TB-Profiler result

Run: ERR4816762
Summary

Run ID: ERR4816762

Sample name:

Date: 2024-10-03T20:05:53.783463

Number of reads: 144581

Percentage reads mapped: 7.75

Median coverage: 2.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.95
lineage4.9 Euro-American (H37Rv-like) None 0.88
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 6115 c.876A>G synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrB 6122 p.Ala295Ser missense_variant 0.72 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrB 6139 c.900G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrB 6169 c.930C>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8294 c.993T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8305 p.Thr335Ser missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8309 c.1008G>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8366 c.1065G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8849 c.1548C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8864 c.1563C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8934 p.Gln545Lys missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8944 p.Gly548Asp missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8966 c.1665C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8996 c.1695T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.88 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
hadA 731774 c.-156T>C upstream_gene_variant 0.73 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.75 isoniazid
hadA 731798 c.-132C>T upstream_gene_variant 0.86 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 0.86 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 0.86 isoniazid
hadA 731813 c.-117C>T upstream_gene_variant 0.86 isoniazid
hadA 731816 c.-114G>C upstream_gene_variant 0.92 isoniazid
hadA 731819 c.-111G>C upstream_gene_variant 0.92 isoniazid
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734454 c.201A>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734463 c.210G>C synonymous_variant 1.0 rifampicin
nusG 734472 c.219T>C synonymous_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734505 c.252G>C synonymous_variant 0.95 rifampicin
nusG 734514 c.261A>G synonymous_variant 0.94 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
nusG 734543 p.Arg97Gln missense_variant 0.91 rifampicin
nusG 734549 p.Gln99Arg missense_variant 0.91 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.77 rifampicin
rpoB 760223 c.417T>C synonymous_variant 0.88 rifampicin
rpoB 760233 c.427_429delAGTinsTCG synonymous_variant 0.88 rifampicin
rpoB 760241 c.435G>C synonymous_variant 0.88 rifampicin
rpoB 760244 c.438G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760262 c.456G>C synonymous_variant 0.93 rifampicin
rpoB 760271 c.465C>G synonymous_variant 0.93 rifampicin
rpoB 760274 p.Glu156Asp missense_variant 0.93 rifampicin Uncertain significance
rpoB 760380 p.Thr192Pro missense_variant 1.0 rifampicin
rpoB 760394 c.588C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760400 c.594G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760407 p.Ser201Ala missense_variant 0.93 rifampicin
rpoB 760430 c.624T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760436 c.630C>G synonymous_variant 0.95 rifampicin
rpoB 760460 c.654G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760487 c.681G>C synonymous_variant 0.94 rifampicin
rpoB 760508 c.702G>C synonymous_variant 1.0 rifampicin
rpoB 760511 c.705G>C synonymous_variant 1.0 rifampicin
rpoB 760514 c.708C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Leu missense_variant 1.0 rifampicin
rpoB 760541 c.735G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760553 c.747C>G synonymous_variant 0.88 rifampicin
rpoB 760565 c.759A>G synonymous_variant 0.86 rifampicin
rpoB 760568 c.762G>C synonymous_variant 0.86 rifampicin
rpoB 760571 c.765G>C synonymous_variant 0.86 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.88 rifampicin
rpoB 760611 c.805_807delTTGinsCTC synonymous_variant 0.82 rifampicin
rpoB 760634 c.828T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.85 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760925 c.1119T>C synonymous_variant 0.92 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760953 p.Ile383Leu missense_variant 0.93 rifampicin
rpoB 760958 c.1152G>C synonymous_variant 0.93 rifampicin
rpoB 760961 c.1155C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.93 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.93 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.92 rifampicin
rpoB 761063 c.1257C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761088 c.1282_1284delAGCinsTCG synonymous_variant 0.91 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.91 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.92 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761138 c.1332C>G synonymous_variant 1.0 rifampicin
rpoB 761147 c.1341C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 1.0 rifampicin
rpoB 761162 c.1356G>C synonymous_variant 1.0 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761174 c.1368T>C synonymous_variant 1.0 rifampicin
rpoB 761180 c.1374A>G synonymous_variant 1.0 rifampicin
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761213 c.1407G>C synonymous_variant 1.0 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 0.95 rifampicin
rpoB 761318 c.1512G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761549 c.1743G>C synonymous_variant 1.0 rifampicin
rpoB 761555 c.1749G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761612 c.1806G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761633 c.1827G>C synonymous_variant 1.0 rifampicin
rpoB 761999 c.2193G>C synonymous_variant 0.94 rifampicin
rpoB 762002 c.2196C>G synonymous_variant 0.94 rifampicin
rpoB 762003 p.Asn733Gln missense_variant 0.94 rifampicin
rpoB 762014 c.2208C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762032 c.2226C>G synonymous_variant 1.0 rifampicin
rpoB 762035 c.2229G>C synonymous_variant 1.0 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762074 c.2268C>G synonymous_variant 0.83 rifampicin
rpoB 762114 p.Ile770Val missense_variant 0.71 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.75 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.69 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.69 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 762156 p.Val784Ile missense_variant 0.76 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 0.85 rifampicin
rpoB 762905 p.Asp1033Glu missense_variant 0.87 rifampicin
rpoB 762920 c.3114C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 762947 c.-423C>G upstream_gene_variant 0.91 rifampicin
rpoB 762962 c.3156C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.95 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 0.95 rifampicin
rpoB 762995 c.3189G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 763053 c.-317_-315delTTGinsCTC upstream_gene_variant 0.94 rifampicin
rpoC 763067 c.-303C>G upstream_gene_variant 0.92 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 763074 p.Thr1090Val missense_variant 0.95 rifampicin
rpoB 763088 c.3282C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 1.0 rifampicin
rpoC 763139 c.-231C>T upstream_gene_variant 1.0 rifampicin
rpoC 763468 c.99G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763507 c.138G>C synonymous_variant 0.86 rifampicin
rpoC 763528 c.159G>C synonymous_variant 0.88 rifampicin
rpoC 763534 c.165T>C synonymous_variant 0.9 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763558 c.189C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 0.9 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>C synonymous_variant 0.94 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.91 rifampicin
rpoC 763711 c.342G>C synonymous_variant 0.9 rifampicin
rpoC 763717 c.348T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 0.93 rifampicin
rpoC 763735 c.366G>C synonymous_variant 0.93 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.9 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.88 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.88 rifampicin
rpoC 763780 c.411C>G synonymous_variant 0.89 rifampicin
rpoC 763781 p.Ser138Glu missense_variant 0.89 rifampicin
rpoC 763796 p.Met143Gln missense_variant 0.83 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763812 p.Leu148Gln missense_variant 0.83 rifampicin
rpoC 763917 p.Glu183Val missense_variant 0.7 rifampicin
rpoC 763921 c.552G>C synonymous_variant 0.7 rifampicin
rpoC 763945 c.576T>C synonymous_variant 0.7 rifampicin
rpoC 763946 p.Ala193Gln missense_variant 0.7 rifampicin
rpoC 763951 c.582G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764278 c.909A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 764297 p.Met310Leu missense_variant 0.9 rifampicin
rpoC 764308 c.939G>C synonymous_variant 0.92 rifampicin
rpoC 764317 c.948C>G synonymous_variant 0.89 rifampicin
rpoC 764320 c.951C>G synonymous_variant 0.91 rifampicin
rpoC 764353 c.984G>C synonymous_variant 0.96 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764398 c.1029G>C synonymous_variant 0.95 rifampicin
rpoC 764404 c.1035C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764428 c.1059G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.92 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.93 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.93 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.88 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 0.79 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.88 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.92 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 1.0 rifampicin
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764635 c.1266C>G synonymous_variant 1.0 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764662 c.1293G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764665 c.1296C>G synonymous_variant 0.94 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764695 c.1326T>C synonymous_variant 0.91 rifampicin
rpoC 764701 c.1332C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>C synonymous_variant 0.92 rifampicin
rpoC 764755 c.1386C>T synonymous_variant 0.96 rifampicin
rpoC 764764 c.1395T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764780 c.1411_1413delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoC 764797 c.1428G>C synonymous_variant 0.96 rifampicin
rpoC 764803 c.1434C>G synonymous_variant 0.96 rifampicin
rpoC 764812 c.1443C>G synonymous_variant 0.92 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764854 c.1485G>C synonymous_variant 0.87 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764863 c.1494G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>G synonymous_variant 0.6 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1643delAGinsTC synonymous_variant 0.69 rifampicin
rpoC 765016 c.1647C>G synonymous_variant 0.64 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.79 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.78 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720_1722delTTGinsCTC synonymous_variant 0.8 rifampicin
rpoC 765100 c.1731G>C synonymous_variant 0.76 rifampicin
rpoC 765103 c.1734G>T synonymous_variant 0.8 rifampicin
rpoC 765121 c.1752G>C synonymous_variant 0.67 rifampicin
rpoC 765844 c.2475C>G synonymous_variant 0.89 rifampicin
rpoC 765875 p.Val836Ile missense_variant 0.86 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.91 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765904 c.2535C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>G synonymous_variant 0.88 rifampicin
rpoC 765940 c.2571A>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.86 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.86 rifampicin
rpoC 765955 c.2586C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765961 c.2592G>T synonymous_variant 0.86 rifampicin
rpoC 765962 c.2593T>C synonymous_variant 0.86 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 1.0 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 1.0 rifampicin
rpoC 766375 c.3006C>G synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 1.0 rifampicin
rpoC 766402 c.3033C>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766435 p.Glu1022Asp missense_variant 1.0 rifampicin Uncertain significance
rpoC 766835 p.Val1156Thr missense_variant 0.77 rifampicin
rpoC 766843 c.3474T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 766933 c.3564A>G synonymous_variant 1.0 rifampicin
rpoC 766948 c.3579G>C synonymous_variant 0.9 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766990 c.3621G>C synonymous_variant 0.92 rifampicin
rpoC 767002 c.3633G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>C synonymous_variant 0.92 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 0.91 rifampicin
rpoC 767017 c.3648C>G synonymous_variant 0.9 rifampicin
rpsL 781751 c.192G>C synonymous_variant 0.67 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.8 streptomycin
rpsL 781769 c.210G>A synonymous_variant 0.71 streptomycin
rpsL 781781 c.222G>T synonymous_variant 0.78 streptomycin
rpsL 781802 c.243G>C synonymous_variant 0.86 streptomycin
rpsL 781805 c.246G>C synonymous_variant 0.89 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.92 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.92 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.93 streptomycin
rpsL 781832 c.273T>G synonymous_variant 0.93 streptomycin
rpsL 781838 c.279G>T synonymous_variant 0.91 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.9 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.9 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.9 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.91 streptomycin
rpsL 781898 c.339A>G synonymous_variant 0.91 streptomycin
rpsL 781901 c.342C>G synonymous_variant 0.91 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.91 streptomycin
rpsL 781916 c.357T>G synonymous_variant 0.88 streptomycin
rrs 1471918 n.73A>T non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471926 n.81C>T non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.9 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.9 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471938 n.93T>A non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471972 n.127T>C non_coding_transcript_exon_variant 0.87 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471981 n.136C>T non_coding_transcript_exon_variant 0.85 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472396 n.551A>T non_coding_transcript_exon_variant 0.86 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.89 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.9 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473081 n.1236C>G non_coding_transcript_exon_variant 0.96 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473082 n.1237G>C non_coding_transcript_exon_variant 0.96 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473129 n.1284C>G non_coding_transcript_exon_variant 0.93 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473130 n.1285G>C non_coding_transcript_exon_variant 0.95 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473679 n.22T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473695 n.38A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473698 n.41G>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473757 n.100T>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473793 n.136G>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473797 n.140G>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473802 n.145C>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1473816 n.159C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1473828 n.171_176delGGTGCGinsACGGTGT non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1473844 n.187C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473870 n.213G>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473922 n.265A>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473933 n.276_277insAT non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1473936 n.281_282delGC non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1473968 n.311C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473971 n.314G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474127 n.470G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474139 n.482C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524_530delCCTCGATinsACCTTGC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474353 n.696A>C non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1474355 n.698A>C non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474356 n.699T>G non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474375 n.718G>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474376 n.719T>G non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474498 n.841G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474505 n.848C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474674 n.1017A>C non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474675 n.1018C>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060_1061insGTGAG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474822 n.1165G>C non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474896 n.1239A>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474902 n.1245T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474905 n.1248T>G non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475060 n.1404delC non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475063 n.1406A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475065 n.1408G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475084 n.1427G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475109 n.1452C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475113 n.1456C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475536 n.1879C>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475655 n.1998T>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475688 n.2031G>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475713 n.2056C>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475758 n.2101_2102delACinsG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475768 n.2111_2112delGTinsC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476047 n.2390G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476087 n.2430C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476091 n.2434_2435insC non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.95 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.93 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833661 c.120A>G synonymous_variant 0.83 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.88 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 0.89 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.91 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 0.94 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.91 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.94 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.94 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.9 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.94 pyrazinamide
rpsA 1833746 c.205_206delTCinsAG synonymous_variant 0.89 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.82 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.82 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 0.85 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.85 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.91 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.96 pyrazinamide
rpsA 1833859 c.318C>T synonymous_variant 0.97 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.97 pyrazinamide
rpsA 1833886 c.345C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.98 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833952 c.411C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833961 c.420C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833973 c.432G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833985 c.444G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833988 c.447C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834024 c.483G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834054 c.513C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834093 c.552G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.96 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 0.91 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834298 p.Gln253Thr missense_variant 0.97 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.97 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834340 p.Met267Leu missense_variant 0.94 pyrazinamide Uncertain significance
rpsA 1834348 c.807T>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
rpsA 1834354 c.813G>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
rpsA 1834378 c.837T>C synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
rpsA 1834384 c.843A>G synonymous_variant 0.88 pyrazinamide
rpsA 1834387 c.846C>T synonymous_variant 0.83 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.85 pyrazinamide
rpsA 1834399 p.His286Gln missense_variant 0.86 pyrazinamide
rpsA 1834408 c.867C>G synonymous_variant 0.82 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.78 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.87 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.82 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.84 pyrazinamide
rpsA 1834451 c.910_912delTTGinsCTC synonymous_variant 0.85 pyrazinamide
rpsA 1834456 c.915T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.85 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834501 c.960G>C synonymous_variant 0.85 pyrazinamide
rpsA 1834504 c.963G>C synonymous_variant 0.83 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.79 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.84 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.87 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834700 p.Gln387Asn missense_variant 0.88 pyrazinamide
rpsA 1834706 p.Asn389Glu missense_variant 0.88 pyrazinamide
rpsA 1834733 p.Ala398Pro missense_variant 0.96 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.92 pyrazinamide
rpsA 1834747 c.1206A>G synonymous_variant 0.95 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.88 pyrazinamide
rpsA 1834765 c.1224A>G synonymous_variant 0.88 pyrazinamide
kasA 2517921 c.-194_-193delACinsCT upstream_gene_variant 1.0 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
ahpC 2726636 c.444G>C synonymous_variant 0.88 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 0.88 isoniazid
ahpC 2726642 c.450C>G synonymous_variant 0.88 isoniazid
ahpC 2726651 c.459G>C synonymous_variant 0.88 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 0.88 isoniazid Not assoc w R - Interim
ahpC 2726669 c.477T>C synonymous_variant 0.87 isoniazid
ahpC 2726675 c.483A>G synonymous_variant 0.86 isoniazid
ahpC 2726678 c.486G>C synonymous_variant 0.8 isoniazid
ahpC 2726681 c.489A>C synonymous_variant 0.8 isoniazid Not assoc w R - Interim
ahpC 2726696 c.504C>G synonymous_variant 0.73 isoniazid
thyA 3073953 c.519T>C synonymous_variant 0.91 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.91 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.91 para-aminosalicylic_acid
thyA 3073962 c.510G>C synonymous_variant 0.91 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3073999 p.Arg158Lys missense_variant 0.92 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074010 p.Val154Ala missense_variant 0.92 para-aminosalicylic_acid
mtrB 3627071 c.-458G>C upstream_gene_variant 0.79 rifampicin
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627083 c.-470G>C upstream_gene_variant 0.86 rifampicin
bedaquiline
rpoA 3877587 p.Ser307Ala missense_variant 0.71 rifampicin
rpoA 3877593 c.915C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3877600 p.Gln303Ala missense_variant 0.71 rifampicin
rpoA 3877613 p.Ile299Val missense_variant 0.8 rifampicin
rpoA 3877617 c.891G>C synonymous_variant 0.81 rifampicin
rpoA 3877629 c.879C>G synonymous_variant 0.85 rifampicin
rpoA 3877656 c.852T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3877659 c.849G>T synonymous_variant 0.84 rifampicin
rpoA 3877668 c.840A>G synonymous_variant 0.9 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3877683 c.825G>C synonymous_variant 0.91 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.95 rifampicin
rpoA 3877731 c.777G>C synonymous_variant 0.89 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877746 c.762G>C synonymous_variant 0.95 rifampicin
rpoA 3877752 p.Asp252Glu missense_variant 0.95 rifampicin
rpoA 3877764 p.Ala248Ser missense_variant 0.89 rifampicin
rpoA 3877770 p.Ser246Ala missense_variant 0.82 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877803 c.705G>C synonymous_variant 0.88 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877935 p.Lys191Arg missense_variant 0.82 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3878082 c.426T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3878102 p.Val136Ile missense_variant 0.9 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.9 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.9 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.82 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 0.83 rifampicin
rpoA 3878141 p.Met123Leu missense_variant 0.81 rifampicin Uncertain significance
rpoA 3878143 p.Gly122Asp missense_variant 0.82 rifampicin Uncertain significance
rpoA 3878154 c.354G>C synonymous_variant 0.8 rifampicin
rpoA 3878161 c.345_346delCG frameshift_variant 0.7 rifampicin
rpoA 3878166 c.341_342insGT frameshift_variant 0.7 rifampicin
rpoA 3878175 c.333G>C synonymous_variant 0.77 rifampicin
rpoA 3878187 c.321C>G synonymous_variant 0.67 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoA 3878196 p.Glu104Ala missense_variant 0.67 rifampicin Uncertain significance
rpoA 3878199 c.309T>C synonymous_variant 0.71 rifampicin
rpoA 3878217 p.Leu97Val missense_variant 0.81 rifampicin
rpoA 3878241 p.Glu89Asp missense_variant 0.91 rifampicin
rpoA 3878250 c.258C>G synonymous_variant 0.9 rifampicin
rpoA 3878253 c.255G>C synonymous_variant 0.9 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.86 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.86 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.8 rifampicin Uncertain significance
rpoA 3878295 c.213A>G synonymous_variant 0.92 rifampicin
rpoA 3878298 c.210A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.8 rifampicin
rpoA 3878310 c.198G>C synonymous_variant 0.8 rifampicin
clpC1 4038755 c.1950G>C synonymous_variant 0.77 pyrazinamide
clpC1 4038764 c.1941C>G synonymous_variant 0.64 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 0.64 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.64 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.69 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.75 pyrazinamide
clpC1 4038794 p.Ser637Thr missense_variant 0.71 pyrazinamide
clpC1 4038808 c.1896_1897insC frameshift_variant 0.78 pyrazinamide
clpC1 4038811 c.1893delT frameshift_variant 0.78 pyrazinamide
clpC1 4038836 c.1869G>C synonymous_variant 0.86 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.77 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4038899 c.1806C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038905 c.1800A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.94 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038926 c.1779G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038932 c.1773G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038986 p.Asp573Glu missense_variant 1.0 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039007 c.1698G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039016 c.1689C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039034 c.1671C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039130 c.1575C>G synonymous_variant 0.9 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.94 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039181 c.1522_1524delTTGinsCTC synonymous_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 1.0 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039238 c.1467C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039244 c.1461G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039642 p.Thr355Ala missense_variant 0.74 pyrazinamide
clpC1 4039645 p.His354Asp missense_variant 0.23 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039652 p.Thr351Ser missense_variant 0.92 pyrazinamide
clpC1 4039661 p.Gly348Arg missense_variant 0.65 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.66 pyrazinamide
clpC1 4039668 p.Gln346Met missense_variant 0.31 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 0.65 pyrazinamide
clpC1 4039673 c.1032G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.26 pyrazinamide
clpC1 4039688 c.1017G>A synonymous_variant 0.25 pyrazinamide Not assoc w R - Interim
clpC1 4039691 c.1014G>C synonymous_variant 0.27 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.26 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.72 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.87 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.87 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.88 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.9 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.9 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.89 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039811 c.894C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039814 c.891C>T synonymous_variant 0.95 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.89 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 0.89 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.89 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039943 c.762G>C synonymous_variant 0.58 pyrazinamide
clpC1 4039946 c.759A>G synonymous_variant 0.64 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.64 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.69 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.69 pyrazinamide
clpC1 4039994 p.Glu237Asn missense_variant 0.93 pyrazinamide
clpC1 4040002 p.His235Asn missense_variant 0.9 pyrazinamide
clpC1 4040003 c.702G>C synonymous_variant 0.9 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.9 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.9 pyrazinamide
clpC1 4040057 c.648C>T synonymous_variant 0.89 pyrazinamide
clpC1 4040063 c.642G>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4040090 c.615T>G synonymous_variant 0.88 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>T synonymous_variant 0.82 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.82 pyrazinamide
clpC1 4040486 c.219G>C synonymous_variant 0.82 pyrazinamide
clpC1 4040501 c.204C>G synonymous_variant 0.82 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 0.75 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim