TB-Profiler result

Run: ERR4769433
Summary

Run ID: ERR4769433

Sample name:

Date: 2024-10-05T03:12:15.961073

Number of reads: 74708

Percentage reads mapped: 3.5

Median coverage: 0.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: RR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 0.99
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB p.Pro439Ser Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid
ethambutol
pyrazinamide
streptomycin rrs n.799C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpoB 761121 p.Pro439Ser missense_variant 1.0 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
rpoB 761132 c.1326G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 1.0 rifampicin
rpoB 761156 c.1350G>C synonymous_variant 1.0 rifampicin
rpoB 761159 c.1353G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761162 c.1356G>C synonymous_variant 1.0 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 1.0 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761196 p.Leu464Ile missense_variant 1.0 rifampicin
rpoB 761222 c.1416G>C synonymous_variant 1.0 rifampicin
rpoB 761231 c.1425C>A synonymous_variant 1.0 rifampicin
rpoB 761987 c.2181C>T synonymous_variant 1.0 rifampicin
rpoB 761998 c.2193_2195delGTC disruptive_inframe_deletion 1.0 rifampicin
rpoB 762005 c.2200_2201insAGC disruptive_inframe_insertion 1.0 rifampicin
rpoB 762009 p.Leu735Val missense_variant 1.0 rifampicin
rpoB 762014 c.2208C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762024 p.Val740Ile missense_variant 1.0 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762080 c.2274G>C synonymous_variant 1.0 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762104 p.Asp766Glu missense_variant 1.0 rifampicin
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762122 p.Asp772Glu missense_variant 1.0 rifampicin
rpoB 762125 p.Glu773Asp missense_variant 1.0 rifampicin
rpoB 762128 c.2322G>C synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762132 p.Ala776Arg missense_variant 1.0 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762173 p.Glu789Asp missense_variant 1.0 rifampicin
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762181 p.Asp792Ala missense_variant 1.0 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762194 c.2388G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 1.0 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762248 c.2442G>C synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762842 c.-528G>C upstream_gene_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762858 p.Thr1018Ser missense_variant 1.0 rifampicin
rpoC 762863 c.-507T>G upstream_gene_variant 1.0 rifampicin
rpoB 762876 p.Ile1024Leu missense_variant 1.0 rifampicin
rpoB 762879 p.Met1025Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 762887 c.3081G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762905 p.Asp1033Glu missense_variant 1.0 rifampicin
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762938 c.-432G>C upstream_gene_variant 1.0 rifampicin
rpoB 762959 c.3153G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762971 c.-399G>C upstream_gene_variant 1.0 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 1.0 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763005 p.Cys1067Val missense_variant 1.0 rifampicin
rpoC 763013 c.-357C>G upstream_gene_variant 1.0 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763053 c.3247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763058 c.-312C>G upstream_gene_variant 1.0 rifampicin
rpoB 763074 p.Thr1090Val missense_variant 1.0 rifampicin
rpoB 763085 c.3279C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>C upstream_gene_variant 1.0 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763130 p.Glu1108Asp missense_variant 1.0 rifampicin
rpoC 763148 c.-222G>C upstream_gene_variant 1.0 rifampicin
rpoB 763157 c.3351G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763483 c.114G>C synonymous_variant 1.0 rifampicin
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763504 c.135C>T synonymous_variant 1.0 rifampicin
rpoC 763507 c.138G>C synonymous_variant 1.0 rifampicin
rpoC 763517 p.Lys50Arg missense_variant 1.0 rifampicin
rpoC 763528 c.159G>C synonymous_variant 1.0 rifampicin
rpoC 763534 c.165T>C synonymous_variant 1.0 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763550 p.Tyr61Ala missense_variant 1.0 rifampicin
rpoC 763555 c.186C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763578 p.Phe70Tyr missense_variant 1.0 rifampicin
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763619 p.Arg84Lys missense_variant 1.0 rifampicin
rpoC 763622 p.Ala85Ser missense_variant 1.0 rifampicin Uncertain significance
rpoC 763630 c.261G>C synonymous_variant 1.0 rifampicin
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763642 c.273G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763705 c.336G>C synonymous_variant 1.0 rifampicin
rpoC 763708 c.339G>C synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763729 c.360G>C synonymous_variant 1.0 rifampicin
rpoC 764485 c.1116G>C synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764509 c.1140G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764512 c.1143G>C synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.97 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 1.0 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764572 c.1203G>C synonymous_variant 1.0 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764581 c.1212T>C synonymous_variant 1.0 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 1.0 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>C synonymous_variant 1.0 rifampicin
rpoC 764623 c.1254C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764644 c.1275G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764653 c.1284G>C synonymous_variant 1.0 rifampicin
rpoC 764660 p.Val431Ile missense_variant 0.98 rifampicin
rpoC 764687 p.Gln440Glu missense_variant 1.0 rifampicin
rpoC 764692 c.1323C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764695 c.1326T>C synonymous_variant 1.0 rifampicin
rpoC 764701 c.1332C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764731 c.1362G>T synonymous_variant 1.0 rifampicin
rpoC 764737 c.1368G>C synonymous_variant 1.0 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764755 p.Asp462Glu missense_variant 1.0 rifampicin
rpoC 764756 p.Leu463Asn missense_variant 1.0 rifampicin
rpoC 764759 p.Asn464Asp missense_variant 1.0 rifampicin
rpoC 764762 p.His465Tyr missense_variant 1.0 rifampicin Uncertain significance
rpoC 764780 c.1411_1412delAGinsTC synonymous_variant 1.0 rifampicin
rpoC 764785 c.1416C>G synonymous_variant 1.0 rifampicin
rpoC 764797 c.1428G>C synonymous_variant 1.0 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764813 p.Gln482Glu missense_variant 1.0 rifampicin
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764833 c.1464A>G synonymous_variant 1.0 rifampicin
rpoC 764838 p.Val490Ala missense_variant 1.0 rifampicin
rpoC 764857 c.1488G>C synonymous_variant 1.0 rifampicin
rpoC 764858 p.Leu497Met missense_variant 1.0 rifampicin
rpoC 764863 c.1494G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>G synonymous_variant 1.0 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764902 c.1533C>G synonymous_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764913 p.Met515Lys missense_variant 1.0 rifampicin
rpoC 764917 c.1548G>C synonymous_variant 1.0 rifampicin
rpoC 764920 c.1551G>C synonymous_variant 1.0 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764926 c.1557C>T synonymous_variant 1.0 rifampicin
rpoC 764935 c.1566T>C synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764952 p.Val528Ala missense_variant 1.0 rifampicin
rpoC 764962 c.1593G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766345 c.2976T>C synonymous_variant 0.91 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 0.91 rifampicin
rpoC 766375 c.3006C>G synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766434 p.Glu1022Gly missense_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.81_82insAAGCTTGC non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471928 n.84_85delCG non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472029 n.185_194delGGGATGCATG non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472044 n.199_200delGTinsTAGTGTGGGG non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472057 n.212C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472062 n.217G>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472150 n.305T>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472225 n.380C>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441C>A non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.453_461delGTCCGGGTT non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472309 n.464C>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472311 n.466C>T non_coding_transcript_exon_variant 0.97 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472312 n.468_470delGAT non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472328 n.483G>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472330 n.485G>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472447 n.602C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472461 n.616G>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472485 n.640delGinsAT non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472670 n.825_831delGGGTTTCinsAGGGGT non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472685 n.840G>A non_coding_transcript_exon_variant 0.99 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472686 n.841G>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472690 n.845C>T non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 0.99 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472840 n.995A>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472844 n.999C>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472845 n.1000G>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472846 n.1001C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472861 n.1016G>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472874 n.1029C>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473089 n.1244A>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473091 n.1246G>C non_coding_transcript_exon_variant 0.98 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473094 n.1249T>C non_coding_transcript_exon_variant 0.98 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473099 n.1254T>G non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>C non_coding_transcript_exon_variant 0.98 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473109 n.1264T>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473119 n.1274_1275insG non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473122 n.1277T>C non_coding_transcript_exon_variant 0.98 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473132 n.1287T>C non_coding_transcript_exon_variant 0.98 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473292 n.1447_1449delGGAinsTGGG non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474182 n.525C>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474183 n.526T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.529delA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474200 n.545delT non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474286 n.629_634delCTCCTTinsACCTCTTG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474293 n.637_651delCCTCTCCGGAGGAGG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474310 n.655delG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474328 n.671T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474384 n.727C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474487 n.830G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474497 n.840G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474517 n.860C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474798 n.1141C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474825 n.1168G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474920 n.1263G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474921 n.1264C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475027 n.1370G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475033 n.1376G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475057 n.1400G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475061 n.1404C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475063 n.1406A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475076 n.1419C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475094 n.1437C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475108 n.1451C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475110 n.1454_1457delGGCC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475118 n.1461C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475120 n.1463_1464insTCTT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475695 n.2038_2040delGTCinsAACGT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475703 n.2046A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475704 n.2047C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475757 n.2100_2101insGTG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475760 n.2103C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475762 n.2105_2112delGCAAGGGTinsTTGTTGTTGC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476024 n.2367T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476028 n.2372_2375delAACC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476034 n.2377_2378insACAT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476048 n.2391G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476049 n.2392C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476080 n.2423T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476090 n.2434dupT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476097 n.2440C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476100 n.2443A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476116 n.2459A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476307 n.2650A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476309 n.2652G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476524 n.2867_2868delCAinsT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476533 n.2876G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476607 n.2950C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476624 n.2967T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833685 c.144G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833697 c.156C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.92 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833733 c.192C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 1.0 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.92 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
rpsA 1833769 c.228C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833770 p.Asn77Asp missense_variant 1.0 pyrazinamide
rpsA 1833802 p.Glu87Asp missense_variant 1.0 pyrazinamide
rpsA 1833805 c.264C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833835 c.294C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833884 p.Thr115Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1833894 p.Ala118Glu missense_variant 1.0 pyrazinamide
rpsA 1833914 p.Ala125Pro missense_variant 1.0 pyrazinamide
rpsA 1833921 p.Lys127Thr missense_variant 1.0 pyrazinamide
rpsA 1833925 c.384C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833952 c.411C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833973 c.432G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833988 c.447C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833994 c.453G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833997 c.456G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834025 p.Gln162Asp missense_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834040 p.Lys167Gln missense_variant 1.0 pyrazinamide
rpsA 1834046 p.Ile169Leu missense_variant 1.0 pyrazinamide
rpsA 1834054 c.513C>A synonymous_variant 1.0 pyrazinamide
rpsA 1834076 p.Asn179His missense_variant 1.0 pyrazinamide
rpsA 1834093 c.552G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834108 c.567C>A synonymous_variant 1.0 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834246 c.705G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834288 c.747C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834294 c.753G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834327 c.786G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834384 c.843A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834397 p.His286Val missense_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834501 c.960G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834504 c.963G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834523 p.Glu328Gln missense_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834534 c.993C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834552 c.1011G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834556 p.Ala339Thr missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834565 p.Asp342Gln missense_variant 1.0 pyrazinamide
rpsA 1834570 p.Asp343Glu missense_variant 1.0 pyrazinamide
rpsA 1834573 c.1032G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834600 c.1059G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834624 c.1083G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834637 p.Asn366Asp missense_variant 0.95 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 1.0 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 1.0 pyrazinamide
rpsA 1834688 c.1147_1149delAGTinsTCC synonymous_variant 1.0 pyrazinamide
rpsA 1834720 c.1179C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038767 c.1938G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038791 c.1914G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038795 p.Ser637Thr missense_variant 1.0 pyrazinamide
clpC1 4038803 c.1902C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038811 p.Gln632Lys missense_variant 1.0 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038836 c.1869G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038857 c.1848C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038863 c.1842G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038905 c.1800A>C synonymous_variant 1.0 pyrazinamide
clpC1 4038911 c.1794G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>C synonymous_variant 1.0 pyrazinamide
clpC1 4038926 c.1779G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038929 c.1776G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038932 c.1773G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038977 c.1728G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038983 c.1722C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038986 p.Asp573Glu missense_variant 1.0 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038995 c.1708_1710delTTGinsCTC synonymous_variant 1.0 pyrazinamide
clpC1 4039001 p.Asn568Glu missense_variant 1.0 pyrazinamide
clpC1 4039010 c.1695G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039016 c.1689C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039034 c.1671C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039061 c.1644G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039070 c.1635G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039073 c.1632C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039094 c.1611C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039115 p.Lys530Arg missense_variant 0.96 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039136 p.Asp523Glu missense_variant 0.97 pyrazinamide
clpC1 4039139 p.Glu522Asp missense_variant 0.97 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039154 c.1551G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 0.93 pyrazinamide
clpC1 4039190 p.Thr505Ser missense_variant 1.0 pyrazinamide
clpC1 4039195 p.Thr504Ser missense_variant 0.93 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4039236 p.Asn490Ser missense_variant 0.92 pyrazinamide
clpC1 4039241 c.1464G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039244 c.1461G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039262 p.Asp481Glu missense_variant 1.0 pyrazinamide
clpC1 4039266 p.Asp480Gly missense_variant 1.0 pyrazinamide
clpC1 4039682 c.1023C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039685 c.1020C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039714 p.Tyr331His missense_variant 0.96 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039727 c.978C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039730 c.975C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039784 p.Ile307Leu missense_variant 1.0 pyrazinamide
clpC1 4039787 c.918G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039823 c.882T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039831 c.874T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039838 p.Leu289Ile missense_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039871 p.Thr278Gln missense_variant 1.0 pyrazinamide