Run ID: SRR5153091
Sample name:
Date: 2024-10-05T01:04:55.688574
Number of reads: 2497639
Percentage reads mapped: 42.37
Median coverage: 49.0
Strain: lineage4.3.3
Spoligotype:
Drug-resistance: HR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4.3 | Euro-American (LAM) | None | 1.0 |
lineage4 | Euro-American | None | 1.0 |
lineage4.3.3 | Euro-American (LAM) | RD115 | 1.0 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | katG | p.Ser140Asn | Uncertain significance | Mutation from literature |
ethambutol | ||||
pyrazinamide | ||||
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
katG | 2155693 | p.Ser140Asn | missense_variant | 0.29 | isoniazid | Uncertain significance | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 434 | p.His145Arg | missense_variant | 1.0 | isoniazid | Uncertain significance |
gyrB | 6298 | c.1059C>T | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6306 | c.1067_1068insGAT | disruptive_inframe_insertion | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6310 | c.-992G>C | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6312 | p.Ile358Ser | missense_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6313 | c.1075_1077delTCG | conservative_inframe_deletion | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6328 | c.-974C>T | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6331 | c.-971A>G | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6334 | c.-968G>C | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6352 | c.1113C>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6763 | c.1524G>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6764 | p.Leu509Phe | missense_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6775 | c.-527G>T | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6787 | c.-515G>A | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6798 | p.Gly520Ala | missense_variant | 0.22 | levofloxacin | Not assoc w R |
moxifloxacin | Uncertain significance | |||||
gyrB | 6802 | c.1563G>A | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6811 | c.1572C>T | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6835 | c.-467C>T | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6844 | c.-458T>C | upstream_gene_variant | 0.12 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 8040 | p.Gly247Ser | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
Rv0565c | 657449 | p.Gly8Ser | missense_variant | 1.0 | ethionamide | Uncertain significance |
nusG | 734532 | c.279A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
nusG | 734538 | c.285C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
nusG | 734548 | p.Gln99Ser | missense_variant | 0.23 | rifampicin | |
nusG | 734556 | c.303C>T | synonymous_variant | 0.24 | rifampicin | |
nusG | 734559 | c.306T>C | synonymous_variant | 0.24 | rifampicin | |
nusG | 734571 | c.318C>G | synonymous_variant | 0.25 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760172 | c.366G>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 760181 | c.375T>G | synonymous_variant | 0.21 | rifampicin | |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 760185 | c.379C>T | synonymous_variant | 0.21 | rifampicin | |
rpoB | 760199 | c.393C>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760244 | c.438G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760253 | c.447T>A | synonymous_variant | 0.23 | rifampicin | |
rpoB | 760256 | c.450C>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760571 | c.765G>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.15 | rifampicin | |
rpoB | 760596 | p.Thr264Gln | missense_variant | 0.15 | rifampicin | |
rpoB | 761234 | c.1428G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761258 | c.1452G>A | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761264 | c.1458C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761273 | c.1467T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761288 | c.1482G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761289 | p.Ser495Ala | missense_variant | 0.27 | rifampicin | |
rpoB | 761294 | c.1488G>A | synonymous_variant | 0.32 | rifampicin | |
rpoB | 761318 | c.1512G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761339 | c.1533C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761345 | c.1539G>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 761346 | p.Val514Ile | missense_variant | 0.27 | rifampicin | |
rpoB | 761355 | p.Val517Leu | missense_variant | 0.26 | rifampicin | |
rpoB | 761360 | c.1554T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 0.25 | rifampicin | |
rpoB | 761370 | p.Ile522Val | missense_variant | 0.24 | rifampicin | |
rpoB | 761558 | c.1752C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761564 | c.1758G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 761582 | c.1776G>A | synonymous_variant | 0.27 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 761627 | c.1821C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 761633 | c.1827G>C | synonymous_variant | 0.38 | rifampicin | |
rpoB | 761643 | p.Val613Ile | missense_variant | 0.36 | rifampicin | Uncertain significance |
rpoB | 762002 | c.2196C>G | synonymous_variant | 0.15 | rifampicin | |
rpoB | 762003 | p.Asn733Gln | missense_variant | 0.17 | rifampicin | |
rpoB | 762011 | c.2205G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 762014 | c.2208C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 762020 | p.Glu738Asp | missense_variant | 0.14 | rifampicin | |
rpoB | 762026 | c.2220G>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 762041 | c.2235C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 762047 | c.2241G>A | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 762068 | c.2262C>T | synonymous_variant | 0.21 | rifampicin | |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 762104 | c.2298C>T | synonymous_variant | 0.22 | rifampicin | |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.29 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.28 | rifampicin | |
rpoB | 762137 | c.2331C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 762161 | c.2355C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 762188 | c.2382C>T | synonymous_variant | 0.31 | rifampicin | |
rpoB | 762221 | c.2415G>A | synonymous_variant | 0.35 | rifampicin | |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 762236 | c.2430G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 762254 | c.2448T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.47 | rifampicin | |
rpoB | 762275 | c.2469C>G | synonymous_variant | 0.45 | rifampicin | |
rpoB | 762290 | c.2484C>T | synonymous_variant | 0.4 | rifampicin | |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762335 | c.2529C>T | synonymous_variant | 0.25 | rifampicin | |
rpoC | 762470 | c.-900G>T | upstream_gene_variant | 0.26 | rifampicin | |
rpoB | 762920 | c.3114C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 762923 | c.3117C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 762947 | c.-423C>G | upstream_gene_variant | 0.46 | rifampicin | |
rpoB | 762962 | c.3156C>T | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 762983 | c.-387C>T | upstream_gene_variant | 0.6 | rifampicin | |
rpoB | 762989 | c.3183G>T | synonymous_variant | 0.59 | rifampicin | Not assoc w R - Interim |
rpoB | 762995 | c.3189G>C | synonymous_variant | 0.6 | rifampicin | Not assoc w R - Interim |
rpoC | 762998 | c.-372G>A | upstream_gene_variant | 0.57 | rifampicin | |
rpoB | 763004 | c.3198G>A | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 763025 | c.-345C>T | upstream_gene_variant | 0.36 | rifampicin | |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R |
rpoC | 763049 | c.-321G>A | upstream_gene_variant | 0.3 | rifampicin | |
rpoB | 763053 | c.3247T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 763074 | p.Thr1090Val | missense_variant | 0.18 | rifampicin | |
rpoC | 763079 | c.-291C>G | upstream_gene_variant | 0.18 | rifampicin | |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 763088 | c.3282C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 763094 | c.3288G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 763124 | c.-246C>T | upstream_gene_variant | 0.21 | rifampicin | |
rpoC | 763139 | c.-231C>T | upstream_gene_variant | 0.18 | rifampicin | |
rpoC | 763142 | c.-228C>G | upstream_gene_variant | 0.17 | rifampicin | |
rpoB | 763145 | c.3339G>A | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 763157 | c.3351G>T | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 763172 | c.3366G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 763501 | c.132C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763505 | c.136C>T | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763528 | c.159G>T | synonymous_variant | 0.31 | rifampicin | |
rpoC | 763531 | c.162G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R |
rpoC | 763534 | c.165T>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 763537 | c.168C>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763558 | c.189C>T | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 763561 | c.192G>A | synonymous_variant | 0.41 | rifampicin | |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763633 | c.264T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 763648 | c.279C>T | synonymous_variant | 0.28 | rifampicin | |
rpoC | 763651 | c.282C>T | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 763666 | c.297G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 763669 | c.300C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764059 | c.690G>T | synonymous_variant | 0.18 | rifampicin | |
rpoC | 764077 | c.708C>G | synonymous_variant | 0.17 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.17 | rifampicin | |
rpoC | 764084 | p.Asn239Val | missense_variant | 0.16 | rifampicin | |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764102 | p.Val245Gln | missense_variant | 0.18 | rifampicin | |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 764134 | c.765C>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 764140 | c.771C>T | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764387 | c.1018T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764398 | c.1029G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764404 | c.1035C>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036_1038delAGGinsCGC | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764428 | c.1059G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764435 | c.1066_1068delAGGinsCGA | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.55 | rifampicin | Not assoc w R - Interim |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 764548 | c.1179G>C | synonymous_variant | 0.51 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.53 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.54 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoC | 764578 | c.1209C>G | synonymous_variant | 0.52 | rifampicin | |
rpoC | 764626 | c.1257C>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 764644 | c.1275G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764662 | c.1293G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764677 | c.1308C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764680 | c.1311G>A | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764686 | c.1317C>T | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764701 | c.1332C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 764755 | c.1386C>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764779 | c.1410G>A | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764780 | c.1411_1412delAGinsTC | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764785 | c.1416C>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764791 | c.1422C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 764803 | c.1434C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764809 | c.1440C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764812 | c.1443C>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764827 | c.1458G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764851 | c.1482C>T | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764854 | c.1485G>T | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764869 | c.1500C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764875 | c.1506C>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 764887 | c.1518G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519_1521delTTGinsCTC | synonymous_variant | 0.35 | rifampicin | |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.46 | rifampicin | |
rpoC | 764912 | p.Met515Gln | missense_variant | 0.45 | rifampicin | Uncertain significance |
rpoC | 764935 | c.1566T>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 764953 | c.1584G>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.79 | rifampicin | Not assoc w R |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 765781 | c.2412C>T | synonymous_variant | 0.27 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>T | synonymous_variant | 0.28 | rifampicin | |
rpoC | 765817 | c.2448G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 765820 | c.2451G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765823 | c.2454C>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765844 | c.2475C>G | synonymous_variant | 0.46 | rifampicin | |
rpoC | 765871 | c.2502T>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 765875 | p.Val836Ile | missense_variant | 0.4 | rifampicin | Uncertain significance |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 765907 | c.2538G>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 765910 | c.2541G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 765934 | c.2565C>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 765940 | c.2571A>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765979 | c.2610C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.27 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 766390 | c.3021C>T | synonymous_variant | 0.3 | rifampicin | |
rpoC | 766408 | c.3039C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 766429 | c.3061_3062insCGG | disruptive_inframe_insertion | 0.28 | rifampicin | |
rpoC | 766435 | p.Glu1022Asp | missense_variant | 0.24 | rifampicin | Uncertain significance |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766456 | c.3087C>G | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766459 | c.3090G>T | synonymous_variant | 0.15 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 766742 | p.Gln1125Met | missense_variant | 0.16 | rifampicin | |
rpoC | 766753 | c.3384C>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 766754 | p.Glu1129Gln | missense_variant | 0.22 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766776 | p.Arg1136His | missense_variant | 0.28 | rifampicin | |
rpoC | 766799 | p.Ala1144Ser | missense_variant | 0.33 | rifampicin | Uncertain significance |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 766837 | c.3468G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 766843 | c.3474T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 766975 | c.3606C>G | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766978 | c.3609C>A | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766987 | c.3618G>A | synonymous_variant | 0.29 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 767002 | c.3633G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 767023 | c.3654C>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 767044 | c.3675G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 767059 | c.3690T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.43 | rifampicin | |
rpoC | 767065 | c.3696G>A | synonymous_variant | 0.43 | rifampicin | |
rpoC | 767071 | c.3702C>G | synonymous_variant | 0.47 | rifampicin | |
rpoC | 767092 | c.3723C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 767093 | c.3724_3725delAGinsTC | synonymous_variant | 0.3 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 767100 | p.Lys1244Arg | missense_variant | 0.27 | rifampicin | |
rpoC | 767106 | p.Asn1246Ile | missense_variant | 0.24 | rifampicin | |
rpoC | 767110 | c.3741T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 767113 | c.3744G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781628 | c.69T>C | synonymous_variant | 0.18 | streptomycin | Not assoc w R - Interim |
rpsL | 781631 | c.72G>C | synonymous_variant | 0.18 | streptomycin | |
rpsL | 781637 | c.78C>G | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781658 | c.99A>G | synonymous_variant | 0.15 | streptomycin | |
rpsL | 781802 | c.243G>C | synonymous_variant | 0.14 | streptomycin | |
rpsL | 781805 | c.246G>C | synonymous_variant | 0.14 | streptomycin | |
rpsL | 781814 | c.255C>T | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781817 | c.258G>T | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781829 | c.270G>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781835 | c.276T>C | synonymous_variant | 0.16 | streptomycin | Not assoc w R - Interim |
rpsL | 781841 | c.282C>T | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781853 | c.294C>T | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.15 | streptomycin | |
fbiC | 1303095 | c.165G>A | synonymous_variant | 1.0 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
embR | 1417942 | c.-595G>T | upstream_gene_variant | 1.0 | ethambutol | |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471914 | n.69A>G | non_coding_transcript_exon_variant | 0.35 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471918 | n.73A>T | non_coding_transcript_exon_variant | 0.35 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471922 | n.78delT | non_coding_transcript_exon_variant | 0.34 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 0.35 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1471931 | n.87delA | non_coding_transcript_exon_variant | 0.33 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.34 | kanamycin | |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471938 | n.93T>A | non_coding_transcript_exon_variant | 0.34 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471943 | n.98T>C | non_coding_transcript_exon_variant | 0.35 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471978 | n.133C>T | non_coding_transcript_exon_variant | 0.23 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471985 | n.140T>C | non_coding_transcript_exon_variant | 0.2 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471986 | n.141C>T | non_coding_transcript_exon_variant | 0.19 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472106 | n.261G>A | non_coding_transcript_exon_variant | 0.44 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.44 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472148 | n.303T>C | non_coding_transcript_exon_variant | 0.54 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.54 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472172 | n.327T>C | non_coding_transcript_exon_variant | 0.54 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472225 | n.380C>G | non_coding_transcript_exon_variant | 0.45 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472251 | n.406G>A | non_coding_transcript_exon_variant | 0.38 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472416 | n.571C>T | non_coding_transcript_exon_variant | 0.13 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472486 | n.641A>G | non_coding_transcript_exon_variant | 0.14 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472489 | n.644A>T | non_coding_transcript_exon_variant | 0.13 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472497 | n.652G>T | non_coding_transcript_exon_variant | 0.4 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472530 | n.685G>A | non_coding_transcript_exon_variant | 0.47 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1472580 | n.735C>A | non_coding_transcript_exon_variant | 0.59 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472597 | n.752G>A | non_coding_transcript_exon_variant | 0.63 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472612 | n.767G>T | non_coding_transcript_exon_variant | 0.68 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472682 | n.837T>A | non_coding_transcript_exon_variant | 0.62 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472683 | n.838T>C | non_coding_transcript_exon_variant | 0.62 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472880 | n.1035G>A | non_coding_transcript_exon_variant | 0.29 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472953 | n.1108G>A | non_coding_transcript_exon_variant | 0.62 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472957 | n.1112C>T | non_coding_transcript_exon_variant | 0.62 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.64 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.63 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473026 | n.1181T>C | non_coding_transcript_exon_variant | 0.67 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473088 | n.1243A>G | non_coding_transcript_exon_variant | 0.65 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473100 | n.1255G>A | non_coding_transcript_exon_variant | 0.62 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.62 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 0.62 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.61 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473121 | n.1276T>C | non_coding_transcript_exon_variant | 0.6 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
amikacin | Not assoc w R | |||||
rrs | 1473123 | n.1278A>T | non_coding_transcript_exon_variant | 0.61 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473173 | n.1328C>T | non_coding_transcript_exon_variant | 0.62 | kanamycin | Uncertain significance |
capreomycin | Not assoc w R | |||||
streptomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.61 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.52 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473291 | n.1446_1447insT | non_coding_transcript_exon_variant | 0.52 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 0.54 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrl | 1473696 | n.39T>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473698 | n.41G>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1473699 | n.42A>G | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473717 | n.60G>A | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473731 | n.74T>A | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473756 | n.99G>T | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473757 | n.100T>G | non_coding_transcript_exon_variant | 0.54 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473768 | n.111A>G | non_coding_transcript_exon_variant | 0.61 | capreomycin | |
linezolid | ||||||
rrl | 1473770 | n.113T>G | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473815 | n.158T>C | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473822 | n.165A>G | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473832 | n.175C>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473833 | n.176_177insT | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473844 | n.187C>T | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473870 | n.213G>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473871 | n.214T>C | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473876 | n.219G>A | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473887 | n.230delTinsCA | non_coding_transcript_exon_variant | 0.37 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>G | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473916 | n.259C>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473922 | n.265A>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1473923 | n.266C>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474135 | n.478G>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474174 | n.517A>G | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474183 | n.526T>C | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474184 | n.527C>T | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474186 | n.529A>G | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474201 | n.544T>C | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474218 | n.561T>A | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474348 | n.691C>T | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474351 | n.694G>T | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474353 | n.696A>G | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474359 | n.702C>G | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474387 | n.730C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474402 | n.745T>C | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474454 | n.797G>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474496 | n.839C>A | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474497 | n.840G>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474506 | n.849C>G | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474507 | n.850G>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474537 | n.880G>A | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474626 | n.969T>C | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474636 | n.979A>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474638 | n.981C>A | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1474639 | n.982G>C | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.13 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474803 | n.1146G>A | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>G | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474824 | n.1167A>G | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474825 | n.1168G>A | non_coding_transcript_exon_variant | 0.46 | capreomycin | |
linezolid | ||||||
rrl | 1474827 | n.1170C>T | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474831 | n.1174A>C | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474837 | n.1180A>G | non_coding_transcript_exon_variant | 0.51 | capreomycin | |
linezolid | ||||||
rrl | 1474896 | n.1239A>G | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474903 | n.1246T>C | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474904 | n.1247G>C | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474913 | n.1256T>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474932 | n.1275C>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475060 | n.1404delC | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475065 | n.1408G>A | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475067 | n.1410A>G | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475076 | n.1419C>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475079 | n.1422T>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475081 | n.1424C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475090 | n.1433A>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475113 | n.1456C>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475114 | n.1457C>T | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475116 | n.1459G>A | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475422 | n.1765A>G | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475443 | n.1786G>A | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475452 | n.1795C>A | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475460 | n.1803A>G | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475475 | n.1818C>T | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475479 | n.1822C>T | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475480 | n.1823A>T | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475481 | n.1824C>G | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475482 | n.1825A>G | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475531 | n.1874C>T | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475538 | n.1881T>A | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475539 | n.1882A>T | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475545 | n.1888T>G | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475550 | n.1893A>G | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475649 | n.1992A>G | non_coding_transcript_exon_variant | 0.14 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475655 | n.1998T>A | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475699 | n.2042C>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475735 | n.2078T>C | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475753 | n.2096C>G | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475758 | n.2101A>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475760 | n.2103_2110delCCGCAAGGinsGCTTCGGC | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475769 | n.2112T>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1475775 | n.2118G>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475791 | n.2134A>G | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475883 | n.2226A>T | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475884 | n.2227A>G | non_coding_transcript_exon_variant | 0.69 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475892 | n.2235A>G | non_coding_transcript_exon_variant | 0.73 | capreomycin | |
linezolid | ||||||
rrl | 1475897 | n.2240T>C | non_coding_transcript_exon_variant | 0.7 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475916 | n.2259C>T | non_coding_transcript_exon_variant | 0.71 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475975 | n.2318C>T | non_coding_transcript_exon_variant | 0.59 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.55 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476030 | n.2373A>G | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476032 | n.2375C>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1476034 | n.2377C>G | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476035 | n.2378G>C | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476044 | n.2387T>G | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476056 | n.2399G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476058 | n.2401T>C | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476088 | n.2431A>C | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476099 | n.2442A>G | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476103 | n.2446C>A | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476105 | n.2450delA | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1476110 | n.2453G>T | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476160 | n.2503T>C | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476194 | n.2537A>G | non_coding_transcript_exon_variant | 0.62 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476200 | n.2543A>T | non_coding_transcript_exon_variant | 0.64 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476201 | n.2544C>T | non_coding_transcript_exon_variant | 0.63 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476221 | n.2564T>C | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476251 | n.2594T>A | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476252 | n.2595T>G | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476256 | n.2599A>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.4 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476297 | n.2640C>G | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476298 | n.2641C>G | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476300 | n.2643G>A | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476301 | n.2644A>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476309 | n.2652G>C | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476524 | n.2867C>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | |
linezolid | ||||||
rrl | 1476525 | n.2868A>G | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476539 | n.2882A>G | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476540 | n.2883C>G | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476585 | n.2928A>G | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476614 | n.2957A>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | |
linezolid | ||||||
rrl | 1476616 | n.2959A>G | non_coding_transcript_exon_variant | 0.39 | capreomycin | |
linezolid | ||||||
rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476629 | n.2972C>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476630 | n.2973A>G | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476661 | n.3004A>G | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476665 | n.3008T>G | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476666 | n.3009C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rpsA | 1833571 | c.30A>G | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833580 | c.39C>T | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833589 | c.48A>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833596 | p.Ser19Ala | missense_variant | 0.15 | pyrazinamide | |
rpsA | 1833604 | c.63C>T | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833607 | c.66T>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833616 | c.75A>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1833619 | c.78A>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833623 | p.Lys28Ala | missense_variant | 0.17 | pyrazinamide | |
rpsA | 1833646 | c.105T>C | synonymous_variant | 0.21 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833652 | c.111C>T | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833769 | c.228C>G | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1833793 | c.252C>T | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1833799 | c.258C>G | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1833808 | c.267G>T | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833811 | c.270G>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833835 | c.294C>T | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1833859 | c.318C>G | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833862 | c.321G>T | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833886 | c.345C>G | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1833894 | p.Ala118Glu | missense_variant | 0.43 | pyrazinamide | |
rpsA | 1833919 | c.378C>T | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833920 | p.Lys127Arg | missense_variant | 0.29 | pyrazinamide | |
rpsA | 1833928 | c.387G>T | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1833931 | c.390C>G | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833949 | c.408T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833952 | c.411C>T | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833964 | c.423C>T | synonymous_variant | 0.35 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833970 | c.429G>T | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833991 | c.450C>G | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834012 | c.471G>C | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1834015 | c.474G>C | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1834034 | p.Ile165Val | missense_variant | 0.43 | pyrazinamide | |
rpsA | 1834093 | c.552G>T | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834099 | c.558C>G | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834117 | c.576G>A | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834213 | c.672G>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834234 | c.693G>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834264 | c.723G>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834279 | c.738C>T | synonymous_variant | 0.27 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834294 | c.753G>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834298 | p.Gln253Glu | missense_variant | 0.19 | pyrazinamide | |
rpsA | 1834303 | c.762T>G | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834307 | p.Asp256Thr | missense_variant | 0.17 | pyrazinamide | |
rpsA | 1834327 | c.786G>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834340 | p.Met267Leu | missense_variant | 0.23 | pyrazinamide | Uncertain significance |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834354 | c.813G>T | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834357 | c.816T>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834361 | c.820T>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.21 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834369 | c.828C>G | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834375 | c.834G>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834378 | c.837T>C | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834387 | c.846C>T | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834399 | p.His286Gln | missense_variant | 0.26 | pyrazinamide | |
rpsA | 1834408 | c.867C>T | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834451 | c.910_912delTTGinsCTC | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834456 | c.915T>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.48 | pyrazinamide | |
rpsA | 1834516 | c.975G>A | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834534 | c.993C>G | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1834540 | c.999G>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834543 | c.1002C>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834552 | c.1011G>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834555 | c.1014T>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834557 | p.Ala339Val | missense_variant | 0.24 | pyrazinamide | |
rpsA | 1834591 | c.1050C>T | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834597 | c.1056C>T | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834663 | c.1122C>T | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834667 | p.Ala376Ser | missense_variant | 0.26 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Pro | missense_variant | 0.38 | pyrazinamide | |
rpsA | 1834738 | c.1197A>G | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834759 | c.1218A>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834765 | p.Glu408Asp | missense_variant | 0.39 | pyrazinamide | |
rpsA | 1834776 | p.Ala412Glu | missense_variant | 0.37 | pyrazinamide | |
rpsA | 1834780 | c.1239A>G | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1834788 | p.Ala416Gly | missense_variant | 0.35 | pyrazinamide | |
rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1834804 | c.1263C>G | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834836 | p.Met432Thr | missense_variant | 0.77 | pyrazinamide | Not assoc w R - Interim |
tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.16 | linezolid | |
tsnR | 1853372 | c.-234A>G | upstream_gene_variant | 0.14 | linezolid | |
tsnR | 1853375 | c.-231G>T | upstream_gene_variant | 0.13 | linezolid | |
tsnR | 1853384 | c.-222G>C | upstream_gene_variant | 0.14 | linezolid | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
katG | 2155691 | c.421T>C | synonymous_variant | 0.36 | isoniazid | |
katG | 2155696 | p.Ala139Gly | missense_variant | 0.35 | isoniazid | |
katG | 2155716 | c.396T>G | synonymous_variant | 0.33 | isoniazid | |
katG | 2156196 | c.-85C>T | upstream_gene_variant | 0.98 | isoniazid | Not assoc w R |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
kasA | 2518919 | p.Gly269Ser | missense_variant | 1.0 | isoniazid | |
folC | 2746340 | p.Ala420Val | missense_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3073868 | p.Thr202Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 0.12 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626786 | p.Pro188Ala | missense_variant | 0.12 | rifampicin | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mtrB | 3626813 | c.-200C>G | upstream_gene_variant | 0.14 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627071 | c.-458G>C | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627089 | c.-476C>T | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627098 | c.252A>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627119 | c.231T>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627125 | c.-512C>G | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627128 | c.-515T>C | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627139 | c.-526T>C | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.29 | rifampicin | |
rpoA | 3877617 | c.891G>C | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3877638 | c.870T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoA | 3877647 | c.861C>T | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3877653 | c.855C>T | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3877656 | c.852T>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoA | 3877662 | c.846C>T | synonymous_variant | 0.32 | rifampicin | |
rpoA | 3877665 | c.843C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoA | 3877674 | c.834C>T | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3877686 | c.822A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoA | 3877893 | c.615C>G | synonymous_variant | 0.17 | rifampicin | |
rpoA | 3877896 | p.Pro204Ala | missense_variant | 0.16 | rifampicin | |
rpoA | 3877905 | c.603A>C | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3877908 | c.600T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoA | 3877926 | c.582G>C | synonymous_variant | 0.17 | rifampicin | |
rpoA | 3877932 | c.576G>C | synonymous_variant | 0.17 | rifampicin | |
rpoA | 3877936 | p.Lys191Arg | missense_variant | 0.17 | rifampicin | |
rpoA | 3877962 | c.546G>T | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoA | 3877971 | p.Asp179Glu | missense_variant | 0.13 | rifampicin | Uncertain significance |
rpoA | 3877974 | c.534G>C | synonymous_variant | 0.12 | rifampicin | |
rpoA | 3878244 | c.264G>A | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878247 | c.261G>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878256 | c.252G>C | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878264 | p.Ser82Gly | missense_variant | 0.25 | rifampicin | |
rpoA | 3878271 | c.237T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoA | 3878283 | p.Glu75Asp | missense_variant | 0.26 | rifampicin | Uncertain significance |
rpoA | 3878298 | c.210A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3878301 | c.207C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoA | 3878304 | c.204G>C | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoA | 3879058 | c.-551C>G | upstream_gene_variant | 0.14 | rifampicin | |
rpoA | 3879079 | c.-572A>T | upstream_gene_variant | 0.2 | rifampicin | |
rpoA | 3879088 | c.-583_-581delACAinsTCC | upstream_gene_variant | 0.2 | rifampicin | |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.2 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.2 | rifampicin | |
rpoA | 3879136 | c.-629A>G | upstream_gene_variant | 0.2 | rifampicin | |
clpC1 | 4038287 | c.2418C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R |
clpC1 | 4038755 | c.1950G>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4038767 | c.1938G>T | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038770 | c.1935C>G | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4038790 | c.1915C>T | synonymous_variant | 0.36 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038795 | p.Ser637Thr | missense_variant | 0.4 | pyrazinamide | |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.46 | pyrazinamide | |
clpC1 | 4038815 | c.1890G>T | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4038842 | c.1863G>C | synonymous_variant | 0.49 | pyrazinamide | |
clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.47 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.41 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038896 | c.1809C>T | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4038968 | c.1737G>A | synonymous_variant | 0.87 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039004 | c.1701C>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4039046 | c.1659C>T | synonymous_variant | 0.35 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039067 | c.1638G>C | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4039070 | c.1635G>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039082 | c.1623C>T | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4039085 | c.1620A>G | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039091 | c.1614G>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>T | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039136 | c.1569C>T | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.29 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>T | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039181 | c.1522_1524delTTGinsCTC | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039187 | c.1518G>T | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039190 | c.1515C>T | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039199 | p.Ala502Glu | missense_variant | 0.23 | pyrazinamide | |
clpC1 | 4039217 | c.1488G>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039220 | c.1485G>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039239 | p.Gly489Ala | missense_variant | 0.22 | pyrazinamide | |
clpC1 | 4039427 | p.Glu426Asp | missense_variant | 0.21 | pyrazinamide | |
clpC1 | 4039430 | c.1275T>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039436 | c.1269G>A | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039442 | c.1263A>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039448 | c.1257A>G | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039454 | c.1251A>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039463 | c.1242C>G | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039466 | c.1239T>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039517 | c.1188C>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039544 | c.1161C>T | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039586 | c.1119G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039589 | c.1116G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039598 | c.1107C>T | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039634 | p.Glu357Asn | missense_variant | 0.33 | pyrazinamide | |
clpC1 | 4039649 | c.1056G>C | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039652 | c.1053G>C | synonymous_variant | 0.4 | pyrazinamide | |
clpC1 | 4039661 | c.1044T>C | synonymous_variant | 0.42 | pyrazinamide | |
clpC1 | 4039688 | c.1017G>A | synonymous_variant | 0.46 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039694 | c.1011G>T | synonymous_variant | 0.45 | pyrazinamide | |
clpC1 | 4039700 | c.1005C>T | synonymous_variant | 0.45 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039733 | c.972G>C | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039742 | c.963C>T | synonymous_variant | 0.44 | pyrazinamide | |
clpC1 | 4039748 | c.957G>C | synonymous_variant | 0.48 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.47 | pyrazinamide | |
clpC1 | 4039757 | c.948A>G | synonymous_variant | 0.51 | pyrazinamide | |
clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.58 | pyrazinamide | |
clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.57 | pyrazinamide | |
clpC1 | 4039793 | c.912C>G | synonymous_variant | 0.53 | pyrazinamide | |
clpC1 | 4039817 | c.888A>T | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039820 | c.885T>G | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4039832 | c.873C>G | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039835 | c.870C>T | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4039868 | c.837C>T | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039880 | c.825G>A | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039913 | c.792C>T | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039937 | c.768G>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039940 | c.765G>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039943 | c.762G>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039946 | c.759A>T | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4039955 | c.750G>C | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4039958 | c.747G>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4039979 | c.726C>G | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4039985 | c.720G>A | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4039991 | c.714G>C | synonymous_variant | 0.36 | pyrazinamide | |
clpC1 | 4040002 | p.His235Asn | missense_variant | 0.31 | pyrazinamide | |
clpC1 | 4040003 | c.702G>C | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4040015 | c.690G>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.21 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040027 | c.678C>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040030 | c.675C>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040042 | c.663C>T | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040048 | c.657C>T | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040057 | c.648C>T | synonymous_variant | 0.2 | pyrazinamide | |
glpK | 4139015 | c.741G>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
gid | 4408156 | p.Leu16Arg | missense_variant | 1.0 | streptomycin | Not assoc w R |