TB-Profiler result

Run: ERR4815310
Summary

Run ID: ERR4815310

Sample name:

Date: 2024-03-26T13:50:13.980204

Number of reads: 295860

Percentage reads mapped: 20.2

Median coverage: 5.0

Strain: lineage2.2.1;lineage4.9

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage2 East-Asian RD105 0.49
lineage2.2.1 East-Asian (Beijing) RD105;RD207;RD181 0.26
lineage2.2 East-Asian (Beijing) RD105;RD207 0.28
lineage4.9 Euro-American (H37Rv-like) None 0.68
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin rrs n.799C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
rpoB 760271 c.465C>G synonymous_variant 0.38 rifampicin
rpoB 760274 p.Glu156Asp missense_variant 0.38 rifampicin Uncertain significance
rpoB 761174 c.1368T>C synonymous_variant 0.64 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.86 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761252 c.1446C>G synonymous_variant 0.75 rifampicin
rpoB 761261 c.1455G>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761276 c.1470G>C synonymous_variant 0.74 rifampicin
rpoB 761292 p.Val496Ser missense_variant 0.72 rifampicin
rpoB 761312 c.1506G>C synonymous_variant 0.68 rifampicin
rpoB 761318 c.1512G>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761534 c.1728G>C synonymous_variant 0.68 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 761540 c.1734C>G synonymous_variant 0.68 rifampicin
rpoB 761549 c.1743G>C synonymous_variant 0.76 rifampicin
rpoB 761552 c.1746G>C synonymous_variant 0.77 rifampicin
rpoB 761558 c.1752C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.8 rifampicin
rpoB 761570 c.1764T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761612 c.1806G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761633 c.1827G>C synonymous_variant 0.72 rifampicin
rpoB 761643 p.Val613Leu missense_variant 0.76 rifampicin
rpoB 761648 c.1842T>C synonymous_variant 0.74 rifampicin
rpoB 761649 c.1843_1844delAGinsTC synonymous_variant 0.74 rifampicin
rpoB 761661 c.1855_1857delCTGinsTC frameshift_variant&missense_variant 0.73 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 0.67 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.6 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.6 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.6 rifampicin
rpoB 761890 p.Val695Ala missense_variant 0.6 rifampicin
rpoB 761903 c.2097T>C synonymous_variant 0.71 rifampicin
rpoB 761907 c.2101_2103delTGTinsGC frameshift_variant&missense_variant 0.71 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.72 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.76 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.81 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761951 c.2145G>C synonymous_variant 0.94 rifampicin
rpoB 761955 p.Ile717Phe missense_variant 0.95 rifampicin
rpoB 761998 c.2193_2195delGTC disruptive_inframe_deletion 0.94 rifampicin
rpoB 762005 c.2200_2201insAGC disruptive_inframe_insertion 0.93 rifampicin
rpoB 762009 p.Leu735Met missense_variant 0.93 rifampicin
rpoB 762014 c.2208C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762074 c.2268C>G synonymous_variant 0.94 rifampicin
rpoB 762080 c.2274G>C synonymous_variant 0.95 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762084 p.Ala760Pro missense_variant 0.95 rifampicin
rpoB 762101 c.2295C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.81 rifampicin Uncertain significance
rpoB 762117 p.Ser771Gly missense_variant 0.76 rifampicin
rpoB 762122 p.Asp772Glu missense_variant 0.76 rifampicin
rpoB 762125 p.Glu773Asp missense_variant 0.76 rifampicin
rpoB 762128 c.2322G>C synonymous_variant 0.76 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.81 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.81 rifampicin
rpoB 762146 p.Glu780Asp missense_variant 0.81 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762173 p.Glu789Asp missense_variant 0.87 rifampicin
rpoB 762176 c.2370T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 762842 c.-528G>C upstream_gene_variant 0.8 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762858 c.3052_3054delACGinsTC frameshift_variant&missense_variant 0.83 rifampicin
rpoC 762863 c.-507T>G upstream_gene_variant 0.83 rifampicin
rpoB 762878 p.Ile1024Met missense_variant 0.9 rifampicin
rpoB 762879 c.3073_3075delATGinsCC frameshift_variant&missense_variant 0.9 rifampicin
rpoC 762896 c.-474G>C upstream_gene_variant 0.92 rifampicin
rpoB 762905 p.Asp1033Glu missense_variant 0.95 rifampicin
rpoC 762926 c.-444C>G upstream_gene_variant 0.96 rifampicin
rpoB 762929 c.3123G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 762938 c.-432G>C upstream_gene_variant 0.96 rifampicin
rpoB 762959 c.3153G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 762971 c.-399G>C upstream_gene_variant 0.97 rifampicin
rpoC 762983 c.-387C>A upstream_gene_variant 0.96 rifampicin
rpoB 762989 c.3183G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763005 p.Cys1067Val missense_variant 0.98 rifampicin
rpoC 763022 c.-348C>G upstream_gene_variant 0.95 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763043 c.-327G>C upstream_gene_variant 0.88 rifampicin
rpoC 763049 c.-321G>A upstream_gene_variant 0.89 rifampicin
rpoC 763052 c.-318G>C upstream_gene_variant 0.86 rifampicin
rpoB 763053 c.3247_3249delTTGinsCC frameshift_variant&missense_variant 0.86 rifampicin
rpoC 763058 c.-312C>G upstream_gene_variant 0.8 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 763074 p.Thr1090Val missense_variant 0.77 rifampicin
rpoB 763085 c.3279C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 763088 c.3282C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>C upstream_gene_variant 0.72 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 763130 p.Glu1108Asp missense_variant 0.42 rifampicin
rpoC 763148 c.-222G>C upstream_gene_variant 0.44 rifampicin
rpoC 763442 c.73_75delTATinsAG frameshift_variant&missense_variant 0.9 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763462 c.93G>C synonymous_variant 0.95 rifampicin
rpoC 763468 c.99G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763483 c.114G>C synonymous_variant 0.93 rifampicin
rpoC 763486 c.117T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763517 p.Lys50Arg missense_variant 0.91 rifampicin
rpoC 763528 c.159G>C synonymous_variant 0.91 rifampicin
rpoC 763534 c.165T>C synonymous_variant 0.91 rifampicin
rpoC 763537 c.168C>G synonymous_variant 0.91 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763550 p.Tyr61Ala missense_variant 0.91 rifampicin
rpoC 763570 c.201G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763578 p.Phe70Tyr missense_variant 0.94 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763630 c.261G>C synonymous_variant 0.94 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.94 rifampicin
rpoC 763660 c.291T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763672 c.303C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763711 c.342G>C synonymous_variant 0.87 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.83 rifampicin
rpoC 763729 c.360G>C synonymous_variant 0.81 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.64 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.64 rifampicin
rpoC 764353 c.984G>C synonymous_variant 0.65 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.88 rifampicin
rpoC 764491 c.1122G>C synonymous_variant 0.91 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 0.9 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>G synonymous_variant 0.88 rifampicin
rpoC 764530 c.1161C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.94 rifampicin
rpoC 764545 c.1176C>G synonymous_variant 0.96 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764572 c.1203G>C synonymous_variant 0.94 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764581 c.1212T>C synonymous_variant 0.97 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764635 c.1266C>G synonymous_variant 0.97 rifampicin
rpoC 764644 c.1275G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764647 c.1278C>G synonymous_variant 0.97 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764653 c.1284G>C synonymous_variant 0.98 rifampicin
rpoC 764660 c.1291_1293delGTGinsAC frameshift_variant&missense_variant 0.97 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764707 c.1338G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764857 c.1488G>C synonymous_variant 0.5 rifampicin
rpoC 764858 p.Leu497Met missense_variant 0.53 rifampicin
rpoC 764863 c.1494G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.65 rifampicin
rpoC 764902 c.1533C>G synonymous_variant 0.68 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.67 rifampicin
rpoC 764914 p.Met515Ile missense_variant 0.67 rifampicin Uncertain significance
rpoC 764917 c.1548G>C synonymous_variant 0.67 rifampicin
rpoC 764920 c.1551G>C synonymous_variant 0.67 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.69 rifampicin
rpoC 764941 c.1572G>C synonymous_variant 0.69 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764952 p.Val528Ala missense_variant 0.75 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766800 p.Ala1144Asp missense_variant 0.62 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 766811 c.3442_3444delTCGinsGC frameshift_variant&missense_variant 0.67 rifampicin
rpoC 766835 c.3466_3468delGTGinsAC frameshift_variant&missense_variant 0.73 rifampicin
rpoC 766843 c.3474T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 766867 c.3498C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rplC 800648 c.-161A>G upstream_gene_variant 0.76 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.76 linezolid
rplC 800672 c.-137G>C upstream_gene_variant 0.7 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 0.72 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.72 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 0.72 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.75 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.77 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.77 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.77 linezolid
rplC 800726 c.-83G>C upstream_gene_variant 0.77 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 0.76 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.78 linezolid
rplC 800780 c.-29C>G upstream_gene_variant 0.7 linezolid
rplC 800786 c.-23C>T upstream_gene_variant 0.57 linezolid
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471927 n.82_85delTTCGinsAGCTTGCT non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183_188delACGGGAinsG non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472037 n.192A>T non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472038 n.193_194insTA non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472041 n.196C>G non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472042 n.197_198insG non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472045 n.200T>C non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472054 n.210_212delCGC non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472062 n.217G>T non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472068 n.223T>C non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472069 n.224G>A non_coding_transcript_exon_variant 0.89 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472123 n.278A>G non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472279 n.434T>C non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472298 n.453_470delGTCCGGGTTCTCTCGGATinsCTGTTG non_coding_transcript_exon_variant 0.6 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472298 n.453_470delGTCCGGGTTCTCTCGGATinsCTTTTG non_coding_transcript_exon_variant 0.4 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472330 n.485G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472485 n.640delGinsTA non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472674 n.829T>A non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472675 n.832delC non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472837 n.992C>G non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472838 n.993A>G non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472844 n.999_1000insCG non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472847 n.1004_1005delCT non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472851 n.1006A>G non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472856 n.1011T>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin
amikacin Uncertain significance
rrs 1472858 n.1013G>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472860 n.1015C>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472861 n.1016G>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472869 n.1024G>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472873 n.1028C>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472875 n.1031delG non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472880 n.1035delGinsTCA non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473089 n.1244A>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473109 n.1264T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473286 n.1441_1442delCCinsA non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473292 n.1447G>T non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473293 n.1448G>T non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473679 n.22T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>A non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1473698 n.42dupA non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1473728 n.71A>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1473743 n.86C>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473905 n.248T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474182 n.525C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.529delA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474200 n.545delT non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474289 n.632C>T non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474487 n.830G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474497 n.840G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474517 n.860C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474695 n.1038A>C non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060_1061insGTGAG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096_1097delACinsG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474774 n.1117A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474798 n.1141C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474825 n.1168G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474921 n.1264C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474951 n.1294C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474954 n.1297A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474959 n.1302C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474963 n.1306G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474971 n.1314T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474974 n.1317G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475060 n.1404delC non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475063 n.1406A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475065 n.1408G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475067 n.1410A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475094 n.1437C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475108 n.1451C>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475111 n.1454G>A non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475119 n.1462C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475137 n.1480A>G non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475458 n.1801C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475478 n.1821_1822delGCinsTGT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475485 n.1828C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475486 n.1829A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475499 n.1842C>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475500 n.1843A>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475542 n.1885A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475696 n.2039T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475699 n.2042delCinsGT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475703 n.2046A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475757 n.2100_2101insG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1475765 n.2108A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475768 n.2111G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476087 n.2430C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476091 n.2434_2435insG non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476100 n.2443A>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476524 n.2867_2868delCAinsT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>G non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476595 n.2938C>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476600 n.2943A>C non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1476602 n.2945G>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833643 c.102C>T synonymous_variant 0.33 pyrazinamide
rpsA 1833646 c.105T>C synonymous_variant 0.41 pyrazinamide Not assoc w R - Interim
rpsA 1833649 c.108C>T synonymous_variant 0.45 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.47 pyrazinamide
rpsA 1833668 p.Ile43Val missense_variant 0.48 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.52 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 0.52 pyrazinamide
rpsA 1833684 p.Arg48His missense_variant 0.52 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.57 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.59 pyrazinamide
rpsA 1833700 c.159C>G synonymous_variant 0.59 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.69 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.72 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.72 pyrazinamide
rpsA 1833739 c.198C>T synonymous_variant 0.74 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.74 pyrazinamide
rpsA 1833769 c.228C>T synonymous_variant 0.7 pyrazinamide
rpsA 1833770 p.Asn77Asp missense_variant 0.7 pyrazinamide
rpsA 1833778 c.237C>T synonymous_variant 0.71 pyrazinamide
rpsA 1833781 c.240T>C synonymous_variant 0.65 pyrazinamide
rpsA 1833782 p.Ser81Glu missense_variant 0.68 pyrazinamide
rpsA 1833787 c.246C>T synonymous_variant 0.7 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.7 pyrazinamide
rpsA 1833797 p.Val86Ile missense_variant 0.7 pyrazinamide Uncertain significance
rpsA 1833802 p.Glu87Asp missense_variant 0.74 pyrazinamide
rpsA 1833805 c.264C>G synonymous_variant 0.76 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.78 pyrazinamide
rpsA 1833817 c.276C>G synonymous_variant 0.8 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.82 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.86 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.88 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.85 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.86 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.87 pyrazinamide
rpsA 1833862 c.321G>C synonymous_variant 0.88 pyrazinamide
rpsA 1833877 c.336C>G synonymous_variant 0.88 pyrazinamide
rpsA 1833883 c.342C>T synonymous_variant 0.9 pyrazinamide
rpsA 1833884 c.343_345delACCinsGG frameshift_variant&missense_variant 0.9 pyrazinamide Uncertain significance
rpsA 1833894 p.Ala118Glu missense_variant 0.91 pyrazinamide
rpsA 1833914 c.373_375delGCCinsCG frameshift_variant&missense_variant 0.95 pyrazinamide Uncertain significance
rpsA 1833921 p.Lys127Thr missense_variant 0.93 pyrazinamide
rpsA 1833925 c.384C>T synonymous_variant 0.93 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.92 pyrazinamide
rpsA 1833952 c.411C>T synonymous_variant 0.94 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 0.94 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.89 pyrazinamide
rpsA 1833973 c.432G>C synonymous_variant 0.88 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.87 pyrazinamide
rpsA 1833985 c.444G>C synonymous_variant 0.92 pyrazinamide
rpsA 1833997 c.456G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.93 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.93 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834024 c.483G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.94 pyrazinamide
rpsA 1834040 p.Lys167Gln missense_variant 0.94 pyrazinamide
rpsA 1834076 p.Asn179His missense_variant 0.9 pyrazinamide
rpsA 1834093 c.552G>C synonymous_variant 0.9 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.79 pyrazinamide
rpsA 1834105 c.564C>T synonymous_variant 0.79 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.79 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 0.79 pyrazinamide
rpsA 1834135 c.594G>C synonymous_variant 0.67 pyrazinamide
rpsA 1834183 c.642T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
rpsA 1834195 c.654G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834243 c.702G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834298 p.Gln253Thr missense_variant 0.94 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.91 pyrazinamide
rpsA 1834318 c.777C>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834327 c.786G>T synonymous_variant 0.97 pyrazinamide
rpsA 1834340 p.Met267Leu missense_variant 0.93 pyrazinamide Uncertain significance
rpsA 1834348 c.807T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1834354 c.813G>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834360 c.819G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1834369 c.828C>G synonymous_variant 0.86 pyrazinamide
rpsA 1834378 c.837T>G synonymous_variant 0.93 pyrazinamide
rpsA 1834384 c.843A>G synonymous_variant 0.84 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.87 pyrazinamide
rpsA 1834397 p.His286Val missense_variant 0.94 pyrazinamide
rpsA 1834408 c.867C>G synonymous_variant 0.9 pyrazinamide
rpsA 1834411 c.870T>G synonymous_variant 0.97 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.9 pyrazinamide
rpsA 1834432 c.891G>C synonymous_variant 0.84 pyrazinamide
rpsA 1834447 c.906C>G synonymous_variant 0.85 pyrazinamide
rpsA 1834451 c.910_912delTTGinsCC frameshift_variant&missense_variant 0.91 pyrazinamide Uncertain significance
rpsA 1834456 c.915T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.91 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.92 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834501 c.960G>C synonymous_variant 0.91 pyrazinamide
rpsA 1834519 c.978G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834528 c.987T>G synonymous_variant 0.97 pyrazinamide
rpsA 1834534 c.993C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834537 p.Glu332Asp missense_variant 0.96 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.96 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834552 c.1011G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834556 p.Ala339Thr missense_variant 0.96 pyrazinamide Uncertain significance
rpsA 1834565 c.1024_1026delGACinsCG frameshift_variant&missense_variant 0.97 pyrazinamide Uncertain significance
rpsA 1834600 c.1059G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834624 c.1083G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.96 pyrazinamide
rpsA 1834636 c.1095C>G synonymous_variant 0.96 pyrazinamide
rpsA 1834637 c.1096_1098delAATinsGC frameshift_variant&missense_variant 0.96 pyrazinamide Uncertain significance
rpsA 1834666 c.1125G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 1.0 pyrazinamide
rpsA 1834688 c.1147_1149delAGTinsTCC synonymous_variant 1.0 pyrazinamide
Rv2477c 2782443 p.Glu534Lys missense_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782451 p.Ala531Asp missense_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782453 p.Gly530Glu missense_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782482 p.Lys521Gln missense_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782484 p.Ala520Gly missense_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782488 c.1552_1554delAAC conservative_inframe_deletion 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782493 p.Asp517Ala missense_variant 0.94 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782496 p.Asp516Val missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782500 p.Asp515Asn missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 0.94 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782513 c.1530G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782531 c.1512C>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782558 c.1485T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782561 c.1482G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782570 c.1473C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
clpC1 4038554 c.2149_2151delATCinsGG frameshift_variant&missense_variant 0.6 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.62 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.62 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.74 pyrazinamide
clpC1 4038719 c.1986G>C synonymous_variant 0.76 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.88 pyrazinamide
clpC1 4038743 p.Thr654Val missense_variant 0.88 pyrazinamide
clpC1 4038749 c.1956C>G synonymous_variant 0.91 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 0.91 pyrazinamide
clpC1 4038767 c.1938G>T synonymous_variant 0.93 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.93 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.94 pyrazinamide
clpC1 4038788 c.1917G>C synonymous_variant 0.95 pyrazinamide
clpC1 4038791 c.1914G>C synonymous_variant 0.95 pyrazinamide
clpC1 4038794 p.Ser637Thr missense_variant 0.95 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038836 c.1869G>C synonymous_variant 0.98 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.98 pyrazinamide
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 0.98 pyrazinamide
clpC1 4038860 c.1845G>T synonymous_variant 0.98 pyrazinamide
clpC1 4038863 c.1842G>C synonymous_variant 0.98 pyrazinamide
clpC1 4038872 c.1833C>G synonymous_variant 0.96 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4038890 p.Glu605Asp missense_variant 0.95 pyrazinamide
clpC1 4038905 c.1800A>G synonymous_variant 0.94 pyrazinamide
clpC1 4038911 c.1794G>C synonymous_variant 0.94 pyrazinamide
clpC1 4038923 c.1782A>C synonymous_variant 0.92 pyrazinamide
clpC1 4038926 c.1779G>T synonymous_variant 0.91 pyrazinamide
clpC1 4038929 c.1776G>C synonymous_variant 0.95 pyrazinamide
clpC1 4038932 c.1773G>C synonymous_variant 0.95 pyrazinamide
clpC1 4038935 c.1770C>G synonymous_variant 0.95 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.95 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039586 c.1119G>C synonymous_variant 0.84 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039639 p.Ile356Val missense_variant 0.97 pyrazinamide
clpC1 4039645 p.His354Asp missense_variant 0.97 pyrazinamide
clpC1 4039654 p.Thr351Ser missense_variant 0.97 pyrazinamide
clpC1 4039661 p.Gly348Pro missense_variant 1.0 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039673 c.1032G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039691 c.1014G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039714 p.Tyr331His missense_variant 0.96 pyrazinamide
clpC1 4039718 c.987C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.91 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.69 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.82 pyrazinamide
clpC1 4039871 p.Thr278Gln missense_variant 0.82 pyrazinamide
clpC1 4040291 c.414G>C synonymous_variant 0.79 pyrazinamide
clpC1 4040300 c.405C>G synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4040311 p.Thr132Ser missense_variant 0.65 pyrazinamide
clpC1 4040312 c.393G>C synonymous_variant 0.65 pyrazinamide
clpC1 4040315 p.Glu130Asp missense_variant 0.65 pyrazinamide
clpC1 4040318 c.387C>G synonymous_variant 0.65 pyrazinamide
clpC1 4040321 c.384C>G synonymous_variant 0.65 pyrazinamide
clpC1 4040324 c.381G>C synonymous_variant 0.65 pyrazinamide
clpC1 4040333 c.372G>C synonymous_variant 0.58 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.62 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.47 pyrazinamide
clpC1 4040363 c.342A>C synonymous_variant 0.58 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 0.59 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.59 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.56 pyrazinamide