TB-Profiler result

Run: SRR16278274
Summary

Run ID: SRR16278274

Sample name:

Date: 2025-09-15T16:29:01.304110

Number of reads: 4590361

Percentage reads mapped: 37.89

Median coverage: 87.0

Strain: La1.4

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1 M.bovis None 100.0
La1.4 M.bovis None 100.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide pncA p.His57Asp Assoc w R
streptomycin rrs n.799C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin gyrB p.Ile486Leu Uncertain significance Mutation from literature
ofloxacin
levofloxacin gyrB p.Ile486Leu Uncertain significance Mutation from literature
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
gyrB 6695 p.Ile486Leu missense_variant 0.27 levofloxacin Uncertain significance Mutation from literature
moxifloxacin Uncertain significance Mutation from literature
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance Mutation from literature
pncA 2289073 p.His57Asp missense_variant 1.0 pyrazinamide Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 467 p.His156Arg missense_variant 1.0 isoniazid Not assoc w R
gyrB 5752 c.513G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6172 c.933C>T synonymous_variant 0.97 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6406 c.1167C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6446 p.Ala403Ser missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrA 6700 c.-602T>C upstream_gene_variant 0.3 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6709 c.-593A>G upstream_gene_variant 0.33 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6712 c.-590G>C upstream_gene_variant 0.34 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6718 p.Ile493Met missense_variant 0.34 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6724 c.-578G>C upstream_gene_variant 0.34 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6730 c.-572A>G upstream_gene_variant 0.35 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6733 c.-569G>A upstream_gene_variant 0.33 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6737 p.Thr500Ala missense_variant 0.33 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6742 c.-560A>G upstream_gene_variant 0.33 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6745 c.1506T>C synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.33 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6760 c.-542G>C upstream_gene_variant 0.32 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6775 c.1536G>C synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6779 p.His514Asn missense_variant 0.32 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6784 c.-518C>T upstream_gene_variant 0.32 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6787 c.-515G>A upstream_gene_variant 0.31 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6793 c.1554T>C synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 0.32 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 8285 c.984C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
Rv0010c 13197 p.Thr121Ser missense_variant 1.0 isoniazid Not assoc w R
Rv0010c 13228 c.330delG frameshift_variant 1.0 isoniazid Uncertain significance
Rv0010c 13460 c.99T>C synonymous_variant 1.0 isoniazid Not assoc w R
fgd1 491742 c.960T>C synonymous_variant 0.99 clofazimine Not assoc w R
delamanid Not assoc w R - Interim
pretomanid Uncertain significance
Rv0565c 657578 c.-108T>C upstream_gene_variant 1.0 ethionamide Uncertain significance
nusG 734666 p.Arg138His missense_variant 1.0 rifampicin Uncertain significance
rpoB 760331 c.525G>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoB 760334 c.528G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 760337 c.531C>G synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 760340 c.534G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 760372 c.566_567insGGAG frameshift_variant 0.24 rifampicin Uncertain significance
rpoB 760375 p.Asp190Ala missense_variant 0.23 rifampicin Uncertain significance
rpoB 760376 c.571_574delAAGA frameshift_variant 0.24 rifampicin Uncertain significance
rpoB 760389 c.583_584delAGinsTC synonymous_variant 0.23 rifampicin Uncertain significance
rpoB 760394 c.588C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760400 c.594G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760407 c.601_603delAGCinsTCG synonymous_variant 0.22 rifampicin Uncertain significance
rpoB 760424 c.618C>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 760436 c.630C>G synonymous_variant 0.32 rifampicin Uncertain significance
rpoB 760457 c.651C>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Thr missense_variant 0.16 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.14 rifampicin Uncertain significance
rpoB 760541 c.735G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761990 c.2184G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 761998 c.2193_2195delGTC disruptive_inframe_deletion 0.35 rifampicin Uncertain significance
rpoB 762005 c.2200_2201insAGC disruptive_inframe_insertion 0.34 rifampicin Uncertain significance
rpoB 762009 p.Leu735Val missense_variant 0.35 rifampicin Uncertain significance
rpoB 762017 c.2211A>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 762020 c.2214G>A synonymous_variant 0.35 rifampicin Uncertain significance
rpoB 762024 p.Val740Ile missense_variant 0.34 rifampicin Uncertain significance
rpoB 762035 c.2229G>C synonymous_variant 0.35 rifampicin Uncertain significance
rpoB 762036 p.Ile744Val missense_variant 0.35 rifampicin Uncertain significance
rpoB 762044 c.2238C>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 762050 c.2244G>A synonymous_variant 0.35 rifampicin Uncertain significance
rpoB 762053 c.2247T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762080 c.2274G>C synonymous_variant 0.47 rifampicin Uncertain significance
rpoB 762086 c.2280G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 762104 p.Asp766Glu missense_variant 0.56 rifampicin Uncertain significance
rpoB 762114 p.Ile770Val missense_variant 0.53 rifampicin Uncertain significance
rpoB 762122 p.Asp772Glu missense_variant 0.49 rifampicin Uncertain significance
rpoB 762125 p.Glu773Asp missense_variant 0.47 rifampicin Uncertain significance
rpoB 762132 p.Ala776Lys missense_variant 0.47 rifampicin Uncertain significance
rpoB 762137 c.2331C>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762143 c.2337T>C synonymous_variant 0.52 rifampicin Uncertain significance
rpoB 762149 c.2343G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762156 p.Val784Ile missense_variant 0.54 rifampicin Uncertain significance
rpoB 762167 c.2361T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 762170 c.2364C>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 762173 p.Glu789Asp missense_variant 0.57 rifampicin Uncertain significance
rpoB 762176 c.2370T>G synonymous_variant 0.56 rifampicin Uncertain significance
rpoB 762185 c.2379G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762194 c.2388G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762197 c.2391C>G synonymous_variant 0.58 rifampicin Uncertain significance
rpoB 762218 c.2412T>C synonymous_variant 0.53 rifampicin Uncertain significance
rpoB 762233 c.2427G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 762266 c.2460T>C synonymous_variant 0.32 rifampicin Uncertain significance
rpoB 762284 c.2478G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762296 c.2490G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 762844 p.Phe1013Tyr missense_variant 0.15 rifampicin Uncertain significance
rpoB 762846 p.Pro1014Lys missense_variant 0.15 rifampicin Uncertain significance
rpoB 762855 p.Val1017Ile missense_variant 0.17 rifampicin Uncertain significance
rpoB 762858 p.Thr1018Ser missense_variant 0.16 rifampicin Uncertain significance
rpoB 762863 c.3057T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762878 p.Ile1024Met missense_variant 0.18 rifampicin Uncertain significance
rpoB 762879 p.Met1025Leu missense_variant 0.18 rifampicin Uncertain significance
rpoB 762905 p.Asp1033Glu missense_variant 0.38 rifampicin Uncertain significance
rpoB 762920 c.3114C>T synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 762938 c.-432G>C upstream_gene_variant 0.51 rifampicin Uncertain significance
rpoC 762944 c.-426C>T upstream_gene_variant 0.52 rifampicin Uncertain significance
rpoC 762947 c.-423C>G upstream_gene_variant 0.52 rifampicin Uncertain significance
rpoC 762971 c.-399G>C upstream_gene_variant 0.54 rifampicin Uncertain significance
rpoC 762980 c.-390T>C upstream_gene_variant 0.56 rifampicin Uncertain significance
rpoC 762989 c.-381G>C upstream_gene_variant 0.56 rifampicin Uncertain significance
rpoB 762995 c.3189G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 763005 p.Cys1067Val missense_variant 0.59 rifampicin Uncertain significance
rpoC 763013 c.-357C>G upstream_gene_variant 0.62 rifampicin Uncertain significance
rpoC 763022 c.-348C>A upstream_gene_variant 0.63 rifampicin Uncertain significance
rpoB 763028 c.3222T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 763052 c.-318G>T upstream_gene_variant 0.67 rifampicin Uncertain significance
rpoB 763074 p.Thr1090Val missense_variant 0.59 rifampicin Uncertain significance
rpoC 763079 c.-291C>G upstream_gene_variant 0.58 rifampicin Uncertain significance
rpoB 763088 c.3282C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>C upstream_gene_variant 0.56 rifampicin Uncertain significance
rpoB 763106 c.3300C>T synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763109 c.-261C>G upstream_gene_variant 0.56 rifampicin Uncertain significance
rpoB 763115 c.3309T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 763118 p.Glu1104Asp missense_variant 0.55 rifampicin Uncertain significance
rpoB 763130 p.Glu1108Asp missense_variant 0.54 rifampicin Uncertain significance
rpoC 763139 c.-231C>T upstream_gene_variant 0.51 rifampicin Uncertain significance
rpoC 763142 c.-228C>G upstream_gene_variant 0.49 rifampicin Uncertain significance
rpoC 763148 c.-222G>C upstream_gene_variant 0.46 rifampicin Uncertain significance
rpoB 763166 c.3360A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.37 rifampicin Uncertain significance
rpoC 763178 c.-192G>C upstream_gene_variant 0.28 rifampicin Uncertain significance
rpoC 763185 c.-185_-183delCTCinsTTG upstream_gene_variant 0.16 rifampicin Uncertain significance
rpoC 763453 c.84C>G synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 763456 c.87A>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763462 c.93G>C synonymous_variant 0.33 rifampicin Uncertain significance
rpoC 763468 c.99G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 763471 c.102C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 763483 c.114G>C synonymous_variant 0.38 rifampicin Uncertain significance
rpoC 763486 c.117T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763517 p.Lys50Arg missense_variant 0.39 rifampicin Uncertain significance
rpoC 763528 c.159G>C synonymous_variant 0.42 rifampicin Uncertain significance
rpoC 763534 c.165T>C synonymous_variant 0.42 rifampicin Uncertain significance
rpoC 763546 c.177A>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 763550 p.Tyr61Ala missense_variant 0.42 rifampicin Uncertain significance
rpoC 763570 c.201G>T synonymous_variant 0.48 rifampicin Uncertain significance
rpoC 763573 c.204G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 763578 p.Phe70Tyr missense_variant 0.49 rifampicin Uncertain significance
rpoC 763594 c.225C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763609 c.240C>T synonymous_variant 0.47 rifampicin Uncertain significance
rpoC 763619 p.Arg84Lys missense_variant 0.43 rifampicin Uncertain significance
rpoC 763622 p.Ala85Ser missense_variant 0.41 rifampicin Uncertain significance
rpoC 763633 c.264T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.46 rifampicin Uncertain significance
rpoC 763642 c.273G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>T synonymous_variant 0.4 rifampicin Uncertain significance
rpoC 763669 c.300C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763672 c.303C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>C synonymous_variant 0.36 rifampicin Uncertain significance
rpoC 763702 c.333C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763705 c.336G>C synonymous_variant 0.32 rifampicin Uncertain significance
rpoC 763708 c.339G>C synonymous_variant 0.32 rifampicin Uncertain significance
rpoC 763714 c.345G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.3 rifampicin Uncertain significance
rpoC 763732 c.363C>G synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 763744 c.375G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 764353 c.984G>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 764365 c.996C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764404 c.1035C>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764410 c.1041G>T synonymous_variant 0.43 rifampicin Uncertain significance
rpoC 764428 c.1059G>T synonymous_variant 0.4 rifampicin Uncertain significance
rpoC 764429 c.1060C>T synonymous_variant 0.4 rifampicin Uncertain significance
rpoC 764434 c.1065A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGC synonymous_variant 0.4 rifampicin Uncertain significance
rpoC 764438 p.Leu357Met missense_variant 0.4 rifampicin Uncertain significance
rpoC 764446 c.1077T>C synonymous_variant 0.43 rifampicin Uncertain significance
rpoC 764452 c.1083T>C synonymous_variant 0.41 rifampicin Uncertain significance
rpoC 764458 c.1089G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764470 c.1101C>G synonymous_variant 0.49 rifampicin Uncertain significance
rpoC 764485 c.1116G>C synonymous_variant 0.51 rifampicin Uncertain significance
rpoC 764497 c.1128A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>T synonymous_variant 0.55 rifampicin Uncertain significance
rpoC 764509 c.1140G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>C synonymous_variant 0.56 rifampicin Uncertain significance
rpoC 764556 p.Asn396Thr missense_variant 0.59 rifampicin Uncertain significance
rpoC 764566 c.1197C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764572 c.1203G>C synonymous_variant 0.6 rifampicin Uncertain significance
rpoC 764575 c.1206T>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764581 c.1212T>C synonymous_variant 0.63 rifampicin Uncertain significance
rpoC 764605 c.1236G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>C synonymous_variant 0.69 rifampicin Uncertain significance
rpoC 764623 c.1254C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764635 c.1266C>G synonymous_variant 0.65 rifampicin Uncertain significance
rpoC 764644 c.1275G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764653 c.1284G>C synonymous_variant 0.6 rifampicin Uncertain significance
rpoC 764656 c.1287C>G synonymous_variant 0.6 rifampicin Uncertain significance
rpoC 764659 c.1290C>T synonymous_variant 0.59 rifampicin Uncertain significance
rpoC 764660 p.Val431Ile missense_variant 0.59 rifampicin Uncertain significance
rpoC 764677 c.1308C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764687 p.Gln440Glu missense_variant 0.65 rifampicin Uncertain significance
rpoC 764701 c.1332C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764706 p.Leu446Arg missense_variant 0.64 rifampicin Uncertain significance
rpoC 764716 c.1347G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>C synonymous_variant 0.6 rifampicin Uncertain significance
rpoC 764756 p.Leu463Asn missense_variant 0.54 rifampicin Uncertain significance
rpoC 764759 p.Asn464Asp missense_variant 0.54 rifampicin Uncertain significance
rpoC 764762 p.His465Tyr missense_variant 0.54 rifampicin Uncertain significance
rpoC 764780 c.1411_1412delAGinsTC synonymous_variant 0.58 rifampicin Uncertain significance
rpoC 764797 c.1428G>C synonymous_variant 0.64 rifampicin Uncertain significance
rpoC 764813 p.Gln482Glu missense_variant 0.63 rifampicin Uncertain significance
rpoC 764824 c.1455T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 0.61 rifampicin Uncertain significance
rpoC 764838 p.Val490Ala missense_variant 0.55 rifampicin Uncertain significance
rpoC 764842 c.1473C>T synonymous_variant 0.55 rifampicin Uncertain significance
rpoC 764843 p.Ala492Ser missense_variant 0.55 rifampicin Uncertain significance
rpoC 764858 c.1489T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764863 c.1494G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>G synonymous_variant 0.57 rifampicin Uncertain significance
rpoC 764878 c.1509C>G synonymous_variant 0.57 rifampicin Uncertain significance
rpoC 764887 c.1518G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.52 rifampicin Uncertain significance
rpoC 764913 p.Met515Lys missense_variant 0.51 rifampicin Uncertain significance
rpoC 764920 c.1551G>C synonymous_variant 0.5 rifampicin Uncertain significance
rpoC 764926 c.1557C>T synonymous_variant 0.49 rifampicin Uncertain significance
rpoC 764935 c.1566T>C synonymous_variant 0.45 rifampicin Uncertain significance
rpoC 764948 c.1579T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764952 p.Val528Ala missense_variant 0.28 rifampicin Uncertain significance
rpoC 764968 c.1599T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>A synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 764998 c.1629G>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 766328 p.Lys987Gln missense_variant 0.23 rifampicin Uncertain significance
rpoC 766333 c.2964G>C synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 766345 c.2976T>C synonymous_variant 0.33 rifampicin Uncertain significance
rpoC 766348 c.2979A>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 766369 c.3000C>G synonymous_variant 0.32 rifampicin Uncertain significance
rpoC 766378 c.3009C>T synonymous_variant 0.33 rifampicin Uncertain significance
rpoC 766381 c.3012C>T synonymous_variant 0.34 rifampicin Uncertain significance
rpoC 766384 c.3015A>G synonymous_variant 0.34 rifampicin Uncertain significance
rpoC 766387 c.3018C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 766390 c.3021C>T synonymous_variant 0.34 rifampicin Uncertain significance
rpoC 766393 c.3024C>G synonymous_variant 0.34 rifampicin Uncertain significance
rpoC 766408 c.3039C>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 766423 c.3054T>C synonymous_variant 0.37 rifampicin Uncertain significance
rpoC 766432 c.3063T>C synonymous_variant 0.36 rifampicin Uncertain significance
rpoC 766434 p.Glu1022Gly missense_variant 0.36 rifampicin Uncertain significance
rpoC 766456 c.3087C>G synonymous_variant 0.35 rifampicin Uncertain significance
rpoC 766459 c.3090G>T synonymous_variant 0.35 rifampicin Uncertain significance
rpoC 767002 c.3633G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>C synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 767020 c.3651C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 767023 p.Asp1218Glu missense_variant 0.27 rifampicin Uncertain significance
rpoC 767026 c.3657G>C synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 767041 c.3672G>C synonymous_variant 0.25 rifampicin Uncertain significance
rpoC 767044 c.3675G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 767068 c.3699G>C synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 767071 c.3702C>G synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 767074 c.3705T>C synonymous_variant 0.23 rifampicin Uncertain significance
rpoC 767077 c.3708G>C synonymous_variant 0.23 rifampicin Uncertain significance
rpoC 767087 p.Cys1240Lys missense_variant 0.23 rifampicin Uncertain significance
rpoC 767093 c.3724_3725delAGinsTC synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 767098 c.3729T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 767106 p.Asn1246Ile missense_variant 0.26 rifampicin Uncertain significance
rpoC 767110 c.3741T>C synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 767119 c.3750A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 776100 p.Thr794Ile missense_variant 0.99 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781703 c.144G>T synonymous_variant 0.14 streptomycin Uncertain significance
rpsL 781709 c.150G>T synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781748 c.189C>T synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781749 p.Thr64Ser missense_variant 0.15 streptomycin Uncertain significance
rpsL 781760 c.201T>C synonymous_variant 0.22 streptomycin Uncertain significance
rpsL 781763 c.204C>G synonymous_variant 0.24 streptomycin Uncertain significance
rpsL 781793 c.234G>C synonymous_variant 0.41 streptomycin Uncertain significance
rpsL 781802 c.243G>C synonymous_variant 0.4 streptomycin Uncertain significance
rpsL 781814 c.255C>T synonymous_variant 0.37 streptomycin Uncertain significance
rpsL 781817 c.258G>T synonymous_variant 0.38 streptomycin Uncertain significance
rpsL 781832 c.273T>G synonymous_variant 0.39 streptomycin Uncertain significance
rpsL 781850 c.291C>T synonymous_variant 0.41 streptomycin Uncertain significance
rpsL 781851 p.Ile98Val missense_variant 0.41 streptomycin Uncertain significance
rpsL 781859 c.300T>C synonymous_variant 0.4 streptomycin Not assoc w R - Interim
rpsL 781860 p.Ser101Ala missense_variant 0.41 streptomycin Uncertain significance
rpsL 781871 c.312G>C synonymous_variant 0.42 streptomycin Uncertain significance
rpsL 781880 c.321C>G synonymous_variant 0.42 streptomycin Uncertain significance
rpsL 781884 p.Asn109Asp missense_variant 0.41 streptomycin Uncertain significance
rpsL 781892 c.333A>G synonymous_variant 0.4 streptomycin Uncertain significance
rpsL 781898 c.339A>T synonymous_variant 0.37 streptomycin Uncertain significance
rpsL 781902 c.343_344delAGinsTC synonymous_variant 0.34 streptomycin Uncertain significance
rpsL 781916 c.357T>A synonymous_variant 0.21 streptomycin Uncertain significance
rplC 800516 c.-293G>C upstream_gene_variant 0.13 linezolid Uncertain significance
rplC 800522 c.-287C>T upstream_gene_variant 0.14 linezolid Uncertain significance
rplC 800531 c.-278T>C upstream_gene_variant 0.14 linezolid Uncertain significance
rplC 800537 c.-272C>G upstream_gene_variant 0.14 linezolid Uncertain significance
rplC 800540 c.-269T>C upstream_gene_variant 0.14 linezolid Uncertain significance
rplC 800546 c.-263T>A upstream_gene_variant 0.14 linezolid Uncertain significance
rplC 800549 c.-260G>C upstream_gene_variant 0.15 linezolid Uncertain significance
rplC 800553 c.-256_-254delCGCinsAAG upstream_gene_variant 0.15 linezolid Uncertain significance
rplC 800567 c.-242A>G upstream_gene_variant 0.16 linezolid Uncertain significance
rplC 800570 c.-239C>G upstream_gene_variant 0.16 linezolid Uncertain significance
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.15 linezolid Uncertain significance
rplC 800582 c.-227C>G upstream_gene_variant 0.16 linezolid Uncertain significance
rplC 800589 c.-220A>C upstream_gene_variant 0.16 linezolid Uncertain significance
rplC 800597 c.-212A>T upstream_gene_variant 0.15 linezolid Uncertain significance
rplC 800600 c.-209G>C upstream_gene_variant 0.15 linezolid Uncertain significance
rplC 800610 c.-199_-197delCTAinsTTG upstream_gene_variant 0.18 linezolid Uncertain significance
rplC 800615 c.-194G>C upstream_gene_variant 0.17 linezolid Uncertain significance
rplC 800619 c.-190G>C upstream_gene_variant 0.17 linezolid Uncertain significance
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 isoniazid Not assoc w R
levofloxacin Not assoc w R
moxifloxacin Not assoc w R
rifampicin Not assoc w R
Rv1129c 1254582 c.-48A>G upstream_gene_variant 0.99 isoniazid Not assoc w R
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Not assoc w R
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
embR 1417554 c.-207C>G upstream_gene_variant 1.0 ethambutol Uncertain significance
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471878 n.33C>T non_coding_transcript_exon_variant 0.78 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.81 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471925 n.80delTinsAGTG non_coding_transcript_exon_variant 0.82 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471931 n.86G>C non_coding_transcript_exon_variant 0.82 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471933 n.88_89delGAinsCTGG non_coding_transcript_exon_variant 0.82 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472030 n.185delGinsATTTT non_coding_transcript_exon_variant 0.89 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.88 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472054 n.210_212delCGC non_coding_transcript_exon_variant 0.88 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.87 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472062 n.217G>T non_coding_transcript_exon_variant 0.87 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.88 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472104 n.259G>A non_coding_transcript_exon_variant 0.39 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.88 amikacin Not assoc w R
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.89 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.89 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.88 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.86 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472278 n.433C>T non_coding_transcript_exon_variant 0.75 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472279 n.434T>C non_coding_transcript_exon_variant 0.75 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.74 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.74 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.74 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.73 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.73 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472312 n.467G>T non_coding_transcript_exon_variant 0.14 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472313 n.468G>T non_coding_transcript_exon_variant 0.75 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472314 n.469A>T non_coding_transcript_exon_variant 0.17 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472315 n.471_472insTGT non_coding_transcript_exon_variant 0.71 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.76 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.76 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.72 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.77 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 0.77 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472443 n.598A>T non_coding_transcript_exon_variant 0.77 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472446 n.601T>G non_coding_transcript_exon_variant 0.77 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.77 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.77 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.78 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.77 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.76 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472466 n.621C>A non_coding_transcript_exon_variant 0.77 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472467 n.622G>C non_coding_transcript_exon_variant 0.77 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.78 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472485 n.640delGinsTA non_coding_transcript_exon_variant 0.79 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.81 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.82 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.84 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.85 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.85 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.9 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.9 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.9 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.9 amikacin Not assoc w R
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472671 n.826G>A non_coding_transcript_exon_variant 0.89 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472674 n.829_838delTTCCTTCCTTinsCCCTTCCAC non_coding_transcript_exon_variant 0.89 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472687 n.842A>G non_coding_transcript_exon_variant 0.89 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472689 n.844C>T non_coding_transcript_exon_variant 0.89 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.88 amikacin Not assoc w R
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.87 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472732 n.887G>A non_coding_transcript_exon_variant 0.4 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.8 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 0.77 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472838 n.994dupC non_coding_transcript_exon_variant 0.76 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472842 n.997G>A non_coding_transcript_exon_variant 0.74 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472843 n.998A>T non_coding_transcript_exon_variant 0.74 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472847 n.1002_1004delGTCinsCG non_coding_transcript_exon_variant 0.76 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472858 n.1013G>C non_coding_transcript_exon_variant 0.73 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.72 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472861 n.1016G>T non_coding_transcript_exon_variant 0.72 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472866 n.1023dupT non_coding_transcript_exon_variant 0.74 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472873 n.1028C>T non_coding_transcript_exon_variant 0.74 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472874 n.1029C>T non_coding_transcript_exon_variant 0.74 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 0.74 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.77 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.83 amikacin Not assoc w R
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.9 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472970 n.1125_1130delCGTAATinsATTCG non_coding_transcript_exon_variant 0.9 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472977 n.1132G>T non_coding_transcript_exon_variant 0.9 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.91 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.91 amikacin Not assoc w R
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.84 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473089 n.1244A>C non_coding_transcript_exon_variant 0.75 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473091 n.1246_1248delGGCinsCGTT non_coding_transcript_exon_variant 0.73 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473099 n.1254T>G non_coding_transcript_exon_variant 0.74 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473100 n.1255G>C non_coding_transcript_exon_variant 0.73 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.74 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.74 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473109 n.1264T>G non_coding_transcript_exon_variant 0.73 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.74 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473112 n.1267A>T non_coding_transcript_exon_variant 0.33 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.73 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473120 n.1275C>G non_coding_transcript_exon_variant 0.72 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.72 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473123 n.1278A>G non_coding_transcript_exon_variant 0.73 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473134 n.1289T>G non_coding_transcript_exon_variant 0.79 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473135 n.1290C>T non_coding_transcript_exon_variant 0.8 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.82 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.83 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.91 amikacin Not assoc w R
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473282 n.1438_1439insGTT non_coding_transcript_exon_variant 0.88 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473285 n.1441_1448delCCCTCGGG non_coding_transcript_exon_variant 0.89 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474182 n.525C>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474183 n.526T>G non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.529delA non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474199 n.542G>A non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474202 n.546dupA non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474253 n.596A>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474286 n.629_651delCTCCTTTTCCTCTCCGGAGGAGGinsACCTT non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474311 n.654_655insT non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474372 n.717_718insTTGT non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474384 n.727C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474487 n.830G>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474517 n.860C>G non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474784 n.1127C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474793 n.1136C>T non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474798 n.1141C>G non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474825 n.1168G>A non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.82 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474917 n.1260G>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474918 n.1261T>C non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474921 n.1264C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474953 n.1296C>A non_coding_transcript_exon_variant 0.15 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475057 n.1400G>A non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475060 n.1404delC non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475063 n.1406A>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475076 n.1419C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475094 n.1437C>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475108 n.1451C>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475110 n.1454_1457delGGCC non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475118 n.1461C>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475120 n.1463_1464insTCTT non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475137 n.1480A>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475170 n.1513A>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475197 n.1540G>A non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475202 n.1545G>C non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475696 n.2039T>A non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475699 n.2042delCinsGTT non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475703 n.2046A>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475704 n.2047C>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475758 n.2101_2112delACCCGCAAGGGTinsGGACATTGTCC non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475879 n.2222T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.82 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475989 n.2332T>C non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475990 n.2333G>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476023 n.2366C>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476024 n.2367T>G non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476029 n.2372A>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476077 n.2420T>C non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476082 n.2425T>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476087 n.2430C>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476097 n.2440C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476100 n.2443A>C non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476116 n.2459A>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.89 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.87 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.87 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476210 n.2555_2556dupTG non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.92 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476307 n.2650A>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.91 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.9 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476524 n.2867_2868delCAinsT non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476535 n.2878G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.83 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.82 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.66 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476624 n.2967T>A non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833928 c.387G>C synonymous_variant 0.11 pyrazinamide Uncertain significance
rpsA 1833949 c.408T>C synonymous_variant 0.44 pyrazinamide Uncertain significance
rpsA 1833955 c.414G>C synonymous_variant 0.5 pyrazinamide Uncertain significance
rpsA 1833970 c.429G>C synonymous_variant 0.54 pyrazinamide Uncertain significance
rpsA 1833979 c.438T>C synonymous_variant 0.57 pyrazinamide Uncertain significance
rpsA 1833988 c.447C>G synonymous_variant 0.61 pyrazinamide Uncertain significance
rpsA 1833991 c.450C>A synonymous_variant 0.62 pyrazinamide Uncertain significance
rpsA 1834009 c.468C>T synonymous_variant 0.63 pyrazinamide Uncertain significance
rpsA 1834012 c.471G>C synonymous_variant 0.62 pyrazinamide Uncertain significance
rpsA 1834015 c.474G>C synonymous_variant 0.61 pyrazinamide Uncertain significance
rpsA 1834025 p.Gln162Asp missense_variant 0.59 pyrazinamide Uncertain significance
rpsA 1834030 c.489C>G synonymous_variant 0.6 pyrazinamide Uncertain significance
rpsA 1834040 p.Lys167Gln missense_variant 0.62 pyrazinamide Uncertain significance
rpsA 1834046 p.Ile169Leu missense_variant 0.61 pyrazinamide Uncertain significance
rpsA 1834054 c.513C>G synonymous_variant 0.62 pyrazinamide Uncertain significance
rpsA 1834076 p.Asn179His missense_variant 0.58 pyrazinamide Uncertain significance
rpsA 1834093 c.552G>C synonymous_variant 0.5 pyrazinamide Uncertain significance
rpsA 1834102 c.561T>C synonymous_variant 0.35 pyrazinamide Uncertain significance
rpsA 1834105 c.564C>T synonymous_variant 0.32 pyrazinamide Uncertain significance
rpsA 1834110 p.Trp190Tyr missense_variant 0.29 pyrazinamide Uncertain significance
rpsA 1834118 p.Gln193Glu missense_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834131 p.Glu197Ala missense_variant 0.12 pyrazinamide Uncertain significance
rpsA 1834183 c.642T>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
rpsA 1834195 c.654G>C synonymous_variant 0.3 pyrazinamide Uncertain significance
rpsA 1834210 c.669C>T synonymous_variant 0.34 pyrazinamide Uncertain significance
rpsA 1834234 c.693G>C synonymous_variant 0.4 pyrazinamide Uncertain significance
rpsA 1834240 c.699T>C synonymous_variant 0.39 pyrazinamide Uncertain significance
rpsA 1834249 c.708T>C synonymous_variant 0.35 pyrazinamide Uncertain significance
rpsA 1834255 c.714C>T synonymous_variant 0.34 pyrazinamide Uncertain significance
rpsA 1834261 c.720A>G synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.34 pyrazinamide Uncertain significance
rpsA 1834294 c.753G>T synonymous_variant 0.39 pyrazinamide Uncertain significance
rpsA 1834298 p.Gln253Ala missense_variant 0.38 pyrazinamide Uncertain significance
rpsA 1834303 c.762T>G synonymous_variant 0.37 pyrazinamide Uncertain significance
rpsA 1834306 c.765T>C synonymous_variant 0.36 pyrazinamide Uncertain significance
rpsA 1834321 c.780C>G synonymous_variant 0.35 pyrazinamide Uncertain significance
rpsA 1834451 c.910_912delTTGinsCTC synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834456 c.915T>C synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834465 c.924T>C synonymous_variant 0.32 pyrazinamide Uncertain significance
rpsA 1834468 c.927A>G synonymous_variant 0.33 pyrazinamide Uncertain significance
rpsA 1834489 c.948T>C synonymous_variant 0.31 pyrazinamide Uncertain significance
rpsA 1834492 c.951C>T synonymous_variant 0.3 pyrazinamide Uncertain significance
rpsA 1834501 c.960G>C synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1834504 c.963G>C synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1834522 c.981C>T synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834523 p.Glu328Gln missense_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834528 c.987T>C synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834534 c.993C>G synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834540 c.999G>C synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834543 c.1002C>G synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834546 c.1005T>C synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834552 c.1011G>T synonymous_variant 0.24 pyrazinamide Uncertain significance
rpsA 1834555 c.1014T>C synonymous_variant 0.24 pyrazinamide Uncertain significance
rpsA 1834556 p.Ala339Asn missense_variant 0.24 pyrazinamide Uncertain significance
rpsA 1834567 p.Asp342Glu missense_variant 0.24 pyrazinamide Uncertain significance
rpsA 1834570 p.Asp343Glu missense_variant 0.24 pyrazinamide Uncertain significance
rpsA 1834572 p.Ala344Val missense_variant 0.24 pyrazinamide Uncertain significance
rpsA 1834603 p.Glu354Asp missense_variant 0.17 pyrazinamide Uncertain significance
rpsA 1834637 p.Asn366Asp missense_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834649 p.Thr370Val missense_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834663 c.1122C>T synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834688 c.1147_1149delAGTinsTCC synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834720 c.1179C>G synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834859 p.Ala440Thr missense_variant 1.0 pyrazinamide Uncertain significance
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
bacA 2062922 p.Ile603Val missense_variant 1.0 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Not assoc w R
streptomycin Not assoc w R
ndh 2102706 p.Asp113His missense_variant 1.0 delamanid Uncertain significance
ethionamide Uncertain significance
isoniazid Uncertain significance
ndh 2103173 c.-132delG upstream_gene_variant 1.0 delamanid Uncertain significance
ethionamide Uncertain significance
isoniazid Uncertain significance
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Not assoc w R
katG 2155503 c.609C>T synonymous_variant 1.0 isoniazid Not assoc w R
katG 2156025 c.87C>A synonymous_variant 1.0 isoniazid Not assoc w R
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Not assoc w R
PPE35 2168011 p.Ser868Arg missense_variant 1.0 pyrazinamide Uncertain significance
PPE35 2168814 c.1798dupA frameshift_variant 1.0 pyrazinamide Uncertain significance
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
Rv1979c 2223293 c.-129A>G upstream_gene_variant 0.99 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
kasA 2518132 c.18C>T synonymous_variant 1.0 isoniazid Uncertain significance
Rv2477c 2782441 p.Glu534Ala missense_variant 0.15 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2782451 p.Ala531Asp missense_variant 0.15 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2782483 p.Ala520Gly missense_variant 0.15 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2782487 c.1555_1556insTGGAAG conservative_inframe_insertion 0.15 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2782492 c.1542_1550delTGACGACGA disruptive_inframe_deletion 0.16 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2782510 c.1533G>C synonymous_variant 0.15 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2782522 c.1521G>C synonymous_variant 0.19 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2782528 c.1515G>C synonymous_variant 0.2 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2782537 c.1506T>G synonymous_variant 0.19 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2782540 c.1503T>C synonymous_variant 0.19 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2782546 c.1497C>T synonymous_variant 0.19 amikacin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
Rv2477c 2782549 c.1494T>C synonymous_variant 0.2 amikacin Uncertain significance
ethambutol Not assoc w R - Interim
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Not assoc w R - Interim
streptomycin Uncertain significance
Rv2477c 2782555 c.1488G>T synonymous_variant 0.19 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2782558 c.1485T>C synonymous_variant 0.19 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2782576 c.1467C>G synonymous_variant 0.17 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2782927 c.1116A>G synonymous_variant 0.98 amikacin Not assoc w R - Interim
ethambutol Not assoc w R
kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
rifampicin Not assoc w R
streptomycin Not assoc w R
Rv2681 2997325 p.Ala196Val missense_variant 1.0 capreomycin Uncertain significance
Rv2752c 3065372 p.Arg274Gly missense_variant 1.0 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3066574 c.-383T>C upstream_gene_variant 1.0 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
ald 3086728 c.-92C>T upstream_gene_variant 1.0 cycloserine Uncertain significance
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine Uncertain significance
ald 3087084 c.266delA frameshift_variant 1.0 cycloserine Uncertain significance
Rv3083 3448783 p.Val94Ile missense_variant 1.0 ethionamide Uncertain significance
lpqB 3623730 p.Ser394Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3624350 c.561G>T synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R
lpqB 3624486 p.Asp142Gly missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3624593 c.318G>A synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R
lpqB 3624710 c.201G>A synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
alr 3841474 c.-126T>G upstream_gene_variant 1.0 cycloserine Uncertain significance
rpoA 3878630 c.-124delC upstream_gene_variant 0.98 rifampicin Not assoc w R
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038671 c.2034T>C synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4038683 c.2022T>C synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4038686 c.2019C>T synonymous_variant 0.36 pyrazinamide Uncertain significance
clpC1 4038694 p.Ser671Ala missense_variant 0.44 pyrazinamide Uncertain significance
clpC1 4038704 c.2001T>C synonymous_variant 0.48 pyrazinamide Uncertain significance
clpC1 4038707 c.1998C>G synonymous_variant 0.49 pyrazinamide Uncertain significance
clpC1 4038710 c.1995G>C synonymous_variant 0.48 pyrazinamide Uncertain significance
clpC1 4038713 c.1992T>C synonymous_variant 0.47 pyrazinamide Uncertain significance
clpC1 4038743 p.Thr654Asn missense_variant 0.52 pyrazinamide Uncertain significance
clpC1 4038749 c.1956C>T synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
clpC1 4038755 c.1950G>C synonymous_variant 0.54 pyrazinamide Uncertain significance
clpC1 4038766 p.Leu647Val missense_variant 0.54 pyrazinamide Uncertain significance
clpC1 4038767 p.Arg646His missense_variant 0.55 pyrazinamide Uncertain significance
clpC1 4038773 p.Asp644Glu missense_variant 0.56 pyrazinamide Uncertain significance
clpC1 4038776 c.1929G>A synonymous_variant 0.56 pyrazinamide Uncertain significance
clpC1 4038788 c.1917G>C synonymous_variant 0.58 pyrazinamide Uncertain significance
clpC1 4038794 p.Ser637Thr missense_variant 0.58 pyrazinamide Uncertain significance
clpC1 4038811 p.Gln632Lys missense_variant 0.6 pyrazinamide Uncertain significance
clpC1 4038812 c.1893T>C synonymous_variant 0.59 pyrazinamide Uncertain significance
clpC1 4038836 c.1869G>T synonymous_variant 0.5 pyrazinamide Uncertain significance
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 0.39 pyrazinamide Uncertain significance
clpC1 4038848 c.1857C>T synonymous_variant 0.38 pyrazinamide Not assoc w R - Interim
clpC1 4038860 c.1845G>C synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4038863 c.1842G>T synonymous_variant 0.41 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
clpC1 4038887 c.1818G>A synonymous_variant 0.32 pyrazinamide Uncertain significance
clpC1 4038890 c.1815G>A synonymous_variant 0.32 pyrazinamide Uncertain significance
clpC1 4038908 c.1797C>G synonymous_variant 0.32 pyrazinamide Uncertain significance
clpC1 4038911 c.1794G>T synonymous_variant 0.31 pyrazinamide Uncertain significance
clpC1 4038914 c.1791G>A synonymous_variant 0.32 pyrazinamide Uncertain significance
clpC1 4038923 c.1782A>C synonymous_variant 0.36 pyrazinamide Uncertain significance
clpC1 4038926 c.1779G>C synonymous_variant 0.35 pyrazinamide Uncertain significance
clpC1 4038932 c.1773G>C synonymous_variant 0.36 pyrazinamide Uncertain significance
clpC1 4038935 c.1770C>T synonymous_variant 0.34 pyrazinamide Uncertain significance
clpC1 4038941 c.1764G>C synonymous_variant 0.33 pyrazinamide Uncertain significance
clpC1 4038953 c.1752A>G synonymous_variant 0.31 pyrazinamide Uncertain significance
clpC1 4038956 c.1749T>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4038974 c.1731T>G synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4038979 p.Ala576Ser missense_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038989 c.1716T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038997 c.1708T>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4039001 p.Asn568Glu missense_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039007 c.1698G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039022 c.1683A>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039025 c.1680C>G synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039034 c.1671C>G synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039061 c.1644G>C synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4039724 c.981A>G synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039730 c.975C>G synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039742 c.963C>T synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039748 c.957G>C synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039751 c.954A>G synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039754 c.951G>C synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039760 c.945T>C synonymous_variant 0.33 pyrazinamide Uncertain significance
clpC1 4039769 c.936C>G synonymous_variant 0.37 pyrazinamide Uncertain significance
clpC1 4039778 c.927A>G synonymous_variant 0.37 pyrazinamide Uncertain significance
clpC1 4039784 p.Ile307Leu missense_variant 0.36 pyrazinamide Uncertain significance
clpC1 4039790 c.915C>T synonymous_variant 0.36 pyrazinamide Uncertain significance
clpC1 4039793 c.912C>A synonymous_variant 0.36 pyrazinamide Uncertain significance
clpC1 4039802 c.903G>C synonymous_variant 0.38 pyrazinamide Uncertain significance
clpC1 4039805 c.900C>T synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
clpC1 4039811 c.894C>G synonymous_variant 0.4 pyrazinamide Uncertain significance
clpC1 4039817 c.888A>T synonymous_variant 0.39 pyrazinamide Uncertain significance
clpC1 4039820 c.885T>G synonymous_variant 0.4 pyrazinamide Uncertain significance
clpC1 4039823 c.882T>C synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.42 pyrazinamide Uncertain significance
clpC1 4039838 p.Leu289Ile missense_variant 0.44 pyrazinamide Uncertain significance
clpC1 4039850 c.855T>C synonymous_variant 0.51 pyrazinamide Uncertain significance
clpC1 4039865 c.840T>C synonymous_variant 0.46 pyrazinamide Uncertain significance
clpC1 4039871 p.Thr278Gln missense_variant 0.45 pyrazinamide Uncertain significance
clpC1 4039898 c.807C>G synonymous_variant 0.44 pyrazinamide Uncertain significance
clpC1 4039910 c.795C>T synonymous_variant 0.32 pyrazinamide Uncertain significance
clpC1 4039916 c.789T>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4039925 c.780C>T synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4039929 c.775_776delAGinsTC synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4039943 c.762G>C synonymous_variant 0.26 pyrazinamide Uncertain significance
clpC1 4039946 c.759A>T synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039952 c.753T>C synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4039958 p.Thr249Ser missense_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039966 p.Leu247Val missense_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039973 p.Asp244Glu missense_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039979 c.726C>G synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4040045 c.660C>G synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4040048 c.657C>T synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
clpC1 4040063 c.642G>C synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
clpC1 4040087 c.618G>C synonymous_variant 0.29 pyrazinamide Uncertain significance
clpC1 4040090 c.615T>G synonymous_variant 0.29 pyrazinamide Uncertain significance
clpC1 4040093 c.612C>G synonymous_variant 0.29 pyrazinamide Not assoc w R - Interim
clpC1 4040108 c.597G>C synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4040117 c.588A>G synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4040123 p.Glu194Asp missense_variant 0.26 pyrazinamide Uncertain significance
clpC1 4040134 p.Ile191Val missense_variant 0.25 pyrazinamide Uncertain significance
clpC1 4040135 c.570C>T synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4040144 c.561G>C synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4040147 c.558A>G synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
clpC1 4040157 p.Met183Lys missense_variant 0.27 pyrazinamide Uncertain significance
clpC1 4040162 c.543G>C synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
clpC1 4040168 c.537G>C synonymous_variant 0.28 pyrazinamide Uncertain significance
clpC1 4040192 c.513C>G synonymous_variant 0.2 pyrazinamide Uncertain significance
glpK 4138377 p.Val460Ala missense_variant 1.0 ethambutol Not assoc w R
isoniazid Not assoc w R
levofloxacin Not assoc w R
moxifloxacin Not assoc w R
rifampicin Not assoc w R
streptomycin Not assoc w R
embC 4240671 p.Thr270Ile missense_variant 0.99 ethambutol Not assoc w R
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embC 4242970 c.3108C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4244220 c.988C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4246551 p.Asn13Ser missense_variant 1.0 ethambutol Not assoc w R
embB 4246864 c.351C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4247646 p.Glu378Ala missense_variant 1.0 ethambutol Not assoc w R
aftB 4267858 p.Ile327Val missense_variant 1.0 ethambutol Not assoc w R
ubiA 4269351 c.483C>T synonymous_variant 1.0 ethambutol Not assoc w R
ubiA 4269387 p.Glu149Asp missense_variant 1.0 ethambutol Not assoc w R
ubiA 4269606 c.228T>C synonymous_variant 1.0 ethambutol Not assoc w R
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
gid 4407588 c.615A>G synonymous_variant 1.0 streptomycin Not assoc w R