TB-Profiler result

Run: SRR1172857
Summary

Run ID: SRR1172857

Sample name:

Date: 2024-05-22T17:17:21.289446

Number of reads: 566017

Percentage reads mapped: 45.32

Median coverage: 12.0

Strain:

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.2.BCG M.bovis None 0.07
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.His312Arg Mutation from literature
pyrazinamide panD p.Val138Ala Mutation from literature
streptomycin rpsL p.Lys43Arg Assoc w R
rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fbiC c.859_861delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpsL 781687 p.Lys43Arg missense_variant 0.41 streptomycin Assoc w R
fbiC 1303789 c.859_861delATCinsGG frameshift_variant&missense_variant 0.6 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance Mutation from literature
panD 4043869 p.Val138Ala missense_variant 0.4 pyrazinamide Mutation from literature
embB 4247448 p.His312Arg missense_variant 0.61 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 627 c.627G>A synonymous_variant 0.55 isoniazid
dnaA 693 c.693A>G synonymous_variant 0.4 isoniazid Not assoc w R - Interim
dnaA 705 c.705A>G synonymous_variant 0.53 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.47 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.44 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.47 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.47 isoniazid
dnaA 768 c.768C>G synonymous_variant 0.53 isoniazid
dnaA 771 c.771A>C synonymous_variant 0.47 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.52 isoniazid
dnaA 786 c.786C>T synonymous_variant 0.47 isoniazid
dnaA 792 c.792C>T synonymous_variant 0.48 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.43 isoniazid Not assoc w R - Interim
dnaA 942 c.942C>G synonymous_variant 0.5 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.48 isoniazid
dnaA 955 c.955A>C synonymous_variant 0.48 isoniazid
dnaA 960 c.960C>A synonymous_variant 0.53 isoniazid
dnaA 963 c.963C>G synonymous_variant 0.5 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.47 isoniazid
dnaA 969 c.969G>A synonymous_variant 0.5 isoniazid
dnaA 975 c.975G>T synonymous_variant 0.47 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.5 isoniazid Not assoc w R - Interim
dnaA 1197 c.1197T>C synonymous_variant 0.5 isoniazid Not assoc w R - Interim
dnaA 1204 c.1204C>T synonymous_variant 0.55 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.48 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.48 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 0.52 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.56 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.55 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.57 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.58 isoniazid
dnaA 1284 c.1284C>G synonymous_variant 0.56 isoniazid
dnaA 1290 c.1290G>A synonymous_variant 0.46 isoniazid
dnaA 1293 c.1293T>C synonymous_variant 0.42 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 0.33 isoniazid Not assoc w R - Interim
dnaA 1404 c.1404T>C synonymous_variant 0.33 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.32 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.35 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.33 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 0.32 isoniazid
dnaA 1449 c.1449G>A synonymous_variant 0.26 isoniazid
dnaA 1461 c.1461C>G synonymous_variant 0.23 isoniazid
dnaA 1470 c.1470C>T synonymous_variant 0.23 isoniazid
gyrB 6136 c.897G>A synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6139 c.900G>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrB 6256 c.1017G>A synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrB 6268 c.1029C>G synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrB 6289 c.1050C>T synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6346 c.1107C>T synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6362 c.-940T>C upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrB 7186 c.1947C>G synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7317 c.16T>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 7324 c.23_24insAGG disruptive_inframe_insertion 0.41 levofloxacin
moxifloxacin
gyrA 7334 c.33G>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 7335 p.Leu12Val missense_variant 0.41 levofloxacin
moxifloxacin
gyrA 7347 c.46_48delGAAinsCG frameshift_variant&missense_variant 0.41 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7532 c.231T>G synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8121 c.820T>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8129 c.828T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8135 c.834C>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.5 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.44 levofloxacin
moxifloxacin
gyrA 8387 c.1086C>T synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 0.38 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8576 c.1275C>G synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8579 c.1278C>T synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8588 c.1287G>A synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8619 c.1318_1320delTTGinsCA frameshift_variant&missense_variant 0.4 levofloxacin
moxifloxacin
gyrA 8624 c.1323G>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8891 c.1590G>A synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.69 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 0.38 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>G synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 9122 c.1821C>G synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9161 c.1860C>G synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 0.54 levofloxacin
moxifloxacin
gyrA 9224 c.1923C>T synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>T synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9252 p.Val651Ile missense_variant 0.56 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9284 c.1983T>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>C synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9300 p.Ala667Ser missense_variant 0.4 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Asp missense_variant 0.42 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9308 p.Asp669Glu missense_variant 0.46 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9335 c.2034G>C synonymous_variant 0.53 levofloxacin
moxifloxacin
fgd1 490827 c.45C>T synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fgd1 490848 c.66A>G synonymous_variant 0.55 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490851 c.69A>T synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fgd1 490868 p.Ala29Gly missense_variant 0.56 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>A synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>G synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fgd1 491535 c.753G>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491553 c.771G>A synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.63 clofazimine
pretomanid
delamanid
mshA 575576 c.229C>T synonymous_variant 0.38 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575581 c.234C>T synonymous_variant 0.38 ethionamide
isoniazid
mshA 575587 c.240C>G synonymous_variant 0.35 ethionamide
isoniazid
mshA 575590 c.243T>C synonymous_variant 0.38 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 0.47 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.44 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.39 ethionamide
isoniazid
mshA 575749 c.402C>A synonymous_variant 0.41 ethionamide
isoniazid
mshA 575752 c.405G>C synonymous_variant 0.39 ethionamide
isoniazid
mshA 575755 c.408G>A synonymous_variant 0.39 ethionamide
isoniazid
mshA 575756 c.409C>T synonymous_variant 0.39 ethionamide
isoniazid
mshA 575770 c.423G>A synonymous_variant 0.44 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.44 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.44 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.47 ethionamide
isoniazid
mshA 575809 c.462C>T synonymous_variant 0.5 ethionamide
isoniazid
mshA 575812 c.465C>T synonymous_variant 0.5 ethionamide
isoniazid
ccsA 620385 c.495G>C synonymous_variant 0.47 capreomycin
amikacin
kanamycin
Rv0565c 657300 c.171C>G synonymous_variant 0.8 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.77 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 0.75 ethionamide
Rv0565c 657327 c.144C>G synonymous_variant 0.7 ethionamide
Rv0565c 657337 p.Arg45Gln missense_variant 0.75 ethionamide Uncertain significance
Rv0565c 657342 c.129T>C synonymous_variant 0.69 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 0.64 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 0.64 ethionamide
Rv0565c 657356 p.Ile39Val missense_variant 0.67 ethionamide
Rv0565c 657372 c.99G>C synonymous_variant 0.55 ethionamide
Rv0565c 657375 c.96C>T synonymous_variant 0.5 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.58 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.57 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.55 ethionamide
Rv0565c 657678 c.-209_-208delAAinsTC upstream_gene_variant 0.62 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAC upstream_gene_variant 0.62 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.62 ethionamide
hadA 731774 c.-156T>C upstream_gene_variant 0.33 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.32 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.3 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.3 isoniazid
hadA 732272 p.Ala115Ser missense_variant 0.5 isoniazid
hadA 732295 c.366G>C synonymous_variant 0.47 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.53 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.56 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.6 isoniazid
hadA 732329 p.Leu134Val missense_variant 0.59 isoniazid Uncertain significance
hadA 732337 c.408G>A synonymous_variant 0.57 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.59 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.61 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.62 isoniazid
nusG 734120 c.-134T>C upstream_gene_variant 0.47 rifampicin Uncertain significance
nusG 734123 c.-131C>G upstream_gene_variant 0.47 rifampicin
nusG 734129 c.-125G>C upstream_gene_variant 0.44 rifampicin
nusG 734132 c.-122G>C upstream_gene_variant 0.44 rifampicin
nusG 734135 c.-119G>C upstream_gene_variant 0.47 rifampicin
nusG 734144 c.-110G>C upstream_gene_variant 0.39 rifampicin
nusG 734376 c.123G>A synonymous_variant 0.47 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.55 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.58 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.59 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.68 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.69 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.7 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.73 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.77 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 0.58 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.57 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.42 rifampicin
rpoB 760101 c.295T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.39 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.56 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.62 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.62 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.46 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.52 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.47 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.5 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.57 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.62 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.62 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.74 rifampicin
rpoB 760412 c.606C>G synonymous_variant 0.74 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760472 c.666C>T synonymous_variant 0.6 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.52 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.52 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.57 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.64 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.4 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 0.36 rifampicin
rpoB 760757 c.951T>C synonymous_variant 0.42 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.42 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.47 rifampicin
rpoB 760775 c.969G>C synonymous_variant 0.47 rifampicin
rpoB 760776 c.970_972delTCGinsAGC synonymous_variant 0.47 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 0.57 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Ile missense_variant 0.5 rifampicin Uncertain significance
rpoB 760886 c.1080A>G synonymous_variant 0.65 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.59 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.62 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 0.68 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.61 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.74 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 0.74 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.65 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.75 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.75 rifampicin
rpoB 761219 c.1413G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 0.67 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.53 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.42 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 0.71 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.68 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761588 c.1782C>T synonymous_variant 0.75 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.7 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 761778 p.Asn658Asp missense_variant 0.57 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.64 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.69 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.69 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.56 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.43 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.47 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.44 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.46 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.43 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.42 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.43 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.43 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.43 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.43 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.8 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.61 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.64 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.56 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.56 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762206 c.2400C>G synonymous_variant 0.65 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 762246 c.2440C>T synonymous_variant 0.61 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.59 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.6 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.62 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762314 c.2508C>T synonymous_variant 0.57 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.56 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.53 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.56 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 762467 c.-903C>T upstream_gene_variant 0.44 rifampicin
rpoB 762488 c.2682G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.42 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.48 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.48 rifampicin
rpoC 762521 c.-849C>T upstream_gene_variant 0.48 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.39 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.71 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763013 c.-357C>G upstream_gene_variant 0.72 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763067 c.-303C>G upstream_gene_variant 0.58 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.63 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.66 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 763190 c.-180C>T upstream_gene_variant 0.61 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.54 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.48 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.48 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.52 rifampicin
rpoB 763227 c.3421C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 763238 c.3432T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.37 rifampicin
rpoC 763256 c.-114G>A upstream_gene_variant 0.37 rifampicin
rpoC 763402 c.33C>G synonymous_variant 0.66 rifampicin
rpoC 763411 c.42T>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.62 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.67 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.49 rifampicin
rpoC 763492 c.123G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763606 c.237C>T synonymous_variant 0.72 rifampicin
rpoC 763636 c.267T>C synonymous_variant 0.61 rifampicin
rpoC 763657 c.288G>A synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.52 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.56 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.59 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.59 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.53 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.56 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.52 rifampicin
rpoC 763853 p.Val162Ile missense_variant 0.32 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.36 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.38 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.38 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.42 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.38 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764083 c.714A>G synonymous_variant 0.56 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.72 rifampicin
rpoC 764112 p.Tyr248Phe missense_variant 0.71 rifampicin
rpoC 764116 c.747C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.74 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ile missense_variant 0.47 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.41 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764215 c.846A>G synonymous_variant 0.58 rifampicin
rpoC 764236 c.867G>A synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764248 c.879C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.65 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.6 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.54 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.57 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764338 c.969G>A synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036A>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.42 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.48 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.48 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.48 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.55 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.4 rifampicin
rpoC 764551 c.1182G>C synonymous_variant 0.4 rifampicin
rpoC 764554 c.1185C>T synonymous_variant 0.4 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764593 c.1224C>T synonymous_variant 0.45 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 0.8 rifampicin
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.8 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.53 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.76 rifampicin
rpoC 764932 c.1563C>A synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.53 rifampicin Not assoc w R
rpoC 765007 c.1638T>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1643delAGinsTC synonymous_variant 0.47 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.42 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765421 c.2052C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.88 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.86 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.86 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.81 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.76 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.67 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.56 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.69 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.71 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.71 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.67 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.67 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.69 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.69 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.69 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.62 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.67 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.8 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.75 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.76 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.72 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.74 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.67 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.71 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.78 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.71 rifampicin
rpoC 766132 c.2763C>T synonymous_variant 0.67 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.62 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.43 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.45 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 0.43 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.42 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.42 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.42 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.42 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 0.5 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.47 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.5 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 0.47 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.62 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 0.62 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.62 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.65 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.5 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.47 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.38 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.38 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.53 rifampicin
rpoC 766795 c.3426C>T synonymous_variant 0.64 rifampicin
rpoC 766801 c.3432C>G synonymous_variant 0.67 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.7 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.87 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.6 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 0.45 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.43 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.57 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.56 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.47 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 776672 c.1809G>C synonymous_variant 0.43 clofazimine
bedaquiline
mmpL5 776675 c.1806G>A synonymous_variant 0.43 clofazimine
bedaquiline
mmpL5 776684 c.1797G>A synonymous_variant 0.43 clofazimine
bedaquiline
mmpL5 776687 p.Trp598Phe missense_variant 0.41 clofazimine
bedaquiline
mmpL5 776695 p.Val596Ile missense_variant 0.39 clofazimine
bedaquiline
mmpL5 776738 c.1743C>T synonymous_variant 0.41 clofazimine
bedaquiline
mmpL5 777164 c.1317C>G synonymous_variant 0.54 clofazimine
bedaquiline
mmpL5 777170 c.1311T>C synonymous_variant 0.53 clofazimine
bedaquiline
mmpL5 777176 p.Glu435Asp missense_variant 0.5 clofazimine
bedaquiline
mmpL5 777191 c.1290C>G synonymous_variant 0.5 clofazimine
bedaquiline
mmpL5 777194 c.1287A>G synonymous_variant 0.47 clofazimine
bedaquiline
mmpL5 777206 c.1275A>G synonymous_variant 0.44 clofazimine
bedaquiline
mmpL5 777212 c.1267_1269delGCCinsAG frameshift_variant&missense_variant 0.37 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 777215 c.1266C>G synonymous_variant 0.32 clofazimine
bedaquiline
mmpL5 777218 c.1263G>A synonymous_variant 0.32 clofazimine
bedaquiline
rpsL 781628 c.69T>C synonymous_variant 0.57 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.56 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.64 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.63 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.65 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.68 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.67 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.72 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.69 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.69 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.67 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.67 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.69 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.59 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.59 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.54 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.56 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.54 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.54 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.54 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.56 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.57 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.58 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.58 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.73 streptomycin Uncertain significance
rplC 800516 c.-293G>T upstream_gene_variant 0.67 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.62 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.62 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 0.67 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.67 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.64 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.71 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.71 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.75 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.72 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.76 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.78 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.78 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.72 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.68 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.72 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.73 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.68 linezolid
rplC 800794 c.-15A>G upstream_gene_variant 0.62 linezolid
rplC 800796 c.-13A>G upstream_gene_variant 0.62 linezolid
rplC 800798 c.-10_-9delGG upstream_gene_variant 0.6 linezolid
rplC 800814 c.6A>G synonymous_variant 0.59 linezolid
rplC 800817 c.9A>T synonymous_variant 0.62 linezolid
rplC 800844 c.36T>C synonymous_variant 0.53 linezolid
rplC 801348 c.540T>G synonymous_variant 0.46 linezolid
rplC 801357 c.549T>C synonymous_variant 0.5 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.5 linezolid
rplC 801402 c.594T>C synonymous_variant 0.4 linezolid
rplC 801405 c.597T>C synonymous_variant 0.38 linezolid
rplC 801423 c.615G>C synonymous_variant 0.47 linezolid
fbiC 1303521 c.591C>T synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1303530 c.600G>A synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1303534 p.Ser202Ala missense_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1303539 c.609G>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1303728 c.798G>A synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 0.63 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1303761 c.831T>C synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1303797 c.867A>G synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1303836 c.906G>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1303845 c.915C>G synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1303846 p.Phe306Val missense_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304553 c.1623C>T synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>C synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>G synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>T synonymous_variant 0.79 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304891 p.Ile654Thr missense_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1305384 c.2454G>C synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1305396 c.2466C>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>G synonymous_variant 0.47 clofazimine Not assoc w R - Interim
pretomanid
delamanid
sigE 1365033 c.621G>A synonymous_variant 0.38 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 0.38 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.44 pyrazinamide
sigE 1365057 c.645C>T synonymous_variant 0.47 pyrazinamide
sigE 1365063 c.651A>C synonymous_variant 0.5 pyrazinamide
sigE 1365084 c.672G>C synonymous_variant 0.43 pyrazinamide
sigE 1365087 c.675A>C synonymous_variant 0.43 pyrazinamide
sigE 1365090 c.678T>C synonymous_variant 0.46 pyrazinamide
sigE 1365096 c.684G>C synonymous_variant 0.55 pyrazinamide
sigE 1365099 c.687A>C synonymous_variant 0.55 pyrazinamide
atpE 1461170 c.126A>G synonymous_variant 0.45 bedaquiline
atpE 1461185 c.141G>T synonymous_variant 0.52 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.48 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.36 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.36 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 0.36 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.38 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.57 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.52 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.54 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.43 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.45 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.37 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.37 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.37 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.39 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.39 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.39 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.47 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472045 n.200T>A non_coding_transcript_exon_variant 0.5 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.55 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.55 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.6 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.59 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.51 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.53 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.59 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.59 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.64 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.66 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.72 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473677 n.20C>G non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1473987 n.330G>A non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1474960 n.1303C>G non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1474963 n.1306G>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1474965 n.1308G>C non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475267 n.1610G>A non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.65 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.71 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.52 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476031 n.2374C>T non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1476214 n.2557G>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.65 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.68 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1476733 n.3076C>T non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
inhA 1673547 c.-655T>C upstream_gene_variant 0.39 ethionamide
isoniazid
fabG1 1673548 p.Ala37Thr missense_variant 0.39 ethionamide
isoniazid
inhA 1673679 c.-523T>G upstream_gene_variant 0.43 ethionamide
isoniazid
inhA 1673685 c.-517C>T upstream_gene_variant 0.4 ethionamide
isoniazid
fabG1 1673716 p.Ala93Lys missense_variant 0.42 ethionamide
isoniazid
fabG1 1673733 p.Met98Ile missense_variant 0.5 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 0.67 ethionamide
isoniazid
inhA 1673946 c.-256C>G upstream_gene_variant 0.62 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 0.62 ethionamide
isoniazid
inhA 1673961 c.-241A>C upstream_gene_variant 0.57 ethionamide
isoniazid
inhA 1673985 c.-217C>G upstream_gene_variant 0.5 ethionamide
isoniazid
fabG1 1674006 p.Asp189Glu missense_variant 0.53 ethionamide
isoniazid
inhA 1674015 c.-187C>T upstream_gene_variant 0.46 ethionamide
isoniazid Uncertain significance
inhA 1674018 c.-184G>C upstream_gene_variant 0.46 ethionamide
isoniazid
inhA 1674021 c.-181G>C upstream_gene_variant 0.5 ethionamide
isoniazid
inhA 1674024 c.-178T>C upstream_gene_variant 0.5 ethionamide
isoniazid
inhA 1674063 c.-139G>C upstream_gene_variant 0.7 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 0.83 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 0.58 ethionamide
isoniazid
inhA 1674630 c.429C>G synonymous_variant 0.57 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 0.54 ethionamide
isoniazid
inhA 1674672 c.471C>G synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 0.55 ethionamide
isoniazid
inhA 1674708 c.507G>A synonymous_variant 0.47 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 0.39 ethionamide
isoniazid
inhA 1674822 c.621C>G synonymous_variant 0.4 ethionamide
isoniazid
inhA 1674828 c.627G>A synonymous_variant 0.38 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 0.52 ethionamide
isoniazid
inhA 1674864 c.663C>T synonymous_variant 0.57 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674870 c.669T>C synonymous_variant 0.65 ethionamide
isoniazid
inhA 1674879 c.678T>C synonymous_variant 0.68 ethionamide
isoniazid
inhA 1674900 c.699G>A synonymous_variant 0.6 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 0.63 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 0.67 ethionamide
isoniazid
inhA 1674909 c.708G>A synonymous_variant 0.71 ethionamide
isoniazid
inhA 1674942 c.741T>G synonymous_variant 0.64 ethionamide
isoniazid
rpsA 1833554 p.Thr5Ala missense_variant 0.6 pyrazinamide Uncertain significance
rpsA 1833568 c.27G>C synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.56 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.56 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.57 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.59 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.63 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.61 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.63 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.63 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.63 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.68 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.67 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.67 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.64 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.59 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.52 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.5 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.47 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.58 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.52 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.53 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.57 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.58 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.6 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.59 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.67 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.62 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.69 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.75 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.69 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 0.69 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.75 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.71 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.64 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 0.64 pyrazinamide Uncertain significance
rpsA 1834162 c.621A>G synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.5 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.5 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.55 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.53 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.55 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.45 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.45 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.38 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.43 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.56 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.55 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.6 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.52 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.57 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.52 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.44 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.48 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.42 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.42 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.48 pyrazinamide
rpsA 1834510 c.969C>T synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
rpsA 1834513 c.972C>G synonymous_variant 0.58 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.61 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.71 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.72 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.64 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.6 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.56 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.48 pyrazinamide
rpsA 1834684 c.1143C>T synonymous_variant 0.52 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.43 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.43 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.41 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.58 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.5 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 0.5 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.52 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.54 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.59 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.57 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.55 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.52 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.53 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.57 linezolid
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
bacA 2064972 c.-244T>C upstream_gene_variant 0.73 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 0.75 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 0.75 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.75 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.86 streptomycin
kanamycin
capreomycin
amikacin
ndh 2102686 c.357G>C synonymous_variant 0.38 ethionamide
delamanid
isoniazid
ndh 2102695 c.348C>T synonymous_variant 0.38 ethionamide
delamanid
isoniazid
ndh 2102700 c.343C>T synonymous_variant 0.4 ethionamide
delamanid
isoniazid
ndh 2102710 c.333C>T synonymous_variant 0.35 ethionamide
delamanid
isoniazid
katG 2155677 c.435C>G synonymous_variant 0.79 isoniazid
katG 2155680 c.432G>C synonymous_variant 0.8 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.93 isoniazid
katG 2155695 c.417C>G synonymous_variant 0.94 isoniazid
katG 2155704 c.408C>G synonymous_variant 0.94 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.82 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.76 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.71 isoniazid
katG 2155740 p.Gly124Gln missense_variant 0.56 isoniazid
katG 2155743 c.369G>C synonymous_variant 0.56 isoniazid
PPE35 2170892 c.-280G>A upstream_gene_variant 0.95 pyrazinamide
pncA 2289930 c.-689A>G upstream_gene_variant 0.44 pyrazinamide
pncA 2289943 c.-702T>G upstream_gene_variant 0.47 pyrazinamide
pncA 2289948 c.-707C>T upstream_gene_variant 0.47 pyrazinamide
pncA 2289949 c.-708A>G upstream_gene_variant 0.47 pyrazinamide
pncA 2289987 c.-746C>T upstream_gene_variant 0.56 pyrazinamide
pncA 2289991 c.-750G>C upstream_gene_variant 0.53 pyrazinamide
pncA 2289994 c.-753A>G upstream_gene_variant 0.53 pyrazinamide
pncA 2289997 c.-756G>C upstream_gene_variant 0.6 pyrazinamide
pncA 2290009 c.-768A>G upstream_gene_variant 0.69 pyrazinamide
pncA 2290015 c.-774A>C upstream_gene_variant 0.69 pyrazinamide
pncA 2290024 c.-783C>G upstream_gene_variant 0.67 pyrazinamide
kasA 2517950 c.-165C>G upstream_gene_variant 0.75 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.64 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.62 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.44 isoniazid
kasA 2518138 c.24T>C synonymous_variant 0.43 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 0.47 isoniazid
kasA 2518162 c.48G>A synonymous_variant 0.59 isoniazid
kasA 2518174 c.60A>G synonymous_variant 0.59 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.5 isoniazid
kasA 2518199 p.Ile29Val missense_variant 0.5 isoniazid
kasA 2518220 c.106C>T synonymous_variant 0.43 isoniazid
kasA 2518234 c.120G>A synonymous_variant 0.39 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.64 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.58 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.57 isoniazid
kasA 2518696 c.582C>G synonymous_variant 0.57 isoniazid
kasA 2518702 c.588C>T synonymous_variant 0.57 isoniazid
kasA 2518705 c.591T>C synonymous_variant 0.57 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.62 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.64 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.58 isoniazid
kasA 2518744 c.630C>T synonymous_variant 0.56 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.56 isoniazid
kasA 2518768 c.654C>T synonymous_variant 0.5 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.5 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.5 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.5 isoniazid
kasA 2518792 c.678C>A synonymous_variant 0.43 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.43 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.56 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.5 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.52 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.52 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.52 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 0.69 isoniazid
kasA 2519107 c.993T>C synonymous_variant 0.85 isoniazid
kasA 2519108 c.994_996delGATinsCG frameshift_variant&missense_variant 0.85 isoniazid
kasA 2519122 c.1008G>C synonymous_variant 0.75 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.64 isoniazid
kasA 2519158 c.1044C>T synonymous_variant 0.6 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.69 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 0.57 isoniazid
ahpC 2726336 c.144G>C synonymous_variant 0.37 isoniazid
ahpC 2726348 c.156T>C synonymous_variant 0.5 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 0.5 isoniazid Not assoc w R - Interim
ahpC 2726564 c.372C>G synonymous_variant 0.53 isoniazid Not assoc w R - Interim
ahpC 2726591 c.399C>G synonymous_variant 0.67 isoniazid
ahpC 2726593 p.Val134Ala missense_variant 0.67 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 0.65 isoniazid
ahpC 2726601 p.Ile137Leu missense_variant 0.68 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 0.68 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 0.67 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 0.7 isoniazid Not assoc w R - Interim
ahpC 2726669 p.Asp159Glu missense_variant 0.56 isoniazid
ahpC 2726672 c.480G>A synonymous_variant 0.58 isoniazid Not assoc w R - Interim
ahpC 2726675 c.483A>G synonymous_variant 0.54 isoniazid
ahpC 2726681 c.489A>C synonymous_variant 0.48 isoniazid Not assoc w R - Interim
ahpC 2726687 c.495C>G synonymous_variant 0.45 isoniazid
ahpC 2726693 c.501C>G synonymous_variant 0.43 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.42 isoniazid
folC 2747275 c.324T>C synonymous_variant 0.6 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 0.67 para-aminosalicylic_acid
Rv2477c 2782441 c.1602G>A synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782450 c.1593C>A synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782453 c.1590C>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782513 c.1530G>T synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782522 c.1521G>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782546 c.1497C>G synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 0.4 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782966 c.1077C>A synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782969 c.1074A>C synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782972 c.1071G>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 0.35 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783015 p.Ser343Thr missense_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.47 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 0.47 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783101 c.942G>T synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783107 c.936G>A synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 0.59 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.57 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783182 c.861C>G synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783185 c.858G>A synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 0.85 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783275 c.768C>G synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783929 c.114C>G synonymous_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783932 c.111C>T synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.31 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 0.3 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783962 c.81T>C synonymous_variant 0.33 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 0.34 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.38 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784396 c.-354A>C upstream_gene_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784405 c.-363T>C upstream_gene_variant 0.32 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784428 c.-386T>C upstream_gene_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784429 c.-387A>G upstream_gene_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784432 c.-390A>C upstream_gene_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784435 c.-393C>G upstream_gene_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784452 c.-410C>T upstream_gene_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784454 c.-412G>A upstream_gene_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784456 c.-414A>C upstream_gene_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784472 c.-430C>A upstream_gene_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784477 c.-435T>C upstream_gene_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2752c 3065988 c.204A>G synonymous_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065993 p.Val67Ile missense_variant 0.4 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3066018 c.174T>C synonymous_variant 0.43 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066024 c.168T>G synonymous_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066118 p.Asn25Ser missense_variant 0.29 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066261 c.-70G>C upstream_gene_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066270 c.-79G>A upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066276 c.-85G>A upstream_gene_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066279 c.-88A>G upstream_gene_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066282 c.-91G>T upstream_gene_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066287 c.-96G>C upstream_gene_variant 0.39 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066290 c.-99G>A upstream_gene_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066291 c.-100G>A upstream_gene_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066309 c.-118T>C upstream_gene_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066330 c.-139G>C upstream_gene_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066807 c.-616T>C upstream_gene_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066810 c.-619G>A upstream_gene_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067349 c.597G>C synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.61 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.67 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.74 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067442 c.504C>T synonymous_variant 0.72 para-aminosalicylic_acid
thyX 3067445 c.501C>G synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067462 c.484C>T synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067465 p.Ile161Val missense_variant 0.73 para-aminosalicylic_acid
thyX 3067466 c.480G>C synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067490 c.456C>G synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067493 c.453A>G synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067510 c.436C>T synonymous_variant 0.54 para-aminosalicylic_acid
thyX 3067515 p.Ser144Thr missense_variant 0.58 para-aminosalicylic_acid
thyX 3067530 p.Ala139Ser missense_variant 0.58 para-aminosalicylic_acid
thyX 3067545 p.Glu134Ala missense_variant 0.75 para-aminosalicylic_acid
thyX 3067549 p.Thr133Ala missense_variant 0.64 para-aminosalicylic_acid
thyX 3067556 p.His130Gln missense_variant 0.67 para-aminosalicylic_acid
thyX 3067559 c.387C>G synonymous_variant 0.67 para-aminosalicylic_acid
thyX 3067565 p.Asp127Glu missense_variant 0.69 para-aminosalicylic_acid
thyX 3067570 p.Ala126Pro missense_variant 0.69 para-aminosalicylic_acid
thyX 3067577 c.369G>A synonymous_variant 0.71 para-aminosalicylic_acid
thyX 3067601 p.Arg115His missense_variant 0.77 para-aminosalicylic_acid
thyX 3067611 p.Lys112Thr missense_variant 0.69 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 0.67 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.65 para-aminosalicylic_acid
thyX 3067685 c.261A>C synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067691 c.253_255delATCinsCG frameshift_variant&missense_variant 0.59 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.59 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.69 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.72 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.84 para-aminosalicylic_acid
thyX 3067736 c.210C>T synonymous_variant 0.88 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.79 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.79 para-aminosalicylic_acid
thyX 3067772 c.174C>G synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067775 c.171C>T synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.67 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.44 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.47 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.5 para-aminosalicylic_acid
thyX 3067877 c.69G>C synonymous_variant 0.47 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.44 para-aminosalicylic_acid
thyX 3067886 c.60A>C synonymous_variant 0.44 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.47 para-aminosalicylic_acid
thyX 3067894 c.52T>C synonymous_variant 0.47 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 0.47 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.77 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.44 para-aminosalicylic_acid
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0 ethionamide Uncertain significance
lpqB 3623512 p.Gly467Ser missense_variant 0.46 bedaquiline
rifampicin
lpqB 3623531 c.1380T>C synonymous_variant 0.35 bedaquiline
rifampicin
lpqB 3623549 c.1362C>G synonymous_variant 0.44 bedaquiline
rifampicin
lpqB 3623555 c.1354_1356delGGGinsAC frameshift_variant&missense_variant 0.44 bedaquiline
rifampicin Uncertain significance
lpqB 3623561 c.1350T>C synonymous_variant 0.47 bedaquiline
rifampicin
lpqB 3623570 c.1341A>G synonymous_variant 0.43 bedaquiline
rifampicin
lpqB 3623573 c.1338T>G synonymous_variant 0.4 bedaquiline
rifampicin
lpqB 3623576 c.1335T>C synonymous_variant 0.4 bedaquiline
rifampicin
lpqB 3623580 p.Asn444Thr missense_variant 0.38 bedaquiline
rifampicin
lpqB 3625543 c.-633G>C upstream_gene_variant 0.38 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 0.5 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625572 p.Thr348Ser missense_variant 0.47 bedaquiline
rifampicin
lpqB 3625579 c.-669A>G upstream_gene_variant 0.53 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 0.47 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 0.47 bedaquiline
rifampicin
lpqB 3625612 c.-702G>C upstream_gene_variant 0.47 bedaquiline
rifampicin
mtrB 3625616 p.Arg333Ala missense_variant 0.44 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 0.44 bedaquiline
rifampicin
mtrB 3625636 c.978C>G synonymous_variant 0.54 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625705 c.909C>G synonymous_variant 0.58 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625711 c.903C>T synonymous_variant 0.57 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625714 c.-804C>T upstream_gene_variant 0.56 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 0.65 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.6 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625735 c.-825C>T upstream_gene_variant 0.58 bedaquiline
rifampicin
lpqB 3625749 c.-839C>T upstream_gene_variant 0.58 bedaquiline
rifampicin
mtrB 3625755 p.Ala287Thr missense_variant 0.63 bedaquiline
rifampicin Uncertain significance
mtrB 3625765 c.849C>G synonymous_variant 0.65 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625774 c.840G>A synonymous_variant 0.65 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625797 p.Val273Met missense_variant 0.71 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625806 c.808A>C synonymous_variant 0.62 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625807 c.807C>G synonymous_variant 0.59 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625837 c.777C>G synonymous_variant 0.62 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625849 c.-939T>C upstream_gene_variant 0.58 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.55 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 0.53 bedaquiline
rifampicin
mtrB 3626687 c.-74G>T upstream_gene_variant 0.4 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 0.58 bedaquiline
rifampicin
mtrB 3626711 c.-98T>C upstream_gene_variant 0.62 bedaquiline
rifampicin
mtrA 3626723 c.627C>T synonymous_variant 0.69 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626726 c.-113T>C upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrA 3626759 c.591T>C synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626774 c.574_576delAGGinsCC frameshift_variant&missense_variant 0.88 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 0.87 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 0.87 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626795 c.-182C>T upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3626798 c.-185T>C upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626840 c.-227C>G upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.87 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626858 c.-245A>G upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrA 3626869 c.481C>T synonymous_variant 0.8 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626876 c.-263A>G upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3626885 c.-272A>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3626903 c.-290T>C upstream_gene_variant 0.54 bedaquiline
rifampicin
mtrA 3626969 c.381C>T synonymous_variant 0.54 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626972 c.-359A>G upstream_gene_variant 0.54 bedaquiline
rifampicin
mtrB 3626987 c.-374C>G upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 0.54 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 0.6 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>C upstream_gene_variant 0.6 bedaquiline
rifampicin
mtrA 3627146 c.204C>T synonymous_variant 0.73 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627167 c.-554T>C upstream_gene_variant 0.65 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 0.62 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.6 bedaquiline
rifampicin
mtrA 3627188 c.162A>G synonymous_variant 0.59 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627209 c.-596G>A upstream_gene_variant 0.65 bedaquiline
rifampicin
mtrA 3627221 c.129C>T synonymous_variant 0.67 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627227 c.123T>C synonymous_variant 0.68 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627233 c.-620T>C upstream_gene_variant 0.65 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 0.65 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 0.62 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627254 c.-641C>T upstream_gene_variant 0.55 bedaquiline
rifampicin
mtrB 3627263 c.-650C>T upstream_gene_variant 0.6 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 0.6 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 0.59 bedaquiline
rifampicin
mtrB 3627275 c.-662G>T upstream_gene_variant 0.59 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 0.58 bedaquiline
rifampicin
mtrA 3627299 c.49_51delTTGinsCA frameshift_variant&missense_variant 0.58 bedaquiline
rifampicin
mtrB 3627314 c.-701C>T upstream_gene_variant 0.63 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.62 bedaquiline
rifampicin
rpoA 3877503 c.1005G>C synonymous_variant 0.54 rifampicin
rpoA 3877507 p.Gly334Ala missense_variant 0.6 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 0.58 rifampicin
rpoA 3877553 p.Glu319Gln missense_variant 0.67 rifampicin
rpoA 3877571 p.Pro313Ala missense_variant 0.71 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.65 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.45 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 0.44 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.48 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.48 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoA 3877791 c.717C>G synonymous_variant 0.57 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.5 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.5 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 0.48 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 0.5 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.53 rifampicin
rpoA 3878001 c.507A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.54 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.52 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.54 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3878055 c.453A>G synonymous_variant 0.45 rifampicin
rpoA 3878058 c.450G>T synonymous_variant 0.45 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.42 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 0.44 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.44 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.5 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.64 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 0.56 rifampicin
rpoA 3878187 c.321C>G synonymous_variant 0.48 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 0.46 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoA 3878226 c.282C>G synonymous_variant 0.48 rifampicin
rpoA 3878232 c.276G>C synonymous_variant 0.48 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.56 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3878284 p.Glu75Ala missense_variant 0.67 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.53 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.64 rifampicin
rpoA 3878364 c.144A>T synonymous_variant 0.53 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.55 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 0.64 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.71 rifampicin
rpoA 3878388 c.120C>G synonymous_variant 0.75 rifampicin
rpoA 3878391 c.117T>C synonymous_variant 0.73 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.73 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.75 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.71 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.64 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 0.64 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.53 rifampicin
rpoA 3878478 c.30C>G synonymous_variant 0.5 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 0.47 rifampicin
rpoA 3878761 c.-254G>C upstream_gene_variant 0.86 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.8 rifampicin
rpoA 3878785 c.-278T>G upstream_gene_variant 0.71 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.67 rifampicin Uncertain significance
rpoA 3878806 c.-299C>G upstream_gene_variant 0.72 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.72 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 0.64 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 0.57 rifampicin
rpoA 3878836 c.-331_-329delAAGinsTCC upstream_gene_variant 0.5 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.48 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.59 rifampicin Uncertain significance
rpoA 3878917 c.-410G>A upstream_gene_variant 0.53 rifampicin Uncertain significance
rpoA 3878938 c.-431T>C upstream_gene_variant 0.71 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.67 rifampicin Uncertain significance
rpoA 3878968 c.-461T>C upstream_gene_variant 0.73 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.75 rifampicin Uncertain significance
rpoA 3878986 c.-479G>C upstream_gene_variant 0.71 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.68 rifampicin Uncertain significance
rpoA 3879005 c.-499_-498delAAinsCG upstream_gene_variant 0.68 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 0.73 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.7 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.77 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.77 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.63 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.67 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.7 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.78 rifampicin
rpoA 3879178 c.-671T>C upstream_gene_variant 0.75 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 0.5 rifampicin
clpC1 4038509 c.2196C>T synonymous_variant 0.79 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.61 pyrazinamide
clpC1 4038541 c.2164C>T synonymous_variant 0.62 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.53 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.44 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.44 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.44 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.44 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.47 pyrazinamide
clpC1 4038749 c.1956C>G synonymous_variant 0.76 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.85 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.79 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.79 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.81 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.73 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.62 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTG frameshift_variant&synonymous_variant 0.69 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.79 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.73 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.76 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.81 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.82 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.75 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.72 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.72 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.65 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.68 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.65 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.67 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.69 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.67 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.69 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 0.64 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4039229 c.1476C>G synonymous_variant 0.81 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.7 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 0.63 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.63 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 0.44 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.58 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.55 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.6 pyrazinamide
clpC1 4039565 c.1140G>T synonymous_variant 0.6 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.6 pyrazinamide Uncertain significance
clpC1 4039576 p.Ala377Pro missense_variant 0.62 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.62 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.69 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.65 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.65 pyrazinamide
clpC1 4039661 c.1044T>G synonymous_variant 0.67 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.66 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.54 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.5 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.54 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.48 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.5 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.47 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.47 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 0.47 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.47 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.5 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.5 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.59 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 0.68 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.63 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.64 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.67 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.83 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.55 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.62 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.6 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 0.52 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.62 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.61 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.62 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.64 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.65 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.5 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.61 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4040162 c.543G>C synonymous_variant 0.6 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.58 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.68 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.53 pyrazinamide
clpC1 4040207 c.498T>G synonymous_variant 0.43 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 0.38 pyrazinamide
clpC1 4040228 c.477G>T synonymous_variant 0.38 pyrazinamide
clpC1 4040231 c.474C>T synonymous_variant 0.38 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 0.44 pyrazinamide
clpC1 4040246 c.459C>G synonymous_variant 0.53 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.53 pyrazinamide
clpC1 4040477 c.228G>C synonymous_variant 0.55 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.5 pyrazinamide
panD 4043865 c.415_417delGGAinsCG frameshift_variant&missense_variant 0.4 pyrazinamide Uncertain significance
panD 4043872 p.Gly137Val missense_variant 0.4 pyrazinamide Uncertain significance
panD 4043876 p.Leu136Ile missense_variant 0.42 pyrazinamide
panD 4043883 c.399C>T synonymous_variant 0.47 pyrazinamide
panD 4043886 c.396A>G synonymous_variant 0.47 pyrazinamide
panD 4043896 p.Gly129Ala missense_variant 0.47 pyrazinamide
panD 4043903 p.Asn127Asp missense_variant 0.44 pyrazinamide
panD 4043913 c.369T>C synonymous_variant 0.35 pyrazinamide
panD 4043916 c.366A>G synonymous_variant 0.38 pyrazinamide
panD 4044779 c.-500_-498delCTAinsTGC upstream_gene_variant 0.33 pyrazinamide
panD 4044788 c.-507G>C upstream_gene_variant 0.38 pyrazinamide
panD 4044791 c.-510G>C upstream_gene_variant 0.38 pyrazinamide
panD 4044800 c.-519C>G upstream_gene_variant 0.41 pyrazinamide
panD 4044812 c.-531A>C upstream_gene_variant 0.41 pyrazinamide
panD 4045055 c.-774T>G upstream_gene_variant 0.5 pyrazinamide
glpK 4138670 c.1086G>C synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138679 c.1075_1077delATGinsGC frameshift_variant&missense_variant 0.77 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138695 p.Pro354Asp missense_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138721 c.1035G>A synonymous_variant 0.79 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138724 c.1032A>G synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138730 c.1026C>G synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138763 c.993G>A synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138769 c.987G>C synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138774 p.Ser328Ala missense_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138778 c.978C>G synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4239336 c.-527T>C upstream_gene_variant 0.46 ethambutol
embC 4239341 c.-522G>C upstream_gene_variant 0.55 ethambutol
embC 4239344 c.-519G>C upstream_gene_variant 0.55 ethambutol
embC 4239350 c.-513G>C upstream_gene_variant 0.6 ethambutol
embC 4240178 c.316T>C synonymous_variant 0.67 ethambutol
embC 4240183 c.321A>G synonymous_variant 0.67 ethambutol
embC 4240204 c.342T>C synonymous_variant 0.69 ethambutol Not assoc w R - Interim
embC 4240216 c.354T>C synonymous_variant 0.64 ethambutol
embC 4240219 c.357C>G synonymous_variant 0.64 ethambutol
embC 4240222 c.360G>C synonymous_variant 0.64 ethambutol
embC 4240229 c.367_369delCTGinsAC frameshift_variant&missense_variant 0.69 ethambutol
embC 4240232 p.Gln124Val missense_variant 0.69 ethambutol
embC 4240249 p.Asp129Glu missense_variant 0.56 ethambutol
embC 4240258 c.396T>G synonymous_variant 0.56 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.6 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.64 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.64 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.67 ethambutol
embC 4240867 c.1005T>C synonymous_variant 0.56 ethambutol
embC 4240870 c.1008T>C synonymous_variant 0.56 ethambutol
embC 4240873 c.1011C>G synonymous_variant 0.53 ethambutol
embC 4240879 c.1017G>C synonymous_variant 0.53 ethambutol
embC 4240880 p.Ala340Thr missense_variant 0.53 ethambutol Uncertain significance
embC 4240885 c.1023T>C synonymous_variant 0.53 ethambutol
embC 4240897 c.1035C>G synonymous_variant 0.53 ethambutol Not assoc w R
embC 4240898 c.1036_1038delCTAinsTG frameshift_variant&stop_gained 0.53 ethambutol
embC 4240903 c.1041C>G synonymous_variant 0.53 ethambutol
embC 4240911 p.Ala350Val missense_variant 0.57 ethambutol
embC 4240921 c.1059C>G synonymous_variant 0.62 ethambutol
embC 4240924 c.1062C>G synonymous_variant 0.73 ethambutol
embC 4240936 c.1074A>G synonymous_variant 0.58 ethambutol
embC 4241089 c.1227C>G synonymous_variant 0.6 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.58 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.73 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.83 ethambutol Not assoc w R - Interim
embC 4241146 c.1284C>G synonymous_variant 0.88 ethambutol
embC 4241158 c.1296T>C synonymous_variant 0.86 ethambutol
embC 4241161 c.1299C>G synonymous_variant 0.85 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 0.85 ethambutol
embC 4241170 c.1308G>C synonymous_variant 0.77 ethambutol
embC 4241173 c.1311C>T synonymous_variant 0.77 ethambutol
embC 4241203 c.1341T>C synonymous_variant 0.54 ethambutol
embC 4241206 c.1344G>C synonymous_variant 0.54 ethambutol Not assoc w R - Interim
embC 4241218 c.1356G>C synonymous_variant 0.54 ethambutol
embC 4241479 c.1617C>G synonymous_variant 0.54 ethambutol
embC 4241480 c.1618T>C synonymous_variant 0.54 ethambutol
embC 4241488 c.1626G>C synonymous_variant 0.5 ethambutol
embC 4241496 p.Ala545Gly missense_variant 0.43 ethambutol
embC 4241500 c.1638A>C synonymous_variant 0.43 ethambutol
embC 4241501 p.Ser547Thr missense_variant 0.43 ethambutol
embC 4241506 c.1644G>C synonymous_variant 0.43 ethambutol
embC 4241518 c.1656A>G synonymous_variant 0.43 ethambutol
embC 4241521 c.1659T>C synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embC 4241530 c.1668C>G synonymous_variant 0.53 ethambutol
embC 4242764 p.Val968Leu missense_variant 0.47 ethambutol
embA 4242772 c.-461G>C upstream_gene_variant 0.53 ethambutol
embC 4242779 p.Asn973Asp missense_variant 0.53 ethambutol
embA 4244507 c.1275G>T synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embA 4244508 c.1276T>C synonymous_variant 0.5 ethambutol
embA 4244516 c.1284G>C synonymous_variant 0.53 ethambutol
embA 4244517 p.Leu429Val missense_variant 0.5 ethambutol
embA 4244523 p.Pro431Ala missense_variant 0.5 ethambutol
embA 4244534 c.1302T>C synonymous_variant 0.5 ethambutol
embA 4244537 c.1305T>G synonymous_variant 0.53 ethambutol
embA 4244543 c.1311C>G synonymous_variant 0.53 ethambutol
embA 4244547 p.Ile439Val missense_variant 0.6 ethambutol
embA 4245101 c.1869G>C synonymous_variant 0.55 ethambutol
embA 4245137 c.1905T>C synonymous_variant 0.6 ethambutol
embA 4245146 c.1914G>A synonymous_variant 0.6 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.63 ethambutol
embA 4245153 p.Ile641Val missense_variant 0.67 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.72 ethambutol
embA 4245189 c.1957C>T synonymous_variant 0.68 ethambutol
embA 4245198 p.Leu656Ile missense_variant 0.58 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.5 ethambutol
embB 4245725 c.-789A>G upstream_gene_variant 0.6 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 0.6 ethambutol
embB 4245737 c.-777A>C upstream_gene_variant 0.64 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 0.75 ethambutol
embA 4246080 c.2848_2850delCCTinsTC frameshift_variant&missense_variant 0.47 ethambutol Uncertain significance
embA 4246088 c.2856A>G synonymous_variant 0.56 ethambutol Not assoc w R
embB 4246097 c.-417C>G upstream_gene_variant 0.53 ethambutol
embA 4246103 c.2871C>G synonymous_variant 0.47 ethambutol Not assoc w R - Interim
embB 4246109 c.-405C>G upstream_gene_variant 0.37 ethambutol
embA 4246264 p.His1011Arg missense_variant 0.44 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 0.44 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 0.44 ethambutol
embA 4246308 p.Thr1026Ala missense_variant 0.44 ethambutol
embB 4246316 c.-198T>G upstream_gene_variant 0.48 ethambutol
embB 4246319 c.-195G>C upstream_gene_variant 0.53 ethambutol
embA 4246329 p.Thr1033Ala missense_variant 0.6 ethambutol
embB 4246349 c.-165C>G upstream_gene_variant 0.72 ethambutol
embA 4246359 c.3127_3129delGCCinsTG frameshift_variant&missense_variant 0.71 ethambutol Uncertain significance
embB 4246367 c.-147C>T upstream_gene_variant 0.62 ethambutol
embB 4246373 c.-141T>C upstream_gene_variant 0.67 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 0.67 ethambutol
embA 4246379 c.3147C>T synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embB 4247446 c.933C>T synonymous_variant 0.57 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.71 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.73 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.74 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.71 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.7 ethambutol
embB 4247539 c.1026T>C synonymous_variant 0.67 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.5 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.45 ethambutol
embB 4247572 c.1059A>G synonymous_variant 0.45 ethambutol
embB 4247729 p.Gly406Thr missense_variant 1.0 ethambutol
embB 4247761 c.1248T>C synonymous_variant 0.6 ethambutol
embB 4247905 c.1392G>C synonymous_variant 0.53 ethambutol Not assoc w R - Interim
embB 4247909 c.1396T>C synonymous_variant 0.5 ethambutol
embB 4247914 c.1401G>C synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embB 4247932 c.1419C>G synonymous_variant 0.5 ethambutol
embB 4247940 p.Leu476Trp missense_variant 0.56 ethambutol
embB 4247945 c.1432T>C synonymous_variant 0.47 ethambutol
embB 4247951 p.Ser480Ala missense_variant 0.47 ethambutol
embB 4247956 c.1443G>C synonymous_variant 0.47 ethambutol Not assoc w R - Interim
embB 4248035 p.Val508Ile missense_variant 0.69 ethambutol
embB 4248040 c.1527C>G synonymous_variant 0.69 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.69 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.69 ethambutol
embB 4248070 c.1557T>C synonymous_variant 0.71 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.53 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.53 ethambutol
embB 4248143 c.1630T>C synonymous_variant 0.53 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.5 ethambutol Not assoc w R - Interim
embB 4248172 c.1659G>C synonymous_variant 0.53 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.53 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.53 ethambutol
embB 4248205 c.1692C>G synonymous_variant 0.5 ethambutol
embB 4248206 c.1693_1695delAGCinsGT frameshift_variant&missense_variant 0.5 ethambutol
embB 4248220 c.1707A>C synonymous_variant 0.55 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.59 ethambutol
embB 4248316 c.1803C>G synonymous_variant 0.55 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.56 ethambutol
embB 4248373 c.1860C>G synonymous_variant 0.45 ethambutol
embB 4248382 c.1869C>G synonymous_variant 0.44 ethambutol
embB 4248386 c.1873C>A synonymous_variant 0.35 ethambutol
embB 4249417 c.2904A>G synonymous_variant 0.77 ethambutol
embB 4249423 p.Asp970Glu missense_variant 0.69 ethambutol Uncertain significance
embB 4249424 p.Leu971Met missense_variant 0.69 ethambutol
embB 4249429 c.2916C>T synonymous_variant 0.73 ethambutol
embB 4249432 c.2919A>G synonymous_variant 0.79 ethambutol
embB 4249441 c.2928A>G synonymous_variant 0.8 ethambutol Not assoc w R - Interim
embB 4249444 c.2931T>C synonymous_variant 0.8 ethambutol
embB 4249469 p.Leu986Met missense_variant 0.76 ethambutol
embB 4249486 c.2973T>G synonymous_variant 0.73 ethambutol
embB 4249498 c.2985G>C synonymous_variant 0.67 ethambutol
embB 4249521 p.Ala1003Val missense_variant 0.65 ethambutol
embB 4249525 c.3012T>C synonymous_variant 0.62 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.58 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 0.58 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 0.58 ethambutol
embB 4249543 c.3030G>C synonymous_variant 0.58 ethambutol
embB 4249546 c.3033G>A synonymous_variant 0.55 ethambutol
aftB 4268994 c.-158T>G upstream_gene_variant 0.39 ethambutol
ubiA 4268999 c.835C>T synonymous_variant 0.42 ethambutol Not assoc w R - Interim
aftB 4269006 c.-170T>C upstream_gene_variant 0.45 ethambutol
aftB 4269012 c.-176G>C upstream_gene_variant 0.41 ethambutol
ubiA 4269027 c.807C>T synonymous_variant 0.41 ethambutol Not assoc w R - Interim
aftB 4269033 c.-197T>C upstream_gene_variant 0.47 ethambutol
aftB 4269036 c.-200C>G upstream_gene_variant 0.47 ethambutol
aftB 4269042 c.-206G>C upstream_gene_variant 0.45 ethambutol
aftB 4269201 c.-365A>G upstream_gene_variant 0.8 ethambutol
aftB 4269206 c.-370C>T upstream_gene_variant 0.73 ethambutol
ubiA 4269220 p.Ala205Lys missense_variant 0.62 ethambutol
ubiA 4269222 c.612T>C synonymous_variant 0.62 ethambutol Not assoc w R - Interim
aftB 4269242 c.-406C>T upstream_gene_variant 0.47 ethambutol
ubiA 4269243 p.His197Gln missense_variant 0.47 ethambutol
aftB 4269249 c.-413G>A upstream_gene_variant 0.44 ethambutol
aftB 4269258 c.-422C>T upstream_gene_variant 0.44 ethambutol