Run ID: SRR13583478
Sample name:
Date: 2024-04-16T08:16:19.353537
Number of reads: 1042058
Percentage reads mapped: 64.41
Median coverage: 31.0
Strain: lineage4.3.4.1
Spoligotype:
Drug-resistance: HR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4.3 | Euro-American (LAM) | None | 0.88 |
lineage4.3.4.1 | Euro-American (LAM) | RD174 | 0.88 |
lineage4 | Euro-American | None | 0.98 |
lineage4.3.4 | Euro-American (LAM) | RD174 | 0.89 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | katG | p.Ile335Thr | Mutation from literature | |
ethambutol | ||||
pyrazinamide | ||||
streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | fgd1 | c.718_720delGAGinsAA | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
c.730_732delAACinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
fbiC | c.604_606delTCGinsGC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
c.859_861delATCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.913_915delGCCinsAG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.1018_1020delGGCinsCT | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.1078_1080delTTGinsCC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
fgd1 | 491500 | c.718_720delGAGinsAA | frameshift_variant&missense_variant | 0.31 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 491512 | c.730_732delAACinsGG | frameshift_variant&missense_variant | 0.33 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303534 | c.604_606delTCGinsGC | frameshift_variant&missense_variant | 0.39 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303789 | c.859_861delATCinsGG | frameshift_variant&missense_variant | 0.26 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303843 | c.913_915delGCCinsAG | frameshift_variant&missense_variant | 0.2 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303948 | c.1018_1020delGGCinsCT | frameshift_variant&missense_variant | 0.34 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1304008 | c.1078_1080delTTGinsCC | frameshift_variant&missense_variant | 0.42 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.53 | streptomycin | Uncertain significance | Mutation from literature |
katG | 2155108 | p.Ile335Thr | missense_variant | 0.19 | isoniazid | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 690 | c.690G>C | synonymous_variant | 0.39 | isoniazid | |
dnaA | 693 | c.693A>G | synonymous_variant | 0.39 | isoniazid | Not assoc w R - Interim |
dnaA | 705 | c.705A>G | synonymous_variant | 0.45 | isoniazid | |
dnaA | 708 | c.708T>C | synonymous_variant | 0.45 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 0.36 | isoniazid | Not assoc w R - Interim |
dnaA | 750 | c.750C>G | synonymous_variant | 0.38 | isoniazid | |
dnaA | 756 | c.756T>C | synonymous_variant | 0.4 | isoniazid | |
dnaA | 771 | c.771A>C | synonymous_variant | 0.38 | isoniazid | |
dnaA | 777 | c.777A>G | synonymous_variant | 0.39 | isoniazid | |
dnaA | 786 | c.786C>T | synonymous_variant | 0.37 | isoniazid | |
dnaA | 795 | c.795A>C | synonymous_variant | 0.38 | isoniazid | Not assoc w R - Interim |
dnaA | 805 | c.805T>C | synonymous_variant | 0.41 | isoniazid | |
dnaA | 822 | c.822A>G | synonymous_variant | 0.41 | isoniazid | |
dnaA | 828 | c.828T>C | synonymous_variant | 0.38 | isoniazid | Not assoc w R - Interim |
dnaA | 831 | c.831A>G | synonymous_variant | 0.34 | isoniazid | |
dnaA | 840 | c.840G>A | synonymous_variant | 0.33 | isoniazid | |
dnaA | 846 | c.846T>C | synonymous_variant | 0.34 | isoniazid | |
dnaA | 849 | c.849A>G | synonymous_variant | 0.34 | isoniazid | |
dnaA | 852 | c.852G>A | synonymous_variant | 0.34 | isoniazid | Not assoc w R - Interim |
dnaA | 877 | c.877T>C | synonymous_variant | 0.32 | isoniazid | |
dnaA | 882 | c.882C>T | synonymous_variant | 0.33 | isoniazid | |
dnaA | 885 | c.885T>C | synonymous_variant | 0.31 | isoniazid | |
dnaA | 897 | c.897A>G | synonymous_variant | 0.27 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 0.19 | isoniazid | |
dnaA | 927 | c.927G>A | synonymous_variant | 0.18 | isoniazid | |
dnaA | 1014 | c.1014C>G | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1038 | c.1038A>T | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1068 | c.1068T>C | synonymous_variant | 0.37 | isoniazid | |
dnaA | 1092 | c.1092T>C | synonymous_variant | 0.39 | isoniazid | Not assoc w R - Interim |
dnaA | 1098 | c.1098A>G | synonymous_variant | 0.4 | isoniazid | |
dnaA | 1104 | c.1104T>C | synonymous_variant | 0.4 | isoniazid | |
dnaA | 1110 | c.1110T>C | synonymous_variant | 0.38 | isoniazid | |
dnaA | 1113 | c.1113A>G | synonymous_variant | 0.38 | isoniazid | |
dnaA | 1122 | c.1122C>T | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1125 | c.1125G>C | synonymous_variant | 0.3 | isoniazid | |
dnaA | 1137 | c.1137C>G | synonymous_variant | 0.3 | isoniazid | |
dnaA | 1164 | c.1164A>C | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1167 | c.1167A>G | synonymous_variant | 0.22 | isoniazid | Not assoc w R - Interim |
dnaA | 1185 | c.1185C>G | synonymous_variant | 0.27 | isoniazid | Not assoc w R - Interim |
dnaA | 1188 | c.1188G>A | synonymous_variant | 0.26 | isoniazid | |
gyrB | 6238 | c.999G>A | synonymous_variant | 0.69 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.69 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 0.61 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.68 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6283 | c.1044C>T | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>T | synonymous_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6298 | c.1059C>G | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.58 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 0.59 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 6361 | c.-941G>A | upstream_gene_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6376 | c.-926G>A | upstream_gene_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6379 | c.-923C>G | upstream_gene_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6382 | c.-920A>G | upstream_gene_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6388 | c.-914T>C | upstream_gene_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6403 | c.-899T>C | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6412 | c.-890G>A | upstream_gene_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6751 | c.-551G>C | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6775 | c.1536G>C | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6794 | p.Ile519Leu | missense_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6797 | p.Gly520Thr | missense_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6811 | c.1572C>T | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6841 | c.1602T>C | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6856 | c.1617T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6859 | c.1620T>C | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6862 | c.1623C>G | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6878 | c.1639T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6881 | c.1642T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6889 | c.-413G>T | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6904 | c.-398C>G | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6913 | c.1674C>T | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6919 | c.1680T>C | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6934 | c.-368A>G | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6949 | c.-353A>G | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6950 | c.1711_1713delCTCinsTG | frameshift_variant&missense_variant | 0.29 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrA | 6973 | c.-329G>C | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6982 | c.-320A>C | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6988 | c.-314C>A | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7000 | c.-302C>A | upstream_gene_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7006 | c.-296T>C | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7007 | c.-295C>T | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7018 | c.-284G>C | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7021 | c.-281G>C | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7023 | p.Leu595Gln | missense_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7030 | c.-272C>G | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7033 | c.-269G>C | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7051 | p.Glu604Asp | missense_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 8189 | c.888G>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8198 | c.897T>C | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8330 | c.1029C>G | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8401 | p.Asp367Ala | missense_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8655 | p.Ile452Val | missense_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8684 | c.1383G>A | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8696 | c.1395G>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8699 | c.1398A>G | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8714 | c.1413A>G | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8729 | c.1428T>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8730 | c.1429_1431delGGGinsCC | frameshift_variant&missense_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8740 | p.Arg480His | missense_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8747 | c.1446A>G | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8750 | c.1449C>G | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8751 | p.Ala484Ser | missense_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8756 | c.1455A>G | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8762 | c.1461G>C | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8767 | p.Arg489Lys | missense_variant | 0.37 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8780 | c.1479C>T | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8786 | c.1485T>C | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8810 | c.1509A>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8818 | p.Ser506Asn | missense_variant | 0.35 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8828 | c.1527T>C | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8837 | c.1536C>G | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8852 | c.1551T>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8858 | c.1557T>C | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9191 | c.1890G>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9197 | c.1896G>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9242 | c.1941A>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9299 | c.1998G>T | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
fgd1 | 491121 | c.339A>G | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491130 | c.348C>G | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491283 | p.Asp167Glu | missense_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491286 | c.504G>T | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491289 | c.507C>G | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491292 | c.510G>C | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491295 | c.513C>G | synonymous_variant | 0.33 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491296 | p.Val172Ile | missense_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491302 | p.Ile174Val | missense_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491307 | c.525C>G | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491313 | c.531C>G | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491340 | c.558C>G | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491349 | c.567T>C | synonymous_variant | 0.34 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491364 | c.582T>C | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491367 | c.585G>C | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491370 | c.588C>G | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491472 | c.690A>G | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491487 | c.705C>T | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491496 | c.714C>T | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491499 | c.717G>C | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491508 | c.726A>G | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491509 | c.727T>C | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491526 | c.744T>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491535 | c.753G>C | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491541 | c.759G>A | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491542 | c.760T>C | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491547 | c.765A>C | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491550 | c.768T>C | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491583 | c.801G>A | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491601 | c.819T>C | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491610 | c.828A>G | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
mshA | 574650 | c.-698A>C | upstream_gene_variant | 0.19 | ethionamide | |
isoniazid | ||||||
mshA | 574655 | c.-693C>G | upstream_gene_variant | 0.18 | ethionamide | |
isoniazid | ||||||
mshA | 574671 | c.-677_-675delGCAinsCTG | upstream_gene_variant | 0.22 | ethionamide | |
isoniazid | ||||||
mshA | 574676 | c.-672G>C | upstream_gene_variant | 0.23 | ethionamide | |
isoniazid | ||||||
mshA | 574683 | c.-665T>C | upstream_gene_variant | 0.23 | ethionamide | |
isoniazid | Uncertain significance | |||||
mshA | 574688 | c.-660G>C | upstream_gene_variant | 0.24 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
mshA | 574694 | c.-654C>G | upstream_gene_variant | 0.26 | ethionamide | |
isoniazid | ||||||
mshA | 574718 | c.-630A>C | upstream_gene_variant | 0.24 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
mshA | 574731 | c.-617A>G | upstream_gene_variant | 0.23 | ethionamide | |
isoniazid | ||||||
mshA | 574739 | c.-609T>C | upstream_gene_variant | 0.27 | ethionamide | |
isoniazid | ||||||
mshA | 575593 | c.246G>C | synonymous_variant | 0.21 | ethionamide | |
isoniazid | ||||||
mshA | 575617 | c.270C>G | synonymous_variant | 0.28 | ethionamide | |
isoniazid | ||||||
mshA | 575623 | c.276C>G | synonymous_variant | 0.26 | ethionamide | |
isoniazid | ||||||
mshA | 575629 | c.282A>G | synonymous_variant | 0.28 | ethionamide | |
isoniazid | ||||||
mshA | 575632 | c.285G>C | synonymous_variant | 0.3 | ethionamide | |
isoniazid | ||||||
mshA | 575635 | c.288A>G | synonymous_variant | 0.3 | ethionamide | |
isoniazid | ||||||
mshA | 575638 | c.291T>C | synonymous_variant | 0.3 | ethionamide | |
isoniazid | ||||||
mshA | 575647 | c.300G>C | synonymous_variant | 0.3 | ethionamide | |
isoniazid | ||||||
mshA | 575649 | p.Val101Ala | missense_variant | 0.3 | ethionamide | |
isoniazid | ||||||
mshA | 575659 | c.312A>G | synonymous_variant | 0.25 | ethionamide | |
isoniazid | ||||||
mshA | 575662 | c.315C>G | synonymous_variant | 0.24 | ethionamide | |
isoniazid | ||||||
mshA | 575692 | c.345G>C | synonymous_variant | 0.19 | ethionamide | |
isoniazid | ||||||
mshA | 575695 | c.348C>G | synonymous_variant | 0.19 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575701 | c.354G>A | synonymous_variant | 0.19 | ethionamide | |
isoniazid | ||||||
mshA | 575704 | c.357T>C | synonymous_variant | 0.2 | ethionamide | |
isoniazid | ||||||
mshA | 575713 | c.366G>A | synonymous_variant | 0.18 | ethionamide | |
isoniazid | ||||||
mshA | 575779 | c.432A>G | synonymous_variant | 0.2 | ethionamide | |
isoniazid | ||||||
mshA | 575803 | c.456C>T | synonymous_variant | 0.19 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575812 | c.465C>T | synonymous_variant | 0.18 | ethionamide | |
isoniazid | ||||||
ccsA | 619507 | c.-384A>G | upstream_gene_variant | 0.29 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619528 | c.-363C>G | upstream_gene_variant | 0.31 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619531 | c.-360T>C | upstream_gene_variant | 0.31 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619535 | c.-356_-354delCAAinsGCG | upstream_gene_variant | 0.3 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619543 | c.-348C>G | upstream_gene_variant | 0.31 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619552 | c.-339A>G | upstream_gene_variant | 0.33 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619555 | c.-336C>G | upstream_gene_variant | 0.33 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619558 | c.-333G>T | upstream_gene_variant | 0.35 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619570 | c.-321G>C | upstream_gene_variant | 0.36 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619574 | c.-317G>A | upstream_gene_variant | 0.37 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619579 | c.-312G>C | upstream_gene_variant | 0.38 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619584 | c.-307A>T | upstream_gene_variant | 0.4 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619591 | c.-300G>T | upstream_gene_variant | 0.4 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619606 | c.-285C>T | upstream_gene_variant | 0.35 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619609 | c.-282G>C | upstream_gene_variant | 0.35 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619634 | c.-257T>A | upstream_gene_variant | 0.32 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619645 | c.-246G>C | upstream_gene_variant | 0.25 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619668 | c.-223_-222delCGinsGC | upstream_gene_variant | 0.21 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619672 | c.-219A>T | upstream_gene_variant | 0.18 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620659 | p.Arg257Ser | missense_variant | 0.18 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620664 | c.774C>T | synonymous_variant | 0.19 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620682 | c.792G>A | synonymous_variant | 0.24 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620688 | c.798G>C | synonymous_variant | 0.23 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620710 | c.820_822delGTGinsAT | frameshift_variant&missense_variant | 0.22 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620718 | c.828G>C | synonymous_variant | 0.22 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620721 | c.831G>C | synonymous_variant | 0.21 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620733 | c.843G>C | synonymous_variant | 0.2 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620734 | c.844C>A | synonymous_variant | 0.2 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620739 | c.849A>G | synonymous_variant | 0.2 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620748 | c.858T>A | synonymous_variant | 0.2 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620778 | c.888T>C | synonymous_variant | 0.21 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620784 | c.894C>G | synonymous_variant | 0.22 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620790 | c.900C>T | synonymous_variant | 0.2 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620796 | c.906C>G | synonymous_variant | 0.19 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
Rv0565c | 656924 | p.Ile183Val | missense_variant | 0.23 | ethionamide | |
Rv0565c | 656935 | p.Thr179Asp | missense_variant | 0.21 | ethionamide | |
Rv0565c | 656946 | c.525T>C | synonymous_variant | 0.22 | ethionamide | |
Rv0565c | 656952 | c.519A>G | synonymous_variant | 0.25 | ethionamide | |
Rv0565c | 656967 | c.504T>C | synonymous_variant | 0.26 | ethionamide | |
Rv0565c | 656973 | c.498A>G | synonymous_variant | 0.27 | ethionamide | |
Rv0565c | 656978 | p.Ala165Thr | missense_variant | 0.29 | ethionamide | |
Rv0565c | 656982 | p.Gly163Thr | missense_variant | 0.29 | ethionamide | |
Rv0565c | 656985 | c.486T>C | synonymous_variant | 0.27 | ethionamide | |
Rv0565c | 656990 | p.Lys161Glu | missense_variant | 0.29 | ethionamide | |
Rv0565c | 657000 | p.Gly157Pro | missense_variant | 0.3 | ethionamide | |
Rv0565c | 657027 | c.444T>C | synonymous_variant | 0.32 | ethionamide | |
Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 0.25 | ethionamide | |
Rv0565c | 657261 | c.210C>G | synonymous_variant | 0.26 | ethionamide | |
Rv0565c | 657264 | c.207T>C | synonymous_variant | 0.25 | ethionamide | |
Rv0565c | 657267 | c.204G>C | synonymous_variant | 0.24 | ethionamide | |
Rv0565c | 657300 | c.171C>G | synonymous_variant | 0.41 | ethionamide | |
Rv0565c | 657318 | c.153T>C | synonymous_variant | 0.35 | ethionamide | |
Rv0565c | 657324 | c.147C>G | synonymous_variant | 0.36 | ethionamide | |
Rv0565c | 657327 | c.144C>G | synonymous_variant | 0.36 | ethionamide | |
Rv0565c | 657337 | p.Arg45Gln | missense_variant | 0.38 | ethionamide | Uncertain significance |
Rv0565c | 657340 | p.Ala44Glu | missense_variant | 0.4 | ethionamide | |
Rv0565c | 657342 | c.129T>C | synonymous_variant | 0.4 | ethionamide | |
Rv0565c | 657347 | c.124A>C | synonymous_variant | 0.4 | ethionamide | |
Rv0565c | 657348 | c.123A>G | synonymous_variant | 0.42 | ethionamide | |
Rv0565c | 657354 | p.Ile39Met | missense_variant | 0.44 | ethionamide | |
Rv0565c | 657363 | c.108C>G | synonymous_variant | 0.45 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAC | upstream_gene_variant | 0.25 | ethionamide | |
Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 0.2 | ethionamide | |
hadA | 732295 | c.366G>C | synonymous_variant | 0.23 | isoniazid | |
hadA | 732304 | c.375C>T | synonymous_variant | 0.23 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 0.23 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.24 | isoniazid | |
hadA | 732319 | c.390G>A | synonymous_variant | 0.23 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.23 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 0.32 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 0.37 | isoniazid | |
hadA | 732346 | c.417T>C | synonymous_variant | 0.41 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.46 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.45 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.46 | isoniazid | |
nusG | 734370 | c.117A>G | synonymous_variant | 0.3 | rifampicin | |
nusG | 734376 | c.123G>A | synonymous_variant | 0.36 | rifampicin | |
nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 0.47 | rifampicin | |
nusG | 734421 | c.168A>G | synonymous_variant | 0.47 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 0.48 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 0.54 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.54 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.55 | rifampicin | |
nusG | 734460 | c.207G>T | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
nusG | 734472 | c.219T>C | synonymous_variant | 0.6 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
nusG | 734499 | c.246G>C | synonymous_variant | 0.6 | rifampicin | |
nusG | 734532 | c.279A>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
nusG | 734556 | c.303C>T | synonymous_variant | 0.39 | rifampicin | |
nusG | 734559 | c.306T>C | synonymous_variant | 0.38 | rifampicin | |
nusG | 734571 | c.318C>G | synonymous_variant | 0.39 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
nusG | 734589 | c.336G>C | synonymous_variant | 0.37 | rifampicin | |
nusG | 734596 | c.343T>C | synonymous_variant | 0.38 | rifampicin | |
nusG | 734625 | c.372T>C | synonymous_variant | 0.29 | rifampicin | |
nusG | 734631 | c.378G>C | synonymous_variant | 0.27 | rifampicin | |
nusG | 734634 | c.381G>C | synonymous_variant | 0.26 | rifampicin | |
nusG | 734637 | c.384G>C | synonymous_variant | 0.26 | rifampicin | |
nusG | 734643 | c.390G>C | synonymous_variant | 0.26 | rifampicin | |
nusG | 734652 | c.399T>C | synonymous_variant | 0.24 | rifampicin | |
nusG | 734658 | c.405A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R |
nusG | 734661 | c.408A>C | synonymous_variant | 0.22 | rifampicin | |
nusG | 734664 | c.411T>G | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760091 | c.285G>A | synonymous_variant | 0.26 | rifampicin | |
rpoB | 760101 | c.295T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 760112 | c.306T>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 760118 | c.312T>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.41 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.44 | rifampicin | |
rpoB | 760145 | c.339C>G | synonymous_variant | 0.44 | rifampicin | |
rpoB | 760181 | c.375T>G | synonymous_variant | 0.49 | rifampicin | |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 760298 | c.492G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.41 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.42 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.41 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 760358 | c.552C>G | synonymous_variant | 0.49 | rifampicin | |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.47 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.44 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.44 | rifampicin | |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.41 | rifampicin | |
rpoB | 760412 | c.606C>G | synonymous_variant | 0.41 | rifampicin | |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 760442 | c.636G>A | synonymous_variant | 0.43 | rifampicin | |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 760511 | c.705G>C | synonymous_variant | 0.31 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760649 | c.843G>C | synonymous_variant | 0.34 | rifampicin | |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.31 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760755 | p.His317Asn | missense_variant | 0.19 | rifampicin | |
rpoB | 760793 | c.987A>G | synonymous_variant | 0.2 | rifampicin | |
rpoB | 760820 | c.1014T>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 760826 | c.1020C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 760830 | c.1024T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.41 | rifampicin | |
rpoB | 761006 | c.1200C>T | synonymous_variant | 0.46 | rifampicin | |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.46 | rifampicin | |
rpoB | 761129 | c.1323G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 761207 | c.1401C>T | synonymous_variant | 0.43 | rifampicin | |
rpoB | 761213 | c.1407G>C | synonymous_variant | 0.42 | rifampicin | |
rpoB | 761234 | c.1428G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 761286 | c.1480C>T | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761531 | c.1725C>G | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.33 | rifampicin | |
rpoB | 761612 | c.1806G>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 761672 | c.1866C>G | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761675 | c.1869G>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 761690 | c.1884G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761720 | c.1914_1916delCGAinsGG | frameshift_variant&synonymous_variant | 0.24 | rifampicin | |
rpoB | 761727 | p.Ser641Gly | missense_variant | 0.24 | rifampicin | |
rpoB | 761730 | c.1924_1926delGGCinsTGGG | frameshift_variant&missense_variant | 0.25 | rifampicin | |
rpoB | 761735 | c.1929C>G | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761747 | c.1941G>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.3 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.31 | rifampicin | |
rpoB | 761789 | c.1983G>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.26 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761815 | p.Ala670Glu | missense_variant | 0.21 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761858 | c.2052G>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761873 | c.2067A>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.25 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.25 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 761999 | c.2193G>C | synonymous_variant | 0.42 | rifampicin | |
rpoB | 762008 | c.2202C>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.38 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.37 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.39 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.35 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.37 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 762206 | c.2400C>G | synonymous_variant | 0.37 | rifampicin | |
rpoB | 762212 | c.2406G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.38 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.38 | rifampicin | |
rpoB | 762260 | c.2454C>T | synonymous_variant | 0.38 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 762323 | c.2517C>G | synonymous_variant | 0.39 | rifampicin | |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.41 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.4 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.4 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 762380 | c.-990T>C | upstream_gene_variant | 0.33 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.36 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.36 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.39 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 762419 | c.-951C>G | upstream_gene_variant | 0.37 | rifampicin | |
rpoC | 762434 | c.-936T>C | upstream_gene_variant | 0.34 | rifampicin | |
rpoB | 762449 | c.2643C>A | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 762467 | c.-903C>T | upstream_gene_variant | 0.31 | rifampicin | |
rpoB | 762488 | c.2682G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762489 | p.Val895Gln | missense_variant | 0.28 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.24 | rifampicin | |
rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 0.27 | rifampicin | |
rpoC | 762521 | c.-849C>G | upstream_gene_variant | 0.26 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.24 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.25 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.25 | rifampicin | |
rpoC | 762551 | c.-819C>G | upstream_gene_variant | 0.24 | rifampicin | |
rpoC | 762554 | c.-816G>A | upstream_gene_variant | 0.24 | rifampicin | |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 762860 | c.3054G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762962 | c.3156C>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 762971 | c.3165G>A | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.35 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 763136 | c.3330C>T | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.43 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.44 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763202 | c.-168A>G | upstream_gene_variant | 0.23 | rifampicin | |
rpoC | 763205 | c.-165G>C | upstream_gene_variant | 0.21 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 0.21 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.19 | rifampicin | |
rpoB | 763227 | c.3421C>T | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 763402 | c.33C>A | synonymous_variant | 0.31 | rifampicin | |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.35 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.39 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.38 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 763774 | c.405G>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 763792 | p.Glu141Asp | missense_variant | 0.35 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 763816 | c.447C>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 0.33 | rifampicin | |
rpoC | 763853 | c.484_486delGTCinsAT | frameshift_variant&missense_variant | 0.35 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.3 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.29 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 763900 | c.531G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 763945 | c.576T>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 763951 | c.582G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 763972 | c.603C>T | synonymous_variant | 0.36 | rifampicin | |
rpoC | 763987 | c.618C>T | synonymous_variant | 0.4 | rifampicin | |
rpoC | 763991 | c.622_624delATCinsCG | frameshift_variant&missense_variant | 0.41 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 764002 | c.633C>G | synonymous_variant | 0.41 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 764024 | c.655_657delTTGinsCC | frameshift_variant&missense_variant | 0.46 | rifampicin | |
rpoC | 764032 | p.Asp221Glu | missense_variant | 0.46 | rifampicin | |
rpoC | 764040 | p.Ser224Thr | missense_variant | 0.43 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 764059 | c.690G>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 764215 | c.846A>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764272 | c.903G>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764290 | c.921C>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764293 | c.924G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 764353 | c.984G>T | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 764359 | c.990C>G | synonymous_variant | 0.39 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764387 | c.1018T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036_1038delAGGinsCC | frameshift_variant&missense_variant | 0.31 | rifampicin | |
rpoC | 764419 | c.1050C>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764428 | c.1059G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764489 | c.1120C>T | synonymous_variant | 0.23 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764506 | c.1137C>T | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764510 | c.1141C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764524 | c.1155C>T | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 764576 | c.1207_1208delTCinsAG | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764593 | c.1224C>T | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764626 | c.1257C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764632 | c.1263T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764665 | c.1296C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764716 | c.1347G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764797 | c.1428G>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 764803 | c.1434C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764935 | c.1566T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R |
rpoC | 765343 | c.1974G>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 765352 | c.1983G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 765370 | c.2001G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 765371 | c.2002C>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.3 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 0.28 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765451 | c.2082C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 765452 | c.2083_2085delGCCinsTG | frameshift_variant&missense_variant | 0.23 | rifampicin | |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 765580 | c.2211G>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.38 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 765628 | c.2259G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.38 | rifampicin | |
rpoC | 765658 | c.2289C>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>T | synonymous_variant | 0.52 | rifampicin | |
rpoC | 765751 | c.2382C>G | synonymous_variant | 0.45 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 0.45 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.4 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.43 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.44 | rifampicin | |
rpoC | 765811 | c.2442T>G | synonymous_variant | 0.48 | rifampicin | |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.44 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.47 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 765979 | c.2610C>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>T | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 766009 | c.2640G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.39 | rifampicin | |
rpoC | 766054 | c.2685C>G | synonymous_variant | 0.39 | rifampicin | |
rpoC | 766061 | p.Val898Ile | missense_variant | 0.44 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.33 | rifampicin | |
rpoC | 766105 | c.2736C>T | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766135 | c.2766G>A | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 766141 | c.2772C>T | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766142 | c.2773C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 766148 | p.Thr927Ala | missense_variant | 0.21 | rifampicin | Uncertain significance |
rpoC | 766390 | c.3021C>T | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766408 | c.3039C>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.42 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 766459 | c.3090G>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766484 | c.3115_3117delGTAinsAC | frameshift_variant&missense_variant | 0.32 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766495 | c.3126C>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766531 | c.3162G>T | synonymous_variant | 0.47 | rifampicin | |
rpoC | 766540 | p.Asp1057Glu | missense_variant | 0.43 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 0.43 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766582 | c.3213C>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 766583 | c.3214_3216delGGTinsAC | frameshift_variant&missense_variant | 0.29 | rifampicin | |
rpoC | 766591 | c.3222A>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766597 | c.3228C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.37 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.39 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766673 | p.Gly1102Asn | missense_variant | 0.35 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.47 | rifampicin | |
rpoC | 766801 | c.3432C>G | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.49 | rifampicin | |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 766903 | c.3534C>T | synonymous_variant | 0.53 | rifampicin | |
rpoC | 766918 | c.3549C>T | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.51 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.51 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 767032 | c.3663G>T | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 767035 | c.3666G>T | synonymous_variant | 0.47 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.54 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.44 | rifampicin | |
rpoC | 767158 | c.3789T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 767167 | c.3798C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.37 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 767200 | c.3831G>A | synonymous_variant | 0.28 | rifampicin | |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 767212 | c.3843G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 777133 | p.Val450Ile | missense_variant | 0.25 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777158 | c.1323C>G | synonymous_variant | 0.31 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777164 | c.1317C>G | synonymous_variant | 0.3 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777170 | c.1311T>C | synonymous_variant | 0.3 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777173 | c.1308C>G | synonymous_variant | 0.3 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777176 | p.Glu435Asp | missense_variant | 0.29 | clofazimine | |
bedaquiline | ||||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.27 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.25 | streptomycin | |
rpsL | 781700 | c.141G>C | synonymous_variant | 0.32 | streptomycin | |
rpsL | 781703 | c.144G>T | synonymous_variant | 0.29 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.28 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.29 | streptomycin | |
rpsL | 781742 | c.183C>T | synonymous_variant | 0.31 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.32 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.36 | streptomycin | |
rpsL | 781769 | c.210G>A | synonymous_variant | 0.34 | streptomycin | |
rpsL | 781772 | c.213C>T | synonymous_variant | 0.34 | streptomycin | Not assoc w R - Interim |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.37 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 0.37 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.36 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 0.34 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.34 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.3 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.31 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.29 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.27 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.3 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.31 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.36 | streptomycin | Uncertain significance |
rplC | 800516 | c.-293G>T | upstream_gene_variant | 0.18 | linezolid | |
rplC | 800537 | c.-272C>T | upstream_gene_variant | 0.3 | linezolid | |
rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.3 | linezolid | |
rplC | 800546 | c.-263T>G | upstream_gene_variant | 0.31 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.38 | linezolid | |
rplC | 800576 | c.-233C>T | upstream_gene_variant | 0.4 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.42 | linezolid | |
rplC | 800591 | c.-218C>T | upstream_gene_variant | 0.43 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.42 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.45 | linezolid | |
rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.49 | linezolid | |
rplC | 800648 | c.-161A>T | upstream_gene_variant | 0.46 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.44 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.45 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.46 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.39 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.38 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.35 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.29 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.26 | linezolid | |
fbiC | 1303489 | c.559C>T | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303509 | c.579G>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303521 | c.591C>T | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303530 | c.600G>A | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303584 | c.654C>G | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303623 | c.693C>T | synonymous_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303632 | c.702T>G | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303695 | c.765T>C | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303704 | c.774T>C | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303728 | c.798G>A | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303731 | c.801A>C | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303732 | p.Ser268Ala | missense_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303737 | c.807G>A | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303746 | c.816T>C | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303749 | c.819G>C | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303752 | c.822A>G | synonymous_variant | 0.26 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303755 | c.825T>C | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303764 | c.834C>T | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303785 | c.855G>C | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303797 | c.867A>G | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303881 | c.951G>C | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303905 | c.975G>C | synonymous_variant | 0.42 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303911 | c.981G>C | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303944 | c.1014G>C | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303947 | c.1017T>G | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303956 | c.1026A>G | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303961 | p.Arg344Leu | missense_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303971 | c.1041T>C | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303973 | p.Gly348Ala | missense_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303980 | c.1050G>A | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304004 | c.1074A>G | synonymous_variant | 0.42 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304022 | c.1092T>C | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304031 | c.1101C>G | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304040 | c.1110C>A | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304046 | c.1116C>G | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304049 | c.1119T>A | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304050 | c.1120T>C | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304058 | c.1128G>A | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304059 | c.1129C>T | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304064 | c.1134G>C | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304067 | c.1137G>C | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304091 | p.Asp387Glu | missense_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304092 | p.Met388Leu | missense_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304097 | c.1167G>C | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304115 | c.1185A>G | synonymous_variant | 0.42 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304127 | c.1197A>G | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304132 | p.Ala401Gly | missense_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304154 | c.1224G>C | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304162 | p.Arg411Gln | missense_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304166 | c.1236A>G | synonymous_variant | 0.19 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304169 | c.1239T>C | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304173 | p.Val415Thr | missense_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304178 | c.1248G>A | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304181 | c.1251G>A | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304199 | c.1269C>T | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304613 | c.1683T>A | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304658 | c.1728C>G | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304661 | c.1731C>T | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304670 | c.1740G>C | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304671 | p.Val581Thr | missense_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304675 | p.Gly582Asp | missense_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304691 | c.1761G>C | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304694 | c.1764A>C | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304703 | c.1773C>G | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304711 | p.Ala594Glu | missense_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304715 | c.1785G>C | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304724 | c.1794A>G | synonymous_variant | 0.4 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304727 | c.1797A>G | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304787 | c.1857T>G | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304799 | c.1869G>T | synonymous_variant | 0.49 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.45 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.54 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304832 | c.1902C>T | synonymous_variant | 0.54 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304853 | c.1923C>T | synonymous_variant | 0.55 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.52 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304869 | c.1939C>T | synonymous_variant | 0.51 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304875 | p.Ile649Val | missense_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304883 | p.Glu651Asp | missense_variant | 0.49 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304889 | c.1959G>C | synonymous_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304891 | p.Ile654Thr | missense_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304907 | c.1977C>G | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304910 | c.1980G>C | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304925 | c.1995G>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304940 | c.2010A>G | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304955 | c.2025G>A | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
sigE | 1364434 | p.Arg8Trp | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 0.2 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472044 | n.199G>T | non_coding_transcript_exon_variant | 0.24 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.3 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.31 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.38 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.37 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472300 | n.455C>T | non_coding_transcript_exon_variant | 0.46 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.38 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.35 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.37 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.37 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.48 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.48 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.47 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.39 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.27 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.39 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 0.48 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.56 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.53 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.45 | capreomycin | |
linezolid | ||||||
rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 0.45 | capreomycin | |
linezolid | ||||||
rrl | 1474044 | n.387C>T | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474054 | n.397T>C | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474093 | n.436G>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1474099 | n.442G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474904 | n.1247G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1474956 | n.1299C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1474960 | n.1303C>G | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1474962 | n.1305T>C | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474963 | n.1306G>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474964 | n.1307T>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1474965 | n.1308G>C | non_coding_transcript_exon_variant | 0.31 | capreomycin | |
linezolid | ||||||
rrl | 1474970 | n.1313G>A | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1475006 | n.1349A>C | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1475013 | n.1356G>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475436 | n.1779C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475573 | n.1916G>A | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
inhA | 1673574 | c.-628C>G | upstream_gene_variant | 0.18 | ethionamide | |
isoniazid | ||||||
inhA | 1673580 | c.-622T>C | upstream_gene_variant | 0.19 | ethionamide | |
isoniazid | Uncertain significance | |||||
inhA | 1673607 | c.-595T>C | upstream_gene_variant | 0.21 | ethionamide | |
isoniazid | ||||||
inhA | 1673616 | c.-586A>G | upstream_gene_variant | 0.24 | ethionamide | |
isoniazid | ||||||
inhA | 1673619 | c.-583T>C | upstream_gene_variant | 0.24 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673633 | p.Ser65Asn | missense_variant | 0.27 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673641 | p.Val68Ile | missense_variant | 0.26 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673657 | p.Thr73Lys | missense_variant | 0.21 | ethionamide | |
isoniazid | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 0.28 | ethionamide | |
isoniazid | ||||||
inhA | 1674708 | c.507G>A | synonymous_variant | 0.28 | ethionamide | |
isoniazid | ||||||
inhA | 1674718 | c.517_519delAGGinsCT | frameshift_variant&missense_variant | 0.23 | ethionamide | |
isoniazid | ||||||
inhA | 1674732 | c.531C>T | synonymous_variant | 0.28 | ethionamide | |
isoniazid | ||||||
inhA | 1674738 | c.537C>G | synonymous_variant | 0.28 | ethionamide | |
isoniazid | ||||||
inhA | 1674746 | p.Tyr182Phe | missense_variant | 0.27 | ethionamide | |
isoniazid | ||||||
inhA | 1674753 | c.552G>C | synonymous_variant | 0.25 | ethionamide | |
isoniazid | ||||||
inhA | 1674756 | c.555T>C | synonymous_variant | 0.25 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674774 | c.573A>C | synonymous_variant | 0.23 | ethionamide | |
isoniazid | ||||||
inhA | 1674780 | c.579T>G | synonymous_variant | 0.24 | ethionamide | |
isoniazid | ||||||
inhA | 1674816 | c.615T>C | synonymous_variant | 0.34 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674846 | p.Ile215Met | missense_variant | 0.31 | ethionamide | |
isoniazid | ||||||
inhA | 1674849 | c.648G>A | synonymous_variant | 0.29 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674861 | c.660G>A | synonymous_variant | 0.25 | ethionamide | |
isoniazid | ||||||
inhA | 1674870 | c.669T>C | synonymous_variant | 0.27 | ethionamide | |
isoniazid | ||||||
inhA | 1674879 | c.678T>G | synonymous_variant | 0.26 | ethionamide | |
isoniazid | ||||||
inhA | 1674903 | c.702T>C | synonymous_variant | 0.26 | ethionamide | |
isoniazid | ||||||
inhA | 1674904 | c.703_705delGCGinsCC | frameshift_variant&missense_variant | 0.25 | ethionamide | |
isoniazid | ||||||
inhA | 1674909 | c.708G>A | synonymous_variant | 0.26 | ethionamide | |
isoniazid | ||||||
rpsA | 1833610 | c.69C>T | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1833748 | c.207C>G | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1833772 | c.231C>T | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1833808 | c.267G>C | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1833835 | c.294C>T | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1833868 | c.327C>T | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833971 | c.430C>T | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834105 | c.564C>G | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834108 | c.567C>A | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834123 | c.582C>G | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1834150 | c.609G>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834153 | c.612T>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834154 | c.613_615delAACinsCG | frameshift_variant&missense_variant | 0.3 | pyrazinamide | Uncertain significance |
rpsA | 1834157 | c.616T>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834162 | c.621A>G | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834165 | c.624A>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834169 | p.Thr210Ala | missense_variant | 0.29 | pyrazinamide | Uncertain significance |
rpsA | 1834177 | c.636A>C | synonymous_variant | 0.31 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834189 | c.648G>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834264 | c.723G>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834303 | c.762T>G | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834339 | c.798C>T | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.49 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.46 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.49 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1834474 | c.933C>G | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1834480 | c.939C>G | synonymous_variant | 0.54 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1834540 | c.999G>T | synonymous_variant | 0.48 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1834606 | c.1065C>T | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834619 | c.1078T>C | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.33 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.49 | pyrazinamide | |
rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Ser | missense_variant | 0.5 | pyrazinamide | |
rpsA | 1834738 | c.1197A>G | synonymous_variant | 0.52 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1834759 | c.1218A>C | synonymous_variant | 0.52 | pyrazinamide | |
rpsA | 1834765 | p.Glu408Asp | missense_variant | 0.47 | pyrazinamide | |
rpsA | 1834775 | p.Ala412Thr | missense_variant | 0.45 | pyrazinamide | |
rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.36 | pyrazinamide | |
tsnR | 1853360 | c.-246G>A | upstream_gene_variant | 0.21 | linezolid | |
tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.21 | linezolid | |
tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.24 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.25 | linezolid | |
tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.3 | linezolid | |
tsnR | 1853426 | c.-180G>A | upstream_gene_variant | 0.28 | linezolid | |
tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.29 | linezolid | |
tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 0.29 | linezolid | |
tsnR | 1853444 | c.-162C>G | upstream_gene_variant | 0.22 | linezolid | |
tsnR | 1853447 | c.-159C>G | upstream_gene_variant | 0.23 | linezolid | |
tsnR | 1853459 | c.-147G>C | upstream_gene_variant | 0.22 | linezolid | |
tsnR | 1853477 | c.-129T>C | upstream_gene_variant | 0.18 | linezolid | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 0.98 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
tlyA | 1918002 | c.63A>G | synonymous_variant | 0.26 | capreomycin | |
tlyA | 1918026 | c.87C>G | synonymous_variant | 0.23 | capreomycin | |
ndh | 2101894 | c.1149T>C | synonymous_variant | 0.24 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101912 | c.1131G>C | synonymous_variant | 0.25 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101918 | c.1123_1125delAGGinsCA | frameshift_variant&missense_variant | 0.25 | ethionamide | Uncertain significance |
delamanid | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
ndh | 2101924 | c.1119T>G | synonymous_variant | 0.25 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
katG | 2154279 | c.1833C>T | synonymous_variant | 0.91 | isoniazid | Not assoc w R - Interim |
katG | 2155068 | c.1044T>C | synonymous_variant | 0.21 | isoniazid | |
katG | 2155071 | c.1041T>C | synonymous_variant | 0.21 | isoniazid | |
katG | 2155113 | c.999C>G | synonymous_variant | 0.21 | isoniazid | |
katG | 2155119 | c.991_993delAGTinsTCC | synonymous_variant | 0.21 | isoniazid | |
katG | 2155131 | c.981A>G | synonymous_variant | 0.22 | isoniazid | Not assoc w R - Interim |
katG | 2155140 | c.972C>G | synonymous_variant | 0.22 | isoniazid | |
katG | 2155144 | p.Asn323Pro | missense_variant | 0.23 | isoniazid | |
katG | 2155152 | c.960A>C | synonymous_variant | 0.22 | isoniazid | |
katG | 2155716 | c.396T>G | synonymous_variant | 0.25 | isoniazid | |
katG | 2155722 | c.390G>C | synonymous_variant | 0.29 | isoniazid | |
katG | 2155740 | p.Gly124Gln | missense_variant | 0.27 | isoniazid | |
katG | 2155743 | c.369G>C | synonymous_variant | 0.27 | isoniazid | |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
kasA | 2517917 | c.-198G>C | upstream_gene_variant | 0.32 | isoniazid | |
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.2 | isoniazid | |
kasA | 2517974 | c.-141T>C | upstream_gene_variant | 0.24 | isoniazid | |
kasA | 2518504 | c.390T>C | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518506 | p.Ala131Glu | missense_variant | 0.3 | isoniazid | |
kasA | 2518519 | c.405G>C | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518528 | c.414C>G | synonymous_variant | 0.37 | isoniazid | |
kasA | 2518540 | c.426T>G | synonymous_variant | 0.39 | isoniazid | |
kasA | 2518561 | c.447T>C | synonymous_variant | 0.41 | isoniazid | |
kasA | 2518574 | c.460_462delATCinsGG | frameshift_variant&missense_variant | 0.39 | isoniazid | |
kasA | 2518588 | c.474T>C | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518591 | c.477G>C | synonymous_variant | 0.38 | isoniazid | |
kasA | 2518609 | p.Met165Ile | missense_variant | 0.38 | isoniazid | |
kasA | 2518618 | c.504G>T | synonymous_variant | 0.39 | isoniazid | |
kasA | 2518642 | c.528A>G | synonymous_variant | 0.41 | isoniazid | |
kasA | 2518666 | c.552G>A | synonymous_variant | 0.37 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.37 | isoniazid | |
kasA | 2518678 | c.564C>T | synonymous_variant | 0.32 | isoniazid | |
kasA | 2518687 | c.573C>T | synonymous_variant | 0.33 | isoniazid | |
kasA | 2518688 | p.Val192Phe | missense_variant | 0.33 | isoniazid | |
kasA | 2518702 | c.588C>T | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518705 | c.591T>C | synonymous_variant | 0.34 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 0.37 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.37 | isoniazid | |
kasA | 2518723 | c.609G>A | synonymous_variant | 0.33 | isoniazid | |
kasA | 2518765 | c.651G>C | synonymous_variant | 0.38 | isoniazid | |
kasA | 2518768 | c.654C>T | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518777 | c.663C>T | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518780 | c.666G>A | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518789 | c.675G>C | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518792 | c.678C>A | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518796 | c.682C>A | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518816 | c.702C>T | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518831 | c.717C>T | synonymous_variant | 0.28 | isoniazid | |
kasA | 2518834 | c.720C>T | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518853 | p.Leu247Ile | missense_variant | 0.23 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518879 | c.765A>G | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518885 | c.771T>C | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518990 | c.876T>G | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518993 | c.879C>A | synonymous_variant | 0.26 | isoniazid | |
kasA | 2519008 | c.894C>G | synonymous_variant | 0.31 | isoniazid | |
kasA | 2519017 | c.903G>C | synonymous_variant | 0.27 | isoniazid | |
kasA | 2519020 | c.906G>C | synonymous_variant | 0.24 | isoniazid | |
kasA | 2519021 | p.Ala303Lys | missense_variant | 0.24 | isoniazid | |
kasA | 2519027 | c.913_915delATCinsGT | frameshift_variant&missense_variant | 0.22 | isoniazid | |
kasA | 2519035 | c.921C>T | synonymous_variant | 0.26 | isoniazid | |
kasA | 2519050 | c.936C>G | synonymous_variant | 0.29 | isoniazid | |
kasA | 2519062 | c.948T>G | synonymous_variant | 0.26 | isoniazid | |
kasA | 2519068 | c.954C>T | synonymous_variant | 0.28 | isoniazid | |
kasA | 2519072 | p.Ala320Thr | missense_variant | 0.29 | isoniazid | |
kasA | 2519095 | c.981C>G | synonymous_variant | 0.34 | isoniazid | |
kasA | 2519107 | c.993T>C | synonymous_variant | 0.33 | isoniazid | |
kasA | 2519108 | c.994_996delGATinsCG | frameshift_variant&missense_variant | 0.33 | isoniazid | |
kasA | 2519113 | c.999G>A | synonymous_variant | 0.35 | isoniazid | |
kasA | 2519116 | c.1002C>G | synonymous_variant | 0.35 | isoniazid | |
kasA | 2519122 | c.1008G>C | synonymous_variant | 0.34 | isoniazid | |
kasA | 2519137 | c.1023T>G | synonymous_variant | 0.28 | isoniazid | |
kasA | 2519158 | c.1044C>T | synonymous_variant | 0.33 | isoniazid | |
kasA | 2519167 | c.1053T>G | synonymous_variant | 0.35 | isoniazid | |
kasA | 2519173 | c.1059C>G | synonymous_variant | 0.35 | isoniazid | |
kasA | 2519196 | p.Thr361Ser | missense_variant | 0.31 | isoniazid | |
ahpC | 2726633 | c.441C>T | synonymous_variant | 0.34 | isoniazid | |
ahpC | 2726638 | p.Ala149Val | missense_variant | 0.34 | isoniazid | |
ahpC | 2726645 | c.453C>G | synonymous_variant | 0.32 | isoniazid | |
ahpC | 2726657 | c.465A>C | synonymous_variant | 0.29 | isoniazid | Not assoc w R - Interim |
ahpC | 2726669 | p.Asp159Glu | missense_variant | 0.24 | isoniazid | |
ahpC | 2726672 | c.480G>A | synonymous_variant | 0.24 | isoniazid | Not assoc w R - Interim |
ahpC | 2726675 | c.483A>G | synonymous_variant | 0.26 | isoniazid | |
ahpC | 2726681 | c.489A>C | synonymous_variant | 0.26 | isoniazid | Not assoc w R - Interim |
ahpC | 2726693 | c.501C>A | synonymous_variant | 0.29 | isoniazid | |
ahpC | 2726696 | c.504C>G | synonymous_variant | 0.29 | isoniazid | |
ahpC | 2726717 | c.525A>G | synonymous_variant | 0.27 | isoniazid | |
folC | 2747343 | p.Val86Ile | missense_variant | 0.29 | para-aminosalicylic_acid | |
folC | 2747355 | p.Val82Ile | missense_variant | 0.29 | para-aminosalicylic_acid | |
folC | 2747359 | c.240C>G | synonymous_variant | 0.3 | para-aminosalicylic_acid | |
folC | 2747362 | c.237G>C | synonymous_variant | 0.32 | para-aminosalicylic_acid | |
folC | 2747394 | p.Ile69Val | missense_variant | 0.25 | para-aminosalicylic_acid | |
folC | 2747407 | c.192T>C | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
folC | 2747434 | c.165C>T | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
folC | 2747442 | c.157T>C | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
folC | 2747443 | c.156G>C | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
Rv2477c | 2782928 | p.Thr372Glu | missense_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782936 | c.1107G>T | synonymous_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 0.26 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782972 | c.1071G>C | synonymous_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 0.31 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783035 | c.1008G>C | synonymous_variant | 0.3 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 0.29 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783044 | c.999G>A | synonymous_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783048 | p.Asp332Gly | missense_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783051 | p.Tyr331Phe | missense_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783083 | c.960G>C | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783098 | c.945C>G | synonymous_variant | 0.2 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783101 | c.942G>T | synonymous_variant | 0.2 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783140 | c.903C>G | synonymous_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783146 | c.897G>A | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783149 | c.894G>C | synonymous_variant | 0.27 | ethambutol | |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783158 | c.885A>C | synonymous_variant | 0.31 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783182 | c.861C>G | synonymous_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.3 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783221 | c.822G>C | synonymous_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783224 | c.819C>G | synonymous_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783230 | c.813T>G | synonymous_variant | 0.38 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783254 | c.789A>G | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783263 | c.780G>C | synonymous_variant | 0.44 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783275 | c.768C>G | synonymous_variant | 0.49 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783278 | c.765A>G | synonymous_variant | 0.51 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783287 | c.756C>G | synonymous_variant | 0.54 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783293 | c.750G>A | synonymous_variant | 0.55 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783299 | c.744A>G | synonymous_variant | 0.47 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783302 | c.741A>G | synonymous_variant | 0.47 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783311 | c.732T>C | synonymous_variant | 0.43 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783314 | c.729C>G | synonymous_variant | 0.43 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783317 | c.726G>C | synonymous_variant | 0.43 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783332 | c.711T>C | synonymous_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783335 | c.708C>G | synonymous_variant | 0.43 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783353 | c.690T>C | synonymous_variant | 0.37 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783359 | c.684G>A | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783473 | c.570A>C | synonymous_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783485 | c.558G>C | synonymous_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783497 | c.544_546delTTGinsCC | frameshift_variant&missense_variant | 0.24 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783502 | c.541T>C | synonymous_variant | 0.24 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783512 | c.531A>G | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783539 | c.504G>C | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783542 | c.501G>C | synonymous_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783545 | c.498C>G | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783548 | c.495T>C | synonymous_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783554 | c.489C>T | synonymous_variant | 0.35 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783563 | c.480A>G | synonymous_variant | 0.37 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783572 | c.471A>G | synonymous_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.37 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783620 | c.423C>G | synonymous_variant | 0.36 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783626 | c.415_417delGCGinsTA | frameshift_variant&missense_variant | 0.33 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783659 | c.384A>G | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783766 | p.Met93Leu | missense_variant | 0.37 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783770 | c.273G>A | synonymous_variant | 0.37 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783776 | c.267G>C | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783779 | c.264T>C | synonymous_variant | 0.37 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783815 | c.228A>G | synonymous_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783821 | p.Gln74Leu | missense_variant | 0.37 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783833 | c.210G>C | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783839 | c.204C>G | synonymous_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783846 | p.Thr66Asn | missense_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783860 | c.183T>C | synonymous_variant | 0.45 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783863 | c.180C>T | synonymous_variant | 0.43 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783883 | c.160T>C | synonymous_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783884 | c.159T>C | synonymous_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783887 | c.156C>T | synonymous_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783914 | c.129T>C | synonymous_variant | 0.58 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783920 | c.123G>C | synonymous_variant | 0.62 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783929 | c.114C>G | synonymous_variant | 0.52 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783932 | c.111C>T | synonymous_variant | 0.52 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783953 | c.90G>A | synonymous_variant | 0.42 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783962 | c.81T>C | synonymous_variant | 0.38 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | ||||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783968 | c.75G>A | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783971 | c.72G>C | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783980 | c.63C>G | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783992 | c.51T>C | synonymous_variant | 0.36 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2784016 | c.27G>A | synonymous_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2752c | 3064914 | c.1278T>G | synonymous_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064928 | c.1264T>C | synonymous_variant | 0.44 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064932 | c.1260T>C | synonymous_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064935 | c.1257A>G | synonymous_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064941 | c.1249_1251delCAAinsGG | frameshift_variant&missense_variant | 0.4 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv2752c | 3064947 | c.1245A>G | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064956 | c.1234_1236delAGTinsCC | frameshift_variant&missense_variant | 0.41 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv2752c | 3064962 | c.1230C>G | synonymous_variant | 0.43 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064973 | p.Ala407Ser | missense_variant | 0.37 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064974 | c.1218T>C | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064995 | c.1197C>G | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064998 | c.1194A>G | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065007 | c.1185G>C | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065013 | c.1179G>C | synonymous_variant | 0.36 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065016 | c.1174_1176delAACinsCT | frameshift_variant&missense_variant | 0.36 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv2752c | 3065022 | c.1170G>T | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065028 | c.1162_1164delGTGinsAT | frameshift_variant&missense_variant | 0.38 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv2752c | 3065040 | c.1152C>G | synonymous_variant | 0.35 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
Rv2752c | 3065421 | c.771G>C | synonymous_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065451 | c.741G>A | synonymous_variant | 0.3 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065457 | c.735A>C | synonymous_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065460 | c.732G>T | synonymous_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065463 | c.729T>C | synonymous_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065481 | c.711T>C | synonymous_variant | 0.31 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
Rv2752c | 3065487 | c.705T>G | synonymous_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065490 | c.702A>C | synonymous_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065493 | c.699G>C | synonymous_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065496 | c.696G>C | synonymous_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065499 | c.693A>C | synonymous_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065508 | c.684T>C | synonymous_variant | 0.31 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
Rv2752c | 3065511 | c.681G>C | synonymous_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065517 | c.675C>G | synonymous_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065520 | c.672G>C | synonymous_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065532 | c.660A>G | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065535 | c.657C>T | synonymous_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065547 | c.645A>G | synonymous_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065979 | c.213T>C | synonymous_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065985 | c.207C>T | synonymous_variant | 0.3 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
Rv2752c | 3065988 | c.204A>G | synonymous_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065993 | p.Val67Ile | missense_variant | 0.29 | ethambutol | Uncertain significance |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv2752c | 3066002 | p.Met64Leu | missense_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066003 | c.189C>T | synonymous_variant | 0.32 | ethambutol | |
moxifloxacin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066009 | c.183G>C | synonymous_variant | 0.34 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066018 | c.174T>C | synonymous_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066024 | c.168T>G | synonymous_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066050 | p.Leu48Met | missense_variant | 0.45 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066054 | c.138T>G | synonymous_variant | 0.48 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066066 | c.126T>C | synonymous_variant | 0.43 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066069 | c.121_123delTTGinsCC | frameshift_variant&missense_variant | 0.43 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv2752c | 3066075 | c.117A>G | synonymous_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066087 | c.105A>G | synonymous_variant | 0.35 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
Rv2752c | 3066090 | c.100_102delTTCinsCG | frameshift_variant&missense_variant | 0.33 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv2752c | 3066118 | p.Asn25Ser | missense_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
thyX | 3067349 | c.597G>C | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067355 | c.591A>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067367 | c.579G>C | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
thyX | 3067391 | c.555G>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067394 | c.552G>C | synonymous_variant | 0.3 | para-aminosalicylic_acid | |
thyX | 3067661 | c.285C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067682 | c.264G>A | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067715 | c.231C>T | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067718 | c.228C>G | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067721 | c.225T>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067727 | c.219A>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067736 | c.210C>T | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyX | 3067765 | p.Leu61Ile | missense_variant | 0.16 | para-aminosalicylic_acid | |
thyX | 3067781 | c.165C>G | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067799 | c.147G>A | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067802 | c.144C>G | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067811 | c.135G>A | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067814 | c.132T>C | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067850 | c.96A>C | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067869 | p.Thr26Ser | missense_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067874 | c.72C>G | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
thyX | 3067883 | c.63C>G | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
thyX | 3067886 | c.60A>C | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067889 | c.57C>G | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067898 | p.Asp16Glu | missense_variant | 0.27 | para-aminosalicylic_acid | |
thyA | 3073868 | p.Thr202Ala | missense_variant | 0.86 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
Rv3236c | 3612009 | p.Ala370Thr | missense_variant | 0.89 | pyrazinamide | Not assoc w R |
Rv3236c | 3612349 | c.768A>C | synonymous_variant | 0.26 | pyrazinamide | |
Rv3236c | 3612388 | c.729T>C | synonymous_variant | 0.24 | pyrazinamide | |
Rv3236c | 3612715 | c.402G>C | synonymous_variant | 0.19 | pyrazinamide | |
Rv3236c | 3612721 | c.396G>C | synonymous_variant | 0.19 | pyrazinamide | |
Rv3236c | 3612724 | c.393T>C | synonymous_variant | 0.2 | pyrazinamide | |
Rv3236c | 3612730 | c.387C>G | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
Rv3236c | 3612736 | c.381T>C | synonymous_variant | 0.19 | pyrazinamide | |
Rv3236c | 3612748 | c.369G>C | synonymous_variant | 0.2 | pyrazinamide | |
lpqB | 3624656 | c.255C>T | synonymous_variant | 0.2 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624701 | c.210T>C | synonymous_variant | 0.3 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624707 | c.204G>C | synonymous_variant | 0.28 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624722 | c.189C>G | synonymous_variant | 0.31 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624728 | c.183C>T | synonymous_variant | 0.32 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624749 | c.162G>A | synonymous_variant | 0.35 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624755 | c.154_156delTTAinsCG | frameshift_variant&missense_variant | 0.33 | bedaquiline | |
rifampicin | Uncertain significance | |||||
lpqB | 3624770 | c.141T>C | synonymous_variant | 0.31 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624776 | c.135T>C | synonymous_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | bedaquiline | Uncertain significance |
rifampicin | Not assoc w R | |||||
mtrB | 3625093 | p.Glu507Asp | missense_variant | 0.22 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625099 | c.-189C>G | upstream_gene_variant | 0.21 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625105 | c.1509C>A | synonymous_variant | 0.3 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625117 | c.-207T>G | upstream_gene_variant | 0.32 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625123 | c.-213T>C | upstream_gene_variant | 0.35 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625134 | c.-224T>C | upstream_gene_variant | 0.31 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625135 | c.1479A>G | synonymous_variant | 0.31 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625138 | c.-228C>G | upstream_gene_variant | 0.32 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625141 | c.-231T>C | upstream_gene_variant | 0.31 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625149 | p.Val489Ile | missense_variant | 0.31 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625161 | c.-251T>C | upstream_gene_variant | 0.34 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625162 | c.1452T>C | synonymous_variant | 0.33 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625165 | c.-255G>C | upstream_gene_variant | 0.35 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625186 | c.-276T>C | upstream_gene_variant | 0.36 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625189 | c.1425A>G | synonymous_variant | 0.37 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625195 | c.-285A>G | upstream_gene_variant | 0.37 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625201 | c.-291T>C | upstream_gene_variant | 0.37 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625206 | p.Ser470Ala | missense_variant | 0.36 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625222 | c.1392T>C | synonymous_variant | 0.33 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625240 | c.-330T>C | upstream_gene_variant | 0.33 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625243 | c.-333T>C | upstream_gene_variant | 0.3 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625569 | c.1045T>C | synonymous_variant | 0.43 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625572 | p.Thr348Ser | missense_variant | 0.43 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 0.45 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625592 | p.Ser341Asn | missense_variant | 0.41 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 0.44 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.49 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 0.47 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625616 | p.Arg333Ala | missense_variant | 0.47 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 0.51 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625636 | c.978C>G | synonymous_variant | 0.5 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625656 | c.958T>C | synonymous_variant | 0.51 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.48 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 0.48 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.48 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.48 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 0.49 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625705 | c.909C>G | synonymous_variant | 0.41 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625711 | c.903C>T | synonymous_variant | 0.36 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 0.33 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625720 | c.894G>C | synonymous_variant | 0.36 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625729 | c.885A>G | synonymous_variant | 0.34 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625732 | c.882C>T | synonymous_variant | 0.33 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 0.33 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.33 | bedaquiline | |
rifampicin | Uncertain significance | |||||
lpqB | 3625762 | c.-852A>C | upstream_gene_variant | 0.36 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 0.36 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625774 | c.840G>A | synonymous_variant | 0.34 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625777 | c.-867C>G | upstream_gene_variant | 0.33 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625797 | p.Val273Met | missense_variant | 0.36 | bedaquiline | Uncertain significance |
rifampicin | Uncertain significance | |||||
lpqB | 3625803 | c.-893C>T | upstream_gene_variant | 0.36 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.33 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625807 | c.807C>G | synonymous_variant | 0.33 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625840 | c.-930A>G | upstream_gene_variant | 0.33 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 0.36 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625852 | c.762A>G | synonymous_variant | 0.37 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 0.34 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625876 | c.738G>C | synonymous_variant | 0.28 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625882 | c.-972G>C | upstream_gene_variant | 0.29 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625909 | c.-999T>C | upstream_gene_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626101 | p.Gln171His | missense_variant | 0.32 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626107 | c.507G>C | synonymous_variant | 0.33 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626110 | c.504C>G | synonymous_variant | 0.33 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626116 | c.498G>A | synonymous_variant | 0.35 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626124 | p.Ala164Ser | missense_variant | 0.41 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626125 | c.489C>G | synonymous_variant | 0.39 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626146 | c.468C>T | synonymous_variant | 0.36 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626155 | c.459G>C | synonymous_variant | 0.39 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626158 | c.456C>T | synonymous_variant | 0.39 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626170 | c.444T>C | synonymous_variant | 0.37 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626185 | c.429T>G | synonymous_variant | 0.3 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626188 | c.424_426delTCTinsAC | frameshift_variant&missense_variant | 0.32 | bedaquiline | Uncertain significance |
rifampicin | Uncertain significance | |||||
mtrB | 3626191 | c.423C>G | synonymous_variant | 0.33 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626194 | c.420T>G | synonymous_variant | 0.32 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626206 | c.408T>C | synonymous_variant | 0.3 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626209 | c.405T>C | synonymous_variant | 0.3 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 0.25 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3626774 | c.574_576delAGGinsCC | frameshift_variant&missense_variant | 0.29 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 0.28 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626786 | c.564A>G | synonymous_variant | 0.28 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3626792 | c.558G>T | synonymous_variant | 0.28 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 0.28 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 0.29 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.36 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 0.36 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 0.37 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 0.4 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 0.43 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 0.48 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626869 | c.481C>T | synonymous_variant | 0.42 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626885 | c.-272A>C | upstream_gene_variant | 0.5 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 0.5 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626900 | c.-287G>A | upstream_gene_variant | 0.5 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 0.5 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626912 | c.-299T>G | upstream_gene_variant | 0.48 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 0.48 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626939 | c.411A>G | synonymous_variant | 0.46 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 0.49 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 0.49 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 0.42 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 0.42 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627065 | c.-452G>C | upstream_gene_variant | 0.52 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 0.52 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627074 | c.-461G>C | upstream_gene_variant | 0.5 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627080 | c.270T>C | synonymous_variant | 0.45 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 0.45 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627098 | c.252A>C | synonymous_variant | 0.56 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.53 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627119 | c.231T>G | synonymous_variant | 0.5 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.52 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627125 | c.-512C>G | upstream_gene_variant | 0.53 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 0.44 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627175 | c.175C>T | synonymous_variant | 0.44 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3627188 | c.162A>G | synonymous_variant | 0.42 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627196 | c.-583C>T | upstream_gene_variant | 0.44 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 0.44 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627221 | c.129C>T | synonymous_variant | 0.38 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3627227 | c.123T>C | synonymous_variant | 0.44 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 0.43 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.46 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627242 | c.108C>T | synonymous_variant | 0.44 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.41 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 0.36 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 0.36 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 0.33 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627275 | c.-662G>T | upstream_gene_variant | 0.32 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 0.32 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627299 | c.49_51delTTGinsCA | frameshift_variant&missense_variant | 0.33 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627314 | c.-701C>T | upstream_gene_variant | 0.32 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 0.32 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627343 | p.Thr3Ser | missense_variant | 0.25 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627360 | c.-747G>C | upstream_gene_variant | 0.22 | bedaquiline | |
rifampicin | ||||||
fbiB | 3640920 | c.-615A>T | upstream_gene_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3642560 | c.1026T>C | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3642566 | c.1032A>C | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3642572 | c.1038A>G | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3642581 | c.1047A>C | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3642587 | p.Met351Ile | missense_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3642596 | c.1062C>G | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3642602 | c.1068A>C | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3642605 | c.1071A>C | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3642609 | c.1075_1076delAGinsTC | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiB | 3642620 | c.1086T>C | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
alr | 3840944 | c.477T>C | synonymous_variant | 0.25 | cycloserine | |
alr | 3840947 | c.474G>C | synonymous_variant | 0.28 | cycloserine | |
alr | 3840959 | c.462G>C | synonymous_variant | 0.31 | cycloserine | |
alr | 3840962 | c.459G>C | synonymous_variant | 0.31 | cycloserine | |
alr | 3840968 | c.453G>C | synonymous_variant | 0.3 | cycloserine | |
alr | 3840977 | c.444C>G | synonymous_variant | 0.27 | cycloserine | |
alr | 3840980 | c.441G>C | synonymous_variant | 0.27 | cycloserine | |
alr | 3840994 | p.His143Asp | missense_variant | 0.33 | cycloserine | |
alr | 3840997 | c.424T>C | synonymous_variant | 0.33 | cycloserine | |
alr | 3841001 | c.420A>G | synonymous_variant | 0.34 | cycloserine | |
alr | 3841010 | c.411A>G | synonymous_variant | 0.33 | cycloserine | |
alr | 3841017 | p.Leu135Glu | missense_variant | 0.32 | cycloserine | |
alr | 3841022 | c.399C>G | synonymous_variant | 0.31 | cycloserine | |
alr | 3841028 | c.393G>C | synonymous_variant | 0.31 | cycloserine | |
alr | 3841033 | p.Val130Ile | missense_variant | 0.31 | cycloserine | |
alr | 3841037 | c.382_384delGTGinsAC | frameshift_variant&missense_variant | 0.3 | cycloserine | |
alr | 3841059 | p.Gly121Ala | missense_variant | 0.3 | cycloserine | |
rpoA | 3877488 | c.1020C>T | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3877494 | p.Glu338Asp | missense_variant | 0.24 | rifampicin | Uncertain significance |
rpoA | 3877503 | c.1005G>C | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3877507 | p.Gly334Ala | missense_variant | 0.25 | rifampicin | |
rpoA | 3877515 | c.993G>C | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3877553 | p.Glu319Gln | missense_variant | 0.33 | rifampicin | |
rpoA | 3877560 | c.948C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoA | 3877571 | p.Pro313Ala | missense_variant | 0.39 | rifampicin | |
rpoA | 3877587 | c.921A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoA | 3877593 | c.915C>T | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.52 | rifampicin | |
rpoA | 3877656 | c.852T>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoA | 3877668 | c.840A>G | synonymous_variant | 0.57 | rifampicin | |
rpoA | 3877679 | p.Ala277Ser | missense_variant | 0.57 | rifampicin | |
rpoA | 3877686 | c.822A>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>T | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoA | 3877743 | c.765T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoA | 3877791 | c.717C>G | synonymous_variant | 0.51 | rifampicin | |
rpoA | 3877794 | c.714G>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoA | 3877818 | c.690A>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoA | 3877848 | c.660C>T | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoA | 3877857 | c.651G>A | synonymous_variant | 0.58 | rifampicin | |
rpoA | 3877872 | c.636C>T | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoA | 3877875 | c.633T>G | synonymous_variant | 0.54 | rifampicin | |
rpoA | 3877881 | c.627G>A | synonymous_variant | 0.5 | rifampicin | |
rpoA | 3877896 | c.612G>C | synonymous_variant | 0.46 | rifampicin | |
rpoA | 3877900 | p.Ser203Asn | missense_variant | 0.46 | rifampicin | |
rpoA | 3877905 | c.603A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoA | 3877908 | p.Asn200Ser | missense_variant | 0.44 | rifampicin | |
rpoA | 3877920 | c.588G>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoA | 3877926 | c.582G>C | synonymous_variant | 0.44 | rifampicin | |
rpoA | 3877962 | c.546G>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoA | 3877989 | c.519A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878001 | c.507A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878022 | c.486T>C | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3878028 | c.480G>C | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878031 | c.477T>C | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3878034 | c.474A>G | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3878040 | c.468T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoA | 3878043 | c.465G>T | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3878046 | c.462T>A | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878055 | c.453A>G | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878061 | c.447G>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878067 | c.441C>G | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878070 | c.438T>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878076 | c.432C>T | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878094 | c.414C>G | synonymous_variant | 0.32 | rifampicin | |
rpoA | 3878103 | c.405A>G | synonymous_variant | 0.32 | rifampicin | |
rpoA | 3878106 | c.402G>C | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878118 | c.390T>C | synonymous_variant | 0.39 | rifampicin | |
rpoA | 3878130 | c.378C>G | synonymous_variant | 0.37 | rifampicin | |
rpoA | 3878141 | p.Met123Leu | missense_variant | 0.38 | rifampicin | Uncertain significance |
rpoA | 3878143 | p.Gly122Asp | missense_variant | 0.39 | rifampicin | Uncertain significance |
rpoA | 3878157 | c.351C>G | synonymous_variant | 0.38 | rifampicin | |
rpoA | 3878169 | c.339G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoA | 3878172 | c.336G>C | synonymous_variant | 0.42 | rifampicin | |
rpoA | 3878175 | c.333G>T | synonymous_variant | 0.43 | rifampicin | |
rpoA | 3878184 | c.324C>T | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoA | 3878187 | c.321C>G | synonymous_variant | 0.46 | rifampicin | |
rpoA | 3878193 | c.315T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoA | 3878199 | c.309T>C | synonymous_variant | 0.47 | rifampicin | |
rpoA | 3878205 | c.303T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoA | 3878217 | c.291A>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoA | 3878226 | c.282C>G | synonymous_variant | 0.43 | rifampicin | |
rpoA | 3878247 | c.261G>C | synonymous_variant | 0.38 | rifampicin | |
rpoA | 3878256 | c.252G>C | synonymous_variant | 0.33 | rifampicin | |
rpoA | 3878331 | c.177A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoA | 3878364 | c.144A>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878367 | c.141C>G | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3878376 | c.132G>C | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3878385 | c.123C>G | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3878388 | c.120C>G | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3878391 | c.117T>C | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3878396 | c.112C>T | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3878415 | c.93C>T | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3878436 | c.72A>G | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3878442 | c.66G>C | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3878454 | c.54A>C | synonymous_variant | 0.26 | rifampicin | |
rpoA | 3878460 | c.48C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoA | 3878716 | c.-209C>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3878725 | c.-218A>G | upstream_gene_variant | 0.26 | rifampicin | |
rpoA | 3878736 | c.-229A>G | upstream_gene_variant | 0.28 | rifampicin | |
rpoA | 3878737 | c.-230G>C | upstream_gene_variant | 0.27 | rifampicin | |
rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 0.29 | rifampicin | |
rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 0.3 | rifampicin | Uncertain significance |
rpoA | 3878761 | c.-254G>C | upstream_gene_variant | 0.31 | rifampicin | |
rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 0.33 | rifampicin | |
rpoA | 3878785 | c.-278T>G | upstream_gene_variant | 0.33 | rifampicin | |
rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.33 | rifampicin | Uncertain significance |
rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 0.34 | rifampicin | |
rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.35 | rifampicin | |
rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 0.31 | rifampicin | |
rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.26 | rifampicin | |
rpoA | 3878836 | c.-331_-329delAAGinsTCC | upstream_gene_variant | 0.25 | rifampicin | |
rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.2 | rifampicin | |
rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 0.3 | rifampicin | Uncertain significance |
rpoA | 3879005 | c.-499_-498delAAinsCG | upstream_gene_variant | 0.32 | rifampicin | |
rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 0.4 | rifampicin | |
rpoA | 3879022 | c.-515G>C | upstream_gene_variant | 0.38 | rifampicin | |
rpoA | 3879033 | c.-526C>T | upstream_gene_variant | 0.38 | rifampicin | |
rpoA | 3879034 | c.-527G>A | upstream_gene_variant | 0.38 | rifampicin | |
rpoA | 3879061 | c.-554C>T | upstream_gene_variant | 0.43 | rifampicin | |
rpoA | 3879073 | c.-566A>G | upstream_gene_variant | 0.47 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.44 | rifampicin | |
rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 0.43 | rifampicin | |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.39 | rifampicin | |
rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.39 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.4 | rifampicin | |
rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.35 | rifampicin | |
rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.31 | rifampicin | |
rpoA | 3879178 | c.-671T>C | upstream_gene_variant | 0.23 | rifampicin | |
ddn | 3986621 | c.-223G>C | upstream_gene_variant | 0.35 | delamanid | |
pretomanid | ||||||
ddn | 3986645 | c.-199G>A | upstream_gene_variant | 0.27 | delamanid | |
pretomanid | ||||||
clpC1 | 4038287 | c.2418C>T | synonymous_variant | 0.6 | pyrazinamide | Not assoc w R |
clpC1 | 4038347 | c.2358G>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4038359 | c.2346A>G | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4038388 | c.2317T>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4038392 | c.2313C>T | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4038398 | c.2307G>T | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4038403 | c.2302T>C | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038407 | c.2298G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4038419 | c.2286T>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4038433 | c.2272C>T | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4038434 | c.2271G>A | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4038444 | p.Ala754Lys | missense_variant | 0.19 | pyrazinamide | |
clpC1 | 4038446 | c.2259T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4038456 | p.Val750Glu | missense_variant | 0.2 | pyrazinamide | |
clpC1 | 4038458 | c.2247G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038486 | p.Gly740Thr | missense_variant | 0.22 | pyrazinamide | |
clpC1 | 4038498 | p.Ser736Thr | missense_variant | 0.24 | pyrazinamide | |
clpC1 | 4038596 | c.2109A>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038815 | c.1890G>A | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4038845 | c.1860G>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.42 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.43 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4038923 | c.1780_1782delCTAinsTG | frameshift_variant&synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.46 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.41 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.45 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039043 | c.1662G>T | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039064 | c.1641C>T | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039085 | c.1620A>G | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.36 | pyrazinamide | |
clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039183 | c.1522T>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039186 | c.1519C>T | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4039193 | c.1512C>G | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039208 | c.1497C>G | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.34 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.39 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4039319 | c.1386T>C | synonymous_variant | 0.42 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039328 | c.1377A>C | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4039331 | c.1374C>G | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4039337 | p.Thr456Gln | missense_variant | 0.38 | pyrazinamide | |
clpC1 | 4039349 | c.1356C>T | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4039352 | c.1353C>G | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4039364 | c.1341C>G | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4039391 | c.1314T>G | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4039406 | c.1299G>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039409 | c.1296T>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039412 | c.1293T>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039415 | p.Glu430Asp | missense_variant | 0.31 | pyrazinamide | Uncertain significance |
clpC1 | 4039430 | c.1275T>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039442 | c.1263A>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039454 | c.1251A>T | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039576 | p.Ala377Pro | missense_variant | 0.35 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.36 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039589 | c.1116G>T | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>T | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4039661 | c.1044T>G | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4039664 | c.1041G>C | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039756 | c.949C>T | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039757 | c.948A>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039760 | c.945T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039775 | c.930G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039781 | c.924G>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039790 | c.915C>G | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039817 | c.888A>T | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039820 | c.885T>C | synonymous_variant | 0.24 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039904 | c.801A>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039937 | c.768G>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039946 | c.759A>T | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039964 | c.741C>T | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039979 | c.726C>T | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4040087 | c.618G>T | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4040090 | c.615T>C | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.35 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040162 | c.543G>C | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040165 | c.540G>C | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4040171 | c.534C>G | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4040201 | c.504C>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4040207 | c.498T>G | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4040213 | c.490_492delTCTinsAGC | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4040225 | c.480A>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4040228 | c.477G>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4040231 | c.474C>T | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4040237 | c.468C>T | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4040246 | c.459C>G | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4040249 | c.456A>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4040267 | c.438A>G | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040277 | c.427_428delTCinsAG | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4040279 | c.426C>G | synonymous_variant | 0.24 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4040522 | c.183T>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
panD | 4044635 | c.-354G>C | upstream_gene_variant | 0.21 | pyrazinamide | |
panD | 4044643 | c.-362G>T | upstream_gene_variant | 0.21 | pyrazinamide | |
panD | 4044650 | c.-369G>C | upstream_gene_variant | 0.21 | pyrazinamide | |
panD | 4044653 | c.-372C>G | upstream_gene_variant | 0.21 | pyrazinamide | |
panD | 4044662 | c.-381C>G | upstream_gene_variant | 0.2 | pyrazinamide | |
panD | 4044668 | c.-387G>C | upstream_gene_variant | 0.21 | pyrazinamide | |
panD | 4044677 | c.-396T>C | upstream_gene_variant | 0.2 | pyrazinamide | |
panD | 4044682 | c.-401C>A | upstream_gene_variant | 0.22 | pyrazinamide | |
panD | 4044692 | c.-411G>C | upstream_gene_variant | 0.2 | pyrazinamide | |
panD | 4044700 | c.-419C>A | upstream_gene_variant | 0.22 | pyrazinamide | |
panD | 4044704 | c.-423G>C | upstream_gene_variant | 0.22 | pyrazinamide | |
panD | 4044709 | c.-428A>G | upstream_gene_variant | 0.21 | pyrazinamide | |
panD | 4044712 | c.-431C>A | upstream_gene_variant | 0.22 | pyrazinamide | |
panD | 4044737 | c.-456T>G | upstream_gene_variant | 0.2 | pyrazinamide | |
panD | 4044748 | c.-467G>A | upstream_gene_variant | 0.19 | pyrazinamide | |
glpK | 4138670 | c.1086G>T | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138796 | c.960A>G | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138802 | c.954G>A | synonymous_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138808 | c.948G>T | synonymous_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138817 | c.939T>C | synonymous_variant | 0.3 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138822 | p.Asn312Asp | missense_variant | 0.3 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138829 | c.927A>G | synonymous_variant | 0.3 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
embC | 4240671 | p.Thr270Ile | missense_variant | 0.19 | ethambutol | Not assoc w R |
embC | 4240675 | c.813C>T | synonymous_variant | 0.19 | ethambutol | |
embC | 4240702 | c.840G>A | synonymous_variant | 0.18 | ethambutol | |
embC | 4241050 | c.1188T>G | synonymous_variant | 0.23 | ethambutol | |
embC | 4241053 | c.1191G>C | synonymous_variant | 0.23 | ethambutol | |
embC | 4241081 | c.1219C>T | synonymous_variant | 0.29 | ethambutol | |
embC | 4241089 | c.1227C>G | synonymous_variant | 0.33 | ethambutol | |
embC | 4241095 | c.1233C>T | synonymous_variant | 0.36 | ethambutol | |
embC | 4241107 | c.1245G>C | synonymous_variant | 0.36 | ethambutol | |
embC | 4241131 | c.1269G>A | synonymous_variant | 0.38 | ethambutol | |
embC | 4241140 | c.1278A>G | synonymous_variant | 0.34 | ethambutol | Not assoc w R - Interim |
embC | 4241146 | c.1284C>G | synonymous_variant | 0.32 | ethambutol | |
embC | 4241158 | c.1296T>G | synonymous_variant | 0.31 | ethambutol | Not assoc w R - Interim |
embC | 4241161 | c.1299C>G | synonymous_variant | 0.31 | ethambutol | Not assoc w R - Interim |
embC | 4241162 | c.1300T>C | synonymous_variant | 0.3 | ethambutol | |
embC | 4241374 | c.1512T>C | synonymous_variant | 0.17 | ethambutol | |
embC | 4241380 | c.1518A>C | synonymous_variant | 0.19 | ethambutol | |
embC | 4241383 | c.1521G>C | synonymous_variant | 0.22 | ethambutol | Not assoc w R - Interim |
embC | 4241394 | p.Lys511Ser | missense_variant | 0.23 | ethambutol | |
embC | 4241443 | c.1581C>T | synonymous_variant | 0.31 | ethambutol | |
embC | 4242643 | c.2781C>T | synonymous_variant | 0.86 | ethambutol | Not assoc w R |
embA | 4242739 | c.-494C>G | upstream_gene_variant | 0.23 | ethambutol | |
embA | 4242742 | c.-491C>G | upstream_gene_variant | 0.24 | ethambutol | |
embA | 4242745 | c.-488A>G | upstream_gene_variant | 0.24 | ethambutol | |
embC | 4242746 | c.2884_2886delCCAinsTG | frameshift_variant&stop_gained | 0.24 | ethambutol | |
embA | 4242754 | c.-479G>C | upstream_gene_variant | 0.22 | ethambutol | |
embC | 4242762 | p.Arg967Gln | missense_variant | 0.21 | ethambutol | |
embC | 4242764 | p.Val968Leu | missense_variant | 0.21 | ethambutol | |
embC | 4242779 | p.Asn973Asp | missense_variant | 0.24 | ethambutol | |
embC | 4242791 | c.2929_2931delGCAinsTG | frameshift_variant&stop_gained | 0.21 | ethambutol | |
embA | 4242796 | c.-437G>C | upstream_gene_variant | 0.22 | ethambutol | |
embA | 4242799 | c.-434T>C | upstream_gene_variant | 0.22 | ethambutol | |
embA | 4242809 | c.-424C>T | upstream_gene_variant | 0.21 | ethambutol | |
embA | 4242820 | c.-413G>C | upstream_gene_variant | 0.21 | ethambutol | |
embA | 4242823 | c.-410G>C | upstream_gene_variant | 0.19 | ethambutol | |
embA | 4242832 | c.-401A>G | upstream_gene_variant | 0.17 | ethambutol | |
embA | 4245083 | c.1851A>C | synonymous_variant | 0.19 | ethambutol | |
embA | 4245101 | c.1869G>A | synonymous_variant | 0.18 | ethambutol | Not assoc w R - Interim |
embA | 4245137 | c.1905T>C | synonymous_variant | 0.21 | ethambutol | |
embB | 4247879 | c.1366_1368delGTGinsAC | frameshift_variant&missense_variant | 0.18 | ethambutol | |
embB | 4247893 | c.1380C>A | synonymous_variant | 0.21 | ethambutol | |
embB | 4248070 | c.1557T>C | synonymous_variant | 0.19 | ethambutol | |
embB | 4248088 | c.1575C>T | synonymous_variant | 0.18 | ethambutol | |
embB | 4248097 | c.1584C>G | synonymous_variant | 0.22 | ethambutol | |
embB | 4248100 | c.1587C>T | synonymous_variant | 0.22 | ethambutol | Not assoc w R - Interim |
embB | 4248106 | c.1593C>T | synonymous_variant | 0.21 | ethambutol | Not assoc w R - Interim |
embB | 4248115 | c.1602C>T | synonymous_variant | 0.19 | ethambutol | Not assoc w R |
embB | 4248118 | c.1605T>C | synonymous_variant | 0.2 | ethambutol | |
embB | 4248142 | c.1629T>C | synonymous_variant | 0.19 | ethambutol | |
embB | 4248143 | c.1630T>C | synonymous_variant | 0.19 | ethambutol | |
embB | 4248157 | c.1644A>G | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
embB | 4248160 | c.1647C>T | synonymous_variant | 0.23 | ethambutol | Not assoc w R - Interim |
embB | 4248169 | c.1656C>G | synonymous_variant | 0.27 | ethambutol | |
embB | 4248172 | c.1659G>C | synonymous_variant | 0.26 | ethambutol | |
embB | 4248200 | p.Ile563Val | missense_variant | 0.27 | ethambutol | |
embB | 4248205 | c.1692C>G | synonymous_variant | 0.27 | ethambutol | |
embB | 4248206 | c.1693_1695delAGCinsGA | frameshift_variant&missense_variant | 0.27 | ethambutol | |
embB | 4248220 | c.1707A>T | synonymous_variant | 0.26 | ethambutol | |
embB | 4248241 | c.1728C>T | synonymous_variant | 0.26 | ethambutol | |
embB | 4248307 | c.1794G>C | synonymous_variant | 0.29 | ethambutol | |
embB | 4248416 | p.Leu635Val | missense_variant | 0.28 | ethambutol | |
embB | 4248424 | c.1911G>C | synonymous_variant | 0.26 | ethambutol | |
embB | 4248475 | c.1962G>A | synonymous_variant | 0.21 | ethambutol | |
embB | 4249417 | c.2904A>T | synonymous_variant | 0.17 | ethambutol | |
aftB | 4268105 | c.732T>C | synonymous_variant | 0.26 | ethambutol | |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | capreomycin | Not assoc w R |
amikacin | Not assoc w R | |||||
kanamycin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
gid | 4408156 | p.Leu16Arg | missense_variant | 0.9 | streptomycin | Not assoc w R |