Run ID: c3a50fb9-4309-411d-b92d-0c956d76d723
Sample name:
Date: 25-05-2023 17:06:12
Number of reads: 8926902
Percentage reads mapped: 82.05
Median coverage: 272
Strain: lineage5.3;lineage5.1.4
Spoligotype:
Drug-resistance: Other
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage5 | West-Africa 1 | RD711 | 0.89 |
| La1.2.BCG | M.bovis | None | 0.06 |
| lineage5.3 | West-Africa 1 | RD711 | 0.72 |
| lineage5.1 | West-Africa 1 | RD711 | 0.22 |
| lineage5.1.4 | West-Africa 1 | RD711 | 0.26 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | embB | p.His312Arg | Uncertain significance | |
| p.Leu359Ile | Uncertain significance | |||
| pyrazinamide | ||||
| moxifloxacin | ||||
| levofloxacin | ||||
| bedaquiline | ||||
| delamanid | ||||
| pretomanid | ||||
| linezolid | ||||
| streptomycin | rrs | n.462C>T | Uncertain significance | |
| amikacin | ||||
| kanamycin | ||||
| capreomycin | ||||
| clofazimine | ||||
| ethionamide | ||||
| para-aminosalicylic_acid | ||||
| cycloserine |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.21 | streptomycin | Uncertain significance | |
| embB | 4247448 | p.His312Arg | missense_variant | 0.12 | ethambutol | Uncertain significance | |
| embB | 4247588 | p.Leu359Ile | missense_variant | 0.12 | ethambutol | Uncertain significance |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| gyrB | 5081 | c.-159G>C | upstream_gene_variant | 0.26 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6196 | c.957C>T | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6238 | c.999G>A | synonymous_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6242 | p.Arg335Lys | missense_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6250 | c.1011A>G | synonymous_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6256 | c.1017G>A | synonymous_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6268 | c.1029C>G | synonymous_variant | 0.18 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6280 | c.1041T>C | synonymous_variant | 0.2 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6286 | c.1047T>C | synonymous_variant | 0.19 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6289 | c.1050C>T | synonymous_variant | 0.18 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6292 | c.1053G>C | synonymous_variant | 0.18 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6307 | c.-995T>G | upstream_gene_variant | 0.19 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6319 | c.-983G>C | upstream_gene_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6362 | c.-940T>C | upstream_gene_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6446 | p.Ala403Ser | missense_variant | 0.98 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6649 | c.-653T>C | upstream_gene_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6655 | c.-647T>C | upstream_gene_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6728 | c.-574_-572delCTAinsTTG | upstream_gene_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6742 | c.-560A>G | upstream_gene_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6811 | c.-491C>T | upstream_gene_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6841 | c.-461T>C | upstream_gene_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6844 | c.-458T>C | upstream_gene_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6853 | c.-449A>G | upstream_gene_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6856 | c.-446T>C | upstream_gene_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6859 | c.-443T>C | upstream_gene_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6862 | c.-440C>G | upstream_gene_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6868 | c.-434G>C | upstream_gene_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6877 | c.-425G>T | upstream_gene_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6878 | c.-424T>C | upstream_gene_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6881 | c.-421_-419delTTGinsCTC | upstream_gene_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6889 | c.-413G>T | upstream_gene_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6901 | c.-401G>C | upstream_gene_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6904 | c.-398C>G | upstream_gene_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6910 | c.-392G>A | upstream_gene_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6919 | c.-383T>C | upstream_gene_variant | 0.18 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6925 | c.-377T>C | upstream_gene_variant | 0.2 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6931 | c.-371A>G | upstream_gene_variant | 0.19 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6949 | c.-353A>G | upstream_gene_variant | 0.18 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6952 | c.-350C>G | upstream_gene_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6967 | c.-335T>C | upstream_gene_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6973 | c.-329G>C | upstream_gene_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6982 | c.-320A>C | upstream_gene_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7006 | c.-296T>C | upstream_gene_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7007 | c.-295C>T | upstream_gene_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7010 | c.-292C>T | upstream_gene_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7015 | c.-287G>A | upstream_gene_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7018 | c.-284G>A | upstream_gene_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 7023 | p.Leu595Gln | missense_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7033 | c.-269G>C | upstream_gene_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 7051 | p.Glu604Asp | missense_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7066 | c.-236G>C | upstream_gene_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7075 | c.-227T>C | upstream_gene_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7078 | c.-224A>C | upstream_gene_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7084 | c.-218A>G | upstream_gene_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7090 | c.-212C>T | upstream_gene_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7093 | c.-209T>G | upstream_gene_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7099 | c.-203G>A | upstream_gene_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7102 | c.-200G>A | upstream_gene_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7108 | c.-194G>A | upstream_gene_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7114 | c.-188C>A | upstream_gene_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 7124 | p.Ser629Thr | missense_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7129 | c.-173T>C | upstream_gene_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7141 | c.-161T>C | upstream_gene_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7147 | c.-155G>C | upstream_gene_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7165 | c.-137C>G | upstream_gene_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7178 | c.-124T>C | upstream_gene_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7186 | c.-116C>G | upstream_gene_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7347 | p.Glu16Gln | missense_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7361 | c.60C>T | synonymous_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7391 | c.90C>T | synonymous_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 0.18 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7427 | c.126G>C | synonymous_variant | 0.2 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7442 | c.141G>C | synonymous_variant | 0.18 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7490 | c.189C>G | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7523 | c.222C>G | synonymous_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7532 | c.231T>G | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7547 | c.246C>T | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7571 | c.270G>C | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7595 | c.294C>G | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7601 | c.300C>G | synonymous_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7607 | c.306C>T | synonymous_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7622 | c.321C>T | synonymous_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7625 | c.324G>C | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7637 | c.336C>G | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7652 | c.351C>T | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7658 | c.357A>C | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7664 | c.363T>C | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7670 | c.369A>G | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7679 | c.378G>C | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7685 | c.384G>A | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7688 | c.387C>T | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7694 | c.393A>G | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7697 | c.396C>G | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7710 | c.409_411delTTGinsCTC | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7715 | c.414G>C | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7721 | c.420G>A | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7725 | c.424C>T | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7728 | c.427_429delAGGinsCGT | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7763 | c.462T>C | synonymous_variant | 0.19 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7775 | c.474C>A | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7781 | c.480G>C | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7784 | c.483A>G | synonymous_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8121 | c.820T>C | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8129 | c.828T>C | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8135 | c.834C>G | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8156 | c.855T>C | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8168 | c.867A>G | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8177 | c.876A>C | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8198 | c.897T>C | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8207 | c.906T>C | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8219 | c.918T>C | synonymous_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8225 | c.924T>C | synonymous_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8234 | c.933T>C | synonymous_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8237 | c.936A>G | synonymous_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8247 | p.Ile316Val | missense_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8264 | c.963T>C | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8267 | c.966G>C | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8270 | c.969G>C | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8276 | c.975G>A | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8283 | p.Ile328Leu | missense_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8288 | c.987T>C | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8294 | c.993T>C | synonymous_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8330 | c.1029C>G | synonymous_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8339 | c.1038A>G | synonymous_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8340 | p.Ala347Ser | missense_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8372 | c.1071G>C | synonymous_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8375 | c.1074G>C | synonymous_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8382 | p.Leu361Met | missense_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8387 | c.1086C>T | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8391 | p.Tyr364His | missense_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8399 | c.1098T>G | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8401 | p.Asp367Ala | missense_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8405 | c.1104C>T | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8420 | c.1119T>C | synonymous_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8442 | c.1141C>T | synonymous_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8453 | c.1152A>C | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8459 | c.1158G>A | synonymous_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8543 | c.1242C>G | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8546 | c.1245T>C | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8552 | c.1251C>A | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8561 | c.1260A>G | synonymous_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8576 | c.1275C>G | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8579 | c.1278C>T | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8588 | c.1287G>A | synonymous_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8597 | c.1296C>G | synonymous_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8603 | c.1302A>G | synonymous_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8619 | c.1318_1320delTTGinsCTA | synonymous_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8624 | c.1323G>C | synonymous_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8636 | c.1335A>C | synonymous_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8642 | c.1341A>G | synonymous_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8672 | c.1371A>G | synonymous_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8678 | c.1377G>A | synonymous_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8693 | c.1392T>C | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8696 | c.1395G>C | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8699 | c.1398A>G | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8711 | c.1410A>C | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8714 | c.1413A>G | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8780 | p.Asp493Glu | missense_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8837 | c.1536C>T | synonymous_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8852 | c.1551T>C | synonymous_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8858 | c.1557T>C | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8867 | c.1566A>G | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8873 | c.1572A>C | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8891 | c.1590G>A | synonymous_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8933 | c.1632G>C | synonymous_variant | 0.16 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8939 | c.1638T>C | synonymous_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8942 | c.1641G>C | synonymous_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8946 | c.1645_1647delTTGinsCTC | synonymous_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8966 | c.1665C>G | synonymous_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8967 | p.Ala556Arg | missense_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 0.15 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8990 | c.1689C>G | synonymous_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9017 | c.1716C>G | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9029 | c.1728T>C | synonymous_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9032 | c.1731T>C | synonymous_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9071 | c.1770G>C | synonymous_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9080 | c.1779G>T | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9089 | c.1788G>C | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9099 | c.1798_1800delTTAinsCTG | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9104 | c.1803C>G | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9119 | c.1818A>G | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9122 | c.1821C>G | synonymous_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9143 | c.1842T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9200 | c.1899A>G | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9204 | p.Ser635Thr | missense_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9224 | c.1923C>T | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9230 | c.1929T>C | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9233 | c.1932C>G | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9239 | c.1938C>T | synonymous_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9252 | p.Val651Ile | missense_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9284 | c.1983T>C | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9291 | c.1990C>T | synonymous_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9296 | c.1995T>C | synonymous_variant | 0.1 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9299 | c.1998G>C | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9300 | p.Ala667Ser | missense_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9308 | p.Asp669Glu | missense_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9323 | c.2022C>G | synonymous_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9335 | c.2034G>C | synonymous_variant | 0.11 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9566 | c.2265C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9771 | p.Asp824Asn | missense_variant | 0.27 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| fgd1 | 490782 | c.-1G>C | upstream_gene_variant | 0.13 | delamanid | |
| fgd1 | 490797 | c.15G>A | synonymous_variant | 0.13 | delamanid | |
| fgd1 | 490800 | c.18A>C | synonymous_variant | 0.14 | delamanid | |
| fgd1 | 490803 | c.21T>A | synonymous_variant | 0.14 | delamanid | |
| fgd1 | 490812 | c.30A>G | synonymous_variant | 0.16 | delamanid | |
| fgd1 | 490815 | c.33G>C | synonymous_variant | 0.16 | delamanid | |
| fgd1 | 490827 | c.45C>T | synonymous_variant | 0.16 | delamanid | |
| fgd1 | 490848 | c.66A>G | synonymous_variant | 0.16 | delamanid | |
| fgd1 | 490851 | c.69A>T | synonymous_variant | 0.16 | delamanid | |
| fgd1 | 490868 | p.Ala29Gly | missense_variant | 0.14 | delamanid | |
| fgd1 | 490887 | c.105G>A | synonymous_variant | 0.13 | delamanid | |
| fgd1 | 490890 | c.108C>G | synonymous_variant | 0.14 | delamanid | |
| fgd1 | 490896 | c.114C>T | synonymous_variant | 0.15 | delamanid | |
| fgd1 | 490905 | c.123T>C | synonymous_variant | 0.15 | delamanid | |
| fgd1 | 490911 | c.129T>G | synonymous_variant | 0.16 | delamanid | |
| fgd1 | 490917 | c.135C>G | synonymous_variant | 0.16 | delamanid | |
| fgd1 | 490921 | p.Gln47Glu | missense_variant | 0.15 | delamanid | |
| fgd1 | 490929 | c.147C>G | synonymous_variant | 0.14 | delamanid | |
| fgd1 | 490932 | c.150T>C | synonymous_variant | 0.14 | delamanid | |
| fgd1 | 490935 | c.153C>G | synonymous_variant | 0.13 | delamanid | |
| fgd1 | 490948 | p.Ser56Ala | missense_variant | 0.12 | delamanid | |
| fgd1 | 490998 | c.216T>C | synonymous_variant | 0.1 | delamanid | |
| fgd1 | 491007 | c.225G>C | synonymous_variant | 0.13 | delamanid | |
| fgd1 | 491013 | c.231C>G | synonymous_variant | 0.14 | delamanid | |
| fgd1 | 491043 | c.261T>G | synonymous_variant | 0.17 | delamanid | |
| fgd1 | 491049 | c.267T>C | synonymous_variant | 0.16 | delamanid | |
| fgd1 | 491063 | p.Gly94Ala | missense_variant | 0.12 | delamanid | |
| fgd1 | 491077 | p.Asn99Asp | missense_variant | 0.12 | delamanid | |
| fgd1 | 491082 | c.300T>C | synonymous_variant | 0.12 | delamanid | |
| fgd1 | 491083 | p.Val101Ile | missense_variant | 0.12 | delamanid | |
| fgd1 | 491091 | c.309T>C | synonymous_variant | 0.12 | delamanid | |
| fgd1 | 491094 | c.312C>G | synonymous_variant | 0.12 | delamanid | |
| fgd1 | 491097 | c.315G>C | synonymous_variant | 0.13 | delamanid | |
| fgd1 | 491100 | c.318C>T | synonymous_variant | 0.14 | delamanid | |
| fgd1 | 491106 | c.324T>C | synonymous_variant | 0.14 | delamanid | |
| fgd1 | 491121 | c.339A>G | synonymous_variant | 0.16 | delamanid | |
| fgd1 | 491130 | c.348C>G | synonymous_variant | 0.19 | delamanid | |
| fgd1 | 491144 | p.Ala121Asp | missense_variant | 0.19 | delamanid | |
| fgd1 | 491151 | c.369G>A | synonymous_variant | 0.19 | delamanid | |
| fgd1 | 491173 | c.391C>A | synonymous_variant | 0.17 | delamanid | |
| fgd1 | 491181 | c.399T>C | synonymous_variant | 0.15 | delamanid | |
| fgd1 | 491184 | c.402A>G | synonymous_variant | 0.15 | delamanid | |
| fgd1 | 491191 | p.Gly137Arg | missense_variant | 0.14 | delamanid | |
| fgd1 | 491194 | c.412_414delCTAinsTTG | synonymous_variant | 0.14 | delamanid | |
| fgd1 | 491202 | c.420G>C | synonymous_variant | 0.14 | delamanid | |
| fgd1 | 491203 | p.Gln141Glu | missense_variant | 0.15 | delamanid | |
| fgd1 | 491212 | p.Ser144Arg | missense_variant | 0.16 | delamanid | |
| fgd1 | 491217 | c.435T>C | synonymous_variant | 0.18 | delamanid | |
| fgd1 | 491232 | c.450T>C | synonymous_variant | 0.2 | delamanid | |
| fgd1 | 491241 | p.Asp153Glu | missense_variant | 0.2 | delamanid | |
| fgd1 | 491244 | c.462T>C | synonymous_variant | 0.21 | delamanid | |
| fgd1 | 491259 | c.477T>C | synonymous_variant | 0.2 | delamanid | |
| fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | delamanid | |
| mshA | 575809 | c.462C>T | synonymous_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| mshA | 575812 | c.465C>T | synonymous_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| mshA | 575824 | c.477T>G | synonymous_variant | 0.1 | ethionamide | |
| isoniazid | ||||||
| mshA | 575830 | c.483C>G | synonymous_variant | 0.1 | ethionamide | |
| isoniazid | ||||||
| mshA | 575833 | c.486C>G | synonymous_variant | 0.1 | ethionamide | |
| isoniazid | ||||||
| mshA | 575845 | c.498C>T | synonymous_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| ccsA | 620310 | c.420C>T | synonymous_variant | 0.1 | capreomycin | |
| amikacin | ||||||
| ccsA | 620317 | p.Val143Leu | missense_variant | 0.11 | capreomycin | |
| amikacin | Uncertain significance | |||||
| ccsA | 620340 | c.450C>G | synonymous_variant | 0.12 | capreomycin | |
| amikacin | ||||||
| ccsA | 620346 | c.456C>G | synonymous_variant | 0.12 | capreomycin | |
| amikacin | ||||||
| ccsA | 620362 | p.Ala158Thr | missense_variant | 0.11 | capreomycin | |
| amikacin | Uncertain significance | |||||
| ccsA | 620476 | p.Phe196Leu | missense_variant | 0.72 | capreomycin | |
| amikacin | ||||||
| rpoB | 760101 | c.295T>C | synonymous_variant | 0.11 | rifampicin | |
| rpoB | 760112 | c.306T>C | synonymous_variant | 0.11 | rifampicin | |
| rpoB | 760118 | c.312T>G | synonymous_variant | 0.11 | rifampicin | |
| rpoB | 760121 | c.315T>C | synonymous_variant | 0.12 | rifampicin | |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 0.13 | rifampicin | Uncertain significance |
| rpoB | 760139 | c.333A>G | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 760142 | c.336C>G | synonymous_variant | 0.13 | rifampicin | |
| rpoB | 760181 | c.375T>C | synonymous_variant | 0.12 | rifampicin | |
| rpoB | 760184 | c.378A>G | synonymous_variant | 0.12 | rifampicin | |
| rpoB | 760196 | c.390C>G | synonymous_variant | 0.13 | rifampicin | |
| rpoB | 760223 | c.417T>C | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 760283 | c.477G>C | synonymous_variant | 0.17 | rifampicin | |
| rpoB | 760298 | c.492G>C | synonymous_variant | 0.17 | rifampicin | |
| rpoB | 760307 | c.501T>C | synonymous_variant | 0.17 | rifampicin | |
| rpoB | 760310 | c.504G>C | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 760328 | c.522G>C | synonymous_variant | 0.19 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 0.19 | rifampicin | |
| rpoB | 760340 | c.534G>T | synonymous_variant | 0.21 | rifampicin | |
| rpoB | 760361 | c.555T>C | synonymous_variant | 0.2 | rifampicin | |
| rpoB | 760370 | c.564C>G | synonymous_variant | 0.19 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 0.18 | rifampicin | |
| rpoB | 760380 | p.Thr192Leu | missense_variant | 0.17 | rifampicin | |
| rpoB | 760406 | c.600G>C | synonymous_variant | 0.17 | rifampicin | |
| rpoB | 760412 | c.606C>G | synonymous_variant | 0.17 | rifampicin | |
| rpoB | 760424 | c.618C>G | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 760430 | c.624T>C | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 760475 | c.669A>G | synonymous_variant | 0.17 | rifampicin | |
| rpoB | 760481 | c.675G>C | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 760484 | c.678A>G | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 760522 | p.Ser239Asn | missense_variant | 0.15 | rifampicin | |
| rpoB | 760532 | c.726T>C | synonymous_variant | 0.13 | rifampicin | |
| rpoB | 760533 | p.Val243Thr | missense_variant | 0.13 | rifampicin | |
| rpoB | 760541 | c.735G>C | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 760547 | c.741G>C | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 760563 | p.Arg253Met | missense_variant | 0.16 | rifampicin | |
| rpoB | 760591 | p.Val262Ala | missense_variant | 0.17 | rifampicin | Uncertain significance |
| rpoB | 760611 | c.805T>C | synonymous_variant | 0.18 | rifampicin | |
| rpoB | 760646 | c.840C>G | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 760655 | c.849A>G | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 760661 | c.855A>C | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 760670 | c.864G>C | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 760674 | c.868T>C | synonymous_variant | 0.17 | rifampicin | |
| rpoB | 760679 | c.873A>G | synonymous_variant | 0.17 | rifampicin | |
| rpoB | 760683 | c.877T>C | synonymous_variant | 0.18 | rifampicin | |
| rpoB | 760715 | c.909C>G | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 760718 | c.912C>T | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 760724 | c.918T>C | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 760730 | c.924T>C | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 760751 | c.945G>C | synonymous_variant | 0.12 | rifampicin | |
| rpoB | 760757 | c.951T>C | synonymous_variant | 0.11 | rifampicin | |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 0.1 | rifampicin | |
| rpoB | 760934 | c.1128C>T | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 760949 | c.1143C>T | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 760982 | c.1176G>C | synonymous_variant | 0.18 | rifampicin | |
| rpoB | 760985 | c.1179G>C | synonymous_variant | 0.18 | rifampicin | |
| rpoB | 760991 | c.1185G>C | synonymous_variant | 0.18 | rifampicin | |
| rpoB | 761006 | c.1200C>G | synonymous_variant | 0.19 | rifampicin | |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 0.19 | rifampicin | |
| rpoB | 761021 | c.1215G>C | synonymous_variant | 0.19 | rifampicin | |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 0.19 | rifampicin | |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 0.2 | rifampicin | |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 0.19 | rifampicin | |
| rpoB | 761057 | c.1251G>C | synonymous_variant | 0.19 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 0.21 | rifampicin | |
| rpoB | 761129 | c.1323G>C | synonymous_variant | 0.22 | rifampicin | |
| rpoB | 761132 | c.1326G>T | synonymous_variant | 0.22 | rifampicin | |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 0.23 | rifampicin | |
| rpoB | 761150 | c.1344A>C | synonymous_variant | 0.24 | rifampicin | |
| rpoB | 761153 | c.1347G>C | synonymous_variant | 0.23 | rifampicin | |
| rpoB | 761165 | c.1359G>C | synonymous_variant | 0.21 | rifampicin | |
| rpoB | 761180 | c.1374A>C | synonymous_variant | 0.21 | rifampicin | |
| rpoB | 761189 | c.1383T>C | synonymous_variant | 0.21 | rifampicin | |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 0.21 | rifampicin | |
| rpoB | 761207 | c.1401C>T | synonymous_variant | 0.21 | rifampicin | |
| rpoB | 761213 | c.1407G>C | synonymous_variant | 0.21 | rifampicin | |
| rpoB | 761219 | c.1413G>C | synonymous_variant | 0.2 | rifampicin | |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 0.2 | rifampicin | |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 0.19 | rifampicin | |
| rpoB | 761261 | c.1455G>T | synonymous_variant | 0.18 | rifampicin | |
| rpoB | 761306 | c.1500C>G | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 761312 | c.1506G>C | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 761330 | c.1524G>C | synonymous_variant | 0.13 | rifampicin | |
| rpoB | 761354 | c.1548C>T | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 761360 | c.1554T>C | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 761362 | p.Ser519Thr | missense_variant | 0.15 | rifampicin | |
| rpoB | 761373 | p.Val523His | missense_variant | 0.13 | rifampicin | |
| rpoB | 761408 | c.1602G>C | synonymous_variant | 0.19 | rifampicin | |
| rpoB | 761414 | c.1608A>G | synonymous_variant | 0.19 | rifampicin | |
| rpoB | 761423 | c.1617T>C | synonymous_variant | 0.19 | rifampicin | |
| rpoB | 761435 | c.1629T>C | synonymous_variant | 0.19 | rifampicin | |
| rpoB | 761438 | c.1632G>C | synonymous_variant | 0.17 | rifampicin | |
| rpoB | 761439 | p.Asp545Lys | missense_variant | 0.17 | rifampicin | |
| rpoB | 761444 | c.1638T>C | synonymous_variant | 0.18 | rifampicin | |
| rpoB | 761447 | c.1641C>G | synonymous_variant | 0.18 | rifampicin | |
| rpoB | 761452 | p.Val549Glu | missense_variant | 0.17 | rifampicin | |
| rpoB | 761457 | p.Pro551Ser | missense_variant | 0.18 | rifampicin | |
| rpoB | 761477 | c.1671C>G | synonymous_variant | 0.18 | rifampicin | |
| rpoB | 761492 | c.1686G>C | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 761510 | c.1704T>C | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 0.13 | rifampicin | |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 761588 | c.1782C>T | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 761612 | c.1806G>C | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 0.13 | rifampicin | |
| rpoB | 761639 | c.1833G>A | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 0.13 | rifampicin | |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 0.13 | rifampicin | |
| rpoB | 761657 | c.1851C>G | synonymous_variant | 0.12 | rifampicin | |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 0.11 | rifampicin | |
| rpoB | 761727 | p.Ser641Gly | missense_variant | 0.14 | rifampicin | |
| rpoB | 761728 | c.1923dupC | frameshift_variant | 0.14 | rifampicin | |
| rpoB | 761732 | c.1926C>G | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 761735 | c.1929C>G | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 761747 | c.1941G>C | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 761765 | c.1959T>C | synonymous_variant | 0.11 | rifampicin | |
| rpoB | 762008 | c.2202C>T | synonymous_variant | 0.1 | rifampicin | |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 0.12 | rifampicin | |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 762114 | p.Ile770Val | missense_variant | 0.15 | rifampicin | |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 762140 | c.2334G>C | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 0.14 | rifampicin | |
| rpoB | 762149 | c.2343G>C | synonymous_variant | 0.13 | rifampicin | |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 762176 | c.2370T>C | synonymous_variant | 0.17 | rifampicin | |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 0.18 | rifampicin | |
| rpoB | 762206 | c.2400C>G | synonymous_variant | 0.2 | rifampicin | |
| rpoB | 762233 | c.2427G>C | synonymous_variant | 0.19 | rifampicin | |
| rpoB | 762246 | c.2440C>T | synonymous_variant | 0.18 | rifampicin | |
| rpoB | 762254 | c.2448T>G | synonymous_variant | 0.17 | rifampicin | |
| rpoB | 762257 | c.2451C>G | synonymous_variant | 0.15 | rifampicin | |
| rpoB | 762266 | c.2460T>C | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 762314 | c.2508C>T | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 762329 | c.2523G>C | synonymous_variant | 0.17 | rifampicin | |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 0.17 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 0.16 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 0.14 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.16 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.16 | rifampicin | |
| rpoC | 762404 | c.-966T>C | upstream_gene_variant | 0.16 | rifampicin | |
| rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.18 | rifampicin | |
| rpoC | 762416 | c.-954A>G | upstream_gene_variant | 0.18 | rifampicin | |
| rpoC | 762419 | c.-951C>G | upstream_gene_variant | 0.18 | rifampicin | |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 0.2 | rifampicin | |
| rpoC | 762449 | c.-921C>A | upstream_gene_variant | 0.21 | rifampicin | |
| rpoC | 762467 | c.-903C>T | upstream_gene_variant | 0.19 | rifampicin | |
| rpoC | 762488 | c.-882G>C | upstream_gene_variant | 0.18 | rifampicin | |
| rpoB | 762489 | p.Val895Gln | missense_variant | 0.18 | rifampicin | |
| rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.18 | rifampicin | |
| rpoB | 762510 | p.Ala902Pro | missense_variant | 0.18 | rifampicin | Uncertain significance |
| rpoC | 762521 | c.-849C>T | upstream_gene_variant | 0.19 | rifampicin | |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.11 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.1 | rifampicin | |
| rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.1 | rifampicin | |
| rpoC | 762551 | c.-819C>G | upstream_gene_variant | 0.11 | rifampicin | |
| rpoC | 762758 | c.-612G>C | upstream_gene_variant | 0.1 | rifampicin | |
| rpoC | 762782 | c.-588T>C | upstream_gene_variant | 0.14 | rifampicin | |
| rpoB | 762785 | p.Asp993Glu | missense_variant | 0.14 | rifampicin | |
| rpoC | 762788 | c.-582G>C | upstream_gene_variant | 0.14 | rifampicin | |
| rpoB | 762789 | p.Leu995Met | missense_variant | 0.14 | rifampicin | |
| rpoC | 762794 | c.-576C>G | upstream_gene_variant | 0.15 | rifampicin | |
| rpoB | 762799 | p.Ala998Gly | missense_variant | 0.16 | rifampicin | |
| rpoB | 762810 | p.Ala1002Ser | missense_variant | 0.16 | rifampicin | |
| rpoB | 762813 | p.Met1003Val | missense_variant | 0.16 | rifampicin | |
| rpoC | 762818 | c.-552C>G | upstream_gene_variant | 0.17 | rifampicin | |
| rpoC | 762827 | c.-543G>C | upstream_gene_variant | 0.17 | rifampicin | |
| rpoC | 762857 | c.-513C>G | upstream_gene_variant | 0.19 | rifampicin | |
| rpoC | 762860 | c.-510G>C | upstream_gene_variant | 0.18 | rifampicin | |
| rpoC | 762863 | c.-507T>C | upstream_gene_variant | 0.18 | rifampicin | |
| rpoC | 762929 | c.-441G>C | upstream_gene_variant | 0.21 | rifampicin | |
| rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.23 | rifampicin | |
| rpoC | 763013 | c.-357C>G | upstream_gene_variant | 0.24 | rifampicin | |
| rpoC | 763028 | c.-342T>C | upstream_gene_variant | 0.22 | rifampicin | |
| rpoC | 763031 | c.-339T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763034 | c.-336C>G | upstream_gene_variant | 0.24 | rifampicin | |
| rpoC | 763040 | c.-330C>G | upstream_gene_variant | 0.23 | rifampicin | |
| rpoC | 763070 | c.-300T>C | upstream_gene_variant | 0.22 | rifampicin | |
| rpoC | 763085 | c.-285C>G | upstream_gene_variant | 0.22 | rifampicin | |
| rpoC | 763115 | c.-255T>C | upstream_gene_variant | 0.2 | rifampicin | |
| rpoC | 763136 | c.-234C>T | upstream_gene_variant | 0.22 | rifampicin | |
| rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.2 | rifampicin | |
| rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.19 | rifampicin | |
| rpoC | 763166 | c.-204A>G | upstream_gene_variant | 0.18 | rifampicin | |
| rpoC | 763190 | c.-180C>T | upstream_gene_variant | 0.15 | rifampicin | |
| rpoC | 763202 | c.-168A>G | upstream_gene_variant | 0.11 | rifampicin | |
| rpoC | 763205 | c.-165G>C | upstream_gene_variant | 0.1 | rifampicin | |
| rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 0.1 | rifampicin | |
| rpoC | 763214 | c.-156T>C | upstream_gene_variant | 0.1 | rifampicin | |
| rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.1 | rifampicin | |
| rpoC | 763227 | c.-143C>T | upstream_gene_variant | 0.1 | rifampicin | |
| rpoC | 763238 | c.-132T>C | upstream_gene_variant | 0.1 | rifampicin | |
| rpoC | 763402 | c.33C>G | synonymous_variant | 0.11 | rifampicin | |
| rpoC | 763411 | c.42T>G | synonymous_variant | 0.11 | rifampicin | |
| rpoC | 763414 | c.45T>C | synonymous_variant | 0.12 | rifampicin | |
| rpoC | 763441 | c.72C>T | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 763444 | c.75T>C | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 763456 | c.87A>G | synonymous_variant | 0.17 | rifampicin | |
| rpoC | 763486 | c.117T>G | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 763528 | c.159G>A | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 763546 | c.177A>G | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 763570 | c.201G>C | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 763573 | c.204G>C | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 763594 | c.225C>T | synonymous_variant | 0.24 | rifampicin | |
| rpoC | 763633 | c.264T>C | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 763636 | c.267T>C | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 763660 | c.291T>G | synonymous_variant | 0.23 | rifampicin | |
| rpoC | 763675 | c.306C>G | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 763696 | c.327T>C | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 763702 | c.333C>G | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 763717 | c.348T>C | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 763723 | c.354G>C | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 763732 | c.363C>G | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 763741 | c.372C>T | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 763744 | c.375G>C | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 763765 | c.396T>C | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 763774 | c.405G>C | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 763816 | c.447C>G | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 763835 | p.Ala156Met | missense_variant | 0.16 | rifampicin | |
| rpoC | 763853 | p.Val162Ile | missense_variant | 0.15 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 0.15 | rifampicin | |
| rpoC | 763872 | p.Gly168Ala | missense_variant | 0.12 | rifampicin | |
| rpoC | 763876 | p.Glu169Asp | missense_variant | 0.11 | rifampicin | |
| rpoC | 763877 | c.508_510delCTAinsTTG | synonymous_variant | 0.1 | rifampicin | |
| rpoC | 763888 | c.519G>C | synonymous_variant | 0.11 | rifampicin | |
| rpoC | 763891 | c.522G>C | synonymous_variant | 0.11 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 0.12 | rifampicin | |
| rpoC | 763900 | c.531G>C | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 763936 | c.567C>G | synonymous_variant | 0.12 | rifampicin | |
| rpoC | 763945 | c.576T>C | synonymous_variant | 0.13 | rifampicin | |
| rpoC | 763951 | c.582G>C | synonymous_variant | 0.13 | rifampicin | |
| rpoC | 763960 | c.591T>C | synonymous_variant | 0.13 | rifampicin | |
| rpoC | 764002 | c.633C>G | synonymous_variant | 0.11 | rifampicin | |
| rpoC | 764005 | c.636G>C | synonymous_variant | 0.11 | rifampicin | |
| rpoC | 764024 | c.655_657delTTGinsCTC | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 764032 | p.Asp221Glu | missense_variant | 0.14 | rifampicin | |
| rpoC | 764040 | p.Ser224Thr | missense_variant | 0.14 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 764059 | c.690G>T | synonymous_variant | 0.16 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 0.16 | rifampicin | |
| rpoC | 764098 | c.729A>G | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 764101 | c.732C>G | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 764102 | p.Val245Ile | missense_variant | 0.14 | rifampicin | |
| rpoC | 764112 | p.Tyr248Phe | missense_variant | 0.14 | rifampicin | |
| rpoC | 764116 | c.747C>T | synonymous_variant | 0.15 | rifampicin | |
| rpoC | 764131 | c.762T>C | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 764140 | c.771C>T | synonymous_variant | 0.15 | rifampicin | |
| rpoC | 764188 | c.819A>G | synonymous_variant | 0.16 | rifampicin | |
| rpoC | 764195 | p.Ser276Ile | missense_variant | 0.14 | rifampicin | |
| rpoC | 764203 | c.834G>C | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 764206 | c.837T>C | synonymous_variant | 0.15 | rifampicin | |
| rpoC | 764215 | c.846A>G | synonymous_variant | 0.16 | rifampicin | |
| rpoC | 764236 | c.867G>A | synonymous_variant | 0.17 | rifampicin | |
| rpoC | 764248 | c.879C>G | synonymous_variant | 0.17 | rifampicin | |
| rpoC | 764257 | c.888G>C | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 764266 | c.897T>C | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 764269 | c.900G>C | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 764272 | c.903G>C | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 764338 | c.969G>A | synonymous_variant | 0.28 | rifampicin | |
| rpoC | 764353 | c.984G>C | synonymous_variant | 0.32 | rifampicin | |
| rpoC | 764365 | c.996C>T | synonymous_variant | 0.28 | rifampicin | |
| rpoC | 764380 | c.1011G>C | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 764405 | c.1036A>C | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 764419 | c.1050C>G | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 764428 | c.1059G>C | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 764431 | c.1062G>C | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 0.16 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 0.15 | rifampicin | |
| rpoC | 764452 | c.1083T>C | synonymous_variant | 0.16 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 764489 | c.1120C>T | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 764510 | c.1141C>T | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 764527 | c.1158C>T | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 764536 | c.1167G>C | synonymous_variant | 0.23 | rifampicin | |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 0.25 | rifampicin | |
| rpoC | 764554 | c.1185C>T | synonymous_variant | 0.3 | rifampicin | |
| rpoC | 764560 | c.1191T>C | synonymous_variant | 0.29 | rifampicin | |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 0.28 | rifampicin | |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 0.27 | rifampicin | |
| rpoC | 764581 | c.1212T>C | synonymous_variant | 0.28 | rifampicin | |
| rpoC | 764593 | c.1224C>T | synonymous_variant | 0.28 | rifampicin | |
| rpoC | 764611 | c.1242G>T | synonymous_variant | 0.27 | rifampicin | |
| rpoC | 764650 | c.1281G>C | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 0.24 | rifampicin | |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 0.25 | rifampicin | |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 0.26 | rifampicin | |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 0.26 | rifampicin | |
| rpoC | 764827 | c.1458G>C | synonymous_variant | 0.25 | rifampicin | |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 0.23 | rifampicin | |
| rpoC | 764872 | c.1503A>G | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 0.17 | rifampicin | |
| rpoC | 764932 | c.1563C>A | synonymous_variant | 0.15 | rifampicin | |
| rpoC | 764935 | c.1566T>C | synonymous_variant | 0.15 | rifampicin | |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 0.15 | rifampicin | |
| rpoC | 764995 | c.1626C>G | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 765034 | c.1665T>C | synonymous_variant | 0.17 | rifampicin | |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 0.16 | rifampicin | |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 0.16 | rifampicin | |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 0.16 | rifampicin | |
| rpoC | 765053 | c.1684_1685delTCinsAG | synonymous_variant | 0.16 | rifampicin | |
| rpoC | 765073 | c.1704G>C | synonymous_variant | 0.15 | rifampicin | |
| rpoC | 765076 | c.1707A>G | synonymous_variant | 0.15 | rifampicin | |
| rpoC | 765079 | c.1710T>G | synonymous_variant | 0.15 | rifampicin | |
| rpoC | 765082 | c.1713G>C | synonymous_variant | 0.15 | rifampicin | |
| rpoC | 765089 | c.1720T>C | synonymous_variant | 0.15 | rifampicin | |
| rpoC | 765103 | c.1734G>T | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 765319 | c.1950A>G | synonymous_variant | 0.11 | rifampicin | |
| rpoC | 765326 | p.His653Ala | missense_variant | 0.11 | rifampicin | |
| rpoC | 765329 | p.Ser654Gly | missense_variant | 0.11 | rifampicin | |
| rpoC | 765346 | c.1977C>G | synonymous_variant | 0.13 | rifampicin | |
| rpoC | 765349 | c.1980T>C | synonymous_variant | 0.13 | rifampicin | |
| rpoC | 765352 | c.1983G>C | synonymous_variant | 0.13 | rifampicin | |
| rpoC | 765383 | p.Met672Leu | missense_variant | 0.17 | rifampicin | |
| rpoC | 765404 | p.Leu679Val | missense_variant | 0.18 | rifampicin | |
| rpoC | 765409 | c.2040T>C | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 765421 | c.2052C>G | synonymous_variant | 0.17 | rifampicin | |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 765529 | c.2160C>T | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 765541 | c.2172C>G | synonymous_variant | 0.23 | rifampicin | |
| rpoC | 765553 | c.2184C>T | synonymous_variant | 0.23 | rifampicin | |
| rpoC | 765556 | c.2187G>C | synonymous_variant | 0.23 | rifampicin | |
| rpoC | 765559 | c.2190G>C | synonymous_variant | 0.23 | rifampicin | |
| rpoC | 765580 | c.2211G>C | synonymous_variant | 0.24 | rifampicin | |
| rpoC | 765613 | p.His748Gln | missense_variant | 0.24 | rifampicin | |
| rpoC | 765625 | c.2256C>G | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 765631 | p.Asp754Glu | missense_variant | 0.22 | rifampicin | |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 765739 | c.2370G>T | synonymous_variant | 0.23 | rifampicin | |
| rpoC | 765751 | c.2382C>G | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 765753 | p.Asp795Ala | missense_variant | 0.21 | rifampicin | |
| rpoC | 765772 | c.2403C>G | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 765784 | c.2415C>G | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 765814 | c.2445A>G | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 765850 | c.2481G>C | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 765883 | c.2514C>G | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 765892 | c.2523T>C | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 765937 | c.2568T>C | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 765982 | c.2613C>G | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 766021 | c.2652G>C | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 766027 | c.2658G>C | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 766030 | c.2661C>G | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 766036 | c.2667C>T | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 766043 | p.Gln892Glu | missense_variant | 0.19 | rifampicin | |
| rpoC | 766054 | c.2685C>G | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 766082 | p.Ala905Gln | missense_variant | 0.18 | rifampicin | |
| rpoC | 766096 | c.2727G>C | synonymous_variant | 0.16 | rifampicin | |
| rpoC | 766129 | c.2760C>G | synonymous_variant | 0.13 | rifampicin | |
| rpoC | 766135 | c.2766G>A | synonymous_variant | 0.12 | rifampicin | |
| rpoC | 766141 | c.2772C>T | synonymous_variant | 0.1 | rifampicin | |
| rpoC | 766142 | c.2773C>T | synonymous_variant | 0.1 | rifampicin | |
| rpoC | 766312 | c.2943T>G | synonymous_variant | 0.12 | rifampicin | |
| rpoC | 766327 | c.2958C>A | synonymous_variant | 0.13 | rifampicin | |
| rpoC | 766345 | c.2976T>C | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 766348 | c.2979A>G | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 766357 | c.2988C>T | synonymous_variant | 0.15 | rifampicin | |
| rpoC | 766363 | c.2994G>C | synonymous_variant | 0.16 | rifampicin | |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 766408 | c.3039C>G | synonymous_variant | 0.17 | rifampicin | |
| rpoC | 766411 | c.3042C>G | synonymous_variant | 0.18 | rifampicin | |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 766447 | c.3078T>C | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 766462 | c.3093G>C | synonymous_variant | 0.16 | rifampicin | |
| rpoC | 766483 | c.3114G>C | synonymous_variant | 0.12 | rifampicin | |
| rpoC | 766484 | p.Val1039Ile | missense_variant | 0.12 | rifampicin | |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 0.13 | rifampicin | |
| rpoC | 766522 | c.3153C>G | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 766528 | c.3159T>C | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 766531 | c.3162G>C | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 766540 | p.Asp1057Glu | missense_variant | 0.13 | rifampicin | |
| rpoC | 766549 | c.3180G>C | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 0.11 | rifampicin | |
| rpoC | 766582 | c.3213C>G | synonymous_variant | 0.1 | rifampicin | |
| rpoC | 766583 | p.Gly1072Ser | missense_variant | 0.1 | rifampicin | |
| rpoC | 766591 | c.3222A>G | synonymous_variant | 0.1 | rifampicin | |
| rpoC | 766594 | c.3225G>C | synonymous_variant | 0.11 | rifampicin | |
| rpoC | 766597 | c.3228C>G | synonymous_variant | 0.11 | rifampicin | |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.13 | rifampicin | |
| rpoC | 766630 | c.3261G>C | synonymous_variant | 0.16 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 766673 | p.Gly1102Asn | missense_variant | 0.18 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 0.23 | rifampicin | |
| rpoC | 766801 | c.3432C>G | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 766861 | c.3492G>C | synonymous_variant | 0.23 | rifampicin | |
| rpoC | 766864 | c.3495G>C | synonymous_variant | 0.24 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 0.26 | rifampicin | |
| rpoC | 766933 | c.3564A>G | synonymous_variant | 0.29 | rifampicin | |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 0.3 | rifampicin | |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 0.27 | rifampicin | |
| rpoC | 766972 | c.3603G>C | synonymous_variant | 0.24 | rifampicin | |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 0.25 | rifampicin | |
| rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 767014 | c.3645G>C | synonymous_variant | 0.22 | rifampicin | |
| rpoC | 767033 | c.3664_3666delTCGinsAGC | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 767062 | c.3693C>A | synonymous_variant | 0.21 | rifampicin | |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 0.19 | rifampicin | |
| rpoC | 767134 | c.3765C>A | synonymous_variant | 0.16 | rifampicin | |
| rpoC | 767158 | c.3789T>C | synonymous_variant | 0.16 | rifampicin | |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.15 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 0.13 | rifampicin | |
| rpoC | 767212 | c.3843G>C | synonymous_variant | 0.13 | rifampicin | |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 0.13 | rifampicin | |
| rpoC | 767230 | c.3861G>C | synonymous_variant | 0.12 | rifampicin | |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 0.11 | rifampicin | |
| mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775753 | c.2727delC | frameshift_variant | 0.25 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Uncertain significance |
| rpsL | 781628 | c.69T>C | synonymous_variant | 0.11 | streptomycin | |
| rpsL | 781631 | c.72G>C | synonymous_variant | 0.13 | streptomycin | |
| rpsL | 781649 | c.90T>C | synonymous_variant | 0.17 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 0.16 | streptomycin | |
| rpsL | 781700 | c.141G>C | synonymous_variant | 0.2 | streptomycin | |
| rpsL | 781703 | c.144G>T | synonymous_variant | 0.2 | streptomycin | |
| rpsL | 781715 | c.156T>C | synonymous_variant | 0.22 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 0.22 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 0.21 | streptomycin | |
| rpsL | 781742 | c.183C>T | synonymous_variant | 0.22 | streptomycin | |
| rpsL | 781748 | c.189C>G | synonymous_variant | 0.23 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 0.23 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 0.23 | streptomycin | |
| rpsL | 781772 | c.213C>A | synonymous_variant | 0.21 | streptomycin | |
| rpsL | 781808 | c.249C>T | synonymous_variant | 0.2 | streptomycin | |
| rpsL | 781811 | c.252C>T | synonymous_variant | 0.19 | streptomycin | |
| rpsL | 781832 | c.273T>C | synonymous_variant | 0.18 | streptomycin | |
| rpsL | 781838 | c.279G>C | synonymous_variant | 0.18 | streptomycin | |
| rpsL | 781841 | c.282C>G | synonymous_variant | 0.17 | streptomycin | |
| rpsL | 781865 | c.306G>C | synonymous_variant | 0.17 | streptomycin | |
| rpsL | 781868 | c.309T>C | synonymous_variant | 0.16 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 0.16 | streptomycin | |
| rpsL | 781877 | c.318T>C | synonymous_variant | 0.15 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 0.15 | streptomycin | |
| rpsL | 781898 | c.339A>T | synonymous_variant | 0.16 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 0.17 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 0.19 | streptomycin | Uncertain significance |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.15 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.16 | linezolid | Uncertain significance |
| rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.16 | linezolid | |
| rplC | 800648 | c.-161A>T | upstream_gene_variant | 0.19 | linezolid | |
| rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.19 | linezolid | |
| rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.18 | linezolid | |
| rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.16 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.15 | linezolid | |
| rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.15 | linezolid | |
| rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.15 | linezolid | |
| rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.13 | linezolid | |
| rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.14 | linezolid | |
| rplC | 800793 | c.-16G>C | upstream_gene_variant | 0.61 | linezolid | Uncertain significance |
| rplC | 800794 | c.-15A>G | upstream_gene_variant | 0.1 | linezolid | |
| rplC | 801246 | c.438C>T | synonymous_variant | 0.12 | linezolid | |
| rplC | 801255 | c.447C>T | synonymous_variant | 0.12 | linezolid | |
| rplC | 801264 | c.456C>T | synonymous_variant | 0.11 | linezolid | |
| rplC | 801267 | c.459A>T | synonymous_variant | 0.11 | linezolid | |
| rplC | 801270 | c.462T>C | synonymous_variant | 0.1 | linezolid | |
| rplC | 801276 | c.468G>C | synonymous_variant | 0.1 | linezolid | |
| rplC | 801279 | c.471G>A | synonymous_variant | 0.1 | linezolid | |
| rplC | 801300 | c.492C>G | synonymous_variant | 0.11 | linezolid | |
| rplC | 801309 | c.501C>G | synonymous_variant | 0.13 | linezolid | |
| rplC | 801312 | c.504G>C | synonymous_variant | 0.13 | linezolid | |
| rplC | 801321 | c.513C>T | synonymous_variant | 0.14 | linezolid | |
| rplC | 801324 | c.516T>C | synonymous_variant | 0.14 | linezolid | |
| rplC | 801339 | c.531T>C | synonymous_variant | 0.12 | linezolid | |
| rplC | 801341 | p.Leu178Gln | missense_variant | 0.12 | linezolid | |
| rplC | 801348 | c.540T>G | synonymous_variant | 0.13 | linezolid | |
| rplC | 801357 | c.549T>C | synonymous_variant | 0.14 | linezolid | |
| rplC | 801367 | p.Ala187Thr | missense_variant | 0.14 | linezolid | |
| rplC | 801402 | c.594T>C | synonymous_variant | 0.12 | linezolid | |
| rplC | 801405 | c.597T>C | synonymous_variant | 0.12 | linezolid | |
| rplC | 801423 | c.615G>C | synonymous_variant | 0.11 | linezolid | |
| rplC | 801426 | c.618C>G | synonymous_variant | 0.1 | linezolid | |
| rplC | 801427 | p.Met207Val | missense_variant | 0.1 | linezolid | |
| rplC | 801438 | c.630T>C | synonymous_variant | 0.11 | linezolid | |
| rplC | 801442 | p.Ile212Val | missense_variant | 0.12 | linezolid | |
| fbiC | 1302899 | c.-32A>G | upstream_gene_variant | 1.0 | delamanid | Uncertain significance |
| fbiC | 1303545 | c.615A>G | synonymous_variant | 0.1 | delamanid | |
| fbiC | 1303590 | c.660A>G | synonymous_variant | 0.1 | delamanid | |
| fbiC | 1303746 | c.816T>C | synonymous_variant | 0.1 | delamanid | |
| fbiC | 1303749 | c.819G>C | synonymous_variant | 0.1 | delamanid | |
| fbiC | 1303752 | c.822A>G | synonymous_variant | 0.1 | delamanid | |
| fbiC | 1303755 | c.825T>C | synonymous_variant | 0.1 | delamanid | |
| fbiC | 1303761 | c.831T>C | synonymous_variant | 0.11 | delamanid | |
| fbiC | 1303785 | c.855G>C | synonymous_variant | 0.12 | delamanid | |
| fbiC | 1303789 | p.Ile287Val | missense_variant | 0.11 | delamanid | |
| fbiC | 1303797 | c.867A>G | synonymous_variant | 0.13 | delamanid | |
| fbiC | 1303818 | c.888C>G | synonymous_variant | 0.15 | delamanid | |
| fbiC | 1303836 | c.906G>C | synonymous_variant | 0.14 | delamanid | |
| fbiC | 1303845 | c.915C>G | synonymous_variant | 0.13 | delamanid | |
| fbiC | 1303846 | p.Phe306Val | missense_variant | 0.13 | delamanid | |
| fbiC | 1303854 | c.924T>C | synonymous_variant | 0.13 | delamanid | |
| fbiC | 1303860 | c.930A>C | synonymous_variant | 0.13 | delamanid | |
| fbiC | 1303884 | c.954T>G | synonymous_variant | 0.15 | delamanid | |
| fbiC | 1303905 | c.975G>C | synonymous_variant | 0.14 | delamanid | |
| fbiC | 1303914 | c.984C>G | synonymous_variant | 0.14 | delamanid | |
| fbiC | 1303920 | c.990C>T | synonymous_variant | 0.12 | delamanid | |
| fbiC | 1303961 | p.Arg344Leu | missense_variant | 0.1 | delamanid | |
| fbiC | 1303971 | c.1041T>C | synonymous_variant | 0.11 | delamanid | |
| fbiC | 1303980 | c.1050G>A | synonymous_variant | 0.12 | delamanid | |
| fbiC | 1304004 | c.1074A>G | synonymous_variant | 0.12 | delamanid | |
| fbiC | 1304008 | c.1078T>C | synonymous_variant | 0.13 | delamanid | |
| fbiC | 1304022 | c.1092T>C | synonymous_variant | 0.1 | delamanid | |
| fbiC | 1304724 | c.1794A>G | synonymous_variant | 0.1 | delamanid | |
| fbiC | 1304727 | c.1797A>G | synonymous_variant | 0.11 | delamanid | |
| fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.11 | delamanid | |
| fbiC | 1304748 | c.1818T>C | synonymous_variant | 0.12 | delamanid | |
| fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.12 | delamanid | |
| fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.13 | delamanid | |
| fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.13 | delamanid | |
| fbiC | 1304787 | c.1857T>G | synonymous_variant | 0.13 | delamanid | |
| fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.14 | delamanid | |
| fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.13 | delamanid | |
| fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.17 | delamanid | |
| fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.17 | delamanid | |
| fbiC | 1304832 | c.1902C>T | synonymous_variant | 0.18 | delamanid | |
| fbiC | 1304853 | c.1923C>T | synonymous_variant | 0.21 | delamanid | |
| fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.21 | delamanid | |
| fbiC | 1304869 | c.1939C>T | synonymous_variant | 0.23 | delamanid | |
| fbiC | 1304875 | p.Ile649Val | missense_variant | 0.22 | delamanid | |
| fbiC | 1304883 | p.Glu651Asp | missense_variant | 0.23 | delamanid | |
| fbiC | 1304891 | p.Ile654Thr | missense_variant | 0.24 | delamanid | |
| fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.24 | delamanid | |
| fbiC | 1304907 | c.1977C>G | synonymous_variant | 0.25 | delamanid | |
| fbiC | 1304910 | c.1980G>C | synonymous_variant | 0.27 | delamanid | |
| fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.28 | delamanid | |
| fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.3 | delamanid | |
| fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.3 | delamanid | |
| fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.3 | delamanid | |
| fbiC | 1304983 | c.2053C>T | synonymous_variant | 0.3 | delamanid | |
| fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.29 | delamanid | |
| fbiC | 1304995 | p.Leu689Met | missense_variant | 0.29 | delamanid | |
| fbiC | 1305006 | c.2076A>G | synonymous_variant | 0.26 | delamanid | |
| fbiC | 1305012 | c.2082G>C | synonymous_variant | 0.24 | delamanid | |
| fbiC | 1305015 | c.2085G>C | synonymous_variant | 0.24 | delamanid | |
| fbiC | 1305021 | c.2091C>G | synonymous_variant | 0.23 | delamanid | |
| fbiC | 1305030 | c.2100G>C | synonymous_variant | 0.21 | delamanid | |
| fbiC | 1305033 | c.2103T>G | synonymous_variant | 0.21 | delamanid | |
| fbiC | 1305042 | c.2112A>G | synonymous_variant | 0.23 | delamanid | |
| fbiC | 1305063 | c.2133G>C | synonymous_variant | 0.17 | delamanid | |
| fbiC | 1305066 | c.2136T>C | synonymous_variant | 0.15 | delamanid | |
| fbiC | 1305069 | c.2139G>C | synonymous_variant | 0.14 | delamanid | |
| fbiC | 1305075 | c.2145T>C | synonymous_variant | 0.13 | delamanid | |
| fbiC | 1305078 | c.2148A>G | synonymous_variant | 0.13 | delamanid | |
| fbiC | 1305081 | c.2151G>C | synonymous_variant | 0.13 | delamanid | |
| fbiC | 1305090 | c.2160C>G | synonymous_variant | 0.13 | delamanid | |
| fbiC | 1305092 | p.Ala721Gly | missense_variant | 0.12 | delamanid | |
| fbiC | 1305099 | c.2169T>C | synonymous_variant | 0.11 | delamanid | |
| atpE | 1461149 | c.105T>G | synonymous_variant | 0.1 | bedaquiline | |
| rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.1 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.21 | linezolid | |
| rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.19 | linezolid | Uncertain significance |
| rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1473945 | n.288T>A | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| rrl | 1473946 | n.289A>T | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 0.18 | linezolid | Uncertain significance |
| rrl | 1473987 | n.330G>A | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.19 | linezolid | Uncertain significance |
| rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1474093 | n.436G>T | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| rrl | 1474099 | n.442G>A | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1474291 | n.635_649delTTCCTCTCCGGAGGA | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1474376 | n.719T>C | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1474409 | n.756_766delACCCACACGCG | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1474427 | n.770A>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1474429 | n.772G>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1474435 | n.780_783delGAAT | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.24 | linezolid | Uncertain significance |
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.22 | linezolid | |
| rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1474904 | n.1247G>A | non_coding_transcript_exon_variant | 0.24 | linezolid | |
| rrl | 1474956 | n.1299C>T | non_coding_transcript_exon_variant | 0.22 | linezolid | |
| rrl | 1474960 | n.1303C>G | non_coding_transcript_exon_variant | 0.23 | linezolid | |
| rrl | 1474963 | n.1306G>T | non_coding_transcript_exon_variant | 0.23 | linezolid | |
| rrl | 1474964 | n.1307T>A | non_coding_transcript_exon_variant | 0.23 | linezolid | |
| rrl | 1474965 | n.1308G>C | non_coding_transcript_exon_variant | 0.23 | linezolid | |
| rrl | 1474970 | n.1313G>A | non_coding_transcript_exon_variant | 0.24 | linezolid | |
| rrl | 1475006 | n.1349A>T | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 0.22 | linezolid | |
| rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 0.22 | linezolid | |
| rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 0.26 | linezolid | |
| rrl | 1475206 | n.1549C>T | non_coding_transcript_exon_variant | 0.24 | linezolid | |
| rrl | 1475209 | n.1552G>C | non_coding_transcript_exon_variant | 0.23 | linezolid | |
| rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 0.24 | linezolid | |
| rrl | 1475249 | n.1592T>C | non_coding_transcript_exon_variant | 0.23 | linezolid | Uncertain significance |
| rrl | 1475252 | n.1595C>T | non_coding_transcript_exon_variant | 0.23 | linezolid | |
| rrl | 1475266 | n.1609T>C | non_coding_transcript_exon_variant | 0.2 | linezolid | Uncertain significance |
| rrl | 1475267 | n.1610G>A | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1475275 | n.1618C>T | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1475276 | n.1619T>C | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 0.22 | linezolid | |
| rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 0.22 | linezolid | |
| rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.2 | linezolid | Uncertain significance |
| rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 0.21 | linezolid | |
| rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1475436 | n.1779C>T | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.21 | linezolid | |
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.19 | linezolid | Uncertain significance |
| rrl | 1476031 | n.2374C>T | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| rrl | 1476032 | n.2375C>A | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1476034 | n.2377C>A | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1476048 | n.2391G>A | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1476095 | n.2438C>G | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1476214 | n.2557G>A | non_coding_transcript_exon_variant | 0.23 | linezolid | |
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.23 | linezolid | |
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.25 | linezolid | |
| rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| inhA | 1673338 | c.-864G>A | upstream_gene_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| inhA | 1673985 | c.-217C>G | upstream_gene_variant | 0.14 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674006 | p.Asp189Glu | missense_variant | 0.15 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674015 | c.-187C>T | upstream_gene_variant | 0.12 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| inhA | 1674018 | c.-184G>C | upstream_gene_variant | 0.12 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674021 | c.-181G>C | upstream_gene_variant | 0.12 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674024 | c.-178T>C | upstream_gene_variant | 0.13 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674033 | c.-169T>C | upstream_gene_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674037 | p.Gln200Ala | missense_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674042 | c.-160G>T | upstream_gene_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674049 | p.Gln204Asp | missense_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674054 | c.-148T>C | upstream_gene_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674060 | c.-142A>G | upstream_gene_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674063 | c.-139G>C | upstream_gene_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674079 | p.Pro214Ala | missense_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674534 | c.333G>T | synonymous_variant | 0.64 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674537 | c.336C>G | synonymous_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674542 | p.Ala114Glu | missense_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674549 | c.348G>C | synonymous_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674555 | c.354G>A | synonymous_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674561 | c.360C>T | synonymous_variant | 0.13 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674582 | c.381T>C | synonymous_variant | 0.12 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674585 | c.384T>C | synonymous_variant | 0.12 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674589 | p.Met130Leu | missense_variant | 0.13 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674601 | p.Leu134Thr | missense_variant | 0.12 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674624 | c.423A>C | synonymous_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674703 | c.502T>C | synonymous_variant | 0.13 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674708 | c.507G>A | synonymous_variant | 0.13 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674718 | c.517A>C | synonymous_variant | 0.13 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674738 | c.537C>G | synonymous_variant | 0.13 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674741 | c.540C>T | synonymous_variant | 0.12 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674746 | p.Tyr182Phe | missense_variant | 0.12 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674750 | c.549T>C | synonymous_variant | 0.12 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674753 | c.552G>C | synonymous_variant | 0.12 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674756 | c.555T>C | synonymous_variant | 0.12 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674759 | c.558G>C | synonymous_variant | 0.12 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674774 | c.573A>G | synonymous_variant | 0.13 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674780 | c.579T>G | synonymous_variant | 0.12 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674789 | c.588G>C | synonymous_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674801 | c.600T>C | synonymous_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674816 | c.615T>C | synonymous_variant | 0.1 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674828 | c.627G>A | synonymous_variant | 0.11 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833554 | p.Thr5Ala | missense_variant | 0.13 | pyrazinamide | |
| rpsA | 1833568 | c.27G>C | synonymous_variant | 0.14 | pyrazinamide | |
| rpsA | 1833589 | c.48A>T | synonymous_variant | 0.16 | pyrazinamide | |
| rpsA | 1833595 | c.54T>C | synonymous_variant | 0.16 | pyrazinamide | |
| rpsA | 1833661 | c.120A>G | synonymous_variant | 0.2 | pyrazinamide | |
| rpsA | 1833667 | c.126C>G | synonymous_variant | 0.21 | pyrazinamide | |
| rpsA | 1833721 | c.180A>G | synonymous_variant | 0.19 | pyrazinamide | |
| rpsA | 1833724 | c.183C>G | synonymous_variant | 0.19 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 0.19 | pyrazinamide | |
| rpsA | 1833742 | c.201A>G | synonymous_variant | 0.2 | pyrazinamide | |
| rpsA | 1833745 | c.204G>C | synonymous_variant | 0.2 | pyrazinamide | |
| rpsA | 1833748 | c.207C>G | synonymous_variant | 0.2 | pyrazinamide | |
| rpsA | 1833787 | c.246C>G | synonymous_variant | 0.19 | pyrazinamide | |
| rpsA | 1833790 | c.249T>C | synonymous_variant | 0.19 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 0.19 | pyrazinamide | |
| rpsA | 1833811 | c.270G>T | synonymous_variant | 0.19 | pyrazinamide | |
| rpsA | 1833838 | c.297G>C | synonymous_variant | 0.22 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 0.21 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 0.23 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 0.23 | pyrazinamide | |
| rpsA | 1833874 | c.333T>C | synonymous_variant | 0.21 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 0.22 | pyrazinamide | |
| rpsA | 1833940 | c.399C>G | synonymous_variant | 0.22 | pyrazinamide | |
| rpsA | 1833971 | c.430C>T | synonymous_variant | 0.19 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 0.18 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 0.18 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 0.17 | pyrazinamide | |
| rpsA | 1834030 | c.489C>G | synonymous_variant | 0.16 | pyrazinamide | |
| rpsA | 1834123 | c.582C>G | synonymous_variant | 0.1 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 0.1 | pyrazinamide | |
| rpsA | 1834303 | c.762T>C | synonymous_variant | 0.15 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 0.15 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 0.19 | pyrazinamide | |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 0.19 | pyrazinamide | |
| rpsA | 1834396 | c.855G>C | synonymous_variant | 0.18 | pyrazinamide | |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 0.19 | pyrazinamide | |
| rpsA | 1834417 | c.876G>C | synonymous_variant | 0.2 | pyrazinamide | |
| rpsA | 1834423 | c.882G>C | synonymous_variant | 0.2 | pyrazinamide | |
| rpsA | 1834435 | c.894G>C | synonymous_variant | 0.18 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 0.19 | pyrazinamide | |
| rpsA | 1834465 | c.924T>C | synonymous_variant | 0.17 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 0.16 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 0.16 | pyrazinamide | |
| rpsA | 1834528 | c.987T>C | synonymous_variant | 0.15 | pyrazinamide | |
| rpsA | 1834540 | c.999G>C | synonymous_variant | 0.15 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.15 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.17 | pyrazinamide | |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.17 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.19 | pyrazinamide | |
| rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.16 | pyrazinamide | |
| rpsA | 1834684 | c.1143C>T | synonymous_variant | 0.18 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.18 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.19 | pyrazinamide | |
| rpsA | 1834733 | p.Ala398Ser | missense_variant | 0.19 | pyrazinamide | |
| rpsA | 1834738 | c.1197A>G | synonymous_variant | 0.2 | pyrazinamide | |
| rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.19 | pyrazinamide | |
| rpsA | 1834765 | p.Glu408Asp | missense_variant | 0.18 | pyrazinamide | |
| rpsA | 1834775 | p.Ala412Thr | missense_variant | 0.18 | pyrazinamide | |
| rpsA | 1834780 | c.1239A>G | synonymous_variant | 0.17 | pyrazinamide | |
| rpsA | 1834786 | c.1245A>G | synonymous_variant | 0.16 | pyrazinamide | |
| rpsA | 1834789 | c.1248T>C | synonymous_variant | 0.13 | pyrazinamide | |
| rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.12 | pyrazinamide | |
| tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | |
| ndh | 2101921 | c.1122G>A | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| ndh | 2103112 | c.-70G>T | upstream_gene_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Uncertain significance |
| katG | 2155691 | c.421T>C | synonymous_variant | 0.1 | isoniazid | |
| katG | 2155695 | c.417C>G | synonymous_variant | 0.11 | isoniazid | |
| katG | 2155704 | c.408C>G | synonymous_variant | 0.12 | isoniazid | |
| katG | 2155716 | c.396T>G | synonymous_variant | 0.11 | isoniazid | |
| katG | 2155722 | c.390G>C | synonymous_variant | 0.12 | isoniazid | |
| katG | 2155728 | c.384G>C | synonymous_variant | 0.12 | isoniazid | |
| katG | 2155740 | p.Gly124Gln | missense_variant | 0.13 | isoniazid | |
| katG | 2155743 | c.369G>C | synonymous_variant | 0.13 | isoniazid | |
| katG | 2155746 | c.366C>T | synonymous_variant | 0.13 | isoniazid | |
| PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| PPE35 | 2170065 | p.Ala183Gly | missense_variant | 0.17 | pyrazinamide | |
| Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| pncA | 2290062 | c.-821G>A | upstream_gene_variant | 0.93 | pyrazinamide | |
| pncA | 2290171 | c.-930G>A | upstream_gene_variant | 0.64 | pyrazinamide | |
| kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.17 | isoniazid | |
| kasA | 2518132 | c.18C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518504 | c.390T>C | synonymous_variant | 0.11 | isoniazid | |
| kasA | 2518506 | p.Ala131Glu | missense_variant | 0.11 | isoniazid | |
| kasA | 2518519 | c.405G>C | synonymous_variant | 0.11 | isoniazid | |
| kasA | 2518528 | c.414C>G | synonymous_variant | 0.13 | isoniazid | |
| kasA | 2518540 | c.426T>C | synonymous_variant | 0.15 | isoniazid | |
| kasA | 2518561 | c.447T>C | synonymous_variant | 0.12 | isoniazid | |
| kasA | 2518567 | c.453G>C | synonymous_variant | 0.12 | isoniazid | |
| kasA | 2518570 | c.456G>C | synonymous_variant | 0.12 | isoniazid | |
| kasA | 2518573 | c.459G>C | synonymous_variant | 0.11 | isoniazid | |
| kasA | 2518574 | p.Ile154Val | missense_variant | 0.11 | isoniazid | |
| kasA | 2518579 | c.465T>C | synonymous_variant | 0.11 | isoniazid | |
| kasA | 2518588 | c.474T>C | synonymous_variant | 0.11 | isoniazid | |
| kasA | 2518591 | c.477G>C | synonymous_variant | 0.11 | isoniazid | |
| kasA | 2518732 | c.618C>G | synonymous_variant | 0.1 | isoniazid | |
| kasA | 2518768 | c.654C>T | synonymous_variant | 0.1 | isoniazid | |
| kasA | 2518777 | c.663C>T | synonymous_variant | 0.1 | isoniazid | |
| kasA | 2519095 | c.981C>A | synonymous_variant | 0.11 | isoniazid | |
| kasA | 2519116 | c.1002C>G | synonymous_variant | 0.1 | isoniazid | |
| ahpC | 2726591 | c.399C>G | synonymous_variant | 0.1 | isoniazid | |
| ahpC | 2726593 | p.Val134Ala | missense_variant | 0.1 | isoniazid | |
| ahpC | 2726600 | c.408T>C | synonymous_variant | 0.1 | isoniazid | |
| ahpC | 2726601 | p.Ile137Leu | missense_variant | 0.11 | isoniazid | |
| ahpC | 2726638 | p.Ala149Val | missense_variant | 0.1 | isoniazid | |
| Rv2752c | 3066009 | c.183G>C | synonymous_variant | 0.11 | rifampicin | |
| isoniazid | ||||||
| thyX | 3067355 | c.591A>C | synonymous_variant | 0.1 | para-aminosalicylic_acid | |
| thyX | 3067367 | c.579G>C | synonymous_variant | 0.14 | para-aminosalicylic_acid | |
| thyX | 3067373 | c.573C>G | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
| thyX | 3067391 | c.555G>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
| thyX | 3067394 | c.552G>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
| thyX | 3067439 | c.507A>G | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
| thyX | 3067445 | c.501C>G | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
| thyX | 3067457 | c.489C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
| thyX | 3067465 | p.Ile161Val | missense_variant | 0.17 | para-aminosalicylic_acid | |
| thyX | 3067466 | c.480G>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
| thyX | 3067475 | c.471A>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
| thyX | 3067490 | c.456C>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
| thyX | 3067493 | c.453A>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
| thyX | 3067515 | p.Ser144Thr | missense_variant | 0.2 | para-aminosalicylic_acid | |
| thyX | 3067530 | p.Ala139Ser | missense_variant | 0.22 | para-aminosalicylic_acid | |
| thyX | 3067545 | p.Glu134Ala | missense_variant | 0.23 | para-aminosalicylic_acid | |
| thyX | 3067549 | p.Thr133Ala | missense_variant | 0.22 | para-aminosalicylic_acid | |
| thyX | 3067556 | p.His130Gln | missense_variant | 0.21 | para-aminosalicylic_acid | |
| thyX | 3067559 | c.387C>G | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
| thyX | 3067565 | p.Asp127Glu | missense_variant | 0.22 | para-aminosalicylic_acid | |
| thyX | 3067570 | p.Ala126Pro | missense_variant | 0.23 | para-aminosalicylic_acid | |
| thyX | 3067577 | c.369G>A | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
| thyX | 3067601 | p.Arg115His | missense_variant | 0.19 | para-aminosalicylic_acid | |
| thyX | 3067611 | p.Lys112Thr | missense_variant | 0.2 | para-aminosalicylic_acid | |
| thyX | 3067619 | c.327A>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
| thyX | 3067631 | c.315C>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
| thyX | 3067634 | c.312C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
| thyX | 3067652 | c.294T>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
| thyX | 3067661 | c.285C>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
| thyX | 3067685 | c.261A>C | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
| thyX | 3067691 | p.Ile85Leu | missense_variant | 0.2 | para-aminosalicylic_acid | |
| thyX | 3067694 | c.252G>C | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
| thyX | 3067718 | c.228C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
| thyX | 3067721 | c.225T>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
| thyX | 3067727 | c.219A>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
| thyX | 3067736 | p.Phe70Leu | missense_variant | 0.17 | para-aminosalicylic_acid | |
| thyX | 3067739 | c.207T>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
| thyX | 3067761 | p.Arg62Lys | missense_variant | 0.18 | para-aminosalicylic_acid | |
| thyX | 3067765 | p.Leu61Ile | missense_variant | 0.19 | para-aminosalicylic_acid | |
| thyX | 3067772 | c.174C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
| thyX | 3067781 | c.165C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
| thyX | 3067793 | c.153T>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
| thyX | 3067799 | c.147G>A | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
| thyX | 3067802 | c.144C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
| thyX | 3067814 | c.132T>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
| thyX | 3067850 | c.96A>C | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
| thyX | 3067869 | p.Thr26Ser | missense_variant | 0.13 | para-aminosalicylic_acid | |
| thyX | 3067874 | c.72C>G | synonymous_variant | 0.13 | para-aminosalicylic_acid | |
| thyX | 3067883 | c.63C>G | synonymous_variant | 0.13 | para-aminosalicylic_acid | |
| thyX | 3067886 | c.60A>C | synonymous_variant | 0.13 | para-aminosalicylic_acid | |
| thyX | 3067889 | c.57C>G | synonymous_variant | 0.1 | para-aminosalicylic_acid | |
| thyX | 3067976 | c.-31T>G | upstream_gene_variant | 0.24 | para-aminosalicylic_acid | |
| thyA | 3074106 | c.366T>C | synonymous_variant | 0.1 | para-aminosalicylic_acid | |
| thyA | 3074127 | c.345G>C | synonymous_variant | 0.1 | para-aminosalicylic_acid | |
| ald | 3086987 | p.Gln56His | missense_variant | 0.59 | cycloserine | |
| ald | 3087084 | c.266delA | frameshift_variant | 1.0 | cycloserine | |
| ald | 3087184 | c.368_373delCCGACG | disruptive_inframe_deletion | 1.0 | cycloserine | |
| ald | 3087821 | c.1002G>A | synonymous_variant | 0.14 | cycloserine | |
| ald | 3087825 | p.Asn336Asp | missense_variant | 0.13 | cycloserine | |
| fbiD | 3339734 | p.Ala206Gly | missense_variant | 0.56 | delamanid | |
| fbiD | 3339744 | c.627A>C | synonymous_variant | 0.12 | delamanid | |
| fprA | 3473996 | c.-11_-10insA | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| fprA | 3475159 | p.Asn385Asp | missense_variant | 1.0 | capreomycin | Uncertain significance |
| amikacin | Uncertain significance | |||||
| alr | 3840932 | c.489C>T | synonymous_variant | 1.0 | cycloserine | |
| rpoA | 3877587 | c.921A>G | synonymous_variant | 0.1 | rifampicin | |
| rpoA | 3877613 | p.Ile299Val | missense_variant | 0.15 | rifampicin | |
| rpoA | 3877656 | c.852T>G | synonymous_variant | 0.16 | rifampicin | |
| rpoA | 3877668 | c.840A>G | synonymous_variant | 0.16 | rifampicin | |
| rpoA | 3877679 | p.Ala277Ser | missense_variant | 0.17 | rifampicin | |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 0.16 | rifampicin | |
| rpoA | 3877692 | c.816G>C | synonymous_variant | 0.16 | rifampicin | |
| rpoA | 3877704 | c.804G>C | synonymous_variant | 0.17 | rifampicin | |
| rpoA | 3877737 | c.771G>C | synonymous_variant | 0.2 | rifampicin | |
| rpoA | 3877743 | c.765T>C | synonymous_variant | 0.2 | rifampicin | |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 0.19 | rifampicin | |
| rpoA | 3877770 | c.738A>G | synonymous_variant | 0.19 | rifampicin | |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 0.2 | rifampicin | |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 0.2 | rifampicin | |
| rpoA | 3877791 | c.717C>G | synonymous_variant | 0.19 | rifampicin | |
| rpoA | 3877818 | c.690A>G | synonymous_variant | 0.2 | rifampicin | |
| rpoA | 3877839 | c.669G>C | synonymous_variant | 0.21 | rifampicin | |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 0.22 | rifampicin | |
| rpoA | 3877866 | c.642G>C | synonymous_variant | 0.22 | rifampicin | |
| rpoA | 3877875 | c.633T>G | synonymous_variant | 0.21 | rifampicin | |
| rpoA | 3877878 | c.630G>C | synonymous_variant | 0.21 | rifampicin | |
| rpoA | 3877890 | c.618C>T | synonymous_variant | 0.23 | rifampicin | |
| rpoA | 3877896 | c.612G>C | synonymous_variant | 0.21 | rifampicin | |
| rpoA | 3877900 | p.Ser203Asn | missense_variant | 0.2 | rifampicin | |
| rpoA | 3877905 | c.603A>G | synonymous_variant | 0.19 | rifampicin | |
| rpoA | 3877908 | p.Asn200Ser | missense_variant | 0.2 | rifampicin | |
| rpoA | 3877920 | c.588G>C | synonymous_variant | 0.21 | rifampicin | |
| rpoA | 3877926 | c.582G>C | synonymous_variant | 0.2 | rifampicin | |
| rpoA | 3877962 | c.546G>C | synonymous_variant | 0.21 | rifampicin | |
| rpoA | 3877986 | c.522G>C | synonymous_variant | 0.18 | rifampicin | |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 0.18 | rifampicin | |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 0.2 | rifampicin | |
| rpoA | 3878022 | c.486T>C | synonymous_variant | 0.18 | rifampicin | |
| rpoA | 3878028 | c.480G>C | synonymous_variant | 0.17 | rifampicin | |
| rpoA | 3878031 | c.477T>C | synonymous_variant | 0.16 | rifampicin | |
| rpoA | 3878040 | c.468T>C | synonymous_variant | 0.16 | rifampicin | |
| rpoA | 3878046 | c.462T>C | synonymous_variant | 0.16 | rifampicin | |
| rpoA | 3878055 | c.453A>G | synonymous_variant | 0.14 | rifampicin | |
| rpoA | 3878058 | c.450G>T | synonymous_variant | 0.14 | rifampicin | |
| rpoA | 3878061 | c.447G>C | synonymous_variant | 0.13 | rifampicin | |
| rpoA | 3878067 | c.441C>G | synonymous_variant | 0.13 | rifampicin | |
| rpoA | 3878070 | c.438T>C | synonymous_variant | 0.13 | rifampicin | |
| rpoA | 3878076 | c.432C>T | synonymous_variant | 0.14 | rifampicin | |
| rpoA | 3878094 | c.414C>G | synonymous_variant | 0.14 | rifampicin | |
| rpoA | 3878103 | c.405A>G | synonymous_variant | 0.14 | rifampicin | |
| rpoA | 3878106 | c.402G>C | synonymous_variant | 0.14 | rifampicin | |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 0.15 | rifampicin | |
| rpoA | 3878130 | c.378C>G | synonymous_variant | 0.15 | rifampicin | |
| rpoA | 3878141 | p.Met123Leu | missense_variant | 0.15 | rifampicin | |
| rpoA | 3878143 | p.Gly122Asp | missense_variant | 0.15 | rifampicin | Uncertain significance |
| rpoA | 3878157 | c.351C>G | synonymous_variant | 0.16 | rifampicin | |
| rpoA | 3878163 | c.345C>T | synonymous_variant | 0.16 | rifampicin | |
| rpoA | 3878169 | c.339G>A | synonymous_variant | 0.16 | rifampicin | |
| rpoA | 3878172 | c.336G>C | synonymous_variant | 0.16 | rifampicin | |
| rpoA | 3878175 | c.333G>C | synonymous_variant | 0.17 | rifampicin | |
| rpoA | 3878187 | c.321C>G | synonymous_variant | 0.17 | rifampicin | |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 0.16 | rifampicin | |
| rpoA | 3878199 | c.309T>C | synonymous_variant | 0.18 | rifampicin | |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 0.18 | rifampicin | |
| rpoA | 3878226 | c.282C>G | synonymous_variant | 0.19 | rifampicin | |
| rpoA | 3878232 | c.276G>C | synonymous_variant | 0.19 | rifampicin | |
| rpoA | 3878247 | c.261G>C | synonymous_variant | 0.19 | rifampicin | |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 0.21 | rifampicin | |
| rpoA | 3878284 | p.Glu75Ala | missense_variant | 0.2 | rifampicin | |
| rpoA | 3878292 | c.216T>C | synonymous_variant | 0.2 | rifampicin | |
| rpoA | 3878298 | c.210A>G | synonymous_variant | 0.18 | rifampicin | |
| rpoA | 3878304 | c.204G>C | synonymous_variant | 0.18 | rifampicin | |
| rpoA | 3878310 | c.198G>C | synonymous_variant | 0.19 | rifampicin | |
| rpoA | 3878313 | c.195G>C | synonymous_variant | 0.2 | rifampicin | |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 0.21 | rifampicin | |
| rpoA | 3878331 | c.177A>G | synonymous_variant | 0.19 | rifampicin | |
| rpoA | 3878334 | c.174T>C | synonymous_variant | 0.19 | rifampicin | |
| rpoA | 3878337 | c.171T>C | synonymous_variant | 0.2 | rifampicin | |
| rpoA | 3878346 | c.162T>C | synonymous_variant | 0.22 | rifampicin | |
| rpoA | 3878364 | c.144A>C | synonymous_variant | 0.22 | rifampicin | |
| rpoA | 3878367 | c.141C>G | synonymous_variant | 0.22 | rifampicin | |
| rpoA | 3878376 | c.132G>C | synonymous_variant | 0.23 | rifampicin | |
| rpoA | 3878385 | c.123C>G | synonymous_variant | 0.2 | rifampicin | |
| rpoA | 3878388 | c.120C>G | synonymous_variant | 0.2 | rifampicin | |
| rpoA | 3878391 | c.117T>C | synonymous_variant | 0.21 | rifampicin | |
| rpoA | 3878415 | c.93C>T | synonymous_variant | 0.19 | rifampicin | |
| rpoA | 3878424 | c.84G>C | synonymous_variant | 0.17 | rifampicin | |
| rpoA | 3878436 | c.72A>G | synonymous_variant | 0.17 | rifampicin | |
| rpoA | 3878442 | c.66G>C | synonymous_variant | 0.16 | rifampicin | |
| rpoA | 3878454 | c.54A>C | synonymous_variant | 0.17 | rifampicin | |
| rpoA | 3878463 | c.45C>A | synonymous_variant | 0.14 | rifampicin | |
| rpoA | 3878472 | p.Asp12Glu | missense_variant | 0.13 | rifampicin | |
| rpoA | 3878478 | c.30C>G | synonymous_variant | 0.13 | rifampicin | |
| rpoA | 3878484 | c.24C>A | synonymous_variant | 0.13 | rifampicin | |
| rpoA | 3878490 | c.18C>A | synonymous_variant | 0.11 | rifampicin | |
| rpoA | 3878496 | c.12A>T | synonymous_variant | 0.11 | rifampicin | |
| ddn | 3986987 | c.144G>T | synonymous_variant | 1.0 | delamanid | |
| ddn | 3987180 | p.Asp113Asn | missense_variant | 1.0 | delamanid | |
| clpC1 | 4038212 | c.2493T>C | synonymous_variant | 0.1 | pyrazinamide | |
| clpC1 | 4038239 | c.2466T>C | synonymous_variant | 0.1 | pyrazinamide | |
| clpC1 | 4038255 | p.Val817Lys | missense_variant | 0.1 | pyrazinamide | |
| clpC1 | 4038293 | c.2412G>C | synonymous_variant | 0.11 | pyrazinamide | |
| clpC1 | 4038302 | c.2403C>G | synonymous_variant | 0.11 | pyrazinamide | |
| clpC1 | 4038308 | c.2397G>T | synonymous_variant | 0.11 | pyrazinamide | |
| clpC1 | 4038314 | c.2391T>C | synonymous_variant | 0.1 | pyrazinamide | |
| clpC1 | 4038317 | c.2388G>C | synonymous_variant | 0.11 | pyrazinamide | |
| clpC1 | 4038320 | c.2385G>T | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4038356 | c.2349T>C | synonymous_variant | 0.11 | pyrazinamide | |
| clpC1 | 4038359 | c.2346A>G | synonymous_variant | 0.11 | pyrazinamide | |
| clpC1 | 4038419 | c.2286T>C | synonymous_variant | 0.13 | pyrazinamide | |
| clpC1 | 4038433 | c.2272C>T | synonymous_variant | 0.14 | pyrazinamide | |
| clpC1 | 4038434 | c.2271G>A | synonymous_variant | 0.13 | pyrazinamide | |
| clpC1 | 4038444 | p.Ala754Lys | missense_variant | 0.14 | pyrazinamide | |
| clpC1 | 4038446 | c.2259T>C | synonymous_variant | 0.14 | pyrazinamide | |
| clpC1 | 4038456 | p.Val750Glu | missense_variant | 0.15 | pyrazinamide | |
| clpC1 | 4038460 | p.Leu749Met | missense_variant | 0.16 | pyrazinamide | |
| clpC1 | 4038486 | p.Gly740Asn | missense_variant | 0.14 | pyrazinamide | |
| clpC1 | 4038489 | p.Ala739Gly | missense_variant | 0.15 | pyrazinamide | |
| clpC1 | 4038494 | c.2211G>C | synonymous_variant | 0.15 | pyrazinamide | |
| clpC1 | 4038497 | p.Ser736Gln | missense_variant | 0.15 | pyrazinamide | |
| clpC1 | 4038509 | c.2196C>T | synonymous_variant | 0.17 | pyrazinamide | |
| clpC1 | 4038530 | p.Glu725Asp | missense_variant | 0.18 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4038640 | p.Asp689Asn | missense_variant | 0.1 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>C | synonymous_variant | 0.13 | pyrazinamide | |
| clpC1 | 4038683 | c.2022T>C | synonymous_variant | 0.16 | pyrazinamide | |
| clpC1 | 4038695 | c.2010C>G | synonymous_variant | 0.18 | pyrazinamide | |
| clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.18 | pyrazinamide | |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.18 | pyrazinamide | |
| clpC1 | 4038707 | c.1998C>G | synonymous_variant | 0.18 | pyrazinamide | |
| clpC1 | 4038710 | c.1995G>C | synonymous_variant | 0.18 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.18 | pyrazinamide | |
| clpC1 | 4038749 | c.1956C>A | synonymous_variant | 0.21 | pyrazinamide | |
| clpC1 | 4038755 | c.1950G>T | synonymous_variant | 0.21 | pyrazinamide | |
| clpC1 | 4038770 | c.1935C>T | synonymous_variant | 0.21 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.22 | pyrazinamide | |
| clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.22 | pyrazinamide | |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.21 | pyrazinamide | |
| clpC1 | 4038845 | c.1860G>C | synonymous_variant | 0.23 | pyrazinamide | |
| clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.24 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.25 | pyrazinamide | |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.27 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.26 | pyrazinamide | |
| clpC1 | 4038923 | c.1780_1782delCTAinsTTG | synonymous_variant | 0.25 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.26 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.27 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.3 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.28 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.29 | pyrazinamide | |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.3 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.27 | pyrazinamide | |
| clpC1 | 4039004 | c.1701C>G | synonymous_variant | 0.27 | pyrazinamide | |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.24 | pyrazinamide | |
| clpC1 | 4039064 | c.1641C>T | synonymous_variant | 0.23 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.22 | pyrazinamide | |
| clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.21 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.21 | pyrazinamide | |
| clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.21 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.21 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.21 | pyrazinamide | |
| clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.19 | pyrazinamide | |
| clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.19 | pyrazinamide | |
| clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.19 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 0.18 | pyrazinamide | |
| clpC1 | 4039186 | c.1519C>T | synonymous_variant | 0.18 | pyrazinamide | |
| clpC1 | 4039190 | c.1515C>G | synonymous_variant | 0.17 | pyrazinamide | |
| clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.14 | pyrazinamide | |
| clpC1 | 4039229 | c.1476C>G | synonymous_variant | 0.16 | pyrazinamide | |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.16 | pyrazinamide | |
| clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.15 | pyrazinamide | |
| clpC1 | 4039295 | c.1410A>C | synonymous_variant | 0.15 | pyrazinamide | |
| clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.14 | pyrazinamide | |
| clpC1 | 4039319 | c.1386T>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039322 | c.1383T>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039328 | c.1377A>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039331 | c.1374C>G | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039337 | p.Thr456Gln | missense_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039349 | c.1356C>T | synonymous_variant | 0.13 | pyrazinamide | |
| clpC1 | 4039352 | c.1353C>G | synonymous_variant | 0.13 | pyrazinamide | |
| clpC1 | 4039364 | c.1341C>G | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039391 | c.1314T>G | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039409 | c.1296T>C | synonymous_variant | 0.1 | pyrazinamide | |
| clpC1 | 4039556 | c.1149G>C | synonymous_variant | 0.11 | pyrazinamide | |
| clpC1 | 4039559 | c.1146C>G | synonymous_variant | 0.11 | pyrazinamide | |
| clpC1 | 4039562 | c.1143C>G | synonymous_variant | 0.11 | pyrazinamide | |
| clpC1 | 4039565 | c.1140G>C | synonymous_variant | 0.1 | pyrazinamide | |
| clpC1 | 4039570 | p.Met379Leu | missense_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039576 | p.Ala377Pro | missense_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039589 | c.1116G>C | synonymous_variant | 0.14 | pyrazinamide | |
| clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039661 | c.1044T>G | synonymous_variant | 0.14 | pyrazinamide | |
| clpC1 | 4039664 | c.1041G>C | synonymous_variant | 0.13 | pyrazinamide | |
| clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.13 | pyrazinamide | |
| clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.14 | pyrazinamide | |
| clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039757 | c.948A>G | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039760 | c.945T>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039775 | c.930G>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039781 | c.924G>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039790 | c.915C>G | synonymous_variant | 0.13 | pyrazinamide | |
| clpC1 | 4039817 | c.888A>C | synonymous_variant | 0.11 | pyrazinamide | |
| clpC1 | 4039820 | c.885T>G | synonymous_variant | 0.11 | pyrazinamide | |
| clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039928 | c.775_777delAGCinsTCG | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039937 | c.768G>C | synonymous_variant | 0.14 | pyrazinamide | |
| clpC1 | 4039946 | c.759A>C | synonymous_variant | 0.14 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.13 | pyrazinamide | |
| clpC1 | 4039982 | c.723G>A | synonymous_variant | 0.13 | pyrazinamide | |
| clpC1 | 4039988 | c.717C>G | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.13 | pyrazinamide | |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.13 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4040036 | c.669C>G | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 0.11 | pyrazinamide | |
| clpC1 | 4040093 | c.612C>G | synonymous_variant | 0.1 | pyrazinamide | |
| clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.13 | pyrazinamide | |
| clpC1 | 4040162 | c.543G>C | synonymous_variant | 0.13 | pyrazinamide | |
| clpC1 | 4040165 | c.540G>C | synonymous_variant | 0.14 | pyrazinamide | |
| clpC1 | 4040171 | c.534C>G | synonymous_variant | 0.13 | pyrazinamide | |
| clpC1 | 4040201 | c.504C>G | synonymous_variant | 0.1 | pyrazinamide | |
| clpC1 | 4040225 | c.480A>C | synonymous_variant | 0.1 | pyrazinamide | |
| clpC1 | 4040237 | c.468C>T | synonymous_variant | 0.14 | pyrazinamide | |
| clpC1 | 4040246 | c.459C>G | synonymous_variant | 0.16 | pyrazinamide | |
| clpC1 | 4040249 | c.456A>G | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4040267 | c.438A>G | synonymous_variant | 0.19 | pyrazinamide | |
| clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.17 | pyrazinamide | |
| clpC1 | 4040276 | c.427_429delTCCinsAGT | synonymous_variant | 0.16 | pyrazinamide | |
| clpC1 | 4040279 | c.426C>G | synonymous_variant | 0.16 | pyrazinamide | |
| clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.17 | pyrazinamide | |
| clpC1 | 4040318 | c.387C>G | synonymous_variant | 0.17 | pyrazinamide | |
| clpC1 | 4040330 | c.375C>G | synonymous_variant | 0.14 | pyrazinamide | |
| clpC1 | 4040342 | c.363C>G | synonymous_variant | 0.13 | pyrazinamide | |
| clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.13 | pyrazinamide | |
| clpC1 | 4040363 | c.342A>T | synonymous_variant | 0.12 | pyrazinamide | |
| clpC1 | 4040369 | c.336C>G | synonymous_variant | 0.11 | pyrazinamide | |
| clpC1 | 4040824 | c.-120C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
| embC | 4239843 | c.-20A>C | upstream_gene_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4240671 | p.Thr270Ile | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4240699 | c.837C>G | synonymous_variant | 0.11 | ethambutol | |
| embC | 4240726 | c.864G>C | synonymous_variant | 0.15 | ethambutol | |
| embC | 4240780 | c.918T>C | synonymous_variant | 0.18 | ethambutol | |
| embC | 4240783 | c.921G>C | synonymous_variant | 0.18 | ethambutol | |
| embC | 4240789 | c.927T>C | synonymous_variant | 0.18 | ethambutol | |
| embC | 4240819 | c.957A>G | synonymous_variant | 0.18 | ethambutol | |
| embC | 4240828 | c.966G>A | synonymous_variant | 0.17 | ethambutol | |
| embC | 4240831 | c.969T>G | synonymous_variant | 0.16 | ethambutol | |
| embC | 4241047 | c.1185C>G | synonymous_variant | 0.11 | ethambutol | |
| embC | 4241050 | c.1188T>G | synonymous_variant | 0.11 | ethambutol | |
| embC | 4241053 | c.1191G>C | synonymous_variant | 0.11 | ethambutol | |
| embC | 4241089 | c.1227C>G | synonymous_variant | 0.12 | ethambutol | |
| embC | 4241095 | c.1233C>T | synonymous_variant | 0.13 | ethambutol | |
| embC | 4241107 | c.1245G>C | synonymous_variant | 0.14 | ethambutol | |
| embC | 4241140 | c.1278A>G | synonymous_variant | 0.14 | ethambutol | |
| embC | 4241146 | c.1284C>G | synonymous_variant | 0.15 | ethambutol | |
| embC | 4241158 | c.1296T>C | synonymous_variant | 0.12 | ethambutol | |
| embC | 4241161 | c.1299C>G | synonymous_variant | 0.11 | ethambutol | |
| embC | 4241162 | c.1300T>C | synonymous_variant | 0.11 | ethambutol | |
| embC | 4241170 | c.1308G>C | synonymous_variant | 0.11 | ethambutol | |
| embC | 4241173 | c.1311C>T | synonymous_variant | 0.11 | ethambutol | |
| embC | 4241479 | c.1617C>G | synonymous_variant | 0.1 | ethambutol | |
| embC | 4241480 | c.1618T>C | synonymous_variant | 0.1 | ethambutol | |
| embC | 4241488 | c.1626G>C | synonymous_variant | 0.11 | ethambutol | |
| embC | 4241496 | p.Ala545Gly | missense_variant | 0.11 | ethambutol | |
| embC | 4241500 | c.1638A>C | synonymous_variant | 0.1 | ethambutol | |
| embC | 4241501 | p.Ser547Thr | missense_variant | 0.11 | ethambutol | |
| embC | 4241506 | c.1644G>C | synonymous_variant | 0.12 | ethambutol | |
| embC | 4241518 | c.1656A>G | synonymous_variant | 0.14 | ethambutol | |
| embC | 4241521 | c.1659T>C | synonymous_variant | 0.13 | ethambutol | |
| embC | 4241530 | c.1668C>A | synonymous_variant | 0.15 | ethambutol | |
| embC | 4241536 | c.1674A>G | synonymous_variant | 0.14 | ethambutol | |
| embC | 4241539 | c.1677T>C | synonymous_variant | 0.14 | ethambutol | |
| embC | 4241545 | c.1683T>C | synonymous_variant | 0.15 | ethambutol | |
| embC | 4241551 | c.1689A>G | synonymous_variant | 0.14 | ethambutol | |
| embC | 4241567 | p.Ile569Val | missense_variant | 0.14 | ethambutol | Uncertain significance |
| embC | 4241572 | c.1710C>G | synonymous_variant | 0.13 | ethambutol | |
| embC | 4241578 | c.1716G>C | synonymous_variant | 0.13 | ethambutol | |
| embC | 4241584 | c.1722T>C | synonymous_variant | 0.14 | ethambutol | |
| embC | 4241587 | c.1725C>G | synonymous_variant | 0.12 | ethambutol | |
| embC | 4241591 | p.Leu577Val | missense_variant | 0.12 | ethambutol | |
| embC | 4241611 | c.1749G>C | synonymous_variant | 0.1 | ethambutol | |
| embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242823 | c.-410G>C | upstream_gene_variant | 0.11 | ethambutol | |
| embA | 4242832 | c.-401A>C | upstream_gene_variant | 0.11 | ethambutol | |
| embA | 4242838 | c.-395C>G | upstream_gene_variant | 0.11 | ethambutol | |
| embA | 4242841 | c.-392C>T | upstream_gene_variant | 0.1 | ethambutol | |
| embA | 4242844 | c.-389A>G | upstream_gene_variant | 0.1 | ethambutol | |
| embA | 4242847 | c.-386C>A | upstream_gene_variant | 0.1 | ethambutol | |
| embA | 4244220 | c.988C>T | synonymous_variant | 0.99 | ethambutol | |
| embA | 4244635 | p.Val468Ala | missense_variant | 0.97 | ethambutol | Uncertain significance |
| embA | 4245083 | c.1851A>C | synonymous_variant | 0.11 | ethambutol | |
| embA | 4245086 | c.1854C>G | synonymous_variant | 0.11 | ethambutol | |
| embA | 4245089 | c.1857G>C | synonymous_variant | 0.11 | ethambutol | |
| embA | 4245098 | c.1866C>T | synonymous_variant | 0.13 | ethambutol | |
| embA | 4245101 | c.1869G>C | synonymous_variant | 0.14 | ethambutol | |
| embA | 4245137 | c.1905T>C | synonymous_variant | 0.18 | ethambutol | |
| embA | 4245146 | c.1914G>A | synonymous_variant | 0.18 | ethambutol | |
| embA | 4245147 | p.Pro639Ser | missense_variant | 0.82 | ethambutol | Uncertain significance |
| embA | 4245153 | p.Ile641Val | missense_variant | 0.17 | ethambutol | |
| embA | 4245182 | c.1950T>C | synonymous_variant | 0.19 | ethambutol | |
| embA | 4245189 | c.1957C>T | synonymous_variant | 0.19 | ethambutol | |
| embA | 4245198 | p.Leu656Ile | missense_variant | 0.18 | ethambutol | |
| embA | 4245207 | c.1975T>C | synonymous_variant | 0.18 | ethambutol | |
| embA | 4245215 | c.1983A>C | synonymous_variant | 0.16 | ethambutol | |
| embA | 4245222 | p.Tyr664Gln | missense_variant | 0.16 | ethambutol | |
| embA | 4245248 | c.2016G>C | synonymous_variant | 0.15 | ethambutol | |
| embA | 4245257 | c.2025A>G | synonymous_variant | 0.14 | ethambutol | |
| embA | 4245263 | c.2031A>G | synonymous_variant | 0.13 | ethambutol | |
| embB | 4246584 | p.Arg24Pro | missense_variant | 0.15 | ethambutol | |
| embB | 4247407 | c.894G>C | synonymous_variant | 0.1 | ethambutol | |
| embB | 4247425 | c.912G>C | synonymous_variant | 0.11 | ethambutol | |
| embB | 4247434 | c.921C>G | synonymous_variant | 0.12 | ethambutol | |
| embB | 4247437 | c.924A>G | synonymous_variant | 0.12 | ethambutol | |
| embB | 4247440 | c.927C>G | synonymous_variant | 0.13 | ethambutol | |
| embB | 4247446 | c.933C>T | synonymous_variant | 0.12 | ethambutol | |
| embB | 4247464 | c.951C>G | synonymous_variant | 0.14 | ethambutol | |
| embB | 4247470 | c.957T>C | synonymous_variant | 0.14 | ethambutol | |
| embB | 4247491 | c.978G>C | synonymous_variant | 0.18 | ethambutol | |
| embB | 4247497 | c.984T>C | synonymous_variant | 0.19 | ethambutol | |
| embB | 4247512 | c.999T>C | synonymous_variant | 0.18 | ethambutol | |
| embB | 4247539 | c.1026T>C | synonymous_variant | 0.16 | ethambutol | |
| embB | 4247554 | c.1041T>C | synonymous_variant | 0.15 | ethambutol | |
| embB | 4247566 | c.1053C>A | synonymous_variant | 0.15 | ethambutol | |
| embB | 4247572 | c.1059A>G | synonymous_variant | 0.14 | ethambutol | |
| embB | 4247579 | p.Ala356Phe | missense_variant | 0.13 | ethambutol | |
| embB | 4247587 | c.1074G>A | synonymous_variant | 0.12 | ethambutol | |
| embB | 4247603 | c.1090C>T | synonymous_variant | 0.13 | ethambutol | |
| embB | 4247611 | c.1098G>T | synonymous_variant | 0.12 | ethambutol | |
| embB | 4247614 | c.1101T>C | synonymous_variant | 0.12 | ethambutol | |
| embB | 4247646 | p.Glu378Ala | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4247761 | c.1248T>C | synonymous_variant | 0.11 | ethambutol | |
| embB | 4247773 | c.1260G>A | synonymous_variant | 0.1 | ethambutol | |
| embB | 4247776 | c.1263G>T | synonymous_variant | 0.1 | ethambutol | |
| embB | 4247797 | c.1284C>G | synonymous_variant | 0.12 | ethambutol | |
| embB | 4247800 | c.1287A>T | synonymous_variant | 0.12 | ethambutol | |
| embB | 4247803 | c.1290G>C | synonymous_variant | 0.12 | ethambutol | |
| embB | 4247815 | c.1302C>G | synonymous_variant | 0.12 | ethambutol | |
| embB | 4247819 | p.Val436Ile | missense_variant | 0.12 | ethambutol | |
| embB | 4247830 | c.1317A>C | synonymous_variant | 0.11 | ethambutol | |
| embB | 4247836 | c.1323A>G | synonymous_variant | 0.1 | ethambutol | |
| embB | 4247839 | c.1326G>C | synonymous_variant | 0.1 | ethambutol | |
| embB | 4247866 | c.1353G>C | synonymous_variant | 0.15 | ethambutol | |
| embB | 4247875 | c.1362G>C | synonymous_variant | 0.14 | ethambutol | |
| embB | 4247876 | c.1363C>T | synonymous_variant | 0.15 | ethambutol | |
| embB | 4247881 | c.1368G>C | synonymous_variant | 0.15 | ethambutol | |
| embB | 4247887 | c.1374C>T | synonymous_variant | 0.15 | ethambutol | |
| embB | 4247899 | p.Met462Ile | missense_variant | 0.16 | ethambutol | |
| embB | 4247905 | c.1392G>C | synonymous_variant | 0.14 | ethambutol | |
| embB | 4247909 | c.1396T>C | synonymous_variant | 0.14 | ethambutol | |
| embB | 4247914 | c.1401G>C | synonymous_variant | 0.14 | ethambutol | |
| embB | 4247932 | c.1419C>G | synonymous_variant | 0.14 | ethambutol | |
| embB | 4247940 | p.Leu476Trp | missense_variant | 0.13 | ethambutol | |
| embB | 4247945 | c.1432T>C | synonymous_variant | 0.14 | ethambutol | |
| embB | 4247951 | p.Ser480Ala | missense_variant | 0.14 | ethambutol | |
| embB | 4247956 | c.1443G>C | synonymous_variant | 0.14 | ethambutol | |
| embB | 4247974 | c.1461C>G | synonymous_variant | 0.12 | ethambutol | |
| embB | 4248007 | c.1494C>G | synonymous_variant | 0.12 | ethambutol | |
| embB | 4248011 | p.Ser500Arg | missense_variant | 0.12 | ethambutol | |
| embB | 4248014 | p.Thr501Ala | missense_variant | 0.12 | ethambutol | |
| embB | 4248035 | p.Val508Ile | missense_variant | 0.13 | ethambutol | |
| embB | 4248040 | c.1527C>G | synonymous_variant | 0.13 | ethambutol | |
| embB | 4248041 | p.Ala510Thr | missense_variant | 0.12 | ethambutol | Uncertain significance |
| embB | 4248044 | p.Lys511Ala | missense_variant | 0.12 | ethambutol | |
| embB | 4248070 | c.1557T>C | synonymous_variant | 0.13 | ethambutol | |
| embB | 4248073 | c.1560C>A | synonymous_variant | 0.65 | ethambutol | |
| embB | 4248085 | c.1572T>C | synonymous_variant | 0.13 | ethambutol | |
| embB | 4248097 | c.1584C>G | synonymous_variant | 0.12 | ethambutol | |
| embB | 4248130 | c.1617G>C | synonymous_variant | 0.11 | ethambutol | |
| embB | 4248133 | c.1620C>G | synonymous_variant | 0.11 | ethambutol | |
| embB | 4248139 | c.1626C>G | synonymous_variant | 0.11 | ethambutol | |
| embB | 4248142 | c.1629T>C | synonymous_variant | 0.11 | ethambutol | |
| embB | 4248143 | c.1630T>C | synonymous_variant | 0.11 | ethambutol | |
| embB | 4248157 | c.1644A>G | synonymous_variant | 0.11 | ethambutol | |
| embB | 4248172 | c.1659G>C | synonymous_variant | 0.12 | ethambutol | |
| embB | 4248199 | c.1686A>G | synonymous_variant | 0.11 | ethambutol | |
| embB | 4248200 | p.Ile563Val | missense_variant | 0.11 | ethambutol | |
| embB | 4248205 | c.1692C>G | synonymous_variant | 0.11 | ethambutol | |
| embB | 4248206 | p.Ser565Gly | missense_variant | 0.11 | ethambutol | Uncertain significance |
| embB | 4248220 | c.1707A>C | synonymous_variant | 0.13 | ethambutol | |
| embB | 4248304 | c.1791G>C | synonymous_variant | 0.13 | ethambutol | |
| embB | 4248319 | c.1806A>G | synonymous_variant | 0.15 | ethambutol | |
| embB | 4248343 | c.1830G>C | synonymous_variant | 0.11 | ethambutol | |
| embB | 4248350 | c.1837T>C | synonymous_variant | 0.1 | ethambutol | |
| embB | 4248355 | c.1842A>C | synonymous_variant | 0.1 | ethambutol | |
| embB | 4248361 | c.1848A>G | synonymous_variant | 0.1 | ethambutol | |
| embB | 4249369 | c.2856T>C | synonymous_variant | 0.11 | ethambutol | |
| embB | 4249375 | c.2862G>C | synonymous_variant | 0.13 | ethambutol | |
| embB | 4249381 | c.2868A>G | synonymous_variant | 0.14 | ethambutol | |
| embB | 4249417 | c.2904A>G | synonymous_variant | 0.12 | ethambutol | |
| embB | 4249423 | p.Asp970Glu | missense_variant | 0.11 | ethambutol | Uncertain significance |
| embB | 4249424 | p.Leu971Met | missense_variant | 0.11 | ethambutol | |
| embB | 4249429 | c.2916C>T | synonymous_variant | 0.11 | ethambutol | |
| embB | 4249432 | c.2919A>G | synonymous_variant | 0.11 | ethambutol | |
| embB | 4249435 | c.2922G>A | synonymous_variant | 0.1 | ethambutol | |
| embB | 4249441 | c.2928A>G | synonymous_variant | 0.11 | ethambutol | |
| embB | 4249444 | c.2931T>C | synonymous_variant | 0.11 | ethambutol | |
| embB | 4249447 | c.2934G>C | synonymous_variant | 0.12 | ethambutol | |
| embB | 4249469 | p.Leu986Met | missense_variant | 0.16 | ethambutol | |
| embB | 4249486 | c.2973T>G | synonymous_variant | 0.16 | ethambutol | |
| embB | 4249498 | c.2985G>C | synonymous_variant | 0.15 | ethambutol | |
| embB | 4249521 | p.Ala1003Val | missense_variant | 0.14 | ethambutol | |
| embB | 4249525 | c.3012T>C | synonymous_variant | 0.13 | ethambutol | |
| embB | 4249529 | p.Ile1006Val | missense_variant | 0.13 | ethambutol | |
| embB | 4249532 | p.Ala1007Thr | missense_variant | 0.13 | ethambutol | Uncertain significance |
| embB | 4249537 | c.3024A>G | synonymous_variant | 0.13 | ethambutol | |
| embB | 4249543 | c.3030G>C | synonymous_variant | 0.14 | ethambutol | |
| embB | 4249546 | c.3033G>A | synonymous_variant | 0.13 | ethambutol | |
| embB | 4249558 | c.3045A>C | synonymous_variant | 0.12 | ethambutol | |
| embB | 4249568 | p.Ser1019Thr | missense_variant | 0.11 | ethambutol | |
| embB | 4249573 | c.3060T>C | synonymous_variant | 0.11 | ethambutol | |
| embB | 4249580 | p.Leu1023Met | missense_variant | 0.12 | ethambutol | |
| embB | 4249594 | c.3081G>C | synonymous_variant | 0.13 | ethambutol | |
| embB | 4249606 | c.3093C>A | synonymous_variant | 0.13 | ethambutol | |
| embB | 4249609 | c.3096T>C | synonymous_variant | 0.12 | ethambutol | |
| embB | 4249615 | c.3102C>G | synonymous_variant | 0.11 | ethambutol | |
| embB | 4249618 | c.3105C>G | synonymous_variant | 0.1 | ethambutol | |
| embB | 4249624 | c.3111C>G | synonymous_variant | 0.1 | ethambutol | |
| embB | 4249627 | c.3114G>C | synonymous_variant | 0.1 | ethambutol | |
| ubiA | 4269387 | p.Glu149Asp | missense_variant | 1.0 | ethambutol | Uncertain significance |
| aftB | 4269606 | c.-770T>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| ethR | 4326928 | c.-621G>A | upstream_gene_variant | 0.23 | ethionamide | |
| ethA | 4327103 | p.Gly124Asp | missense_variant | 1.0 | ethionamide | Uncertain significance |
| whiB6 | 4338546 | c.-25G>A | upstream_gene_variant | 0.32 | streptomycin | Uncertain significance |
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | streptomycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| gid | 4407588 | c.615A>G | synonymous_variant | 1.0 | streptomycin | |
| gid | 4407960 | p.Ile81Arg | missense_variant | 0.67 | streptomycin | Uncertain significance |
