TB-Profiler result

Run: ERR1023502
Summary

Run ID: ERR1023502

Sample name:

Date: 31-03-2023 09:24:34

Number of reads: 233512

Percentage reads mapped: 4.48

Strain: lineage2.2.1

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 0.17
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 0.1
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.64 rifampicin
rpoB 761139 p.His445Tyr missense_variant 0.36 rifampicin
rpoB 761196 p.Leu464Met missense_variant 0.79 rifampicin
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.99 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.98 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.96 kanamycin, capreomycin, aminoglycosides, amikacin
fabG1 1673425 c.-15C>T upstream_gene_variant 1.0 isoniazid, ethionamide
katG 2155693 p.Ser140Asn missense_variant 0.91 isoniazid
ethR 4327831 p.Ala95Thr missense_variant 1.0 ethionamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6266 p.Pro343Asp missense_variant 0.73
gyrB 6280 c.1041T>C synonymous_variant 0.79
gyrB 6283 p.Asp348Glu missense_variant 0.79
gyrB 6286 c.1047T>C synonymous_variant 0.79
gyrB 6292 c.1053G>C synonymous_variant 0.79
gyrB 6295 c.1056A>G synonymous_variant 0.79
gyrB 6298 c.1059C>T synonymous_variant 0.85
gyrB 6302 p.Ala355Thr missense_variant 0.86
gyrA 6307 c.-995T>G upstream_gene_variant 0.86
gyrA 6310 c.-992G>C upstream_gene_variant 0.8
gyrA 6319 c.-983G>C upstream_gene_variant 0.8
gyrB 6326 p.Ser363Gly missense_variant 0.8
gyrA 6331 c.-971A>G upstream_gene_variant 0.8
gyrA 6362 c.-940_-938delTTGinsCTC upstream_gene_variant 0.81
gyrB 6371 p.Thr378Ser missense_variant 0.87
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8279 c.978G>C synonymous_variant 0.67
gyrA 8283 p.Ile328Leu missense_variant 0.67
gyrA 8288 c.987T>C synonymous_variant 0.67
gyrA 8294 c.993T>C synonymous_variant 0.67
gyrA 8315 c.1015_1016delAC frameshift_variant 1.0
gyrA 8324 c.1023T>C synonymous_variant 1.0
gyrA 8330 c.1029C>G synonymous_variant 0.67
gyrA 8339 c.1038A>C synonymous_variant 0.67
gyrA 8343 p.Ile348Leu missense_variant 0.67
gyrA 8351 p.Asp350Glu missense_variant 0.67
gyrA 8354 c.1053G>T synonymous_variant 0.67
fgd1 491295 c.513C>G synonymous_variant 0.67
fgd1 491310 c.528C>G synonymous_variant 0.67
fgd1 491316 c.534C>G synonymous_variant 0.67
fgd1 491320 p.Ala180Gln missense_variant 0.67
fgd1 491325 c.543G>C synonymous_variant 0.75
fgd1 491328 c.546C>G synonymous_variant 0.75
fgd1 491344 p.Ala188Met missense_variant 0.75
fgd1 491349 c.567T>C synonymous_variant 0.75
fgd1 491356 p.Phe192Val missense_variant 0.75
fgd1 491364 c.582T>C synonymous_variant 0.75
fgd1 491367 c.585G>C synonymous_variant 0.75
fgd1 491380 p.Glu200Met missense_variant 0.75
fgd1 491394 c.612C>G synonymous_variant 0.75
fgd1 491397 p.Glu205Asp missense_variant 0.75
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575907 p.Ala187Val missense_variant 1.0
rpoB 760143 p.Val113Ile missense_variant 0.67
rpoB 760148 p.Asp114Glu missense_variant 0.86
rpoB 760157 c.351A>G synonymous_variant 0.92
rpoB 760160 p.Asp118Glu missense_variant 0.92
rpoB 760172 c.366G>C synonymous_variant 0.92
rpoB 760176 p.Ala124Ser missense_variant 0.92
rpoB 760184 c.378A>G synonymous_variant 0.88
rpoB 760196 c.390C>G synonymous_variant 0.89
rpoB 760199 c.393C>G synonymous_variant 0.89
rpoB 760208 p.Ile134Met missense_variant 0.89
rpoB 760235 c.429T>C synonymous_variant 0.89
rpoB 760263 p.Met153Leu missense_variant 0.89
rpoB 760274 p.Glu156Asp missense_variant 0.5
rpoB 760390 p.Ser195Thr missense_variant 0.5
rpoB 760393 p.Val196Ala missense_variant 0.71
rpoB 760400 c.594G>C synonymous_variant 0.89
rpoB 760424 c.618C>G synonymous_variant 0.91
rpoB 760430 c.624T>C synonymous_variant 0.87
rpoB 760433 p.Asp209Glu missense_variant 0.87
rpoB 760434 p.Val210Ile missense_variant 0.87
rpoB 760450 p.Thr215Ile missense_variant 0.83
rpoB 760464 p.Ile220Val missense_variant 0.87
rpoB 760475 c.669A>G synonymous_variant 0.87
rpoB 760479 p.Arg225Lys missense_variant 0.87
rpoB 760484 c.678A>G synonymous_variant 0.87
rpoB 760485 p.Pro227Ser missense_variant 0.87
rpoB 760502 c.696C>G synonymous_variant 0.8
rpoB 760508 c.702G>C synonymous_variant 0.83
rpoB 760584 p.Asn260His missense_variant 0.33
rpoB 760591 p.Val262Ala missense_variant 0.33
rpoB 760596 p.Thr264Gln missense_variant 0.33
rpoB 760607 c.801G>C synonymous_variant 0.33
rpoB 760611 c.805_807delTTGinsCTC synonymous_variant 0.33
rpoB 760634 c.828T>C synonymous_variant 0.85
rpoB 760646 c.840C>G synonymous_variant 0.91
rpoB 760655 c.849A>G synonymous_variant 0.9
rpoB 760659 p.Ser285Ala missense_variant 0.9
rpoB 760664 c.858G>C synonymous_variant 0.9
rpoB 760674 c.868T>C synonymous_variant 0.8
rpoB 760679 p.Glu291Asp missense_variant 0.8
rpoB 760683 c.877_879delTTGinsCTT synonymous_variant 0.73
rpoB 760687 p.Phe294Tyr missense_variant 0.8
rpoB 760694 p.Lys296Asn missense_variant 0.8
rpoB 760696 p.Glu297Gly missense_variant 0.8
rpoB 760703 c.897C>G synonymous_variant 0.8
rpoB 760716 p.Arg304Lys missense_variant 0.78
rpoB 760730 c.924T>C synonymous_variant 0.78
rpoB 760734 p.Val310Ile missense_variant 0.7
rpoB 760916 c.1110C>T synonymous_variant 0.9
rpoB 760925 c.1119T>C synonymous_variant 0.9
rpoB 760927 p.Thr374Ser missense_variant 0.9
rpoB 760940 c.1134G>C synonymous_variant 0.9
rpoB 760946 c.1140A>G synonymous_variant 0.9
rpoB 760953 p.Ile383Val missense_variant 0.94
rpoB 760958 c.1152G>C synonymous_variant 0.94
rpoB 760959 p.Val385Thr missense_variant 0.94
rpoB 760965 p.Met387Leu missense_variant 0.94
rpoB 760982 c.1176G>C synonymous_variant 0.97
rpoB 760985 c.1179G>C synonymous_variant 0.97
rpoB 760988 c.1182C>G synonymous_variant 0.97
rpoB 760991 c.1185G>C synonymous_variant 0.97
rpoB 761015 c.1209G>C synonymous_variant 0.95
rpoB 761021 c.1215G>C synonymous_variant 0.96
rpoB 761027 c.1221A>G synonymous_variant 0.96
rpoB 761036 c.1230G>C synonymous_variant 0.96
rpoB 761037 c.1231T>C synonymous_variant 0.96
rpoB 761057 c.1251G>C synonymous_variant 0.95
rpoB 761064 p.Ala420Ser missense_variant 0.95
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.91
rpoB 761102 c.1296A>G synonymous_variant 0.91
rpoB 761123 c.1317G>C synonymous_variant 0.76
rpoB 761126 c.1320G>C synonymous_variant 0.64
rpoB 761133 c.1327T>C synonymous_variant 0.64
rpoB 761138 c.1332C>G synonymous_variant 0.64
rpoB 761147 c.1341C>T synonymous_variant 0.33
rpoB 761165 c.1359G>C synonymous_variant 0.4
rpoB 761168 c.1362C>G synonymous_variant 0.67
rpoB 761171 c.1365C>T synonymous_variant 0.75
rpoB 761180 c.1374A>C synonymous_variant 0.75
rpoB 761186 p.Glu460Asp missense_variant 0.75
rpoB 761189 c.1383T>C synonymous_variant 0.67
rpoB 761195 c.1389G>C synonymous_variant 0.67
rpoB 761207 c.1401C>T synonymous_variant 0.88
rpoB 761213 c.1407G>C synonymous_variant 0.88
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.88
rpoB 761234 c.1428G>C synonymous_variant 0.91
rpoB 761249 c.1443A>G synonymous_variant 0.91
rpoB 761255 c.1449T>C synonymous_variant 0.94
rpoB 761261 c.1455G>T synonymous_variant 0.94
rpoB 761289 p.Ser495Ala missense_variant 0.94
rpoB 761292 p.Val496Ser missense_variant 0.91
rpoB 761299 p.Ala498Gly missense_variant 0.91
rpoB 761304 p.Val500Ile missense_variant 0.88
rpoB 761322 p.Ile506Val missense_variant 0.83
rpoB 761327 c.1521A>G synonymous_variant 0.83
rpoB 761330 c.1524G>T synonymous_variant 0.83
rpoB 761333 c.1527G>C synonymous_variant 0.83
rpoB 761345 c.1539G>C synonymous_variant 0.8
rpoB 761349 p.Asp515Lys missense_variant 0.67
rpoB 761355 p.Val517Lys missense_variant 0.75
rpoB 761360 c.1554T>G synonymous_variant 0.75
rpoB 761362 p.Ser519Thr missense_variant 0.75
rpoB 761370 p.Ile522Val missense_variant 0.75
rpoB 761375 c.1569G>C synonymous_variant 0.75
rpoB 761382 p.Thr526Ser missense_variant 0.67
rpoB 761516 c.1710G>C synonymous_variant 0.9
rpoB 761534 c.1728G>C synonymous_variant 0.97
rpoB 761535 p.Pro577Ala missense_variant 0.97
rpoB 761554 p.Val583Ala missense_variant 0.94
rpoB 761558 c.1752C>G synonymous_variant 0.94
rpoB 761565 p.Met587Leu missense_variant 0.94
rpoB 761570 c.1764T>C synonymous_variant 0.94
rpoB 761573 c.1767C>G synonymous_variant 0.94
rpoB 761596 p.Asn597Ser missense_variant 0.97
rpoB 761600 c.1794T>C synonymous_variant 0.97
rpoB 761603 c.1797C>G synonymous_variant 0.97
rpoB 761612 c.1806G>C synonymous_variant 0.97
rpoB 761615 c.1809A>C synonymous_variant 0.97
rpoB 761627 c.1821C>T synonymous_variant 0.97
rpoB 761633 c.1827G>C synonymous_variant 1.0
rpoB 761645 c.1839C>G synonymous_variant 1.0
rpoB 761933 c.2127G>C synonymous_variant 0.71
rpoB 761948 c.2142G>C synonymous_variant 0.95
rpoB 761954 c.2148C>G synonymous_variant 0.96
rpoB 761955 p.Ile717Phe missense_variant 0.96
rpoB 762002 c.2196C>G synonymous_variant 0.97
rpoB 762003 p.Asn733Gln missense_variant 0.97
rpoB 762011 c.2205G>C synonymous_variant 0.97
rpoB 762014 c.2208C>G synonymous_variant 0.97
rpoB 762015 p.Glu737Gln missense_variant 0.97
rpoB 762020 p.Glu738Asp missense_variant 0.97
rpoB 762029 c.2223C>G synonymous_variant 0.97
rpoB 762030 p.Thr742Ser missense_variant 0.97
rpoB 762053 c.2247T>C synonymous_variant 0.96
rpoB 762062 c.2256T>C synonymous_variant 0.96
rpoB 762065 c.2259T>C synonymous_variant 0.95
rpoB 762083 c.2277T>C synonymous_variant 0.93
rpoB 762084 p.Ala760Pro missense_variant 0.93
rpoB 762101 c.2295C>G synonymous_variant 0.94
rpoB 762114 p.Ile770Val missense_variant 0.95
rpoB 762122 p.Asp772Glu missense_variant 0.95
rpoB 762128 c.2322G>C synonymous_variant 0.95
rpoB 762131 c.2325C>G synonymous_variant 0.95
rpoB 762140 c.2334G>C synonymous_variant 0.95
rpoB 762143 c.2337T>C synonymous_variant 0.95
rpoB 762149 c.2343G>C synonymous_variant 0.93
rpoB 762156 p.Val784Met missense_variant 0.6
rpoB 762167 c.2361T>C synonymous_variant 0.78
rpoB 762170 c.2364C>G synonymous_variant 0.85
rpoB 762176 c.2370T>G synonymous_variant 0.89
rpoB 762185 c.2379G>C synonymous_variant 0.92
rpoB 762189 p.Ile795Leu missense_variant 0.93
rpoB 762209 c.2403C>G synonymous_variant 0.95
rpoB 762212 c.2406G>C synonymous_variant 0.96
rpoB 762218 c.2412T>C synonymous_variant 0.96
rpoB 762233 c.2427G>C synonymous_variant 0.96
rpoB 762245 c.2439G>C synonymous_variant 0.96
rpoB 762254 c.2448T>C synonymous_variant 0.96
rpoB 762266 c.2460T>C synonymous_variant 0.98
rpoB 762287 c.2481C>T synonymous_variant 1.0
rpoB 762293 c.2487T>C synonymous_variant 1.0
rpoB 762297 p.Leu831Met missense_variant 1.0
rpoB 762317 c.2511A>G synonymous_variant 1.0
rpoB 762318 p.Ser838Thr missense_variant 1.0
rpoB 762325 p.Lys840Thr missense_variant 0.92
rpoB 762329 c.2523G>C synonymous_variant 0.92
rpoB 762336 p.Ile844Val missense_variant 0.83
rpoB 762339 p.Arg845Lys missense_variant 0.83
rpoB 762347 c.2541T>C synonymous_variant 0.83
rpoB 762348 p.Ser848Asp missense_variant 0.83
rpoB 762362 p.Glu852Asp missense_variant 0.83
rpoB 762369 c.2563T>C synonymous_variant 0.83
rpoB 762375 p.Ala857Pro missense_variant 0.83
rpoC 762380 c.-990T>C upstream_gene_variant 0.83
rpoB 762387 p.Glu861Gln missense_variant 0.83
rpoB 762849 p.Tyr1015Asp missense_variant 0.9
rpoB 762858 p.Thr1018Ala missense_variant 0.94
rpoC 762863 c.-507T>C upstream_gene_variant 0.91
rpoB 762879 p.Met1025Leu missense_variant 0.95
rpoC 762887 c.-483G>C upstream_gene_variant 0.96
rpoC 762899 c.-471G>C upstream_gene_variant 0.98
rpoC 762917 c.-453C>G upstream_gene_variant 0.98
rpoC 762923 c.-447C>G upstream_gene_variant 0.98
rpoC 762929 c.-441G>C upstream_gene_variant 0.98
rpoC 762947 c.-423C>G upstream_gene_variant 0.98
rpoC 762971 c.-399G>C upstream_gene_variant 0.93
rpoC 762995 c.-375G>C upstream_gene_variant 0.83
rpoB 763005 p.Cys1067Gly missense_variant 0.5
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763444 c.75T>C synonymous_variant 0.38
rpoC 763456 c.87A>G synonymous_variant 0.81
rpoC 763468 c.99G>C synonymous_variant 0.88
rpoC 763483 c.114G>C synonymous_variant 0.93
rpoC 763486 c.117T>C synonymous_variant 0.93
rpoC 763492 c.123G>C synonymous_variant 0.93
rpoC 763507 c.138G>C synonymous_variant 0.96
rpoC 763528 c.159G>C synonymous_variant 0.96
rpoC 763531 c.162G>C synonymous_variant 0.96
rpoC 763534 c.165T>C synonymous_variant 0.96
rpoC 763537 c.168C>G synonymous_variant 0.96
rpoC 763546 c.177A>G synonymous_variant 0.97
rpoC 763573 c.204G>C synonymous_variant 0.99
rpoC 763594 c.225C>T synonymous_variant 0.97
rpoC 763622 p.Ala85Ser missense_variant 0.95
rpoC 763627 p.Lys86Asn missense_variant 0.94
rpoC 763633 c.264T>C synonymous_variant 0.94
rpoC 763642 c.273G>C synonymous_variant 0.95
rpoC 763660 c.291T>G synonymous_variant 0.95
rpoC 763666 c.297G>C synonymous_variant 0.95
rpoC 763669 c.300C>G synonymous_variant 0.95
rpoC 763699 c.330G>C synonymous_variant 0.9
rpoC 763702 c.333C>G synonymous_variant 0.91
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 0.91
rpoC 763711 c.342G>C synonymous_variant 0.93
rpoC 763714 c.345G>C synonymous_variant 0.93
rpoC 763717 c.348T>C synonymous_variant 0.91
rpoC 763723 c.354G>C synonymous_variant 0.91
rpoC 763732 c.363C>G synonymous_variant 0.91
rpoC 763744 c.375G>C synonymous_variant 0.93
rpoC 763751 p.Ile128Val missense_variant 0.93
rpoC 763765 c.396T>G synonymous_variant 0.91
rpoC 763772 p.Val135Met missense_variant 0.88
rpoC 764308 c.939G>C synonymous_variant 0.71
rpoC 764311 c.942C>G synonymous_variant 0.71
rpoC 764315 p.Ala316Cys missense_variant 0.71
rpoC 764320 c.951C>G synonymous_variant 0.8
rpoC 764326 c.957G>C synonymous_variant 0.8
rpoC 764338 p.Glu323Asp missense_variant 0.83
rpoC 764365 c.996C>T synonymous_variant 0.91
rpoC 764371 c.1002G>C synonymous_variant 0.91
rpoC 764377 c.1008C>G synonymous_variant 0.91
rpoC 764380 c.1011G>C synonymous_variant 0.91
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.91
rpoC 764398 c.1029G>C synonymous_variant 0.92
rpoC 764405 c.1036A>C synonymous_variant 0.83
rpoC 764410 c.1041G>C synonymous_variant 1.0
rpoC 764428 c.1059G>C synonymous_variant 0.6
rpoC 764434 c.1065A>G synonymous_variant 0.5
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.5
rpoC 764441 p.Ile358Leu missense_variant 0.5
rpoC 764446 c.1077T>C synonymous_variant 0.4
rpoC 764449 c.1080G>C synonymous_variant 0.4
rpoC 764452 c.1083T>G synonymous_variant 0.4
rpoC 764455 c.1086G>C synonymous_variant 0.4
rpoC 764458 c.1089G>C synonymous_variant 0.57
rpoC 764461 c.1092A>G synonymous_variant 0.73
rpoC 764470 c.1101C>G synonymous_variant 0.8
rpoC 764497 c.1128A>G synonymous_variant 0.88
rpoC 764500 c.1131C>G synonymous_variant 0.88
rpoC 764503 c.1134G>C synonymous_variant 0.88
rpoC 764521 c.1152T>C synonymous_variant 0.92
rpoC 764527 c.1158C>G synonymous_variant 0.93
rpoC 764533 c.1164C>T synonymous_variant 0.93
rpoC 764536 c.1167G>T synonymous_variant 0.93
rpoC 764539 c.1170C>G synonymous_variant 0.93
rpoC 764548 c.1179G>C synonymous_variant 0.95
rpoC 764551 c.1182G>C synonymous_variant 0.95
rpoC 764560 c.1191T>G synonymous_variant 0.97
rpoC 764561 p.Pro398Ala missense_variant 0.97
rpoC 764566 c.1197C>G synonymous_variant 0.98
rpoC 764575 c.1206T>G synonymous_variant 0.99
rpoC 764581 c.1212T>C synonymous_variant 0.99
rpoC 764582 p.Leu405Met missense_variant 0.99
rpoC 764605 c.1236G>C synonymous_variant 1.0
rpoC 764632 c.1263T>C synonymous_variant 1.0
rpoC 764644 c.1275G>C synonymous_variant 1.0
rpoC 764650 c.1281G>T synonymous_variant 1.0
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 1.0
rpoC 764677 c.1308C>G synonymous_variant 1.0
rpoC 764706 p.Leu446Gln missense_variant 1.0
rpoC 764713 c.1344G>C synonymous_variant 1.0
rpoC 764746 c.1377G>T synonymous_variant 1.0
rpoC 764752 c.1383G>C synonymous_variant 0.98
rpoC 764759 p.Asn464Asp missense_variant 0.98
rpoC 764764 c.1395T>C synonymous_variant 0.98
rpoC 764780 c.1411_1413delAGCinsTCG synonymous_variant 0.97
rpoC 764797 c.1428G>C synonymous_variant 0.96
rpoC 764809 c.1440C>T synonymous_variant 0.69
rpoC 764812 c.1443C>G synonymous_variant 0.9
rpoC 764813 p.Gln482Val missense_variant 0.9
rpoC 764824 c.1455T>C synonymous_variant 0.9
rpoC 764827 c.1458G>C synonymous_variant 0.82
rpoC 764843 p.Ala492Thr missense_variant 0.9
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776182 p.Asp767Asn missense_variant 1.0
mmpS5 778979 c.-74G>T upstream_gene_variant 1.0
rpsL 781670 c.111G>C synonymous_variant 0.5
rpsL 781682 c.123T>C synonymous_variant 0.7
rpsL 781700 c.141G>C synonymous_variant 0.82
rpsL 781706 c.147T>G synonymous_variant 0.82
rpsL 781709 c.150G>C synonymous_variant 0.82
rpsL 781715 c.156T>C synonymous_variant 0.82
rpsL 781718 c.159C>G synonymous_variant 0.82
rpsL 781728 c.169T>C synonymous_variant 0.82
rpsL 781738 p.Gln60Arg missense_variant 0.69
rpsL 781740 c.181_182insCA frameshift_variant 0.69
rpsL 781751 c.192G>C synonymous_variant 0.71
rpsL 781754 c.195G>T synonymous_variant 0.71
rpsL 781760 c.201T>C synonymous_variant 0.67
rpsL 781763 c.204C>G synonymous_variant 0.67
rpsL 781766 c.207C>T synonymous_variant 0.67
rpsL 781768 p.Glu70Val missense_variant 0.67
rpsL 781796 p.Met79Ile missense_variant 0.81
rpsL 781802 c.243G>C synonymous_variant 0.78
rpsL 781814 c.255C>T synonymous_variant 0.82
rpsL 781817 c.258G>T synonymous_variant 0.83
rpsL 781832 c.273T>G synonymous_variant 0.83
rpsL 781859 c.300T>C synonymous_variant 0.85
rpsL 781868 c.309T>C synonymous_variant 0.9
rpsL 781871 c.312G>C synonymous_variant 0.9
rpsL 781884 p.Asn109Gly missense_variant 0.88
rpsL 781890 p.Lys111Gln missense_variant 0.88
rpsL 781898 c.339A>C synonymous_variant 0.88
rpsL 781901 c.342C>T synonymous_variant 0.88
rpsL 781916 c.357T>G synonymous_variant 0.81
rpsL 781929 p.Gly124Lys missense_variant 0.6
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.5
rplC 800612 c.-197A>G upstream_gene_variant 0.55
rplC 800618 c.-191T>G upstream_gene_variant 0.6
rplC 800630 c.-179G>C upstream_gene_variant 0.6
rplC 800632 c.-177_-176delATinsTC upstream_gene_variant 0.6
rplC 800645 c.-164C>G upstream_gene_variant 0.6
rplC 800648 c.-161A>G upstream_gene_variant 0.6
rplC 800654 c.-155T>C upstream_gene_variant 0.67
rplC 800667 c.-142_-140delTCGinsAGC upstream_gene_variant 0.55
rplC 800672 c.-137G>C upstream_gene_variant 0.55
rplC 800693 c.-116A>C upstream_gene_variant 0.6
rplC 800702 c.-107G>C upstream_gene_variant 0.44
rplC 800703 c.-106T>C upstream_gene_variant 0.5
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.79
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.87
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.95
rrs 1472107 n.262A>G non_coding_transcript_exon_variant 0.95
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.96
rrs 1472123 n.278A>G non_coding_transcript_exon_variant 0.97
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.97
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.98
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.98
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.98
rrs 1472278 n.433C>T non_coding_transcript_exon_variant 0.99
rrs 1472279 n.434T>C non_coding_transcript_exon_variant 0.99
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 1.0
rrs 1472290 n.445C>T non_coding_transcript_exon_variant 0.99
rrs 1472297 n.453_454delGT non_coding_transcript_exon_variant 1.0
rrs 1472301 n.457_461delGGGTT non_coding_transcript_exon_variant 1.0
rrs 1472308 n.464delC non_coding_transcript_exon_variant 1.0
rrs 1472314 n.469A>G non_coding_transcript_exon_variant 1.0
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 1.0
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.98
rrs 1472345 n.500A>G non_coding_transcript_exon_variant 0.99
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.82
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.81
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.8
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.25
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.72
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.94
rrs 1472495 n.650C>T non_coding_transcript_exon_variant 0.94
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.94
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.96
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.98
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.98
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.98
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.98
rrs 1472582 n.737G>A non_coding_transcript_exon_variant 0.98
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.98
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.99
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.99
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.99
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.99
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.99
rrs 1472673 n.828T>A non_coding_transcript_exon_variant 0.99
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.99
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.99
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.99
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.99
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.99
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.99
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.99
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.99
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 1.0
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.99
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.99
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.99
rrs 1472840 n.995A>C non_coding_transcript_exon_variant 0.99
rrs 1472846 n.1001C>A non_coding_transcript_exon_variant 0.94
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.92
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.92
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.92
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.79
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.79
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.79
rrs 1472861 n.1016G>T non_coding_transcript_exon_variant 0.79
rrs 1472866 n.1023dupT non_coding_transcript_exon_variant 0.79
rrs 1472874 n.1029C>T non_coding_transcript_exon_variant 0.79
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 0.79
rrs 1472879 n.1034T>C non_coding_transcript_exon_variant 0.77
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.81
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.97
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.98
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.98
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.98
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.98
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.99
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.99
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.99
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.99
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.99
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.99
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.99
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.99
rrs 1473099 n.1254T>G non_coding_transcript_exon_variant 0.99
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.99
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.99
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.99
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.99
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 1.0
rrs 1473129 n.1284C>T non_coding_transcript_exon_variant 1.0
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 1.0
rrs 1473165 n.1320C>T non_coding_transcript_exon_variant 1.0
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 1.0
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 1.0
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.98
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.98
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.96
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.95
rrs 1473294 n.1449A>G non_coding_transcript_exon_variant 0.94
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.96
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.96
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.96
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.96
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.4
rrl 1473768 n.111A>G non_coding_transcript_exon_variant 0.82
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.91
rrl 1473793 n.136G>C non_coding_transcript_exon_variant 0.94
rrl 1473794 n.137A>T non_coding_transcript_exon_variant 0.94
rrl 1473797 n.140G>T non_coding_transcript_exon_variant 0.94
rrl 1473801 n.144T>A non_coding_transcript_exon_variant 0.94
rrl 1473802 n.145C>G non_coding_transcript_exon_variant 0.94
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.95
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.96
rrl 1473833 n.176_177insT non_coding_transcript_exon_variant 0.96
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.98
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 0.98
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 1.0
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0
rrl 1473887 n.230_231insA non_coding_transcript_exon_variant 1.0
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 1.0
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 1.0
rrl 1473922 n.265A>T non_coding_transcript_exon_variant 0.96
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.96
rrl 1473934 n.277G>T non_coding_transcript_exon_variant 0.67
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.67
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.93
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.93
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.91
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.93
rrl 1474283 n.626A>G non_coding_transcript_exon_variant 0.93
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.93
rrl 1474310 n.655dupG non_coding_transcript_exon_variant 0.93
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.85
rrl 1474450 n.793T>G non_coding_transcript_exon_variant 0.83
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.94
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.98
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.98
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.98
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.98
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.98
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.99
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.99
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.99
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.99
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.99
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.99
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.99
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.99
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.99
rrl 1474708 n.1053_1054delTG non_coding_transcript_exon_variant 0.99
rrl 1474713 n.1056_1057insAA non_coding_transcript_exon_variant 1.0
rrl 1474716 n.1059A>G non_coding_transcript_exon_variant 0.99
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.99
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 1.0
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 1.0
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.99
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.99
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 0.99
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.99
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.99
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.99
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.99
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.99
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.99
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 0.99
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.98
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.98
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.98
rrl 1474936 n.1279C>T non_coding_transcript_exon_variant 0.83
rrl 1474938 n.1281G>A non_coding_transcript_exon_variant 0.78
rrl 1474946 n.1289C>T non_coding_transcript_exon_variant 0.71
rrl 1474948 n.1291C>T non_coding_transcript_exon_variant 0.6
rrl 1475060 n.1403_1404insAT non_coding_transcript_exon_variant 0.62
rrl 1475063 n.1406A>C non_coding_transcript_exon_variant 0.62
rrl 1475065 n.1409_1411delCAA non_coding_transcript_exon_variant 0.62
rrl 1475080 n.1425_1426delCC non_coding_transcript_exon_variant 0.71
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.71
rrl 1475091 n.1434G>A non_coding_transcript_exon_variant 0.71
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.75
rrl 1475108 n.1451C>T non_coding_transcript_exon_variant 0.75
rrl 1475111 n.1454G>A non_coding_transcript_exon_variant 0.75
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.75
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.75
rrl 1475119 n.1462C>T non_coding_transcript_exon_variant 0.75
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.8
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.82
rrl 1475173 n.1516A>T non_coding_transcript_exon_variant 0.75
rrl 1475175 n.1518G>C non_coding_transcript_exon_variant 0.75
rrl 1475508 n.1851A>T non_coding_transcript_exon_variant 0.75
rrl 1475517 n.1860C>T non_coding_transcript_exon_variant 0.75
rrl 1475518 n.1861A>G non_coding_transcript_exon_variant 0.75
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.75
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.67
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.67
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 1.0
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 1.0
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 1.0
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 1.0
rrl 1475562 n.1905C>T non_coding_transcript_exon_variant 1.0
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.64
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.82
rrl 1475655 n.1998T>G non_coding_transcript_exon_variant 0.82
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.83
rrl 1475696 n.2039T>A non_coding_transcript_exon_variant 0.83
rrl 1475697 n.2040C>A non_coding_transcript_exon_variant 0.83
rrl 1475702 n.2045G>T non_coding_transcript_exon_variant 0.85
rrl 1475703 n.2046A>T non_coding_transcript_exon_variant 0.86
rrl 1475740 n.2083G>C non_coding_transcript_exon_variant 0.96
rrl 1475747 n.2090A>G non_coding_transcript_exon_variant 0.97
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.97
rrl 1475759 n.2103_2107delCCGCA non_coding_transcript_exon_variant 1.0
rrl 1475767 n.2110G>T non_coding_transcript_exon_variant 1.0
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 1.0
rrl 1475780 n.2123A>T non_coding_transcript_exon_variant 1.0
rrl 1475781 n.2124T>C non_coding_transcript_exon_variant 1.0
rrl 1475788 n.2131C>G non_coding_transcript_exon_variant 1.0
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 1.0
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 1.0
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 1.0
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 1.0
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.99
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.99
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.99
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.99
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.99
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.98
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.98
rrl 1476022 n.2366delC non_coding_transcript_exon_variant 0.67
rrl 1476049 n.2392C>G non_coding_transcript_exon_variant 0.88
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.99
rrl 1476081 n.2424A>T non_coding_transcript_exon_variant 0.99
rrl 1476082 n.2425T>C non_coding_transcript_exon_variant 0.99
rrl 1476088 n.2431A>T non_coding_transcript_exon_variant 0.99
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.99
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.99
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.99
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 0.99
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.99
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.99
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.99
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.99
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.99
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.99
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.99
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.99
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.99
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.99
rrl 1476251 n.2594T>A non_coding_transcript_exon_variant 0.98
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.98
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.98
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.98
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.98
rrl 1476287 n.2631_2639delTCCGGCACC non_coding_transcript_exon_variant 0.98
rrl 1476301 n.2644_2645insCGGTGGCTT non_coding_transcript_exon_variant 0.97
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.97
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.96
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.96
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.99
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 0.99
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.99
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.99
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.99
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.99
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.99
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.99
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.99
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.99
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.99
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.99
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.98
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.99
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.99
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.99
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.95
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.95
rrl 1476586 n.2929C>T non_coding_transcript_exon_variant 0.95
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.95
rrl 1476596 n.2939C>T non_coding_transcript_exon_variant 0.95
rrl 1476601 n.2944G>A non_coding_transcript_exon_variant 0.95
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.95
rrl 1476613 n.2956G>A non_coding_transcript_exon_variant 0.95
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.95
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.95
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.95
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.95
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.95
rrl 1476631 n.2974G>T non_coding_transcript_exon_variant 0.95
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.67
rpsA 1833635 p.Tyr32His missense_variant 0.77
rpsA 1833643 c.102C>T synonymous_variant 0.8
rpsA 1833646 c.105T>C synonymous_variant 0.86
rpsA 1833661 c.120A>G synonymous_variant 0.89
rpsA 1833664 c.123C>T synonymous_variant 0.89
rpsA 1833665 p.Thr42Val missense_variant 0.89
rpsA 1833676 c.135A>G synonymous_variant 0.91
rpsA 1833679 c.138G>C synonymous_variant 0.92
rpsA 1833694 c.153G>C synonymous_variant 0.96
rpsA 1833697 c.156C>G synonymous_variant 0.96
rpsA 1833721 c.180A>G synonymous_variant 0.96
rpsA 1833727 c.186G>C synonymous_variant 0.96
rpsA 1833734 p.Ala65Ser missense_variant 0.96
rpsA 1833742 c.201A>G synonymous_variant 0.97
rpsA 1833748 c.207C>G synonymous_variant 0.97
rpsA 1833781 c.240T>C synonymous_variant 0.99
rpsA 1833790 c.249T>C synonymous_variant 0.99
rpsA 1833796 p.Glu85Asp missense_variant 0.99
rpsA 1833802 c.261A>G synonymous_variant 1.0
rpsA 1833811 c.270G>C synonymous_variant 1.0
rpsA 1833815 p.Thr92Gln missense_variant 1.0
rpsA 1833829 c.288A>G synonymous_variant 1.0
rpsA 1833832 c.291G>A synonymous_variant 1.0
rpsA 1833838 c.297G>C synonymous_variant 1.0
rpsA 1833841 c.300C>G synonymous_variant 1.0
rpsA 1833847 c.306C>G synonymous_variant 1.0
rpsA 1833856 c.315A>G synonymous_variant 1.0
rpsA 1833859 c.318C>T synonymous_variant 1.0
rpsA 1833874 c.333T>C synonymous_variant 1.0
rpsA 1833893 p.Ala118Gln missense_variant 0.98
rpsA 1833896 p.Leu119Ile missense_variant 0.97
rpsA 1833905 p.Lys122Asp missense_variant 0.97
rpsA 1833912 p.Glu124Gly missense_variant 0.97
rpsA 1833915 p.Ala125Val missense_variant 0.97
rpsA 1833921 p.Lys127Thr missense_variant 0.96
rpsA 1833928 c.387G>C synonymous_variant 0.97
rpsA 1833949 c.408T>C synonymous_variant 0.98
rpsA 1833955 c.414G>C synonymous_variant 0.97
rpsA 1833970 c.429G>C synonymous_variant 0.98
rpsA 1833976 c.435C>T synonymous_variant 0.98
rpsA 1833979 c.438T>C synonymous_variant 0.98
rpsA 1833991 c.450C>G synonymous_variant 0.98
rpsA 1834000 c.459G>C synonymous_variant 0.98
rpsA 1834009 c.468C>T synonymous_variant 0.97
rpsA 1834012 c.471G>C synonymous_variant 0.98
rpsA 1834015 c.474G>C synonymous_variant 0.98
rpsA 1834024 c.483G>C synonymous_variant 0.99
rpsA 1834030 c.489C>G synonymous_variant 0.99
rpsA 1834034 p.Ile165Val missense_variant 0.98
rpsA 1834069 c.528G>C synonymous_variant 0.98
rpsA 1834096 c.555G>C synonymous_variant 0.94
rpsA 1834099 c.558C>T synonymous_variant 0.94
rpsA 1834102 c.561T>C synonymous_variant 0.94
rpsA 1834108 c.567C>G synonymous_variant 0.93
rpsA 1834114 c.573G>C synonymous_variant 0.93
rpsA 1834210 c.669C>T synonymous_variant 0.92
rpsA 1834222 c.681T>C synonymous_variant 0.94
rpsA 1834228 c.687C>T synonymous_variant 0.94
rpsA 1834231 c.690T>A synonymous_variant 0.95
rpsA 1834234 c.693G>C synonymous_variant 0.95
rpsA 1834249 c.708T>C synonymous_variant 0.96
rpsA 1834261 c.720A>G synonymous_variant 0.96
rpsA 1834264 c.723G>C synonymous_variant 0.96
rpsA 1834294 c.753G>C synonymous_variant 0.96
rpsA 1834298 p.Gln253Glu missense_variant 0.96
rpsA 1834303 c.762T>G synonymous_variant 0.96
rpsA 1834306 c.765T>C synonymous_variant 0.96
rpsA 1834307 p.Asp256Gln missense_variant 0.96
rpsA 1834348 c.807T>C synonymous_variant 0.98
rpsA 1834354 c.813G>T synonymous_variant 0.96
rpsA 1834357 c.816T>C synonymous_variant 0.96
rpsA 1834360 c.819G>C synonymous_variant 0.95
rpsA 1834361 c.820T>C synonymous_variant 0.96
rpsA 1834366 c.825A>G synonymous_variant 0.95
rpsA 1834369 c.828C>G synonymous_variant 0.95
rpsA 1834378 c.837T>C synonymous_variant 0.96
rpsA 1834384 c.843A>G synonymous_variant 0.96
rpsA 1834395 p.Arg285Gln missense_variant 0.96
rpsA 1834411 c.870T>C synonymous_variant 0.96
rpsA 1834417 c.876G>C synonymous_variant 0.96
rpsA 1834423 c.882G>C synonymous_variant 0.96
rpsA 1834427 p.Ile296Val missense_variant 0.96
rpsA 1834451 c.910T>C synonymous_variant 0.97
rpsA 1834456 c.915T>G synonymous_variant 0.96
rpsA 1834468 c.927A>G synonymous_variant 0.95
rpsA 1834474 c.933C>G synonymous_variant 0.93
rpsA 1834483 p.Glu314Asp missense_variant 0.94
rpsA 1834486 p.Glu315Asp missense_variant 0.94
rpsA 1834489 c.948T>C synonymous_variant 0.95
rpsA 1834528 c.987T>C synonymous_variant 0.93
rpsA 1834534 c.993C>G synonymous_variant 0.91
rpsA 1834538 p.Val333Leu missense_variant 0.91
rpsA 1834546 p.Asp335Glu missense_variant 0.89
rpsA 1834552 c.1011G>C synonymous_variant 0.86
rpsA 1834555 c.1014T>C synonymous_variant 0.79
rpsA 1834556 p.Ala339Thr missense_variant 0.79
rpsA 1834564 c.1024_1028delGACGA frameshift_variant 0.79
rpsA 1834572 p.Ala344Val missense_variant 0.79
rpsA 1834606 c.1065C>T synonymous_variant 0.88
rpsA 1834612 c.1071G>C synonymous_variant 0.87
rpsA 1834619 c.1078T>C synonymous_variant 0.75
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155410 c.702G>C synonymous_variant 0.67
katG 2155416 c.696G>C synonymous_variant 0.6
katG 2155422 c.690G>C synonymous_variant 0.67
katG 2155434 c.678G>T synonymous_variant 0.67
katG 2155443 c.669G>C synonymous_variant 0.67
katG 2155467 c.645T>C synonymous_variant 0.67
katG 2155470 c.642G>C synonymous_variant 0.67
katG 2155475 p.Lys213Glu missense_variant 0.6
katG 2155480 p.Ser211Thr missense_variant 0.6
katG 2155485 c.627T>C synonymous_variant 0.6
katG 2155490 p.Glu208Lys missense_variant 0.6
katG 2155491 c.621T>C synonymous_variant 0.6
katG 2155677 c.435C>G synonymous_variant 0.91
katG 2155680 c.432G>C synonymous_variant 0.91
katG 2155689 c.421_423delTTGinsCTC synonymous_variant 0.91
katG 2155696 p.Ala139Gly missense_variant 0.93
katG 2155716 c.396T>C synonymous_variant 1.0
katG 2155722 c.390G>C synonymous_variant 1.0
katG 2155735 p.Met126Gln missense_variant 1.0
katG 2155741 p.Gly124Thr missense_variant 1.0
katG 2155743 c.369G>C synonymous_variant 1.0
katG 2155758 c.354C>T synonymous_variant 1.0
katG 2155765 p.His116Ala missense_variant 1.0
katG 2155768 p.Ile115Thr missense_variant 1.0
katG 2155785 p.Ala109Ser missense_variant 1.0
katG 2155794 c.318G>C synonymous_variant 1.0
katG 2155806 p.Phe102Met missense_variant 1.0
katG 2155815 c.297G>C synonymous_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3877638 c.870T>G synonymous_variant 0.33
rpoA 3877656 c.852T>C synonymous_variant 0.75
rpoA 3877667 p.Ser281Ala missense_variant 0.75
rpoA 3877668 c.840A>G synonymous_variant 0.75
rpoA 3877672 p.Thr279Ser missense_variant 0.75
rpoA 3877677 p.Ala277Gly missense_variant 0.75
rpoA 3877683 c.825G>C synonymous_variant 0.75
rpoA 3877686 c.822A>G synonymous_variant 0.75
rpoA 3877689 c.819C>T synonymous_variant 0.75
rpoA 3877696 p.Thr271Ser missense_variant 0.86
rpoA 3877701 p.Val269Ile missense_variant 0.86
rpoA 3877704 c.804G>C synonymous_variant 0.86
rpoA 3877737 c.771G>C synonymous_variant 0.8
rpoA 3877743 p.Asp255Glu missense_variant 0.77
rpoA 3877746 c.762G>C synonymous_variant 0.77
rpoA 3877752 p.Asp252Glu missense_variant 0.83
rpoA 3877764 c.744C>G synonymous_variant 0.71
rpoA 3877836 c.672A>G synonymous_variant 0.57
rpoA 3877839 c.669G>C synonymous_variant 0.57
rpoA 3877842 c.666A>C synonymous_variant 0.75
rpoA 3877856 c.652T>C synonymous_variant 0.87
rpoA 3877866 c.642G>C synonymous_variant 0.9
rpoA 3877875 c.633T>C synonymous_variant 0.87
rpoA 3877878 c.630G>C synonymous_variant 0.87
rpoA 3877881 c.627G>C synonymous_variant 0.87
rpoA 3877886 p.Leu208Met missense_variant 0.87
rpoA 3877893 c.615C>T synonymous_variant 0.87
rpoA 3877900 p.Ser203Ala missense_variant 0.87
rpoA 3877902 p.Ile202Met missense_variant 0.87
rpoA 3877905 c.603A>G synonymous_variant 0.87
rpoA 3877908 c.600T>C synonymous_variant 0.87
rpoA 3877920 c.588G>C synonymous_variant 0.87
rpoA 3877926 p.Leu194Val missense_variant 0.87
rpoA 3877932 c.576G>C synonymous_variant 0.91
rpoA 3877962 c.546G>A synonymous_variant 0.94
rpoA 3878217 c.291A>G synonymous_variant 0.33
rpoA 3878226 p.Thr94Val missense_variant 0.33
rpoA 3878241 p.Glu89His missense_variant 0.33
rpoA 3878253 c.255G>C synonymous_variant 0.4
rpoA 3878256 c.252G>C synonymous_variant 0.4
rpoA 3878264 p.Ser82Gly missense_variant 0.4
rpoA 3878270 p.Leu80Ile missense_variant 0.4
rpoA 3878271 c.237T>C synonymous_variant 0.4
rpoA 3878274 c.234G>C synonymous_variant 0.4
rpoA 3878292 c.216T>C synonymous_variant 0.4
rpoA 3878295 c.213A>G synonymous_variant 0.4
rpoA 3878298 c.210A>G synonymous_variant 0.5
rpoA 3878310 c.198G>C synonymous_variant 0.67
rpoA 3878318 p.Thr64Ser missense_variant 0.67
rpoA 3878322 c.186A>G synonymous_variant 0.67
clpC1 4038499 p.Ser736Gly missense_variant 0.67
clpC1 4038515 p.Met730Ile missense_variant 0.9
clpC1 4038519 p.Arg729Gln missense_variant 0.9
clpC1 4038523 p.Ile728Val missense_variant 0.9
clpC1 4038531 c.2173delG frameshift_variant 0.9
clpC1 4038536 c.2168_2169insG frameshift_variant 0.9
clpC1 4038539 c.2166G>C synonymous_variant 0.9
clpC1 4038545 p.His720Pro missense_variant 0.9
clpC1 4038558 p.Ile716Thr missense_variant 0.9
clpC1 4038568 p.Ile713Val missense_variant 0.9
clpC1 4038569 c.2136C>G synonymous_variant 0.9
clpC1 4038587 c.2118C>G synonymous_variant 1.0
clpC1 4038596 p.Lys703Gln missense_variant 1.0
clpC1 4038826 p.Ile627Val missense_variant 1.0
clpC1 4038860 c.1845G>C synonymous_variant 1.0
clpC1 4038878 c.1827A>G synonymous_variant 0.94
clpC1 4038881 c.1824C>T synonymous_variant 0.94
clpC1 4038890 p.Glu605Asp missense_variant 0.94
clpC1 4038905 c.1800A>G synonymous_variant 0.89
clpC1 4038911 c.1794G>C synonymous_variant 0.88
clpC1 4038914 p.Ala597Ser missense_variant 0.88
clpC1 4038923 c.1782A>G synonymous_variant 0.88
clpC1 4038933 p.Ala591Val missense_variant 0.86
clpC1 4039418 c.1287C>G synonymous_variant 0.4
clpC1 4039430 c.1275T>C synonymous_variant 0.73
clpC1 4039442 c.1263A>G synonymous_variant 0.73
clpC1 4039448 c.1257A>G synonymous_variant 0.73
clpC1 4039454 c.1251A>T synonymous_variant 0.79
clpC1 4039457 c.1248C>G synonymous_variant 0.79
clpC1 4039463 c.1242C>G synonymous_variant 0.79
clpC1 4039466 c.1239T>C synonymous_variant 0.85
clpC1 4039469 c.1236T>C synonymous_variant 0.85
clpC1 4039472 c.1233G>C synonymous_variant 0.79
clpC1 4039477 p.Met410Leu missense_variant 0.73
clpC1 4039478 c.1227G>A synonymous_variant 0.73
clpC1 4039481 c.1224T>G synonymous_variant 0.69
clpC1 4039484 c.1221T>C synonymous_variant 0.74
clpC1 4039499 c.1206G>C synonymous_variant 0.85
clpC1 4039524 p.Phe394His missense_variant 0.88
clpC1 4039549 p.Ala386Ser missense_variant 0.87
clpC1 4039552 p.Leu385Met missense_variant 0.87
clpC1 4039554 p.Thr384Asn missense_variant 0.87
clpC1 4039556 p.Ala383Val missense_variant 0.87
clpC1 4039559 c.1146C>G synonymous_variant 0.87
clpC1 4039563 p.Ala381Gly missense_variant 0.88
clpC1 4039565 c.1140G>C synonymous_variant 0.88
clpC1 4039570 p.Met379Leu missense_variant 0.89
clpC1 4039577 c.1128T>C synonymous_variant 0.89
clpC1 4039588 p.Ser373Thr missense_variant 0.9
clpC1 4039589 c.1116G>C synonymous_variant 0.91
clpC1 4039610 c.1095G>C synonymous_variant 0.95
clpC1 4039616 c.1089G>C synonymous_variant 0.95
clpC1 4039622 c.1083C>G synonymous_variant 0.95
clpC1 4039642 p.Thr355Ala missense_variant 0.96
clpC1 4039647 p.Glu353Pro missense_variant 0.95
clpC1 4039649 p.Val352Ile missense_variant 0.95
clpC1 4039661 p.Gly348Ala missense_variant 0.95
clpC1 4039670 p.Val345Ile missense_variant 0.95
clpC1 4039685 c.1020C>G synonymous_variant 0.96
clpC1 4039691 c.1014G>C synonymous_variant 0.95
clpC1 4039694 c.1011G>C synonymous_variant 0.94
clpC1 4039697 c.1008C>T synonymous_variant 0.94
clpC1 4039714 p.Tyr331His missense_variant 0.95
clpC1 4039724 c.981A>G synonymous_variant 0.95
clpC1 4039733 c.972G>C synonymous_variant 0.95
clpC1 4039736 c.969C>G synonymous_variant 0.92
clpC1 4039739 c.966C>G synonymous_variant 0.92
clpC1 4039742 c.963C>T synonymous_variant 0.92
clpC1 4039751 c.954A>G synonymous_variant 0.92
clpC1 4039757 c.948A>G synonymous_variant 0.92
clpC1 4039760 c.945T>C synonymous_variant 0.92
clpC1 4039763 c.942C>G synonymous_variant 0.92
clpC1 4039766 c.939T>G synonymous_variant 0.92
clpC1 4039769 c.936C>G synonymous_variant 0.92
clpC1 4039773 p.Lys311Met missense_variant 0.93
clpC1 4039778 c.927A>G synonymous_variant 0.93
clpC1 4039781 c.924G>C synonymous_variant 0.94
clpC1 4039802 c.903G>C synonymous_variant 0.95
clpC1 4039817 c.888A>T synonymous_variant 0.94
clpC1 4039820 c.885T>C synonymous_variant 0.94
clpC1 4039823 c.882T>C synonymous_variant 0.95
clpC1 4039831 c.874T>C synonymous_variant 0.95
clpC1 4039838 p.Leu289Ile missense_variant 0.94
clpC1 4039850 c.855T>C synonymous_variant 0.95
clpC1 4039865 c.840T>C synonymous_variant 0.96
clpC1 4039875 p.Asn277Arg missense_variant 0.96
clpC1 4039886 c.819C>G synonymous_variant 0.96
clpC1 4039904 c.801A>G synonymous_variant 0.95
clpC1 4039925 c.780C>T synonymous_variant 0.94
clpC1 4039931 c.774T>C synonymous_variant 0.93
clpC1 4039934 c.771G>C synonymous_variant 0.93
clpC1 4039946 c.759A>G synonymous_variant 0.94
clpC1 4039949 c.756G>C synonymous_variant 0.93
clpC1 4039952 c.753T>C synonymous_variant 0.93
clpC1 4039955 c.750G>C synonymous_variant 0.93
clpC1 4039958 c.747G>C synonymous_variant 0.93
clpC1 4039964 c.741C>G synonymous_variant 0.94
clpC1 4039994 p.Glu237Asp missense_variant 0.94
clpC1 4040001 p.His235Arg missense_variant 0.93
clpC1 4040010 p.Ala232Asp missense_variant 0.93
clpC1 4040012 p.Gln231Ala missense_variant 0.93
clpC1 4040018 c.687G>C synonymous_variant 0.93
clpC1 4040021 c.684A>C synonymous_variant 0.93
clpC1 4040024 c.681A>G synonymous_variant 0.93
clpC1 4040033 c.672G>C synonymous_variant 0.94
clpC1 4040036 c.669C>G synonymous_variant 0.94
clpC1 4040057 c.648C>T synonymous_variant 0.93
clpC1 4040063 c.642G>C synonymous_variant 0.92
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.87
clpC1 4040093 c.612C>G synonymous_variant 0.85
clpC1 4040105 c.600C>G synonymous_variant 0.85
clpC1 4040108 c.597G>C synonymous_variant 0.85
clpC1 4040117 c.588A>G synonymous_variant 0.79
clpC1 4040129 p.Gly192Met missense_variant 0.75
clpC1 4040144 c.561G>C synonymous_variant 0.7
clpC1 4040147 c.558A>G synonymous_variant 0.57
clpC1 4040255 p.Ala150Pro missense_variant 0.67
clpC1 4040267 c.438A>G synonymous_variant 0.86
clpC1 4040273 c.432T>A synonymous_variant 0.84
clpC1 4040278 p.Ser143Ala missense_variant 0.88
clpC1 4040291 c.414G>C synonymous_variant 0.92
clpC1 4040300 c.405C>G synonymous_variant 0.93
clpC1 4040306 p.Arg133Ser missense_variant 0.91
clpC1 4040311 p.Thr132Ser missense_variant 0.91
clpC1 4040315 p.Glu130Asp missense_variant 0.91
clpC1 4040354 c.351A>G synonymous_variant 0.89
clpC1 4040363 c.342A>C synonymous_variant 0.89
clpC1 4040369 c.336C>G synonymous_variant 0.89
clpC1 4040375 c.330G>C synonymous_variant 0.89
clpC1 4040380 c.325T>C synonymous_variant 0.87
clpC1 4040381 c.324T>C synonymous_variant 0.89
clpC1 4040387 c.318A>G synonymous_variant 0.89
clpC1 4040393 c.312G>C synonymous_variant 0.9
clpC1 4040403 p.Asn101Ser missense_variant 0.89
clpC1 4040411 c.294T>G synonymous_variant 0.7
embA 4243460 c.228C>T synonymous_variant 1.0
aftB 4267647 p.Asp397Gly missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 1.0