TB-Profiler result

Run: SRR9971150
Summary

Run ID: SRR9971150

Sample name:

Date: 2024-04-15T15:31:01.659841

Number of reads: 3244093

Percentage reads mapped: 63.3

Median coverage: 79.0

Strain: lineage4.8.1

Spoligotype:

Drug-resistance: RR-TB

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.8 Euro-American (mainly T) RD219 1.0
lineage4.8.1 Euro-American (mainly T) RD219 0.97
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB p.Leu430Pro Assoc w R
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpoB 761095 p.Leu430Pro missense_variant 0.71 rifampicin Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 8968 p.Ala556Gly missense_variant 0.12 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.13 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.13 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9018 p.Gln573Lys missense_variant 0.15 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>T synonymous_variant 0.16 levofloxacin
moxifloxacin
gyrA 9029 c.1728T>G synonymous_variant 0.15 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.14 levofloxacin
moxifloxacin
gyrA 9044 c.1743C>G synonymous_variant 0.13 levofloxacin
moxifloxacin
nusG 734505 c.252G>T synonymous_variant 0.17 rifampicin
rpoB 760094 c.288G>C synonymous_variant 0.26 rifampicin
rpoB 760101 c.295T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>C synonymous_variant 0.3 rifampicin
rpoB 760112 c.306T>G synonymous_variant 0.3 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.31 rifampicin Uncertain significance
rpoB 760139 c.333A>C synonymous_variant 0.31 rifampicin
rpoB 760140 c.334_336delCCCinsTG frameshift_variant&missense_variant 0.3 rifampicin
rpoB 760172 c.366G>C synonymous_variant 0.37 rifampicin
rpoB 760181 c.375T>G synonymous_variant 0.39 rifampicin
rpoB 760184 c.378A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 760185 c.379C>T synonymous_variant 0.41 rifampicin
rpoB 760199 c.393C>G synonymous_variant 0.39 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 760274 p.Glu156Asp missense_variant 0.37 rifampicin Uncertain significance
rpoB 760283 c.477G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.27 rifampicin
rpoB 760313 c.507G>C synonymous_variant 0.26 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.22 rifampicin
rpoB 760317 c.511_512delAGinsTC synonymous_variant 0.22 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.22 rifampicin
rpoB 760331 c.525G>T synonymous_variant 0.21 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.22 rifampicin
rpoB 760340 c.534G>C synonymous_variant 0.22 rifampicin
rpoB 760355 p.Glu183Asp missense_variant 0.24 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760368 c.562_563delTCinsAG synonymous_variant 0.22 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.21 rifampicin Uncertain significance
rpoB 760382 c.576G>C synonymous_variant 0.18 rifampicin
rpoB 760400 c.594G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760407 p.Ser201Gly missense_variant 0.14 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.19 rifampicin
rpoB 760922 c.1116G>C synonymous_variant 0.19 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.19 rifampicin
rpoB 760931 c.1125C>G synonymous_variant 0.19 rifampicin
rpoB 760940 c.1134G>C synonymous_variant 0.17 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 0.15 rifampicin
rpoB 760961 c.1155C>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.15 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.16 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.22 rifampicin
rpoB 760997 c.1191G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761003 c.1197C>G synonymous_variant 0.2 rifampicin
rpoB 761006 c.1200C>T synonymous_variant 0.22 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>A synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.29 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.29 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.3 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761171 c.1365C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761204 c.1398C>G synonymous_variant 0.24 rifampicin
rpoB 761207 c.1401C>A synonymous_variant 0.25 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.26 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 0.14 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 762002 c.2196C>G synonymous_variant 0.24 rifampicin
rpoB 762003 c.2197_2199delAACinsCG frameshift_variant&missense_variant 0.25 rifampicin
rpoB 762011 c.2205G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762026 c.2220G>C synonymous_variant 0.27 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 762080 c.2274G>C synonymous_variant 0.35 rifampicin
rpoB 762086 c.2280G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.3 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.27 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.23 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.23 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 0.17 rifampicin
rpoB 762236 c.2430G>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 762251 c.2445G>C synonymous_variant 0.12 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 762881 p.Met1025Ile missense_variant 0.2 rifampicin
rpoB 762899 c.3093G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 762971 c.-399G>C upstream_gene_variant 0.2 rifampicin
rpoC 762989 c.-381G>C upstream_gene_variant 0.14 rifampicin
rpoC 763411 c.42T>C synonymous_variant 0.28 rifampicin
rpoC 763414 c.45T>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763423 c.54G>A synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763430 c.61_63delAGGinsCC frameshift_variant&missense_variant 0.28 rifampicin
rpoC 763433 c.64_66delCAAinsAC frameshift_variant&missense_variant 0.28 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763507 c.138G>C synonymous_variant 0.39 rifampicin
rpoC 763528 c.159G>C synonymous_variant 0.33 rifampicin
rpoC 763531 c.162G>C synonymous_variant 0.34 rifampicin Not assoc w R
rpoC 763534 c.165T>C synonymous_variant 0.34 rifampicin
rpoC 763537 c.168C>G synonymous_variant 0.33 rifampicin
rpoC 763546 c.177A>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 763558 c.189C>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763624 c.255C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763642 c.273G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>T synonymous_variant 0.22 rifampicin
rpoC 763669 c.300C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 0.16 rifampicin
rpoC 763708 c.339G>T synonymous_variant 0.16 rifampicin
rpoC 763711 c.342G>C synonymous_variant 0.16 rifampicin
rpoC 763714 c.345G>T synonymous_variant 0.15 rifampicin
rpoC 763717 c.348T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.19 rifampicin
rpoC 763732 c.363C>T synonymous_variant 0.21 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.2 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.21 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 0.22 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>A synonymous_variant 0.19 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764545 c.1176C>G synonymous_variant 0.21 rifampicin
rpoC 764548 c.1179G>C synonymous_variant 0.23 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764635 c.1266C>G synonymous_variant 0.14 rifampicin
rpoC 764644 c.1275G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764647 c.1278C>T synonymous_variant 0.16 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764653 c.1284G>C synonymous_variant 0.18 rifampicin
rpoC 764662 c.1293G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764707 c.1338G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764737 c.1368G>C synonymous_variant 0.16 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764780 c.1411_1412delAGinsTC synonymous_variant 0.16 rifampicin
rpoC 764785 c.1416C>G synonymous_variant 0.16 rifampicin
rpoC 764797 c.1428G>C synonymous_variant 0.16 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.14 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.14 rifampicin
rpoC 764869 c.1500C>T synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 0.12 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 767017 c.3648C>G synonymous_variant 0.15 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781592 c.33T>C synonymous_variant 0.19 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.2 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.19 streptomycin
rpsL 781606 p.Ile16Thr missense_variant 0.2 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.2 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.18 streptomycin Not assoc w R - Interim
rpsL 781655 c.96T>C synonymous_variant 0.23 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.23 streptomycin
rpsL 781664 c.105C>T synonymous_variant 0.24 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.25 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.16 streptomycin
rpsL 781706 c.147T>G synonymous_variant 0.14 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.15 streptomycin
rpsL 781721 c.162C>T synonymous_variant 0.15 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.19 streptomycin Not assoc w R - Interim
rpsL 781802 c.243G>C synonymous_variant 0.26 streptomycin
rpsL 781805 c.246G>C synonymous_variant 0.3 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.29 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.3 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.28 streptomycin
rpsL 781832 c.273T>G synonymous_variant 0.28 streptomycin
rpsL 781856 c.297C>T synonymous_variant 0.3 streptomycin Not assoc w R - Interim
rpsL 781859 c.300T>C synonymous_variant 0.29 streptomycin Not assoc w R - Interim
rpsL 781865 c.306G>C synonymous_variant 0.29 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.29 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.3 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.32 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.3 streptomycin
rpsL 781898 c.339A>G synonymous_variant 0.28 streptomycin
rpsL 781901 c.342C>T synonymous_variant 0.28 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.28 streptomycin
rpsL 781916 c.357T>G synonymous_variant 0.3 streptomycin
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471918 n.73A>T non_coding_transcript_exon_variant 0.6 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.6 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.59 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.62 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.6 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471938 n.93T>A non_coding_transcript_exon_variant 0.64 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.46 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.77 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.87 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.86 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472312 n.467_468insA non_coding_transcript_exon_variant 0.86 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.86 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.85 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Uncertain significance
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472449 n.604C>T non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472456 n.611T>C non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 0.76 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472463 n.618G>A non_coding_transcript_exon_variant 0.76 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472467 n.622G>T non_coding_transcript_exon_variant 0.77 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.76 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.8 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 0.66 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472837 n.992C>T non_coding_transcript_exon_variant 0.64 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472840 n.995A>C non_coding_transcript_exon_variant 0.59 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>C non_coding_transcript_exon_variant 0.65 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.65 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472861 n.1016G>C non_coding_transcript_exon_variant 0.65 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472862 n.1017T>C non_coding_transcript_exon_variant 0.63 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472863 n.1018T>C non_coding_transcript_exon_variant 0.63 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472873 n.1028C>T non_coding_transcript_exon_variant 0.58 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 0.58 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472878 n.1033G>A non_coding_transcript_exon_variant 0.58 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.63 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.75 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.77 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.79 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473026 n.1181T>C non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.87 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.88 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473717 n.60G>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473757 n.100T>G non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473791 n.134A>C non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1473792 n.135C>A non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1473793 n.136G>C non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1473802 n.145C>G non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1473803 n.146G>T non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1473804 n.147T>G non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473814 n.157A>G non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>C non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473830 n.173T>C non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1473833 n.176_177insT non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230delTinsCA non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474153 n.496C>T non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1474166 n.509G>A non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474220 n.563G>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474287 n.630_631insGCGCCA non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1474292 n.636_646delTCCTCTCCGGA non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474310 n.655dupG non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756_778delACCCACACGCGCATACGCGCGTGinsTT non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1474436 n.780_782delGAA non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474638 n.981C>T non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474709 n.1052G>A non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474710 n.1053T>G non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474711 n.1054G>A non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1474716 n.1059_1060delAAinsGAG non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475060 n.1404delC non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475065 n.1408G>A non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475067 n.1410A>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475113 n.1456C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475414 n.1757G>C non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1475422 n.1765A>G non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475443 n.1786G>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475481 n.1824C>T non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1475482 n.1825A>T non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475655 n.1998T>A non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475761 n.2104C>A non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1475766 n.2109G>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.88 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>G non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1476047 n.2390G>C non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.85 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.85 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.84 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.85 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.86 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.85 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>T non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.8 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476665 n.3008T>G non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476666 n.3009C>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476675 n.3018C>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833589 c.48A>C synonymous_variant 0.23 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.24 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.24 pyrazinamide
rpsA 1833607 c.66T>C synonymous_variant 0.24 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.28 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.27 pyrazinamide
rpsA 1833623 p.Lys28Ala missense_variant 0.25 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.45 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 0.42 pyrazinamide
rpsA 1833682 c.141C>T synonymous_variant 0.42 pyrazinamide
rpsA 1833685 c.144G>C synonymous_variant 0.43 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.39 pyrazinamide
rpsA 1833697 c.156C>T synonymous_variant 0.38 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.38 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.26 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.26 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.26 pyrazinamide
rpsA 1833739 c.198C>T synonymous_variant 0.26 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.29 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.33 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.33 pyrazinamide Not assoc w R - Interim
rpsA 1833781 c.240T>C synonymous_variant 0.29 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.22 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.24 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.24 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.23 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.23 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.23 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 0.24 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.25 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.26 pyrazinamide
rpsA 1833850 c.309C>G synonymous_variant 0.28 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.32 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.33 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.37 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.41 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 0.46 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.48 pyrazinamide
rpsA 1833973 c.432G>C synonymous_variant 0.48 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.47 pyrazinamide
rpsA 1833991 c.450C>T synonymous_variant 0.47 pyrazinamide
rpsA 1833997 c.456G>C synonymous_variant 0.46 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.44 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.45 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.43 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.43 pyrazinamide
rpsA 1834024 c.483G>C synonymous_variant 0.42 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.38 pyrazinamide
rpsA 1834034 p.Ile165Val missense_variant 0.38 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.32 pyrazinamide
rpsA 1834093 c.552G>C synonymous_variant 0.25 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.23 pyrazinamide
rpsA 1834108 c.567C>A synonymous_variant 0.24 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.18 pyrazinamide
rpsA 1834474 c.933C>T synonymous_variant 0.2 pyrazinamide
rpsA 1834489 c.948T>A synonymous_variant 0.24 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.22 pyrazinamide
rpsA 1834534 c.993C>G synonymous_variant 0.22 pyrazinamide
rpsA 1834540 c.999G>T synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
rpsA 1834543 c.1002C>G synonymous_variant 0.2 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.18 pyrazinamide
rpsA 1834552 c.1011G>T synonymous_variant 0.17 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 0.17 pyrazinamide
rpsA 1834557 p.Ala339Gly missense_variant 0.17 pyrazinamide
rpsA 1834570 c.1029C>T synonymous_variant 0.23 pyrazinamide Not assoc w R - Interim
rpsA 1834574 c.1033_1035delATGinsCC frameshift_variant&missense_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 0.23 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.24 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 0.23 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.23 pyrazinamide
rpsA 1834627 c.1086C>G synonymous_variant 0.24 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.24 pyrazinamide
rpsA 1834636 c.1095C>G synonymous_variant 0.26 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.26 pyrazinamide
rpsA 1834650 p.Thr370Asn missense_variant 0.26 pyrazinamide
rpsA 1834653 p.Glu371Ala missense_variant 0.24 pyrazinamide
rpsA 1834663 c.1122C>T synonymous_variant 0.24 pyrazinamide
rpsA 1834667 c.1126_1128delGCGinsTC frameshift_variant&missense_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834688 c.1147_1149delAGTinsTCG synonymous_variant 0.27 pyrazinamide
rpsA 1834699 p.Glu386Asp missense_variant 0.3 pyrazinamide
rpsA 1834733 p.Ala398Pro missense_variant 0.16 pyrazinamide
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
PPE35 2168149 p.Pro822Ser missense_variant 1.0 pyrazinamide Not assoc w R
PPE35 2170892 c.-280G>A upstream_gene_variant 1.0 pyrazinamide
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
pncA 2288798 c.444C>G synonymous_variant 1.0 pyrazinamide
kasA 2517917 c.-198G>C upstream_gene_variant 0.25 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.27 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 0.23 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 0.2 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.21 isoniazid
kasA 2517966 c.-149_-147delGGTinsAC upstream_gene_variant 0.22 isoniazid
Rv2680 2995848 c.-257G>A upstream_gene_variant 1.0 capreomycin
fbiD 3339040 c.-78T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 0.98 ethionamide Uncertain significance
mtrB 3627059 c.-446G>C upstream_gene_variant 0.14 bedaquiline
rifampicin
mtrB 3627065 c.-452G>C upstream_gene_variant 0.14 bedaquiline
rifampicin
mtrA 3627068 c.282T>G synonymous_variant 0.13 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627071 c.-458G>C upstream_gene_variant 0.13 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 0.14 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 0.15 bedaquiline
rifampicin
mtrB 3627092 c.-479C>G upstream_gene_variant 0.15 bedaquiline
rifampicin
fbiB 3642874 p.Leu447Arg missense_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
clpC1 4038812 c.1893T>C synonymous_variant 0.2 pyrazinamide
clpC1 4038815 c.1890G>A synonymous_variant 0.19 pyrazinamide
clpC1 4038839 c.1866G>C synonymous_variant 0.23 pyrazinamide
clpC1 4038860 c.1845G>A synonymous_variant 0.25 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 0.26 pyrazinamide
clpC1 4038905 c.1800A>C synonymous_variant 0.26 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.25 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.25 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.26 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.27 pyrazinamide
clpC1 4038926 c.1779G>C synonymous_variant 0.29 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.25 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.25 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.27 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.29 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.22 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.22 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.2 pyrazinamide
clpC1 4039007 c.1698G>C synonymous_variant 0.19 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.16 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.13 pyrazinamide
clpC1 4039073 c.1632C>T synonymous_variant 0.13 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.14 pyrazinamide Not assoc w R - Interim
clpC1 4039279 p.Val476Ile missense_variant 0.14 pyrazinamide
clpC1 4039280 c.1425G>C synonymous_variant 0.13 pyrazinamide
clpC1 4039286 c.1419T>G synonymous_variant 0.13 pyrazinamide
clpC1 4039289 c.1416T>C synonymous_variant 0.14 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 0.14 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 0.14 pyrazinamide
clpC1 4039313 c.1392C>G synonymous_variant 0.15 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.14 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.14 pyrazinamide
clpC1 4039328 c.1377A>G synonymous_variant 0.13 pyrazinamide
clpC1 4039348 c.1357C>A synonymous_variant 0.12 pyrazinamide
clpC1 4039355 c.1350G>C synonymous_variant 0.12 pyrazinamide
clpC1 4039359 p.Ser449Asn missense_variant 0.13 pyrazinamide
clpC1 4039361 c.1344C>G synonymous_variant 0.13 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.16 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.17 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 0.15 pyrazinamide
clpC1 4039406 c.1299G>C synonymous_variant 0.15 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.15 pyrazinamide
clpC1 4039412 c.1293T>C synonymous_variant 0.15 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039427 p.Glu426Asp missense_variant 0.18 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 0.18 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.2 pyrazinamide
clpC1 4039448 c.1257A>G synonymous_variant 0.23 pyrazinamide Not assoc w R - Interim
clpC1 4039469 c.1236T>C synonymous_variant 0.22 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.22 pyrazinamide
clpC1 4039478 c.1227G>A synonymous_variant 0.23 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.22 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.23 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.23 pyrazinamide
clpC1 4039499 c.1206G>C synonymous_variant 0.23 pyrazinamide
clpC1 4039508 c.1197G>C synonymous_variant 0.2 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.2 pyrazinamide
clpC1 4039526 c.1179G>C synonymous_variant 0.18 pyrazinamide
clpC1 4039598 c.1107C>T synonymous_variant 0.12 pyrazinamide Not assoc w R - Interim
clpC1 4039610 c.1095G>C synonymous_variant 0.15 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.15 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.16 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.16 pyrazinamide
clpC1 4039655 c.1050G>C synonymous_variant 0.18 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.16 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.16 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.17 pyrazinamide
clpC1 4039688 c.1017G>A synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
clpC1 4039691 c.1014G>C synonymous_variant 0.18 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.18 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.21 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.17 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.17 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.15 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.13 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.13 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.15 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.15 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 0.16 pyrazinamide
clpC1 4039811 c.894C>A synonymous_variant 0.16 pyrazinamide
clpC1 4039814 c.891C>G synonymous_variant 0.16 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.17 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.18 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.18 pyrazinamide
clpC1 4039835 c.870C>T synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4039850 c.855T>C synonymous_variant 0.18 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.14 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.13 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.12 pyrazinamide
clpC1 4040411 c.294T>C synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.14 pyrazinamide Not assoc w R - Interim
clpC1 4040429 c.274_276delTTGinsCC frameshift_variant&missense_variant 0.15 pyrazinamide
clpC1 4040435 c.270G>C synonymous_variant 0.17 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
clpC1 4040456 c.249C>T synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.17 pyrazinamide
clpC1 4040462 c.243C>T synonymous_variant 0.17 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.17 pyrazinamide
clpC1 4040468 c.237G>C synonymous_variant 0.16 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>A synonymous_variant 0.21 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 0.21 pyrazinamide
clpC1 4040546 c.159G>T synonymous_variant 0.17 pyrazinamide
clpC1 4040779 c.-75C>T upstream_gene_variant 1.0 pyrazinamide
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R