G synonymous_variant 0.88 isoniazid
dnaA 675 c.675C>G synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 681 c.681G>T synonymous_variant 0.88 isoniazid
dnaA 682 c.682_684delTTGinsCTC synonymous_variant 0.88 isoniazid
dnaA 687 c.687C>T synonymous_variant 0.88 isoniazid
dnaA 693 c.693A>C synonymous_variant 0.88 isoniazid
dnaA 705 c.705A>G synonymous_variant 0.88 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.88 isoniazid
dnaA 714 c.714C>T synonymous_variant 0.89 isoniazid
dnaA 720 c.720G>A synonymous_variant 0.9 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 747 c.747G>T synonymous_variant 0.92 isoniazid
dnaA 748 c.748_750delCTCinsTTG synonymous_variant 0.92 isoniazid
dnaA 763 p.Lys255Arg missense_variant 1.0 isoniazid
dnaA 793 p.Val265Ile missense_variant 1.0 isoniazid Uncertain significance
dnaA 801 c.801G>T synonymous_variant 1.0 isoniazid
dnaA 804 c.804G>C synonymous_variant 1.0 isoniazid
dnaA 805 c.805_807delTTGinsCTC synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.86 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.85 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 0.88 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.88 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.88 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.87 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.87 isoniazid Not assoc w R - Interim
dnaA 885 c.885T>C synonymous_variant 0.83 isoniazid
dnaA 888 c.888C>G synonymous_variant 0.82 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.81 isoniazid
dnaA 903 c.903C>G synonymous_variant 0.81 isoniazid Not assoc w R - Interim
dnaA 909 c.909A>C synonymous_variant 0.79 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 0.79 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.79 isoniazid
dnaA 924 c.924C>G synonymous_variant 0.79 isoniazid
dnaA 928 p.Gln310Gly missense_variant 0.79 isoniazid
dnaA 933 c.933C>G synonymous_variant 0.79 isoniazid
dnaA 952 c.952C>T synonymous_variant 0.9 isoniazid
gyrA 6655 c.-647T>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 6739 c.-563C>T upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6754 c.-548C>T upstream_gene_variant 0.63 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6772 c.1533C>G synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 0.67 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrA 7526 c.225G>A synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7547 c.246C>T synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7553 c.252C>T synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7559 c.258G>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7574 c.273G>C synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7589 c.288G>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>T synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>T synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7637 c.336C>A synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8870 c.1569G>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>G synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8942 c.1641G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8946 c.1645T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8957 c.1656C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9330 p.Asn677His missense_variant 0.7 levofloxacin
moxifloxacin
gyrA 9345 c.2044_2046delAGGinsCGA synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9351 c.2050_2052delTCGinsAGT synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
fgd1 491112 c.330G>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 491115 c.333G>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 491121 c.339A>G synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 491137 p.Glu119Ile missense_variant 0.91 pretomanid
delamanid
clofazimine
fgd1 491144 p.Ala121Glu missense_variant 0.91 pretomanid
delamanid
clofazimine
fgd1 491166 c.384G>T synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fgd1 491172 c.390C>G synonymous_variant 0.9 pretomanid
delamanid
clofazimine
nusG 734452 p.Glu67Gln missense_variant 0.9 rifampicin Uncertain significance
nusG 734460 c.207G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734497 p.Val82Ile missense_variant 0.95 rifampicin Uncertain significance
nusG 734532 c.279A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
nusG 734535 c.282C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
nusG 734807 p.Tyr185Phe missense_variant 0.8 rifampicin
nusG 734820 c.567A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>C synonymous_variant 0.75 rifampicin
nusG 734834 p.Met194Thr missense_variant 0.82 rifampicin Uncertain significance
nusG 734841 c.588G>T synonymous_variant 0.82 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.82 rifampicin
nusG 734850 c.597C>G synonymous_variant 0.82 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.82 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.82 rifampicin
nusG 734859 c.606G>C synonymous_variant 0.82 rifampicin
nusG 734864 p.Thr204Ser missense_variant 0.82 rifampicin
nusG 734889 c.636G>A synonymous_variant 0.75 rifampicin
nusG 734893 p.Lys214Arg missense_variant 0.73 rifampicin
nusG 734910 c.657C>G synonymous_variant 0.7 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760274 p.Glu156Asp missense_variant 0.79 rifampicin Uncertain significance
rpoB 760276 p.Lys157Met missense_variant 0.79 rifampicin Uncertain significance
rpoB 760283 c.477G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760415 c.609C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760418 c.612G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760460 c.654G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.82 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760541 c.735G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 0.81 rifampicin
rpoB 760567 p.Ser254Trp missense_variant 0.76 rifampicin
rpoB 760568 c.762_763insGC frameshift_variant 0.76 rifampicin
rpoB 760571 c.765G>C synonymous_variant 0.76 rifampicin
rpoB 760588 p.Thr261Ile missense_variant 0.81 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.81 rifampicin
rpoB 760595 c.789C>T synonymous_variant 0.81 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 0.82 rifampicin
rpoB 760608 c.802C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760611 c.805T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760668 p.Thr288Ala missense_variant 0.82 rifampicin Uncertain significance
rpoB 760674 c.868T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760805 c.999G>C synonymous_variant 0.9 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.83 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.83 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760858 p.Val351Ala missense_variant 0.88 rifampicin Uncertain significance
rpoB 760862 c.1056G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760865 c.1059C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760886 p.Glu360Asp missense_variant 0.88 rifampicin Uncertain significance
rpoB 760887 p.Thr361Val missense_variant 0.88 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760928 c.1122G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760943 c.1137C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761171 c.1365C>T synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761178 p.Ser458Thr missense_variant 0.77 rifampicin Uncertain significance
rpoB 761186 p.Glu460Asp missense_variant 0.79 rifampicin Uncertain significance
rpoB 761189 c.1383T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761219 c.1413G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761234 c.1428G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761564 c.1758G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761612 c.1806G>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761657 c.1851C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761666 c.1860G>C synonymous_variant 0.91 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.91 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.9 rifampicin
rpoB 761681 c.1875G>A synonymous_variant 0.73 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 0.73 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 0.8 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.8 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 0.8 rifampicin
rpoB 761705 c.1899C>A synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761948 c.2142G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>A synonymous_variant 0.8 rifampicin
rpoB 761955 p.Ile717Val missense_variant 0.8 rifampicin Uncertain significance
rpoB 761969 c.2163G>A synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761990 c.2184G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 762056 c.2250G>A synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762194 c.2388G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762275 c.2469C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762866 c.3060C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 0.82 rifampicin Uncertain significance
rpoB 762894 c.3088C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762899 c.3093G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762917 c.3111C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 763082 c.3276C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 763088 c.3282C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763145 c.3339G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 763531 c.162G>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763657 c.288G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.82 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.8 rifampicin
rpoC 763711 c.342G>C synonymous_variant 0.84 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.84 rifampicin
rpoC 763732 c.363C>A synonymous_variant 0.84 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.82 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.8 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.79 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.82 rifampicin
rpoC 763960 c.591T>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763969 c.600C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 763987 c.618C>T synonymous_variant 0.73 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.73 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.73 rifampicin
rpoC 763999 c.630C>T synonymous_variant 0.73 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.73 rifampicin
rpoC 764003 p.Ala212Ser missense_variant 0.73 rifampicin
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 0.92 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 0.92 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.92 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.93 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764054 c.685C>T synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.95 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.95 rifampicin
rpoC 764084 p.Asn239Val missense_variant 0.95 rifampicin
rpoC 764095 c.726C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764098 c.729A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764143 c.774G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764147 p.Ser260Ala missense_variant 0.78 rifampicin Uncertain significance
rpoC 764150 p.Ile261Val missense_variant 0.78 rifampicin Uncertain significance
rpoC 764165 p.Glu266Gln missense_variant 0.72 rifampicin
rpoC 764353 c.984G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764428 c.1059G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.92 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764534 c.1165C>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764542 c.1173C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764545 c.1176C>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764560 c.1191T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764692 c.1323C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.9 rifampicin Not assoc w R
rpoC 764810 p.Pro481Ala missense_variant 0.9 rifampicin Uncertain significance
rpoC 764815 c.1446A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.94 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.94 rifampicin Uncertain significance
rpoC 764932 c.1563C>A synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579_1581delTTGinsCTC synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 765841 c.2472G>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765861 p.Phe831Tyr missense_variant 0.93 rifampicin Uncertain significance
rpoC 765875 p.Val836Ile missense_variant 0.93 rifampicin Uncertain significance
rpoC 765907 c.2538G>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765910 c.2541G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765962 c.2593_2595delTTGinsCTT synonymous_variant 0.69 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 765973 c.2604C>G synonymous_variant 0.64 rifampicin
rpoC 765979 c.2610C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767044 c.3675G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 767080 c.3711G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767107 c.3738C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767125 c.3756G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767149 c.3780C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 767179 c.3810C>T synonymous_variant 0.8 rifampicin
rpoC 767180 p.Ala1271Ser missense_variant 0.79 rifampicin Uncertain significance
rpoC 767191 c.3822C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 767203 c.3834C>G synonymous_variant 0.76 rifampicin
rpoC 767206 c.3837C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.71 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 767254 c.3885G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpsL 781572 p.Gln5Asn missense_variant 0.9 streptomycin
rpsL 781586 c.27C>T synonymous_variant 0.93 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.94 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.95 streptomycin
rpsL 781616 c.57C>G synonymous_variant 0.95 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.95 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 0.95 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781658 c.99A>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781670 c.111G>C synonymous_variant 1.0 streptomycin
rpsL 781802 c.243G>C synonymous_variant 0.92 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.93 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.94 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.94 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.9 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 0.9 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.9 streptomycin
rpsL 781877 c.318T>A synonymous_variant 0.91 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.91 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.91 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.9 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.94 streptomycin
sigE 1364640 c.228G>A synonymous_variant 0.64 pyrazinamide
sigE 1364644 p.Lys78Gln missense_variant 0.67 pyrazinamide
sigE 1364650 p.Thr80Ala missense_variant 0.67 pyrazinamide Uncertain significance
sigE 1364670 c.258G>A synonymous_variant 0.67 pyrazinamide
sigE 1364676 c.264C>T synonymous_variant 0.67 pyrazinamide
sigE 1364680 p.Gln90Glu missense_variant 0.67 pyrazinamide
sigE 1364685 c.273C>T synonymous_variant 0.67 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 0.67 pyrazinamide
sigE 1364694 c.282G>C synonymous_variant 0.67 pyrazinamide
sigE 1364703 c.291G>C synonymous_variant 0.67 pyrazinamide
sigE 1364709 c.297T>G synonymous_variant 0.71 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 0.71 pyrazinamide
sigE 1364718 c.306C>T synonymous_variant 0.71 pyrazinamide
sigE 1364726 p.Asn105Ser missense_variant 0.71 pyrazinamide
sigE 1364733 p.His107Gln missense_variant 0.73 pyrazinamide
sigE 1364742 c.330A>G synonymous_variant 0.69 pyrazinamide
sigE 1364751 c.339C>A synonymous_variant 0.64 pyrazinamide
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.93 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.93 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.93 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472846 n.1001C>T non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472847 n.1002G>A non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472848 n.1003T>C non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>T non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472861 n.1016G>A non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.94 kanamycin Not assoc w R
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473082 n.1237G>A non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473129 n.1284C>T non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrl 1473717 n.60G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>C non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473812 n.155G>A non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid
rrl 1473814 n.157A>T non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1473839 n.182G>A non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473888 n.231T>C non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1473950 n.293G>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1474074 n.417C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474089 n.432C>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1474100 n.443C>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1474103 n.446A>C non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524_525insT non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1474184 n.527C>A non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1474185 n.529delA non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1474291 n.634_649delTTTCCTCTCCGGAGGAinsC non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474415 n.759_781delCACACGCGCATACGCGCGTGTGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1474709 n.1052_1057delGTGGTGinsAATAAGT non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474717 n.1060A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474743 n.1086T>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475061 n.1406delA non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475202 n.1545G>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1475220 n.1563G>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475443 n.1786G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475475 n.1818C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475760 n.2105_2106delGC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475765 n.2108A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.95 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.91 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.88 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476665 n.3008T>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
inhA 1674912 c.711G>C synonymous_variant 0.7 isoniazid
ethionamide
inhA 1674915 c.714C>G synonymous_variant 0.7 isoniazid
ethionamide
inhA 1674942 c.741T>C synonymous_variant 0.64 isoniazid
ethionamide
inhA 1674949 c.748C>T synonymous_variant 0.7 isoniazid
ethionamide
inhA 1674954 c.753G>C synonymous_variant 0.7 isoniazid
ethionamide
inhA 1674957 c.756G>C synonymous_variant 0.7 isoniazid
ethionamide
inhA 1674963 c.762G>C synonymous_variant 0.7 isoniazid
ethionamide
rpsA 1833589 c.48A>C synonymous_variant 0.79 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.79 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.79 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 0.82 pyrazinamide
rpsA 1833616 c.75A>T synonymous_variant 0.82 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.83 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 0.84 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 0.85 pyrazinamide
rpsA 1833697 c.156C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833700 c.159C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833733 c.192C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 1.0 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833823 c.282G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.95 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.96 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.96 pyrazinamide
rpsA 1833874 c.333T>G synonymous_variant 0.97 pyrazinamide
rpsA 1833886 c.345C>G synonymous_variant 0.94 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.91 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.9 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.88 pyrazinamide
rpsA 1833961 c.420C>G synonymous_variant 0.88 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.91 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.9 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.9 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.92 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834033 c.492C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834073 p.Lys178Arg missense_variant 0.86 pyrazinamide
rpsA 1834228 c.687C>A synonymous_variant 0.79 pyrazinamide
rpsA 1834231 c.690T>G synonymous_variant 0.79 pyrazinamide
rpsA 1834234 c.693G>T synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
rpsA 1834240 c.699T>C synonymous_variant 0.69 pyrazinamide
rpsA 1834246 c.705G>T synonymous_variant 0.72 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.68 pyrazinamide
rpsA 1834252 c.711C>G synonymous_variant 0.7 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.75 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
rpsA 1834294 c.753G>T synonymous_variant 0.8 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 0.78 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.77 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.78 pyrazinamide
rpsA 1834327 c.786G>T synonymous_variant 0.76 pyrazinamide
rpsA 1834357 c.816T>C synonymous_variant 0.79 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834411 c.870T>G synonymous_variant 0.79 pyrazinamide
rpsA 1834414 c.873C>T synonymous_variant 0.85 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.85 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.87 pyrazinamide
rpsA 1834429 c.888C>T synonymous_variant 0.87 pyrazinamide
rpsA 1834438 c.897C>T synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
rpsA 1834451 c.910T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.88 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.87 pyrazinamide
rpsA 1834477 c.936C>T synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
rpsA 1834489 c.948T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834519 c.978G>C synonymous_variant 0.73 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.73 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.73 pyrazinamide
rpsA 1834534 c.993C>T synonymous_variant 0.73 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.64 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.58 pyrazinamide
rpsA 1834552 c.1011G>T synonymous_variant 0.58 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 0.58 pyrazinamide
rpsA 1834557 p.Ala339Gly missense_variant 0.58 pyrazinamide
rpsA 1834645 c.1104C>T synonymous_variant 0.73 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.69 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.69 pyrazinamide
kasA 2517917 c.-198G>C upstream_gene_variant 0.96 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.95 isoniazid
kasA 2517953 c.-162C>T upstream_gene_variant 0.93 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 1.0 isoniazid
Rv2477c 2783317 c.726G>C synonymous_variant 0.82 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783344 c.699C>T synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783347 c.696C>T synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783356 c.687C>G synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783491 c.552C>T synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.8 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783509 c.534C>A synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783515 c.528C>G synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783523 c.520C>T synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 0.8 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
mtrB 3625705 c.909C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625708 c.906C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625711 c.903C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625732 c.882C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625735 c.879C>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625744 c.870G>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625750 c.864G>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 0.93 rifampicin Uncertain significance
bedaquiline
mtrB 3625761 p.Gln285Glu missense_variant 0.92 rifampicin Uncertain significance
bedaquiline
mtrB 3625762 c.852A>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625765 c.849C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625774 c.840G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625783 c.-873C>T upstream_gene_variant 0.93 rifampicin
bedaquiline
mtrB 3625806 c.808A>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625807 c.807C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626704 c.-91C>T upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrB 3626711 c.-98T>C upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3626717 c.-104C>T upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3626726 c.-113T>C upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrB 3626732 c.-119A>G upstream_gene_variant 0.71 rifampicin
bedaquiline
mtrA 3626741 c.609C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626756 c.594C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626759 c.591T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626762 c.588G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626786 c.564A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626792 c.558G>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626825 c.525T>A synonymous_variant 0.84 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626846 c.504G>A synonymous_variant 0.9 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626852 c.-239G>A upstream_gene_variant 0.89 rifampicin
bedaquiline
mtrB 3626857 c.-244T>C upstream_gene_variant 0.88 rifampicin
bedaquiline
mtrB 3626858 c.-245A>G upstream_gene_variant 0.88 rifampicin
bedaquiline
mtrB 3626861 c.-248C>G upstream_gene_variant 0.88 rifampicin
bedaquiline
mtrB 3626866 c.-253T>C upstream_gene_variant 0.88 rifampicin
bedaquiline
mtrB 3626876 c.-263A>G upstream_gene_variant 0.82 rifampicin
bedaquiline
mtrB 3626885 c.-272A>C upstream_gene_variant 0.81 rifampicin
bedaquiline
mtrB 3626890 c.-277T>C upstream_gene_variant 0.81 rifampicin
bedaquiline
mtrB 3626903 c.-290T>C upstream_gene_variant 0.75 rifampicin
bedaquiline
mtrA 3626906 p.Asn148Glu missense_variant 0.8 rifampicin
bedaquiline
mtrB 3626912 c.-299T>G upstream_gene_variant 0.8 rifampicin
bedaquiline
mtrB 3626915 c.-302C>G upstream_gene_variant 0.8 rifampicin
bedaquiline
rpoA 3877554 c.954G>A synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3877560 c.948C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877569 p.Pro313Thr missense_variant 0.86 rifampicin Uncertain significance
rpoA 3877587 c.921A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877593 c.915C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877614 c.894G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877620 c.888G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877665 c.843C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877677 c.831G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.87 rifampicin
rpoA 3877731 c.777G>C synonymous_variant 0.87 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 0.87 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.87 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3877752 p.Asp252Glu missense_variant 0.81 rifampicin
rpoA 3877755 c.753C>T synonymous_variant 0.81 rifampicin
rpoA 3877758 c.750G>C synonymous_variant 0.81 rifampicin
rpoA 3877764 c.744C>A synonymous_variant 0.81 rifampicin
rpoA 3877770 c.738A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877773 c.735G>C synonymous_variant 0.76 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoA 3877797 c.711G>A synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877815 c.693C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877818 c.690A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3877824 c.684G>A synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3877836 c.672A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>A synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3877896 c.612G>A synonymous_variant 0.86 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877929 p.Ile193Val missense_variant 0.81 rifampicin Uncertain significance
rpoA 3877962 c.546G>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 0.88 rifampicin Uncertain significance
rpoA 3877974 c.534G>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3877977 p.Lys177Asn missense_variant 0.86 rifampicin Uncertain significance
rpoA 3877986 c.522G>T synonymous_variant 0.87 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3878160 c.348C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3878196 p.Glu104Ala missense_variant 0.71 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoA 3878259 c.249G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3878271 c.237T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.82 rifampicin Uncertain significance
rpoA 3878301 c.207C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3879073 c.-566A>G upstream_gene_variant 0.8 rifampicin
rpoA 3879079 c.-572A>C upstream_gene_variant 0.8 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.8 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.8 rifampicin
rpoA 3879097 c.-590C>T upstream_gene_variant 0.8 rifampicin
clpC1 4038755 c.1950G>C synonymous_variant 0.9 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 0.9 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.9 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.91 pyrazinamide
clpC1 4038782 c.1923G>T synonymous_variant 0.91 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4038795 p.Ser637Thr missense_variant 0.92 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038815 c.1890G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.92 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039046 c.1659C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039070 c.1635G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039091 c.1614G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.95 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039190 c.1515C>T synonymous_variant 0.95 pyrazinamide
clpC1 4039196 c.1509G>A synonymous_variant 0.95 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 0.95 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.96 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039262 c.1443C>T synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4039265 c.1440C>T synonymous_variant 0.92 pyrazinamide
clpC1 4039271 c.1434G>A synonymous_variant 0.92 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.71 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.69 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.69 pyrazinamide Uncertain significance
clpC1 4039418 c.1287C>G synonymous_variant 0.69 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 0.76 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.82 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.8 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.8 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.8 pyrazinamide
clpC1 4039478 c.1227G>C synonymous_variant 0.84 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.85 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039522 c.1183C>T synonymous_variant 0.95 pyrazinamide
clpC1 4039528 c.1177C>A synonymous_variant 0.95 pyrazinamide
clpC1 4039541 c.1164C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039544 c.1161C>T synonymous_variant 0.96 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039565 c.1140G>T synonymous_variant 0.95 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.95 pyrazinamide Uncertain significance
clpC1 4039571 c.1134G>A synonymous_variant 0.95 pyrazinamide
clpC1 4039574 p.Ala377Gly missense_variant 0.95 pyrazinamide
clpC1 4039586 c.1119G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039601 c.1104G>A synonymous_variant 0.96 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039619 c.1086G>A synonymous_variant 0.95 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.95 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.91 pyrazinamide
clpC1 4039685 c.1020C>G synonymous_variant 0.91 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.85 pyrazinamide
clpC1 4039733 c.972G>A synonymous_variant 0.82 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.81 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.8 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.79 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.79 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.8 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.8 pyrazinamide
clpC1 4039763 c.942C>T synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
clpC1 4039769 c.936C>G synonymous_variant 0.82 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.8 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.81 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.8 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 0.8 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.82 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.83 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039868 c.837C>T synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4039913 c.792C>T synonymous_variant 0.95 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039943 c.762G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039946 c.759A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039957 c.748C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039964 c.741C>G synonymous_variant 0.96 pyrazinamide
clpC1 4039975 p.Asp244Asn missense_variant 0.96 pyrazinamide Uncertain significance
clpC1 4039979 c.726C>G synonymous_variant 0.96 pyrazinamide
clpC1 4039982 c.723G>A synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040009 c.696C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040021 c.684A>T synonymous_variant 0.92 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 0.91 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.91 pyrazinamide
clpC1 4040459 c.246C>G synonymous_variant 0.7 pyrazinamide
clpC1 4040462 c.243C>T synonymous_variant 0.7 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.7 pyrazinamide
clpC1 4040480 c.225T>C synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
clpC1 4040495 c.210C>T synonymous_variant 0.75 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.84 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>G synonymous_variant 0.83 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.82 pyrazinamide
clpC1 4040558 c.147G>C synonymous_variant 0.88 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.88 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4040579 c.126A>G synonymous_variant 0.78 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.88 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.87 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCTG synonymous_variant 0.87 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.87 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.87 pyrazinamide
panD 4044150 c.132A>C synonymous_variant 0.6 pyrazinamide
panD 4044156 c.126A>G synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
panD 4044167 c.115C>T synonymous_variant 0.6 pyrazinamide
panD 4044171 c.111C>T synonymous_variant 0.6 pyrazinamide
panD 4044174 c.108C>T synonymous_variant 0.6 pyrazinamide
glpK 4138601 c.1155G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138606 c.1150T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138607 c.1149G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138610 c.1146C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138616 c.1140G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138625 c.1131G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138631 c.1125C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138634 c.1122G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim