Run ID: ERR4817060
Sample name:
Date: 2024-05-22T19:03:23.892695
Number of reads: 866769
Percentage reads mapped: 36.92
Median coverage: 19.0
Strain:
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | ||||
pyrazinamide | ||||
streptomycin | rrs | n.888G>A | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | fgd1 | c.412_414delCTAinsTG | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
fbiC | c.604_606delTCGinsGC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
c.859_861delATCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
fgd1 | 491194 | c.412_414delCTAinsTG | frameshift_variant&stop_gained | 0.36 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303534 | c.604_606delTCGinsGC | frameshift_variant&missense_variant | 0.41 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303789 | c.859_861delATCinsGG | frameshift_variant&missense_variant | 0.29 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rrs | 1472733 | n.888G>A | non_coding_transcript_exon_variant | 0.53 | streptomycin | Uncertain significance | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 30 | c.30C>G | synonymous_variant | 0.41 | isoniazid | |
dnaA | 42 | c.42C>T | synonymous_variant | 0.5 | isoniazid | |
dnaA | 786 | c.786C>T | synonymous_variant | 0.35 | isoniazid | |
dnaA | 795 | c.795A>C | synonymous_variant | 0.32 | isoniazid | Not assoc w R - Interim |
dnaA | 897 | c.897A>G | synonymous_variant | 0.33 | isoniazid | |
dnaA | 909 | c.909A>C | synonymous_variant | 0.33 | isoniazid | Not assoc w R - Interim |
dnaA | 912 | c.912T>G | synonymous_variant | 0.33 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 0.37 | isoniazid | |
dnaA | 921 | c.921A>G | synonymous_variant | 0.4 | isoniazid | Not assoc w R - Interim |
dnaA | 942 | c.942C>G | synonymous_variant | 0.35 | isoniazid | |
dnaA | 945 | c.945G>A | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1395 | c.1395G>C | synonymous_variant | 0.3 | isoniazid | |
dnaA | 1404 | c.1404T>C | synonymous_variant | 0.37 | isoniazid | |
dnaA | 1407 | c.1407T>C | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1413 | c.1413A>C | synonymous_variant | 0.39 | isoniazid | |
dnaA | 1416 | c.1416C>G | synonymous_variant | 0.38 | isoniazid | |
dnaA | 1428 | c.1428C>G | synonymous_variant | 0.44 | isoniazid | |
dnaA | 1449 | c.1449G>A | synonymous_variant | 0.43 | isoniazid | |
dnaA | 1461 | c.1461C>G | synonymous_variant | 0.5 | isoniazid | |
dnaA | 1470 | c.1470C>T | synonymous_variant | 0.47 | isoniazid | |
dnaA | 1485 | c.1485A>G | synonymous_variant | 0.47 | isoniazid | |
dnaA | 1488 | c.1488A>G | synonymous_variant | 0.47 | isoniazid | |
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6289 | c.1050C>T | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.53 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 6362 | c.-940T>C | upstream_gene_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6376 | c.-926G>A | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6379 | c.-923C>G | upstream_gene_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6382 | c.-920A>G | upstream_gene_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6388 | c.-914T>C | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6643 | c.-659A>G | upstream_gene_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6649 | c.-653T>C | upstream_gene_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6655 | c.-647T>C | upstream_gene_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6742 | c.-560A>G | upstream_gene_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6982 | c.-320A>C | upstream_gene_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7006 | c.-296T>C | upstream_gene_variant | 0.6 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7007 | c.-295C>T | upstream_gene_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7010 | c.-292C>T | upstream_gene_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7015 | c.-287G>A | upstream_gene_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7018 | c.-284G>A | upstream_gene_variant | 0.63 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7023 | p.Leu595Gln | missense_variant | 0.67 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7033 | c.-269G>C | upstream_gene_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7051 | p.Glu604Asp | missense_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7066 | c.-236G>C | upstream_gene_variant | 0.54 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7178 | c.-124T>C | upstream_gene_variant | 0.71 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7186 | c.1947C>G | synonymous_variant | 0.67 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 7216 | c.1977G>C | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 7234 | c.1995C>T | synonymous_variant | 0.41 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7324 | c.23_24insAGG | disruptive_inframe_insertion | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7334 | c.33G>C | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7335 | p.Leu12Val | missense_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7347 | c.46_48delGAAinsCG | frameshift_variant&missense_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7361 | c.60C>T | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7391 | c.90C>T | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7394 | c.93T>C | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7427 | c.126G>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7442 | c.141G>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7451 | c.150C>G | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7477 | p.Met59Thr | missense_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7523 | c.222C>G | synonymous_variant | 0.52 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7532 | c.231T>G | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7547 | c.246C>T | synonymous_variant | 0.6 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7571 | c.270G>C | synonymous_variant | 0.72 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 0.67 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7595 | c.294C>G | synonymous_variant | 0.62 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7601 | c.300C>G | synonymous_variant | 0.59 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7607 | c.306C>T | synonymous_variant | 0.6 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7622 | c.321C>T | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7625 | c.324G>C | synonymous_variant | 0.58 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7631 | c.330G>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7637 | c.336C>G | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8156 | c.855T>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 0.44 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8225 | c.924T>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8234 | c.933T>C | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8237 | c.936A>G | synonymous_variant | 0.53 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8247 | c.946_948delATCinsGG | frameshift_variant&missense_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.65 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8330 | c.1029C>G | synonymous_variant | 0.57 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8339 | c.1038A>G | synonymous_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8340 | p.Ala347Ser | missense_variant | 0.61 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8372 | c.1071G>C | synonymous_variant | 0.57 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 0.57 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8382 | p.Leu361Met | missense_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8387 | c.1086C>T | synonymous_variant | 0.62 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8391 | c.1090_1092delTATinsCC | frameshift_variant&missense_variant | 0.59 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8399 | c.1098T>G | synonymous_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8401 | p.Asp367Ala | missense_variant | 0.61 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8405 | c.1104C>T | synonymous_variant | 0.65 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8420 | c.1119T>C | synonymous_variant | 0.64 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8588 | c.1287G>A | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8597 | c.1296C>G | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8603 | c.1302A>G | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8619 | c.1318_1320delTTGinsCA | frameshift_variant&missense_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8624 | c.1323G>C | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.42 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8678 | c.1377G>A | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8693 | c.1392T>C | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8696 | c.1395G>C | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8699 | c.1398A>G | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8714 | c.1413A>G | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8730 | p.Gly477Arg | missense_variant | 0.43 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrA | 9252 | p.Val651Ile | missense_variant | 0.32 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9291 | c.1990C>T | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.47 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9299 | c.1998G>C | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9300 | p.Ala667Ser | missense_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 0.38 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9308 | p.Asp669Glu | missense_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9323 | c.2022C>G | synonymous_variant | 0.5 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9335 | c.2034G>C | synonymous_variant | 0.5 | levofloxacin | |
moxifloxacin | ||||||
Rv0010c | 13788 | c.-230C>G | upstream_gene_variant | 0.94 | isoniazid | |
fgd1 | 490812 | c.30A>G | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490815 | c.33G>C | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490827 | c.45C>T | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490848 | c.66A>G | synonymous_variant | 0.39 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 490851 | c.69A>T | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490868 | p.Ala29Gly | missense_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490887 | c.105G>A | synonymous_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490890 | c.108C>G | synonymous_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490896 | c.114C>T | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490905 | c.123T>C | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491151 | c.369G>A | synonymous_variant | 0.55 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491173 | c.391C>A | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491181 | c.399T>C | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491184 | c.402A>G | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491191 | p.Gly137Arg | missense_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491202 | c.420G>C | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491203 | p.Gln141Glu | missense_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491212 | p.Ser144Arg | missense_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491217 | c.435T>C | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491601 | c.819T>C | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491610 | c.828A>G | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491616 | c.834A>G | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491620 | p.Ile280Val | missense_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491643 | c.861G>A | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491646 | c.864G>C | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491649 | c.867C>T | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491658 | c.876A>G | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491661 | c.879C>G | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491673 | c.891A>C | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491676 | c.894T>C | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491679 | c.897A>G | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
mshA | 575812 | c.465C>T | synonymous_variant | 0.42 | ethionamide | |
isoniazid | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.38 | ethionamide | |
isoniazid | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 0.38 | ethionamide | |
isoniazid | ||||||
mshA | 575830 | c.483C>G | synonymous_variant | 0.37 | ethionamide | |
isoniazid | ||||||
mshA | 575833 | c.486C>G | synonymous_variant | 0.38 | ethionamide | |
isoniazid | ||||||
mshA | 575845 | c.498C>T | synonymous_variant | 0.4 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575884 | c.537G>C | synonymous_variant | 0.36 | ethionamide | |
isoniazid | ||||||
mshA | 575887 | c.540G>C | synonymous_variant | 0.38 | ethionamide | |
isoniazid | ||||||
mshA | 575893 | c.546C>G | synonymous_variant | 0.39 | ethionamide | |
isoniazid | ||||||
mshA | 575896 | c.549G>C | synonymous_variant | 0.36 | ethionamide | |
isoniazid | ||||||
mshA | 575905 | c.558G>C | synonymous_variant | 0.34 | ethionamide | |
isoniazid | ||||||
ccsA | 619543 | c.-348C>G | upstream_gene_variant | 0.38 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619552 | c.-339A>G | upstream_gene_variant | 0.43 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619555 | c.-336C>G | upstream_gene_variant | 0.43 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619561 | c.-330G>C | upstream_gene_variant | 0.46 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619570 | c.-321G>C | upstream_gene_variant | 0.5 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619574 | c.-317G>A | upstream_gene_variant | 0.52 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619579 | c.-312G>C | upstream_gene_variant | 0.52 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619584 | c.-307A>T | upstream_gene_variant | 0.48 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619591 | c.-300G>C | upstream_gene_variant | 0.48 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619609 | c.-282G>T | upstream_gene_variant | 0.44 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619634 | c.-257T>A | upstream_gene_variant | 0.36 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620254 | c.364_366delCTCinsTG | frameshift_variant&missense_variant | 0.25 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620265 | c.375C>G | synonymous_variant | 0.3 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620268 | c.378G>C | synonymous_variant | 0.32 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620283 | c.393T>C | synonymous_variant | 0.31 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620284 | c.394_396delGCGinsCC | frameshift_variant&missense_variant | 0.29 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620288 | p.Arg133Gln | missense_variant | 0.29 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620295 | c.405G>T | synonymous_variant | 0.33 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 0.31 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620367 | c.477T>C | synonymous_variant | 0.32 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620373 | c.483C>G | synonymous_variant | 0.34 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620376 | c.486G>C | synonymous_variant | 0.38 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620385 | c.495G>C | synonymous_variant | 0.36 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620388 | c.498A>G | synonymous_variant | 0.36 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620389 | c.499C>T | synonymous_variant | 0.36 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620412 | c.522T>C | synonymous_variant | 0.32 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620415 | c.525T>C | synonymous_variant | 0.3 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620421 | c.531G>C | synonymous_variant | 0.32 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620424 | c.534G>C | synonymous_variant | 0.32 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
Rv0565c | 656265 | c.1204_1205delAC | frameshift_variant | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 656448 | c.1021_1023delATTinsGC | frameshift_variant&missense_variant | 0.33 | ethionamide | Uncertain significance |
Rv0565c | 656454 | c.1017G>C | synonymous_variant | 0.36 | ethionamide | |
Rv0565c | 656457 | c.1014T>C | synonymous_variant | 0.35 | ethionamide | |
Rv0565c | 656469 | c.1002T>C | synonymous_variant | 0.36 | ethionamide | |
Rv0565c | 656475 | c.996A>G | synonymous_variant | 0.39 | ethionamide | |
Rv0565c | 656484 | c.987T>C | synonymous_variant | 0.33 | ethionamide | |
Rv0565c | 656487 | c.984T>C | synonymous_variant | 0.33 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656493 | c.978C>G | synonymous_variant | 0.33 | ethionamide | |
Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 0.69 | ethionamide | |
Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 0.52 | ethionamide | |
Rv0565c | 657678 | c.-209_-208delAAinsTC | upstream_gene_variant | 0.47 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAC | upstream_gene_variant | 0.53 | ethionamide | |
Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 0.53 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 0.4 | ethionamide | |
hadA | 732295 | c.366G>C | synonymous_variant | 0.47 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 0.5 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.5 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.52 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 0.52 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 0.53 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.53 | isoniazid | |
nusG | 734370 | c.117A>G | synonymous_variant | 0.4 | rifampicin | |
nusG | 734376 | c.123G>A | synonymous_variant | 0.38 | rifampicin | |
nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 0.5 | rifampicin | |
nusG | 734421 | c.168A>G | synonymous_variant | 0.56 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 0.65 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 0.59 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.56 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.53 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.55 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
nusG | 734532 | c.279A>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
nusG | 734556 | c.303C>T | synonymous_variant | 0.64 | rifampicin | |
nusG | 734559 | c.306T>C | synonymous_variant | 0.62 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 760091 | c.285G>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 760101 | c.295T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 760112 | c.306T>C | synonymous_variant | 0.53 | rifampicin | |
rpoB | 760118 | c.312T>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.5 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.67 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 760298 | c.492G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.58 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.54 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.58 | rifampicin | |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.64 | rifampicin | |
rpoB | 760412 | c.606C>G | synonymous_variant | 0.69 | rifampicin | |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.69 | rifampicin | Not assoc w R - Interim |
rpoB | 760487 | c.681G>C | synonymous_variant | 0.6 | rifampicin | |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.54 | rifampicin | Uncertain significance |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.75 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.71 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.7 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.73 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.47 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 760931 | c.1125C>G | synonymous_variant | 0.44 | rifampicin | |
rpoB | 760934 | c.1128C>T | synonymous_variant | 0.44 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.52 | rifampicin | |
rpoB | 761006 | c.1200C>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.45 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 761132 | c.1326G>T | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327T>C | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoB | 761153 | c.1347G>C | synonymous_variant | 0.38 | rifampicin | |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoB | 761207 | c.1401C>T | synonymous_variant | 0.44 | rifampicin | |
rpoB | 761213 | c.1407G>C | synonymous_variant | 0.5 | rifampicin | |
rpoB | 761219 | c.1413G>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 761306 | c.1500C>G | synonymous_variant | 0.39 | rifampicin | |
rpoB | 761312 | c.1506G>C | synonymous_variant | 0.36 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 761330 | c.1524G>C | synonymous_variant | 0.41 | rifampicin | |
rpoB | 761408 | c.1602G>C | synonymous_variant | 0.5 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.41 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 761588 | c.1782C>T | synonymous_variant | 0.41 | rifampicin | |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.43 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.43 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 761675 | c.1869G>C | synonymous_variant | 0.48 | rifampicin | |
rpoB | 761747 | c.1941G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761792 | c.1986T>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.42 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 0.35 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.35 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.4 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.4 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.4 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 762008 | c.2202C>T | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.55 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoB | 762032 | c.2226C>T | synonymous_variant | 0.53 | rifampicin | |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.45 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.35 | rifampicin | |
rpoB | 762134 | c.2328C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.42 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.46 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoB | 762799 | p.Ala998Gly | missense_variant | 0.47 | rifampicin | Uncertain significance |
rpoB | 762810 | c.3004_3006delGCCinsTG | frameshift_variant&missense_variant | 0.47 | rifampicin | |
rpoB | 762813 | p.Met1003Val | missense_variant | 0.47 | rifampicin | |
rpoB | 762818 | c.3012C>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoB | 762827 | c.3021G>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 762926 | c.-444C>G | upstream_gene_variant | 0.26 | rifampicin | |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 762938 | c.-432G>C | upstream_gene_variant | 0.26 | rifampicin | |
rpoB | 762962 | c.3156C>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 762983 | c.-387C>T | upstream_gene_variant | 0.19 | rifampicin | |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.72 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoC | 763013 | c.-357C>G | upstream_gene_variant | 0.48 | rifampicin | |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoB | 763136 | c.3330C>T | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.6 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.5 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 763190 | c.-180C>T | upstream_gene_variant | 0.6 | rifampicin | |
rpoC | 763202 | c.-168A>G | upstream_gene_variant | 0.46 | rifampicin | |
rpoC | 763205 | c.-165G>C | upstream_gene_variant | 0.5 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 0.5 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.55 | rifampicin | |
rpoB | 763227 | c.3421C>T | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoB | 763238 | c.3432T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763622 | p.Ala85Ser | missense_variant | 0.21 | rifampicin | Uncertain significance |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.59 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 763699 | c.330G>T | synonymous_variant | 0.32 | rifampicin | |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763708 | c.339G>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 763714 | c.345G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.66 | rifampicin | Not assoc w R - Interim |
rpoC | 763718 | p.Leu117Val | missense_variant | 0.39 | rifampicin | |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.64 | rifampicin | |
rpoC | 763724 | p.Asp119Asn | missense_variant | 0.39 | rifampicin | |
rpoC | 763729 | c.360G>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.61 | rifampicin | |
rpoC | 763735 | c.366G>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.19 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.59 | rifampicin | |
rpoC | 763751 | p.Ile128Val | missense_variant | 0.47 | rifampicin | |
rpoC | 763772 | c.403_405delGTGinsAC | frameshift_variant&missense_variant | 0.37 | rifampicin | |
rpoC | 764059 | c.690G>T | synonymous_variant | 0.5 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.52 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 764102 | p.Val245Ile | missense_variant | 0.64 | rifampicin | |
rpoC | 764112 | p.Tyr248Phe | missense_variant | 0.54 | rifampicin | |
rpoC | 764116 | c.747C>T | synonymous_variant | 0.58 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.53 | rifampicin | |
rpoC | 764140 | c.771C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 764236 | c.867G>A | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764248 | c.879C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764419 | c.1050C>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764428 | c.1059G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764489 | c.1120C>T | synonymous_variant | 0.47 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 764510 | c.1141_1143delCTGinsTC | frameshift_variant&missense_variant | 0.31 | rifampicin | |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764530 | c.1161C>T | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.82 | rifampicin | |
rpoC | 764543 | c.1174_1176delACCinsGG | frameshift_variant&missense_variant | 0.5 | rifampicin | |
rpoC | 764548 | c.1179G>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764573 | c.1204_1206delCTTinsAC | frameshift_variant&missense_variant | 0.44 | rifampicin | |
rpoC | 764578 | c.1209C>G | synonymous_variant | 0.46 | rifampicin | |
rpoC | 764581 | c.1212T>C | synonymous_variant | 0.68 | rifampicin | |
rpoC | 764582 | p.Leu405Met | missense_variant | 0.46 | rifampicin | |
rpoC | 764593 | c.1224C>T | synonymous_variant | 0.7 | rifampicin | |
rpoC | 764602 | c.1233C>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.41 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.5 | rifampicin | |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.57 | rifampicin | Not assoc w R - Interim |
rpoC | 764935 | c.1566T>C | synonymous_variant | 0.59 | rifampicin | |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.65 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 765034 | c.1665T>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 765040 | c.1671T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 765053 | c.1684_1685delTCinsAG | synonymous_variant | 0.37 | rifampicin | |
rpoC | 765073 | c.1704G>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 765076 | c.1707A>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 765079 | c.1710T>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 765082 | c.1713G>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 765089 | c.1720T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 765292 | c.1923G>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 765298 | c.1929G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 765300 | p.Val644Ala | missense_variant | 0.33 | rifampicin | Uncertain significance |
rpoC | 765319 | c.1950A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765326 | p.His653Ala | missense_variant | 0.31 | rifampicin | Uncertain significance |
rpoC | 765329 | p.Ser654Gly | missense_variant | 0.32 | rifampicin | |
rpoC | 765346 | c.1977C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765349 | c.1980T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 765352 | c.1983G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.38 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 0.48 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.54 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.56 | rifampicin | Not assoc w R - Interim |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 765529 | c.2160C>T | synonymous_variant | 0.45 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.45 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 765580 | c.2211G>C | synonymous_variant | 0.43 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.43 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.36 | rifampicin | |
rpoC | 765850 | c.2481G>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 765937 | c.2568T>C | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.64 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>G | synonymous_variant | 0.56 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.62 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 0.62 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.52 | rifampicin | |
rpoC | 766054 | c.2685C>G | synonymous_variant | 0.46 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.42 | rifampicin | |
rpoC | 766096 | c.2727G>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766135 | c.2766G>A | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 766345 | c.2976T>C | synonymous_variant | 0.58 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 766357 | c.2988C>T | synonymous_variant | 0.54 | rifampicin | |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.58 | rifampicin | |
rpoC | 766366 | c.2997C>G | synonymous_variant | 0.53 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.61 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.67 | rifampicin | |
rpoC | 766408 | c.3039C>G | synonymous_variant | 0.55 | rifampicin | |
rpoC | 766411 | c.3042C>G | synonymous_variant | 0.58 | rifampicin | |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.59 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 766462 | c.3093G>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 766484 | c.3115_3117delGTAinsAC | frameshift_variant&missense_variant | 0.52 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.5 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 766531 | c.3162G>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766540 | p.Asp1057Glu | missense_variant | 0.44 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 766630 | c.3261G>C | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766673 | p.Gly1102Asn | missense_variant | 0.38 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 766747 | c.3378C>T | synonymous_variant | 0.56 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.62 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.64 | rifampicin | |
rpoC | 766801 | c.3432C>G | synonymous_variant | 0.52 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 766885 | c.3516G>A | synonymous_variant | 0.45 | rifampicin | |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.39 | rifampicin | |
rpoC | 767158 | c.3789T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.34 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 767212 | c.3843G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 767263 | c.3894T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 767264 | p.Ala1299Gln | missense_variant | 0.35 | rifampicin | |
rpoC | 767275 | c.3906T>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 767278 | c.3909T>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 767281 | c.3912C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 767284 | c.3915C>T | synonymous_variant | 0.33 | rifampicin | |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781595 | c.36T>C | synonymous_variant | 0.47 | streptomycin | |
rpsL | 781605 | p.Ile16Val | missense_variant | 0.42 | streptomycin | Uncertain significance |
rpsL | 781608 | p.Ser17Ala | missense_variant | 0.44 | streptomycin | |
rpsL | 781628 | c.69T>C | synonymous_variant | 0.46 | streptomycin | Not assoc w R - Interim |
rpsL | 781631 | c.72G>C | synonymous_variant | 0.48 | streptomycin | |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.54 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.54 | streptomycin | |
rpsL | 781700 | c.141G>C | synonymous_variant | 0.48 | streptomycin | |
rpsL | 781703 | c.144G>T | synonymous_variant | 0.47 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.38 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.4 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.43 | streptomycin | |
rpsL | 781742 | c.183C>T | synonymous_variant | 0.43 | streptomycin | |
rpsL | 781748 | c.189C>G | synonymous_variant | 0.48 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.45 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.48 | streptomycin | |
rpsL | 781772 | c.213C>A | synonymous_variant | 0.44 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 0.6 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.48 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 0.35 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.41 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.29 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.33 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.36 | streptomycin | |
rpsL | 781877 | c.318T>C | synonymous_variant | 0.37 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.38 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.32 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.38 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.32 | streptomycin | Uncertain significance |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.42 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.48 | linezolid | |
rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.52 | linezolid | |
rplC | 800648 | c.-161A>T | upstream_gene_variant | 0.53 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.62 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.76 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.62 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.57 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.59 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.59 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.52 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.4 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 0.33 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 0.33 | linezolid | |
rplC | 801300 | c.492C>G | synonymous_variant | 0.25 | linezolid | |
rplC | 801309 | c.501C>G | synonymous_variant | 0.26 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 0.27 | linezolid | |
rplC | 801321 | c.513C>T | synonymous_variant | 0.26 | linezolid | Not assoc w R - Interim |
rplC | 801348 | c.540T>G | synonymous_variant | 0.25 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 0.26 | linezolid | |
rplC | 801367 | p.Ala187Thr | missense_variant | 0.34 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 0.29 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 0.29 | linezolid | |
rplC | 801438 | c.630T>C | synonymous_variant | 0.25 | linezolid | |
rplC | 801442 | p.Ile212Val | missense_variant | 0.27 | linezolid | |
fbiC | 1303501 | c.571C>T | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303509 | c.579G>C | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303512 | c.582T>C | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303521 | c.591C>T | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303530 | c.600G>A | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303539 | c.609G>C | synonymous_variant | 0.45 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.45 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303632 | c.702T>G | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303728 | c.798G>A | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303785 | c.855G>C | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303797 | c.867A>G | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303842 | c.912C>G | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303845 | c.915C>G | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303866 | p.Glu312Asp | missense_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303867 | p.Asp313Asn | missense_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303905 | c.975G>C | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 0.45 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303920 | c.990C>T | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303944 | c.1014G>C | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303947 | c.1017T>G | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303953 | p.Asp341Glu | missense_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303956 | c.1026A>G | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303961 | p.Arg344Leu | missense_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303971 | c.1041T>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303980 | c.1050G>A | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303998 | c.1068T>G | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304004 | c.1074A>G | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.48 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304613 | c.1683T>C | synonymous_variant | 0.62 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.58 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.5 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.45 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304658 | c.1728C>G | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304661 | c.1731C>T | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304787 | c.1857T>G | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.52 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.52 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.52 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.55 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304832 | c.1902C>T | synonymous_variant | 0.55 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304869 | c.1939C>T | synonymous_variant | 0.93 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304875 | p.Ile649Val | missense_variant | 0.83 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304883 | p.Glu651Asp | missense_variant | 0.79 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304891 | p.Ile654Thr | missense_variant | 0.78 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.78 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304907 | c.1977C>G | synonymous_variant | 0.71 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304910 | c.1980G>C | synonymous_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.7 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.76 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.71 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.68 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304983 | c.2053C>T | synonymous_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304995 | p.Leu689Met | missense_variant | 0.63 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305006 | c.2076A>G | synonymous_variant | 0.67 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305012 | c.2082G>C | synonymous_variant | 0.69 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305015 | c.2085G>C | synonymous_variant | 0.69 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305384 | c.2454G>C | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305396 | c.2466C>G | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305405 | c.2475A>G | synonymous_variant | 0.37 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305417 | c.2487C>G | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305423 | c.2493T>C | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305430 | p.Val834Thr | missense_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305444 | c.2514A>G | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
atpE | 1461170 | c.126A>G | synonymous_variant | 0.65 | bedaquiline | |
atpE | 1461185 | c.141G>T | synonymous_variant | 0.63 | bedaquiline | |
atpE | 1461197 | c.153A>G | synonymous_variant | 0.65 | bedaquiline | |
atpE | 1461219 | c.175T>C | synonymous_variant | 0.59 | bedaquiline | |
atpE | 1461233 | c.189A>C | synonymous_variant | 0.48 | bedaquiline | |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 0.67 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.67 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 0.55 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.55 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.89 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472078 | n.233C>T | non_coding_transcript_exon_variant | 0.89 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472122 | n.277G>T | non_coding_transcript_exon_variant | 0.67 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472123 | n.278A>T | non_coding_transcript_exon_variant | 0.83 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472124 | n.279C>T | non_coding_transcript_exon_variant | 0.84 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.93 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472151 | n.306C>A | non_coding_transcript_exon_variant | 0.25 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472155 | n.310C>T | non_coding_transcript_exon_variant | 0.88 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472160 | n.315C>T | non_coding_transcript_exon_variant | 0.71 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472172 | n.327T>C | non_coding_transcript_exon_variant | 0.29 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472225 | n.380C>A | non_coding_transcript_exon_variant | 0.76 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Uncertain significance | |||||
rrs | 1472251 | n.406G>A | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472258 | n.413A>G | non_coding_transcript_exon_variant | 0.86 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472259 | n.414C>A | non_coding_transcript_exon_variant | 0.87 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472544 | n.699C>A | non_coding_transcript_exon_variant | 0.57 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472545 | n.700A>T | non_coding_transcript_exon_variant | 0.57 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472549 | n.704G>A | non_coding_transcript_exon_variant | 0.33 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472566 | n.721G>A | non_coding_transcript_exon_variant | 0.54 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472571 | n.726G>C | non_coding_transcript_exon_variant | 0.59 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472579 | n.734G>T | non_coding_transcript_exon_variant | 0.42 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472581 | n.736A>C | non_coding_transcript_exon_variant | 0.43 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472581 | n.736A>T | non_coding_transcript_exon_variant | 0.55 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472584 | n.739A>T | non_coding_transcript_exon_variant | 0.43 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472598 | n.753A>C | non_coding_transcript_exon_variant | 0.49 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472599 | n.754G>T | non_coding_transcript_exon_variant | 0.49 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472616 | n.771G>A | non_coding_transcript_exon_variant | 0.39 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472697 | n.852T>C | non_coding_transcript_exon_variant | 0.47 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472713 | n.868T>C | non_coding_transcript_exon_variant | 0.5 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472714 | n.869A>G | non_coding_transcript_exon_variant | 0.43 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472716 | n.871C>T | non_coding_transcript_exon_variant | 0.48 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472742 | n.897C>T | non_coding_transcript_exon_variant | 0.52 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472744 | n.899A>G | non_coding_transcript_exon_variant | 0.52 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472781 | n.936C>T | non_coding_transcript_exon_variant | 0.5 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472790 | n.945T>C | non_coding_transcript_exon_variant | 0.5 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472793 | n.948A>T | non_coding_transcript_exon_variant | 0.48 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472803 | n.958T>A | non_coding_transcript_exon_variant | 0.5 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472824 | n.979T>A | non_coding_transcript_exon_variant | 0.94 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472895 | n.1050C>T | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472954 | n.1109T>C | non_coding_transcript_exon_variant | 0.66 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472956 | n.1111T>C | non_coding_transcript_exon_variant | 0.96 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472957 | n.1112C>T | non_coding_transcript_exon_variant | 0.69 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472958 | n.1113A>G | non_coding_transcript_exon_variant | 0.29 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472973 | n.1128A>G | non_coding_transcript_exon_variant | 0.7 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472973 | n.1128A>T | non_coding_transcript_exon_variant | 0.28 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472974 | n.1129A>G | non_coding_transcript_exon_variant | 0.29 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472988 | n.1143T>C | non_coding_transcript_exon_variant | 0.3 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472990 | n.1145A>G | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
kanamycin | Not assoc w R | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1472992 | n.1147A>G | non_coding_transcript_exon_variant | 0.67 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473005 | n.1160C>T | non_coding_transcript_exon_variant | 0.71 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473035 | n.1190G>A | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473055 | n.1210C>T | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473056 | n.1211A>T | non_coding_transcript_exon_variant | 0.97 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473066 | n.1221A>G | non_coding_transcript_exon_variant | 0.98 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473080 | n.1235C>T | non_coding_transcript_exon_variant | 0.56 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473081 | n.1236C>T | non_coding_transcript_exon_variant | 0.56 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473088 | n.1243A>G | non_coding_transcript_exon_variant | 0.94 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473093 | n.1248C>T | non_coding_transcript_exon_variant | 0.51 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473100 | n.1255G>A | non_coding_transcript_exon_variant | 0.89 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473102 | n.1257C>T | non_coding_transcript_exon_variant | 0.27 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.93 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 0.93 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.93 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473121 | n.1276T>C | non_coding_transcript_exon_variant | 0.88 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1473123 | n.1278A>T | non_coding_transcript_exon_variant | 0.94 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473130 | n.1285G>A | non_coding_transcript_exon_variant | 0.47 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.6 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473148 | n.1303G>T | non_coding_transcript_exon_variant | 0.33 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473163 | n.1318C>A | non_coding_transcript_exon_variant | 0.28 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.7 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473172 | n.1327T>G | non_coding_transcript_exon_variant | 0.64 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473173 | n.1328C>T | non_coding_transcript_exon_variant | 0.92 | streptomycin | Not assoc w R |
kanamycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1473221 | n.1376C>T | non_coding_transcript_exon_variant | 0.93 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473252 | n.1407T>C | non_coding_transcript_exon_variant | 0.8 | streptomycin | Uncertain significance |
kanamycin | Not assoc w R | |||||
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1473259 | n.1414C>T | non_coding_transcript_exon_variant | 0.81 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473276 | n.1431A>C | non_coding_transcript_exon_variant | 0.91 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473277 | n.1432G>A | non_coding_transcript_exon_variant | 0.82 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473288 | n.1443_1449delCTCGGGAinsGGCTTGTCCGGG | non_coding_transcript_exon_variant | 0.92 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473300 | n.1455C>T | non_coding_transcript_exon_variant | 0.73 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473301 | n.1456T>G | non_coding_transcript_exon_variant | 0.82 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473316 | n.1471C>T | non_coding_transcript_exon_variant | 0.84 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473822 | n.165delAinsTG | non_coding_transcript_exon_variant | 0.5 | capreomycin | |
linezolid | ||||||
rrl | 1474181 | n.524C>A | non_coding_transcript_exon_variant | 0.86 | capreomycin | |
linezolid | ||||||
rrl | 1474184 | n.527C>T | non_coding_transcript_exon_variant | 0.91 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474197 | n.540C>T | non_coding_transcript_exon_variant | 0.92 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474199 | n.542G>C | non_coding_transcript_exon_variant | 0.84 | capreomycin | |
linezolid | ||||||
rrl | 1474200 | n.545delT | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474387 | n.730C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474393 | n.736A>G | non_coding_transcript_exon_variant | 0.9 | capreomycin | |
linezolid | ||||||
rrl | 1474448 | n.791T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474467 | n.810A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474488 | n.831G>T | non_coding_transcript_exon_variant | 0.85 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474495 | n.838G>A | non_coding_transcript_exon_variant | 0.82 | capreomycin | |
linezolid | ||||||
rrl | 1474498 | n.841G>T | non_coding_transcript_exon_variant | 0.81 | capreomycin | |
linezolid | ||||||
rrl | 1474505 | n.848C>G | non_coding_transcript_exon_variant | 0.8 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474508 | n.851C>T | non_coding_transcript_exon_variant | 0.81 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474516 | n.859C>A | non_coding_transcript_exon_variant | 0.79 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474527 | n.870T>C | non_coding_transcript_exon_variant | 0.83 | capreomycin | |
linezolid | ||||||
rrl | 1474537 | n.880G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474540 | n.883T>C | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1474542 | n.885A>G | non_coding_transcript_exon_variant | 0.79 | capreomycin | |
linezolid | ||||||
rrl | 1474545 | n.888G>A | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1474626 | n.969T>C | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474634 | n.977T>G | non_coding_transcript_exon_variant | 0.88 | capreomycin | |
linezolid | ||||||
rrl | 1474636 | n.979A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474638 | n.981C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474658 | n.1001A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474663 | n.1006C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474673 | n.1016T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474692 | n.1035G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474753 | n.1096_1097delACinsG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474824 | n.1167A>G | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474831 | n.1174A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474864 | n.1207C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1475751 | n.2094C>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1475754 | n.2097G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1475756 | n.2099T>C | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
linezolid | ||||||
rrl | 1475760 | n.2103_2107delCCGCAinsACCCCCCG | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2108A>G | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475767 | n.2110_2111insT | non_coding_transcript_exon_variant | 0.64 | capreomycin | |
linezolid | ||||||
rrl | 1475774 | n.2117C>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475777 | n.2120A>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1475883 | n.2226A>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475884 | n.2227A>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475898 | n.2241A>G | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475899 | n.2242G>A | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475900 | n.2243A>G | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476359 | n.2702C>G | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476381 | n.2724G>C | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.7 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476429 | n.2772A>T | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476466 | n.2809C>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476481 | n.2824T>C | non_coding_transcript_exon_variant | 0.53 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476506 | n.2849T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476513 | n.2856G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.83 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476585 | n.2928A>G | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476600 | n.2943A>C | non_coding_transcript_exon_variant | 0.68 | capreomycin | |
linezolid | ||||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476614 | n.2957A>T | non_coding_transcript_exon_variant | 0.85 | capreomycin | |
linezolid | ||||||
rrl | 1476616 | n.2959A>G | non_coding_transcript_exon_variant | 0.75 | capreomycin | |
linezolid | ||||||
rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 0.75 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>G | non_coding_transcript_exon_variant | 0.65 | capreomycin | |
linezolid | ||||||
rrl | 1476629 | n.2972C>A | non_coding_transcript_exon_variant | 0.75 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476633 | n.2976A>G | non_coding_transcript_exon_variant | 0.74 | capreomycin | |
linezolid | ||||||
fabG1 | 1673941 | p.Ala168Ser | missense_variant | 0.56 | ethionamide | |
isoniazid | ||||||
inhA | 1673955 | c.-247G>C | upstream_gene_variant | 0.56 | ethionamide | |
isoniazid | ||||||
inhA | 1673961 | c.-241A>C | upstream_gene_variant | 0.5 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673962 | p.Asn175Gly | missense_variant | 0.5 | ethionamide | |
isoniazid | ||||||
inhA | 1673985 | c.-217C>G | upstream_gene_variant | 0.48 | ethionamide | |
isoniazid | ||||||
fabG1 | 1674006 | p.Asp189Glu | missense_variant | 0.54 | ethionamide | |
isoniazid | ||||||
inhA | 1674012 | c.-190C>T | upstream_gene_variant | 0.55 | ethionamide | |
isoniazid | ||||||
inhA | 1674018 | c.-184G>T | upstream_gene_variant | 0.55 | ethionamide | |
isoniazid | ||||||
inhA | 1674504 | c.303C>G | synonymous_variant | 0.69 | ethionamide | |
isoniazid | ||||||
inhA | 1674507 | c.306G>C | synonymous_variant | 0.76 | ethionamide | |
isoniazid | ||||||
inhA | 1674514 | p.Ile105Val | missense_variant | 0.83 | ethionamide | |
isoniazid | ||||||
inhA | 1674537 | c.336C>G | synonymous_variant | 0.81 | ethionamide | |
isoniazid | ||||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 0.81 | ethionamide | |
isoniazid | ||||||
inhA | 1674546 | c.345T>C | synonymous_variant | 0.74 | ethionamide | |
isoniazid | ||||||
inhA | 1674549 | c.348G>C | synonymous_variant | 0.74 | ethionamide | |
isoniazid | ||||||
inhA | 1674555 | c.354G>A | synonymous_variant | 0.75 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674561 | c.360C>T | synonymous_variant | 0.78 | ethionamide | |
isoniazid | ||||||
inhA | 1674582 | c.381T>C | synonymous_variant | 0.61 | ethionamide | |
isoniazid | ||||||
inhA | 1674585 | c.384T>C | synonymous_variant | 0.59 | ethionamide | |
isoniazid | ||||||
inhA | 1674589 | p.Met130Leu | missense_variant | 0.64 | ethionamide | |
isoniazid | ||||||
inhA | 1674601 | p.Leu134Ala | missense_variant | 0.53 | ethionamide | |
isoniazid | ||||||
inhA | 1674624 | c.423A>C | synonymous_variant | 0.44 | ethionamide | |
isoniazid | ||||||
inhA | 1674636 | c.435C>G | synonymous_variant | 0.45 | ethionamide | |
isoniazid | ||||||
inhA | 1674660 | c.459G>C | synonymous_variant | 0.58 | ethionamide | |
isoniazid | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 0.5 | ethionamide | |
isoniazid | ||||||
inhA | 1674708 | c.507G>A | synonymous_variant | 0.46 | ethionamide | |
isoniazid | ||||||
inhA | 1674718 | c.517A>C | synonymous_variant | 0.4 | ethionamide | |
isoniazid | ||||||
inhA | 1674729 | c.528G>C | synonymous_variant | 0.33 | ethionamide | |
isoniazid | ||||||
inhA | 1674732 | c.531C>T | synonymous_variant | 0.32 | ethionamide | |
isoniazid | ||||||
inhA | 1674795 | c.594G>C | synonymous_variant | 0.65 | ethionamide | |
isoniazid | ||||||
inhA | 1674801 | c.600T>C | synonymous_variant | 0.67 | ethionamide | |
isoniazid | ||||||
inhA | 1674816 | c.615T>G | synonymous_variant | 0.7 | ethionamide | |
isoniazid | ||||||
inhA | 1674846 | p.Ile215Met | missense_variant | 0.58 | ethionamide | |
isoniazid | ||||||
inhA | 1674864 | c.663C>T | synonymous_variant | 0.48 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674870 | c.669T>C | synonymous_variant | 0.46 | ethionamide | |
isoniazid | ||||||
inhA | 1674879 | c.678T>C | synonymous_variant | 0.44 | ethionamide | |
isoniazid | ||||||
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.61 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.63 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.63 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.58 | pyrazinamide | |
rpsA | 1833721 | c.180A>G | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.57 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833748 | c.207C>G | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1833886 | c.345C>G | synonymous_variant | 0.55 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.55 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.55 | pyrazinamide | |
rpsA | 1833971 | c.430C>T | synonymous_variant | 0.52 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.54 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.52 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834081 | c.540C>T | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1834096 | c.555G>C | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1834099 | c.558C>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834105 | c.564C>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834108 | c.567C>G | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834123 | c.582C>G | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834210 | c.669C>T | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834234 | c.693G>C | synonymous_variant | 0.59 | pyrazinamide | |
rpsA | 1834240 | c.699T>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834246 | c.705G>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.65 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.66 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834264 | c.723G>C | synonymous_variant | 0.67 | pyrazinamide | |
rpsA | 1834294 | c.753G>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834298 | p.Gln253Glu | missense_variant | 0.39 | pyrazinamide | |
rpsA | 1834303 | c.762T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.62 | pyrazinamide | |
rpsA | 1834307 | c.766_768delGACinsCG | frameshift_variant&missense_variant | 0.27 | pyrazinamide | Uncertain significance |
rpsA | 1834312 | c.771G>A | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.58 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.63 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.61 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.68 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.65 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.69 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.7 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.64 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.64 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.64 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.58 | pyrazinamide | |
rpsA | 1834513 | c.972C>G | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834540 | c.999G>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834555 | c.1014T>G | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834618 | c.1077G>C | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.55 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.62 | pyrazinamide | |
rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Ser | missense_variant | 0.41 | pyrazinamide | |
rpsA | 1834738 | c.1197A>G | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.52 | pyrazinamide | |
rpsA | 1834765 | p.Glu408Asp | missense_variant | 0.5 | pyrazinamide | |
rpsA | 1834775 | p.Ala412Thr | missense_variant | 0.52 | pyrazinamide | |
rpsA | 1834780 | c.1239A>G | synonymous_variant | 0.52 | pyrazinamide | |
rpsA | 1834786 | c.1245A>G | synonymous_variant | 0.52 | pyrazinamide | |
tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.46 | linezolid | |
tsnR | 1853370 | c.-236_-234delGCAinsTG | upstream_gene_variant | 0.44 | linezolid | |
tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.5 | linezolid | |
tlyA | 1917951 | c.12T>C | synonymous_variant | 0.5 | capreomycin | |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
tlyA | 1917975 | c.36C>G | synonymous_variant | 0.61 | capreomycin | |
tlyA | 1917981 | c.42G>C | synonymous_variant | 0.58 | capreomycin | |
tlyA | 1917990 | c.51G>C | synonymous_variant | 0.48 | capreomycin | |
tlyA | 1917993 | c.54A>G | synonymous_variant | 0.47 | capreomycin | Not assoc w R - Interim |
tlyA | 1917996 | c.57A>G | synonymous_variant | 0.48 | capreomycin | |
tlyA | 1918002 | c.63A>G | synonymous_variant | 0.47 | capreomycin | |
tlyA | 1918036 | p.Arg33Ser | missense_variant | 0.35 | capreomycin | |
bacA | 2064933 | c.-205A>G | upstream_gene_variant | 0.62 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064936 | c.-208C>G | upstream_gene_variant | 0.6 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064942 | c.-214G>A | upstream_gene_variant | 0.59 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064948 | c.-220G>C | upstream_gene_variant | 0.59 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064972 | c.-244T>C | upstream_gene_variant | 0.52 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064978 | c.-250G>C | upstream_gene_variant | 0.52 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064979 | c.-251C>T | upstream_gene_variant | 0.52 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064984 | c.-256A>G | upstream_gene_variant | 0.5 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064993 | c.-265T>C | upstream_gene_variant | 0.46 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
katG | 2155641 | p.Lys157Asn | missense_variant | 0.44 | isoniazid | Uncertain significance |
katG | 2155661 | p.Val151Ile | missense_variant | 0.43 | isoniazid | |
katG | 2155677 | c.435C>G | synonymous_variant | 0.48 | isoniazid | |
katG | 2155680 | c.432G>C | synonymous_variant | 0.48 | isoniazid | |
katG | 2155691 | c.421T>C | synonymous_variant | 0.48 | isoniazid | |
katG | 2155695 | c.417C>G | synonymous_variant | 0.48 | isoniazid | |
katG | 2155704 | c.408C>G | synonymous_variant | 0.52 | isoniazid | |
katG | 2155716 | c.396T>G | synonymous_variant | 0.48 | isoniazid | |
katG | 2155722 | c.390G>C | synonymous_variant | 0.48 | isoniazid | |
katG | 2155728 | c.384G>C | synonymous_variant | 0.43 | isoniazid | |
PPE35 | 2168149 | p.Pro822Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
pncA | 2289925 | c.-684T>C | upstream_gene_variant | 0.7 | pyrazinamide | |
pncA | 2289930 | c.-689A>G | upstream_gene_variant | 0.75 | pyrazinamide | |
pncA | 2289943 | c.-702T>G | upstream_gene_variant | 0.64 | pyrazinamide | |
pncA | 2289948 | c.-707C>T | upstream_gene_variant | 0.6 | pyrazinamide | |
pncA | 2289949 | c.-708A>G | upstream_gene_variant | 0.6 | pyrazinamide | |
pncA | 2289987 | c.-746C>T | upstream_gene_variant | 0.62 | pyrazinamide | |
pncA | 2289991 | c.-750G>C | upstream_gene_variant | 0.62 | pyrazinamide | |
pncA | 2289994 | c.-753A>G | upstream_gene_variant | 0.62 | pyrazinamide | |
pncA | 2289997 | c.-756G>C | upstream_gene_variant | 0.67 | pyrazinamide | |
pncA | 2290009 | c.-768A>G | upstream_gene_variant | 0.59 | pyrazinamide | |
pncA | 2290015 | c.-774A>C | upstream_gene_variant | 0.52 | pyrazinamide | |
pncA | 2290024 | c.-783C>G | upstream_gene_variant | 0.42 | pyrazinamide | |
pncA | 2290030 | c.-791_-789delAATinsCC | upstream_gene_variant | 0.39 | pyrazinamide | |
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.48 | isoniazid | |
kasA | 2517989 | c.-126T>C | upstream_gene_variant | 0.5 | isoniazid | |
kasA | 2517993 | c.-122G>T | upstream_gene_variant | 0.47 | isoniazid | |
kasA | 2518528 | c.414C>G | synonymous_variant | 0.42 | isoniazid | |
kasA | 2518540 | c.426T>C | synonymous_variant | 0.42 | isoniazid | |
kasA | 2518561 | c.447T>C | synonymous_variant | 0.38 | isoniazid | |
kasA | 2518567 | c.453G>C | synonymous_variant | 0.38 | isoniazid | |
kasA | 2518570 | c.456G>C | synonymous_variant | 0.38 | isoniazid | |
kasA | 2518574 | c.460_462delATCinsGG | frameshift_variant&missense_variant | 0.38 | isoniazid | |
kasA | 2518579 | c.465T>C | synonymous_variant | 0.4 | isoniazid | |
kasA | 2518588 | c.474T>C | synonymous_variant | 0.4 | isoniazid | |
kasA | 2518591 | c.477G>C | synonymous_variant | 0.4 | isoniazid | |
kasA | 2518732 | c.618C>G | synonymous_variant | 0.44 | isoniazid | |
kasA | 2518744 | c.630C>T | synonymous_variant | 0.4 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518768 | c.654C>T | synonymous_variant | 0.38 | isoniazid | |
kasA | 2518777 | c.663C>T | synonymous_variant | 0.39 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.37 | isoniazid | |
kasA | 2518789 | c.675G>C | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518792 | c.678C>A | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.37 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.38 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.42 | isoniazid | |
kasA | 2518879 | c.765A>G | synonymous_variant | 0.43 | isoniazid | |
kasA | 2518885 | c.771T>C | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518898 | c.784T>C | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518906 | c.792A>G | synonymous_variant | 0.29 | isoniazid | |
kasA | 2518910 | p.Leu266Met | missense_variant | 0.26 | isoniazid | |
kasA | 2518990 | c.876T>G | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518993 | c.879C>G | synonymous_variant | 0.2 | isoniazid | |
kasA | 2518999 | c.885G>A | synonymous_variant | 0.22 | isoniazid | |
kasA | 2519021 | p.Ala303Lys | missense_variant | 0.23 | isoniazid | |
kasA | 2519050 | c.936C>G | synonymous_variant | 0.38 | isoniazid | |
kasA | 2519053 | c.939G>C | synonymous_variant | 0.39 | isoniazid | |
kasA | 2519062 | c.948T>G | synonymous_variant | 0.53 | isoniazid | |
kasA | 2519068 | c.954C>T | synonymous_variant | 0.5 | isoniazid | |
kasA | 2519107 | c.993T>C | synonymous_variant | 0.48 | isoniazid | |
kasA | 2519108 | c.994_996delGATinsCG | frameshift_variant&missense_variant | 0.48 | isoniazid | |
kasA | 2519116 | c.1002C>G | synonymous_variant | 0.56 | isoniazid | |
kasA | 2519122 | c.1008G>C | synonymous_variant | 0.63 | isoniazid | |
kasA | 2519137 | c.1023T>G | synonymous_variant | 0.64 | isoniazid | |
kasA | 2519158 | c.1044C>T | synonymous_variant | 0.57 | isoniazid | |
kasA | 2519167 | c.1053T>G | synonymous_variant | 0.57 | isoniazid | |
kasA | 2519173 | c.1059C>G | synonymous_variant | 0.6 | isoniazid | |
ahpC | 2726303 | c.111T>C | synonymous_variant | 0.27 | isoniazid | |
ahpC | 2726638 | p.Ala149Val | missense_variant | 0.57 | isoniazid | |
ahpC | 2726645 | c.453C>G | synonymous_variant | 0.6 | isoniazid | |
ahpC | 2726657 | c.465A>C | synonymous_variant | 0.58 | isoniazid | Not assoc w R - Interim |
ahpC | 2726669 | p.Asp159Glu | missense_variant | 0.6 | isoniazid | |
ahpC | 2726672 | c.480G>A | synonymous_variant | 0.6 | isoniazid | Not assoc w R - Interim |
ahpC | 2726675 | c.483A>G | synonymous_variant | 0.6 | isoniazid | |
ahpC | 2726681 | c.489A>C | synonymous_variant | 0.65 | isoniazid | Not assoc w R - Interim |
ahpC | 2726693 | c.501C>G | synonymous_variant | 0.65 | isoniazid | |
ahpC | 2726696 | c.504C>G | synonymous_variant | 0.65 | isoniazid | |
ahpC | 2726717 | c.525A>G | synonymous_variant | 0.67 | isoniazid | |
folC | 2746390 | c.1209G>C | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
folC | 2746393 | c.1206C>G | synonymous_variant | 0.32 | para-aminosalicylic_acid | |
folC | 2746401 | p.Ser400Ala | missense_variant | 0.36 | para-aminosalicylic_acid | |
folC | 2746402 | c.1197T>C | synonymous_variant | 0.35 | para-aminosalicylic_acid | |
folC | 2746414 | c.1183_1185delGAGinsCA | frameshift_variant&missense_variant | 0.35 | para-aminosalicylic_acid | |
folC | 2746420 | c.1179A>G | synonymous_variant | 0.35 | para-aminosalicylic_acid | |
folC | 2746426 | c.1173G>C | synonymous_variant | 0.35 | para-aminosalicylic_acid | |
folC | 2746438 | c.1161G>C | synonymous_variant | 0.31 | para-aminosalicylic_acid | |
folC | 2746478 | p.Phe374Tyr | missense_variant | 0.3 | para-aminosalicylic_acid | |
folC | 2746480 | c.1119A>C | synonymous_variant | 0.3 | para-aminosalicylic_acid | |
Rv2477c | 2782869 | p.Ala392Thr | missense_variant | 0.37 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | ||||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2782876 | c.1167G>C | synonymous_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782882 | c.1161T>C | synonymous_variant | 0.44 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782936 | c.1107G>T | synonymous_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782948 | c.1095A>G | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 0.53 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.5 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.4 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783098 | c.945C>G | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783101 | c.942G>T | synonymous_variant | 0.45 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783149 | c.894G>C | synonymous_variant | 0.55 | ethambutol | |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783158 | c.885A>C | synonymous_variant | 0.58 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783221 | c.822G>C | synonymous_variant | 0.57 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783224 | c.819C>G | synonymous_variant | 0.54 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783230 | c.813T>G | synonymous_variant | 0.54 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783235 | c.808T>C | synonymous_variant | 0.55 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783254 | c.789A>G | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783263 | c.780G>C | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783620 | c.423C>G | synonymous_variant | 0.44 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.48 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783662 | c.381G>A | synonymous_variant | 0.54 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.52 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.48 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783718 | c.325T>C | synonymous_variant | 0.53 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 0.53 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.36 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.36 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783766 | p.Met93Leu | missense_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783776 | c.267G>C | synonymous_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783779 | c.264T>C | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783863 | c.180C>T | synonymous_variant | 0.44 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783883 | c.160T>C | synonymous_variant | 0.53 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783884 | c.159T>C | synonymous_variant | 0.53 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783887 | c.156C>G | synonymous_variant | 0.5 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783914 | c.129T>C | synonymous_variant | 0.57 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783920 | c.123G>C | synonymous_variant | 0.54 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783929 | c.114C>G | synonymous_variant | 0.45 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783932 | c.111C>T | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783938 | c.105T>C | synonymous_variant | 0.58 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783953 | c.90G>A | synonymous_variant | 0.59 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783962 | c.81T>C | synonymous_variant | 0.59 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | ||||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783971 | c.72G>C | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783980 | c.63C>G | synonymous_variant | 0.48 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783992 | c.51T>C | synonymous_variant | 0.42 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2680 | 2995848 | c.-257G>A | upstream_gene_variant | 1.0 | capreomycin | |
Rv2681 | 2997287 | c.549G>C | synonymous_variant | 0.19 | capreomycin | |
Rv2752c | 3064809 | c.1383C>G | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064815 | c.1377T>C | synonymous_variant | 0.44 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064831 | p.Ala454Asn | missense_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064838 | c.1354T>C | synonymous_variant | 0.47 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065087 | c.1105A>C | synonymous_variant | 0.45 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | Not assoc w R - Interim | |||||
Rv2752c | 3065088 | c.1104A>G | synonymous_variant | 0.48 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
Rv2752c | 3065109 | c.1081_1083delAGAinsCC | frameshift_variant&missense_variant | 0.4 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv2752c | 3065115 | c.1077C>A | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065142 | c.1050A>C | synonymous_variant | 0.38 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
Rv2752c | 3065146 | p.Phe349Tyr | missense_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065151 | c.1041G>C | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066102 | c.90C>T | synonymous_variant | 0.36 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066118 | p.Asn25Ser | missense_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066531 | c.-340C>G | upstream_gene_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066549 | c.-358T>C | upstream_gene_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066561 | c.-370A>C | upstream_gene_variant | 0.43 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066567 | c.-376C>G | upstream_gene_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066573 | c.-382G>C | upstream_gene_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066579 | c.-388A>G | upstream_gene_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066582 | c.-392_-391delCCinsGG | upstream_gene_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066774 | c.-583T>C | upstream_gene_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066780 | c.-589C>G | upstream_gene_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066807 | c.-616T>C | upstream_gene_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066810 | c.-619G>A | upstream_gene_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066819 | c.-628T>C | upstream_gene_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066822 | c.-631T>C | upstream_gene_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066839 | c.-648A>G | upstream_gene_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066855 | c.-664T>C | upstream_gene_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
thyX | 3067325 | c.621A>G | synonymous_variant | 0.41 | para-aminosalicylic_acid | |
thyX | 3067349 | c.597G>C | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyX | 3067355 | c.591A>C | synonymous_variant | 0.36 | para-aminosalicylic_acid | |
thyX | 3067367 | c.579G>C | synonymous_variant | 0.35 | para-aminosalicylic_acid | |
thyX | 3067373 | c.573C>G | synonymous_variant | 0.36 | para-aminosalicylic_acid | |
thyX | 3067376 | c.570G>A | synonymous_variant | 0.36 | para-aminosalicylic_acid | |
thyX | 3067391 | c.555G>C | synonymous_variant | 0.4 | para-aminosalicylic_acid | |
thyX | 3067394 | c.552G>C | synonymous_variant | 0.43 | para-aminosalicylic_acid | |
thyX | 3067439 | c.507A>G | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyX | 3067445 | c.501C>G | synonymous_variant | 0.4 | para-aminosalicylic_acid | |
thyX | 3067457 | c.489C>G | synonymous_variant | 0.33 | para-aminosalicylic_acid | |
thyX | 3067465 | p.Ile161Val | missense_variant | 0.39 | para-aminosalicylic_acid | |
thyX | 3067475 | c.471A>G | synonymous_variant | 0.5 | para-aminosalicylic_acid | |
thyX | 3067490 | c.456C>G | synonymous_variant | 0.49 | para-aminosalicylic_acid | |
thyX | 3067493 | c.453A>G | synonymous_variant | 0.49 | para-aminosalicylic_acid | |
thyX | 3067515 | p.Ser144Thr | missense_variant | 0.48 | para-aminosalicylic_acid | |
thyX | 3067530 | p.Ala139Ser | missense_variant | 0.36 | para-aminosalicylic_acid | |
thyX | 3067545 | p.Glu134Ala | missense_variant | 0.34 | para-aminosalicylic_acid | |
thyX | 3067549 | p.Thr133Ala | missense_variant | 0.3 | para-aminosalicylic_acid | |
thyX | 3067556 | p.His130Gln | missense_variant | 0.29 | para-aminosalicylic_acid | |
thyX | 3067559 | c.387C>G | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
thyX | 3067565 | p.Asp127Glu | missense_variant | 0.28 | para-aminosalicylic_acid | |
thyX | 3067583 | c.363C>G | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067601 | p.Arg115His | missense_variant | 0.31 | para-aminosalicylic_acid | |
thyX | 3067611 | p.Lys112Thr | missense_variant | 0.3 | para-aminosalicylic_acid | |
thyX | 3067619 | c.327A>C | synonymous_variant | 0.33 | para-aminosalicylic_acid | |
thyX | 3067631 | c.315C>G | synonymous_variant | 0.32 | para-aminosalicylic_acid | |
thyX | 3067634 | c.312C>G | synonymous_variant | 0.32 | para-aminosalicylic_acid | |
thyX | 3067652 | c.294T>C | synonymous_variant | 0.43 | para-aminosalicylic_acid | |
thyX | 3067661 | c.285C>G | synonymous_variant | 0.46 | para-aminosalicylic_acid | |
thyX | 3067718 | c.228C>G | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyX | 3067721 | c.225T>C | synonymous_variant | 0.37 | para-aminosalicylic_acid | |
thyX | 3067727 | c.219A>C | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyX | 3067761 | p.Arg62Lys | missense_variant | 0.32 | para-aminosalicylic_acid | |
thyX | 3067765 | p.Leu61Ile | missense_variant | 0.3 | para-aminosalicylic_acid | |
thyX | 3067772 | c.174C>G | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyX | 3067781 | c.165C>A | synonymous_variant | 0.39 | para-aminosalicylic_acid | |
thyX | 3067793 | c.153T>C | synonymous_variant | 0.47 | para-aminosalicylic_acid | |
thyX | 3067799 | c.147G>A | synonymous_variant | 0.44 | para-aminosalicylic_acid | |
thyX | 3067802 | c.144C>G | synonymous_variant | 0.43 | para-aminosalicylic_acid | |
thyX | 3067814 | c.132T>C | synonymous_variant | 0.46 | para-aminosalicylic_acid | |
thyX | 3067850 | c.96A>C | synonymous_variant | 0.39 | para-aminosalicylic_acid | |
thyX | 3067869 | p.Thr26Ser | missense_variant | 0.38 | para-aminosalicylic_acid | |
thyX | 3067874 | c.72C>G | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyA | 3073815 | c.657G>A | synonymous_variant | 0.4 | para-aminosalicylic_acid | |
thyA | 3073824 | c.648A>G | synonymous_variant | 0.39 | para-aminosalicylic_acid | |
thyA | 3073827 | c.645A>G | synonymous_variant | 0.42 | para-aminosalicylic_acid | |
thyA | 3073836 | c.636C>T | synonymous_variant | 0.46 | para-aminosalicylic_acid | |
thyA | 3073839 | c.633T>C | synonymous_variant | 0.46 | para-aminosalicylic_acid | |
thyA | 3073860 | c.612C>G | synonymous_variant | 0.56 | para-aminosalicylic_acid | |
thyA | 3073863 | c.609T>C | synonymous_variant | 0.54 | para-aminosalicylic_acid | |
thyA | 3073866 | c.606C>G | synonymous_variant | 0.52 | para-aminosalicylic_acid | |
thyA | 3073872 | c.598_600delATCinsGG | frameshift_variant&missense_variant | 0.54 | para-aminosalicylic_acid | |
thyA | 3073892 | c.580T>C | synonymous_variant | 0.55 | para-aminosalicylic_acid | |
thyA | 3073898 | p.Ala192Ser | missense_variant | 0.58 | para-aminosalicylic_acid | |
thyA | 3073917 | c.555C>G | synonymous_variant | 0.54 | para-aminosalicylic_acid | |
thyA | 3073920 | c.552C>G | synonymous_variant | 0.59 | para-aminosalicylic_acid | |
thyA | 3073925 | c.547T>C | synonymous_variant | 0.62 | para-aminosalicylic_acid | |
thyA | 3073929 | c.543T>C | synonymous_variant | 0.64 | para-aminosalicylic_acid | |
thyA | 3073953 | c.519T>C | synonymous_variant | 0.62 | para-aminosalicylic_acid | |
thyA | 3073956 | c.516G>C | synonymous_variant | 0.6 | para-aminosalicylic_acid | |
thyA | 3073959 | c.513T>C | synonymous_variant | 0.64 | para-aminosalicylic_acid | |
thyA | 3073977 | c.495A>G | synonymous_variant | 0.62 | para-aminosalicylic_acid | |
thyA | 3073989 | c.483T>C | synonymous_variant | 0.6 | para-aminosalicylic_acid | |
thyA | 3074154 | c.318T>C | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyA | 3074157 | c.315C>G | synonymous_variant | 0.35 | para-aminosalicylic_acid | |
thyA | 3074160 | c.312A>G | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyA | 3074163 | c.307_309delGCTinsAG | frameshift_variant&missense_variant | 0.43 | para-aminosalicylic_acid | |
thyA | 3074172 | c.300G>C | synonymous_variant | 0.46 | para-aminosalicylic_acid | |
thyA | 3074175 | c.297A>G | synonymous_variant | 0.47 | para-aminosalicylic_acid | |
thyA | 3074181 | c.291A>G | synonymous_variant | 0.47 | para-aminosalicylic_acid | |
thyA | 3074187 | c.285T>C | synonymous_variant | 0.47 | para-aminosalicylic_acid | |
thyA | 3074205 | p.Glu89Asp | missense_variant | 0.53 | para-aminosalicylic_acid | |
thyA | 3074214 | c.258T>C | synonymous_variant | 0.41 | para-aminosalicylic_acid | |
ald | 3087680 | c.861G>C | synonymous_variant | 0.29 | cycloserine | |
ald | 3087704 | c.885T>C | synonymous_variant | 0.31 | cycloserine | |
ald | 3087716 | c.897G>C | synonymous_variant | 0.35 | cycloserine | |
Rv3083 | 3448507 | c.5_*1408del | frameshift_variant&stop_lost&splice_region_variant | 1.0 | ethionamide | Uncertain significance |
Rv3236c | 3613636 | c.-520A>G | upstream_gene_variant | 1.0 | pyrazinamide | Not assoc w R |
lpqB | 3623703 | p.Ala403Val | missense_variant | 0.3 | bedaquiline | |
rifampicin | ||||||
lpqB | 3623705 | c.1206C>T | synonymous_variant | 0.3 | bedaquiline | |
rifampicin | ||||||
lpqB | 3623721 | p.Ser397Thr | missense_variant | 0.4 | bedaquiline | |
rifampicin | ||||||
lpqB | 3623766 | p.Gly382Ala | missense_variant | 0.37 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624077 | c.834G>A | synonymous_variant | 0.47 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624082 | c.829A>C | synonymous_variant | 0.45 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624086 | c.825C>T | synonymous_variant | 0.45 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624092 | c.817_819delAGGinsCC | frameshift_variant&missense_variant | 0.45 | bedaquiline | |
rifampicin | Uncertain significance | |||||
lpqB | 3624100 | c.811T>C | synonymous_variant | 0.47 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624101 | c.810C>G | synonymous_variant | 0.47 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624107 | c.804C>T | synonymous_variant | 0.38 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624116 | c.795A>G | synonymous_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624119 | c.792C>G | synonymous_variant | 0.39 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624124 | p.Leu263Val | missense_variant | 0.39 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624125 | c.786A>G | synonymous_variant | 0.41 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624143 | c.768T>C | synonymous_variant | 0.46 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624701 | c.210T>C | synonymous_variant | 0.36 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624704 | c.207G>C | synonymous_variant | 0.39 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624707 | c.204G>C | synonymous_variant | 0.39 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624722 | c.189C>G | synonymous_variant | 0.43 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624728 | c.183C>T | synonymous_variant | 0.46 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624749 | c.162G>A | synonymous_variant | 0.47 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624755 | c.154_156delTTAinsCG | frameshift_variant&missense_variant | 0.47 | bedaquiline | |
rifampicin | Uncertain significance | |||||
lpqB | 3624770 | c.141T>C | synonymous_variant | 0.47 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624776 | c.135T>C | synonymous_variant | 0.47 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624783 | p.Ser43Thr | missense_variant | 0.44 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625222 | c.1392T>C | synonymous_variant | 0.42 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625225 | c.-315G>C | upstream_gene_variant | 0.42 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625240 | c.-330T>C | upstream_gene_variant | 0.44 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625243 | c.-333T>G | upstream_gene_variant | 0.44 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625513 | c.-603G>C | upstream_gene_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625518 | c.-608T>C | upstream_gene_variant | 0.45 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625525 | c.-615G>C | upstream_gene_variant | 0.48 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625528 | c.-618G>T | upstream_gene_variant | 0.48 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625537 | c.-627T>C | upstream_gene_variant | 0.5 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 0.56 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625549 | c.-639G>A | upstream_gene_variant | 0.58 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625569 | c.1045T>C | synonymous_variant | 0.67 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625572 | p.Thr348Ser | missense_variant | 0.69 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 0.68 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 0.68 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.68 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 0.67 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625616 | p.Arg333Ala | missense_variant | 0.62 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 0.64 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625636 | c.978C>G | synonymous_variant | 0.63 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625656 | c.958T>C | synonymous_variant | 0.55 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.53 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 0.5 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.46 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.46 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 0.54 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625705 | c.909C>G | synonymous_variant | 0.5 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 0.52 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625720 | c.894G>C | synonymous_variant | 0.5 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625729 | c.885A>G | synonymous_variant | 0.58 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 0.63 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625749 | c.-839C>T | upstream_gene_variant | 0.63 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625750 | c.864G>A | synonymous_variant | 0.63 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.67 | bedaquiline | |
rifampicin | Uncertain significance | |||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 0.64 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625774 | c.840G>A | synonymous_variant | 0.72 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625797 | p.Val273Met | missense_variant | 0.71 | bedaquiline | Uncertain significance |
rifampicin | Uncertain significance | |||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.69 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625807 | c.807C>G | synonymous_variant | 0.67 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625837 | c.777C>G | synonymous_variant | 0.5 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 0.41 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625852 | c.762A>G | synonymous_variant | 0.45 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 0.43 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 0.33 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3626774 | c.574_576delAGGinsCC | frameshift_variant&missense_variant | 0.33 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 0.5 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 0.5 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 0.5 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627065 | c.-452G>C | upstream_gene_variant | 0.5 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 0.47 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3627071 | c.279G>T | synonymous_variant | 0.5 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627074 | c.-461G>C | upstream_gene_variant | 0.47 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627080 | c.270T>C | synonymous_variant | 0.5 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 0.5 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627098 | c.252A>C | synonymous_variant | 0.5 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.5 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627119 | c.231T>G | synonymous_variant | 0.41 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.41 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627227 | c.123T>C | synonymous_variant | 0.35 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3627242 | c.108C>T | synonymous_variant | 0.39 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.32 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 0.36 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627275 | c.-662G>T | upstream_gene_variant | 0.35 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 0.35 | bedaquiline | |
rifampicin | ||||||
rpoA | 3877553 | p.Glu319Gln | missense_variant | 0.47 | rifampicin | |
rpoA | 3877571 | p.Pro313Ala | missense_variant | 0.47 | rifampicin | |
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.42 | rifampicin | |
rpoA | 3877656 | c.852T>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoA | 3877668 | c.840A>G | synonymous_variant | 0.57 | rifampicin | |
rpoA | 3877679 | p.Ala277Ser | missense_variant | 0.61 | rifampicin | |
rpoA | 3877686 | c.822A>G | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>C | synonymous_variant | 0.5 | rifampicin | |
rpoA | 3877743 | c.765T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoA | 3877791 | c.717C>G | synonymous_variant | 0.45 | rifampicin | |
rpoA | 3877818 | c.690A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoA | 3877848 | c.660C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoA | 3877857 | c.651G>A | synonymous_variant | 0.36 | rifampicin | |
rpoA | 3877866 | c.642G>C | synonymous_variant | 0.39 | rifampicin | |
rpoA | 3877875 | c.633T>G | synonymous_variant | 0.36 | rifampicin | |
rpoA | 3877878 | c.630G>C | synonymous_variant | 0.36 | rifampicin | |
rpoA | 3877890 | c.618C>T | synonymous_variant | 0.42 | rifampicin | |
rpoA | 3877896 | c.612G>C | synonymous_variant | 0.38 | rifampicin | |
rpoA | 3877900 | p.Ser203Asn | missense_variant | 0.41 | rifampicin | |
rpoA | 3877905 | c.603A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoA | 3877909 | p.Asn200Ser | missense_variant | 0.39 | rifampicin | |
rpoA | 3877920 | c.588G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoA | 3877923 | c.585C>T | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoA | 3877926 | c.582G>C | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3877962 | c.546G>T | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoA | 3877986 | c.522G>C | synonymous_variant | 0.34 | rifampicin | |
rpoA | 3877989 | c.519A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878001 | c.507A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoA | 3878022 | c.486T>C | synonymous_variant | 0.33 | rifampicin | |
rpoA | 3878130 | c.378C>G | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878141 | p.Met123Leu | missense_variant | 0.33 | rifampicin | Uncertain significance |
rpoA | 3878143 | p.Gly122Asp | missense_variant | 0.33 | rifampicin | Uncertain significance |
rpoA | 3878157 | c.351C>G | synonymous_variant | 0.4 | rifampicin | |
rpoA | 3878163 | c.345C>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoA | 3878226 | c.282C>G | synonymous_variant | 0.33 | rifampicin | |
rpoA | 3878232 | c.276G>C | synonymous_variant | 0.36 | rifampicin | |
rpoA | 3878247 | c.261G>C | synonymous_variant | 0.38 | rifampicin | |
rpoA | 3878271 | c.237T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoA | 3878284 | p.Glu75Ala | missense_variant | 0.36 | rifampicin | |
rpoA | 3878292 | c.216T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoA | 3878298 | c.210A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoA | 3878304 | c.204G>C | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoA | 3878322 | c.186A>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoA | 3878331 | c.177A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoA | 3878334 | c.174T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoA | 3878340 | c.168C>T | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878346 | c.162T>C | synonymous_variant | 0.35 | rifampicin | |
rpoA | 3878713 | c.-206G>A | upstream_gene_variant | 0.69 | rifampicin | Uncertain significance |
rpoA | 3878716 | c.-209C>G | upstream_gene_variant | 0.69 | rifampicin | |
rpoA | 3878725 | c.-218A>G | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3878736 | c.-229A>G | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3878737 | c.-230G>C | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 0.71 | rifampicin | Uncertain significance |
rpoA | 3878749 | c.-242G>T | upstream_gene_variant | 0.71 | rifampicin | |
rpoA | 3878761 | c.-254G>C | upstream_gene_variant | 0.8 | rifampicin | |
rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 0.77 | rifampicin | |
rpoA | 3878785 | c.-278T>G | upstream_gene_variant | 0.64 | rifampicin | |
rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.6 | rifampicin | Uncertain significance |
rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 0.7 | rifampicin | |
rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.67 | rifampicin | Uncertain significance |
rpoA | 3878909 | c.-402A>G | upstream_gene_variant | 0.65 | rifampicin | |
rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 0.65 | rifampicin | Uncertain significance |
rpoA | 3878917 | c.-410G>A | upstream_gene_variant | 0.65 | rifampicin | Uncertain significance |
rpoA | 3878938 | c.-431T>A | upstream_gene_variant | 0.7 | rifampicin | |
rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 0.65 | rifampicin | Uncertain significance |
rpoA | 3878962 | c.-455G>A | upstream_gene_variant | 0.63 | rifampicin | Uncertain significance |
rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 0.56 | rifampicin | Uncertain significance |
rpoA | 3878976 | c.-469A>G | upstream_gene_variant | 0.5 | rifampicin | Uncertain significance |
rpoA | 3878986 | c.-479G>C | upstream_gene_variant | 0.46 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.62 | rifampicin | |
rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 0.74 | rifampicin | |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.75 | rifampicin | |
rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.74 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.66 | rifampicin | |
rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.6 | rifampicin | |
rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.6 | rifampicin | |
rpoA | 3879178 | c.-671T>C | upstream_gene_variant | 0.59 | rifampicin | |
rpoA | 3879190 | c.-683C>G | upstream_gene_variant | 0.48 | rifampicin | |
rpoA | 3879222 | c.-715T>C | upstream_gene_variant | 0.43 | rifampicin | |
rpoA | 3879226 | c.-719G>C | upstream_gene_variant | 0.45 | rifampicin | |
rpoA | 3879229 | c.-722A>G | upstream_gene_variant | 0.45 | rifampicin | |
rpoA | 3879232 | c.-725A>G | upstream_gene_variant | 0.45 | rifampicin | |
clpC1 | 4038293 | c.2412G>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4038302 | c.2403C>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4038356 | c.2349T>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4038359 | c.2346A>G | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4038368 | c.2337T>C | synonymous_variant | 0.46 | pyrazinamide | |
clpC1 | 4038388 | c.2317T>C | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4038392 | c.2313C>T | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4038398 | c.2307G>T | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4038403 | c.2302T>C | synonymous_variant | 0.4 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038407 | c.2298G>C | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4038419 | c.2286T>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4038486 | p.Gly740Asn | missense_variant | 0.37 | pyrazinamide | |
clpC1 | 4038489 | p.Ala739Gly | missense_variant | 0.37 | pyrazinamide | |
clpC1 | 4038494 | c.2211G>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4038497 | p.Ser736Gln | missense_variant | 0.34 | pyrazinamide | |
clpC1 | 4038530 | p.Glu725Asp | missense_variant | 0.43 | pyrazinamide | |
clpC1 | 4038640 | p.Asp689Asn | missense_variant | 0.44 | pyrazinamide | |
clpC1 | 4038653 | c.2052C>T | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4038658 | p.Lys683Gln | missense_variant | 0.44 | pyrazinamide | |
clpC1 | 4038661 | p.Ser682Thr | missense_variant | 0.44 | pyrazinamide | |
clpC1 | 4038662 | c.2043T>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4038671 | c.2034T>C | synonymous_variant | 0.46 | pyrazinamide | |
clpC1 | 4038683 | c.2022T>C | synonymous_variant | 0.43 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038695 | c.2010C>G | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4038707 | c.1998C>G | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4038710 | c.1995G>C | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4038755 | c.1950G>T | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4038770 | c.1935C>T | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4038821 | c.1884G>A | synonymous_variant | 0.59 | pyrazinamide | |
clpC1 | 4038845 | c.1860G>C | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.5 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.52 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4038923 | c.1780_1782delCTAinsTG | frameshift_variant&synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.54 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.55 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.56 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039004 | c.1701C>G | synonymous_variant | 0.65 | pyrazinamide | |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.71 | pyrazinamide | |
clpC1 | 4039064 | c.1641C>T | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.45 | pyrazinamide | |
clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4039183 | c.1522T>C | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039186 | c.1519C>T | synonymous_variant | 0.43 | pyrazinamide | |
clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4039295 | c.1410A>C | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4039319 | c.1386T>C | synonymous_variant | 0.57 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039556 | c.1149G>C | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4039559 | c.1146C>G | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4039562 | c.1143C>G | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4039565 | c.1140G>C | synonymous_variant | 0.67 | pyrazinamide | |
clpC1 | 4039570 | p.Met379Leu | missense_variant | 0.69 | pyrazinamide | Uncertain significance |
clpC1 | 4039576 | p.Ala377Pro | missense_variant | 0.77 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.77 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039589 | c.1116G>C | synonymous_variant | 0.71 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.65 | pyrazinamide | |
clpC1 | 4039622 | c.1083C>T | synonymous_variant | 0.62 | pyrazinamide | |
clpC1 | 4039625 | c.1080G>A | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4039661 | c.1044T>G | synonymous_variant | 0.68 | pyrazinamide | |
clpC1 | 4039664 | c.1041G>C | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.64 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.76 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.69 | pyrazinamide | |
clpC1 | 4039790 | c.915C>G | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039817 | c.888A>C | synonymous_variant | 0.39 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039820 | c.885T>G | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039928 | c.775_777delAGCinsTCG | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039937 | c.768G>C | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4039946 | c.759A>C | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4039979 | c.726C>G | synonymous_variant | 0.54 | pyrazinamide | |
clpC1 | 4039988 | c.717C>G | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.56 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.61 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.59 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.52 | pyrazinamide | |
clpC1 | 4040036 | c.669C>G | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4040093 | c.612C>G | synonymous_variant | 0.39 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.55 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040162 | c.543G>C | synonymous_variant | 0.5 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040165 | c.540G>C | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4040171 | c.534C>G | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4040246 | c.459C>G | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4040249 | c.456A>G | synonymous_variant | 0.5 | pyrazinamide | |
clpC1 | 4040267 | c.438A>G | synonymous_variant | 0.47 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.47 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040277 | c.427_428delTCinsAG | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4040279 | c.426C>G | synonymous_variant | 0.47 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4040318 | c.387C>G | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4040330 | c.375C>G | synonymous_variant | 0.47 | pyrazinamide | |
panD | 4044725 | c.-444C>T | upstream_gene_variant | 0.52 | pyrazinamide | |
panD | 4044737 | c.-456T>C | upstream_gene_variant | 0.61 | pyrazinamide | |
panD | 4044746 | c.-467_-465delGTGinsAC | upstream_gene_variant | 0.61 | pyrazinamide | |
panD | 4044752 | c.-471T>C | upstream_gene_variant | 0.58 | pyrazinamide | |
panD | 4044779 | c.-500_-498delCTAinsTGC | upstream_gene_variant | 0.5 | pyrazinamide | |
panD | 4044788 | c.-507G>C | upstream_gene_variant | 0.5 | pyrazinamide | |
panD | 4044791 | c.-510G>C | upstream_gene_variant | 0.5 | pyrazinamide | |
panD | 4044800 | c.-519C>G | upstream_gene_variant | 0.49 | pyrazinamide | |
panD | 4044812 | c.-531A>C | upstream_gene_variant | 0.38 | pyrazinamide | |
panD | 4044818 | c.-538_-537delCGinsAC | upstream_gene_variant | 0.29 | pyrazinamide | |
panD | 4044823 | c.-542G>C | upstream_gene_variant | 0.29 | pyrazinamide | |
panD | 4044833 | c.-552A>G | upstream_gene_variant | 0.29 | pyrazinamide | |
panD | 4044980 | c.-699A>G | upstream_gene_variant | 0.37 | pyrazinamide | |
panD | 4044983 | c.-702G>T | upstream_gene_variant | 0.4 | pyrazinamide | |
panD | 4044989 | c.-708T>C | upstream_gene_variant | 0.43 | pyrazinamide | |
panD | 4045000 | c.-719A>C | upstream_gene_variant | 0.33 | pyrazinamide | |
panD | 4045001 | c.-720G>C | upstream_gene_variant | 0.35 | pyrazinamide | |
panD | 4045019 | c.-738G>C | upstream_gene_variant | 0.33 | pyrazinamide | |
panD | 4045022 | c.-741C>G | upstream_gene_variant | 0.37 | pyrazinamide | |
panD | 4045028 | c.-747C>G | upstream_gene_variant | 0.4 | pyrazinamide | |
panD | 4045034 | c.-753A>C | upstream_gene_variant | 0.42 | pyrazinamide | |
panD | 4045055 | c.-774T>G | upstream_gene_variant | 0.45 | pyrazinamide | |
panD | 4045067 | c.-786C>G | upstream_gene_variant | 0.42 | pyrazinamide | |
panD | 4045070 | c.-789C>T | upstream_gene_variant | 0.42 | pyrazinamide | |
panD | 4045076 | c.-795A>C | upstream_gene_variant | 0.4 | pyrazinamide | |
panD | 4045088 | c.-807T>C | upstream_gene_variant | 0.35 | pyrazinamide | |
panD | 4045094 | c.-813T>C | upstream_gene_variant | 0.31 | pyrazinamide | |
panD | 4045097 | c.-816T>C | upstream_gene_variant | 0.35 | pyrazinamide | |
panD | 4045105 | c.-824T>C | upstream_gene_variant | 0.37 | pyrazinamide | |
panD | 4045112 | c.-831A>G | upstream_gene_variant | 0.38 | pyrazinamide | |
glpK | 4138643 | c.1113A>C | synonymous_variant | 0.3 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138646 | c.1110G>C | synonymous_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138654 | c.1102C>T | synonymous_variant | 0.32 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4138670 | c.1086G>C | synonymous_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138679 | c.1075_1077delATGinsGC | frameshift_variant&missense_variant | 0.33 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
glpK | 4138695 | p.Pro354Asp | missense_variant | 0.44 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138718 | c.1038T>C | synonymous_variant | 0.53 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138721 | c.1035G>A | synonymous_variant | 0.54 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4138724 | c.1032A>G | synonymous_variant | 0.52 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138730 | c.1026C>G | synonymous_variant | 0.55 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138802 | c.954G>A | synonymous_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138808 | c.948G>T | synonymous_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138817 | c.939T>C | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138822 | p.Asn312Asp | missense_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139143 | c.613T>C | synonymous_variant | 0.37 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139165 | c.591A>G | synonymous_variant | 0.43 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139168 | c.588T>C | synonymous_variant | 0.43 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139177 | c.579T>C | synonymous_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139183 | c.573T>C | synonymous_variant | 0.45 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139186 | c.570G>C | synonymous_variant | 0.45 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | ||||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4139195 | c.561G>T | synonymous_variant | 0.37 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4139198 | c.558C>G | synonymous_variant | 0.37 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | ||||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4139207 | c.549T>C | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139231 | c.525A>C | synonymous_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139581 | p.Asn59Asp | missense_variant | 0.5 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
glpK | 4139588 | c.168G>C | synonymous_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139597 | c.159C>G | synonymous_variant | 0.47 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139601 | p.Arg52Gln | missense_variant | 0.5 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139615 | c.141G>A | synonymous_variant | 0.53 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
embC | 4240780 | c.918T>C | synonymous_variant | 0.52 | ethambutol | |
embC | 4240783 | c.921G>C | synonymous_variant | 0.52 | ethambutol | |
embC | 4240789 | c.927T>C | synonymous_variant | 0.5 | ethambutol | |
embC | 4240819 | c.957A>G | synonymous_variant | 0.37 | ethambutol | |
embC | 4240828 | c.966G>A | synonymous_variant | 0.37 | ethambutol | |
embC | 4240831 | c.969T>G | synonymous_variant | 0.39 | ethambutol | |
embC | 4240867 | c.1005T>C | synonymous_variant | 0.27 | ethambutol | |
embC | 4241023 | c.1161T>G | synonymous_variant | 0.23 | ethambutol | |
embC | 4241032 | c.1170G>C | synonymous_variant | 0.24 | ethambutol | |
embC | 4241038 | c.1176G>C | synonymous_variant | 0.3 | ethambutol | |
embC | 4241047 | c.1185C>G | synonymous_variant | 0.35 | ethambutol | |
embC | 4241050 | c.1188T>G | synonymous_variant | 0.38 | ethambutol | |
embC | 4241053 | c.1191G>C | synonymous_variant | 0.38 | ethambutol | |
embC | 4241089 | c.1227C>G | synonymous_variant | 0.38 | ethambutol | |
embC | 4241095 | c.1233C>T | synonymous_variant | 0.39 | ethambutol | |
embC | 4241107 | c.1245G>C | synonymous_variant | 0.45 | ethambutol | |
embC | 4241140 | c.1278A>G | synonymous_variant | 0.56 | ethambutol | Not assoc w R - Interim |
embC | 4241146 | c.1284C>G | synonymous_variant | 0.54 | ethambutol | |
embC | 4241158 | c.1296T>C | synonymous_variant | 0.55 | ethambutol | |
embC | 4241161 | c.1299C>G | synonymous_variant | 0.5 | ethambutol | Not assoc w R - Interim |
embC | 4241162 | c.1300T>C | synonymous_variant | 0.5 | ethambutol | |
embC | 4241170 | c.1308G>C | synonymous_variant | 0.44 | ethambutol | |
embC | 4241173 | c.1311C>T | synonymous_variant | 0.43 | ethambutol | |
embC | 4241179 | c.1317G>A | synonymous_variant | 0.42 | ethambutol | |
embC | 4241203 | c.1341T>C | synonymous_variant | 0.32 | ethambutol | |
embC | 4241206 | c.1344G>C | synonymous_variant | 0.31 | ethambutol | Not assoc w R - Interim |
embC | 4241218 | c.1356G>C | synonymous_variant | 0.26 | ethambutol | |
embC | 4241394 | p.Lys511Ser | missense_variant | 0.26 | ethambutol | |
embC | 4241449 | c.1587C>G | synonymous_variant | 0.48 | ethambutol | |
embC | 4241453 | p.Ile531Val | missense_variant | 0.39 | ethambutol | |
embC | 4241479 | c.1617C>G | synonymous_variant | 0.39 | ethambutol | |
embC | 4241480 | c.1618T>C | synonymous_variant | 0.37 | ethambutol | |
embC | 4241488 | c.1626G>C | synonymous_variant | 0.36 | ethambutol | |
embC | 4241496 | p.Ala545Gly | missense_variant | 0.37 | ethambutol | |
embC | 4241500 | c.1638A>C | synonymous_variant | 0.35 | ethambutol | |
embC | 4241501 | p.Ser547Thr | missense_variant | 0.35 | ethambutol | |
embC | 4241506 | c.1644G>C | synonymous_variant | 0.35 | ethambutol | |
embC | 4241518 | c.1656A>G | synonymous_variant | 0.43 | ethambutol | |
embC | 4241521 | c.1659T>C | synonymous_variant | 0.46 | ethambutol | Not assoc w R - Interim |
embC | 4241530 | c.1668C>G | synonymous_variant | 0.5 | ethambutol | |
embC | 4241536 | c.1674A>G | synonymous_variant | 0.48 | ethambutol | |
embC | 4241539 | c.1677T>C | synonymous_variant | 0.43 | ethambutol | Not assoc w R - Interim |
embC | 4241545 | c.1683T>C | synonymous_variant | 0.43 | ethambutol | |
embC | 4241548 | c.1686T>C | synonymous_variant | 0.43 | ethambutol | |
embC | 4241551 | c.1689A>G | synonymous_variant | 0.43 | ethambutol | |
embC | 4241567 | p.Ile569Val | missense_variant | 0.5 | ethambutol | |
embC | 4241572 | c.1710C>G | synonymous_variant | 0.52 | ethambutol | |
embC | 4241578 | c.1716G>C | synonymous_variant | 0.48 | ethambutol | |
embC | 4241584 | c.1722T>C | synonymous_variant | 0.54 | ethambutol | |
embC | 4241587 | c.1725C>G | synonymous_variant | 0.56 | ethambutol | |
embC | 4241591 | p.Leu577Val | missense_variant | 0.56 | ethambutol | |
embC | 4242643 | c.2781C>T | synonymous_variant | 0.83 | ethambutol | Not assoc w R |
embA | 4242742 | c.-491C>G | upstream_gene_variant | 0.28 | ethambutol | |
embA | 4242748 | c.-485A>G | upstream_gene_variant | 0.26 | ethambutol | |
embA | 4242754 | c.-479G>C | upstream_gene_variant | 0.24 | ethambutol | |
embC | 4242764 | p.Val968Leu | missense_variant | 0.24 | ethambutol | |
embA | 4242772 | c.-461G>C | upstream_gene_variant | 0.28 | ethambutol | |
embC | 4242779 | p.Asn973Asp | missense_variant | 0.28 | ethambutol | |
embA | 4244690 | c.1458G>A | synonymous_variant | 0.27 | ethambutol | Not assoc w R - Interim |
embA | 4244702 | c.1470C>G | synonymous_variant | 0.29 | ethambutol | |
embA | 4244708 | c.1476C>G | synonymous_variant | 0.27 | ethambutol | |
embA | 4244728 | p.Phe499Trp | missense_variant | 0.32 | ethambutol | |
embA | 4245044 | c.1812G>C | synonymous_variant | 0.36 | ethambutol | |
embA | 4245053 | c.1821G>C | synonymous_variant | 0.44 | ethambutol | |
embA | 4245060 | c.1828T>C | synonymous_variant | 0.5 | ethambutol | |
embA | 4245083 | c.1851A>C | synonymous_variant | 0.51 | ethambutol | |
embA | 4245089 | c.1857G>C | synonymous_variant | 0.54 | ethambutol | |
embA | 4245101 | c.1869G>C | synonymous_variant | 0.62 | ethambutol | |
embA | 4245137 | c.1905T>C | synonymous_variant | 0.63 | ethambutol | |
embA | 4245146 | c.1914G>A | synonymous_variant | 0.61 | ethambutol | |
embA | 4245149 | c.1917C>G | synonymous_variant | 0.6 | ethambutol | |
embA | 4245153 | p.Ile641Val | missense_variant | 0.58 | ethambutol | |
embA | 4245182 | c.1950T>C | synonymous_variant | 0.61 | ethambutol | |
embA | 4245189 | c.1957C>T | synonymous_variant | 0.58 | ethambutol | |
embA | 4245198 | p.Leu656Ile | missense_variant | 0.57 | ethambutol | |
embA | 4245207 | c.1975T>C | synonymous_variant | 0.56 | ethambutol | |
embA | 4245215 | c.1983A>C | synonymous_variant | 0.55 | ethambutol | |
embA | 4245222 | c.1990_1992delTATinsCG | frameshift_variant&missense_variant | 0.42 | ethambutol | Uncertain significance |
embA | 4245248 | c.2016G>C | synonymous_variant | 0.36 | ethambutol | |
embA | 4245257 | c.2025A>G | synonymous_variant | 0.33 | ethambutol | |
embA | 4245263 | c.2031A>G | synonymous_variant | 0.3 | ethambutol | Not assoc w R - Interim |
embB | 4246250 | c.-264G>C | upstream_gene_variant | 0.39 | ethambutol | |
embB | 4246256 | c.-258G>T | upstream_gene_variant | 0.46 | ethambutol | |
embB | 4246259 | c.-255G>C | upstream_gene_variant | 0.46 | ethambutol | |
embA | 4246264 | p.His1011Arg | missense_variant | 0.48 | ethambutol | |
embB | 4246292 | c.-222A>G | upstream_gene_variant | 0.39 | ethambutol | |
embA | 4246305 | p.Ser1025Glu | missense_variant | 0.41 | ethambutol | |
embA | 4246308 | p.Thr1026Ala | missense_variant | 0.41 | ethambutol | |
embB | 4246316 | c.-198T>G | upstream_gene_variant | 0.42 | ethambutol | |
embB | 4246319 | c.-195G>C | upstream_gene_variant | 0.41 | ethambutol | |
embA | 4246329 | p.Thr1033Ala | missense_variant | 0.45 | ethambutol | |
embB | 4246349 | c.-165C>G | upstream_gene_variant | 0.41 | ethambutol | |
embA | 4246359 | c.3127_3129delGCCinsTG | frameshift_variant&missense_variant | 0.32 | ethambutol | Uncertain significance |
embB | 4246367 | c.-147C>T | upstream_gene_variant | 0.25 | ethambutol | |
embB | 4247464 | c.951C>G | synonymous_variant | 0.4 | ethambutol | |
embB | 4247470 | c.957T>C | synonymous_variant | 0.44 | ethambutol | |
embB | 4247491 | c.978G>C | synonymous_variant | 0.52 | ethambutol | |
embB | 4247497 | c.984T>C | synonymous_variant | 0.43 | ethambutol | |
embB | 4247512 | c.999T>C | synonymous_variant | 0.5 | ethambutol | |
embB | 4247539 | c.1026T>C | synonymous_variant | 0.45 | ethambutol | |
embB | 4247554 | c.1041T>C | synonymous_variant | 0.48 | ethambutol | |
embB | 4247566 | c.1053C>A | synonymous_variant | 0.39 | ethambutol | |
embB | 4247819 | c.1306_1308delGTTinsAC | frameshift_variant&missense_variant | 0.29 | ethambutol | |
embB | 4247830 | c.1317A>G | synonymous_variant | 0.28 | ethambutol | Not assoc w R - Interim |
embB | 4247836 | c.1323A>G | synonymous_variant | 0.3 | ethambutol | Not assoc w R - Interim |
embB | 4247839 | c.1326G>C | synonymous_variant | 0.31 | ethambutol | Not assoc w R - Interim |
embB | 4247866 | c.1353G>C | synonymous_variant | 0.28 | ethambutol | |
embB | 4247875 | c.1362G>C | synonymous_variant | 0.26 | ethambutol | |
embB | 4247876 | c.1363C>T | synonymous_variant | 0.27 | ethambutol | |
embB | 4247881 | c.1368G>C | synonymous_variant | 0.32 | ethambutol | |
embB | 4247887 | c.1374C>T | synonymous_variant | 0.31 | ethambutol | Not assoc w R - Interim |
embB | 4247893 | c.1380C>T | synonymous_variant | 0.36 | ethambutol | |
embB | 4247899 | p.Met462Ile | missense_variant | 0.41 | ethambutol | |
embB | 4247905 | c.1392G>C | synonymous_variant | 0.45 | ethambutol | Not assoc w R - Interim |
embB | 4247909 | c.1396T>C | synonymous_variant | 0.45 | ethambutol | |
embB | 4247932 | c.1419C>G | synonymous_variant | 0.44 | ethambutol | |
embB | 4247940 | p.Leu476Trp | missense_variant | 0.36 | ethambutol | |
embB | 4247945 | c.1432T>C | synonymous_variant | 0.33 | ethambutol | |
embB | 4247951 | p.Ser480Ala | missense_variant | 0.38 | ethambutol | |
embB | 4247956 | c.1443G>C | synonymous_variant | 0.39 | ethambutol | Not assoc w R - Interim |
embB | 4247974 | c.1461C>G | synonymous_variant | 0.38 | ethambutol | |
embB | 4248007 | c.1494C>G | synonymous_variant | 0.28 | ethambutol | |
embB | 4248011 | p.Ser500Arg | missense_variant | 0.26 | ethambutol | |
embB | 4248014 | p.Thr501Ala | missense_variant | 0.25 | ethambutol | Uncertain significance |
embB | 4248035 | p.Val508Ile | missense_variant | 0.26 | ethambutol | |
embB | 4248040 | c.1527C>G | synonymous_variant | 0.27 | ethambutol | |
embB | 4248041 | p.Ala510Thr | missense_variant | 0.27 | ethambutol | Uncertain significance |
embB | 4248044 | p.Lys511Ala | missense_variant | 0.27 | ethambutol | |
embB | 4248070 | c.1557T>C | synonymous_variant | 0.38 | ethambutol | |
embB | 4248085 | c.1572T>C | synonymous_variant | 0.41 | ethambutol | |
embB | 4248097 | c.1584C>G | synonymous_variant | 0.54 | ethambutol | |
embB | 4248130 | c.1617G>C | synonymous_variant | 0.54 | ethambutol | |
embB | 4248133 | c.1620C>G | synonymous_variant | 0.56 | ethambutol | |
embB | 4248139 | c.1626C>G | synonymous_variant | 0.54 | ethambutol | |
embB | 4248142 | c.1629T>C | synonymous_variant | 0.48 | ethambutol | |
embB | 4248143 | c.1630T>C | synonymous_variant | 0.48 | ethambutol | |
embB | 4248157 | c.1644A>G | synonymous_variant | 0.58 | ethambutol | Not assoc w R - Interim |
embB | 4248199 | c.1686A>G | synonymous_variant | 0.63 | ethambutol | |
embB | 4248200 | p.Ile563Val | missense_variant | 0.63 | ethambutol | |
embB | 4248205 | c.1692C>G | synonymous_variant | 0.62 | ethambutol | |
embB | 4248206 | c.1693_1695delAGCinsGT | frameshift_variant&missense_variant | 0.62 | ethambutol | |
embB | 4248220 | c.1707A>C | synonymous_variant | 0.68 | ethambutol | |
embB | 4248304 | c.1791G>C | synonymous_variant | 0.5 | ethambutol | |
embB | 4248319 | c.1806A>G | synonymous_variant | 0.45 | ethambutol | |
embB | 4248343 | c.1830G>C | synonymous_variant | 0.44 | ethambutol | |
embB | 4248350 | c.1837T>C | synonymous_variant | 0.38 | ethambutol | |
embB | 4248355 | c.1842A>G | synonymous_variant | 0.42 | ethambutol | |
embB | 4248358 | c.1845C>G | synonymous_variant | 0.39 | ethambutol | |
embB | 4248361 | c.1848A>C | synonymous_variant | 0.44 | ethambutol | |
embB | 4248362 | p.Ser617Ala | missense_variant | 0.47 | ethambutol | |
embB | 4248373 | c.1860C>G | synonymous_variant | 0.53 | ethambutol | |
embB | 4248472 | c.1959T>C | synonymous_variant | 0.32 | ethambutol | |
embB | 4248475 | c.1962G>C | synonymous_variant | 0.3 | ethambutol | |
embB | 4248488 | c.1975_1977delGCGinsAC | frameshift_variant&missense_variant | 0.33 | ethambutol | |
aftB | 4267574 | c.1263G>A | synonymous_variant | 0.41 | ethambutol | |
aftB | 4267580 | c.1257G>T | synonymous_variant | 0.43 | ethambutol | |
aftB | 4267604 | c.1233C>G | synonymous_variant | 0.43 | ethambutol | |
aftB | 4267607 | c.1230G>A | synonymous_variant | 0.43 | ethambutol | |
aftB | 4267622 | c.1215G>C | synonymous_variant | 0.53 | ethambutol | |
aftB | 4267625 | c.1212T>C | synonymous_variant | 0.48 | ethambutol | |
aftB | 4267628 | c.1209C>G | synonymous_variant | 0.5 | ethambutol | |
aftB | 4267634 | p.Arg401His | missense_variant | 0.53 | ethambutol | |
aftB | 4268164 | p.Gln225Glu | missense_variant | 0.32 | ethambutol | |
aftB | 4268169 | p.Ala223Gly | missense_variant | 0.29 | ethambutol | |
aftB | 4268171 | c.666G>C | synonymous_variant | 0.29 | ethambutol | |
aftB | 4268179 | c.658T>C | synonymous_variant | 0.31 | ethambutol | Not assoc w R - Interim |
aftB | 4268985 | c.-149A>G | upstream_gene_variant | 0.24 | ethambutol | |
aftB | 4268994 | c.-158T>G | upstream_gene_variant | 0.26 | ethambutol | |
ubiA | 4268999 | c.835C>T | synonymous_variant | 0.29 | ethambutol | Not assoc w R - Interim |
aftB | 4269006 | c.-170T>C | upstream_gene_variant | 0.35 | ethambutol | |
aftB | 4269012 | c.-176G>C | upstream_gene_variant | 0.39 | ethambutol | |
ubiA | 4269027 | c.807C>T | synonymous_variant | 0.42 | ethambutol | Not assoc w R - Interim |
aftB | 4269033 | c.-197T>C | upstream_gene_variant | 0.42 | ethambutol | |
aftB | 4269036 | c.-200C>G | upstream_gene_variant | 0.42 | ethambutol | |
aftB | 4269042 | c.-206G>C | upstream_gene_variant | 0.41 | ethambutol | |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | capreomycin | Not assoc w R |
amikacin | Not assoc w R | |||||
kanamycin | Not assoc w R |