TB-Profiler result

Run: SRR10808668
Summary

Run ID: SRR10808668

Sample name:

Date: 2025-09-15T15:30:30.405260

Number of reads: 1840427

Percentage reads mapped: 65.7

Median coverage: 59.0

Strain: lineage2.2.1

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage2 East-Asian RD105 100.0
lineage2.2 East-Asian (Beijing) RD105;RD207 100.0
lineage2.2.1 East-Asian (Beijing) RD105;RD207;RD181 100.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 5150 c.-90G>A upstream_gene_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6181 c.942C>T synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7153 c.-149G>T upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7165 c.-137C>T upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7178 c.-124T>C upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 7198 c.1959C>T synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7706 c.405C>G synonymous_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7710 c.409T>C synonymous_variant 0.24 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7715 c.414G>C synonymous_variant 0.28 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7728 c.427A>C synonymous_variant 0.35 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7745 c.444G>A synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7754 p.Asp151Glu missense_variant 0.29 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7763 c.462T>C synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 0.32 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7787 c.486G>A synonymous_variant 0.32 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7790 c.489G>C synonymous_variant 0.31 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7793 c.492G>C synonymous_variant 0.31 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7799 c.498A>G synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 0.25 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7835 c.534A>G synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 0.23 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7853 c.552C>T synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7865 c.564T>C synonymous_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8246 c.945C>G synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8247 p.Ile316Val missense_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8253 p.Ile318Leu missense_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8267 c.966G>C synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8273 c.972C>G synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8324 c.1023T>C synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8442 c.1141C>T synonymous_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8453 c.1152A>G synonymous_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8462 c.1161A>G synonymous_variant 0.19 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8471 c.1170T>C synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8480 c.1179C>A synonymous_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8486 c.1185T>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8492 c.1191G>C synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8501 c.1200G>C synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8873 c.1572A>G synonymous_variant 0.16 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8900 c.1599G>C synonymous_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8903 c.1602T>C synonymous_variant 0.17 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>A synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8942 c.1641G>C synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.15 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Thr missense_variant 0.14 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8987 c.1686C>G synonymous_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9314 c.2013G>C synonymous_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
fgd1 491490 c.708C>T synonymous_variant 0.15 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491499 c.717G>C synonymous_variant 0.15 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491508 c.726A>G synonymous_variant 0.15 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491509 c.727T>C synonymous_variant 0.15 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491512 p.Asn244Glu missense_variant 0.15 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491526 c.744T>C synonymous_variant 0.16 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491542 c.760T>C synonymous_variant 0.16 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491548 p.Ala256Pro missense_variant 0.16 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491563 c.781_783delAGCinsTCG synonymous_variant 0.2 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491574 c.792C>T synonymous_variant 0.21 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491601 c.819T>C synonymous_variant 0.22 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491610 c.828A>C synonymous_variant 0.21 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491616 c.834A>G synonymous_variant 0.21 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491620 p.Ile280Val missense_variant 0.19 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491742 c.960T>C synonymous_variant 1.0 clofazimine Not assoc w R
delamanid Not assoc w R - Interim
pretomanid Uncertain significance
mshA 575756 c.409C>T synonymous_variant 0.15 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575772 p.Val142Ala missense_variant 0.15 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575779 c.432A>G synonymous_variant 0.15 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575907 p.Ala187Val missense_variant 0.98 ethionamide Not assoc w R
isoniazid Not assoc w R
ccsA 620625 p.Ile245Met missense_variant 1.0 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Uncertain significance
ccsA 620724 c.834C>T synonymous_variant 0.17 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
Rv0565c 657081 c.390G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 657142 p.Arg110His missense_variant 1.0 ethionamide Uncertain significance
nusG 734499 c.246G>C synonymous_variant 0.17 rifampicin Uncertain significance
nusG 734532 c.279A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 760130 p.Asp108Glu missense_variant 0.16 rifampicin Uncertain significance
rpoB 760139 c.333A>T synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 760142 c.336C>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 760184 c.378A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 760256 c.450C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoB 760316 c.510C>G synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 760317 c.511_512delAGinsTC synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 760325 c.519G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 760331 c.525G>T synonymous_variant 0.26 rifampicin Uncertain significance
rpoB 760334 c.528G>T synonymous_variant 0.26 rifampicin Uncertain significance
rpoB 760340 c.534G>C synonymous_variant 0.26 rifampicin Uncertain significance
rpoB 760355 p.Glu183Asp missense_variant 0.26 rifampicin Uncertain significance
rpoB 760357 p.Thr184Ser missense_variant 0.26 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.25 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 0.23 rifampicin Uncertain significance
rpoB 760407 p.Ser201Gly missense_variant 0.22 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 760451 c.645C>A synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 760457 c.651C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 760499 c.693G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 760502 c.696C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760508 c.702G>A synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.17 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760535 c.729C>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 760721 c.915C>G synonymous_variant 0.25 rifampicin Uncertain significance
rpoB 760724 c.918T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.25 rifampicin Uncertain significance
rpoB 760751 c.945G>C synonymous_variant 0.25 rifampicin Uncertain significance
rpoB 760755 p.His317Asn missense_variant 0.21 rifampicin Uncertain significance
rpoB 760759 p.Val318Ala missense_variant 0.21 rifampicin Uncertain significance
rpoB 760764 p.Glu320Gln missense_variant 0.23 rifampicin Uncertain significance
rpoB 760769 c.963C>G synonymous_variant 0.24 rifampicin Uncertain significance
rpoB 760784 c.978G>C synonymous_variant 0.27 rifampicin Uncertain significance
rpoB 760787 c.981G>C synonymous_variant 0.26 rifampicin Uncertain significance
rpoB 760793 c.987A>G synonymous_variant 0.29 rifampicin Uncertain significance
rpoB 760805 c.999G>C synonymous_variant 0.29 rifampicin Uncertain significance
rpoB 760808 c.1002C>G synonymous_variant 0.27 rifampicin Uncertain significance
rpoB 760817 c.1011A>G synonymous_variant 0.26 rifampicin Uncertain significance
rpoB 760820 c.1014T>C synonymous_variant 0.26 rifampicin Uncertain significance
rpoB 760826 c.1020C>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760829 c.1023C>T synonymous_variant 0.28 rifampicin Uncertain significance
rpoB 760830 c.1024T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoB 760862 c.1056G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoB 760883 c.1077G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 760886 c.1080A>G synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 760887 p.Thr361Val missense_variant 0.19 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.25 rifampicin Uncertain significance
rpoB 761102 c.1296A>G synonymous_variant 0.25 rifampicin Uncertain significance
rpoB 761132 c.1326G>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 761217 p.Pro471Ser missense_variant 0.23 rifampicin Uncertain significance
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.24 rifampicin Uncertain significance
rpoB 761234 c.1428G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoB 761354 c.1548C>T synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 761360 c.1554T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 761361 c.1555_1556delAGinsTC synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 761367 p.Glu521Gln missense_variant 0.21 rifampicin Uncertain significance
rpoB 761374 p.Val523Asp missense_variant 0.2 rifampicin Uncertain significance
rpoB 761408 c.1602G>T synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 761414 c.1608A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 761435 c.1629T>C synonymous_variant 0.13 rifampicin Uncertain significance
rpoB 761570 c.1764T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 761606 c.1800C>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 761612 c.1806G>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 761666 c.1860G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 761669 c.1863C>T synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 761675 c.1869G>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 761948 c.2142G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 761972 c.2166C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.27 rifampicin Uncertain significance
rpoB 762002 c.2196C>G synonymous_variant 0.28 rifampicin Uncertain significance
rpoB 762038 c.2232C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.23 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.26 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.24 rifampicin Uncertain significance
rpoB 762137 c.2331C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.22 rifampicin Uncertain significance
rpoB 762143 c.2337T>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoB 762149 c.2343G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>T synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 762293 c.2487T>G synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 762308 c.2502G>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoB 762314 c.2508C>T synonymous_variant 0.2 rifampicin Uncertain significance
rpoB 762317 c.2511A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 762341 c.2535G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 762347 c.2541T>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 762350 c.2544C>G synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 762353 c.2547C>T synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 762359 c.2553C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 762362 p.Glu852Asp missense_variant 0.17 rifampicin Uncertain significance
rpoB 762369 c.2563T>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 762374 c.-996G>C upstream_gene_variant 0.16 rifampicin Uncertain significance
rpoC 762395 c.-975G>C upstream_gene_variant 0.14 rifampicin Uncertain significance
rpoB 762926 c.3120C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 762989 c.3183G>A synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 763049 c.-321G>A upstream_gene_variant 0.34 rifampicin Uncertain significance
rpoB 763053 c.3247T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 763058 c.-312C>G upstream_gene_variant 0.35 rifampicin Uncertain significance
rpoB 763070 c.3264T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 763082 c.3276C>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 763109 c.-261C>G upstream_gene_variant 0.29 rifampicin Uncertain significance
rpoB 763115 c.3309T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.27 rifampicin Uncertain significance
rpoB 763136 c.3330C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 0.27 rifampicin Uncertain significance
rpoC 763158 c.-212C>T upstream_gene_variant 0.3 rifampicin Uncertain significance
rpoB 763166 c.3360A>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.3 rifampicin Uncertain significance
rpoC 763193 c.-177C>T upstream_gene_variant 0.29 rifampicin Uncertain significance
rpoC 763202 c.-168A>C upstream_gene_variant 0.21 rifampicin Uncertain significance
rpoC 763205 c.-165G>C upstream_gene_variant 0.21 rifampicin Uncertain significance
rpoC 763208 c.-162T>C upstream_gene_variant 0.21 rifampicin Uncertain significance
rpoB 763214 c.3408T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.2 rifampicin Uncertain significance
rpoB 763227 p.Leu1141Met missense_variant 0.17 rifampicin Uncertain significance
rpoC 763232 c.-138C>T upstream_gene_variant 0.17 rifampicin Uncertain significance
rpoB 763235 p.Glu1143Asp missense_variant 0.17 rifampicin Uncertain significance
rpoB 763241 p.Glu1145Asp missense_variant 0.17 rifampicin Uncertain significance
rpoC 763468 c.99G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 763492 c.123G>T synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 763528 c.159G>A synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>T synonymous_variant 0.36 rifampicin Uncertain significance
rpoC 763573 c.204G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 0.42 rifampicin Uncertain significance
rpoC 763660 c.291T>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>T synonymous_variant 0.41 rifampicin Uncertain significance
rpoC 763702 c.333C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 0.39 rifampicin Uncertain significance
rpoC 763714 c.345G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.36 rifampicin Uncertain significance
rpoC 763741 c.372C>T synonymous_variant 0.28 rifampicin Uncertain significance
rpoC 763747 c.378G>A synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 763765 c.396T>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763792 p.Glu141Asp missense_variant 0.3 rifampicin Uncertain significance
rpoC 763807 c.438T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 763811 p.Leu148Val missense_variant 0.27 rifampicin Uncertain significance
rpoC 763831 c.462A>G synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 763837 c.468G>C synonymous_variant 0.25 rifampicin Uncertain significance
rpoC 763840 c.471G>C synonymous_variant 0.28 rifampicin Uncertain significance
rpoC 763858 c.489A>G synonymous_variant 0.25 rifampicin Uncertain significance
rpoC 763867 c.498C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763871 p.Gly168Ser missense_variant 0.26 rifampicin Uncertain significance
rpoC 763876 p.Glu169Asp missense_variant 0.25 rifampicin Uncertain significance
rpoC 763879 c.510A>G synonymous_variant 0.25 rifampicin Uncertain significance
rpoC 763888 c.519G>C synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 763891 c.522G>C synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 763894 c.525A>G synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 763900 c.531G>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 763933 c.564C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 0.26 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.25 rifampicin Uncertain significance
rpoC 763947 p.Ala193Val missense_variant 0.23 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 0.25 rifampicin Uncertain significance
rpoC 763987 c.618C>T synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 764153 p.Gln262Lys missense_variant 0.13 rifampicin Uncertain significance
rpoC 764182 p.Asp271Glu missense_variant 0.15 rifampicin Uncertain significance
rpoC 764213 c.844C>A synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 764254 c.885G>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 764263 c.894G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 764266 c.897T>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 764272 c.903G>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 764278 c.909A>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764287 c.918C>T synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 764293 c.924G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764297 p.Met310Leu missense_variant 0.18 rifampicin Uncertain significance
rpoC 764311 c.942C>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 764341 c.972G>T synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 764344 c.975C>T synonymous_variant 0.28 rifampicin Uncertain significance
rpoC 764353 c.984G>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>T synonymous_variant 0.34 rifampicin Uncertain significance
rpoC 764380 c.1011G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 764446 c.1077T>C synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 764449 c.1080G>C synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 764455 c.1086G>C synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 764458 c.1089G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.23 rifampicin Uncertain significance
rpoC 764491 c.1122G>T synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 764497 c.1128A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.22 rifampicin Uncertain significance
rpoC 764521 c.1152T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764671 c.1302G>C synonymous_variant 0.31 rifampicin Uncertain significance
rpoC 764692 c.1323C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.35 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 0.28 rifampicin Uncertain significance
rpoC 764878 c.1509C>T synonymous_variant 0.25 rifampicin Uncertain significance
rpoC 764887 c.1518G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.27 rifampicin Uncertain significance
rpoC 764912 p.Met515Gln missense_variant 0.26 rifampicin Uncertain significance
rpoC 764935 c.1566T>C synonymous_variant 0.22 rifampicin Uncertain significance
rpoC 764948 c.1579T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 765376 c.2007C>T synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 765379 c.2010G>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 765383 p.Met672Leu missense_variant 0.18 rifampicin Uncertain significance
rpoC 765404 p.Leu679Lys missense_variant 0.24 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 765412 c.2043T>C synonymous_variant 0.22 rifampicin Uncertain significance
rpoC 765425 p.Lys686Glu missense_variant 0.24 rifampicin Uncertain significance
rpoC 765445 c.2076G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Arg missense_variant 0.26 rifampicin Uncertain significance
rpoC 765466 c.2097C>T synonymous_variant 0.29 rifampicin Uncertain significance
rpoC 765478 c.2109T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 0.27 rifampicin Uncertain significance
rpoC 765496 c.2127C>G synonymous_variant 0.22 rifampicin Uncertain significance
rpoC 765499 c.2130C>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 765817 c.2448G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 765823 c.2454C>A synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 0.26 rifampicin Uncertain significance
rpoC 765875 p.Val836Ile missense_variant 0.26 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.28 rifampicin Uncertain significance
rpoC 765904 c.2535C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 0.3 rifampicin Uncertain significance
rpoC 765934 c.2565C>T synonymous_variant 0.31 rifampicin Uncertain significance
rpoC 765940 c.2571A>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 766456 c.3087C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 766459 c.3090G>T synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 766483 c.3114G>T synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 766484 p.Val1039Ile missense_variant 0.2 rifampicin Uncertain significance
rpoC 766492 c.3123T>G synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 766493 p.Gly1042Asn missense_variant 0.2 rifampicin Uncertain significance
rpoC 766504 c.3135G>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 766517 p.Thr1050Ala missense_variant 0.16 rifampicin Uncertain significance
rpoC 766528 c.3159T>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 766534 c.3165C>G synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 766702 c.3333G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 766714 c.3345G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 766717 c.3348C>G synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 766720 c.3351C>T synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 766726 c.3357T>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 766732 c.3363G>T synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 766738 c.3369G>T synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 766741 c.3372G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 766765 c.3396A>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 766774 c.3405T>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 766775 p.Arg1136Lys missense_variant 0.17 rifampicin Uncertain significance
rpoC 766780 c.3411G>A synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 766798 c.3429C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 766807 c.3438T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 766876 c.3507C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 766882 c.3513C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 766883 p.Ser1172Ala missense_variant 0.16 rifampicin Uncertain significance
rpoC 766895 c.3526T>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 766900 c.3531T>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 766909 c.3540G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 766911 p.Ile1181Thr missense_variant 0.16 rifampicin Uncertain significance
rpoC 766915 p.Asp1182Glu missense_variant 0.17 rifampicin Uncertain significance
rpoC 766921 c.3552G>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 766931 p.Ala1188Thr missense_variant 0.2 rifampicin Uncertain significance
rpoC 766942 c.3573C>T synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>C synonymous_variant 0.23 rifampicin Uncertain significance
rpoC 766963 c.3594T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 767068 c.3699G>C synonymous_variant 0.3 rifampicin Uncertain significance
rpoC 767098 c.3729T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 767105 p.Asn1246Gln missense_variant 0.25 rifampicin Uncertain significance
rpoC 767158 c.3789T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 775817 c.2664T>C synonymous_variant 0.18 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
mmpL5 775856 c.2625T>C synonymous_variant 0.2 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 775904 c.2577G>A synonymous_variant 0.19 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 775915 p.Ala856Ser missense_variant 0.16 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 775916 c.2565T>C synonymous_variant 0.15 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 775937 c.2544G>T synonymous_variant 0.15 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 776100 p.Thr794Ile missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 776182 p.Asp767Asn missense_variant 1.0 bedaquiline Not assoc w R
clofazimine Not assoc w R
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0 bedaquiline Uncertain significance
clofazimine Uncertain significance
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781751 c.192G>C synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781754 c.195G>T synonymous_variant 0.16 streptomycin Uncertain significance
rpsL 781760 c.201T>C synonymous_variant 0.18 streptomycin Uncertain significance
rpsL 781766 c.207C>T synonymous_variant 0.21 streptomycin Not assoc w R - Interim
rpsL 781811 c.252C>T synonymous_variant 0.23 streptomycin Uncertain significance
rpsL 781814 c.255C>T synonymous_variant 0.23 streptomycin Uncertain significance
rpsL 781817 c.258G>T synonymous_variant 0.24 streptomycin Uncertain significance
rpsL 781829 c.270G>C synonymous_variant 0.24 streptomycin Uncertain significance
rpsL 781832 c.273T>C synonymous_variant 0.23 streptomycin Uncertain significance
rpsL 781838 c.279G>C synonymous_variant 0.23 streptomycin Uncertain significance
rpsL 781841 c.282C>T synonymous_variant 0.22 streptomycin Uncertain significance
rpsL 781853 c.294C>T synonymous_variant 0.24 streptomycin Uncertain significance
rpsL 781859 c.300T>A synonymous_variant 0.26 streptomycin Uncertain significance
rpsL 781865 c.306G>C synonymous_variant 0.25 streptomycin Uncertain significance
rpsL 781868 c.309T>C synonymous_variant 0.25 streptomycin Uncertain significance
rpsL 781871 c.312G>C synonymous_variant 0.25 streptomycin Uncertain significance
rpsL 781892 c.333A>G synonymous_variant 0.31 streptomycin Uncertain significance
rpsL 781898 c.339A>C synonymous_variant 0.3 streptomycin Uncertain significance
rpsL 781901 c.342C>T synonymous_variant 0.27 streptomycin Uncertain significance
rpsL 781907 c.348T>C synonymous_variant 0.26 streptomycin Uncertain significance
rpsL 781916 c.357T>C synonymous_variant 0.26 streptomycin Uncertain significance
rpsL 781929 p.Gly124Ser missense_variant 0.2 streptomycin Uncertain significance
rplC 800633 c.-176T>C upstream_gene_variant 0.17 linezolid Uncertain significance
rplC 800642 c.-167C>T upstream_gene_variant 0.18 linezolid Uncertain significance
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 isoniazid Not assoc w R
levofloxacin Not assoc w R
moxifloxacin Not assoc w R
rifampicin Not assoc w R
fbiC 1304490 c.1560C>G synonymous_variant 0.18 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304499 c.1569T>G synonymous_variant 0.2 clofazimine Not assoc w R - Interim
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304515 p.Ala529Thr missense_variant 0.2 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304526 c.1596T>G synonymous_variant 0.24 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304553 c.1623C>A synonymous_variant 0.22 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304556 c.1626C>T synonymous_variant 0.22 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304559 p.Glu543Asp missense_variant 0.22 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304562 c.1632G>C synonymous_variant 0.23 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304565 c.1635C>G synonymous_variant 0.23 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304568 c.1638T>C synonymous_variant 0.23 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304571 c.1641G>C synonymous_variant 0.23 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304580 c.1650T>C synonymous_variant 0.23 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304613 c.1683T>C synonymous_variant 0.18 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304634 c.1704C>G synonymous_variant 0.16 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304637 c.1707G>A synonymous_variant 0.15 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304640 c.1710A>C synonymous_variant 0.16 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304646 c.1716T>C synonymous_variant 0.14 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304658 c.1728C>G synonymous_variant 0.14 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
sigE 1364839 c.427T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
sigE 1364859 c.447C>T synonymous_variant 0.16 pyrazinamide Uncertain significance
sigE 1364865 c.453G>T synonymous_variant 0.15 pyrazinamide Uncertain significance
sigE 1364867 p.Ala152Gly missense_variant 0.15 pyrazinamide Uncertain significance
sigE 1364950 p.Ala180Ser missense_variant 0.14 pyrazinamide Uncertain significance
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0 isoniazid Uncertain significance
pyrazinamide Uncertain significance
streptomycin Uncertain significance
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.29 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.25 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.25 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472028 n.183A>G non_coding_transcript_exon_variant 0.25 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.24 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472032 n.187G>T non_coding_transcript_exon_variant 0.24 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.24 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.24 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.23 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472041 n.196C>G non_coding_transcript_exon_variant 0.24 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.26 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.35 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.36 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.45 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.46 amikacin Not assoc w R
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.45 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.48 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.25 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.22 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.39 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.44 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.45 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.45 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.27 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472848 n.1003T>A non_coding_transcript_exon_variant 0.27 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.28 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.31 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 0.33 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.32 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.45 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.4 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.42 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 0.4 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.43 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.41 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.43 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.41 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473811 n.154C>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473833 n.176G>A non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474091 n.434C>T non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474096 n.439C>T non_coding_transcript_exon_variant 0.18 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474101 n.446_450delAGTAT non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474108 n.451C>T non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474110 n.454_455insGGTGT non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474287 n.630_635delTCCTTTinsCTCGACTTG non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474294 n.638_649delCTCTCCGGAGGA non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053T>A non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474711 n.1054G>C non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474712 n.1055G>A non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474713 n.1056T>A non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474716 n.1059_1063delAAAGCinsCCAAGAAT non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475061 n.1404C>A non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475353 n.1696A>T non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475354 n.1697A>G non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475378 n.1721A>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475379 n.1722G>C non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475387 n.1730C>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475397 n.1740G>T non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475398 n.1741C>G non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475399 n.1742T>G non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475603 n.1946G>C non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475615 n.1958C>G non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475618 n.1961C>T non_coding_transcript_exon_variant 0.19 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475626 n.1969delTinsCC non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475629 n.1972G>C non_coding_transcript_exon_variant 0.2 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.41 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476031 n.2374_2378delCCTCGinsTTCAC non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>A non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.58 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.58 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.54 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.49 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.17 capreomycin Uncertain significance
linezolid Uncertain significance
inhA 1673547 c.-655T>C upstream_gene_variant 0.2 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673556 c.-646C>G upstream_gene_variant 0.21 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673580 c.-622T>C upstream_gene_variant 0.24 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673595 c.-607A>C upstream_gene_variant 0.19 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673596 c.-606_-604delAAGinsGAC upstream_gene_variant 0.19 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673607 c.-595T>C upstream_gene_variant 0.22 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673615 c.-587_-586delAAinsTG upstream_gene_variant 0.23 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673619 c.-583T>C upstream_gene_variant 0.23 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673633 c.-569G>A upstream_gene_variant 0.24 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673637 c.-565C>G upstream_gene_variant 0.21 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673646 c.-556T>C upstream_gene_variant 0.21 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673652 c.-550C>G upstream_gene_variant 0.18 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673657 c.-545_-544delCGinsAA upstream_gene_variant 0.17 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673660 c.-542C>A upstream_gene_variant 0.2 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673664 c.-538A>C upstream_gene_variant 0.22 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673691 c.-511G>T upstream_gene_variant 0.25 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673709 c.-493C>T upstream_gene_variant 0.19 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673710 c.-492_-490delCTAinsATC upstream_gene_variant 0.2 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673716 c.-486_-485delGCinsCA upstream_gene_variant 0.2 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673721 c.-481C>T upstream_gene_variant 0.2 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673724 c.-478A>G upstream_gene_variant 0.2 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673730 c.-472C>G upstream_gene_variant 0.19 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673749 c.-453_-452delAAinsCG upstream_gene_variant 0.2 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673760 c.-442G>C upstream_gene_variant 0.18 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673772 c.-430C>G upstream_gene_variant 0.19 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673799 c.-403T>G upstream_gene_variant 0.15 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673802 c.-400A>G upstream_gene_variant 0.15 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674489 c.288G>T synonymous_variant 0.15 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674507 c.306G>C synonymous_variant 0.16 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674514 p.Ile105Val missense_variant 0.16 ethionamide Uncertain significance
isoniazid Uncertain significance
rpsA 1833634 c.93G>A synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1833661 c.120A>G synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1833664 c.123C>A synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1833676 c.135A>G synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1833679 c.138G>T synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1833685 c.144G>T synonymous_variant 0.28 pyrazinamide Uncertain significance
rpsA 1833694 c.153G>C synonymous_variant 0.3 pyrazinamide Uncertain significance
rpsA 1833697 c.156C>G synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1833709 c.168C>T synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1833724 c.183C>T synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1833727 c.186G>C synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1833730 c.189C>T synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1833733 c.192C>T synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1833734 p.Ala65Ser missense_variant 0.29 pyrazinamide Uncertain significance
rpsA 1833745 c.204G>C synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1833748 c.207C>G synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1833787 c.246C>G synonymous_variant 0.32 pyrazinamide Uncertain significance
rpsA 1833790 c.249T>C synonymous_variant 0.31 pyrazinamide Uncertain significance
rpsA 1833793 c.252C>T synonymous_variant 0.31 pyrazinamide Uncertain significance
rpsA 1833802 c.261A>G synonymous_variant 0.33 pyrazinamide Uncertain significance
rpsA 1833808 c.267G>C synonymous_variant 0.32 pyrazinamide Uncertain significance
rpsA 1833811 c.270G>T synonymous_variant 0.32 pyrazinamide Uncertain significance
rpsA 1833829 c.288A>G synonymous_variant 0.31 pyrazinamide Uncertain significance
rpsA 1833832 c.291G>A synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1833838 c.297G>C synonymous_variant 0.3 pyrazinamide Uncertain significance
rpsA 1833841 c.300C>G synonymous_variant 0.3 pyrazinamide Uncertain significance
rpsA 1833847 c.306C>G synonymous_variant 0.32 pyrazinamide Uncertain significance
rpsA 1833856 c.315A>G synonymous_variant 0.3 pyrazinamide Uncertain significance
rpsA 1833859 c.318C>T synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1833862 c.321G>T synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1833877 c.336C>T synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1833894 p.Ala118Glu missense_variant 0.31 pyrazinamide Uncertain significance
rpsA 1833928 c.387G>C synonymous_variant 0.29 pyrazinamide Uncertain significance
rpsA 1833949 c.408T>C synonymous_variant 0.3 pyrazinamide Uncertain significance
rpsA 1833970 c.429G>T synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1833979 c.438T>C synonymous_variant 0.28 pyrazinamide Uncertain significance
rpsA 1833991 c.450C>A synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1834000 c.459G>C synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1834009 c.468C>T synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834012 c.471G>T synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834015 c.474G>C synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834021 c.480C>T synonymous_variant 0.28 pyrazinamide Uncertain significance
rpsA 1834030 c.489C>G synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834162 c.621A>G synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1834169 p.Thr210Ala missense_variant 0.16 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1834190 c.649_650delTCinsAG synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1834213 c.672G>C synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834228 c.687C>T synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1834231 c.690T>C synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834234 c.693G>C synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834240 c.699T>C synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834249 c.708T>C synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1834261 c.720A>G synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834279 c.738C>T synonymous_variant 0.22 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834303 c.762T>G synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834306 c.765T>C synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834345 c.804C>T synonymous_variant 0.25 pyrazinamide Uncertain significance
rpsA 1834348 c.807T>C synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834366 c.825A>G synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
rpsA 1834378 c.837T>C synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>T synonymous_variant 0.3 pyrazinamide Uncertain significance
rpsA 1834411 c.870T>C synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1834423 c.882G>T synonymous_variant 0.27 pyrazinamide Uncertain significance
rpsA 1834451 c.910T>C synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834456 c.915T>G synonymous_variant 0.26 pyrazinamide Uncertain significance
rpsA 1834465 c.924T>C synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834468 c.927A>G synonymous_variant 0.23 pyrazinamide Uncertain significance
rpsA 1834489 c.948T>C synonymous_variant 0.24 pyrazinamide Uncertain significance
rpsA 1834513 c.972C>G synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834520 p.Ala327Ser missense_variant 0.23 pyrazinamide Uncertain significance
rpsA 1834528 c.987T>C synonymous_variant 0.22 pyrazinamide Uncertain significance
rpsA 1834540 c.999G>C synonymous_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834543 c.1002C>G synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1834546 c.1005T>C synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.21 pyrazinamide Uncertain significance
rpsA 1834732 c.1191T>C synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1834738 c.1197A>G synonymous_variant 0.2 pyrazinamide Uncertain significance
rpsA 1834753 c.1212T>C synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1834756 c.1215G>A synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1834759 c.1218A>C synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1834765 p.Glu408Asp missense_variant 0.17 pyrazinamide Uncertain significance
rpsA 1834774 c.1233C>G synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834776 p.Ala412Glu missense_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834780 c.1239A>G synonymous_variant 0.15 pyrazinamide Uncertain significance
tsnR 1853417 c.-189G>C upstream_gene_variant 0.15 linezolid Uncertain significance
tsnR 1853420 c.-186T>G upstream_gene_variant 0.16 linezolid Uncertain significance
tsnR 1853429 c.-177G>C upstream_gene_variant 0.2 linezolid Uncertain significance
tsnR 1853432 c.-174G>C upstream_gene_variant 0.21 linezolid Uncertain significance
tsnR 1853441 c.-165C>A upstream_gene_variant 0.22 linezolid Uncertain significance
tsnR 1853453 c.-153G>C upstream_gene_variant 0.2 linezolid Uncertain significance
tsnR 1853459 c.-147G>C upstream_gene_variant 0.18 linezolid Uncertain significance
tsnR 1853462 c.-144A>G upstream_gene_variant 0.18 linezolid Uncertain significance
tsnR 1853495 c.-111G>C upstream_gene_variant 0.16 linezolid Uncertain significance
tsnR 1853523 c.-83_-82delCGinsAA upstream_gene_variant 0.15 linezolid Uncertain significance
tsnR 1853531 c.-75A>C upstream_gene_variant 0.16 linezolid Uncertain significance
tsnR 1853537 c.-69C>T upstream_gene_variant 0.17 linezolid Uncertain significance
tsnR 1853540 c.-66A>G upstream_gene_variant 0.17 linezolid Uncertain significance
tsnR 1853552 c.-54C>G upstream_gene_variant 0.18 linezolid Uncertain significance
tsnR 1853561 c.-45G>A upstream_gene_variant 0.17 linezolid Uncertain significance
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Not assoc w R
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Not assoc w R
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
kasA 2517941 c.-174C>G upstream_gene_variant 0.16 isoniazid Uncertain significance
Rv2477c 2783584 p.Ala153Pro missense_variant 0.18 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783593 c.450T>C synonymous_variant 0.21 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783596 c.447C>T synonymous_variant 0.21 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783602 c.441G>C synonymous_variant 0.21 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783605 c.438T>C synonymous_variant 0.21 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
ribD 2987049 p.Phe71Val missense_variant 1.0 para-aminosalicylic_acid Uncertain significance
Rv2752c 3065058 c.1134C>G synonymous_variant 0.17 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3065061 c.1131C>T synonymous_variant 0.17 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3065064 c.1128G>C synonymous_variant 0.18 ethambutol Not assoc w R - Interim
isoniazid Not assoc w R - Interim
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Not assoc w R - Interim
Rv2752c 3065070 c.1122C>T synonymous_variant 0.18 ethambutol Not assoc w R - Interim
isoniazid Not assoc w R - Interim
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Not assoc w R - Interim
Rv2752c 3065085 c.1105_1107delAGGinsCGC synonymous_variant 0.16 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3065088 c.1104A>G synonymous_variant 0.16 ethambutol Not assoc w R - Interim
isoniazid Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
rifampicin Not assoc w R - Interim
Rv2752c 3065097 c.1095C>T synonymous_variant 0.17 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3065106 c.1086C>G synonymous_variant 0.17 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3065109 c.1081_1083delAGAinsCGG synonymous_variant 0.17 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3065126 p.Ser356Ala missense_variant 0.15 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3065130 c.1062A>G synonymous_variant 0.16 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3065133 c.1059T>C synonymous_variant 0.16 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.15 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine Uncertain significance
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0 pyrazinamide Not assoc w R - Interim
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
mtrB 3625222 c.1392T>C synonymous_variant 0.16 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
lpqB 3625240 c.-330T>C upstream_gene_variant 0.15 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625258 c.-348G>T upstream_gene_variant 0.15 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625267 c.1347T>C synonymous_variant 0.19 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 0.19 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625279 c.-369C>G upstream_gene_variant 0.19 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625285 c.-375G>C upstream_gene_variant 0.19 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625291 c.-381A>G upstream_gene_variant 0.19 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625312 c.-402G>A upstream_gene_variant 0.17 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625325 p.His430Arg missense_variant 0.16 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625345 c.-435T>C upstream_gene_variant 0.15 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625669 c.-759G>C upstream_gene_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625687 c.-777G>C upstream_gene_variant 0.24 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625690 c.-780T>C upstream_gene_variant 0.24 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625711 c.903C>T synonymous_variant 0.24 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625720 c.894G>C synonymous_variant 0.23 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.2 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
lpqB 3625735 c.-825C>T upstream_gene_variant 0.18 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625741 c.-831G>A upstream_gene_variant 0.18 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625747 c.867G>C synonymous_variant 0.16 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625753 p.Ala287Gln missense_variant 0.16 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625762 c.-852A>C upstream_gene_variant 0.16 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625765 c.849C>G synonymous_variant 0.16 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3626562 p.Pro18Ser missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
rpoA 3877593 c.915C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3877602 c.906C>T synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3877638 c.870T>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 0.18 rifampicin Uncertain significance
rpoA 3877656 c.852T>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.18 rifampicin Uncertain significance
rpoA 3877695 c.813C>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3877734 c.774G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoA 3877737 c.771G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3877743 c.765T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3877770 c.735_738delGTCAinsCAGC synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3877776 c.732T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>A synonymous_variant 0.19 rifampicin Uncertain significance
rpoA 3877803 c.705G>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoA 3877818 c.690A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoA 3877866 c.642G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoA 3877872 c.636C>T synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoA 3877887 c.621G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoA 3878118 c.390T>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoA 3878127 c.381G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3878130 c.378C>A synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3878143 p.Gly122Asp missense_variant 0.16 rifampicin Uncertain significance
rpoA 3878145 c.363C>G synonymous_variant 0.17 rifampicin Uncertain significance
rpoA 3878160 c.348C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878197 p.Glu104Ala missense_variant 0.25 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 0.26 rifampicin Uncertain significance
rpoA 3878256 c.252G>C synonymous_variant 0.29 rifampicin Uncertain significance
rpoA 3878262 p.Ser82Gly missense_variant 0.28 rifampicin Uncertain significance
rpoA 3878271 c.237T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.27 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoA 3878313 c.195G>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
clpC1 4038499 p.Ser736Gly missense_variant 0.17 pyrazinamide Uncertain significance
clpC1 4038519 p.Arg729Gln missense_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038534 p.Arg724His missense_variant 0.14 pyrazinamide Uncertain significance
clpC1 4038725 c.1980C>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4038740 c.1965G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4038812 c.1893T>C synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4038815 c.1890G>C synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4038860 c.1845G>C synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.18 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4038905 c.1800A>C synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4038908 c.1797C>G synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4038911 c.1794G>T synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4038914 c.1791G>C synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4038917 c.1788C>T synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4038923 c.1782A>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4038941 c.1764G>C synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039070 c.1635G>T synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039073 c.1632C>T synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039079 c.1626C>G synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039091 c.1614G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039097 c.1608G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039112 c.1593C>G synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039121 c.1584T>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039142 c.1563A>G synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039145 c.1560G>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039169 p.Glu512Asp missense_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039172 c.1533A>G synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039178 c.1527G>C synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039183 c.1522T>C synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039187 c.1518G>C synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039190 c.1515C>G synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039208 c.1497C>G synonymous_variant 0.25 pyrazinamide Uncertain significance
clpC1 4039226 c.1479T>C synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4039241 c.1464G>C synonymous_variant 0.26 pyrazinamide Uncertain significance
clpC1 4039265 c.1440C>T synonymous_variant 0.27 pyrazinamide Uncertain significance
clpC1 4039274 c.1431G>C synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
clpC1 4039280 c.1425G>T synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039295 c.1410A>C synonymous_variant 0.24 pyrazinamide Uncertain significance
clpC1 4039298 c.1407T>C synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039310 c.1395A>G synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039313 c.1392C>T synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039319 p.Ala462Gly missense_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039322 c.1383T>C synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039328 c.1377A>T synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039337 c.1368A>C synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039382 c.1323C>G synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039391 c.1314T>G synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039394 c.1311G>C synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039397 c.1308A>G synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039409 c.1296T>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039412 c.1293T>G synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039415 p.Glu430Asp missense_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039442 c.1263A>G synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039454 c.1251A>T synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4039463 c.1242C>G synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039466 c.1239T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039469 c.1236T>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039472 c.1233G>T synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039481 c.1224T>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039484 c.1221T>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039487 c.1218G>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039517 c.1188C>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4039541 c.1164C>G synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039556 c.1149G>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039559 c.1146C>G synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039570 p.Met379Leu missense_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039574 p.Ala377Gly missense_variant 0.19 pyrazinamide Uncertain significance
clpC1 4039577 c.1128T>C synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039592 c.1113G>C synonymous_variant 0.23 pyrazinamide Uncertain significance
clpC1 4039610 c.1095G>C synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039616 c.1089G>T synonymous_variant 0.21 pyrazinamide Uncertain significance
clpC1 4039622 c.1083C>T synonymous_variant 0.22 pyrazinamide Uncertain significance
clpC1 4039649 c.1056G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039670 c.1035G>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4039682 c.1023C>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039790 c.915C>G synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039925 c.780C>T synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4039991 c.714G>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4040015 c.690G>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4040021 c.684A>C synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.19 pyrazinamide Uncertain significance
clpC1 4040033 c.672G>C synonymous_variant 0.2 pyrazinamide Uncertain significance
clpC1 4040267 c.438A>G synonymous_variant 0.15 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4040303 c.402G>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040495 c.210C>A synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040522 c.183T>C synonymous_variant 0.16 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4040546 c.159G>C synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4040561 c.144A>G synonymous_variant 0.18 pyrazinamide Uncertain significance
clpC1 4040573 c.132T>A synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4040579 c.126A>G synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4040582 c.123G>C synonymous_variant 0.17 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.17 pyrazinamide Uncertain significance
clpC1 4040588 c.117T>C synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4040594 c.111G>T synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4040597 c.108C>T synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040600 c.105A>G synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4040603 c.102T>G synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040606 c.99T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4040618 c.87C>G synonymous_variant 0.17 pyrazinamide Uncertain significance
glpK 4138676 c.1080T>C synonymous_variant 0.14 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138679 p.Met359Val missense_variant 0.14 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138757 c.999A>G synonymous_variant 0.17 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138787 c.969C>T synonymous_variant 0.22 ethambutol Not assoc w R - Interim
isoniazid Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
rifampicin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
glpK 4138796 c.960A>G synonymous_variant 0.19 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138802 c.954G>C synonymous_variant 0.18 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138808 c.948G>T synonymous_variant 0.15 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138823 c.933G>C synonymous_variant 0.15 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138847 c.909A>C synonymous_variant 0.16 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138853 c.903C>A synonymous_variant 0.16 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138859 p.Asn299Glu missense_variant 0.16 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138875 p.Thr294Lys missense_variant 0.17 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
glpK 4138877 c.879A>G synonymous_variant 0.17 ethambutol Uncertain significance
isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
embC 4240816 c.954C>A synonymous_variant 0.15 ethambutol Uncertain significance
embC 4240819 c.957A>C synonymous_variant 0.14 ethambutol Uncertain significance
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4243460 c.228C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4248118 c.1605T>C synonymous_variant 0.15 ethambutol Uncertain significance
embB 4248130 c.1617G>C synonymous_variant 0.14 ethambutol Uncertain significance
embB 4248142 c.1629T>C synonymous_variant 0.15 ethambutol Uncertain significance
embB 4248143 p.Leu544Ile missense_variant 0.15 ethambutol Uncertain significance
embB 4248157 c.1644A>G synonymous_variant 0.16 ethambutol Not assoc w R - Interim
embB 4248158 p.Cys549Ser missense_variant 0.16 ethambutol Uncertain significance
embB 4248167 p.Thr552Ala missense_variant 0.18 ethambutol Uncertain significance
embB 4248170 p.Ala553Ser missense_variant 0.18 ethambutol Uncertain significance
embB 4248173 p.Val554Leu missense_variant 0.18 ethambutol Uncertain significance
embB 4248199 c.1686A>G synonymous_variant 0.22 ethambutol Uncertain significance
embB 4248206 p.Ser565Gly missense_variant 0.21 ethambutol Uncertain significance
embB 4248220 c.1707A>G synonymous_variant 0.19 ethambutol Not assoc w R - Interim
embB 4248225 p.Ala571Val missense_variant 0.19 ethambutol Uncertain significance
embB 4248252 p.Gly580Ala missense_variant 0.15 ethambutol Uncertain significance
aftB 4267647 p.Asp397Gly missense_variant 1.0 ethambutol Not assoc w R
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
gid 4407588 c.615A>G synonymous_variant 1.0 streptomycin Not assoc w R
gid 4407927 p.Glu92Asp missense_variant 1.0 streptomycin Not assoc w R