TB-Profiler result

Run: SRR16156832
Summary

Run ID: SRR16156832

Sample name:

Date: 2024-04-15T17:24:08.732568

Number of reads: 484229

Percentage reads mapped: 12.11

Median coverage: 6.0

Strain: lineage2.2;lineage4

Spoligotype:

Drug-resistance: RR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage2 East-Asian RD105 0.19
lineage2.2 East-Asian (Beijing) RD105;RD207 0.28
lineage4 Euro-American None 0.7
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1321_1323delTCGinsGC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
p.Leu464Met Mutation from literature
isoniazid
ethambutol
pyrazinamide
streptomycin rrs n.799C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
capreomycin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
kanamycin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpoB 761127 c.1321_1323delTCGinsGC frameshift_variant&missense_variant 0.97 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
rpoB 761196 p.Leu464Met missense_variant 0.94 rifampicin Mutation from literature
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance Mutation from literature
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 1.0 amikacin Uncertain significance Mutation from literature
capreomycin Uncertain significance Mutation from literature
kanamycin Uncertain significance Mutation from literature
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.97 capreomycin Assoc w R
amikacin Assoc w R
kanamycin Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
rpoB 760916 c.1110C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760920 c.1114_1116delCTGinsAC frameshift_variant&missense_variant 0.91 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.9 rifampicin
rpoB 760926 p.Thr374Ala missense_variant 0.94 rifampicin
rpoB 760931 c.1125C>G synonymous_variant 0.93 rifampicin
rpoB 760944 c.1138_1140delCAAinsGG frameshift_variant&missense_variant 0.94 rifampicin
rpoB 760958 c.1152G>C synonymous_variant 0.94 rifampicin
rpoB 760959 p.Val385Thr missense_variant 0.94 rifampicin
rpoB 760965 p.Met387Leu missense_variant 0.94 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.92 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.97 rifampicin
rpoB 760997 c.1191G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761088 c.1282_1284delAGCinsTCG synonymous_variant 0.94 rifampicin
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.9 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.96 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761138 c.1332C>G synonymous_variant 0.97 rifampicin
rpoB 761147 c.1341C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761156 c.1350G>C synonymous_variant 0.94 rifampicin
rpoB 761162 c.1356G>C synonymous_variant 0.94 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.94 rifampicin
rpoB 761174 c.1368T>C synonymous_variant 0.94 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761183 c.1377T>C synonymous_variant 0.94 rifampicin
rpoB 761186 p.Glu460Asp missense_variant 0.94 rifampicin Uncertain significance
rpoB 761195 c.1389G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.94 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.94 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761243 c.1437G>C synonymous_variant 0.85 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761963 c.2157G>C synonymous_variant 0.8 rifampicin
rpoB 761974 p.His723Leu missense_variant 0.97 rifampicin
rpoB 762003 c.2197_2199delAACinsCG frameshift_variant&missense_variant 0.97 rifampicin
rpoB 762009 p.Leu735Met missense_variant 0.97 rifampicin
rpoB 762015 p.Glu737Ser missense_variant 0.97 rifampicin
rpoB 762026 c.2220G>C synonymous_variant 0.97 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762057 p.Ile751Val missense_variant 0.98 rifampicin Uncertain significance
rpoB 762062 c.2256T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762098 c.2292C>G synonymous_variant 1.0 rifampicin
rpoB 762101 c.2295C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762110 c.2304G>C synonymous_variant 1.0 rifampicin
rpoB 762114 c.2308_2310delATCinsGG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.88 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.88 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762410 c.2604T>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762426 p.Ser874Thr missense_variant 0.89 rifampicin Uncertain significance
rpoC 762434 c.-936T>C upstream_gene_variant 0.89 rifampicin
rpoB 762441 p.Leu879Met missense_variant 0.85 rifampicin
rpoB 762452 c.2646G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762474 p.Gly890Ser missense_variant 0.85 rifampicin
rpoB 762489 c.2683_2685delGTTinsCC frameshift_variant&missense_variant 0.89 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.89 rifampicin
rpoC 762512 c.-858C>G upstream_gene_variant 0.89 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762832 p.Ser1009Thr missense_variant 0.86 rifampicin Uncertain significance
rpoB 762849 p.Tyr1015Asp missense_variant 0.91 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762858 c.3052_3054delACGinsTC frameshift_variant&missense_variant 0.91 rifampicin
rpoC 762863 c.-507T>G upstream_gene_variant 0.95 rifampicin
rpoB 762866 c.3060C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762878 p.Ile1024Met missense_variant 0.91 rifampicin
rpoB 762879 c.3073_3075delATGinsCC frameshift_variant&missense_variant 0.91 rifampicin
rpoB 762920 c.3114C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 762926 c.-444C>G upstream_gene_variant 0.96 rifampicin
rpoB 762929 c.3123G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 762947 c.-423C>G upstream_gene_variant 0.96 rifampicin
rpoC 762971 c.-399G>C upstream_gene_variant 0.94 rifampicin
rpoC 762980 c.-390T>A upstream_gene_variant 0.85 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763483 c.114G>C synonymous_variant 0.97 rifampicin
rpoC 763486 c.117T>G synonymous_variant 0.97 rifampicin
rpoC 763504 c.135C>A synonymous_variant 0.99 rifampicin
rpoC 763507 c.138G>C synonymous_variant 0.99 rifampicin
rpoC 763528 c.159G>C synonymous_variant 0.99 rifampicin
rpoC 763531 c.162G>C synonymous_variant 0.99 rifampicin Not assoc w R
rpoC 763534 c.165T>C synonymous_variant 0.99 rifampicin
rpoC 763537 c.168C>T synonymous_variant 0.99 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763550 p.Tyr61Ala missense_variant 0.98 rifampicin
rpoC 763570 c.201G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763622 c.253_255delGCCinsTG frameshift_variant&missense_variant 0.94 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.93 rifampicin
rpoC 763639 p.Glu90Asp missense_variant 0.93 rifampicin
rpoC 763642 c.273G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.92 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 0.92 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.93 rifampicin
rpoC 763751 p.Ile128Val missense_variant 0.92 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763772 p.Val135Met missense_variant 0.87 rifampicin
rpoC 763786 c.417C>G synonymous_variant 0.89 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.84 rifampicin
rpoC 764359 c.990C>G synonymous_variant 0.87 rifampicin
rpoC 764371 c.1002G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.96 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.99 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764441 p.Ile358Leu missense_variant 0.96 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.96 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.96 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.95 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.97 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764498 p.Ser377Ala missense_variant 0.96 rifampicin
rpoC 764507 c.1138_1140delGCGinsTC frameshift_variant&missense_variant 0.97 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764542 c.1173C>G synonymous_variant 0.98 rifampicin
rpoC 764548 c.1179G>C synonymous_variant 0.98 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>C synonymous_variant 0.99 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.99 rifampicin
rpoC 764582 p.Leu405Met missense_variant 0.99 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764635 c.1266C>G synonymous_variant 0.98 rifampicin
rpoC 764650 c.1281G>C synonymous_variant 0.98 rifampicin
rpoC 764665 c.1296C>G synonymous_variant 0.98 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764671 c.1302G>C synonymous_variant 0.96 rifampicin
rpoC 764695 c.1326T>C synonymous_variant 0.96 rifampicin
rpoC 764706 p.Leu446Gln missense_variant 0.95 rifampicin Uncertain significance
rpoC 764746 c.1377G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764749 c.1380G>C synonymous_variant 0.97 rifampicin
rpoC 764758 c.1389C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764780 c.1411_1412delAGinsTC synonymous_variant 0.97 rifampicin
rpoC 764804 p.Gln479Phe missense_variant 0.94 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 0.96 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.94 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764818 c.1449G>C synonymous_variant 0.96 rifampicin
rpoC 764824 c.1455T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764833 c.1464A>G synonymous_variant 0.98 rifampicin
rpoC 764843 p.Ala492Thr missense_variant 0.97 rifampicin
rpoC 764857 c.1488G>C synonymous_variant 0.95 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>C synonymous_variant 0.96 rifampicin
rpoC 764887 c.1518G>T synonymous_variant 0.83 rifampicin
rpoC 764888 c.1519T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.83 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.82 rifampicin
rpoC 765888 p.Phe840Tyr missense_variant 0.83 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765902 p.Thr845Ser missense_variant 0.9 rifampicin
rpoC 765910 c.2541G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765920 p.Ile851Ser missense_variant 0.84 rifampicin Uncertain significance
rpoC 765923 p.Asn852Ala missense_variant 0.86 rifampicin
rpoC 765937 c.2568T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>C synonymous_variant 0.84 rifampicin
rpoC 765947 c.2578_2580delTTGinsCC frameshift_variant&missense_variant 0.83 rifampicin
rpoC 765962 c.2593T>C synonymous_variant 0.82 rifampicin
rpoC 765965 p.Arg866Lys missense_variant 0.84 rifampicin
rpoC 765973 c.2604C>G synonymous_variant 0.82 rifampicin
rpoC 765974 p.Asp869Asn missense_variant 0.83 rifampicin
rpoC 765979 c.2610C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 766000 c.2631G>C synonymous_variant 0.81 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.8 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.76 rifampicin
rpoC 766034 p.His889Asp missense_variant 0.72 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.83 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.85 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.82 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472293 n.448C>A non_coding_transcript_exon_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472313 n.468delGinsAA non_coding_transcript_exon_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.85 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.85 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.85 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472389 n.544G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472674 n.829T>A non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472686 n.841G>T non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473022 n.1177G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473026 n.1181T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473089 n.1244A>T non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473292 n.1447_1449delGGAinsTGGG non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473317 n.1472G>A non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1474124 n.467G>C non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474125 n.468C>G non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474133 n.476T>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474141 n.484G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474142 n.485C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474186 n.529A>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474275 n.618T>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474280 n.623C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474317 n.660G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474381 n.724T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474414 n.757_778delCCCACACGCGCATACGCGCGTGinsT non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474444 n.787G>C non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474662 n.1005C>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474688 n.1031G>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474710 n.1053T>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474711 n.1054_1055insAA non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474714 n.1058delT non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474717 n.1060A>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474784 n.1127C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475688 n.2031G>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475713 n.2056C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475747 n.2090A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475757 n.2101_2104delACCC non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475765 n.2108A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475766 n.2109G>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475781 n.2124T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid Uncertain significance
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476253 n.2596A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476308 n.2651G>C non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.96 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.96 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.96 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833653 p.Ile38Leu missense_variant 0.9 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.9 pyrazinamide
rpsA 1833668 p.Ile43Val missense_variant 0.9 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.92 pyrazinamide
rpsA 1833685 c.144G>C synonymous_variant 0.95 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833733 c.192C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 1.0 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833763 c.222C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833769 c.228C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833770 p.Asn77Asp missense_variant 1.0 pyrazinamide
rpsA 1833781 c.240T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833782 p.Ser81Ala missense_variant 1.0 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833794 p.Glu85Thr missense_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833835 c.294C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833850 c.309C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.89 pyrazinamide
rpsA 1833877 c.336C>G synonymous_variant 0.83 pyrazinamide
rpsA 1833884 p.Thr115Asp missense_variant 0.84 pyrazinamide
rpsA 1833893 p.Ala118Lys missense_variant 0.83 pyrazinamide
rpsA 1833896 p.Leu119Ile missense_variant 0.83 pyrazinamide
rpsA 1833905 p.Lys122Glu missense_variant 0.83 pyrazinamide
rpsA 1833912 p.Glu124Gly missense_variant 0.83 pyrazinamide
rpsA 1833915 p.Ala125Val missense_variant 0.79 pyrazinamide Uncertain significance
rpsA 1833920 p.Lys127Glu missense_variant 0.84 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.91 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.92 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.94 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 0.94 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.93 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.94 pyrazinamide
rpsA 1833985 c.444G>C synonymous_variant 0.94 pyrazinamide
rpsA 1833988 c.447C>G synonymous_variant 0.94 pyrazinamide
rpsA 1833994 c.453G>C synonymous_variant 0.94 pyrazinamide
rpsA 1833997 c.456G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834025 p.Gln162Ala missense_variant 0.96 pyrazinamide
rpsA 1834040 p.Lys167Gln missense_variant 0.97 pyrazinamide
rpsA 1834043 p.Glu168Lys missense_variant 0.97 pyrazinamide
rpsA 1834046 p.Ile169Leu missense_variant 0.97 pyrazinamide
rpsA 1834054 c.513C>G synonymous_variant 0.96 pyrazinamide
rpsA 1834093 c.552G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.9 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834219 c.678C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834243 c.702G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834298 p.Gln253Glu missense_variant 0.97 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.97 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834307 c.766_768delGACinsCG frameshift_variant&missense_variant 0.97 pyrazinamide Uncertain significance
rpsA 1834327 c.786G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834333 p.Asp264Glu missense_variant 0.98 pyrazinamide
rpsA 1834336 c.795C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
rpsA 1834354 c.813G>T synonymous_variant 0.97 pyrazinamide
rpsA 1834357 c.816T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834360 c.819G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
rpsA 1834369 c.828C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1834384 c.843A>G synonymous_variant 0.99 pyrazinamide
rpsA 1834395 p.Arg285Gln missense_variant 0.99 pyrazinamide
rpsA 1834398 p.His286Leu missense_variant 0.98 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834418 p.Ile293Leu missense_variant 0.96 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834427 p.Ile296Val missense_variant 0.98 pyrazinamide Uncertain significance
rpsA 1834451 c.910_912delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834456 c.915T>G synonymous_variant 0.98 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.98 pyrazinamide
rpsA 1834480 c.939C>G synonymous_variant 0.96 pyrazinamide
rpsA 1834486 p.Glu315Asp missense_variant 0.98 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834501 c.960G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.96 pyrazinamide
rpoA 3877587 c.921A>C synonymous_variant 0.75 rifampicin
rpoA 3877601 p.Gln303Glu missense_variant 0.75 rifampicin
rpoA 3877602 p.His302Gln missense_variant 0.75 rifampicin
rpoA 3877605 c.903G>C synonymous_variant 0.75 rifampicin
rpoA 3877611 p.Ile299Glu missense_variant 0.75 rifampicin
rpoA 3877617 c.891G>C synonymous_variant 0.75 rifampicin
rpoA 3877636 p.Gln291Ala missense_variant 0.9 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877656 c.850_852delCTTinsAG frameshift_variant&missense_variant 0.9 rifampicin
rpoA 3877667 p.Ser281Ala missense_variant 0.9 rifampicin
rpoA 3877668 c.840A>G synonymous_variant 0.9 rifampicin
rpoA 3877671 c.835_837delACCinsTG frameshift_variant&missense_variant 0.9 rifampicin
rpoA 3877674 c.834C>G synonymous_variant 0.9 rifampicin
rpoA 3877677 p.Ala277Gly missense_variant 0.9 rifampicin
rpoA 3877683 c.825G>C synonymous_variant 0.9 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877701 c.805_807delGTGinsAC frameshift_variant&missense_variant 0.75 rifampicin
rpoA 3877704 c.804G>C synonymous_variant 0.75 rifampicin
clpC1 4038756 p.Gly650Ser missense_variant 0.89 pyrazinamide
clpC1 4038764 c.1941C>G synonymous_variant 0.86 pyrazinamide
clpC1 4038767 c.1938G>A synonymous_variant 0.86 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.86 pyrazinamide
clpC1 4038782 c.1921_1923delGTGinsAC frameshift_variant&missense_variant 0.86 pyrazinamide
clpC1 4038795 c.1909_1910delAGinsTC synonymous_variant 0.9 pyrazinamide
clpC1 4038801 p.Tyr635Phe missense_variant 0.86 pyrazinamide
clpC1 4038805 p.Ile634Leu missense_variant 0.86 pyrazinamide
clpC1 4038806 p.Glu633Asp missense_variant 0.86 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.87 pyrazinamide
clpC1 4038824 c.1879_1881delATCinsGG frameshift_variant&missense_variant 0.87 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.9 pyrazinamide
clpC1 4038854 p.Lys617Arg missense_variant 0.9 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4038863 c.1842G>C synonymous_variant 0.86 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4039714 p.Tyr331His missense_variant 0.88 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.91 pyrazinamide
clpC1 4039730 c.975C>G synonymous_variant 0.91 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.93 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039773 p.Lys311Met missense_variant 0.95 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.95 pyrazinamide
clpC1 4039814 c.891C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.97 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 0.92 pyrazinamide
clpC1 4039823 c.882T>G synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4039829 c.874_876delTTGinsCC frameshift_variant&missense_variant 0.89 pyrazinamide
clpC1 4039838 c.865_867delCTGinsAC frameshift_variant&missense_variant 0.93 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039865 c.840T>G synonymous_variant 0.94 pyrazinamide
clpC1 4039871 c.834C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039875 p.Asn277Arg missense_variant 0.93 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.87 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.87 pyrazinamide
clpC1 4039916 c.789T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039929 c.775_776delAGinsTC synonymous_variant 0.88 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.88 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039940 c.765G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039943 c.762G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.88 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039960 p.Thr249Ser missense_variant 0.94 pyrazinamide
clpC1 4039977 p.Lys243Arg missense_variant 0.97 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039994 p.Glu237Asp missense_variant 0.98 pyrazinamide
clpC1 4040001 p.His235Arg missense_variant 0.98 pyrazinamide
clpC1 4040003 p.Val234Asp missense_variant 0.98 pyrazinamide
clpC1 4040009 c.696C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 0.96 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.96 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.98 pyrazinamide
clpC1 4040063 c.642G>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040069 c.636G>C synonymous_variant 0.93 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 0.9 pyrazinamide
clpC1 4040090 c.615T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4040108 c.597G>C synonymous_variant 0.83 pyrazinamide