TB-Profiler result

Run: SRR6789624
Summary

Run ID: SRR6789624

Sample name:

Date: 2024-04-15T17:43:19.990821

Number of reads: 406687

Percentage reads mapped: 31.05

Median coverage: 8.0

Strain: lineage4.1.1.3

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.1 Euro-American None 0.97
lineage4.1.1.3 Euro-American (X-type) RD193 0.42
lineage4 Euro-American None 1.0
lineage4.1.1 Euro-American (X-type) None 0.27
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ser315Thr Assoc w R High-level resistance
ethambutol
pyrazinamide
streptomycin rrs n.799C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
capreomycin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
kanamycin rrs n.1402C>A Uncertain significance Mutation from literature
n.1484G>T Assoc w R
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.28 streptomycin Uncertain significance Mutation from literature
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.27 kanamycin Uncertain significance Mutation from literature
capreomycin Uncertain significance Mutation from literature
amikacin Uncertain significance Mutation from literature
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.3 kanamycin Assoc w R
capreomycin Assoc w R
amikacin Assoc w R
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid Assoc w R High-level resistance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrA 7123 c.-179C>G upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7126 c.-176G>A upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7135 c.-167G>A upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7138 c.-164G>A upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7156 c.1917C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7159 c.1920C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7168 c.-134C>G upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7177 c.-125G>A upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7189 c.-113C>T upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 7424 c.123G>A synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7436 c.135C>T synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7442 c.141G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7460 c.159C>A synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.67 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 7523 c.222C>A synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 7526 c.225G>T synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7569 c.268_270delGCGinsTC frameshift_variant&missense_variant 0.64 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 0.53 levofloxacin
moxifloxacin
gyrA 7906 p.Phe202Tyr missense_variant 0.47 levofloxacin
moxifloxacin
gyrA 7911 p.Ala204Cys missense_variant 0.44 levofloxacin
moxifloxacin
gyrA 7922 c.621T>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 7928 p.Asp209Glu missense_variant 0.47 levofloxacin
moxifloxacin
gyrA 7934 c.633C>T synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 7942 p.Glu214Ala missense_variant 0.47 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
mshA 575728 c.381C>G synonymous_variant 0.32 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 0.32 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.35 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 0.47 ethionamide
isoniazid Uncertain significance
mshA 575749 c.402C>G synonymous_variant 0.47 ethionamide
isoniazid
ccsA 620613 c.723C>T synonymous_variant 0.43 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 0.37 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 0.37 capreomycin
amikacin
kanamycin
ccsA 620643 c.753C>G synonymous_variant 0.37 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 0.41 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 0.35 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 0.35 capreomycin
amikacin
kanamycin
ccsA 620703 c.813G>T synonymous_variant 0.37 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 0.32 capreomycin
amikacin
kanamycin
ccsA 620724 c.834C>T synonymous_variant 0.35 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 0.45 capreomycin
amikacin
kanamycin
ccsA 620736 c.846G>C synonymous_variant 0.35 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 0.35 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 0.35 capreomycin
amikacin
kanamycin
ccsA 620764 c.874_876delGCCinsTG frameshift_variant&missense_variant 0.32 capreomycin
amikacin
kanamycin
nusG 734451 c.198G>C synonymous_variant 0.53 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.53 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.53 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.35 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.39 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760532 c.726T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760784 c.978G>C synonymous_variant 0.47 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.54 rifampicin
rpoB 760841 c.1035T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 0.55 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760868 c.1062C>T synonymous_variant 0.55 rifampicin
rpoB 760910 c.1104C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.62 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.62 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760934 c.1128C>T synonymous_variant 0.73 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>T synonymous_variant 0.9 rifampicin
rpoB 760988 c.1182C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.81 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.76 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 762002 c.2196C>G synonymous_variant 0.43 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.58 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.64 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 0.33 rifampicin
rpoB 762863 c.3057T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762879 c.3073_3075delATGinsCC frameshift_variant&missense_variant 0.33 rifampicin
rpoC 762911 c.-459C>T upstream_gene_variant 0.35 rifampicin
rpoB 762920 c.3114C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.35 rifampicin
rpoB 762989 c.3183G>A synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763022 c.-348C>G upstream_gene_variant 0.38 rifampicin
rpoB 763053 c.3247T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 0.42 rifampicin
rpoB 763088 c.3282C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>C upstream_gene_variant 0.57 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.58 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763160 c.-210G>T upstream_gene_variant 0.56 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.5 rifampicin
rpoC 763408 c.39T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 0.58 rifampicin
rpoC 763414 c.45T>C synonymous_variant 0.58 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 0.5 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCT frameshift_variant&missense_variant 0.5 rifampicin
rpoC 763433 c.64_66delCAAinsAC frameshift_variant&missense_variant 0.5 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 0.5 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 763465 c.96G>A synonymous_variant 0.5 rifampicin
rpoC 763468 c.99G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>T synonymous_variant 0.62 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763558 c.189C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763576 c.207C>G synonymous_variant 0.74 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 763621 c.252C>G synonymous_variant 0.72 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 0.72 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.57 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 763705 c.336G>C synonymous_variant 0.57 rifampicin
rpoC 763709 c.340C>T synonymous_variant 0.57 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.52 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.47 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.45 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 763781 p.Ser138Ala missense_variant 0.41 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.38 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.45 rifampicin
rpoC 763816 c.447C>G synonymous_variant 0.5 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.44 rifampicin
rpoC 763837 c.468G>C synonymous_variant 0.44 rifampicin
rpoC 763840 c.471G>C synonymous_variant 0.47 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.43 rifampicin
rpoC 763861 c.492C>T synonymous_variant 0.45 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.47 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.47 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.43 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.58 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.58 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764297 p.Met310Leu missense_variant 0.55 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.67 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764374 c.1005C>T synonymous_variant 0.64 rifampicin
rpoC 764380 c.1011G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.85 rifampicin
rpoC 764440 c.1071G>T synonymous_variant 0.7 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 0.83 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.54 rifampicin
rpoC 764455 c.1086G>T synonymous_variant 0.54 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.6 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.76 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>C synonymous_variant 0.33 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 764623 c.1254C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764719 c.1350G>A synonymous_variant 0.45 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764780 c.1411_1413delAGCinsTCG synonymous_variant 0.23 rifampicin
rpoC 764797 c.1428G>C synonymous_variant 0.23 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.61 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764822 p.Asp485Tyr missense_variant 0.38 rifampicin Uncertain significance
rpoC 764827 c.1458G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764851 c.1482C>T synonymous_variant 0.58 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 0.6 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.73 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.56 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 765150 p.Gly594Glu missense_variant 1.0 rifampicin Not assoc w R
rpoC 765793 c.2424C>G synonymous_variant 0.6 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.6 rifampicin
rpoC 765800 p.Phe811Leu missense_variant 0.6 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>C synonymous_variant 0.6 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 0.64 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 765868 c.2499G>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 0.54 rifampicin
rpoC 765875 p.Val836Ile missense_variant 0.54 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.5 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765895 c.2526G>A synonymous_variant 0.5 rifampicin
rpoC 765899 c.2530C>T synonymous_variant 0.5 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 0.59 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 0.46 rifampicin
rpoC 765937 c.2568T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.5 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.58 rifampicin
rpoC 765961 c.2592G>T synonymous_variant 0.58 rifampicin
rpoC 765962 c.2593T>C synonymous_variant 0.58 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 766381 c.3012C>T synonymous_variant 0.6 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.67 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 0.55 rifampicin
rpoC 766428 c.3059_3060insTAC disruptive_inframe_insertion 0.55 rifampicin
rpoC 766433 c.3065delA frameshift_variant 0.55 rifampicin
rpoC 766442 p.Thr1025Val missense_variant 0.54 rifampicin
rpoC 766456 c.3087C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 766459 c.3090G>C synonymous_variant 0.5 rifampicin
rpoC 766483 c.3114G>T synonymous_variant 0.38 rifampicin
rpoC 766484 c.3115_3117delGTAinsAT frameshift_variant&missense_variant 0.38 rifampicin
rpoC 766492 c.3123T>G synonymous_variant 0.43 rifampicin
rpoC 766493 p.Gly1042Asn missense_variant 0.43 rifampicin
rpoC 766504 c.3135G>C synonymous_variant 0.43 rifampicin
rpoC 766517 c.3148_3150delACCinsGG frameshift_variant&missense_variant 0.38 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.38 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 0.46 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 0.6 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.5 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 0.54 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 0.58 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 0.58 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.58 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 0.42 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>T synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 767143 c.3774C>T synonymous_variant 0.47 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781435 c.-125G>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781901 c.342C>T synonymous_variant 0.24 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.24 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.23 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.29 streptomycin Uncertain significance
rplC 800219 c.-590T>C upstream_gene_variant 1.0 linezolid
fbiC 1304742 c.1812T>C synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>T synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1304760 c.1830G>C synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>G synonymous_variant 0.32 clofazimine
pretomanid
delamanid
atpE 1461170 c.126A>G synonymous_variant 0.46 bedaquiline
atpE 1461179 c.135G>C synonymous_variant 0.46 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.46 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.46 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 0.46 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.55 bedaquiline
atpE 1461224 c.180T>G synonymous_variant 0.55 bedaquiline
rrs 1471866 n.21C>T non_coding_transcript_exon_variant 0.29 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472028 n.183A>G non_coding_transcript_exon_variant 0.62 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.53 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472032 n.187G>A non_coding_transcript_exon_variant 0.57 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.55 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.52 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472037 n.192A>C non_coding_transcript_exon_variant 0.52 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.53 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.65 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.61 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.76 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.72 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.61 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.2 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.64 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.26 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.49 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472313 n.468_470delGATinsCAAG non_coding_transcript_exon_variant 0.5 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.53 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.54 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.49 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.21 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.21 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.2 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.6 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.22 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.18 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.81 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.85 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.23 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.22 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.27 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472583 n.738T>C non_coding_transcript_exon_variant 0.27 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.29 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.23 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.22 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.18 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.65 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>A non_coding_transcript_exon_variant 0.62 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.63 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.64 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 0.62 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.64 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472953 n.1108G>A non_coding_transcript_exon_variant 0.46 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.64 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.68 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.71 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.18 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.28 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.25 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.25 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.28 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.4 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.59 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473121 n.1276_1277delTTinsCA non_coding_transcript_exon_variant 0.36 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.38 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.43 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.28 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.77 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.21 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445_1446delCGinsTGT non_coding_transcript_exon_variant 0.73 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.79 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.29 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.29 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473812 n.155G>A non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid
rrl 1473814 n.157A>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1473815 n.158T>A non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1473830 n.173T>A non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.41 capreomycin
linezolid Uncertain significance
rrl 1473845 n.188G>C non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid
rrl 1474091 n.434C>T non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid
rrl 1474096 n.439C>T non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1474102 n.445_446insTGAAC non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1474106 n.449_453delATCAAinsG non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1474287 n.630_646delTCCTTTTCCTCTCCGGAinsCTCCACTTTGT non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1474305 n.648G>C non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1474308 n.653_654delTG non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474381 n.724T>A non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1474421 n.764_782delGCGCATACGCGCGTGTGAAinsAATAGTGTGTGGTG non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474483 n.826C>G non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474540 n.883T>C non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1474551 n.894G>C non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474558 n.901G>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474624 n.967G>C non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1474660 n.1003G>A non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474690 n.1033C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060_1061insGTGAG non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1474725 n.1068C>G non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.35 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.35 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474801 n.1144G>A non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1475353 n.1696A>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid
rrl 1475354 n.1697A>G non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid
rrl 1475396 n.1739C>G non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1475397 n.1740G>T non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.2 capreomycin
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>C non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1475615 n.1958C>G non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 0.18 capreomycin
linezolid
rrl 1475618 n.1961C>T non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1475626 n.1969delTinsCC non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1475629 n.1972G>C non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475655 n.1998T>G non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475752 n.2095_2098delCCGTinsGGG non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1475752 n.2096C>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1475752 n.2095_2098delCCGTinsGGG non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1475752 n.2096C>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1475757 n.2100A>C non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1475759 n.2102C>G non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475776 n.2119G>C non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.68 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.19 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.79 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.2 capreomycin
linezolid
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.48 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.46 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.26 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.63 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.65 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.23 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
inhA 1673784 c.-418G>A upstream_gene_variant 0.73 ethionamide
isoniazid
inhA 1673787 c.-415G>A upstream_gene_variant 0.73 ethionamide
isoniazid Uncertain significance
rpsA 1833676 c.135A>G synonymous_variant 0.33 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.33 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.32 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.33 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.33 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 0.41 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 0.43 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.39 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 0.39 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.39 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.39 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.44 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.56 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 0.58 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.58 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.58 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.67 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.57 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.6 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.57 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.57 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.47 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.47 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.41 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.44 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.41 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.44 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.57 pyrazinamide
rpsA 1833955 c.414G>C synonymous_variant 0.25 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.58 pyrazinamide
rpsA 1833973 c.432G>C synonymous_variant 0.23 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.42 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.65 pyrazinamide
rpsA 1833985 c.444G>C synonymous_variant 0.23 pyrazinamide
rpsA 1833988 c.447C>G synonymous_variant 0.23 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 0.39 pyrazinamide
rpsA 1833994 c.453G>C synonymous_variant 0.22 pyrazinamide
rpsA 1833997 c.456G>C synonymous_variant 0.2 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.3 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.56 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.61 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.61 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.32 pyrazinamide
rpsA 1834024 c.483G>C synonymous_variant 0.32 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.59 pyrazinamide
rpsA 1834034 p.Ile165Val missense_variant 0.3 pyrazinamide
rpsA 1834054 c.513C>G synonymous_variant 0.3 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.23 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.47 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 0.5 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.45 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.43 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.43 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.52 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.5 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
rpsA 1834451 c.910T>C synonymous_variant 0.69 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.65 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.75 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.64 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.67 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.67 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.48 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.45 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.5 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.56 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.5 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.5 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.58 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.69 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.45 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.45 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.53 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.5 linezolid
tsnR 1853375 c.-231G>T upstream_gene_variant 0.5 linezolid
tsnR 1853384 c.-222G>T upstream_gene_variant 0.53 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.53 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.53 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.53 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 0.69 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.69 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.67 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.67 linezolid
Rv2752c 3065109 c.1081_1083delAGAinsCC frameshift_variant&missense_variant 0.55 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065115 c.1077C>T synonymous_variant 0.55 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065126 p.Ser356Ala missense_variant 0.43 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065133 c.1059T>C synonymous_variant 0.5 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065142 c.1050A>C synonymous_variant 0.5 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.5 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
rpoA 3877764 c.744C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>A synonymous_variant 0.38 rifampicin
rpoA 3877803 c.705G>C synonymous_variant 0.38 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.69 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.67 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.65 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.65 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.67 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.67 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoA 3878310 c.198G>C synonymous_variant 0.6 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
clpC1 4038623 c.2082A>G synonymous_variant 0.44 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.48 pyrazinamide
clpC1 4038647 c.2058T>C synonymous_variant 0.42 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.48 pyrazinamide
clpC1 4038660 c.2044_2045delTCinsAG synonymous_variant 0.38 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.48 pyrazinamide
clpC1 4038671 c.2034T>A synonymous_variant 0.41 pyrazinamide
clpC1 4038679 p.Pro676Ala missense_variant 0.5 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.37 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.46 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.46 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.48 pyrazinamide
clpC1 4038725 c.1980C>G synonymous_variant 0.43 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.41 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.41 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 0.41 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.37 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.38 pyrazinamide
clpC1 4038776 c.1929G>A synonymous_variant 0.38 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.39 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.39 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.47 pyrazinamide
clpC1 4038815 c.1890G>T synonymous_variant 0.48 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.43 pyrazinamide
clpC1 4038857 c.1848C>G synonymous_variant 0.48 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 0.52 pyrazinamide
clpC1 4038905 c.1800A>C synonymous_variant 0.55 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.55 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.55 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.55 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.5 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.83 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.82 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.69 pyrazinamide
clpC1 4039091 c.1614G>T synonymous_variant 0.69 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 0.6 pyrazinamide
clpC1 4039106 c.1599G>T synonymous_variant 0.6 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.54 pyrazinamide
clpC1 4039118 c.1587C>G synonymous_variant 0.57 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.57 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.62 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.67 pyrazinamide
clpC1 4039166 c.1539G>A synonymous_variant 0.69 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.69 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.69 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.86 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 0.85 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.83 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.71 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4039241 c.1464G>C synonymous_variant 0.75 pyrazinamide
clpC1 4039265 c.1440C>T synonymous_variant 0.64 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
clpC1 4039280 c.1425G>T synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.42 pyrazinamide
clpC1 4039289 c.1416T>C synonymous_variant 0.45 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.42 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 0.42 pyrazinamide
clpC1 4039313 c.1392C>T synonymous_variant 0.42 pyrazinamide
clpC1 4039320 p.Ala462Gly missense_variant 0.38 pyrazinamide
clpC1 4039328 c.1377A>T synonymous_variant 0.44 pyrazinamide
clpC1 4039337 c.1368A>C synonymous_variant 0.48 pyrazinamide
clpC1 4039349 c.1356C>T synonymous_variant 0.41 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 0.56 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.5 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.53 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.54 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.56 pyrazinamide
clpC1 4039889 c.816G>C synonymous_variant 0.56 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.67 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.76 pyrazinamide
clpC1 4039934 c.771G>A synonymous_variant 0.71 pyrazinamide
clpC1 4039946 c.759A>G synonymous_variant 0.67 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.57 pyrazinamide
embB 4248070 c.1557T>C synonymous_variant 0.5 ethambutol
embB 4248079 c.1566C>T synonymous_variant 0.47 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.54 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.5 ethambutol
embB 4249408 c.2895G>A synonymous_variant 1.0 ethambutol Not assoc w R