TB-Profiler result

Run: 2cb3c75e-c537-41fc-9889-83852660c29e
Summary

Run ID: 2cb3c75e-c537-41fc-9889-83852660c29e

Sample name:

Date: 08-01-2023 22:45:22

Number of reads: 266524

Percentage reads mapped: 7.81

Median coverage: 5

Strain: lineage2

Spoligotype:

Drug-resistance: RR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage2 East-Asian RD105 0.96
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB p.Ser441Ala Assoc w R - interim
isoniazid
ethambutol embB p.Glu405Asp Uncertain significance
pyrazinamide
moxifloxacin
levofloxacin
bedaquiline
delamanid
pretomanid
linezolid
streptomycin
amikacin rrs n.1402C>A Uncertain significance
n.1484G>T Assoc w R - interim
kanamycin rrs n.1402C>A Uncertain significance
n.1484G>T Assoc w R
capreomycin rrs n.1402C>A Uncertain significance
n.1484G>T Assoc w R
clofazimine
ethionamide
para-aminosalicylic_acid
cycloserine
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpoB 761127 p.Ser441Ala missense_variant 0.69 rifampicin Assoc w R - interim
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
aminoglycosides Uncertain significance
amikacin Uncertain significance
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.96 kanamycin Assoc w R
capreomycin Assoc w R
aminoglycosides Uncertain significance
amikacin Assoc w R - interim
embB 4247728 p.Glu405Asp missense_variant 0.15 ethambutol Uncertain significance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 5079 c.-161G>T upstream_gene_variant 0.12 fluoroquinolones
moxifloxacin
levofloxacin
ciprofloxacin
ofloxacin
rpoB 760085 p.Phe93Leu missense_variant 0.2 rifampicin Uncertain significance
rpoB 760946 c.1140A>G synonymous_variant 0.5 rifampicin
rpoB 760953 p.Ile383Val missense_variant 0.5 rifampicin
rpoB 760958 c.1152G>C synonymous_variant 0.5 rifampicin
rpoB 760959 p.Val385Thr missense_variant 0.5 rifampicin
rpoB 760965 p.Met387Leu missense_variant 0.46 rifampicin
rpoB 760973 c.1167G>C synonymous_variant 0.68 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.74 rifampicin
rpoB 760985 c.1179G>C synonymous_variant 0.74 rifampicin
rpoB 760991 c.1185G>C synonymous_variant 0.74 rifampicin
rpoB 760997 c.1191G>C synonymous_variant 0.81 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 0.75 rifampicin
rpoB 761013 p.Val403Ile missense_variant 0.78 rifampicin
rpoB 761027 c.1221A>C synonymous_variant 0.83 rifampicin
rpoB 761036 c.1230G>C synonymous_variant 0.85 rifampicin
rpoB 761037 c.1231T>C synonymous_variant 0.85 rifampicin
rpoB 761046 p.Ile414Val missense_variant 0.85 rifampicin
rpoB 761051 c.1245G>A synonymous_variant 0.85 rifampicin
rpoB 761057 c.1251G>C synonymous_variant 0.85 rifampicin
rpoB 761088 c.1282_1284delAGCinsTCG synonymous_variant 0.78 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.78 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.78 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 0.67 rifampicin
rpoB 761133 c.1327_1329delTTGinsCTC synonymous_variant 0.67 rifampicin
rpoB 761150 c.1344A>C synonymous_variant 0.73 rifampicin
rpoB 761980 p.Tyr725Phe missense_variant 0.23 rifampicin
rpoB 761998 c.2193_2195delGTC disruptive_inframe_deletion 0.23 rifampicin
rpoB 762004 p.Asn733Ser missense_variant 0.23 rifampicin
rpoB 762014 c.2208C>G synonymous_variant 0.23 rifampicin
rpoB 762015 p.Glu737Lys missense_variant 0.23 rifampicin
rpoB 762020 p.Glu738Asp missense_variant 0.23 rifampicin
rpoB 762026 c.2220G>C synonymous_variant 0.23 rifampicin
rpoB 762030 p.Thr742Ser missense_variant 0.25 rifampicin
rpoB 762051 p.His749Tyr missense_variant 0.42 rifampicin Uncertain significance
rpoB 762057 p.Ile751Val missense_variant 0.36 rifampicin Uncertain significance
rpoB 762062 c.2256T>C synonymous_variant 0.42 rifampicin
rpoB 762065 c.2259T>C synonymous_variant 0.42 rifampicin
rpoB 762080 c.2274G>C synonymous_variant 0.42 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 0.42 rifampicin
rpoB 762084 p.Ala760Lys missense_variant 0.42 rifampicin
rpoC 762842 c.-528G>C upstream_gene_variant 0.71 rifampicin
rpoB 762858 p.Thr1018Ser missense_variant 0.83 rifampicin
rpoC 762863 c.-507T>C upstream_gene_variant 0.86 rifampicin
rpoB 762879 p.Met1025Leu missense_variant 0.82 rifampicin
rpoC 762896 c.-474G>C upstream_gene_variant 0.87 rifampicin
rpoC 762899 c.-471G>C upstream_gene_variant 0.91 rifampicin
rpoC 762917 c.-453C>G upstream_gene_variant 0.91 rifampicin
rpoC 762920 c.-450C>T upstream_gene_variant 0.89 rifampicin
rpoC 762923 c.-447C>G upstream_gene_variant 0.86 rifampicin
rpoC 762926 c.-444C>G upstream_gene_variant 0.86 rifampicin
rpoC 762929 c.-441G>C upstream_gene_variant 0.86 rifampicin
rpoC 762959 c.-411G>C upstream_gene_variant 0.86 rifampicin
rpoC 762962 c.-408C>T upstream_gene_variant 0.85 rifampicin
rpoC 762980 c.-390T>C upstream_gene_variant 0.88 rifampicin
rpoC 762983 c.-387C>T upstream_gene_variant 0.89 rifampicin
rpoC 762989 c.-381G>A upstream_gene_variant 0.88 rifampicin
rpoC 762995 c.-375G>C upstream_gene_variant 0.86 rifampicin
rpoB 763005 p.Cys1067Val missense_variant 0.76 rifampicin
rpoB 763014 p.Met1070Leu missense_variant 0.73 rifampicin
rpoB 763017 p.Gln1071Glu missense_variant 0.73 rifampicin
rpoC 763028 c.-342T>C upstream_gene_variant 0.79 rifampicin
rpoC 763031 c.-339T>C upstream_gene_variant 1.0 rifampicin
rpoB 763038 p.Thr1078Ala missense_variant 0.8 rifampicin
rpoC 763052 c.-318G>C upstream_gene_variant 0.79 rifampicin
rpoC 763053 c.-317_-315delTTGinsCTC upstream_gene_variant 0.76 rifampicin
rpoC 763058 c.-312C>G upstream_gene_variant 0.78 rifampicin
rpoC 763070 c.-300T>C upstream_gene_variant 0.82 rifampicin
rpoB 763075 p.Thr1090Ile missense_variant 0.82 rifampicin
rpoB 763077 p.Val1091Leu missense_variant 0.84 rifampicin
rpoC 763103 c.-267G>C upstream_gene_variant 0.74 rifampicin
rpoC 763115 c.-255T>C upstream_gene_variant 0.58 rifampicin
rpoB 763126 p.Pro1107Gln missense_variant 0.56 rifampicin
rpoC 763133 c.-237G>C upstream_gene_variant 0.56 rifampicin
rpoC 763148 c.-222G>C upstream_gene_variant 0.59 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 0.3 rifampicin
rpoC 763447 c.78C>T synonymous_variant 0.45 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.76 rifampicin
rpoC 763462 c.93G>C synonymous_variant 0.81 rifampicin
rpoC 763486 c.117T>G synonymous_variant 0.81 rifampicin
rpoC 763492 c.123G>C synonymous_variant 0.81 rifampicin
rpoC 763507 c.138G>C synonymous_variant 0.77 rifampicin
rpoC 763511 p.Cys48Gly missense_variant 0.77 rifampicin
rpoC 763517 p.Lys50Gln missense_variant 0.77 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.77 rifampicin
rpoC 763531 c.162G>C synonymous_variant 0.79 rifampicin
rpoC 763533 p.Thr55Ser missense_variant 0.79 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.75 rifampicin
rpoC 763550 p.Tyr61Ala missense_variant 0.75 rifampicin
rpoC 763570 c.201G>C synonymous_variant 0.79 rifampicin
rpoC 763589 p.Ile74Val missense_variant 0.75 rifampicin
rpoC 763600 c.231C>A synonymous_variant 0.71 rifampicin
rpoC 763606 c.237C>T synonymous_variant 0.67 rifampicin
rpoC 763615 c.246G>C synonymous_variant 0.52 rifampicin
rpoC 763619 p.Arg84Lys missense_variant 0.44 rifampicin
rpoC 763622 p.Ala85Ser missense_variant 0.44 rifampicin
rpoC 763625 p.Lys86Ser missense_variant 0.44 rifampicin
rpoC 763630 c.261G>C synonymous_variant 0.42 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.42 rifampicin
rpoC 763636 c.267T>C synonymous_variant 0.42 rifampicin
rpoC 763642 c.273G>C synonymous_variant 0.42 rifampicin
rpoC 763660 c.291T>C synonymous_variant 0.47 rifampicin
rpoC 763669 c.300C>G synonymous_variant 0.47 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.47 rifampicin
rpoC 763696 c.327T>C synonymous_variant 0.54 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.4 rifampicin
rpoC 764353 c.984G>C synonymous_variant 0.58 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.52 rifampicin
rpoC 764371 c.1002G>C synonymous_variant 0.57 rifampicin
rpoC 764377 c.1008C>G synonymous_variant 0.57 rifampicin
rpoC 764380 c.1011G>C synonymous_variant 0.58 rifampicin
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.62 rifampicin
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.8 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.88 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.88 rifampicin
rpoC 764432 p.Lys355Arg missense_variant 0.82 rifampicin
rpoC 764435 c.1066_1068delAGGinsCGC synonymous_variant 0.85 rifampicin
rpoC 764441 p.Ile358Leu missense_variant 0.82 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.85 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.85 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.9 rifampicin
rpoC 764461 c.1092A>G synonymous_variant 0.9 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.88 rifampicin
rpoC 764498 p.Ser377Ala missense_variant 0.8 rifampicin
rpoC 764503 c.1134G>C synonymous_variant 0.82 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.81 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 0.76 rifampicin
rpoC 764533 c.1164C>T synonymous_variant 0.43 rifampicin
rpoC 764536 c.1167G>C synonymous_variant 0.38 rifampicin
rpoC 764593 c.1224C>A synonymous_variant 0.77 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 0.77 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.77 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 0.79 rifampicin
rpoC 764632 c.1263T>C synonymous_variant 0.81 rifampicin
rpoC 764647 c.1278C>T synonymous_variant 0.79 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.82 rifampicin
rpoC 764662 c.1293G>C synonymous_variant 0.87 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 0.87 rifampicin
rpoC 764695 c.1326T>C synonymous_variant 0.82 rifampicin
rpoC 764706 p.Leu446Gln missense_variant 0.81 rifampicin
rpoC 764716 c.1347G>C synonymous_variant 0.83 rifampicin
rpoC 764737 c.1368G>C synonymous_variant 0.81 rifampicin
rpoC 764740 p.Met457Ile missense_variant 0.8 rifampicin
rpoC 764746 c.1377G>C synonymous_variant 0.7 rifampicin
rpoC 764749 c.1380G>C synonymous_variant 0.7 rifampicin
rpoC 764750 p.Val461Ile missense_variant 0.7 rifampicin
rpoC 764758 c.1389C>G synonymous_variant 0.65 rifampicin
rpoC 764760 p.Asn464Ser missense_variant 0.61 rifampicin
rpoC 764764 c.1395T>C synonymous_variant 0.68 rifampicin
rpoC 764780 p.Ser471Ala missense_variant 0.56 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.17 rifampicin
rpoC 764812 c.1443C>G synonymous_variant 0.18 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.18 rifampicin
rpoC 764824 c.1455T>C synonymous_variant 0.18 rifampicin
rpoC 764872 c.1503A>G synonymous_variant 0.42 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.55 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.43 rifampicin
rpoC 764888 c.1519_1521delTTGinsCTC synonymous_variant 0.43 rifampicin
rpoC 764893 c.1524T>C synonymous_variant 0.43 rifampicin
rpoC 764902 c.1533C>G synonymous_variant 0.36 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.45 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.45 rifampicin
rpoC 764920 c.1551G>C synonymous_variant 0.45 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.45 rifampicin
rpoC 764983 c.1614T>C synonymous_variant 0.4 rifampicin
rpoC 765119 p.Gly584Trp missense_variant 0.18 rifampicin
rpsL 781507 c.-53G>T upstream_gene_variant 0.2 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.58 streptomycin
rpsL 781685 c.126G>C synonymous_variant 0.58 streptomycin
rpsL 781706 c.147T>C synonymous_variant 0.5 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.5 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.5 streptomycin
rpsL 781721 c.162C>T synonymous_variant 0.5 streptomycin
rpsL 781724 c.165G>C synonymous_variant 0.5 streptomycin
rpsL 781728 c.169_171delTTGinsCTC synonymous_variant 0.47 streptomycin
rpsL 781731 p.Thr58Ser missense_variant 0.47 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.47 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.5 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.58 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.63 streptomycin
rpsL 781802 c.243G>C synonymous_variant 0.74 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.64 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.67 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.7 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.7 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.76 streptomycin
rpsL 781860 p.Ser101Ala missense_variant 0.76 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.76 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.76 streptomycin
rpsL 781876 p.Gly106Ala missense_variant 0.8 streptomycin
rpsL 781880 c.321C>G synonymous_variant 0.8 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.76 streptomycin
rpsL 781898 c.339A>C synonymous_variant 0.76 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.72 streptomycin
rpsL 781916 c.357T>G synonymous_variant 0.69 streptomycin
rpsL 781921 p.Lys121Met missense_variant 0.64 streptomycin
rplC 800612 c.-197A>T upstream_gene_variant 0.36 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.33 linezolid Uncertain significance
rplC 800631 c.-178_-176delTATinsGTG upstream_gene_variant 0.36 linezolid
rplC 800645 c.-164C>T upstream_gene_variant 0.33 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.33 linezolid Uncertain significance
rplC 800651 c.-158G>C upstream_gene_variant 0.31 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.29 linezolid
rplC 800667 c.-142_-140delTCGinsAGC upstream_gene_variant 0.29 linezolid
rplC 800672 c.-137G>C upstream_gene_variant 0.29 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.36 linezolid
rplC 800702 c.-107G>C upstream_gene_variant 0.36 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.38 linezolid
rplC 800715 c.-94_-92delATCinsGTG upstream_gene_variant 0.33 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.33 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.36 linezolid
rplC 800729 c.-80G>C upstream_gene_variant 0.36 linezolid
rplC 800733 c.-76A>G upstream_gene_variant 0.31 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.31 linezolid
rplC 800742 c.-67G>T upstream_gene_variant 0.31 linezolid
rplC 800753 c.-56C>T upstream_gene_variant 0.2 linezolid
rplC 800754 c.-55A>C upstream_gene_variant 0.2 linezolid
Rv1258c 1407008 c.333C>A synonymous_variant 0.18 streptomycin
pyrazinamide
isoniazid
embR 1416306 c.1041delC frameshift_variant 1.0 ethambutol Uncertain significance
rrs 1472067 n.222G>C non_coding_transcript_exon_variant 0.2 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.25 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472076 n.231G>A non_coding_transcript_exon_variant 0.25 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.37 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.82 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.83 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.83 linezolid
kanamycin Uncertain significance
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.83 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.82 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.89 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.92 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.92 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.84 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472251 n.406G>C non_coding_transcript_exon_variant 0.79 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472279 n.434T>G non_coding_transcript_exon_variant 0.61 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472284 n.439C>T non_coding_transcript_exon_variant 0.53 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.54 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.54 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.54 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.54 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472293 n.448C>A non_coding_transcript_exon_variant 0.54 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472299 n.454T>G non_coding_transcript_exon_variant 0.53 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472314 n.469A>C non_coding_transcript_exon_variant 0.51 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.57 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.57 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.59 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472333 n.488G>A non_coding_transcript_exon_variant 0.6 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.61 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.63 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.66 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.61 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.38 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.18 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.2 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.4 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.86 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.86 linezolid
kanamycin Uncertain significance
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472495 n.650C>G non_coding_transcript_exon_variant 0.86 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.87 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin Uncertain significance
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.93 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.93 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472582 n.737G>C non_coding_transcript_exon_variant 0.93 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.94 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.92 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.92 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.92 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472666 n.821G>A non_coding_transcript_exon_variant 0.93 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.93 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472674 n.829T>A non_coding_transcript_exon_variant 0.93 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.93 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.94 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.93 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.93 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472686 n.841G>T non_coding_transcript_exon_variant 0.93 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.93 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472694 n.849C>T non_coding_transcript_exon_variant 0.94 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.92 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.92 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.75 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.6 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.6 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.6 linezolid
kanamycin Uncertain significance
capreomycin
amikacin
aminoglycosides
streptomycin Uncertain significance
rrs 1472875 n.1030T>C non_coding_transcript_exon_variant 0.54 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.84 linezolid
kanamycin
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.91 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.95 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472956 n.1111T>G non_coding_transcript_exon_variant 0.96 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.96 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.94 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1472990 n.1145A>T non_coding_transcript_exon_variant 0.94 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.93 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.91 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.91 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.93 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473101 n.1256C>T non_coding_transcript_exon_variant 0.94 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.94 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.94 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473109 n.1264T>C non_coding_transcript_exon_variant 0.92 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.92 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.92 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.93 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.93 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.91 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473147 n.1302G>A non_coding_transcript_exon_variant 0.9 linezolid
kanamycin Uncertain significance
capreomycin
amikacin Uncertain significance
aminoglycosides
streptomycin Uncertain significance
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.9 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.91 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
aminoglycosides
streptomycin
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.94 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.92 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.98 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.97 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.97 linezolid
kanamycin
capreomycin
amikacin
aminoglycosides
streptomycin
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 0.97 linezolid
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin
aminoglycosides
streptomycin
rrl 1473828 n.173_174delTG non_coding_transcript_exon_variant 0.75 linezolid
rrl 1473834 n.178_179insTAG non_coding_transcript_exon_variant 0.75 linezolid
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.77 linezolid
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 0.79 linezolid
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.79 linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.79 linezolid
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 0.7 linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.95 linezolid
rrl 1474184 n.527C>A non_coding_transcript_exon_variant 0.95 linezolid
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.94 linezolid Uncertain significance
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.94 linezolid
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.91 linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.94 linezolid
rrl 1474265 n.608G>T non_coding_transcript_exon_variant 0.93 linezolid
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.92 linezolid Uncertain significance
rrl 1474275 n.618T>A non_coding_transcript_exon_variant 0.91 linezolid
rrl 1474280 n.623C>T non_coding_transcript_exon_variant 0.91 linezolid
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.91 linezolid
rrl 1474291 n.635_646delTTCCTCTCCGGA non_coding_transcript_exon_variant 0.89 linezolid
rrl 1474305 n.648G>T non_coding_transcript_exon_variant 0.89 linezolid
rrl 1474308 n.653_654delTG non_coding_transcript_exon_variant 0.89 linezolid
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.9 linezolid
rrl 1474317 n.660G>A non_coding_transcript_exon_variant 0.9 linezolid
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.9 linezolid
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.89 linezolid
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.89 linezolid
rrl 1474355 n.698A>C non_coding_transcript_exon_variant 0.89 linezolid
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.89 linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.89 linezolid
rrl 1474381 n.724T>C non_coding_transcript_exon_variant 0.84 linezolid Uncertain significance
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.76 linezolid
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 0.5 linezolid
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.5 linezolid
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.81 linezolid Uncertain significance
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.87 linezolid
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.9 linezolid
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.9 linezolid
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.9 linezolid
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.88 linezolid
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.89 linezolid
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.91 linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.92 linezolid
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.92 linezolid
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.92 linezolid
rrl 1474601 n.944C>T non_coding_transcript_exon_variant 0.93 linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.91 linezolid
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.9 linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.9 linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.92 linezolid
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.9 linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.82 linezolid
rrl 1474675 n.1018C>A non_coding_transcript_exon_variant 0.83 linezolid
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.83 linezolid
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 0.84 linezolid
rrl 1474717 n.1060_1061insGTGAG non_coding_transcript_exon_variant 0.84 linezolid
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.85 linezolid
rrl 1474723 n.1066G>A non_coding_transcript_exon_variant 0.82 linezolid
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.88 linezolid
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.86 linezolid
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.86 linezolid
rrl 1474752 n.1096delA non_coding_transcript_exon_variant 0.87 linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.9 linezolid
rrl 1474770 n.1113G>A non_coding_transcript_exon_variant 0.89 linezolid
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.9 linezolid
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.89 linezolid
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.89 linezolid
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.89 linezolid
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 0.91 linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.92 linezolid
rrl 1474800 n.1143T>C non_coding_transcript_exon_variant 0.92 linezolid
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.9 linezolid
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.89 linezolid
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.89 linezolid
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.87 linezolid
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.86 linezolid
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.94 linezolid
rrl 1474920 n.1263G>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474935 n.1278A>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1474938 n.1281G>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475060 n.1404delC non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475065 n.1408G>A non_coding_transcript_exon_variant 1.0 linezolid Uncertain significance
rrl 1475067 n.1410A>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475068 n.1411A>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475078 n.1421T>C non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475084 n.1427G>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475108 n.1451C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475111 n.1454G>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 1.0 linezolid Uncertain significance
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475119 n.1462C>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 1.0 linezolid
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.3 linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.57 linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.62 linezolid
rrl 1475692 n.2035G>C non_coding_transcript_exon_variant 0.85 linezolid
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.91 linezolid
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 0.91 linezolid
rrl 1475760 n.2103C>T non_coding_transcript_exon_variant 0.91 linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.91 linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.91 linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.91 linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.91 linezolid
rrl 1475767 n.2110G>A non_coding_transcript_exon_variant 0.9 linezolid
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.9 linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.91 linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.97 linezolid
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.97 linezolid
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.98 linezolid
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.98 linezolid
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.97 linezolid
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.98 linezolid
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.99 linezolid
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.98 linezolid
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.98 linezolid
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.98 linezolid
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.97 linezolid
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.96 linezolid
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.95 linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.94 linezolid Uncertain significance
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.87 linezolid
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.87 linezolid Uncertain significance
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.88 linezolid
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.6 linezolid
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.62 linezolid
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.62 linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.73 linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.83 linezolid
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.86 linezolid
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.9 linezolid
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.9 linezolid
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.9 linezolid
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.92 linezolid
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.91 linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.95 linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.94 linezolid
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.94 linezolid
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.94 linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.94 linezolid
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.92 linezolid
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.92 linezolid
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.92 linezolid
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.91 linezolid
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.91 linezolid
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.92 linezolid
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.91 linezolid
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.93 linezolid
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.92 linezolid
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.94 linezolid
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.92 linezolid
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.9 linezolid
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.92 linezolid Uncertain significance
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.92 linezolid
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.93 linezolid
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.93 linezolid
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.94 linezolid
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.94 linezolid
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.94 linezolid
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.94 linezolid
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.94 linezolid
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.94 linezolid
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.94 linezolid
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.94 linezolid
rrl 1476544 n.2887T>A non_coding_transcript_exon_variant 0.94 linezolid
rrl 1476566 n.2909A>T non_coding_transcript_exon_variant 0.91 linezolid
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.91 linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.93 linezolid
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.93 linezolid
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.94 linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.93 linezolid
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.88 linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.85 linezolid
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.67 linezolid
rpsA 1833921 p.Lys127Thr missense_variant 0.36 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.47 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.7 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 0.68 pyrazinamide
rpsA 1833959 p.Leu140Val missense_variant 0.72 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.68 pyrazinamide
rpsA 1833973 c.432G>C synonymous_variant 0.7 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.7 pyrazinamide
rpsA 1833985 c.444G>C synonymous_variant 0.7 pyrazinamide
rpsA 1833988 c.447C>G synonymous_variant 0.7 pyrazinamide
rpsA 1833997 c.456G>C synonymous_variant 0.66 pyrazinamide
rpsA 1833998 p.Val153Ile missense_variant 0.67 pyrazinamide
rpsA 1834004 p.Met155Leu missense_variant 0.67 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.67 pyrazinamide
rpsA 1834024 c.483G>C synonymous_variant 0.73 pyrazinamide
rpsA 1834025 p.Gln162Thr missense_variant 0.73 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.73 pyrazinamide
rpsA 1834034 p.Ile165Leu missense_variant 0.71 pyrazinamide
rpsA 1834040 p.Lys167Gln missense_variant 0.73 pyrazinamide
rpsA 1834054 c.513C>G synonymous_variant 0.71 pyrazinamide
rpsA 1834061 p.Ile174Leu missense_variant 0.66 pyrazinamide
rpsA 1834066 c.525G>A synonymous_variant 0.67 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.65 pyrazinamide
rpsA 1834093 c.552G>C synonymous_variant 0.17 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide
rpsA 1834378 c.837T>G synonymous_variant 0.71 pyrazinamide
rpsA 1834384 c.843A>G synonymous_variant 0.71 pyrazinamide
rpsA 1834395 p.Arg285Gln missense_variant 0.86 pyrazinamide
rpsA 1834397 p.His286Val missense_variant 0.86 pyrazinamide
rpsA 1834408 c.867C>T synonymous_variant 0.86 pyrazinamide
rpsA 1834411 c.870T>G synonymous_variant 0.86 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.86 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.86 pyrazinamide
rpsA 1834427 p.Ile296Val missense_variant 0.86 pyrazinamide
rpsA 1834430 p.Val297Thr missense_variant 0.86 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.86 pyrazinamide
rpsA 1834438 c.897C>A synonymous_variant 0.86 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.86 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.86 pyrazinamide
rpsA 1834482 p.Glu314Ala missense_variant 0.86 pyrazinamide
rpsA 1834486 p.Glu315Asp missense_variant 0.86 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834501 c.960G>C synonymous_variant 0.86 pyrazinamide
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Uncertain significance
fbiB 3640881 c.-654G>T upstream_gene_variant 0.2 delamanid
ddn 3986954 c.111G>T synonymous_variant 0.17 delamanid
ddn 3987179 c.336G>T synonymous_variant 0.14 delamanid
clpC1 4039508 c.1197G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039533 p.Asn391Ser missense_variant 0.69 pyrazinamide
clpC1 4039550 c.1155G>C synonymous_variant 0.71 pyrazinamide
clpC1 4039554 p.Thr384Asn missense_variant 0.71 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.71 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.71 pyrazinamide
clpC1 4039568 p.Met379Ile missense_variant 0.71 pyrazinamide
clpC1 4039574 p.Ala377Gly missense_variant 0.71 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.71 pyrazinamide
clpC1 4039593 p.Arg371Lys missense_variant 0.8 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.75 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039622 c.1083C>G synonymous_variant 0.73 pyrazinamide
clpC1 4039628 c.1077C>G synonymous_variant 0.79 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.9 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039747 p.Ile320Val missense_variant 0.92 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039773 p.Lys311Leu missense_variant 0.86 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.89 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.91 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.79 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 0.78 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 0.74 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.74 pyrazinamide
clpC1 4039838 p.Leu289Ile missense_variant 0.64 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.6 pyrazinamide
clpC1 4039853 p.Leu284Val missense_variant 0.6 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.58 pyrazinamide
clpC1 4039871 c.834C>G synonymous_variant 0.5 pyrazinamide
clpC1 4039875 p.Asn277Arg missense_variant 0.5 pyrazinamide
clpC1 4039887 p.Leu273Thr missense_variant 0.47 pyrazinamide
clpC1 4039889 c.816G>C synonymous_variant 0.42 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.47 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.47 pyrazinamide
clpC1 4039916 c.789T>C synonymous_variant 0.44 pyrazinamide
clpC1 4039929 p.Ser259Thr missense_variant 0.18 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.33 pyrazinamide
clpC1 4039960 p.Thr249Ser missense_variant 0.59 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.77 pyrazinamide
clpC1 4040000 p.His235Lys missense_variant 0.89 pyrazinamide
clpC1 4040003 c.702G>C synonymous_variant 0.89 pyrazinamide
clpC1 4040009 c.696C>G synonymous_variant 0.89 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 0.87 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.87 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 0.87 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040063 c.642G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040066 c.639G>C synonymous_variant 0.86 pyrazinamide
clpC1 4040069 c.636G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040083 p.Thr208Ser missense_variant 0.97 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040090 c.615T>G synonymous_variant 0.94 pyrazinamide
clpC1 4040096 p.Val203Ile missense_variant 0.94 pyrazinamide
clpC1 4040117 c.588A>G synonymous_variant 0.93 pyrazinamide
embC 4240289 p.Pro143Thr missense_variant 0.13 ethambutol
embA 4246417 p.Arg1062Leu missense_variant 0.17 ethambutol Uncertain significance
ethA 4327863 c.-390G>T upstream_gene_variant 0.15 ethionamide
ethA 4327926 c.-453G>T upstream_gene_variant 0.18 ethionamide
ethA 4328470 c.-997G>T upstream_gene_variant 0.18 ethionamide
gid 4407927 p.Glu92Asp missense_variant 1.0 streptomycin Uncertain significance