TB-Profiler result

Run: ERR2693254
Summary

Run ID: ERR2693254

Sample name:

Date: 2024-10-05T03:07:49.316350

Number of reads: 288747

Percentage reads mapped: 31.62

Median coverage: 12.0

Strain: La1.6;La3;lineage4.9

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.88
lineage4.9 Euro-American (H37Rv-like) None 0.92
La3 M.orygis None 0.07
La1.6 M.bovis None 0.06
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.Ala356Val Uncertain significance Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
embB 4247580 p.Ala356Val missense_variant 1.0 ethambutol Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 777 c.777A>G synonymous_variant 1.0 isoniazid
dnaA 792 c.792C>T synonymous_variant 1.0 isoniazid
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 804 c.804G>A synonymous_variant 1.0 isoniazid
dnaA 805 c.805T>C synonymous_variant 1.0 isoniazid
dnaA 813 c.813C>T synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 1.0 isoniazid
dnaA 834 c.834C>T synonymous_variant 1.0 isoniazid
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 843 c.843T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 852 c.852G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1068 c.1068T>C synonymous_variant 1.0 isoniazid
dnaA 1077 c.1077A>G synonymous_variant 1.0 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 1.0 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 1.0 isoniazid
dnaA 1122 c.1122C>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1125 c.1125G>T synonymous_variant 1.0 isoniazid
dnaA 1128 c.1128G>C synonymous_variant 1.0 isoniazid
dnaA 1149 c.1149C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1153 c.1153T>C synonymous_variant 1.0 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 1.0 isoniazid
dnaA 1164 c.1164A>T synonymous_variant 1.0 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 1.0 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 1.0 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 1.0 isoniazid
dnaA 1210 p.Ala404Ser missense_variant 1.0 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
gyrB 6100 c.861G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6103 c.864G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6121 c.882C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6209 c.970C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6229 c.990G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 6304 c.-998C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6310 c.-992G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6313 c.-989C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6316 c.-986G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6337 c.1098G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6772 c.1533C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6778 c.-524C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6805 c.1566G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6808 c.1569C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6850 c.-452C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6934 c.-368A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6943 c.-359G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6967 c.-335T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6994 c.-308C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7010 c.-292C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7021 c.-281G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7100 c.-202_-200delTTGinsCTC upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7524 c.223C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7532 c.231T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8321 c.1020C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8360 c.1059G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8391 p.Tyr364His missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8402 p.Asp367Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8438 c.1137C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8483 c.1182G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8510 c.1209G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8537 c.1236G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8555 c.1254G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8783 c.1482G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8796 p.Ile499Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8816 c.1515C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8818 p.Ser506Asn missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8954 c.1653G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8965 c.1664_1665insG frameshift_variant 1.0 levofloxacin
moxifloxacin
gyrA 8968 c.1668delG frameshift_variant 1.0 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.95 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9074 c.1773G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCTG synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9134 c.1833C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9153 p.Thr618Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9167 c.1866C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9179 c.1878C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9188 c.1887C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9191 c.1890G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9218 c.1917C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9251 c.1950G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9257 c.1956C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
fgd1 491063 p.Gly94Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491082 c.300T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491083 p.Val101Ile missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491091 c.309T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491106 c.324T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491121 c.339A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491137 p.Glu119Gln missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491144 p.Ala121Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491169 c.387C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491181 c.399T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491191 p.Gly137Arg missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491196 c.414A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491202 c.420G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491203 p.Gln141Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491212 p.Ser144Arg missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491217 c.435T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491219 p.Asp146Gly missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491226 c.444C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491229 c.447C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491232 c.450T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491244 c.462T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491259 c.477T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491283 p.Asp167Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491286 c.504G>C synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491292 c.510G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491295 c.513C>G synonymous_variant 0.91 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491302 p.Ile174Val missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491331 c.549G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491340 c.558C>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491343 c.561C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491349 c.567T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491355 c.573C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491364 c.582T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491391 c.609C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491393 p.Thr204Lys missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491397 p.Glu205Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491415 c.633A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491418 c.636A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491421 c.639A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491430 c.648T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491542 c.760T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491547 c.765A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491550 c.768T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
mshA 574731 c.-617A>G upstream_gene_variant 0.92 isoniazid
ethionamide
mshA 574739 c.-609T>C upstream_gene_variant 0.92 isoniazid
ethionamide
mshA 574742 c.-606G>A upstream_gene_variant 0.92 isoniazid
ethionamide
mshA 574763 c.-585T>C upstream_gene_variant 0.93 isoniazid Uncertain significance
ethionamide
mshA 574782 c.-566C>G upstream_gene_variant 0.92 isoniazid
ethionamide
mshA 575542 c.195C>G synonymous_variant 0.9 isoniazid
ethionamide
mshA 575560 c.213C>T synonymous_variant 0.91 isoniazid
ethionamide
mshA 575561 p.Met72Val missense_variant 0.91 isoniazid
ethionamide
mshA 575571 p.Ser75Thr missense_variant 0.92 isoniazid
ethionamide
mshA 575587 c.240C>G synonymous_variant 0.94 isoniazid
ethionamide
mshA 575590 c.243T>G synonymous_variant 0.94 isoniazid
ethionamide
mshA 575629 c.282A>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575632 c.285G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575635 c.288A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
mshA 575641 c.294A>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575647 c.300G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575649 p.Val101Glu missense_variant 1.0 isoniazid
ethionamide
mshA 575659 c.312A>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575665 c.318G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575695 c.348C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
mshA 575704 c.357T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575713 c.366G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575719 c.372C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575746 c.399C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575771 p.Val142Ser missense_variant 1.0 isoniazid
ethionamide
mshA 575779 c.432A>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575786 p.Tyr147His missense_variant 1.0 isoniazid
ethionamide
mshA 575821 c.474G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575824 c.477T>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575842 c.495G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575864 c.517T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575875 c.528C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575878 c.531A>G synonymous_variant 1.0 isoniazid
ethionamide
ccsA 620170 p.Cys94Ser missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620173 p.Val95Ile missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620187 c.297C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620198 p.Gln103Leu missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620245 c.355T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620249 p.Ser120Cys missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620256 c.366C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620257 p.Ile123Leu missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620269 p.Val127Ile missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620275 c.385C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620373 c.483C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620385 c.495G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
Rv0565c 656396 p.Ser359Gly missense_variant 1.0 ethionamide
Rv0565c 656403 c.1068C>G synonymous_variant 1.0 ethionamide
Rv0565c 656423 c.1048T>C synonymous_variant 1.0 ethionamide
Rv0565c 656447 p.Ile342Val missense_variant 1.0 ethionamide
Rv0565c 656448 c.1023T>C synonymous_variant 1.0 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 1.0 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 1.0 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 1.0 ethionamide
Rv0565c 656476 p.Lys332Ala missense_variant 1.0 ethionamide
Rv0565c 656481 c.990A>G synonymous_variant 1.0 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 1.0 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656502 c.969C>T synonymous_variant 1.0 ethionamide
Rv0565c 656511 c.960T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 657259 p.Tyr71Phe missense_variant 1.0 ethionamide
Rv0565c 657267 c.204G>C synonymous_variant 0.91 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 1.0 ethionamide
Rv0565c 657317 c.154C>T synonymous_variant 1.0 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 1.0 ethionamide
Rv0565c 657342 c.129T>C synonymous_variant 1.0 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 1.0 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 1.0 ethionamide
hadA 732094 c.165T>C synonymous_variant 1.0 isoniazid
hadA 732106 c.177T>C synonymous_variant 1.0 isoniazid
hadA 732130 c.201C>G synonymous_variant 1.0 isoniazid
hadA 732133 c.204G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732134 p.Ala69Ser missense_variant 1.0 isoniazid
hadA 732151 c.222T>C synonymous_variant 1.0 isoniazid
hadA 732154 c.225G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732164 p.Thr79Val missense_variant 1.0 isoniazid
hadA 732167 p.Ala80Thr missense_variant 1.0 isoniazid
hadA 732172 p.Glu81Asp missense_variant 1.0 isoniazid
hadA 732173 p.Ala82Gln missense_variant 1.0 isoniazid
hadA 732190 c.261A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
nusG 734421 c.168A>G synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>A synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734466 c.213G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734470 c.217_219delCTTinsTTG synonymous_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734502 c.249G>A synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734792 p.Val180Ala missense_variant 1.0 rifampicin
nusG 734800 p.Val183Ile missense_variant 1.0 rifampicin
nusG 734814 c.561G>C synonymous_variant 1.0 rifampicin
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760172 c.366G>C synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 1.0 rifampicin
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760313 c.507G>C synonymous_variant 1.0 rifampicin
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 1.0 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760454 c.648C>G synonymous_variant 1.0 rifampicin
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760514 c.708C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760817 c.1011A>G synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ala missense_variant 1.0 rifampicin
rpoB 760856 c.1050C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760862 c.1056G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760934 c.1128C>G synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 1.0 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 1.0 rifampicin
rpoB 761171 c.1365C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>G synonymous_variant 1.0 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761196 c.1390C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 1.0 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762011 c.2205G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762020 c.2214G>A synonymous_variant 1.0 rifampicin
rpoB 762023 c.2217C>T synonymous_variant 1.0 rifampicin
rpoB 762029 c.2223C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762119 c.2313C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762297 c.2491C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762380 c.-990T>G upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762490 p.Val895Ala missense_variant 1.0 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.91 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 1.0 rifampicin Uncertain significance
rpoC 762521 c.-849C>G upstream_gene_variant 1.0 rifampicin
rpoB 762785 p.Asp993Glu missense_variant 1.0 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 1.0 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 1.0 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 1.0 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763052 c.-318G>C upstream_gene_variant 1.0 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 1.0 rifampicin
rpoC 763082 c.-288C>G upstream_gene_variant 1.0 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoB 763184 c.3378C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>G upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 1.0 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763430 c.61A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 1.0 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 1.0 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763537 c.168C>G synonymous_variant 1.0 rifampicin
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763600 c.231C>G synonymous_variant 1.0 rifampicin
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763648 c.279C>A synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>A synonymous_variant 1.0 rifampicin
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763768 c.399C>G synonymous_variant 1.0 rifampicin
rpoC 763790 p.Glu141Asn missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763816 c.447C>G synonymous_variant 1.0 rifampicin
rpoC 763835 p.Ala156Met missense_variant 1.0 rifampicin
rpoC 763851 p.Ala161Gly missense_variant 1.0 rifampicin
rpoC 763855 c.486C>T synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763871 p.Gly168Thr missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>T synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763927 c.558C>G synonymous_variant 1.0 rifampicin
rpoC 763948 c.579G>C synonymous_variant 1.0 rifampicin
rpoC 763963 c.594C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>G synonymous_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 1.0 rifampicin
rpoC 764071 c.702G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764110 c.741C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 1.0 rifampicin
rpoC 764245 c.876C>G synonymous_variant 1.0 rifampicin
rpoC 764257 c.888G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764269 c.900G>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764320 c.951C>G synonymous_variant 1.0 rifampicin
rpoC 764338 c.969G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764339 c.970C>T synonymous_variant 1.0 rifampicin
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764429 c.1060C>T synonymous_variant 1.0 rifampicin
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764438 c.1069_1071delCTGinsTTA synonymous_variant 1.0 rifampicin
rpoC 764443 c.1074C>T synonymous_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>A synonymous_variant 1.0 rifampicin
rpoC 764455 c.1086G>T synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>T synonymous_variant 1.0 rifampicin
rpoC 764467 c.1098C>T synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>G synonymous_variant 0.92 rifampicin
rpoC 764536 c.1167G>C synonymous_variant 1.0 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764551 c.1182G>C synonymous_variant 1.0 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 1.0 rifampicin
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 1.0 rifampicin
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 764656 c.1287C>T synonymous_variant 1.0 rifampicin
rpoC 764695 c.1326T>C synonymous_variant 1.0 rifampicin
rpoC 764749 c.1380G>C synonymous_variant 1.0 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 1.0 rifampicin
rpoC 765034 c.1665T>C synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>T synonymous_variant 1.0 rifampicin
rpoC 765292 c.1923G>T synonymous_variant 1.0 rifampicin
rpoC 765300 p.Val644Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765307 c.1938C>T synonymous_variant 1.0 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Thr missense_variant 1.0 rifampicin
rpoC 765330 p.Ser654Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 765346 c.1977C>G synonymous_variant 1.0 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>G synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 1.0 rifampicin
rpoC 765612 p.His748Arg missense_variant 1.0 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765673 p.Asp768Glu missense_variant 1.0 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765752 p.Asp795Ser missense_variant 1.0 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765823 c.2454C>G synonymous_variant 1.0 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>G synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 1.0 rifampicin
rpoC 765985 c.2616C>T synonymous_variant 1.0 rifampicin
rpoC 765994 c.2625A>G synonymous_variant 1.0 rifampicin
rpoC 766009 c.2640G>T synonymous_variant 1.0 rifampicin
rpoC 766012 c.2643C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766027 c.2658G>T synonymous_variant 1.0 rifampicin
rpoC 766054 c.2685C>T synonymous_variant 1.0 rifampicin
rpoC 766063 c.2694C>T synonymous_variant 1.0 rifampicin
rpoC 766081 c.2712T>C synonymous_variant 1.0 rifampicin
rpoC 766084 c.2715A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766085 p.Pro906Ala missense_variant 1.0 rifampicin Not assoc w R
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766141 c.2772C>T synonymous_variant 0.92 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766148 p.Thr927Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 766168 c.2799C>G synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 1.0 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 1.0 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>C synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766504 c.3135G>C synonymous_variant 1.0 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 1.0 rifampicin
rpoC 766531 c.3162G>T synonymous_variant 1.0 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 1.0 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 1.0 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 1.0 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766627 c.3258G>C synonymous_variant 1.0 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766658 p.Arg1097Gly missense_variant 1.0 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 1.0 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>A synonymous_variant 1.0 rifampicin
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766883 p.Ser1172Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 1.0 rifampicin
rpoC 766978 c.3609C>T synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767032 c.3663G>C synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>G synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767188 c.3819G>A synonymous_variant 1.0 rifampicin
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>G synonymous_variant 0.92 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.92 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.92 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.92 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.94 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.94 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.88 streptomycin
rpsL 781820 c.261G>C synonymous_variant 0.93 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.93 streptomycin
rpsL 781835 c.276T>C synonymous_variant 0.93 streptomycin Not assoc w R - Interim
rpsL 781841 c.282C>G synonymous_variant 0.93 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.93 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.92 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.92 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.92 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.9 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.91 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.92 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800540 c.-269T>C upstream_gene_variant 0.91 linezolid
rplC 800546 c.-263T>A upstream_gene_variant 0.91 linezolid
rplC 800555 c.-254C>T upstream_gene_variant 0.91 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.93 linezolid
rplC 800576 c.-233C>T upstream_gene_variant 0.93 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.93 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.94 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.95 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.95 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 1.0 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 1.0 linezolid
rplC 800690 c.-119C>G upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.95 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.96 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.95 linezolid
rplC 800744 c.-65G>A upstream_gene_variant 0.95 linezolid
rplC 800799 c.-10_-8delGGAinsC upstream_gene_variant 0.9 linezolid
rplC 800814 c.6A>G synonymous_variant 0.91 linezolid
rplC 800844 c.36T>C synonymous_variant 0.95 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.93 linezolid
rplC 800874 c.66A>G synonymous_variant 0.93 linezolid
rplC 800877 c.69A>C synonymous_variant 0.93 linezolid
rplC 800880 c.72A>C synonymous_variant 0.93 linezolid
rplC 800889 c.81C>G synonymous_variant 0.88 linezolid
rplC 800907 c.99C>G synonymous_variant 0.87 linezolid
rplC 800916 c.108A>G synonymous_variant 0.85 linezolid
rplC 800934 c.126C>G synonymous_variant 0.85 linezolid
rplC 800937 c.129A>G synonymous_variant 0.92 linezolid
rplC 800946 c.138T>C synonymous_variant 0.92 linezolid
rplC 800949 c.141T>C synonymous_variant 0.92 linezolid
rplC 801027 c.219C>G synonymous_variant 1.0 linezolid
rplC 801137 p.Ser110Thr missense_variant 1.0 linezolid
rplC 801153 c.345G>C synonymous_variant 1.0 linezolid
rplC 801201 c.393C>T synonymous_variant 1.0 linezolid
rplC 801222 c.414T>C synonymous_variant 1.0 linezolid
rplC 801228 c.420T>C synonymous_variant 1.0 linezolid
rplC 801255 c.447C>T synonymous_variant 1.0 linezolid
rplC 801264 c.456C>T synonymous_variant 1.0 linezolid
rplC 801267 c.459A>C synonymous_variant 1.0 linezolid
rplC 801270 c.462T>C synonymous_variant 1.0 linezolid
rplC 801276 c.468G>C synonymous_variant 1.0 linezolid
rplC 801312 c.504G>C synonymous_variant 1.0 linezolid
rplC 801315 c.507G>C synonymous_variant 1.0 linezolid
rplC 801324 c.516T>C synonymous_variant 1.0 linezolid
rplC 801339 c.531T>G synonymous_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801367 p.Ala187Thr missense_variant 1.0 linezolid
fbiC 1303492 c.562T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303501 c.571C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303509 c.579G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303512 c.582T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303575 c.645G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303584 c.654C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303602 c.672A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303605 c.675C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303608 c.678G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303614 c.684C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303617 c.687C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303623 c.693C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303632 c.702T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303638 c.708A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303659 c.729T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303660 p.Val244Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303674 c.744C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303695 c.765T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303704 c.774T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303708 c.778T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303731 c.801A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303732 p.Ser268Pro missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303737 c.807G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303746 c.816T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303749 c.819G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303752 c.822A>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303789 p.Ile287Val missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303794 c.864A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303809 c.879G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303818 c.888C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303821 c.891C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303846 p.Phe306Met missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303854 c.924T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303860 c.930A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303869 c.939T>C synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303884 c.954T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303905 c.975G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303920 c.990C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303935 c.1005G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303947 c.1017T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303948 p.Gly340Arg missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303956 c.1026A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303961 p.Arg344Leu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303965 c.1035G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303969 p.Val347Ile missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303989 c.1059C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303998 c.1068T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304001 c.1071C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304004 c.1074A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304008 c.1078T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304022 c.1092T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304031 c.1101C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304058 p.Glu376Asp missense_variant 1.0 pretomanid
delamanid Uncertain significance
clofazimine
fbiC 1304064 c.1134G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304067 c.1137G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304070 c.1140C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304091 p.Asp387Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304092 p.Met388Leu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304096 p.Val389Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304115 c.1185A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304127 c.1197A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fbiC 1304133 c.1203G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304136 c.1206C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304169 c.1239T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304172 c.1242G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304184 c.1254G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304199 c.1269C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304205 c.1275C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304715 c.1785G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304724 c.1794A>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304742 c.1812T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304748 c.1818T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304778 c.1848T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304784 c.1854T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304799 c.1869G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304808 c.1878C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304811 c.1881C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304817 c.1887T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304823 c.1893C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304829 c.1899T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304853 c.1923C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304856 c.1926C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304869 c.1939C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304883 p.Glu651Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304910 c.1980G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304913 c.1983G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304916 c.1986T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304925 c.1995G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304928 c.1998T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304937 c.2007G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304940 c.2010A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304958 c.2028T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304970 c.2040G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304976 c.2046G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304983 c.2053C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304994 c.2064A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304995 c.2065T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305006 c.2076A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305015 c.2085G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305021 c.2091C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305033 c.2103T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305042 c.2112A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305045 c.2115A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305066 c.2136T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305069 c.2139G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305074 p.Ser715Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305078 c.2148A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305090 c.2160C>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305096 c.2166T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305099 c.2169T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305114 p.Asp728Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305117 c.2187T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
atpE 1461155 c.111C>G synonymous_variant 1.0 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 1.0 bedaquiline Uncertain significance
atpE 1461182 c.138A>G synonymous_variant 1.0 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 1.0 bedaquiline
atpE 1461189 c.145C>T synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472028 n.183A>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472045 n.200T>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.3 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.4 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.4 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472582 n.737G>A non_coding_transcript_exon_variant 0.38 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473981 n.324delGinsTT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474040 n.383G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474060 n.403G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474089 n.432C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475606 n.1949T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475639 n.1982C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475655 n.1998T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475883 n.2226A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.5 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.44 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.67 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.64 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.58 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1476573 n.2916A>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476577 n.2920T>G non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
inhA 1674279 c.78A>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674342 c.141T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674352 p.Thr51Ala missense_variant 1.0 isoniazid
ethionamide Uncertain significance
inhA 1674387 c.186A>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674471 c.270G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674503 p.Thr101Ser missense_variant 1.0 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 1.0 isoniazid
ethionamide
inhA 1674546 c.345T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674549 c.348G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674550 p.Ser117Ala missense_variant 1.0 isoniazid
ethionamide
inhA 1674570 c.369G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674576 c.375T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674582 c.381T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674585 c.384T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674589 p.Met130Leu missense_variant 1.0 isoniazid
ethionamide
inhA 1674624 c.423A>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674627 c.426T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674628 p.Ser143Gly missense_variant 1.0 isoniazid
ethionamide
inhA 1674654 c.453G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674660 c.459G>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674663 c.462G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674703 c.502T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674714 c.513C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674718 c.517A>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674726 c.525G>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674729 c.528G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674750 c.549T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674756 c.555T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674765 c.564C>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674771 c.570C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674777 c.576C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674792 c.591G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674801 c.600T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674846 c.645C>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674849 p.Gln216His missense_variant 1.0 isoniazid
ethionamide
inhA 1674870 c.669T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674876 c.675C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674879 c.678T>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674883 p.Ile228Leu missense_variant 1.0 isoniazid
ethionamide
rpsA 1833578 p.Val13Ile missense_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833613 c.72C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833673 c.132C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834009 c.468C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834262 c.721_723delTCGinsAGT synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1834411 c.870T>G synonymous_variant 0.95 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834432 c.891G>A synonymous_variant 0.94 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.95 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.95 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 0.95 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834606 c.1065C>G synonymous_variant 0.94 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.92 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 1.0 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 1.0 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834788 p.Ala416Gly missense_variant 1.0 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 1.0 pyrazinamide
tsnR 1853360 c.-246G>A upstream_gene_variant 1.0 linezolid
tsnR 1853361 c.-245T>C upstream_gene_variant 1.0 linezolid
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>C upstream_gene_variant 1.0 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 1.0 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 1.0 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 1.0 linezolid
tsnR 1853441 c.-165C>G upstream_gene_variant 1.0 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 1.0 linezolid
tsnR 1853447 c.-159C>A upstream_gene_variant 1.0 linezolid
tsnR 1853450 c.-156G>C upstream_gene_variant 1.0 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 1.0 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 1.0 linezolid
tsnR 1853468 c.-138C>G upstream_gene_variant 1.0 linezolid
tsnR 1853968 c.363C>T synonymous_variant 1.0 linezolid
tsnR 1853971 c.366G>C synonymous_variant 1.0 linezolid
tsnR 1853978 p.Val125Leu missense_variant 1.0 linezolid
tsnR 1854004 c.399T>C synonymous_variant 1.0 linezolid
tsnR 1854007 c.402C>G synonymous_variant 1.0 linezolid
tsnR 1854024 p.Ala140Gly missense_variant 1.0 linezolid
tsnR 1854030 p.Arg142His missense_variant 1.0 linezolid
tsnR 1854034 c.429C>T synonymous_variant 1.0 linezolid
bacA 2065005 c.-277C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
ndh 2101838 p.Ala402Val missense_variant 1.0 isoniazid Uncertain significance
delamanid
ethionamide Uncertain significance
ndh 2101858 p.Ile395Met missense_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101873 c.1170T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101888 p.Val385Leu missense_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101891 c.1152C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2101912 c.1131G>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101920 c.1123A>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101924 c.1119T>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101936 c.1107G>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101939 c.1104A>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101960 c.1083A>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101970 p.Glu358Ala missense_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101980 p.Asn355Asp missense_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101984 c.1059C>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102230 c.813G>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102247 p.Val266Ile missense_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102269 c.774C>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102287 c.756C>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102317 c.726A>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102341 c.702C>A synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102344 c.699T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102366 p.Ala226Glu missense_variant 1.0 isoniazid Uncertain significance
delamanid
ethionamide
ndh 2102377 c.666A>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102382 c.661C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
delamanid
ethionamide
ndh 2102389 c.654G>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102392 c.651C>G synonymous_variant 0.91 isoniazid
delamanid
ethionamide
ndh 2102683 c.360T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102712 p.Pro111Ser missense_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102787 c.256T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102791 c.252A>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102800 c.243T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102809 c.234G>A synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102812 c.231T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102830 c.213G>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102842 c.201A>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102857 c.186T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2102872 c.171A>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102883 c.160C>T synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102884 c.159G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2102899 c.144T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102919 c.124C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
delamanid
ethionamide Not assoc w R - Interim
ndh 2102929 c.114T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
pncA 2289961 c.-720C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289964 c.-723C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289970 c.-729C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289994 c.-753A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289997 c.-756G>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290006 c.-765T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290009 c.-768A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2290015 c.-774A>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290030 c.-791_-789delAATinsCAC upstream_gene_variant 1.0 pyrazinamide
pncA 2290034 c.-794_-793delGCinsAG upstream_gene_variant 1.0 pyrazinamide
pncA 2290042 c.-801T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290072 c.-831T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290075 c.-834C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2290084 c.-843T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290087 c.-846T>C upstream_gene_variant 1.0 pyrazinamide
kasA 2517920 c.-195G>A upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 1.0 isoniazid
kasA 2518627 c.513T>C synonymous_variant 1.0 isoniazid
kasA 2518789 c.675G>C synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>A synonymous_variant 1.0 isoniazid
kasA 2518798 c.684G>T synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518843 c.729T>G synonymous_variant 1.0 isoniazid
kasA 2518849 c.735G>C synonymous_variant 1.0 isoniazid
kasA 2518855 c.741C>G synonymous_variant 1.0 isoniazid
kasA 2518864 c.750G>C synonymous_variant 1.0 isoniazid
kasA 2518877 p.Lys255Arg missense_variant 1.0 isoniazid
kasA 2518885 c.771T>C synonymous_variant 1.0 isoniazid
kasA 2518893 p.Lys260Arg missense_variant 1.0 isoniazid
kasA 2518898 c.784T>C synonymous_variant 1.0 isoniazid
kasA 2518906 c.792A>G synonymous_variant 1.0 isoniazid
kasA 2518907 c.793T>C synonymous_variant 1.0 isoniazid
kasA 2518912 c.798G>C synonymous_variant 1.0 isoniazid
kasA 2518921 c.807T>C synonymous_variant 1.0 isoniazid
kasA 2519077 c.963G>C synonymous_variant 1.0 isoniazid
kasA 2519092 c.978C>T synonymous_variant 0.92 isoniazid
kasA 2519095 c.981C>G synonymous_variant 0.91 isoniazid
kasA 2519107 c.993T>C synonymous_variant 0.92 isoniazid
kasA 2519110 p.Asp332Glu missense_variant 0.92 isoniazid
kasA 2519112 p.Gln333Arg missense_variant 0.92 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.93 isoniazid
kasA 2519152 c.1038G>C synonymous_variant 0.94 isoniazid
kasA 2519167 c.1053T>C synonymous_variant 0.94 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 0.93 isoniazid
kasA 2519176 c.1062G>A synonymous_variant 0.93 isoniazid
kasA 2519179 c.1065G>T synonymous_variant 0.93 isoniazid
kasA 2519182 c.1068G>C synonymous_variant 0.93 isoniazid
kasA 2519191 c.1077G>A synonymous_variant 0.93 isoniazid
kasA 2519192 c.1078C>T synonymous_variant 0.93 isoniazid
kasA 2519197 c.1083G>C synonymous_variant 0.93 isoniazid
kasA 2519200 c.1086G>T synonymous_variant 0.93 isoniazid
kasA 2519203 c.1089C>G synonymous_variant 0.93 isoniazid
kasA 2519215 c.1101C>A synonymous_variant 0.94 isoniazid
kasA 2519221 c.1107G>C synonymous_variant 0.89 isoniazid
kasA 2519224 c.1110C>G synonymous_variant 0.88 isoniazid
kasA 2519239 c.1125A>C synonymous_variant 0.92 isoniazid
kasA 2519263 c.1149C>T synonymous_variant 0.9 isoniazid
ahpC 2726397 p.Ser69Gly missense_variant 1.0 isoniazid
ahpC 2726408 c.216T>C synonymous_variant 1.0 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 1.0 isoniazid
ahpC 2726651 c.459G>C synonymous_variant 1.0 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726660 c.468C>A synonymous_variant 1.0 isoniazid
ahpC 2726669 c.477T>C synonymous_variant 1.0 isoniazid
ahpC 2726681 c.489A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726687 c.495C>G synonymous_variant 1.0 isoniazid
ahpC 2726693 c.501C>G synonymous_variant 1.0 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 1.0 isoniazid
ahpC 2726699 c.507G>A synonymous_variant 1.0 isoniazid
ahpC 2726705 c.513C>T synonymous_variant 1.0 isoniazid
ahpC 2726717 c.525A>C synonymous_variant 1.0 isoniazid
folC 2746642 c.957T>C synonymous_variant 0.94 para-aminosalicylic_acid
folC 2746657 c.942T>C synonymous_variant 0.94 para-aminosalicylic_acid
folC 2746663 c.936T>C synonymous_variant 0.94 para-aminosalicylic_acid
folC 2746675 p.Ser308Ala missense_variant 0.94 para-aminosalicylic_acid
folC 2746678 c.921T>G synonymous_variant 0.94 para-aminosalicylic_acid
folC 2746684 c.915C>G synonymous_variant 0.94 para-aminosalicylic_acid
folC 2746687 p.Leu304Val missense_variant 0.94 para-aminosalicylic_acid
folC 2746691 p.Val303Ala missense_variant 0.94 para-aminosalicylic_acid
folC 2746714 c.885T>C synonymous_variant 0.94 para-aminosalicylic_acid
folC 2746728 c.871T>C synonymous_variant 0.94 para-aminosalicylic_acid
folC 2746734 p.Ile289Val missense_variant 0.94 para-aminosalicylic_acid
folC 2746744 c.855T>G synonymous_variant 0.93 para-aminosalicylic_acid
folC 2746759 c.840G>A synonymous_variant 0.92 para-aminosalicylic_acid
folC 2746765 c.834A>G synonymous_variant 0.92 para-aminosalicylic_acid
folC 2746771 c.828A>C synonymous_variant 0.92 para-aminosalicylic_acid
folC 2746777 c.822T>A synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747407 c.192T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747412 p.Ser63Gly missense_variant 1.0 para-aminosalicylic_acid
folC 2747414 p.Arg62Leu missense_variant 1.0 para-aminosalicylic_acid
folC 2747419 c.180C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747442 c.157T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747443 c.156G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747467 p.Asp44Glu missense_variant 1.0 para-aminosalicylic_acid
Rv2477c 2782426 c.1617G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782432 c.1611G>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782444 c.1599G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782475 p.Phe523Tyr missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782481 p.Lys521Arg missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2782504 c.1539G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782522 c.1521G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782531 c.1512C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782555 c.1488G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782558 p.Ile495Ser missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782567 c.1476C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782587 p.Leu486Met missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782591 c.1452T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782594 c.1449T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782597 c.1446G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782606 c.1437T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782612 c.1431T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782615 c.1428G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782621 c.1422T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782633 c.1410G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782639 c.1404A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782651 c.1392T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782656 c.1387C>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782675 c.1368G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782680 c.1363T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782684 c.1359T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782702 c.1341G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782705 c.1338G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 0.93 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.94 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783407 c.636C>G synonymous_variant 0.94 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783422 c.621T>G synonymous_variant 0.93 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783425 c.618C>G synonymous_variant 0.93 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783432 p.Ser204Ala missense_variant 0.93 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.94 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.94 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.95 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 0.95 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.94 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783557 c.486T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783563 c.480A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783569 c.474C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783659 p.Glu128Asp missense_variant 1.0 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783680 c.363G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783797 p.Asp82Gln missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783860 p.Asp61Glu missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783872 c.171G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783914 c.129T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783956 p.Tyr29Phe missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783962 c.81T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2784414 c.-372A>G upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784452 c.-410C>T upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784454 c.-412G>A upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784456 c.-414A>G upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784465 c.-423T>C upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784477 c.-435T>C upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784501 c.-459T>C upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784510 c.-470_-468delAGCinsGCG upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784516 c.-474C>T upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784519 c.-477G>C upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784528 c.-486T>C upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
pepQ 2859534 c.885A>G synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859539 c.880C>T synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859540 c.879A>T synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859546 c.873T>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859552 p.His289Gln missense_variant 1.0 bedaquiline
clofazimine
pepQ 2859574 p.Ala282Val missense_variant 1.0 bedaquiline
clofazimine
pepQ 2859667 p.Gln251Arg missense_variant 1.0 bedaquiline
clofazimine
pepQ 2859678 c.741A>G synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859747 c.672C>G synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859765 c.654G>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859778 p.Val214Ala missense_variant 1.0 bedaquiline
clofazimine
pepQ 2859781 p.Gln213Ala missense_variant 1.0 bedaquiline
clofazimine
pepQ 2859786 c.633G>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859793 p.Asp209Gly missense_variant 1.0 bedaquiline
clofazimine
pepQ 2859801 c.618G>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859825 p.Ala198Pro missense_variant 1.0 bedaquiline
clofazimine
pepQ 2859834 c.585T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
pepQ 2859852 c.567A>G synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859855 c.564G>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859864 c.555T>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859870 c.549T>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859873 c.546T>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859886 p.Ala178Val missense_variant 1.0 bedaquiline
clofazimine
pepQ 2859908 p.Gln171Glu missense_variant 1.0 bedaquiline
clofazimine
pepQ 2859909 c.510G>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859912 c.507A>G synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859918 c.501A>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859921 c.498C>G synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859924 c.495G>C synonymous_variant 1.0 bedaquiline
clofazimine
thyX 3067277 c.669C>A synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067282 p.Val222Met missense_variant 0.9 para-aminosalicylic_acid
thyX 3067284 p.Ala221Gly missense_variant 0.9 para-aminosalicylic_acid
thyX 3067304 c.642A>G synonymous_variant 0.91 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067886 c.60A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067894 c.52T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 1.0 para-aminosalicylic_acid
thyA 3074334 c.138T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074349 c.123T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074360 c.112T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074361 c.111T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074364 c.108T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074397 c.75A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074415 c.57C>G synonymous_variant 1.0 para-aminosalicylic_acid
ald 3087726 p.Ala303Ser missense_variant 0.91 cycloserine
ald 3087729 p.Ser304Ala missense_variant 0.92 cycloserine
ald 3087751 p.Tyr311Phe missense_variant 0.92 cycloserine
Rv3236c 3612694 p.Arg141Gly missense_variant 1.0 pyrazinamide Uncertain significance
Rv3236c 3612708 c.409T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612712 c.405G>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612721 c.396G>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612730 c.387C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
Rv3236c 3612736 c.381T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612757 p.Gly120Ala missense_variant 1.0 pyrazinamide
Rv3236c 3612760 c.357C>G synonymous_variant 1.0 pyrazinamide
Rv3236c 3612769 c.348T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612772 c.345T>A synonymous_variant 1.0 pyrazinamide
Rv3236c 3612786 c.331T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612787 c.330T>G synonymous_variant 1.0 pyrazinamide
Rv3236c 3612796 c.321G>C synonymous_variant 1.0 pyrazinamide
lpqB 3623411 c.1500T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623432 c.1479G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623442 p.Ser490Asn missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623444 c.1467T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623450 c.1461G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623468 c.1443T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3623480 c.1431C>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623484 p.Phe476Tyr missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623492 c.1419T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623512 p.Gly467Ser missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623532 p.Gly460Asn missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623561 c.1350T>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623570 c.1341A>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623573 c.1338T>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623576 c.1335T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623580 p.Asn444Thr missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623587 p.Ala442Pro missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623591 c.1320G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623598 p.Arg438Thr missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623602 p.Ser437Gly missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623614 p.Thr433Ala missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623615 c.1296G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623627 c.1284T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623633 c.1278G>A synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623645 c.1266G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623648 c.1263A>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623654 p.Asp419Glu missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623660 c.1251A>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623666 c.1245A>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623676 p.Val412Asn missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623682 p.Thr410Asn missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623684 c.1227T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623723 c.1188C>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623731 p.Ser394Thr missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623736 p.Ser392Thr missense_variant 1.0 rifampicin
bedaquiline
lpqB 3623739 p.His391Arg missense_variant 1.0 rifampicin Uncertain significance
bedaquiline
lpqB 3624014 c.897T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624026 c.885G>A synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624032 c.879T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624041 p.Glu290Asp missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624050 c.861C>A synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624077 c.834G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624089 c.822C>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624094 c.817A>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624100 c.811T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624101 c.810C>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624107 c.804C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624125 c.786A>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624389 c.522C>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624407 c.504C>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624416 c.495G>A synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624422 c.489G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624425 p.Glu162Ala missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624428 c.483A>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624452 c.459T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624455 c.456G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624464 c.447A>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624470 c.441T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624476 c.435C>A synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624560 c.351G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624563 c.348C>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624572 c.339C>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624575 c.336T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624594 p.Val106Ala missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624614 c.297A>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624623 c.288C>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624629 c.282G>A synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624646 c.265T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624649 c.262T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624680 c.231T>A synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624686 p.Glu75Gln missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624701 c.210T>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624707 c.204G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624722 c.189C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624728 c.183C>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624749 c.162G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624755 c.154_156delTTAinsCTG synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3625117 c.-207T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625123 c.-213T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625134 c.-224T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625135 c.1479A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625141 c.-231T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625149 p.Val489Ile missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625161 c.-251T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625162 c.1452T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625183 c.-273G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625186 c.-276T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625189 c.1425A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625195 c.-285A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625201 c.-291T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625222 c.1392T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625240 c.-330T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625243 c.-333T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625255 c.-345T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625258 c.-348G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625267 c.1347T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625270 c.-360G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625279 c.-369C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625285 c.-375G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625291 c.-381A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625294 c.-384C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625298 p.Ala439Val missense_variant 1.0 rifampicin
bedaquiline
mtrB 3625301 p.Ala438Gly missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625327 c.-417A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625345 c.-435T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625351 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625357 c.-447T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625366 c.-456C>A upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625372 c.-462A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625375 c.-465A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625381 c.-471T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625387 c.-477T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625396 c.-486G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625407 p.Gln403Glu missense_variant 1.0 rifampicin
bedaquiline
mtrB 3625408 p.Glu402His missense_variant 1.0 rifampicin
bedaquiline
mtrB 3625411 p.Ala401Glu missense_variant 1.0 rifampicin
bedaquiline
mtrB 3625419 p.Leu399Met missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625420 c.-510T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625426 c.-516G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625431 c.-521T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625438 c.-528T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625465 c.-555T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625471 c.-561C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625478 p.Asn379Ser missense_variant 1.0 rifampicin
bedaquiline
mtrB 3625480 p.Asn378Gln missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625483 c.-573C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625486 c.-576G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625489 c.-579A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625497 c.1117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625501 c.-591C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625510 c.-600T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625513 c.-603G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625528 c.-618G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625537 c.-627T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625543 c.-633G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625569 c.1045T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625579 c.-669A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625592 p.Ser341Asn missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625594 c.-684T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625602 c.-692T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625616 p.Arg333Ala missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625648 c.-738T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625675 c.-765G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625687 c.-777G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625717 c.-807C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 1.0 rifampicin Uncertain significance
bedaquiline
mtrB 3625762 c.852A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625806 c.808A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625837 c.777C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625852 c.762A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625864 c.-954T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625867 c.747A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625891 c.-981G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625909 c.-999T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625912 c.702G>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625915 c.699G>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625920 c.694C>T synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625927 c.687T>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625930 c.684C>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625942 c.672C>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625945 c.669A>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625951 c.663A>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625955 p.Leu220Ala missense_variant 1.0 rifampicin
bedaquiline
mtrB 3625967 p.Ala216Ile missense_variant 1.0 rifampicin
bedaquiline
mtrB 3625978 c.636T>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3625988 p.Thr209Gln missense_variant 1.0 rifampicin
bedaquiline
mtrB 3625999 c.615A>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626062 c.552T>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626065 c.549G>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626070 p.Ile182Val missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626077 c.537C>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626463 c.151C>T synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626987 c.-374C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626996 c.-383G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627008 c.-395G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627011 c.-398T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627059 c.-446G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627068 c.282T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627101 c.-488C>G upstream_gene_variant 0.9 rifampicin
bedaquiline
mtrB 3627104 c.-491C>G upstream_gene_variant 0.91 rifampicin
bedaquiline
mtrB 3627122 c.-509T>C upstream_gene_variant 0.92 rifampicin
bedaquiline
mtrB 3627167 c.-554T>C upstream_gene_variant 0.91 rifampicin
bedaquiline
mtrB 3627170 c.-557C>G upstream_gene_variant 0.91 rifampicin
bedaquiline
mtrB 3627173 c.-560G>C upstream_gene_variant 0.91 rifampicin
bedaquiline
mtrB 3627181 c.-568T>C upstream_gene_variant 0.91 rifampicin
bedaquiline
mtrB 3627182 c.-569T>C upstream_gene_variant 0.91 rifampicin
bedaquiline
mtrA 3627187 c.163T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627188 c.-577_-575delTTAinsCTG upstream_gene_variant 0.91 rifampicin
bedaquiline
mtrB 3627197 c.-584T>C upstream_gene_variant 0.93 rifampicin
bedaquiline
mtrB 3627203 c.-590C>G upstream_gene_variant 0.93 rifampicin
bedaquiline
mtrB 3627212 c.-599C>T upstream_gene_variant 0.93 rifampicin
bedaquiline
mtrB 3627218 c.-605G>C upstream_gene_variant 0.93 rifampicin
bedaquiline
mtrA 3627227 c.123T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627233 c.-620T>C upstream_gene_variant 0.93 rifampicin
bedaquiline
mtrB 3627236 c.-623T>G upstream_gene_variant 0.93 rifampicin
bedaquiline
fbiA 3641164 p.Ile208Val missense_variant 1.0 pretomanid
delamanid Uncertain significance
clofazimine Uncertain significance
fbiA 3641170 p.Met210Leu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3641184 c.-351T>C upstream_gene_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3641187 c.-348T>C upstream_gene_variant 1.0 pretomanid
delamanid