TB-Profiler result

Run: ERR4769493
Summary

Run ID: ERR4769493

Sample name:

Date: 2024-10-05T07:13:34.716034

Number of reads: 223905

Percentage reads mapped: 5.59

Median coverage: 1.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.99
lineage4.9 Euro-American (H37Rv-like) None 0.92
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin rrs n.799C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin gyrB p.Ile486Leu Uncertain significance Mutation from literature
p.Thr500Asn Uncertain significance Mutation from literature
ofloxacin
levofloxacin gyrB p.Ile486Leu Uncertain significance Mutation from literature
p.Thr500Asn Uncertain significance Mutation from literature
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
gyrB 6695 p.Ile486Leu missense_variant 0.93 levofloxacin Uncertain significance Mutation from literature
moxifloxacin Uncertain significance Mutation from literature
gyrB 6738 p.Thr500Asn missense_variant 0.91 levofloxacin Uncertain significance Mutation from literature
moxifloxacin Uncertain significance Mutation from literature
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrA 6673 c.-629A>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6685 c.-617C>A upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrB 6710 p.Ala491Ser missense_variant 0.93 levofloxacin
moxifloxacin
gyrB 6716 p.Ile493Leu missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 6724 c.-578G>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrB 6725 p.Val496Thr missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 0.92 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrB 6808 c.1569C>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6826 c.-476G>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
hadA 731568 c.-361_*1115del transcript_ablation 0.94 isoniazid Uncertain significance
rpoB 761150 c.1344A>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761174 c.1368T>C synonymous_variant 0.98 rifampicin
rpoB 761180 c.1374A>T synonymous_variant 0.98 rifampicin
rpoB 761183 c.1377T>C synonymous_variant 0.98 rifampicin
rpoB 761189 c.1383T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761213 c.1407G>C synonymous_variant 0.99 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761252 c.1446C>G synonymous_variant 1.0 rifampicin
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761294 c.1488G>C synonymous_variant 1.0 rifampicin
rpoB 761300 c.1494G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761303 c.1497G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 1.0 rifampicin
rpoB 761315 c.1509C>T synonymous_variant 0.89 rifampicin
rpoB 761318 c.1512G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.85 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761951 c.2145G>C synonymous_variant 0.93 rifampicin
rpoB 761955 p.Ile717Phe missense_variant 0.93 rifampicin
rpoB 761998 c.2193_2195delGTC disruptive_inframe_deletion 0.97 rifampicin
rpoB 762005 c.2200_2201insAGC disruptive_inframe_insertion 0.97 rifampicin
rpoB 762009 p.Leu735Met missense_variant 0.97 rifampicin
rpoB 762014 c.2208C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762020 p.Glu738Asp missense_variant 0.97 rifampicin
rpoB 762024 p.Val740Ile missense_variant 0.97 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762084 p.Ala760Pro missense_variant 1.0 rifampicin
rpoB 762101 c.2295C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762104 p.Asp766Glu missense_variant 0.93 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762197 c.2391C>G synonymous_variant 0.91 rifampicin
rpoB 762209 c.2403C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 0.94 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762266 c.2460T>C synonymous_variant 0.94 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762296 c.2490G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762297 p.Leu831Met missense_variant 0.91 rifampicin
rpoB 762300 p.Lys832Arg missense_variant 0.91 rifampicin
rpoB 762308 c.2502G>C synonymous_variant 0.91 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoB 762441 p.Leu879Met missense_variant 1.0 rifampicin
rpoB 762452 c.2646G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762455 c.-915C>T upstream_gene_variant 0.93 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 1.0 rifampicin
rpoC 762503 c.-867G>C upstream_gene_variant 1.0 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 1.0 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 1.0 rifampicin Uncertain significance
rpoC 762527 c.-843G>C upstream_gene_variant 1.0 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoB 762534 p.Ile910Leu missense_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762560 c.-810A>C upstream_gene_variant 1.0 rifampicin
rpoC 762563 c.-807G>A upstream_gene_variant 1.0 rifampicin
rpoB 762836 c.3030C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762850 p.Tyr1015Phe missense_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762858 p.Thr1018Ser missense_variant 1.0 rifampicin
rpoC 762863 c.-507T>G upstream_gene_variant 1.0 rifampicin
rpoB 762878 p.Ile1024Met missense_variant 0.97 rifampicin
rpoB 762879 p.Met1025Leu missense_variant 0.97 rifampicin Uncertain significance
rpoB 762905 p.Asp1033Glu missense_variant 0.98 rifampicin
rpoB 762920 c.3114C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 762926 c.-444C>G upstream_gene_variant 0.96 rifampicin
rpoB 762929 c.3123G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 762947 c.-423C>G upstream_gene_variant 0.98 rifampicin
rpoC 762965 c.-405T>C upstream_gene_variant 0.97 rifampicin
rpoC 762971 c.-399G>C upstream_gene_variant 0.97 rifampicin
rpoC 762980 c.-390T>C upstream_gene_variant 0.97 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 0.97 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763005 p.Cys1067Val missense_variant 0.95 rifampicin
rpoC 763022 c.-348C>G upstream_gene_variant 0.99 rifampicin
rpoC 763025 c.-345C>T upstream_gene_variant 0.99 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763053 c.3247T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763074 p.Thr1090Val missense_variant 0.98 rifampicin
rpoB 763088 c.3282C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763109 c.-261C>G upstream_gene_variant 0.95 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763118 p.Glu1104Asp missense_variant 0.94 rifampicin
rpoB 763130 p.Glu1108Asp missense_variant 0.93 rifampicin
rpoC 763133 c.-237G>C upstream_gene_variant 0.92 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 0.92 rifampicin
rpoC 763160 c.-210G>C upstream_gene_variant 0.89 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.83 rifampicin
rpoB 763172 c.3366G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763462 c.93G>C synonymous_variant 0.94 rifampicin
rpoC 763486 c.117T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763507 c.138G>C synonymous_variant 0.94 rifampicin
rpoC 763517 p.Lys50Arg missense_variant 0.95 rifampicin
rpoC 763528 c.159G>C synonymous_variant 0.95 rifampicin
rpoC 763531 c.162G>C synonymous_variant 0.96 rifampicin Not assoc w R
rpoC 763534 c.165T>C synonymous_variant 0.96 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763550 p.Tyr61Ala missense_variant 0.96 rifampicin
rpoC 763570 c.201G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763619 p.Arg84Lys missense_variant 0.97 rifampicin
rpoC 763622 p.Ala85Ser missense_variant 0.98 rifampicin Uncertain significance
rpoC 763633 c.264T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.98 rifampicin
rpoC 763642 c.273G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.97 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.97 rifampicin
rpoC 763709 c.340C>T synonymous_variant 0.95 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 0.93 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.9 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.89 rifampicin
rpoC 764215 c.846A>C synonymous_variant 0.92 rifampicin
rpoC 764216 p.Asn283Asp missense_variant 0.92 rifampicin
rpoC 764227 c.858G>C synonymous_variant 0.96 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>C synonymous_variant 0.97 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.96 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.96 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.96 rifampicin
rpoC 764277 p.Gln303Leu missense_variant 0.96 rifampicin Uncertain significance
rpoC 764291 p.Ser308Asp missense_variant 0.96 rifampicin
rpoC 764297 p.Met310Ala missense_variant 0.96 rifampicin
rpoC 764301 p.Gly311Ala missense_variant 1.0 rifampicin
rpoC 764308 c.939G>C synonymous_variant 1.0 rifampicin
rpoC 764315 p.Ala316Cys missense_variant 1.0 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>T synonymous_variant 1.0 rifampicin
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764383 c.1014C>G synonymous_variant 1.0 rifampicin
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764410 c.1041G>C synonymous_variant 1.0 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGC synonymous_variant 1.0 rifampicin
rpoC 764438 p.Leu357Met missense_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.85 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764470 c.1101C>G synonymous_variant 1.0 rifampicin
rpoC 764485 c.1116G>C synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764503 c.1134G>C synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764560 c.1191T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764581 c.1212T>C synonymous_variant 0.99 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>C synonymous_variant 0.99 rifampicin
rpoC 764623 c.1254C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>A synonymous_variant 0.99 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764660 p.Val431Ile missense_variant 0.98 rifampicin
rpoC 764695 c.1326T>C synonymous_variant 0.97 rifampicin
rpoC 764713 c.1344G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764731 c.1362G>C synonymous_variant 0.96 rifampicin
rpoC 764737 c.1368G>C synonymous_variant 0.95 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764863 c.1494G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>C synonymous_variant 0.95 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.96 rifampicin
rpoC 764911 c.1542A>C synonymous_variant 0.95 rifampicin
rpoC 764912 p.Met515Val missense_variant 0.95 rifampicin
rpoC 764917 c.1548G>C synonymous_variant 0.95 rifampicin
rpoC 764920 c.1551G>C synonymous_variant 0.95 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.97 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764952 p.Val528Ala missense_variant 0.96 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765004 c.1635G>C synonymous_variant 0.97 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1643delAGinsTC synonymous_variant 0.97 rifampicin
rpoC 765016 c.1647C>G synonymous_variant 1.0 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>C synonymous_variant 1.0 rifampicin
rpoC 765082 c.1713G>A synonymous_variant 1.0 rifampicin
rpoC 765083 p.Arg572Lys missense_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765115 c.1746G>C synonymous_variant 1.0 rifampicin
rpoC 765121 c.1752G>C synonymous_variant 1.0 rifampicin
rpoC 766291 c.2922G>C synonymous_variant 1.0 rifampicin
rpoC 766297 c.2928G>C synonymous_variant 1.0 rifampicin
rpoC 766309 c.2940G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766331 p.Leu988Met missense_variant 0.93 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.97 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766354 c.2985C>G synonymous_variant 0.97 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.97 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 0.97 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.97 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.93 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766423 c.3054T>C synonymous_variant 0.96 rifampicin
rpoC 766432 c.3063T>C synonymous_variant 0.95 rifampicin
rpoC 766434 p.Glu1022Gly missense_variant 0.94 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.93 rifampicin
rplC 800633 c.-176T>C upstream_gene_variant 0.92 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.94 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.94 linezolid
rplC 800672 c.-137G>C upstream_gene_variant 0.94 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 1.0 linezolid
rplC 800702 c.-107G>C upstream_gene_variant 0.94 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.94 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 0.94 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.94 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.94 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.94 linezolid
rplC 800726 c.-83G>C upstream_gene_variant 0.94 linezolid
rplC 800744 c.-65G>T upstream_gene_variant 0.89 linezolid
rplC 800768 c.-41C>G upstream_gene_variant 0.82 linezolid
rplC 800769 c.-40_-39delAGinsTC upstream_gene_variant 0.81 linezolid
rrs 1471918 n.73A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471927 n.82_85delTTCGinsAGCTTGCT non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471938 n.93T>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471972 n.127T>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471979 n.134T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>G non_coding_transcript_exon_variant 0.99 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472030 n.185_197delGGGATGCATGTCTinsACCGTGAGGG non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472054 n.210_212delCGC non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472062 n.217G>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472123 n.278A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472150 n.305T>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472225 n.380C>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472278 n.433C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472279 n.434T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472299 n.455_462delCCGGGTTC non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472309 n.464C>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472311 n.467_470delGGAT non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472325 n.480G>A non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472447 n.602C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472485 n.640delGinsTA non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472670 n.825_831delGGGTTTCinsAGGGGT non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472685 n.840G>A non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472686 n.841G>C non_coding_transcript_exon_variant 0.99 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472690 n.845C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 0.99 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472837 n.992C>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472840 n.995A>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472845 n.1000G>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472846 n.1001C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472861 n.1016G>C non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472874 n.1029C>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472875 n.1030T>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472878 n.1033G>A non_coding_transcript_exon_variant 0.99 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472993 n.1148G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473089 n.1244A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473123 n.1278A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473292 n.1447_1449delGGAinsTGGG non_coding_transcript_exon_variant 0.99 kanamycin
capreomycin
streptomycin
amikacin
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474178 n.522dupC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474184 n.527_529delCGAinsG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474200 n.545delT non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474285 n.630_631delTC non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1474289 n.632C>T non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474292 n.635_651delTTCCTCTCCGGAGGAGGinsGT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474399 n.742G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474439 n.782A>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474487 n.830G>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474497 n.840G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474517 n.860C>G non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474628 n.971C>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474798 n.1141C>G non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474801 n.1144G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474825 n.1168G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474921 n.1264C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474934 n.1277C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475696 n.2039T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475699 n.2042delCinsGT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475703 n.2046A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475759 n.2102C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475761 n.2106_2110delCAAGG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475769 n.2112_2113insTTTGCCGGCC non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476087 n.2430C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476100 n.2443A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476116 n.2459A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476276 n.2619C>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476523 n.2867delC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476624 n.2967T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476665 n.3008T>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476666 n.3009C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476670 n.3013A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rpsA 1833668 p.Ile43Val missense_variant 0.71 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.71 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 0.71 pyrazinamide
rpsA 1833682 c.141C>T synonymous_variant 0.71 pyrazinamide
rpsA 1833685 c.144G>C synonymous_variant 0.71 pyrazinamide
rpsA 1833688 c.147C>T synonymous_variant 0.73 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.76 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.79 pyrazinamide
rpsA 1833718 c.177C>G synonymous_variant 0.85 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.85 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.88 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.86 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.86 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
rpsA 1833770 p.Asn77Asp missense_variant 0.91 pyrazinamide
rpsA 1833778 c.237C>G synonymous_variant 0.92 pyrazinamide
rpsA 1833781 c.240T>C synonymous_variant 0.91 pyrazinamide
rpsA 1833782 p.Ser81Glu missense_variant 0.91 pyrazinamide
rpsA 1833797 p.Val86Ile missense_variant 0.95 pyrazinamide Uncertain significance
rpsA 1833802 p.Glu87Asp missense_variant 0.95 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.96 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.96 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.97 pyrazinamide
rpsA 1833859 c.318C>T synonymous_variant 0.97 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833894 p.Ala118Asp missense_variant 0.98 pyrazinamide
rpsA 1833914 p.Ala125Pro missense_variant 0.97 pyrazinamide
rpsA 1833921 p.Lys127Thr missense_variant 0.95 pyrazinamide
rpsA 1833925 c.384C>T synonymous_variant 0.95 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.95 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.96 pyrazinamide
rpsA 1833961 c.420C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.96 pyrazinamide
rpsA 1833988 c.447C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.95 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.94 pyrazinamide
rpsA 1834040 p.Lys167Gln missense_variant 0.95 pyrazinamide
rpsA 1834046 p.Ile169Leu missense_variant 0.94 pyrazinamide
rpsA 1834054 c.513C>G synonymous_variant 0.94 pyrazinamide
rpsA 1834093 c.552G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834105 c.564C>T synonymous_variant 0.96 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.96 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834135 c.594G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834139 c.598_599delAGinsTC synonymous_variant 1.0 pyrazinamide
rpsA 1834151 p.Asn204His missense_variant 1.0 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 1.0 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834167 c.628_629delAC frameshift_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834172 c.631_632insGG frameshift_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834183 c.642T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834195 c.654G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834252 c.711C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834276 c.735C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834294 c.753G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834327 c.786G>T synonymous_variant 0.83 pyrazinamide
rpsA 1834333 p.Asp264Glu missense_variant 0.75 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.92 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.94 pyrazinamide
rpsA 1834486 c.945G>A synonymous_variant 0.82 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834504 c.963G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834534 c.993C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834537 p.Glu332Asp missense_variant 0.96 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.96 pyrazinamide
rpsA 1834550 p.Val337Ile missense_variant 0.98 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834556 p.Ala339Thr missense_variant 0.98 pyrazinamide Uncertain significance
rpsA 1834567 p.Asp342Glu missense_variant 0.98 pyrazinamide
rpsA 1834570 p.Asp343Glu missense_variant 0.98 pyrazinamide
rpsA 1834573 c.1032G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834603 p.Glu354Asp missense_variant 0.98 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834627 c.1086C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.97 pyrazinamide
rpsA 1834637 p.Asn366Asp missense_variant 0.97 pyrazinamide
rpsA 1834647 p.Tyr369Phe missense_variant 0.97 pyrazinamide
rpsA 1834667 p.Ala376Thr missense_variant 0.98 pyrazinamide
rpsA 1834683 p.Ala381Gly missense_variant 1.0 pyrazinamide
rpsA 1834687 c.1146C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834688 c.1147_1148delAGinsTC synonymous_variant 1.0 pyrazinamide
rpsA 1834720 c.1179C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834735 c.1194C>G synonymous_variant 0.94 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.94 pyrazinamide
rpsA 1834747 c.1206A>G synonymous_variant 0.92 pyrazinamide
Rv2477c 2782537 c.1506T>G synonymous_variant 0.91 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.91 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782546 c.1497C>T synonymous_variant 0.91 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782549 c.1494T>C synonymous_variant 0.91 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782558 c.1485T>C synonymous_variant 0.91 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782561 c.1482G>C synonymous_variant 0.91 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782576 c.1467C>G synonymous_variant 0.91 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
clpC1 4038719 c.1986G>C synonymous_variant 0.69 pyrazinamide
clpC1 4038725 c.1980C>G synonymous_variant 0.78 pyrazinamide
clpC1 4038743 p.Thr654Val missense_variant 0.82 pyrazinamide
clpC1 4038756 p.Gly650Ala missense_variant 0.86 pyrazinamide
clpC1 4038758 c.1947C>T synonymous_variant 0.88 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 0.89 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.89 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.9 pyrazinamide
clpC1 4038791 c.1914G>C synonymous_variant 0.82 pyrazinamide
clpC1 4038794 p.Ser637Thr missense_variant 0.82 pyrazinamide
clpC1 4038811 p.Gln632Lys missense_variant 0.89 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.89 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.82 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
clpC1 4038905 c.1800A>C synonymous_variant 0.98 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.98 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.98 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.98 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.98 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.98 pyrazinamide
clpC1 4038926 c.1779G>C synonymous_variant 0.98 pyrazinamide
clpC1 4038932 c.1773G>C synonymous_variant 0.99 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038980 c.1725C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038983 p.Asp574Glu missense_variant 1.0 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039001 p.Asn568Ala missense_variant 1.0 pyrazinamide
clpC1 4039007 c.1698G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.98 pyrazinamide
clpC1 4039025 c.1680C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.93 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 0.75 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039714 p.Tyr331His missense_variant 1.0 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039805 c.900C>T synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4039817 c.888A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039820 c.885T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039823 c.882T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 1.0 pyrazinamide
clpC1 4039838 p.Leu289Ile missense_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039871 p.Thr278Gln missense_variant 1.0 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039916 c.789T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.93 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.95 pyrazinamide
clpC1 4039955 c.750G>T synonymous_variant 0.9 pyrazinamide
clpC1 4039960 p.Thr249Ser missense_variant 0.88 pyrazinamide
clpC1 4039964 c.741C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.83 pyrazinamide
clpC1 4039982 c.723G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 0.8 pyrazinamide
clpC1 4040010 p.Ala232Asp missense_variant 0.8 pyrazinamide Uncertain significance
clpC1 4040013 p.Gln231Leu missense_variant 0.8 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 0.8 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.82 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.85 pyrazinamide
clpC1 4040045 c.660C>G synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4040063 c.642G>C synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
clpC1 4040087 c.618G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040306 c.399G>C synonymous_variant 0.7 pyrazinamide
clpC1 4040309 p.Thr132Pro missense_variant 0.7 pyrazinamide
clpC1 4040315 p.Glu130Asp missense_variant 0.7 pyrazinamide
clpC1 4040324 c.381G>C synonymous_variant 0.7 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.9 pyrazinamide
clpC1 4040363 c.342A>C synonymous_variant 0.9 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.9 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 0.9 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.9 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.9 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.9 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim