Run ID: SRR1172857
Sample name:
Date: 2024-05-22T17:17:21.289446
Number of reads: 566017
Percentage reads mapped: 45.32
Median coverage: 12.0
Strain:
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|---|---|---|
La1.2.BCG | M.bovis | None | 0.07 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | embB | p.His312Arg | Mutation from literature | |
pyrazinamide | panD | p.Val138Ala | Mutation from literature | |
streptomycin | rpsL | p.Lys43Arg | Assoc w R | |
rrs | n.462C>T | Uncertain significance | Mutation from literature | |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | fbiC | c.859_861delATCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rpsL | 781687 | p.Lys43Arg | missense_variant | 0.41 | streptomycin | Assoc w R | |
fbiC | 1303789 | c.859_861delATCinsGG | frameshift_variant&missense_variant | 0.6 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.71 | streptomycin | Uncertain significance | Mutation from literature |
panD | 4043869 | p.Val138Ala | missense_variant | 0.4 | pyrazinamide | Mutation from literature | |
embB | 4247448 | p.His312Arg | missense_variant | 0.61 | ethambutol | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 627 | c.627G>A | synonymous_variant | 0.55 | isoniazid | |
dnaA | 693 | c.693A>G | synonymous_variant | 0.4 | isoniazid | Not assoc w R - Interim |
dnaA | 705 | c.705A>G | synonymous_variant | 0.53 | isoniazid | |
dnaA | 708 | c.708T>C | synonymous_variant | 0.47 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 0.44 | isoniazid | Not assoc w R - Interim |
dnaA | 750 | c.750C>G | synonymous_variant | 0.47 | isoniazid | |
dnaA | 756 | c.756T>C | synonymous_variant | 0.47 | isoniazid | |
dnaA | 768 | c.768C>G | synonymous_variant | 0.53 | isoniazid | |
dnaA | 771 | c.771A>C | synonymous_variant | 0.47 | isoniazid | |
dnaA | 777 | c.777A>G | synonymous_variant | 0.52 | isoniazid | |
dnaA | 786 | c.786C>T | synonymous_variant | 0.47 | isoniazid | |
dnaA | 792 | c.792C>T | synonymous_variant | 0.48 | isoniazid | |
dnaA | 795 | c.795A>C | synonymous_variant | 0.43 | isoniazid | Not assoc w R - Interim |
dnaA | 942 | c.942C>G | synonymous_variant | 0.5 | isoniazid | |
dnaA | 945 | c.945G>A | synonymous_variant | 0.48 | isoniazid | |
dnaA | 955 | c.955A>C | synonymous_variant | 0.48 | isoniazid | |
dnaA | 960 | c.960C>A | synonymous_variant | 0.53 | isoniazid | |
dnaA | 963 | c.963C>G | synonymous_variant | 0.5 | isoniazid | |
dnaA | 966 | c.966T>C | synonymous_variant | 0.47 | isoniazid | |
dnaA | 969 | c.969G>A | synonymous_variant | 0.5 | isoniazid | |
dnaA | 975 | c.975G>T | synonymous_variant | 0.47 | isoniazid | |
dnaA | 984 | c.984T>C | synonymous_variant | 0.5 | isoniazid | Not assoc w R - Interim |
dnaA | 1197 | c.1197T>C | synonymous_variant | 0.5 | isoniazid | Not assoc w R - Interim |
dnaA | 1204 | c.1204C>T | synonymous_variant | 0.55 | isoniazid | |
dnaA | 1220 | p.Asn407Ser | missense_variant | 0.48 | isoniazid | |
dnaA | 1230 | c.1230A>G | synonymous_variant | 0.48 | isoniazid | |
dnaA | 1236 | c.1236C>T | synonymous_variant | 0.52 | isoniazid | |
dnaA | 1242 | c.1242G>C | synonymous_variant | 0.56 | isoniazid | |
dnaA | 1245 | c.1245G>C | synonymous_variant | 0.55 | isoniazid | Not assoc w R - Interim |
dnaA | 1254 | c.1254T>C | synonymous_variant | 0.57 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 0.58 | isoniazid | |
dnaA | 1284 | c.1284C>G | synonymous_variant | 0.56 | isoniazid | |
dnaA | 1290 | c.1290G>A | synonymous_variant | 0.46 | isoniazid | |
dnaA | 1293 | c.1293T>C | synonymous_variant | 0.42 | isoniazid | |
dnaA | 1299 | c.1299G>C | synonymous_variant | 0.33 | isoniazid | Not assoc w R - Interim |
dnaA | 1404 | c.1404T>C | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1407 | c.1407T>C | synonymous_variant | 0.32 | isoniazid | |
dnaA | 1413 | c.1413A>C | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1416 | c.1416C>G | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1428 | c.1428C>G | synonymous_variant | 0.32 | isoniazid | |
dnaA | 1449 | c.1449G>A | synonymous_variant | 0.26 | isoniazid | |
dnaA | 1461 | c.1461C>G | synonymous_variant | 0.23 | isoniazid | |
dnaA | 1470 | c.1470C>T | synonymous_variant | 0.23 | isoniazid | |
gyrB | 6136 | c.897G>A | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 6139 | c.900G>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6256 | c.1017G>A | synonymous_variant | 0.56 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6268 | c.1029C>G | synonymous_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6289 | c.1050C>T | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.64 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 0.63 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 6346 | c.1107C>T | synonymous_variant | 0.66 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6362 | c.-940T>C | upstream_gene_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6742 | c.-560A>G | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>G | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6751 | c.-551G>C | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7141 | c.-161T>C | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7147 | c.-155G>C | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7178 | c.-124T>C | upstream_gene_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7186 | c.1947C>G | synonymous_variant | 0.53 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7317 | c.16T>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7324 | c.23_24insAGG | disruptive_inframe_insertion | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7334 | c.33G>C | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7335 | p.Leu12Val | missense_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7347 | c.46_48delGAAinsCG | frameshift_variant&missense_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7355 | c.54T>C | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7361 | c.60C>T | synonymous_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7391 | c.90C>T | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7394 | c.93T>C | synonymous_variant | 0.33 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7532 | c.231T>G | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8121 | c.820T>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8129 | c.828T>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8135 | c.834C>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8156 | c.855T>C | synonymous_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8168 | c.867A>G | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8198 | c.897T>C | synonymous_variant | 0.48 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8225 | c.924T>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 0.47 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8270 | c.969G>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8283 | c.982_984delATCinsCG | frameshift_variant&missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8288 | c.987T>C | synonymous_variant | 0.47 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.47 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8372 | c.1071G>C | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 0.43 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8382 | p.Leu361Met | missense_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8387 | c.1086C>T | synonymous_variant | 0.42 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8391 | c.1090_1092delTATinsCC | frameshift_variant&missense_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8420 | c.1119T>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8576 | c.1275C>G | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8579 | c.1278C>T | synonymous_variant | 0.39 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8588 | c.1287G>A | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8619 | c.1318_1320delTTGinsCA | frameshift_variant&missense_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8624 | c.1323G>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.47 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8891 | c.1590G>A | synonymous_variant | 0.55 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.57 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.57 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8933 | c.1632G>C | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8939 | c.1638T>C | synonymous_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8942 | c.1641G>C | synonymous_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9080 | c.1779G>T | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9089 | c.1788G>C | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9099 | c.1798_1800delTTAinsCG | frameshift_variant&missense_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9104 | c.1803C>G | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9119 | c.1818A>G | synonymous_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9122 | c.1821C>G | synonymous_variant | 0.45 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9161 | c.1860C>G | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9182 | c.1881T>C | synonymous_variant | 0.45 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9191 | c.1890G>C | synonymous_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 0.57 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9204 | p.Ser635Thr | missense_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9224 | c.1923C>T | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9233 | c.1932C>G | synonymous_variant | 0.48 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9239 | c.1938C>T | synonymous_variant | 0.52 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9252 | p.Val651Ile | missense_variant | 0.56 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9291 | c.1990C>T | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.43 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9299 | c.1998G>C | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9300 | p.Ala667Ser | missense_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 0.42 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9308 | p.Asp669Glu | missense_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9323 | c.2022C>G | synonymous_variant | 0.56 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9335 | c.2034G>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
fgd1 | 490827 | c.45C>T | synonymous_variant | 0.53 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490848 | c.66A>G | synonymous_variant | 0.55 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 490851 | c.69A>T | synonymous_variant | 0.55 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490868 | p.Ala29Gly | missense_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490887 | c.105G>A | synonymous_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490890 | c.108C>G | synonymous_variant | 0.53 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490905 | c.123T>C | synonymous_variant | 0.53 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490911 | c.129T>G | synonymous_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490917 | c.135C>G | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491535 | c.753G>C | synonymous_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491542 | c.760T>C | synonymous_variant | 0.55 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491547 | c.765A>C | synonymous_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491550 | c.768T>C | synonymous_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491553 | c.771G>A | synonymous_variant | 0.57 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491601 | c.819T>C | synonymous_variant | 0.55 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491610 | c.828A>G | synonymous_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
mshA | 575576 | c.229C>T | synonymous_variant | 0.38 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575581 | c.234C>T | synonymous_variant | 0.38 | ethionamide | |
isoniazid | ||||||
mshA | 575587 | c.240C>G | synonymous_variant | 0.35 | ethionamide | |
isoniazid | ||||||
mshA | 575590 | c.243T>C | synonymous_variant | 0.38 | ethionamide | |
isoniazid | ||||||
mshA | 575734 | c.387T>G | synonymous_variant | 0.47 | ethionamide | |
isoniazid | ||||||
mshA | 575737 | c.390T>C | synonymous_variant | 0.44 | ethionamide | |
isoniazid | ||||||
mshA | 575746 | c.399C>G | synonymous_variant | 0.39 | ethionamide | |
isoniazid | ||||||
mshA | 575749 | c.402C>A | synonymous_variant | 0.41 | ethionamide | |
isoniazid | ||||||
mshA | 575752 | c.405G>C | synonymous_variant | 0.39 | ethionamide | |
isoniazid | ||||||
mshA | 575755 | c.408G>A | synonymous_variant | 0.39 | ethionamide | |
isoniazid | ||||||
mshA | 575756 | c.409C>T | synonymous_variant | 0.39 | ethionamide | |
isoniazid | ||||||
mshA | 575770 | c.423G>A | synonymous_variant | 0.44 | ethionamide | |
isoniazid | ||||||
mshA | 575771 | p.Val142Ser | missense_variant | 0.44 | ethionamide | |
isoniazid | ||||||
mshA | 575779 | c.432A>G | synonymous_variant | 0.44 | ethionamide | |
isoniazid | ||||||
mshA | 575782 | c.435G>C | synonymous_variant | 0.47 | ethionamide | |
isoniazid | ||||||
mshA | 575809 | c.462C>T | synonymous_variant | 0.5 | ethionamide | |
isoniazid | ||||||
mshA | 575812 | c.465C>T | synonymous_variant | 0.5 | ethionamide | |
isoniazid | ||||||
ccsA | 620385 | c.495G>C | synonymous_variant | 0.47 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
Rv0565c | 657300 | c.171C>G | synonymous_variant | 0.8 | ethionamide | |
Rv0565c | 657318 | c.153T>C | synonymous_variant | 0.77 | ethionamide | |
Rv0565c | 657324 | c.147C>G | synonymous_variant | 0.75 | ethionamide | |
Rv0565c | 657327 | c.144C>G | synonymous_variant | 0.7 | ethionamide | |
Rv0565c | 657337 | p.Arg45Gln | missense_variant | 0.75 | ethionamide | Uncertain significance |
Rv0565c | 657342 | c.129T>C | synonymous_variant | 0.69 | ethionamide | |
Rv0565c | 657347 | c.124A>C | synonymous_variant | 0.64 | ethionamide | |
Rv0565c | 657348 | c.123A>G | synonymous_variant | 0.64 | ethionamide | |
Rv0565c | 657356 | p.Ile39Val | missense_variant | 0.67 | ethionamide | |
Rv0565c | 657372 | c.99G>C | synonymous_variant | 0.55 | ethionamide | |
Rv0565c | 657375 | c.96C>T | synonymous_variant | 0.5 | ethionamide | |
Rv0565c | 657632 | c.-162G>A | upstream_gene_variant | 0.58 | ethionamide | |
Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 0.57 | ethionamide | |
Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 0.55 | ethionamide | |
Rv0565c | 657678 | c.-209_-208delAAinsTC | upstream_gene_variant | 0.62 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAC | upstream_gene_variant | 0.62 | ethionamide | |
Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 0.62 | ethionamide | |
hadA | 731774 | c.-156T>C | upstream_gene_variant | 0.33 | isoniazid | |
hadA | 731789 | c.-141A>G | upstream_gene_variant | 0.32 | isoniazid | |
hadA | 731792 | c.-138G>A | upstream_gene_variant | 0.3 | isoniazid | |
hadA | 731801 | c.-129C>G | upstream_gene_variant | 0.3 | isoniazid | |
hadA | 732272 | p.Ala115Ser | missense_variant | 0.5 | isoniazid | |
hadA | 732295 | c.366G>C | synonymous_variant | 0.47 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 0.53 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.56 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.6 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 0.59 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 0.57 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.59 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.61 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.62 | isoniazid | |
nusG | 734120 | c.-134T>C | upstream_gene_variant | 0.47 | rifampicin | Uncertain significance |
nusG | 734123 | c.-131C>G | upstream_gene_variant | 0.47 | rifampicin | |
nusG | 734129 | c.-125G>C | upstream_gene_variant | 0.44 | rifampicin | |
nusG | 734132 | c.-122G>C | upstream_gene_variant | 0.44 | rifampicin | |
nusG | 734135 | c.-119G>C | upstream_gene_variant | 0.47 | rifampicin | |
nusG | 734144 | c.-110G>C | upstream_gene_variant | 0.39 | rifampicin | |
nusG | 734376 | c.123G>A | synonymous_variant | 0.47 | rifampicin | |
nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 0.55 | rifampicin | |
nusG | 734421 | c.168A>G | synonymous_variant | 0.58 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 0.59 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 0.68 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.69 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.7 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.73 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
nusG | 734499 | c.246G>C | synonymous_variant | 0.77 | rifampicin | |
nusG | 734532 | c.279A>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
nusG | 734556 | c.303C>T | synonymous_variant | 0.58 | rifampicin | |
nusG | 734559 | c.306T>C | synonymous_variant | 0.57 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
nusG | 734589 | c.336G>C | synonymous_variant | 0.42 | rifampicin | |
rpoB | 760101 | c.295T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 760112 | c.306T>C | synonymous_variant | 0.39 | rifampicin | |
rpoB | 760118 | c.312T>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.56 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.62 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.62 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 760298 | c.492G>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.46 | rifampicin | |
rpoB | 760310 | c.504G>C | synonymous_variant | 0.52 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.47 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.5 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.57 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.62 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.62 | rifampicin | |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.74 | rifampicin | |
rpoB | 760412 | c.606C>G | synonymous_variant | 0.74 | rifampicin | |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 760472 | c.666C>T | synonymous_variant | 0.6 | rifampicin | |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.52 | rifampicin | Uncertain significance |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243Thr | missense_variant | 0.52 | rifampicin | |
rpoB | 760541 | c.735G>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.57 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.64 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.4 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 760751 | c.945G>C | synonymous_variant | 0.36 | rifampicin | |
rpoB | 760757 | c.951T>C | synonymous_variant | 0.42 | rifampicin | |
rpoB | 760759 | p.Val318Ala | missense_variant | 0.42 | rifampicin | |
rpoB | 760769 | c.963C>G | synonymous_variant | 0.47 | rifampicin | |
rpoB | 760775 | c.969G>C | synonymous_variant | 0.47 | rifampicin | |
rpoB | 760776 | c.970_972delTCGinsAGC | synonymous_variant | 0.47 | rifampicin | |
rpoB | 760859 | c.1053T>C | synonymous_variant | 0.57 | rifampicin | |
rpoB | 760862 | c.1056G>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 760869 | p.Val355Ile | missense_variant | 0.5 | rifampicin | Uncertain significance |
rpoB | 760886 | c.1080A>G | synonymous_variant | 0.65 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.59 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 760931 | c.1125C>G | synonymous_variant | 0.62 | rifampicin | |
rpoB | 760934 | c.1128C>T | synonymous_variant | 0.68 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.61 | rifampicin | |
rpoB | 761006 | c.1200C>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.74 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.74 | rifampicin | |
rpoB | 761129 | c.1323G>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 761132 | c.1326G>T | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoB | 761153 | c.1347G>C | synonymous_variant | 0.65 | rifampicin | |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoB | 761207 | c.1401C>T | synonymous_variant | 0.75 | rifampicin | |
rpoB | 761213 | c.1407G>C | synonymous_variant | 0.75 | rifampicin | |
rpoB | 761219 | c.1413G>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 761306 | c.1500C>G | synonymous_variant | 0.67 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 761330 | c.1524G>C | synonymous_variant | 0.53 | rifampicin | |
rpoB | 761354 | c.1548C>T | synonymous_variant | 0.42 | rifampicin | |
rpoB | 761360 | c.1554T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.71 | rifampicin | |
rpoB | 761531 | c.1725C>G | synonymous_variant | 0.68 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 761588 | c.1782C>T | synonymous_variant | 0.75 | rifampicin | |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.7 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.57 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.64 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.69 | rifampicin | |
rpoB | 761815 | p.Ala670Glu | missense_variant | 0.69 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.56 | rifampicin | |
rpoB | 761848 | p.Cys681Ser | missense_variant | 0.43 | rifampicin | |
rpoB | 761852 | c.2046C>G | synonymous_variant | 0.47 | rifampicin | |
rpoB | 761858 | c.2052G>C | synonymous_variant | 0.44 | rifampicin | |
rpoB | 761873 | c.2067A>C | synonymous_variant | 0.46 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.43 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 0.42 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.43 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.43 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.43 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.43 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 762008 | c.2202C>T | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.8 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.61 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.64 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.56 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.56 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 762206 | c.2400C>G | synonymous_variant | 0.65 | rifampicin | |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 762246 | c.2440C>T | synonymous_variant | 0.61 | rifampicin | |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.59 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.6 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.62 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 762314 | c.2508C>T | synonymous_variant | 0.57 | rifampicin | |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.56 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.53 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.56 | rifampicin | |
rpoB | 762449 | c.2643C>A | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 762467 | c.-903C>T | upstream_gene_variant | 0.44 | rifampicin | |
rpoB | 762488 | c.2682G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 762489 | p.Val895Gln | missense_variant | 0.42 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.48 | rifampicin | |
rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 0.48 | rifampicin | |
rpoC | 762521 | c.-849C>T | upstream_gene_variant | 0.48 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.39 | rifampicin | |
rpoB | 762827 | c.3021G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 762860 | c.3054G>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.71 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoC | 763013 | c.-357C>G | upstream_gene_variant | 0.72 | rifampicin | |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>G | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 763067 | c.-303C>G | upstream_gene_variant | 0.58 | rifampicin | |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoB | 763136 | c.3330C>T | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.63 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.66 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 763190 | c.-180C>T | upstream_gene_variant | 0.61 | rifampicin | |
rpoC | 763202 | c.-168A>G | upstream_gene_variant | 0.54 | rifampicin | |
rpoC | 763205 | c.-165G>C | upstream_gene_variant | 0.48 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 0.48 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.52 | rifampicin | |
rpoB | 763227 | c.3421C>T | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 763238 | c.3432T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 763253 | c.-117G>C | upstream_gene_variant | 0.37 | rifampicin | |
rpoC | 763256 | c.-114G>A | upstream_gene_variant | 0.37 | rifampicin | |
rpoC | 763402 | c.33C>G | synonymous_variant | 0.66 | rifampicin | |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 0.62 | rifampicin | |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.67 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.49 | rifampicin | |
rpoC | 763492 | c.123G>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 763606 | c.237C>T | synonymous_variant | 0.72 | rifampicin | |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.61 | rifampicin | |
rpoC | 763657 | c.288G>A | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.51 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.56 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.59 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.59 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 763774 | c.405G>C | synonymous_variant | 0.56 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 763816 | c.447C>G | synonymous_variant | 0.52 | rifampicin | |
rpoC | 763853 | p.Val162Ile | missense_variant | 0.32 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.38 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.38 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 763900 | c.531G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.56 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 764102 | p.Val245Ile | missense_variant | 0.72 | rifampicin | |
rpoC | 764112 | p.Tyr248Phe | missense_variant | 0.71 | rifampicin | |
rpoC | 764116 | c.747C>T | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.74 | rifampicin | |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Ile | missense_variant | 0.47 | rifampicin | |
rpoC | 764203 | c.834G>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 764215 | c.846A>G | synonymous_variant | 0.58 | rifampicin | |
rpoC | 764236 | c.867G>A | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 764248 | c.879C>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.65 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.6 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.54 | rifampicin | |
rpoC | 764272 | c.903G>C | synonymous_variant | 0.57 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 764338 | c.969G>A | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036A>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 764419 | c.1050C>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 764428 | c.1059G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764489 | c.1120C>T | synonymous_variant | 0.55 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 764548 | c.1179G>A | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764551 | c.1182G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764593 | c.1224C>T | synonymous_variant | 0.45 | rifampicin | |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>C | synonymous_variant | 0.8 | rifampicin | |
rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 0.8 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.53 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519T>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.76 | rifampicin | |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R |
rpoC | 765007 | c.1638T>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 765008 | c.1639T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 765011 | c.1642_1643delAGinsTC | synonymous_variant | 0.47 | rifampicin | |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 765034 | c.1665T>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 765040 | c.1671T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 765055 | c.1686C>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 765073 | c.1704G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
rpoC | 765529 | c.2160C>T | synonymous_variant | 0.88 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.86 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.86 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.81 | rifampicin | |
rpoC | 765580 | c.2211G>C | synonymous_variant | 0.76 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.67 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 765628 | c.2259G>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.56 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>T | synonymous_variant | 0.69 | rifampicin | |
rpoC | 765751 | c.2382C>G | synonymous_variant | 0.71 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 0.71 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.67 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.67 | rifampicin | |
rpoC | 765787 | c.2418C>T | synonymous_variant | 0.69 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.69 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.69 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 765850 | c.2481G>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.62 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.67 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 765937 | c.2568T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>G | synonymous_variant | 0.8 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.75 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.76 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 0.72 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.74 | rifampicin | |
rpoC | 766054 | c.2685C>G | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.71 | rifampicin | |
rpoC | 766096 | c.2727G>C | synonymous_variant | 0.78 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 0.71 | rifampicin | |
rpoC | 766132 | c.2763C>T | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766135 | c.2766G>A | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 766141 | c.2772C>T | synonymous_variant | 0.62 | rifampicin | |
rpoC | 766142 | c.2773C>T | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 766357 | c.2988C>T | synonymous_variant | 0.43 | rifampicin | |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.45 | rifampicin | |
rpoC | 766366 | c.2997C>G | synonymous_variant | 0.43 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.42 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 766390 | c.3021C>T | synonymous_variant | 0.42 | rifampicin | |
rpoC | 766393 | c.3024C>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 766408 | c.3039C>G | synonymous_variant | 0.5 | rifampicin | |
rpoC | 766411 | c.3042C>G | synonymous_variant | 0.47 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 766462 | c.3093G>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 0.62 | rifampicin | |
rpoC | 766484 | c.3115_3117delGTAinsAC | frameshift_variant&missense_variant | 0.62 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.62 | rifampicin | |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.65 | rifampicin | |
rpoC | 766540 | p.Asp1057Glu | missense_variant | 0.5 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 766630 | c.3261G>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 766795 | c.3426C>T | synonymous_variant | 0.64 | rifampicin | |
rpoC | 766801 | c.3432C>G | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.7 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.7 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.87 | rifampicin | |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.6 | rifampicin | |
rpoC | 767033 | c.3664_3666delTCGinsAGC | synonymous_variant | 0.45 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.43 | rifampicin | |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.57 | rifampicin | |
rpoC | 767158 | c.3789T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.56 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 767212 | c.3843G>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 776672 | c.1809G>C | synonymous_variant | 0.43 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776675 | c.1806G>A | synonymous_variant | 0.43 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776684 | c.1797G>A | synonymous_variant | 0.43 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776687 | p.Trp598Phe | missense_variant | 0.41 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776695 | p.Val596Ile | missense_variant | 0.39 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776738 | c.1743C>T | synonymous_variant | 0.41 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777164 | c.1317C>G | synonymous_variant | 0.54 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777170 | c.1311T>C | synonymous_variant | 0.53 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777176 | p.Glu435Asp | missense_variant | 0.5 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777191 | c.1290C>G | synonymous_variant | 0.5 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777194 | c.1287A>G | synonymous_variant | 0.47 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777206 | c.1275A>G | synonymous_variant | 0.44 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777212 | c.1267_1269delGCCinsAG | frameshift_variant&missense_variant | 0.37 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 777215 | c.1266C>G | synonymous_variant | 0.32 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777218 | c.1263G>A | synonymous_variant | 0.32 | clofazimine | |
bedaquiline | ||||||
rpsL | 781628 | c.69T>C | synonymous_variant | 0.57 | streptomycin | Not assoc w R - Interim |
rpsL | 781631 | c.72G>C | synonymous_variant | 0.56 | streptomycin | |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.64 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.63 | streptomycin | |
rpsL | 781700 | c.141G>C | synonymous_variant | 0.65 | streptomycin | |
rpsL | 781703 | c.144G>T | synonymous_variant | 0.68 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.67 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.72 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.69 | streptomycin | |
rpsL | 781742 | c.183C>T | synonymous_variant | 0.69 | streptomycin | |
rpsL | 781748 | c.189C>G | synonymous_variant | 0.67 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.67 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.69 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.59 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 0.59 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 0.54 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.56 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.54 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.54 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.54 | streptomycin | |
rpsL | 781877 | c.318T>C | synonymous_variant | 0.56 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.57 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.58 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.58 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.73 | streptomycin | Uncertain significance |
rplC | 800516 | c.-293G>T | upstream_gene_variant | 0.67 | linezolid | |
rplC | 800537 | c.-272C>T | upstream_gene_variant | 0.62 | linezolid | |
rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.62 | linezolid | |
rplC | 800546 | c.-263T>G | upstream_gene_variant | 0.67 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.67 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.64 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.71 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.71 | linezolid | |
rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.75 | linezolid | |
rplC | 800648 | c.-161A>T | upstream_gene_variant | 0.72 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.76 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.78 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.78 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.72 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.68 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.72 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.73 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.68 | linezolid | |
rplC | 800794 | c.-15A>G | upstream_gene_variant | 0.62 | linezolid | |
rplC | 800796 | c.-13A>G | upstream_gene_variant | 0.62 | linezolid | |
rplC | 800798 | c.-10_-9delGG | upstream_gene_variant | 0.6 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 0.59 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 0.62 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 0.53 | linezolid | |
rplC | 801348 | c.540T>G | synonymous_variant | 0.46 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 0.5 | linezolid | |
rplC | 801367 | p.Ala187Thr | missense_variant | 0.5 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 0.4 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 0.38 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 0.47 | linezolid | |
fbiC | 1303521 | c.591C>T | synonymous_variant | 0.53 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303530 | c.600G>A | synonymous_variant | 0.64 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303534 | p.Ser202Ala | missense_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303539 | c.609G>C | synonymous_variant | 0.73 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.75 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.72 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.8 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303602 | c.672A>G | synonymous_variant | 0.75 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303605 | c.675C>G | synonymous_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303608 | c.678G>A | synonymous_variant | 0.6 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303686 | c.756C>G | synonymous_variant | 0.53 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303695 | c.765T>C | synonymous_variant | 0.53 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303704 | c.774T>C | synonymous_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.61 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303728 | c.798G>A | synonymous_variant | 0.71 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303731 | c.801A>C | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303732 | p.Ser268Ala | missense_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303737 | c.807G>A | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303746 | c.816T>C | synonymous_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303749 | c.819G>C | synonymous_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303752 | c.822A>G | synonymous_variant | 0.63 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303755 | c.825T>C | synonymous_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303761 | c.831T>C | synonymous_variant | 0.68 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303785 | c.855G>C | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303797 | c.867A>G | synonymous_variant | 0.65 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.66 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303845 | c.915C>G | synonymous_variant | 0.68 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.68 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.69 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.65 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304553 | c.1623C>T | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304565 | c.1635C>G | synonymous_variant | 0.73 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304568 | c.1638T>C | synonymous_variant | 0.75 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.78 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304613 | c.1683T>C | synonymous_variant | 0.6 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.59 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.57 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304691 | c.1761G>C | synonymous_variant | 0.6 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304694 | c.1764A>C | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304703 | c.1773C>G | synonymous_variant | 0.57 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.75 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304787 | c.1857T>G | synonymous_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.76 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.76 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.79 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.81 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304832 | c.1902C>T | synonymous_variant | 0.79 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304891 | p.Ile654Thr | missense_variant | 0.75 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.75 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304907 | c.1977C>G | synonymous_variant | 0.71 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304910 | c.1980G>C | synonymous_variant | 0.71 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.69 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.68 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.73 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304983 | c.2053C>T | synonymous_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304995 | p.Leu689Met | missense_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305006 | c.2076A>G | synonymous_variant | 0.69 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305012 | c.2082G>C | synonymous_variant | 0.58 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305015 | c.2085G>C | synonymous_variant | 0.58 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305021 | c.2091C>G | synonymous_variant | 0.54 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305384 | c.2454G>C | synonymous_variant | 0.47 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305396 | c.2466C>G | synonymous_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305405 | c.2475A>G | synonymous_variant | 0.47 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | ||||||
sigE | 1365033 | c.621G>A | synonymous_variant | 0.38 | pyrazinamide | |
sigE | 1365036 | c.624T>C | synonymous_variant | 0.38 | pyrazinamide | |
sigE | 1365042 | c.630G>C | synonymous_variant | 0.44 | pyrazinamide | |
sigE | 1365057 | c.645C>T | synonymous_variant | 0.47 | pyrazinamide | |
sigE | 1365063 | c.651A>C | synonymous_variant | 0.5 | pyrazinamide | |
sigE | 1365084 | c.672G>C | synonymous_variant | 0.43 | pyrazinamide | |
sigE | 1365087 | c.675A>C | synonymous_variant | 0.43 | pyrazinamide | |
sigE | 1365090 | c.678T>C | synonymous_variant | 0.46 | pyrazinamide | |
sigE | 1365096 | c.684G>C | synonymous_variant | 0.55 | pyrazinamide | |
sigE | 1365099 | c.687A>C | synonymous_variant | 0.55 | pyrazinamide | |
atpE | 1461170 | c.126A>G | synonymous_variant | 0.45 | bedaquiline | |
atpE | 1461185 | c.141G>T | synonymous_variant | 0.52 | bedaquiline | |
atpE | 1461197 | c.153A>G | synonymous_variant | 0.48 | bedaquiline | |
atpE | 1461219 | c.175T>C | synonymous_variant | 0.36 | bedaquiline | |
atpE | 1461233 | c.189A>C | synonymous_variant | 0.36 | bedaquiline | |
atpE | 1461251 | c.207G>C | synonymous_variant | 0.36 | bedaquiline | |
atpE | 1461254 | c.210T>C | synonymous_variant | 0.38 | bedaquiline | |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 0.57 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 0.52 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 0.54 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.54 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 0.43 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.45 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472028 | n.183A>T | non_coding_transcript_exon_variant | 0.37 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472029 | n.184C>T | non_coding_transcript_exon_variant | 0.37 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472030 | n.185G>T | non_coding_transcript_exon_variant | 0.37 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472031 | n.186G>A | non_coding_transcript_exon_variant | 0.39 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472033 | n.188A>G | non_coding_transcript_exon_variant | 0.39 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 0.39 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472044 | n.199G>T | non_coding_transcript_exon_variant | 0.47 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472045 | n.200T>A | non_coding_transcript_exon_variant | 0.5 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.55 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.55 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.6 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.59 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.55 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.54 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.51 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.53 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.59 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.59 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.64 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.66 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.72 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrl | 1473677 | n.20C>G | non_coding_transcript_exon_variant | 0.47 | capreomycin | |
linezolid | ||||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.71 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.72 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473945 | n.288T>A | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473946 | n.289A>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 0.59 | capreomycin | |
linezolid | ||||||
rrl | 1473987 | n.330G>A | non_coding_transcript_exon_variant | 0.59 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474093 | n.436G>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
linezolid | ||||||
rrl | 1474099 | n.442G>A | non_coding_transcript_exon_variant | 0.59 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.6 | capreomycin | |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.73 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.72 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.73 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474291 | n.635_649delTTCCTCTCCGGAGGA | non_coding_transcript_exon_variant | 0.54 | capreomycin | |
linezolid | ||||||
rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.48 | capreomycin | |
linezolid | ||||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.59 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 0.65 | capreomycin | |
linezolid | ||||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474904 | n.1247G>A | non_coding_transcript_exon_variant | 0.5 | capreomycin | |
linezolid | ||||||
rrl | 1474956 | n.1299C>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1474960 | n.1303C>G | non_coding_transcript_exon_variant | 0.4 | capreomycin | |
linezolid | ||||||
rrl | 1474963 | n.1306G>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474964 | n.1307T>A | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1474965 | n.1308G>C | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1474970 | n.1313G>A | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1475006 | n.1349A>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | |
linezolid | ||||||
rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 0.65 | capreomycin | |
linezolid | ||||||
rrl | 1475206 | n.1549C>T | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475209 | n.1552G>C | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475249 | n.1592T>C | non_coding_transcript_exon_variant | 0.66 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475252 | n.1595C>T | non_coding_transcript_exon_variant | 0.66 | capreomycin | |
linezolid | ||||||
rrl | 1475266 | n.1609T>C | non_coding_transcript_exon_variant | 0.65 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475267 | n.1610G>A | non_coding_transcript_exon_variant | 0.65 | capreomycin | |
linezolid | ||||||
rrl | 1475275 | n.1618C>T | non_coding_transcript_exon_variant | 0.65 | capreomycin | |
linezolid | ||||||
rrl | 1475276 | n.1619T>C | non_coding_transcript_exon_variant | 0.65 | capreomycin | |
linezolid | ||||||
rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 0.65 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475313 | n.1656G>A | non_coding_transcript_exon_variant | 0.73 | capreomycin | |
linezolid | ||||||
rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 0.75 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
linezolid | ||||||
rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 0.59 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475436 | n.1779C>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.73 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.78 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.79 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.71 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.71 | capreomycin | |
linezolid | ||||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.68 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1475761 | n.2104_2106delCGCinsGT | non_coding_transcript_exon_variant | 0.74 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 0.72 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.52 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476031 | n.2374C>T | non_coding_transcript_exon_variant | 0.54 | capreomycin | |
linezolid | ||||||
rrl | 1476032 | n.2375C>A | non_coding_transcript_exon_variant | 0.57 | capreomycin | |
linezolid | ||||||
rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476034 | n.2377C>A | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | |
linezolid | ||||||
rrl | 1476048 | n.2391G>A | non_coding_transcript_exon_variant | 0.55 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 0.6 | capreomycin | |
linezolid | ||||||
rrl | 1476095 | n.2438C>G | non_coding_transcript_exon_variant | 0.58 | capreomycin | |
linezolid | ||||||
rrl | 1476105 | n.2448_2449delGAinsT | non_coding_transcript_exon_variant | 0.58 | capreomycin | |
linezolid | ||||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476117 | n.2460G>C | non_coding_transcript_exon_variant | 0.6 | capreomycin | |
linezolid | ||||||
rrl | 1476214 | n.2557G>A | non_coding_transcript_exon_variant | 0.62 | capreomycin | |
linezolid | ||||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.65 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.65 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.68 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.71 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.74 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.64 | capreomycin | |
linezolid | ||||||
rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.64 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.64 | capreomycin | |
linezolid | ||||||
rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 0.48 | capreomycin | |
linezolid | ||||||
rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 0.46 | capreomycin | |
linezolid | ||||||
rrl | 1476733 | n.3076C>T | non_coding_transcript_exon_variant | 0.46 | capreomycin | |
linezolid | ||||||
rrl | 1476750 | n.3093T>C | non_coding_transcript_exon_variant | 0.48 | capreomycin | |
linezolid | ||||||
rrl | 1476755 | n.3098G>A | non_coding_transcript_exon_variant | 0.48 | capreomycin | |
linezolid | ||||||
rrl | 1476759 | n.3102T>C | non_coding_transcript_exon_variant | 0.47 | capreomycin | |
linezolid | ||||||
inhA | 1673547 | c.-655T>C | upstream_gene_variant | 0.39 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673548 | p.Ala37Thr | missense_variant | 0.39 | ethionamide | |
isoniazid | ||||||
inhA | 1673679 | c.-523T>G | upstream_gene_variant | 0.43 | ethionamide | |
isoniazid | ||||||
inhA | 1673685 | c.-517C>T | upstream_gene_variant | 0.4 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673716 | p.Ala93Lys | missense_variant | 0.42 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673733 | p.Met98Ile | missense_variant | 0.5 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673941 | p.Ala168Ser | missense_variant | 0.67 | ethionamide | |
isoniazid | ||||||
inhA | 1673946 | c.-256C>G | upstream_gene_variant | 0.62 | ethionamide | |
isoniazid | ||||||
inhA | 1673955 | c.-247G>C | upstream_gene_variant | 0.62 | ethionamide | |
isoniazid | ||||||
inhA | 1673961 | c.-241A>C | upstream_gene_variant | 0.57 | ethionamide | |
isoniazid | ||||||
inhA | 1673985 | c.-217C>G | upstream_gene_variant | 0.5 | ethionamide | |
isoniazid | ||||||
fabG1 | 1674006 | p.Asp189Glu | missense_variant | 0.53 | ethionamide | |
isoniazid | ||||||
inhA | 1674015 | c.-187C>T | upstream_gene_variant | 0.46 | ethionamide | |
isoniazid | Uncertain significance | |||||
inhA | 1674018 | c.-184G>C | upstream_gene_variant | 0.46 | ethionamide | |
isoniazid | ||||||
inhA | 1674021 | c.-181G>C | upstream_gene_variant | 0.5 | ethionamide | |
isoniazid | ||||||
inhA | 1674024 | c.-178T>C | upstream_gene_variant | 0.5 | ethionamide | |
isoniazid | ||||||
inhA | 1674063 | c.-139G>C | upstream_gene_variant | 0.7 | ethionamide | |
isoniazid | ||||||
fabG1 | 1674079 | p.Pro214Ala | missense_variant | 0.83 | ethionamide | |
isoniazid | ||||||
inhA | 1674624 | c.423A>C | synonymous_variant | 0.58 | ethionamide | |
isoniazid | ||||||
inhA | 1674630 | c.429C>G | synonymous_variant | 0.57 | ethionamide | |
isoniazid | ||||||
inhA | 1674660 | c.459G>C | synonymous_variant | 0.54 | ethionamide | |
isoniazid | ||||||
inhA | 1674672 | c.471C>G | synonymous_variant | 0.5 | ethionamide | |
isoniazid | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 0.55 | ethionamide | |
isoniazid | ||||||
inhA | 1674708 | c.507G>A | synonymous_variant | 0.47 | ethionamide | |
isoniazid | ||||||
inhA | 1674801 | c.600T>C | synonymous_variant | 0.39 | ethionamide | |
isoniazid | ||||||
inhA | 1674822 | c.621C>G | synonymous_variant | 0.4 | ethionamide | |
isoniazid | ||||||
inhA | 1674828 | c.627G>A | synonymous_variant | 0.38 | ethionamide | |
isoniazid | ||||||
inhA | 1674846 | p.Ile215Met | missense_variant | 0.52 | ethionamide | |
isoniazid | ||||||
inhA | 1674864 | c.663C>T | synonymous_variant | 0.57 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674870 | c.669T>C | synonymous_variant | 0.65 | ethionamide | |
isoniazid | ||||||
inhA | 1674879 | c.678T>C | synonymous_variant | 0.68 | ethionamide | |
isoniazid | ||||||
inhA | 1674900 | c.699G>A | synonymous_variant | 0.6 | ethionamide | |
isoniazid | ||||||
inhA | 1674903 | c.702T>C | synonymous_variant | 0.63 | ethionamide | |
isoniazid | ||||||
inhA | 1674904 | p.Ala235Pro | missense_variant | 0.67 | ethionamide | |
isoniazid | ||||||
inhA | 1674909 | c.708G>A | synonymous_variant | 0.71 | ethionamide | |
isoniazid | ||||||
inhA | 1674942 | c.741T>G | synonymous_variant | 0.64 | ethionamide | |
isoniazid | ||||||
rpsA | 1833554 | p.Thr5Ala | missense_variant | 0.6 | pyrazinamide | Uncertain significance |
rpsA | 1833568 | c.27G>C | synonymous_variant | 0.57 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.56 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.56 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.57 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1833721 | c.180A>G | synonymous_variant | 0.63 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.61 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.63 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.63 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.63 | pyrazinamide | |
rpsA | 1833748 | c.207C>G | synonymous_variant | 0.68 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.67 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.67 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.64 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.52 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.58 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.52 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.53 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.57 | pyrazinamide | |
rpsA | 1833971 | c.430C>T | synonymous_variant | 0.58 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.6 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.67 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.62 | pyrazinamide | |
rpsA | 1834096 | c.555G>C | synonymous_variant | 0.69 | pyrazinamide | |
rpsA | 1834099 | c.558C>G | synonymous_variant | 0.75 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.69 | pyrazinamide | |
rpsA | 1834105 | c.564C>G | synonymous_variant | 0.69 | pyrazinamide | |
rpsA | 1834108 | c.567C>G | synonymous_variant | 0.75 | pyrazinamide | |
rpsA | 1834150 | c.609G>C | synonymous_variant | 0.71 | pyrazinamide | |
rpsA | 1834153 | c.612T>C | synonymous_variant | 0.64 | pyrazinamide | |
rpsA | 1834154 | c.613_615delAACinsCG | frameshift_variant&missense_variant | 0.64 | pyrazinamide | Uncertain significance |
rpsA | 1834162 | c.621A>G | synonymous_variant | 0.6 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834165 | c.624A>G | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1834169 | p.Thr210Ala | missense_variant | 0.5 | pyrazinamide | Uncertain significance |
rpsA | 1834177 | c.636A>C | synonymous_variant | 0.55 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834189 | c.648G>C | synonymous_variant | 0.53 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.55 | pyrazinamide | |
rpsA | 1834210 | c.669C>T | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.42 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834264 | c.723G>C | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1834303 | c.762T>C | synonymous_variant | 0.56 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.55 | pyrazinamide | |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.6 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.52 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.57 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.52 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.48 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.48 | pyrazinamide | |
rpsA | 1834510 | c.969C>T | synonymous_variant | 0.53 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834513 | c.972C>G | synonymous_variant | 0.58 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.61 | pyrazinamide | |
rpsA | 1834540 | c.999G>C | synonymous_variant | 0.71 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.72 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.64 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.6 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.56 | pyrazinamide | |
rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.48 | pyrazinamide | |
rpsA | 1834684 | c.1143C>T | synonymous_variant | 0.52 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Ser | missense_variant | 0.43 | pyrazinamide | |
rpsA | 1834738 | c.1197A>G | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.58 | pyrazinamide | |
rpsA | 1834765 | p.Glu408Asp | missense_variant | 0.5 | pyrazinamide | |
rpsA | 1834775 | p.Ala412Thr | missense_variant | 0.5 | pyrazinamide | |
tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.52 | linezolid | |
tsnR | 1853370 | c.-236_-234delGCAinsTG | upstream_gene_variant | 0.54 | linezolid | |
tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.59 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.57 | linezolid | |
tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.55 | linezolid | |
tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.52 | linezolid | |
tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 0.53 | linezolid | |
tsnR | 1853447 | c.-159C>G | upstream_gene_variant | 0.57 | linezolid | |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
bacA | 2064972 | c.-244T>C | upstream_gene_variant | 0.73 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064978 | c.-250G>C | upstream_gene_variant | 0.75 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064979 | c.-251C>T | upstream_gene_variant | 0.75 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064984 | c.-256A>G | upstream_gene_variant | 0.75 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064993 | c.-265T>C | upstream_gene_variant | 0.86 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
ndh | 2102686 | c.357G>C | synonymous_variant | 0.38 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102695 | c.348C>T | synonymous_variant | 0.38 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102700 | c.343C>T | synonymous_variant | 0.4 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102710 | c.333C>T | synonymous_variant | 0.35 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
katG | 2155677 | c.435C>G | synonymous_variant | 0.79 | isoniazid | |
katG | 2155680 | c.432G>C | synonymous_variant | 0.8 | isoniazid | |
katG | 2155691 | c.421T>C | synonymous_variant | 0.93 | isoniazid | |
katG | 2155695 | c.417C>G | synonymous_variant | 0.94 | isoniazid | |
katG | 2155704 | c.408C>G | synonymous_variant | 0.94 | isoniazid | |
katG | 2155716 | c.396T>G | synonymous_variant | 0.82 | isoniazid | |
katG | 2155722 | c.390G>C | synonymous_variant | 0.76 | isoniazid | |
katG | 2155728 | c.384G>C | synonymous_variant | 0.71 | isoniazid | |
katG | 2155740 | p.Gly124Gln | missense_variant | 0.56 | isoniazid | |
katG | 2155743 | c.369G>C | synonymous_variant | 0.56 | isoniazid | |
PPE35 | 2170892 | c.-280G>A | upstream_gene_variant | 0.95 | pyrazinamide | |
pncA | 2289930 | c.-689A>G | upstream_gene_variant | 0.44 | pyrazinamide | |
pncA | 2289943 | c.-702T>G | upstream_gene_variant | 0.47 | pyrazinamide | |
pncA | 2289948 | c.-707C>T | upstream_gene_variant | 0.47 | pyrazinamide | |
pncA | 2289949 | c.-708A>G | upstream_gene_variant | 0.47 | pyrazinamide | |
pncA | 2289987 | c.-746C>T | upstream_gene_variant | 0.56 | pyrazinamide | |
pncA | 2289991 | c.-750G>C | upstream_gene_variant | 0.53 | pyrazinamide | |
pncA | 2289994 | c.-753A>G | upstream_gene_variant | 0.53 | pyrazinamide | |
pncA | 2289997 | c.-756G>C | upstream_gene_variant | 0.6 | pyrazinamide | |
pncA | 2290009 | c.-768A>G | upstream_gene_variant | 0.69 | pyrazinamide | |
pncA | 2290015 | c.-774A>C | upstream_gene_variant | 0.69 | pyrazinamide | |
pncA | 2290024 | c.-783C>G | upstream_gene_variant | 0.67 | pyrazinamide | |
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.75 | isoniazid | |
kasA | 2517989 | c.-126T>C | upstream_gene_variant | 0.64 | isoniazid | |
kasA | 2517993 | c.-122G>T | upstream_gene_variant | 0.62 | isoniazid | |
kasA | 2518019 | c.-96A>G | upstream_gene_variant | 0.44 | isoniazid | |
kasA | 2518138 | c.24T>C | synonymous_variant | 0.43 | isoniazid | |
kasA | 2518146 | p.Phe11Tyr | missense_variant | 0.47 | isoniazid | |
kasA | 2518162 | c.48G>A | synonymous_variant | 0.59 | isoniazid | |
kasA | 2518174 | c.60A>G | synonymous_variant | 0.59 | isoniazid | |
kasA | 2518190 | p.Ser26Ala | missense_variant | 0.5 | isoniazid | |
kasA | 2518199 | p.Ile29Val | missense_variant | 0.5 | isoniazid | |
kasA | 2518220 | c.106C>T | synonymous_variant | 0.43 | isoniazid | |
kasA | 2518234 | c.120G>A | synonymous_variant | 0.39 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.64 | isoniazid | |
kasA | 2518678 | c.564C>T | synonymous_variant | 0.58 | isoniazid | |
kasA | 2518684 | c.570C>G | synonymous_variant | 0.57 | isoniazid | |
kasA | 2518696 | c.582C>G | synonymous_variant | 0.57 | isoniazid | |
kasA | 2518702 | c.588C>T | synonymous_variant | 0.57 | isoniazid | |
kasA | 2518705 | c.591T>C | synonymous_variant | 0.57 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 0.62 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.64 | isoniazid | |
kasA | 2518732 | c.618C>G | synonymous_variant | 0.58 | isoniazid | |
kasA | 2518744 | c.630C>T | synonymous_variant | 0.56 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.56 | isoniazid | |
kasA | 2518768 | c.654C>T | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518777 | c.663C>T | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518789 | c.675G>C | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518792 | c.678C>A | synonymous_variant | 0.43 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.43 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.56 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518879 | c.765A>G | synonymous_variant | 0.52 | isoniazid | |
kasA | 2518885 | c.771T>C | synonymous_variant | 0.52 | isoniazid | |
kasA | 2518898 | c.784T>C | synonymous_variant | 0.52 | isoniazid | |
kasA | 2519072 | p.Ala320Thr | missense_variant | 0.69 | isoniazid | |
kasA | 2519107 | c.993T>C | synonymous_variant | 0.85 | isoniazid | |
kasA | 2519108 | c.994_996delGATinsCG | frameshift_variant&missense_variant | 0.85 | isoniazid | |
kasA | 2519122 | c.1008G>C | synonymous_variant | 0.75 | isoniazid | |
kasA | 2519137 | c.1023T>G | synonymous_variant | 0.64 | isoniazid | |
kasA | 2519158 | c.1044C>T | synonymous_variant | 0.6 | isoniazid | |
kasA | 2519167 | c.1053T>G | synonymous_variant | 0.69 | isoniazid | |
kasA | 2519173 | c.1059C>G | synonymous_variant | 0.57 | isoniazid | |
ahpC | 2726336 | c.144G>C | synonymous_variant | 0.37 | isoniazid | |
ahpC | 2726348 | c.156T>C | synonymous_variant | 0.5 | isoniazid | |
ahpC | 2726357 | c.165A>G | synonymous_variant | 0.5 | isoniazid | Not assoc w R - Interim |
ahpC | 2726564 | c.372C>G | synonymous_variant | 0.53 | isoniazid | Not assoc w R - Interim |
ahpC | 2726591 | c.399C>G | synonymous_variant | 0.67 | isoniazid | |
ahpC | 2726593 | p.Val134Ala | missense_variant | 0.67 | isoniazid | |
ahpC | 2726600 | c.408T>C | synonymous_variant | 0.65 | isoniazid | |
ahpC | 2726601 | p.Ile137Leu | missense_variant | 0.68 | isoniazid | |
ahpC | 2726638 | p.Ala149Val | missense_variant | 0.68 | isoniazid | |
ahpC | 2726645 | c.453C>G | synonymous_variant | 0.67 | isoniazid | |
ahpC | 2726657 | c.465A>C | synonymous_variant | 0.7 | isoniazid | Not assoc w R - Interim |
ahpC | 2726669 | p.Asp159Glu | missense_variant | 0.56 | isoniazid | |
ahpC | 2726672 | c.480G>A | synonymous_variant | 0.58 | isoniazid | Not assoc w R - Interim |
ahpC | 2726675 | c.483A>G | synonymous_variant | 0.54 | isoniazid | |
ahpC | 2726681 | c.489A>C | synonymous_variant | 0.48 | isoniazid | Not assoc w R - Interim |
ahpC | 2726687 | c.495C>G | synonymous_variant | 0.45 | isoniazid | |
ahpC | 2726693 | c.501C>G | synonymous_variant | 0.43 | isoniazid | |
ahpC | 2726696 | c.504C>G | synonymous_variant | 0.42 | isoniazid | |
folC | 2747275 | c.324T>C | synonymous_variant | 0.6 | para-aminosalicylic_acid | |
folC | 2747302 | c.297A>G | synonymous_variant | 0.67 | para-aminosalicylic_acid | |
Rv2477c | 2782441 | c.1602G>A | synonymous_variant | 0.58 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782450 | c.1593C>A | synonymous_variant | 0.62 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782453 | c.1590C>G | synonymous_variant | 0.64 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782483 | c.1560G>C | synonymous_variant | 0.68 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782513 | c.1530G>T | synonymous_variant | 0.67 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782522 | c.1521G>C | synonymous_variant | 0.65 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782528 | c.1515G>C | synonymous_variant | 0.59 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782537 | c.1506T>G | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782540 | c.1503T>C | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782546 | c.1497C>G | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782549 | c.1494T>C | synonymous_variant | 0.4 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2782966 | c.1077C>A | synonymous_variant | 0.53 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 0.53 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782972 | c.1071G>C | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 0.52 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 0.35 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.46 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.54 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.47 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.47 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783098 | c.945C>G | synonymous_variant | 0.47 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783101 | c.942G>T | synonymous_variant | 0.47 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783107 | c.936G>A | synonymous_variant | 0.55 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.55 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783140 | c.903C>G | synonymous_variant | 0.56 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783149 | c.894G>C | synonymous_variant | 0.59 | ethambutol | |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783158 | c.885A>C | synonymous_variant | 0.57 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783182 | c.861C>G | synonymous_variant | 0.62 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783185 | c.858G>A | synonymous_variant | 0.68 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.71 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783221 | c.822G>C | synonymous_variant | 0.78 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783224 | c.819C>G | synonymous_variant | 0.82 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783230 | c.813T>G | synonymous_variant | 0.85 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783235 | c.808T>C | synonymous_variant | 0.89 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783254 | c.789A>G | synonymous_variant | 0.71 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783263 | c.780G>C | synonymous_variant | 0.67 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783275 | c.768C>G | synonymous_variant | 0.53 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783278 | c.765A>G | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783620 | c.423C>G | synonymous_variant | 0.53 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.56 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.6 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.64 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.61 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.64 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.57 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783718 | c.325T>C | synonymous_variant | 0.57 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 0.57 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.44 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783766 | p.Met93Leu | missense_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783776 | c.267G>C | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783779 | c.264T>C | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783929 | c.114C>G | synonymous_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783932 | c.111C>T | synonymous_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783938 | c.105T>C | synonymous_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783953 | c.90G>A | synonymous_variant | 0.3 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783962 | c.81T>C | synonymous_variant | 0.33 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | ||||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783971 | c.72G>C | synonymous_variant | 0.34 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783980 | c.63C>G | synonymous_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783992 | c.51T>C | synonymous_variant | 0.38 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2784396 | c.-354A>C | upstream_gene_variant | 0.36 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784405 | c.-363T>C | upstream_gene_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784428 | c.-386T>C | upstream_gene_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784429 | c.-387A>G | upstream_gene_variant | 0.36 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784432 | c.-390A>C | upstream_gene_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784435 | c.-393C>G | upstream_gene_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784452 | c.-410C>T | upstream_gene_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784454 | c.-412G>A | upstream_gene_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784456 | c.-414A>C | upstream_gene_variant | 0.36 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784472 | c.-430C>A | upstream_gene_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784477 | c.-435T>C | upstream_gene_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2752c | 3065988 | c.204A>G | synonymous_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065993 | p.Val67Ile | missense_variant | 0.4 | ethambutol | Uncertain significance |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv2752c | 3066018 | c.174T>C | synonymous_variant | 0.43 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066024 | c.168T>G | synonymous_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066118 | p.Asn25Ser | missense_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066261 | c.-70G>C | upstream_gene_variant | 0.37 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066270 | c.-79G>A | upstream_gene_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066276 | c.-85G>A | upstream_gene_variant | 0.37 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066279 | c.-88A>G | upstream_gene_variant | 0.37 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066282 | c.-91G>T | upstream_gene_variant | 0.37 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066287 | c.-96G>C | upstream_gene_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066290 | c.-99G>A | upstream_gene_variant | 0.37 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066291 | c.-100G>A | upstream_gene_variant | 0.37 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066309 | c.-118T>C | upstream_gene_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066330 | c.-139G>C | upstream_gene_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066807 | c.-616T>C | upstream_gene_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066810 | c.-619G>A | upstream_gene_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
thyX | 3067349 | c.597G>C | synonymous_variant | 0.56 | para-aminosalicylic_acid | |
thyX | 3067355 | c.591A>C | synonymous_variant | 0.56 | para-aminosalicylic_acid | |
thyX | 3067367 | c.579G>C | synonymous_variant | 0.58 | para-aminosalicylic_acid | |
thyX | 3067373 | c.573C>G | synonymous_variant | 0.61 | para-aminosalicylic_acid | |
thyX | 3067391 | c.555G>C | synonymous_variant | 0.67 | para-aminosalicylic_acid | |
thyX | 3067394 | c.552G>C | synonymous_variant | 0.74 | para-aminosalicylic_acid | |
thyX | 3067439 | c.507A>G | synonymous_variant | 0.76 | para-aminosalicylic_acid | |
thyX | 3067442 | c.504C>T | synonymous_variant | 0.72 | para-aminosalicylic_acid | |
thyX | 3067445 | c.501C>G | synonymous_variant | 0.76 | para-aminosalicylic_acid | |
thyX | 3067457 | c.489C>G | synonymous_variant | 0.8 | para-aminosalicylic_acid | |
thyX | 3067462 | c.484C>T | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
thyX | 3067465 | p.Ile161Val | missense_variant | 0.73 | para-aminosalicylic_acid | |
thyX | 3067466 | c.480G>C | synonymous_variant | 0.73 | para-aminosalicylic_acid | |
thyX | 3067475 | c.471A>G | synonymous_variant | 0.73 | para-aminosalicylic_acid | |
thyX | 3067490 | c.456C>G | synonymous_variant | 0.62 | para-aminosalicylic_acid | |
thyX | 3067493 | c.453A>G | synonymous_variant | 0.58 | para-aminosalicylic_acid | |
thyX | 3067510 | c.436C>T | synonymous_variant | 0.54 | para-aminosalicylic_acid | |
thyX | 3067515 | p.Ser144Thr | missense_variant | 0.58 | para-aminosalicylic_acid | |
thyX | 3067530 | p.Ala139Ser | missense_variant | 0.58 | para-aminosalicylic_acid | |
thyX | 3067545 | p.Glu134Ala | missense_variant | 0.75 | para-aminosalicylic_acid | |
thyX | 3067549 | p.Thr133Ala | missense_variant | 0.64 | para-aminosalicylic_acid | |
thyX | 3067556 | p.His130Gln | missense_variant | 0.67 | para-aminosalicylic_acid | |
thyX | 3067559 | c.387C>G | synonymous_variant | 0.67 | para-aminosalicylic_acid | |
thyX | 3067565 | p.Asp127Glu | missense_variant | 0.69 | para-aminosalicylic_acid | |
thyX | 3067570 | p.Ala126Pro | missense_variant | 0.69 | para-aminosalicylic_acid | |
thyX | 3067577 | c.369G>A | synonymous_variant | 0.71 | para-aminosalicylic_acid | |
thyX | 3067601 | p.Arg115His | missense_variant | 0.77 | para-aminosalicylic_acid | |
thyX | 3067611 | p.Lys112Thr | missense_variant | 0.69 | para-aminosalicylic_acid | |
thyX | 3067619 | c.327A>C | synonymous_variant | 0.67 | para-aminosalicylic_acid | |
thyX | 3067661 | c.285C>G | synonymous_variant | 0.65 | para-aminosalicylic_acid | |
thyX | 3067685 | c.261A>C | synonymous_variant | 0.62 | para-aminosalicylic_acid | |
thyX | 3067691 | c.253_255delATCinsCG | frameshift_variant&missense_variant | 0.59 | para-aminosalicylic_acid | |
thyX | 3067694 | c.252G>C | synonymous_variant | 0.59 | para-aminosalicylic_acid | |
thyX | 3067718 | c.228C>G | synonymous_variant | 0.69 | para-aminosalicylic_acid | |
thyX | 3067721 | c.225T>C | synonymous_variant | 0.72 | para-aminosalicylic_acid | |
thyX | 3067727 | c.219A>C | synonymous_variant | 0.84 | para-aminosalicylic_acid | |
thyX | 3067736 | c.210C>T | synonymous_variant | 0.88 | para-aminosalicylic_acid | |
thyX | 3067761 | p.Arg62Lys | missense_variant | 0.79 | para-aminosalicylic_acid | |
thyX | 3067765 | p.Leu61Ile | missense_variant | 0.79 | para-aminosalicylic_acid | |
thyX | 3067772 | c.174C>G | synonymous_variant | 0.79 | para-aminosalicylic_acid | |
thyX | 3067775 | c.171C>T | synonymous_variant | 0.8 | para-aminosalicylic_acid | |
thyX | 3067781 | c.165C>G | synonymous_variant | 0.8 | para-aminosalicylic_acid | |
thyX | 3067793 | c.153T>C | synonymous_variant | 0.76 | para-aminosalicylic_acid | |
thyX | 3067799 | c.147G>A | synonymous_variant | 0.75 | para-aminosalicylic_acid | |
thyX | 3067802 | c.144C>G | synonymous_variant | 0.67 | para-aminosalicylic_acid | |
thyX | 3067814 | c.132T>C | synonymous_variant | 0.58 | para-aminosalicylic_acid | |
thyX | 3067850 | c.96A>C | synonymous_variant | 0.44 | para-aminosalicylic_acid | |
thyX | 3067869 | p.Thr26Ser | missense_variant | 0.47 | para-aminosalicylic_acid | |
thyX | 3067874 | c.72C>G | synonymous_variant | 0.5 | para-aminosalicylic_acid | |
thyX | 3067877 | c.69G>C | synonymous_variant | 0.47 | para-aminosalicylic_acid | |
thyX | 3067883 | c.63C>G | synonymous_variant | 0.44 | para-aminosalicylic_acid | |
thyX | 3067886 | c.60A>C | synonymous_variant | 0.44 | para-aminosalicylic_acid | |
thyX | 3067889 | c.57C>G | synonymous_variant | 0.47 | para-aminosalicylic_acid | |
thyX | 3067894 | c.52T>C | synonymous_variant | 0.47 | para-aminosalicylic_acid | |
thyX | 3067898 | p.Asp16Glu | missense_variant | 0.47 | para-aminosalicylic_acid | |
thyA | 3073892 | c.580T>C | synonymous_variant | 0.77 | para-aminosalicylic_acid | |
thyA | 3074205 | p.Glu89Asp | missense_variant | 0.44 | para-aminosalicylic_acid | |
Rv3083 | 3448507 | c.5_*1408del | frameshift_variant&stop_lost&splice_region_variant | 1.0 | ethionamide | Uncertain significance |
lpqB | 3623512 | p.Gly467Ser | missense_variant | 0.46 | bedaquiline | |
rifampicin | ||||||
lpqB | 3623531 | c.1380T>C | synonymous_variant | 0.35 | bedaquiline | |
rifampicin | ||||||
lpqB | 3623549 | c.1362C>G | synonymous_variant | 0.44 | bedaquiline | |
rifampicin | ||||||
lpqB | 3623555 | c.1354_1356delGGGinsAC | frameshift_variant&missense_variant | 0.44 | bedaquiline | |
rifampicin | Uncertain significance | |||||
lpqB | 3623561 | c.1350T>C | synonymous_variant | 0.47 | bedaquiline | |
rifampicin | ||||||
lpqB | 3623570 | c.1341A>G | synonymous_variant | 0.43 | bedaquiline | |
rifampicin | ||||||
lpqB | 3623573 | c.1338T>G | synonymous_variant | 0.4 | bedaquiline | |
rifampicin | ||||||
lpqB | 3623576 | c.1335T>C | synonymous_variant | 0.4 | bedaquiline | |
rifampicin | ||||||
lpqB | 3623580 | p.Asn444Thr | missense_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625569 | c.1045T>C | synonymous_variant | 0.5 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625572 | p.Thr348Ser | missense_variant | 0.47 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 0.53 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 0.47 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.47 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 0.47 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625616 | p.Arg333Ala | missense_variant | 0.44 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 0.44 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625636 | c.978C>G | synonymous_variant | 0.54 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625705 | c.909C>G | synonymous_variant | 0.58 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625711 | c.903C>T | synonymous_variant | 0.57 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 0.56 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625720 | c.894G>C | synonymous_variant | 0.65 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625729 | c.885A>G | synonymous_variant | 0.6 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 0.58 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625749 | c.-839C>T | upstream_gene_variant | 0.58 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.63 | bedaquiline | |
rifampicin | Uncertain significance | |||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 0.65 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625774 | c.840G>A | synonymous_variant | 0.65 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625797 | p.Val273Met | missense_variant | 0.71 | bedaquiline | Uncertain significance |
rifampicin | Uncertain significance | |||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.62 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625807 | c.807C>G | synonymous_variant | 0.59 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625837 | c.777C>G | synonymous_variant | 0.62 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 0.58 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625852 | c.762A>G | synonymous_variant | 0.55 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 0.53 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626687 | c.-74G>T | upstream_gene_variant | 0.4 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626704 | c.-91C>T | upstream_gene_variant | 0.58 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626711 | c.-98T>C | upstream_gene_variant | 0.62 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626723 | c.627C>T | synonymous_variant | 0.69 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 0.69 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 0.69 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 0.69 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 0.9 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3626774 | c.574_576delAGGinsCC | frameshift_variant&missense_variant | 0.88 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 0.93 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626786 | c.564A>G | synonymous_variant | 0.87 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3626792 | c.558G>T | synonymous_variant | 0.87 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 0.86 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 0.88 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.88 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 0.82 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 0.87 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 0.8 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 0.8 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 0.8 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626869 | c.481C>T | synonymous_variant | 0.8 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 0.82 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626885 | c.-272A>C | upstream_gene_variant | 0.82 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 0.69 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 0.54 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626969 | c.381C>T | synonymous_variant | 0.54 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 0.54 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 0.67 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.67 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 0.54 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627119 | c.231T>G | synonymous_variant | 0.6 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.6 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627146 | c.204C>T | synonymous_variant | 0.73 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 0.65 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 0.62 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 0.6 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627188 | c.162A>G | synonymous_variant | 0.59 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 0.65 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627221 | c.129C>T | synonymous_variant | 0.67 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3627227 | c.123T>C | synonymous_variant | 0.68 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 0.65 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.65 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627242 | c.108C>T | synonymous_variant | 0.62 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.55 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 0.6 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 0.6 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 0.59 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627275 | c.-662G>T | upstream_gene_variant | 0.59 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 0.58 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627299 | c.49_51delTTGinsCA | frameshift_variant&missense_variant | 0.58 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627314 | c.-701C>T | upstream_gene_variant | 0.63 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 0.62 | bedaquiline | |
rifampicin | ||||||
rpoA | 3877503 | c.1005G>C | synonymous_variant | 0.54 | rifampicin | |
rpoA | 3877507 | p.Gly334Ala | missense_variant | 0.6 | rifampicin | |
rpoA | 3877515 | c.993G>C | synonymous_variant | 0.58 | rifampicin | |
rpoA | 3877553 | p.Glu319Gln | missense_variant | 0.67 | rifampicin | |
rpoA | 3877571 | p.Pro313Ala | missense_variant | 0.71 | rifampicin | |
rpoA | 3877587 | c.921A>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.65 | rifampicin | |
rpoA | 3877656 | c.852T>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoA | 3877668 | c.840A>G | synonymous_variant | 0.45 | rifampicin | |
rpoA | 3877679 | p.Ala277Ser | missense_variant | 0.44 | rifampicin | |
rpoA | 3877686 | c.822A>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>C | synonymous_variant | 0.48 | rifampicin | |
rpoA | 3877737 | c.771G>C | synonymous_variant | 0.48 | rifampicin | |
rpoA | 3877743 | c.765T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoA | 3877791 | c.717C>G | synonymous_variant | 0.57 | rifampicin | |
rpoA | 3877818 | c.690A>G | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoA | 3877848 | c.660C>T | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoA | 3877857 | c.651G>A | synonymous_variant | 0.5 | rifampicin | |
rpoA | 3877866 | c.642G>C | synonymous_variant | 0.5 | rifampicin | |
rpoA | 3877875 | c.633T>G | synonymous_variant | 0.48 | rifampicin | |
rpoA | 3877878 | c.630G>C | synonymous_variant | 0.5 | rifampicin | |
rpoA | 3877920 | c.588G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoA | 3877923 | c.585C>T | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoA | 3877926 | c.582G>C | synonymous_variant | 0.53 | rifampicin | |
rpoA | 3878001 | c.507A>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoA | 3878022 | c.486T>C | synonymous_variant | 0.54 | rifampicin | |
rpoA | 3878028 | c.480G>C | synonymous_variant | 0.52 | rifampicin | |
rpoA | 3878031 | c.477T>C | synonymous_variant | 0.54 | rifampicin | |
rpoA | 3878040 | c.468T>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoA | 3878055 | c.453A>G | synonymous_variant | 0.45 | rifampicin | |
rpoA | 3878058 | c.450G>T | synonymous_variant | 0.45 | rifampicin | |
rpoA | 3878061 | c.447G>C | synonymous_variant | 0.42 | rifampicin | |
rpoA | 3878067 | c.441C>G | synonymous_variant | 0.44 | rifampicin | |
rpoA | 3878070 | c.438T>C | synonymous_variant | 0.44 | rifampicin | |
rpoA | 3878076 | c.432C>T | synonymous_variant | 0.5 | rifampicin | |
rpoA | 3878157 | c.351C>G | synonymous_variant | 0.64 | rifampicin | |
rpoA | 3878163 | c.345C>T | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoA | 3878169 | c.339G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoA | 3878172 | c.336G>C | synonymous_variant | 0.56 | rifampicin | |
rpoA | 3878187 | c.321C>G | synonymous_variant | 0.48 | rifampicin | |
rpoA | 3878193 | c.315T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoA | 3878199 | c.309T>C | synonymous_variant | 0.46 | rifampicin | |
rpoA | 3878217 | c.291A>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoA | 3878226 | c.282C>G | synonymous_variant | 0.48 | rifampicin | |
rpoA | 3878232 | c.276G>C | synonymous_variant | 0.48 | rifampicin | |
rpoA | 3878247 | c.261G>C | synonymous_variant | 0.56 | rifampicin | |
rpoA | 3878271 | c.237T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoA | 3878284 | p.Glu75Ala | missense_variant | 0.67 | rifampicin | |
rpoA | 3878292 | c.216T>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoA | 3878298 | c.210A>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoA | 3878304 | c.204G>C | synonymous_variant | 0.53 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoA | 3878322 | c.186A>G | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoA | 3878331 | c.177A>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoA | 3878334 | c.174T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R - Interim |
rpoA | 3878346 | c.162T>C | synonymous_variant | 0.64 | rifampicin | |
rpoA | 3878364 | c.144A>T | synonymous_variant | 0.53 | rifampicin | |
rpoA | 3878367 | c.141C>G | synonymous_variant | 0.55 | rifampicin | |
rpoA | 3878376 | c.132G>C | synonymous_variant | 0.64 | rifampicin | |
rpoA | 3878385 | c.123C>G | synonymous_variant | 0.71 | rifampicin | |
rpoA | 3878388 | c.120C>G | synonymous_variant | 0.75 | rifampicin | |
rpoA | 3878391 | c.117T>C | synonymous_variant | 0.73 | rifampicin | |
rpoA | 3878415 | c.93C>T | synonymous_variant | 0.73 | rifampicin | |
rpoA | 3878424 | c.84G>C | synonymous_variant | 0.75 | rifampicin | |
rpoA | 3878436 | c.72A>G | synonymous_variant | 0.71 | rifampicin | |
rpoA | 3878442 | c.66G>C | synonymous_variant | 0.64 | rifampicin | |
rpoA | 3878454 | c.54A>C | synonymous_variant | 0.64 | rifampicin | |
rpoA | 3878472 | p.Asp12Glu | missense_variant | 0.53 | rifampicin | |
rpoA | 3878478 | c.30C>G | synonymous_variant | 0.5 | rifampicin | |
rpoA | 3878484 | c.24C>A | synonymous_variant | 0.47 | rifampicin | |
rpoA | 3878761 | c.-254G>C | upstream_gene_variant | 0.86 | rifampicin | |
rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 0.8 | rifampicin | |
rpoA | 3878785 | c.-278T>G | upstream_gene_variant | 0.71 | rifampicin | |
rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.67 | rifampicin | Uncertain significance |
rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 0.72 | rifampicin | |
rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.72 | rifampicin | |
rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 0.64 | rifampicin | |
rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.57 | rifampicin | |
rpoA | 3878836 | c.-331_-329delAAGinsTCC | upstream_gene_variant | 0.5 | rifampicin | |
rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.48 | rifampicin | |
rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.59 | rifampicin | Uncertain significance |
rpoA | 3878917 | c.-410G>A | upstream_gene_variant | 0.53 | rifampicin | Uncertain significance |
rpoA | 3878938 | c.-431T>C | upstream_gene_variant | 0.71 | rifampicin | |
rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 0.67 | rifampicin | Uncertain significance |
rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 0.73 | rifampicin | Uncertain significance |
rpoA | 3878976 | c.-469A>G | upstream_gene_variant | 0.75 | rifampicin | Uncertain significance |
rpoA | 3878986 | c.-479G>C | upstream_gene_variant | 0.71 | rifampicin | |
rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 0.68 | rifampicin | Uncertain significance |
rpoA | 3879005 | c.-499_-498delAAinsCG | upstream_gene_variant | 0.68 | rifampicin | |
rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 0.73 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.7 | rifampicin | |
rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.63 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.67 | rifampicin | |
rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.7 | rifampicin | |
rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.78 | rifampicin | |
rpoA | 3879178 | c.-671T>C | upstream_gene_variant | 0.75 | rifampicin | |
rpoA | 3879190 | c.-683C>G | upstream_gene_variant | 0.5 | rifampicin | |
clpC1 | 4038509 | c.2196C>T | synonymous_variant | 0.79 | pyrazinamide | |
clpC1 | 4038530 | p.Glu725Asp | missense_variant | 0.61 | pyrazinamide | |
clpC1 | 4038541 | c.2164C>T | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4038683 | c.2022T>C | synonymous_variant | 0.5 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038695 | c.2010C>G | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4038707 | c.1998C>G | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4038710 | c.1995G>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4038749 | c.1956C>G | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4038755 | c.1950G>T | synonymous_variant | 0.85 | pyrazinamide | |
clpC1 | 4038770 | c.1935C>T | synonymous_variant | 0.79 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.79 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.81 | pyrazinamide | |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.73 | pyrazinamide | |
clpC1 | 4038845 | c.1860G>C | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4038923 | c.1780_1782delCTAinsTG | frameshift_variant&synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.79 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.73 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.81 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.81 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.82 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.88 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039004 | c.1701C>G | synonymous_variant | 0.88 | pyrazinamide | |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.86 | pyrazinamide | |
clpC1 | 4039064 | c.1641C>T | synonymous_variant | 0.75 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.72 | pyrazinamide | |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.72 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.65 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.65 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.67 | pyrazinamide | |
clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4039186 | c.1519C>T | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.81 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039229 | c.1476C>G | synonymous_variant | 0.81 | pyrazinamide | |
clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.67 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.7 | pyrazinamide | |
clpC1 | 4039295 | c.1410A>C | synonymous_variant | 0.63 | pyrazinamide | |
clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.63 | pyrazinamide | |
clpC1 | 4039364 | c.1341C>G | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4039556 | c.1149G>C | synonymous_variant | 0.58 | pyrazinamide | |
clpC1 | 4039559 | c.1146C>G | synonymous_variant | 0.55 | pyrazinamide | |
clpC1 | 4039562 | c.1143C>G | synonymous_variant | 0.6 | pyrazinamide | |
clpC1 | 4039565 | c.1140G>T | synonymous_variant | 0.6 | pyrazinamide | |
clpC1 | 4039570 | p.Met379Leu | missense_variant | 0.6 | pyrazinamide | Uncertain significance |
clpC1 | 4039576 | p.Ala377Pro | missense_variant | 0.62 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.62 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039589 | c.1116G>C | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.65 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.65 | pyrazinamide | |
clpC1 | 4039661 | c.1044T>G | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4039664 | c.1041G>C | synonymous_variant | 0.66 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4039757 | c.948A>G | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4039760 | c.945T>C | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039775 | c.930G>C | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039781 | c.924G>C | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4039790 | c.915C>G | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4039817 | c.888A>C | synonymous_variant | 0.6 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039820 | c.885T>G | synonymous_variant | 0.59 | pyrazinamide | |
clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.63 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.83 | pyrazinamide | |
clpC1 | 4039946 | c.759A>C | synonymous_variant | 0.55 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4039979 | c.726C>G | synonymous_variant | 0.6 | pyrazinamide | |
clpC1 | 4039988 | c.717C>G | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.61 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4040036 | c.669C>G | synonymous_variant | 0.65 | pyrazinamide | |
clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4040093 | c.612C>G | synonymous_variant | 0.53 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.61 | pyrazinamide | |
clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.67 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040162 | c.543G>C | synonymous_variant | 0.6 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040165 | c.540G>C | synonymous_variant | 0.58 | pyrazinamide | |
clpC1 | 4040171 | c.534C>G | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4040201 | c.504C>G | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4040207 | c.498T>G | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4040225 | c.480A>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4040228 | c.477G>T | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4040231 | c.474C>T | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4040237 | c.468C>T | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4040246 | c.459C>G | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4040249 | c.456A>G | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4040477 | c.228G>C | synonymous_variant | 0.55 | pyrazinamide | |
clpC1 | 4040480 | c.225T>G | synonymous_variant | 0.5 | pyrazinamide | |
panD | 4043865 | c.415_417delGGAinsCG | frameshift_variant&missense_variant | 0.4 | pyrazinamide | Uncertain significance |
panD | 4043872 | p.Gly137Val | missense_variant | 0.4 | pyrazinamide | Uncertain significance |
panD | 4043876 | p.Leu136Ile | missense_variant | 0.42 | pyrazinamide | |
panD | 4043883 | c.399C>T | synonymous_variant | 0.47 | pyrazinamide | |
panD | 4043886 | c.396A>G | synonymous_variant | 0.47 | pyrazinamide | |
panD | 4043896 | p.Gly129Ala | missense_variant | 0.47 | pyrazinamide | |
panD | 4043903 | p.Asn127Asp | missense_variant | 0.44 | pyrazinamide | |
panD | 4043913 | c.369T>C | synonymous_variant | 0.35 | pyrazinamide | |
panD | 4043916 | c.366A>G | synonymous_variant | 0.38 | pyrazinamide | |
panD | 4044779 | c.-500_-498delCTAinsTGC | upstream_gene_variant | 0.33 | pyrazinamide | |
panD | 4044788 | c.-507G>C | upstream_gene_variant | 0.38 | pyrazinamide | |
panD | 4044791 | c.-510G>C | upstream_gene_variant | 0.38 | pyrazinamide | |
panD | 4044800 | c.-519C>G | upstream_gene_variant | 0.41 | pyrazinamide | |
panD | 4044812 | c.-531A>C | upstream_gene_variant | 0.41 | pyrazinamide | |
panD | 4045055 | c.-774T>G | upstream_gene_variant | 0.5 | pyrazinamide | |
glpK | 4138670 | c.1086G>C | synonymous_variant | 0.64 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138679 | c.1075_1077delATGinsGC | frameshift_variant&missense_variant | 0.77 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
glpK | 4138695 | p.Pro354Asp | missense_variant | 0.85 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138718 | c.1038T>C | synonymous_variant | 0.8 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138721 | c.1035G>A | synonymous_variant | 0.79 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4138724 | c.1032A>G | synonymous_variant | 0.79 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138730 | c.1026C>G | synonymous_variant | 0.73 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138757 | c.999A>G | synonymous_variant | 0.67 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138763 | c.993G>A | synonymous_variant | 0.59 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138769 | c.987G>C | synonymous_variant | 0.53 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138774 | p.Ser328Ala | missense_variant | 0.43 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138778 | c.978C>G | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
embC | 4239336 | c.-527T>C | upstream_gene_variant | 0.46 | ethambutol | |
embC | 4239341 | c.-522G>C | upstream_gene_variant | 0.55 | ethambutol | |
embC | 4239344 | c.-519G>C | upstream_gene_variant | 0.55 | ethambutol | |
embC | 4239350 | c.-513G>C | upstream_gene_variant | 0.6 | ethambutol | |
embC | 4240178 | c.316T>C | synonymous_variant | 0.67 | ethambutol | |
embC | 4240183 | c.321A>G | synonymous_variant | 0.67 | ethambutol | |
embC | 4240204 | c.342T>C | synonymous_variant | 0.69 | ethambutol | Not assoc w R - Interim |
embC | 4240216 | c.354T>C | synonymous_variant | 0.64 | ethambutol | |
embC | 4240219 | c.357C>G | synonymous_variant | 0.64 | ethambutol | |
embC | 4240222 | c.360G>C | synonymous_variant | 0.64 | ethambutol | |
embC | 4240229 | c.367_369delCTGinsAC | frameshift_variant&missense_variant | 0.69 | ethambutol | |
embC | 4240232 | p.Gln124Val | missense_variant | 0.69 | ethambutol | |
embC | 4240249 | p.Asp129Glu | missense_variant | 0.56 | ethambutol | |
embC | 4240258 | c.396T>G | synonymous_variant | 0.56 | ethambutol | |
embC | 4240726 | c.864G>C | synonymous_variant | 0.6 | ethambutol | Not assoc w R - Interim |
embC | 4240780 | c.918T>C | synonymous_variant | 0.64 | ethambutol | |
embC | 4240783 | c.921G>C | synonymous_variant | 0.64 | ethambutol | |
embC | 4240789 | c.927T>C | synonymous_variant | 0.67 | ethambutol | |
embC | 4240867 | c.1005T>C | synonymous_variant | 0.56 | ethambutol | |
embC | 4240870 | c.1008T>C | synonymous_variant | 0.56 | ethambutol | |
embC | 4240873 | c.1011C>G | synonymous_variant | 0.53 | ethambutol | |
embC | 4240879 | c.1017G>C | synonymous_variant | 0.53 | ethambutol | |
embC | 4240880 | p.Ala340Thr | missense_variant | 0.53 | ethambutol | Uncertain significance |
embC | 4240885 | c.1023T>C | synonymous_variant | 0.53 | ethambutol | |
embC | 4240897 | c.1035C>G | synonymous_variant | 0.53 | ethambutol | Not assoc w R |
embC | 4240898 | c.1036_1038delCTAinsTG | frameshift_variant&stop_gained | 0.53 | ethambutol | |
embC | 4240903 | c.1041C>G | synonymous_variant | 0.53 | ethambutol | |
embC | 4240911 | p.Ala350Val | missense_variant | 0.57 | ethambutol | |
embC | 4240921 | c.1059C>G | synonymous_variant | 0.62 | ethambutol | |
embC | 4240924 | c.1062C>G | synonymous_variant | 0.73 | ethambutol | |
embC | 4240936 | c.1074A>G | synonymous_variant | 0.58 | ethambutol | |
embC | 4241089 | c.1227C>G | synonymous_variant | 0.6 | ethambutol | |
embC | 4241095 | c.1233C>T | synonymous_variant | 0.58 | ethambutol | |
embC | 4241107 | c.1245G>C | synonymous_variant | 0.73 | ethambutol | |
embC | 4241140 | c.1278A>G | synonymous_variant | 0.83 | ethambutol | Not assoc w R - Interim |
embC | 4241146 | c.1284C>G | synonymous_variant | 0.88 | ethambutol | |
embC | 4241158 | c.1296T>C | synonymous_variant | 0.86 | ethambutol | |
embC | 4241161 | c.1299C>G | synonymous_variant | 0.85 | ethambutol | Not assoc w R - Interim |
embC | 4241162 | c.1300T>C | synonymous_variant | 0.85 | ethambutol | |
embC | 4241170 | c.1308G>C | synonymous_variant | 0.77 | ethambutol | |
embC | 4241173 | c.1311C>T | synonymous_variant | 0.77 | ethambutol | |
embC | 4241203 | c.1341T>C | synonymous_variant | 0.54 | ethambutol | |
embC | 4241206 | c.1344G>C | synonymous_variant | 0.54 | ethambutol | Not assoc w R - Interim |
embC | 4241218 | c.1356G>C | synonymous_variant | 0.54 | ethambutol | |
embC | 4241479 | c.1617C>G | synonymous_variant | 0.54 | ethambutol | |
embC | 4241480 | c.1618T>C | synonymous_variant | 0.54 | ethambutol | |
embC | 4241488 | c.1626G>C | synonymous_variant | 0.5 | ethambutol | |
embC | 4241496 | p.Ala545Gly | missense_variant | 0.43 | ethambutol | |
embC | 4241500 | c.1638A>C | synonymous_variant | 0.43 | ethambutol | |
embC | 4241501 | p.Ser547Thr | missense_variant | 0.43 | ethambutol | |
embC | 4241506 | c.1644G>C | synonymous_variant | 0.43 | ethambutol | |
embC | 4241518 | c.1656A>G | synonymous_variant | 0.43 | ethambutol | |
embC | 4241521 | c.1659T>C | synonymous_variant | 0.5 | ethambutol | Not assoc w R - Interim |
embC | 4241530 | c.1668C>G | synonymous_variant | 0.53 | ethambutol | |
embC | 4242764 | p.Val968Leu | missense_variant | 0.47 | ethambutol | |
embA | 4242772 | c.-461G>C | upstream_gene_variant | 0.53 | ethambutol | |
embC | 4242779 | p.Asn973Asp | missense_variant | 0.53 | ethambutol | |
embA | 4244507 | c.1275G>T | synonymous_variant | 0.5 | ethambutol | Not assoc w R - Interim |
embA | 4244508 | c.1276T>C | synonymous_variant | 0.5 | ethambutol | |
embA | 4244516 | c.1284G>C | synonymous_variant | 0.53 | ethambutol | |
embA | 4244517 | p.Leu429Val | missense_variant | 0.5 | ethambutol | |
embA | 4244523 | p.Pro431Ala | missense_variant | 0.5 | ethambutol | |
embA | 4244534 | c.1302T>C | synonymous_variant | 0.5 | ethambutol | |
embA | 4244537 | c.1305T>G | synonymous_variant | 0.53 | ethambutol | |
embA | 4244543 | c.1311C>G | synonymous_variant | 0.53 | ethambutol | |
embA | 4244547 | p.Ile439Val | missense_variant | 0.6 | ethambutol | |
embA | 4245101 | c.1869G>C | synonymous_variant | 0.55 | ethambutol | |
embA | 4245137 | c.1905T>C | synonymous_variant | 0.6 | ethambutol | |
embA | 4245146 | c.1914G>A | synonymous_variant | 0.6 | ethambutol | |
embA | 4245149 | c.1917C>G | synonymous_variant | 0.63 | ethambutol | |
embA | 4245153 | p.Ile641Val | missense_variant | 0.67 | ethambutol | |
embA | 4245182 | c.1950T>C | synonymous_variant | 0.72 | ethambutol | |
embA | 4245189 | c.1957C>T | synonymous_variant | 0.68 | ethambutol | |
embA | 4245198 | p.Leu656Ile | missense_variant | 0.58 | ethambutol | |
embA | 4245207 | c.1975T>C | synonymous_variant | 0.5 | ethambutol | |
embB | 4245725 | c.-789A>G | upstream_gene_variant | 0.6 | ethambutol | |
embB | 4245726 | c.-788T>C | upstream_gene_variant | 0.6 | ethambutol | |
embB | 4245737 | c.-777A>C | upstream_gene_variant | 0.64 | ethambutol | |
embB | 4245740 | c.-774T>C | upstream_gene_variant | 0.75 | ethambutol | |
embA | 4246080 | c.2848_2850delCCTinsTC | frameshift_variant&missense_variant | 0.47 | ethambutol | Uncertain significance |
embA | 4246088 | c.2856A>G | synonymous_variant | 0.56 | ethambutol | Not assoc w R |
embB | 4246097 | c.-417C>G | upstream_gene_variant | 0.53 | ethambutol | |
embA | 4246103 | c.2871C>G | synonymous_variant | 0.47 | ethambutol | Not assoc w R - Interim |
embB | 4246109 | c.-405C>G | upstream_gene_variant | 0.37 | ethambutol | |
embA | 4246264 | p.His1011Arg | missense_variant | 0.44 | ethambutol | |
embB | 4246292 | c.-222A>G | upstream_gene_variant | 0.44 | ethambutol | |
embA | 4246305 | p.Ser1025Glu | missense_variant | 0.44 | ethambutol | |
embA | 4246308 | p.Thr1026Ala | missense_variant | 0.44 | ethambutol | |
embB | 4246316 | c.-198T>G | upstream_gene_variant | 0.48 | ethambutol | |
embB | 4246319 | c.-195G>C | upstream_gene_variant | 0.53 | ethambutol | |
embA | 4246329 | p.Thr1033Ala | missense_variant | 0.6 | ethambutol | |
embB | 4246349 | c.-165C>G | upstream_gene_variant | 0.72 | ethambutol | |
embA | 4246359 | c.3127_3129delGCCinsTG | frameshift_variant&missense_variant | 0.71 | ethambutol | Uncertain significance |
embB | 4246367 | c.-147C>T | upstream_gene_variant | 0.62 | ethambutol | |
embB | 4246373 | c.-141T>C | upstream_gene_variant | 0.67 | ethambutol | |
embB | 4246376 | c.-138G>C | upstream_gene_variant | 0.67 | ethambutol | |
embA | 4246379 | c.3147C>T | synonymous_variant | 0.67 | ethambutol | Not assoc w R - Interim |
embB | 4247446 | c.933C>T | synonymous_variant | 0.57 | ethambutol | |
embB | 4247464 | c.951C>G | synonymous_variant | 0.71 | ethambutol | |
embB | 4247470 | c.957T>C | synonymous_variant | 0.73 | ethambutol | |
embB | 4247491 | c.978G>C | synonymous_variant | 0.74 | ethambutol | |
embB | 4247497 | c.984T>C | synonymous_variant | 0.71 | ethambutol | |
embB | 4247512 | c.999T>C | synonymous_variant | 0.7 | ethambutol | |
embB | 4247539 | c.1026T>C | synonymous_variant | 0.67 | ethambutol | |
embB | 4247554 | c.1041T>C | synonymous_variant | 0.5 | ethambutol | |
embB | 4247566 | c.1053C>A | synonymous_variant | 0.45 | ethambutol | |
embB | 4247572 | c.1059A>G | synonymous_variant | 0.45 | ethambutol | |
embB | 4247729 | p.Gly406Thr | missense_variant | 1.0 | ethambutol | |
embB | 4247761 | c.1248T>C | synonymous_variant | 0.6 | ethambutol | |
embB | 4247905 | c.1392G>C | synonymous_variant | 0.53 | ethambutol | Not assoc w R - Interim |
embB | 4247909 | c.1396T>C | synonymous_variant | 0.5 | ethambutol | |
embB | 4247914 | c.1401G>C | synonymous_variant | 0.5 | ethambutol | Not assoc w R - Interim |
embB | 4247932 | c.1419C>G | synonymous_variant | 0.5 | ethambutol | |
embB | 4247940 | p.Leu476Trp | missense_variant | 0.56 | ethambutol | |
embB | 4247945 | c.1432T>C | synonymous_variant | 0.47 | ethambutol | |
embB | 4247951 | p.Ser480Ala | missense_variant | 0.47 | ethambutol | |
embB | 4247956 | c.1443G>C | synonymous_variant | 0.47 | ethambutol | Not assoc w R - Interim |
embB | 4248035 | p.Val508Ile | missense_variant | 0.69 | ethambutol | |
embB | 4248040 | c.1527C>G | synonymous_variant | 0.69 | ethambutol | |
embB | 4248041 | p.Ala510Thr | missense_variant | 0.69 | ethambutol | Uncertain significance |
embB | 4248044 | p.Lys511Ala | missense_variant | 0.69 | ethambutol | |
embB | 4248070 | c.1557T>C | synonymous_variant | 0.71 | ethambutol | |
embB | 4248130 | c.1617G>C | synonymous_variant | 0.53 | ethambutol | |
embB | 4248142 | c.1629T>C | synonymous_variant | 0.53 | ethambutol | |
embB | 4248143 | c.1630T>C | synonymous_variant | 0.53 | ethambutol | |
embB | 4248157 | c.1644A>G | synonymous_variant | 0.5 | ethambutol | Not assoc w R - Interim |
embB | 4248172 | c.1659G>C | synonymous_variant | 0.53 | ethambutol | |
embB | 4248199 | c.1686A>G | synonymous_variant | 0.53 | ethambutol | |
embB | 4248200 | p.Ile563Val | missense_variant | 0.53 | ethambutol | |
embB | 4248205 | c.1692C>G | synonymous_variant | 0.5 | ethambutol | |
embB | 4248206 | c.1693_1695delAGCinsGT | frameshift_variant&missense_variant | 0.5 | ethambutol | |
embB | 4248220 | c.1707A>C | synonymous_variant | 0.55 | ethambutol | |
embB | 4248304 | c.1791G>C | synonymous_variant | 0.59 | ethambutol | |
embB | 4248316 | c.1803C>G | synonymous_variant | 0.55 | ethambutol | |
embB | 4248319 | c.1806A>G | synonymous_variant | 0.56 | ethambutol | |
embB | 4248373 | c.1860C>G | synonymous_variant | 0.45 | ethambutol | |
embB | 4248382 | c.1869C>G | synonymous_variant | 0.44 | ethambutol | |
embB | 4248386 | c.1873C>A | synonymous_variant | 0.35 | ethambutol | |
embB | 4249417 | c.2904A>G | synonymous_variant | 0.77 | ethambutol | |
embB | 4249423 | p.Asp970Glu | missense_variant | 0.69 | ethambutol | Uncertain significance |
embB | 4249424 | p.Leu971Met | missense_variant | 0.69 | ethambutol | |
embB | 4249429 | c.2916C>T | synonymous_variant | 0.73 | ethambutol | |
embB | 4249432 | c.2919A>G | synonymous_variant | 0.79 | ethambutol | |
embB | 4249441 | c.2928A>G | synonymous_variant | 0.8 | ethambutol | Not assoc w R - Interim |
embB | 4249444 | c.2931T>C | synonymous_variant | 0.8 | ethambutol | |
embB | 4249469 | p.Leu986Met | missense_variant | 0.76 | ethambutol | |
embB | 4249486 | c.2973T>G | synonymous_variant | 0.73 | ethambutol | |
embB | 4249498 | c.2985G>C | synonymous_variant | 0.67 | ethambutol | |
embB | 4249521 | p.Ala1003Val | missense_variant | 0.65 | ethambutol | |
embB | 4249525 | c.3012T>C | synonymous_variant | 0.62 | ethambutol | Not assoc w R - Interim |
embB | 4249529 | p.Ile1006Val | missense_variant | 0.58 | ethambutol | |
embB | 4249532 | p.Ala1007Thr | missense_variant | 0.58 | ethambutol | Uncertain significance |
embB | 4249537 | c.3024A>G | synonymous_variant | 0.58 | ethambutol | |
embB | 4249543 | c.3030G>C | synonymous_variant | 0.58 | ethambutol | |
embB | 4249546 | c.3033G>A | synonymous_variant | 0.55 | ethambutol | |
aftB | 4268994 | c.-158T>G | upstream_gene_variant | 0.39 | ethambutol | |
ubiA | 4268999 | c.835C>T | synonymous_variant | 0.42 | ethambutol | Not assoc w R - Interim |
aftB | 4269006 | c.-170T>C | upstream_gene_variant | 0.45 | ethambutol | |
aftB | 4269012 | c.-176G>C | upstream_gene_variant | 0.41 | ethambutol | |
ubiA | 4269027 | c.807C>T | synonymous_variant | 0.41 | ethambutol | Not assoc w R - Interim |
aftB | 4269033 | c.-197T>C | upstream_gene_variant | 0.47 | ethambutol | |
aftB | 4269036 | c.-200C>G | upstream_gene_variant | 0.47 | ethambutol | |
aftB | 4269042 | c.-206G>C | upstream_gene_variant | 0.45 | ethambutol | |
aftB | 4269201 | c.-365A>G | upstream_gene_variant | 0.8 | ethambutol | |
aftB | 4269206 | c.-370C>T | upstream_gene_variant | 0.73 | ethambutol | |
ubiA | 4269220 | p.Ala205Lys | missense_variant | 0.62 | ethambutol | |
ubiA | 4269222 | c.612T>C | synonymous_variant | 0.62 | ethambutol | Not assoc w R - Interim |
aftB | 4269242 | c.-406C>T | upstream_gene_variant | 0.47 | ethambutol | |
ubiA | 4269243 | p.His197Gln | missense_variant | 0.47 | ethambutol | |
aftB | 4269249 | c.-413G>A | upstream_gene_variant | 0.44 | ethambutol | |
aftB | 4269258 | c.-422C>T | upstream_gene_variant | 0.44 | ethambutol |