TB-Profiler result

Run: SRR12708419
Summary

Run ID: SRR12708419

Sample name:

Date: 2024-10-04T18:08:56.716292

Number of reads: 305648

Percentage reads mapped: 29.54

Median coverage: 8.0

Strain: lineage4.3.3

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.3 Euro-American (LAM) None 1.0
lineage4 Euro-American None 1.0
lineage4.3.3 Euro-American (LAM) RD115 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.Met306Val Assoc w R
pyrazinamide pncA p.Val139Gly Assoc w R
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
pncA 2288826 p.Val139Gly missense_variant 1.0 pyrazinamide Assoc w R
embB 4247429 p.Met306Val missense_variant 1.0 ethambutol Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 660 c.660G>C synonymous_variant 0.33 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>C synonymous_variant 0.32 isoniazid
dnaA 666 c.666C>G synonymous_variant 0.33 isoniazid
dnaA 675 c.675C>G synonymous_variant 0.32 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 0.32 isoniazid Not assoc w R - Interim
dnaA 681 c.681G>T synonymous_variant 0.3 isoniazid
dnaA 682 c.682_684delTTGinsCTC synonymous_variant 0.3 isoniazid
dnaA 687 c.687C>T synonymous_variant 0.3 isoniazid
dnaA 693 c.693A>C synonymous_variant 0.32 isoniazid
dnaA 705 c.705A>G synonymous_variant 0.37 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.4 isoniazid
dnaA 714 c.714C>T synonymous_variant 0.43 isoniazid
dnaA 720 c.720G>A synonymous_variant 0.48 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.39 isoniazid
dnaA 888 c.888C>G synonymous_variant 0.33 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.37 isoniazid
dnaA 903 c.903C>G synonymous_variant 0.35 isoniazid Not assoc w R - Interim
dnaA 909 c.909A>C synonymous_variant 0.35 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 0.33 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.33 isoniazid
dnaA 924 c.924C>G synonymous_variant 0.33 isoniazid
dnaA 928 p.Gln310Gly missense_variant 0.33 isoniazid
dnaA 933 c.933C>G synonymous_variant 0.35 isoniazid
gyrA 6673 c.-629A>C upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrA 6739 c.-563C>T upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6754 c.-548C>T upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6772 c.1533C>G synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 0.44 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrA 6982 c.-320A>G upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.39 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 8903 c.1602T>C synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8942 c.1641G>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8946 c.1645T>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Lys missense_variant 0.47 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.47 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9018 p.Gln573Lys missense_variant 0.4 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
nusG 734460 c.207G>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
nusG 734532 c.279A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.5 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760674 c.868T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760934 c.1128C>T synonymous_variant 0.57 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 0.64 rifampicin
rpoB 760961 c.1155C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.91 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.88 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.72 rifampicin
rpoB 761171 c.1365C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761204 c.1398C>G synonymous_variant 0.67 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.43 rifampicin Uncertain significance
rpoB 762158 c.2352G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762194 c.2388G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 762275 c.2469C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.35 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.32 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.3 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.3 rifampicin
rpoB 762881 p.Met1025Ile missense_variant 0.39 rifampicin
rpoB 762899 c.3093G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 762917 c.-453C>T upstream_gene_variant 0.44 rifampicin
rpoB 762920 c.3114C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 762947 c.-423C>G upstream_gene_variant 0.39 rifampicin
rpoC 762956 c.-414G>C upstream_gene_variant 0.39 rifampicin
rpoB 762959 c.3153G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 763052 c.-318G>C upstream_gene_variant 0.39 rifampicin
rpoB 763053 c.3247T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 763074 p.Thr1090Val missense_variant 0.41 rifampicin
rpoB 763082 c.3276C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 763172 c.3366G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 763507 c.138G>C synonymous_variant 0.47 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763531 c.162G>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>G synonymous_variant 0.55 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 763642 c.273G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763657 c.288G>A synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.37 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.33 rifampicin
rpoC 763708 c.339G>T synonymous_variant 0.47 rifampicin
rpoC 763711 c.342G>C synonymous_variant 0.33 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.8 rifampicin
rpoC 763732 c.363C>A synonymous_variant 0.34 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.48 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.82 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.79 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.73 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.68 rifampicin
rpoC 763781 p.Ser138Ala missense_variant 0.65 rifampicin
rpoC 763786 c.417C>G synonymous_variant 0.47 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.59 rifampicin
rpoC 763796 p.Met143Leu missense_variant 0.6 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764020 c.651C>T synonymous_variant 0.32 rifampicin
rpoC 764023 c.654G>T synonymous_variant 0.3 rifampicin
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 0.6 rifampicin
rpoC 764039 c.670_671delAGinsTC synonymous_variant 0.32 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.57 rifampicin
rpoC 764062 c.693C>G synonymous_variant 0.32 rifampicin
rpoC 764071 c.702G>C synonymous_variant 0.26 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764128 c.759C>G synonymous_variant 0.37 rifampicin
rpoC 764134 c.765C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764149 c.780G>C synonymous_variant 0.59 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.48 rifampicin
rpoC 764164 p.Ile265Met missense_variant 0.5 rifampicin
rpoC 764169 p.Asn267Thr missense_variant 0.53 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 0.59 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764203 c.834G>C synonymous_variant 0.61 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.61 rifampicin
rpoC 764207 p.Val280Thr missense_variant 0.61 rifampicin Uncertain significance
rpoC 764215 c.846A>C synonymous_variant 0.65 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.69 rifampicin
rpoC 764239 c.870T>C synonymous_variant 0.65 rifampicin
rpoC 764387 c.1018T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764428 c.1059G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.75 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764534 c.1165C>A synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764542 c.1173C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764545 c.1176C>A synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764560 c.1191T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764602 c.1233C>T synonymous_variant 0.45 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764623 c.1254C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764662 c.1293G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764692 c.1323C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764707 c.1338G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764755 c.1386C>T synonymous_variant 0.56 rifampicin
rpoC 764758 c.1389C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 764780 c.1411_1413delAGCinsTCG synonymous_variant 0.54 rifampicin
rpoC 764797 c.1428G>C synonymous_variant 0.54 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.76 rifampicin Not assoc w R
rpoC 764810 p.Pro481Ala missense_variant 0.76 rifampicin Uncertain significance
rpoC 764815 c.1446A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.54 rifampicin Not assoc w R
rpoC 765875 p.Val836Ile missense_variant 0.4 rifampicin Uncertain significance
rpoC 765907 c.2538G>T synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 765910 c.2541G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 766345 c.2976T>C synonymous_variant 0.67 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 0.5 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.67 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.67 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.62 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 766435 p.Glu1022Asp missense_variant 0.55 rifampicin Uncertain significance
rpoC 766540 p.Asp1057Glu missense_variant 0.5 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.55 rifampicin
rpoC 766978 c.3609C>A synonymous_variant 0.44 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 767017 c.3648C>G synonymous_variant 0.36 rifampicin
rpoC 767035 c.3666G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>T synonymous_variant 0.45 rifampicin
rpoC 767074 c.3705T>C synonymous_variant 0.45 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Thr missense_variant 0.54 rifampicin
rpsL 781766 c.207C>T synonymous_variant 0.5 streptomycin Not assoc w R - Interim
rpsL 781802 c.243G>C synonymous_variant 0.59 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.65 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.61 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.7 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.72 streptomycin Not assoc w R - Interim
rpsL 781865 c.306G>C synonymous_variant 0.38 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.72 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.72 streptomycin
rpsL 781877 c.318T>A synonymous_variant 0.37 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.69 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.65 streptomycin
rpsL 781901 c.342C>T synonymous_variant 0.26 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.67 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.56 streptomycin Uncertain significance
rrs 1471918 n.73A>T non_coding_transcript_exon_variant 0.47 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.67 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.67 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.67 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.67 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471938 n.93T>A non_coding_transcript_exon_variant 0.5 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471997 n.152T>C non_coding_transcript_exon_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472027 n.182C>T non_coding_transcript_exon_variant 0.61 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472028 n.183A>G non_coding_transcript_exon_variant 0.63 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.63 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.63 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.67 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.65 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.64 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472057 n.212C>A non_coding_transcript_exon_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472062 n.217G>T non_coding_transcript_exon_variant 0.61 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472068 n.223T>C non_coding_transcript_exon_variant 0.59 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472069 n.224G>A non_coding_transcript_exon_variant 0.6 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.62 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.7 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.7 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.68 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.76 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.67 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.73 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.57 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.57 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.57 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.62 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472313 n.468delGinsCA non_coding_transcript_exon_variant 0.53 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.52 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.52 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.52 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.55 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.47 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.44 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.45 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 0.48 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.59 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.48 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472449 n.604C>A non_coding_transcript_exon_variant 0.48 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.48 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.59 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472456 n.611T>C non_coding_transcript_exon_variant 0.47 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472463 n.618G>T non_coding_transcript_exon_variant 0.45 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.62 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472467 n.622G>T non_coding_transcript_exon_variant 0.47 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.49 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.56 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472495 n.650C>T non_coding_transcript_exon_variant 0.58 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472497 n.652G>T non_coding_transcript_exon_variant 0.57 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.6 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472580 n.735C>A non_coding_transcript_exon_variant 0.7 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472582 n.737G>A non_coding_transcript_exon_variant 0.72 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.86 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.76 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.76 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.73 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.73 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.76 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.77 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.16 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 0.3 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472860 n.1015C>T non_coding_transcript_exon_variant 0.38 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472861 n.1016G>A non_coding_transcript_exon_variant 0.38 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472873 n.1028C>T non_coding_transcript_exon_variant 0.25 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 0.26 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.29 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.82 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.82 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.64 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.17 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.17 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.17 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.17 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.68 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.88 kanamycin Not assoc w R
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473026 n.1181T>C non_coding_transcript_exon_variant 0.74 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.89 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.74 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.87 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.16 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.18 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.7 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.8 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.78 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.65 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>G non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1473673 n.16G>A non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1473677 n.20C>T non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1473679 n.22T>C non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid
rrl 1473698 n.41G>A non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473757 n.100T>G non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>A non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473768 n.111A>G non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1473833 n.176_177insT non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474153 n.496C>T non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474166 n.509G>A non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474740 n.1083G>C non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474743 n.1086T>G non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid
rrl 1474747 n.1090C>G non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>A non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474904 n.1247G>T non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475061 n.1404_1408delCAAGGinsAAGA non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1475067 n.1410A>G non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475113 n.1456C>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475202 n.1545G>C non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>A non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid
rrl 1475422 n.1765A>G non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475430 n.1773T>A non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1475443 n.1786G>A non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475475 n.1818C>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475481 n.1824C>G non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475482 n.1825A>G non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1475761 n.2104_2108delCGCAAinsACTTCG non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.68 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 0.61 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.7 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.7 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.68 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.16 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.65 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>A non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.65 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476524 n.2867delCinsGA non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.84 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.83 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.52 capreomycin
linezolid
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.82 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476665 n.3008T>G non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476666 n.3009C>T non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476675 n.3018C>G non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833676 c.135A>G synonymous_variant 0.67 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 0.64 pyrazinamide
rpsA 1833685 c.144G>C synonymous_variant 0.82 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.69 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.69 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.75 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.73 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.73 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.74 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.74 pyrazinamide
rpsA 1833781 c.240T>C synonymous_variant 0.57 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.62 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.6 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.48 pyrazinamide
rpsA 1833805 c.264C>T synonymous_variant 0.38 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.35 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.47 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.57 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.59 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.56 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.56 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.79 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.41 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 0.44 pyrazinamide
rpsA 1833961 c.420C>G synonymous_variant 0.36 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.48 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.35 pyrazinamide
rpsA 1833973 c.432G>C synonymous_variant 0.5 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.81 pyrazinamide
rpsA 1833985 c.444G>C synonymous_variant 0.5 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.81 pyrazinamide
rpsA 1833997 c.456G>C synonymous_variant 0.45 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.79 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.76 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.75 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.75 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.66 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.67 pyrazinamide
rpsA 1834033 c.492C>T synonymous_variant 0.29 pyrazinamide
rpsA 1834034 p.Ile165Val missense_variant 0.33 pyrazinamide
rpsA 1834054 c.513C>G synonymous_variant 0.36 pyrazinamide
rpsA 1834327 c.786G>T synonymous_variant 0.71 pyrazinamide
rpsA 1834357 c.816T>C synonymous_variant 0.75 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>C synonymous_variant 0.47 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.44 pyrazinamide
rpsA 1834411 c.870T>G synonymous_variant 0.37 pyrazinamide
rpsA 1834414 c.873C>T synonymous_variant 0.37 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.37 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.39 pyrazinamide
rpsA 1834429 c.888C>T synonymous_variant 0.37 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.71 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.71 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.71 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 0.41 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.53 pyrazinamide
rpsA 1834627 c.1086C>G synonymous_variant 0.4 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.52 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.59 pyrazinamide
rpsA 1834650 p.Thr370Ser missense_variant 0.46 pyrazinamide
rpsA 1834653 p.Glu371Ala missense_variant 0.46 pyrazinamide
rpsA 1834663 c.1122C>T synonymous_variant 0.46 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.65 pyrazinamide
rpsA 1834688 c.1147_1149delAGTinsTCG synonymous_variant 0.53 pyrazinamide
rpsA 1834699 p.Glu386Asp missense_variant 0.64 pyrazinamide
rpsA 1834712 p.Ile391Val missense_variant 0.56 pyrazinamide Uncertain significance
rpsA 1834732 c.1191T>C synonymous_variant 0.76 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.5 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.79 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.81 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.82 pyrazinamide
rpsA 1834774 c.1233C>T synonymous_variant 0.73 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 0.73 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.62 pyrazinamide
rpsA 1834813 c.1272G>T synonymous_variant 0.54 pyrazinamide
kasA 2517917 c.-198G>C upstream_gene_variant 0.32 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.43 isoniazid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
mtrB 3625065 p.Met517Leu missense_variant 1.0 rifampicin Not assoc w R
bedaquiline Uncertain significance
mtrB 3626704 c.-91C>T upstream_gene_variant 0.46 rifampicin
bedaquiline
mtrB 3626711 c.-98T>C upstream_gene_variant 0.46 rifampicin
bedaquiline
mtrB 3626717 c.-104C>T upstream_gene_variant 0.46 rifampicin
bedaquiline
mtrB 3626732 c.-119A>G upstream_gene_variant 0.5 rifampicin
bedaquiline
mtrA 3626741 c.609C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626756 c.594C>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626759 c.591T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626762 c.588G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626786 c.564A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626792 c.558G>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
bedaquiline
rpoA 3877656 c.852T>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3877665 c.843C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoA 3877734 c.774G>C synonymous_variant 0.59 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.56 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoA 3877752 p.Asp252Glu missense_variant 0.59 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoA 3877797 c.711G>A synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoA 3877896 c.612G>A synonymous_variant 0.43 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoA 3877929 p.Ile193Val missense_variant 0.42 rifampicin Uncertain significance
rpoA 3877962 c.546G>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoA 3878130 c.378C>G synonymous_variant 0.48 rifampicin
rpoA 3878142 p.Gly122Asp missense_variant 0.45 rifampicin Uncertain significance
rpoA 3878160 c.348C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoA 3878196 p.Glu104Ala missense_variant 0.35 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoA 3878343 c.165C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.5 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.44 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.47 rifampicin
clpC1 4039070 c.1635G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.75 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.71 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.73 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.71 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.71 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.64 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.71 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.69 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.69 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.69 pyrazinamide
clpC1 4039478 c.1227G>C synonymous_variant 0.69 pyrazinamide
clpC1 4039499 c.1206G>C synonymous_variant 0.5 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.55 pyrazinamide
clpC1 4039522 c.1183C>T synonymous_variant 0.25 pyrazinamide
clpC1 4039528 c.1177C>A synonymous_variant 0.29 pyrazinamide
clpC1 4039541 c.1164C>G synonymous_variant 0.84 pyrazinamide
clpC1 4039544 c.1161C>T synonymous_variant 0.83 pyrazinamide
clpC1 4039547 c.1158C>G synonymous_variant 0.42 pyrazinamide
clpC1 4039553 c.1152C>G synonymous_variant 0.43 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.43 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.4 pyrazinamide
clpC1 4039565 c.1140G>T synonymous_variant 0.4 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.43 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.83 pyrazinamide Uncertain significance
clpC1 4039571 c.1134G>A synonymous_variant 0.38 pyrazinamide
clpC1 4039574 p.Ala377Ser missense_variant 0.83 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.45 pyrazinamide Not assoc w R - Interim
clpC1 4039586 c.1119G>C synonymous_variant 0.82 pyrazinamide
clpC1 4039589 c.1116G>C synonymous_variant 0.4 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 0.4 pyrazinamide
clpC1 4039601 c.1104G>A synonymous_variant 0.33 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.32 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.78 pyrazinamide
clpC1 4039619 c.1086G>A synonymous_variant 0.33 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.36 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.57 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.58 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.66 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.66 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.66 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.66 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.69 pyrazinamide
clpC1 4039763 c.942C>T synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
clpC1 4039769 c.936C>G synonymous_variant 0.72 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.71 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.3 pyrazinamide
clpC1 4039814 c.891C>G synonymous_variant 0.38 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.39 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.78 pyrazinamide
clpC1 4039823 c.882T>C synonymous_variant 0.36 pyrazinamide Not assoc w R - Interim
clpC1 4039826 c.879C>G synonymous_variant 0.39 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.34 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.41 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.85 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.47 pyrazinamide
clpC1 4039868 c.837C>T synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4039898 c.807C>G synonymous_variant 0.49 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.48 pyrazinamide
clpC1 4039907 c.798G>A synonymous_variant 0.45 pyrazinamide Not assoc w R - Interim
clpC1 4039913 c.792C>T synonymous_variant 0.3 pyrazinamide
clpC1 4039925 c.780C>G synonymous_variant 0.48 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.74 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.74 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.53 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.51 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.73 pyrazinamide
clpC1 4039955 p.Leu250Phe missense_variant 0.55 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.75 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 0.5 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.5 pyrazinamide
clpC1 4040009 c.696C>G synonymous_variant 0.27 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 0.24 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 0.36 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.68 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.74 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 0.62 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.59 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4040429 c.274_276delTTGinsCTC synonymous_variant 0.47 pyrazinamide
clpC1 4040435 c.270G>C synonymous_variant 0.44 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4040456 c.249C>T synonymous_variant 0.72 pyrazinamide Not assoc w R - Interim
clpC1 4040462 c.243C>G synonymous_variant 0.64 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.74 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4040522 c.183T>C synonymous_variant 0.52 pyrazinamide Not assoc w R - Interim