Run ID: SRR1169306
Sample name:
Date: 2024-03-26T16:45:26.670908
Number of reads: 241992
Percentage reads mapped: 18.12
Median coverage: 3.0
Strain: La3;lineage4.9
Spoligotype:
Drug-resistance: Other
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| La1.2.BCG | M.bovis | None | 0.1 |
| lineage4 | Euro-American | None | 0.96 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.96 |
| La3 | M.orygis | None | 0.09 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | embB | p.His312Arg | Mutation from literature | |
| pyrazinamide | ||||
| streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | fbiC | c.2401_2403delGAAinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| fbiC | 1305331 | c.2401_2403delGAAinsAC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance | Mutation from literature |
| embB | 4247448 | p.His312Arg | missense_variant | 1.0 | ethambutol | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 741 | c.741T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 750 | c.750C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 756 | c.756T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 771 | c.771A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 777 | c.777A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 786 | c.786C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 792 | c.792C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 795 | c.795A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 805 | c.805T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 813 | c.813C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 822 | c.822A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 828 | c.828T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 837 | c.837A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 840 | c.840G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 846 | c.846T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 849 | c.849A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 852 | c.852G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 876 | c.876C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 877 | c.877T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 882 | c.882C>T | synonymous_variant | 0.93 | isoniazid | |
| dnaA | 885 | c.885T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 897 | c.897A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1230 | c.1230A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1236 | c.1236C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1242 | c.1242G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1245 | c.1245G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1254 | c.1254T>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1278 | c.1278T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1290 | c.1290G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1293 | c.1293T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1302 | c.1302C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1428 | c.1428C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1431 | c.1431A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1440 | c.1440C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1441 | c.1441C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1461 | c.1461C>G | synonymous_variant | 1.0 | isoniazid | |
| gyrB | 6262 | c.1023G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6268 | c.1029C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6280 | c.1041T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6286 | c.1047T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6292 | c.1053G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6295 | c.1056A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6307 | c.1068T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6319 | c.1080G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 6355 | c.-947G>A | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6362 | c.-940T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6376 | c.-926G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6388 | c.-914T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6391 | c.1152G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6397 | c.1158G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6403 | c.-899T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6412 | c.-890G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6415 | c.-887G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6418 | c.-884C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6427 | c.-875T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6610 | c.-692C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6613 | c.-689A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6616 | c.-686A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6637 | c.-665T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6640 | c.-662A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6643 | c.-659A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6649 | c.-653T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6655 | c.-647T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6664 | c.1425C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6673 | c.-629A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6680 | c.1441C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6688 | c.-614C>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6703 | c.-599G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6706 | c.-596G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6712 | c.-590G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6727 | c.-575G>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6728 | c.1489_1491delCTAinsTG | frameshift_variant&stop_gained | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrB | 6745 | c.1506T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6775 | c.-527G>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6793 | c.1554T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6798 | p.Gly520Ala | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 6803 | c.-499C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6841 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6844 | c.-458T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6856 | c.1617T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6859 | c.1620T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6862 | c.1623C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6866 | c.-436C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6878 | c.1639T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6881 | c.1642T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6889 | c.-413G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7178 | c.-124T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7391 | c.90C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7406 | c.105G>C | synonymous_variant | 0.85 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7427 | c.126G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7433 | c.132G>T | synonymous_variant | 0.85 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7442 | c.141G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7445 | c.144C>T | synonymous_variant | 0.91 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7460 | c.159C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7508 | c.207C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7532 | c.231T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7547 | c.246C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7571 | c.270G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7577 | c.276C>T | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7592 | c.291G>C | synonymous_variant | 0.9 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7763 | c.462T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7769 | c.468C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7778 | c.477G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7784 | c.483A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7793 | c.492G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7796 | c.495G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7799 | c.498A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8090 | c.789C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8096 | c.795T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8099 | c.798T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8121 | c.820T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8135 | c.834C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8156 | c.855T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8168 | c.867A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8174 | c.873C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8177 | c.876A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8198 | c.897T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8207 | c.906T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8210 | c.909G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8219 | c.918T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8228 | c.927G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8237 | c.936A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8246 | c.945C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8247 | c.946_948delATCinsGG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8264 | c.963T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8267 | c.966G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8283 | c.982_984delATCinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8288 | c.987T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8294 | c.993T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8337 | c.1036_1038delCTAinsTG | frameshift_variant&stop_gained | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8340 | p.Ala347Ser | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8360 | c.1059G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8372 | c.1071G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8375 | c.1074G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 8382 | p.Leu361Met | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8420 | c.1119T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8423 | c.1122G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8504 | c.1203G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8561 | c.1260A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8570 | c.1269G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8576 | c.1275C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8579 | c.1278C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8585 | c.1284C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8603 | c.1302A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8624 | c.1323G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8627 | c.1326C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8636 | c.1335A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8655 | p.Ile452Val | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8660 | c.1359C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8672 | c.1371A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8693 | c.1392T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8711 | c.1410A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8714 | c.1413A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8729 | c.1428T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8730 | p.Gly477Arg | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 8740 | p.Arg480His | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8747 | c.1446A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8756 | c.1455A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8939 | c.1638T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8963 | c.1662C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8966 | c.1665C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8967 | p.Ala556Arg | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8983 | p.Cys561Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9182 | c.1881T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9191 | c.1890G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9197 | c.1896G>C | synonymous_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9200 | c.1899A>G | synonymous_variant | 0.91 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9203 | c.1902G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 9204 | p.Ser635Thr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9230 | c.1929T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9252 | p.Val651Ile | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9267 | p.Asn656Gly | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9296 | c.1995T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9308 | p.Asp669Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9315 | c.2014C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9318 | c.2017C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 9329 | c.2028C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9335 | c.2034G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| mshA | 575734 | c.387T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575737 | c.390T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575746 | c.399C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575756 | c.409C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575764 | c.417C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575771 | p.Val142Ser | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575779 | c.432A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575812 | c.465C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ccsA | 619570 | c.-321G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619574 | c.-317G>A | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619579 | c.-312G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619591 | c.-300G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619618 | c.-273C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619627 | c.-264C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619634 | c.-257T>A | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619645 | c.-246G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619654 | c.-237A>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620307 | c.417C>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620310 | c.420C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620313 | c.423G>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620317 | c.427_429delGTCinsTG | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620340 | c.450C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620343 | c.453G>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620349 | c.459A>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620362 | p.Ala158Thr | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620373 | c.483C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620385 | c.495G>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620412 | c.522T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620433 | c.543C>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620436 | c.546T>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620439 | c.549T>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620445 | c.555A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620454 | c.564C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| Rv0565c | 656481 | c.990A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656484 | c.987T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657620 | c.-150C>T | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657626 | c.-156C>T | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657632 | c.-162G>A | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657650 | c.-180G>A | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657678 | c.-208A>C | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657680 | c.-210G>A | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657686 | c.-216C>G | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657689 | c.-220_-219delCAinsAC | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 1.0 | ethionamide | |
| hadA | 731747 | c.-183T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731768 | c.-162G>A | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731774 | c.-156T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731789 | c.-141A>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731792 | c.-138G>A | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731801 | c.-129C>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731816 | c.-114G>A | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 732259 | c.330T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732270 | p.Glu114Val | missense_variant | 1.0 | isoniazid | |
| hadA | 732272 | p.Ala115Ser | missense_variant | 1.0 | isoniazid | |
| hadA | 732301 | c.372G>A | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732305 | p.Ile126Val | missense_variant | 1.0 | isoniazid | |
| hadA | 732308 | p.Val127Ile | missense_variant | 1.0 | isoniazid | |
| hadA | 732319 | c.390G>A | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732321 | p.Glu131Ala | missense_variant | 1.0 | isoniazid | |
| hadA | 732329 | p.Leu134Val | missense_variant | 1.0 | isoniazid | Uncertain significance |
| hadA | 732346 | c.417T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732370 | c.441C>T | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 1.0 | isoniazid | |
| hadA | 732389 | p.Ser154Thr | missense_variant | 1.0 | isoniazid | |
| hadA | 732396 | p.Gly156Ala | missense_variant | 1.0 | isoniazid | |
| hadA | 732398 | p.Ala157Thr | missense_variant | 1.0 | isoniazid | |
| nusG | 734421 | c.168A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734424 | c.171G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734442 | c.189G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734451 | c.198G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734454 | c.201A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734457 | c.204C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734460 | c.207G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734472 | c.219T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734502 | c.249G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734520 | c.267C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734559 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734580 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734589 | c.336G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760101 | c.295T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760112 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760118 | c.312T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760139 | c.333A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760142 | c.336C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760145 | c.339C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760154 | c.348C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760181 | c.375T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760223 | c.417T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760283 | c.477G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760307 | c.501T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760328 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760357 | p.Thr184Ser | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760370 | c.564C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760380 | p.Thr192Leu | missense_variant | 1.0 | rifampicin | |
| rpoB | 760403 | c.597C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760412 | c.606C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760415 | c.609C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760418 | c.612G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760424 | c.618C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760463 | c.657C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760478 | c.672C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760522 | p.Ser239Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760532 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760533 | p.Val243Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 760547 | c.741G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760563 | p.Arg253Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760589 | c.783C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760591 | p.Val262Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760643 | c.837G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760646 | c.840C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760655 | c.849A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760661 | c.855A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760670 | c.864G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760674 | c.868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760679 | c.873A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760683 | c.877T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760724 | c.918T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760730 | c.924T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760751 | c.945G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760769 | c.963C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760784 | c.978G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760793 | c.987A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760805 | c.999G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760811 | c.1005C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760820 | c.1014T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760826 | c.1020C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760829 | c.1023C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760830 | c.1024T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760845 | p.Thr347Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760859 | c.1053T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760862 | c.1056G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760877 | c.1071G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760886 | c.1080A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760916 | c.1110C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760919 | c.1113C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760925 | c.1119T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760931 | c.1125C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760964 | c.1158C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760982 | c.1176G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761021 | c.1215G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761057 | c.1251G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761084 | c.1278C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761132 | c.1326G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761147 | c.1341C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761189 | c.1383T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761198 | c.1392G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761258 | c.1452G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761286 | c.1480C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761289 | p.Ser495Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761292 | p.Val496Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761297 | c.1491C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761345 | c.1539G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761354 | c.1548C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761358 | c.1552_1554delGTTinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761373 | p.Val523His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761492 | c.1686G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761510 | c.1704T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761531 | c.1725C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761600 | c.1794T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761612 | c.1806G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761969 | c.2163G>A | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 762014 | c.2208C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762138 | c.2332C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762149 | c.2343G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762161 | c.2355C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762209 | c.2403C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762233 | c.2427G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762254 | c.2448T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762296 | c.2490G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762329 | c.2523G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762389 | c.-981G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762410 | c.-960T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762419 | c.-951C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762449 | c.2643C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762452 | c.2646G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762470 | c.2664G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762489 | p.Val895Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 762512 | c.-858C>G | upstream_gene_variant | 0.89 | rifampicin | |
| rpoC | 762521 | c.-849C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762527 | c.-843G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762537 | c.-833T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762551 | c.-819C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762776 | c.-594C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762785 | p.Asp993Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762788 | c.2982G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762789 | p.Leu995Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762799 | p.Ala998Gly | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762812 | c.3006C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762813 | p.Met1003Val | missense_variant | 1.0 | rifampicin | |
| rpoC | 762818 | c.-552C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762827 | c.3021G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762836 | c.3030C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762860 | c.3054G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762929 | c.3123G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762962 | c.3156C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762983 | c.-387C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762989 | c.-381G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762995 | c.3189G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763028 | c.3222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763034 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763085 | c.3279C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763136 | c.3330C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763139 | c.-231C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763148 | c.-222G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763158 | c.-212C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763166 | c.3360A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763169 | c.-201A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763178 | c.-192G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763181 | c.-189G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763202 | c.-168A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763205 | c.-165G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763208 | c.-162T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763226 | c.-144A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763238 | c.3432T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763253 | c.-117G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763402 | c.33C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763411 | c.42T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763414 | c.45T>C | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 763441 | c.72C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763495 | c.126G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763573 | c.204G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763576 | c.207C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763603 | c.234C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763615 | c.246G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763636 | c.267T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763657 | c.288G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763669 | c.300C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763675 | c.306C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763696 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763711 | c.342G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763723 | c.354G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763732 | c.363C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763741 | c.372C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763744 | c.375G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763765 | c.396T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764032 | p.Asp221Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 764040 | p.Ser224Asn | missense_variant | 1.0 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764059 | c.690G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764098 | c.729A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764101 | c.732C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764102 | p.Val245Ile | missense_variant | 1.0 | rifampicin | |
| rpoC | 764110 | c.741C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764131 | c.762T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764159 | c.790C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764195 | p.Ser276Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 764203 | c.834G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764206 | c.837T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764242 | c.873C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764257 | c.888G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764269 | c.900G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764272 | c.903G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764293 | c.924G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764320 | c.951C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764338 | c.969G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764383 | c.1014C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764405 | c.1036A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764419 | c.1050C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764428 | c.1059G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764431 | c.1062G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764452 | c.1083T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764489 | c.1120C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764500 | c.1131C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764536 | c.1167G>C | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764554 | c.1185C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764560 | c.1191T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764576 | c.1207_1208delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764593 | c.1224C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764626 | c.1257C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764668 | c.1299C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764692 | c.1323C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764746 | c.1377G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764803 | c.1434C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764827 | c.1458G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764872 | c.1503A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764932 | c.1563C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764935 | c.1566T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764959 | c.1590G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764971 | c.1602C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764995 | c.1626C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 765005 | c.1637_1638insGC | frameshift_variant | 1.0 | rifampicin | |
| rpoC | 765010 | p.Leu547Phe | missense_variant | 1.0 | rifampicin | |
| rpoC | 765011 | p.Ser548Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 765014 | c.1646_1647delCC | frameshift_variant | 1.0 | rifampicin | |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765055 | c.1686C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765073 | c.1704G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765076 | c.1707A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765079 | c.1710T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765082 | c.1713G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765085 | c.1716T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765089 | c.1720T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765103 | c.1734G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765310 | c.1941G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765319 | c.1950A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765326 | p.His653Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765330 | p.Ser654Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765352 | c.1983G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765370 | c.2001G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765371 | c.2002C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765383 | p.Met672Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765404 | p.Leu679Val | missense_variant | 1.0 | rifampicin | |
| rpoC | 765409 | c.2040T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765421 | c.2052C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765451 | c.2082C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765452 | c.2083_2085delGCCinsTG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765508 | c.2139C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765541 | c.2172C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765553 | c.2184C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765556 | c.2187G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765562 | c.2193G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765580 | c.2211G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765583 | c.2214G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765613 | p.His748Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 765625 | c.2256C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765628 | c.2259G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765631 | p.Asp754Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 765658 | c.2289C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765739 | c.2370G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765751 | c.2382C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765753 | p.Asp795Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765772 | c.2403C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765784 | c.2415C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765811 | c.2442T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765871 | c.2502T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765973 | c.2604C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766021 | c.2652G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766027 | c.2658G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766043 | p.Gln892Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766054 | c.2685C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766459 | c.3090G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766477 | c.3108G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766480 | c.3111C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766483 | c.3114G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766484 | c.3115_3117delGTAinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766495 | c.3126C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766522 | c.3153C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766528 | c.3159T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766531 | c.3162G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766543 | c.3174C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766583 | c.3214_3216delGGTinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766591 | c.3222A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766594 | c.3225G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766666 | c.3297C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766711 | c.3342C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766801 | c.3432C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766813 | c.3444G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766861 | c.3492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766894 | c.3525T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766895 | c.3526T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766903 | c.3534C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766933 | c.3564A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766972 | c.3603G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766978 | c.3609C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767062 | c.3693C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767134 | c.3765C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767167 | c.3798C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767209 | c.3840T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767212 | c.3843G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767230 | c.3861G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| mmpL5 | 775927 | c.2554C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775937 | c.2544G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775966 | p.Ala839Ser | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775981 | p.Leu834Met | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775991 | c.2490G>A | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777170 | c.1311T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777173 | c.1308C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777176 | p.Glu435Asp | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777179 | c.1302G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777188 | c.1293T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777191 | c.1290C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777194 | c.1287A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777203 | c.1278G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777206 | c.1275A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 777212 | c.1269C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| rpsL | 781595 | c.36T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781598 | c.39G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781605 | p.Ile16Val | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rpsL | 781608 | p.Ser17Ala | missense_variant | 1.0 | streptomycin | |
| rpsL | 781628 | c.69T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781649 | c.90T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781682 | c.123T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781715 | c.156T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781724 | c.165G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781733 | c.174G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781742 | c.183C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781751 | c.192G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 0.93 | streptomycin | |
| rpsL | 781763 | c.204C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781772 | c.213C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781808 | c.249C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781814 | c.255C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781817 | c.258G>A | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781820 | c.261G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781838 | c.279G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781841 | c.282C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781853 | c.294C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781859 | c.300T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781907 | c.348T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rplC | 800537 | c.-272C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800546 | c.-263T>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800567 | c.-242A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800582 | c.-227C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800591 | c.-218C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800594 | c.-215C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800600 | c.-209G>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800648 | c.-161A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800654 | c.-155T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800690 | c.-119C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800693 | c.-116A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800703 | c.-106T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800720 | c.-89T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800723 | c.-86C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800738 | c.-71T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800747 | c.-62C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800771 | c.-38C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800829 | c.21C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800844 | c.36T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800856 | c.48A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801195 | c.387G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801246 | c.438C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801249 | c.441T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801255 | c.447C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801367 | p.Ala187Thr | missense_variant | 1.0 | linezolid | |
| fbiC | 1303509 | c.579G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303521 | c.591C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303785 | c.855G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303788 | c.858T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303789 | p.Ile287Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303812 | c.882C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303821 | c.891C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303845 | c.915C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303846 | p.Phe306Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303854 | c.924T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303857 | c.927C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303860 | c.930A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304796 | c.1866G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304808 | c.1878C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304811 | c.1881C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304817 | c.1887T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304829 | c.1899T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304832 | c.1902C>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304853 | c.1923C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304856 | c.1926C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304883 | c.1953G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304893 | p.Gly655Ser | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304958 | c.2028T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305135 | c.2205C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305150 | c.2220C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305177 | c.2247A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305300 | c.2370A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305303 | c.2373T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305306 | c.2376A>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305336 | c.2406T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305348 | c.2418C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305349 | c.2419C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305396 | c.2466C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305405 | c.2475A>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305417 | c.2487C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| sigE | 1365033 | c.621G>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365042 | c.630G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365063 | c.651A>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365072 | c.660G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365075 | c.663G>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365081 | c.669G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365084 | c.672G>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365090 | c.678T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365096 | c.684G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365099 | c.687A>C | synonymous_variant | 1.0 | pyrazinamide | |
| atpE | 1460816 | c.-229T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460831 | c.-214T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460840 | c.-205A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460852 | c.-193C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460855 | c.-190T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460858 | c.-187C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460882 | c.-163T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460894 | c.-151A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1461149 | c.105T>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461150 | p.Ile36Val | missense_variant | 1.0 | bedaquiline | |
| atpE | 1461159 | p.Val39Ile | missense_variant | 1.0 | bedaquiline | Uncertain significance |
| atpE | 1461170 | c.126A>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461185 | c.141G>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461189 | c.145C>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461194 | c.150C>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461197 | c.153A>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461219 | c.175T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461233 | c.189A>C | synonymous_variant | 1.0 | bedaquiline | |
| rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | ||||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 0.95 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.95 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472028 | n.183A>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472029 | n.184C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472030 | n.185G>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472031 | n.186G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472044 | n.199G>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473813 | n.156C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473839 | n.182G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473899 | n.242A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473944 | n.287G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473971 | n.314G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473981 | n.324_325insT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Not assoc w R | |||||
| rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474036 | n.379G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474040 | n.383G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474054 | n.397T>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474061 | n.404T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474093 | n.436G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474099 | n.442G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474110 | n.453A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474291 | n.634_649delTTTCCTCTCCGGAGGAinsC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474904 | n.1247G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474956 | n.1299C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474961 | n.1304T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474963 | n.1306G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474964 | n.1307T>C | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
| linezolid | ||||||
| rrl | 1474970 | n.1313G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475006 | n.1349A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475013 | n.1356G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475201 | n.1544G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475206 | n.1549C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475209 | n.1552G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475249 | n.1592T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475252 | n.1595C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475266 | n.1609T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475267 | n.1610G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475275 | n.1618C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475276 | n.1619T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475313 | n.1656G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475333 | n.1676T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475369 | n.1712G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475401 | n.1745delC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475405 | n.1748A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | Uncertain significance | |||||
| rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475638 | n.1981C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
| linezolid | ||||||
| rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475761 | n.2104_2106delCGCinsGT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.91 | capreomycin | |
| linezolid | ||||||
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476025 | n.2368G>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
| linezolid | ||||||
| rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476048 | n.2391G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
| linezolid | ||||||
| rrl | 1476095 | n.2438C>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
| linezolid | ||||||
| rrl | 1476105 | n.2448_2449delGAinsT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476117 | n.2460G>C | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
| linezolid | ||||||
| rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476297 | n.2640C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476299 | n.2642C>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476746 | n.3089T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476750 | n.3093T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| inhA | 1673541 | c.-661G>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| inhA | 1673547 | c.-655T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673574 | c.-628C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673580 | c.-622T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| inhA | 1673589 | c.-613A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673592 | c.-610G>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673595 | c.-607A>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673596 | p.Lys53Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673607 | c.-595T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673609 | p.Gly57Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673616 | c.-586A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673633 | p.Ser65Asn | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673646 | c.-556T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673657 | p.Thr73Lys | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673660 | p.Ala74Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673664 | c.-538A>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673667 | c.-535A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673682 | c.-520G>C | upstream_gene_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| fabG1 | 1673710 | p.Leu91Ile | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673716 | p.Ala93Lys | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673724 | c.-478A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673733 | p.Met98Ile | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674501 | c.300G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674507 | c.306G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674537 | c.336C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674540 | c.339C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674542 | p.Ala114Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674549 | c.348G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674555 | c.354G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674561 | c.360C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674573 | c.372G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674582 | c.381T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674585 | c.384T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674589 | p.Met130Leu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674601 | p.Leu134Thr | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674624 | c.423A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674627 | c.426T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674636 | c.435C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674654 | c.453G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674660 | c.459G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674669 | c.468G>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674672 | c.471C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674813 | c.612C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674828 | c.627G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674840 | c.639C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674846 | p.Ile215Met | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674849 | c.648G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674858 | c.657G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674870 | c.669T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674873 | c.672G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674879 | c.678T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674903 | c.702T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674904 | p.Ala235Pro | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674934 | c.733C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674939 | c.738G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674942 | c.741T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833517 | c.-24delC | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833554 | p.Thr5Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1833589 | c.48A>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833595 | c.54T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833604 | c.63C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833667 | c.126C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833703 | c.162C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833721 | c.180A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833742 | c.201A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833745 | c.204G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833760 | c.219C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833772 | c.231C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833782 | p.Ser81Thr | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833793 | c.252C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833811 | c.270G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833838 | c.297G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833844 | c.303C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833940 | c.399C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833971 | c.430C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833991 | c.450C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834030 | c.489C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834051 | c.510G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834097 | c.556_557delTCinsAG | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834102 | c.561T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834210 | c.669C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834213 | c.672G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834222 | c.681T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834252 | c.711C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834264 | c.723G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834297 | c.756C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834303 | c.762T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834315 | c.774C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834333 | c.792C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834369 | c.828C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834375 | c.834G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834396 | c.855G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834417 | c.876G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834423 | c.882G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834435 | c.894G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834474 | c.933C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834477 | c.936C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834495 | c.954G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834498 | c.957C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834528 | c.987T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834540 | c.999G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834570 | c.1029C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834606 | c.1065C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834705 | c.1164C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834738 | c.1197A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834753 | c.1212T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834756 | c.1215G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834765 | c.1224A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834780 | c.1239A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834786 | c.1245A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834789 | c.1248T>C | synonymous_variant | 1.0 | pyrazinamide | |
| tsnR | 1853375 | c.-231G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 1.0 | linezolid | |
| bacA | 2063588 | c.1141T>C | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2063610 | c.1117_1119delTCCinsGA | frameshift_variant&stop_gained | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| bacA | 2063613 | c.1116T>G | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2063625 | c.1104G>T | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2063628 | c.1101C>G | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2063640 | c.1089C>T | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2063648 | p.Gln361Lys | missense_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| bacA | 2063649 | c.1080G>C | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2063658 | c.1069_1071delTTAinsCG | frameshift_variant&missense_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| bacA | 2063664 | c.1065T>G | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| kanamycin | Not assoc w R - Interim | |||||
| capreomycin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| bacA | 2063673 | c.1056C>T | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| pncA | 2290009 | c.-768A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290015 | c.-774A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| kasA | 2517926 | c.-189G>A | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517956 | c.-159G>A | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517965 | c.-150C>T | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517974 | c.-141T>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517989 | c.-126T>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517993 | c.-122G>T | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518146 | p.Phe11Tyr | missense_variant | 1.0 | isoniazid | |
| kasA | 2518162 | c.48G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518174 | c.60A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518183 | c.69G>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518190 | p.Ser26Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518220 | c.106C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518234 | c.120G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518714 | c.600A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518732 | c.618C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518768 | c.654C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518777 | c.663C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518789 | c.675G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518792 | c.678C>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518795 | c.681C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518834 | c.720C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518843 | c.729T>G | synonymous_variant | 1.0 | isoniazid | |
| Rv2477c | 2782957 | c.1086A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783077 | c.966T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783092 | c.951A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783095 | c.948C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783098 | c.945C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783101 | c.942G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783116 | c.927T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783140 | c.903C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783149 | c.894G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783158 | c.885A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783182 | c.861C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783194 | c.849A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783203 | c.840C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783224 | c.819C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783230 | c.813T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783254 | c.789A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783263 | c.780G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783275 | c.768C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783278 | c.765A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783287 | c.756C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783293 | p.Glu250Asp | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783299 | c.744A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783302 | c.741A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783311 | c.732T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783332 | c.711T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783374 | c.669G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783395 | c.648T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783410 | c.633G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783422 | c.621T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783446 | c.597A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783461 | c.582T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783464 | c.579A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783467 | c.576G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783473 | c.570A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783499 | c.544T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783512 | c.531A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783520 | c.523T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783527 | c.516A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783605 | c.438T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783611 | c.432C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783620 | c.423C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783629 | c.414C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783656 | c.387G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783659 | c.384A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783665 | c.378A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783674 | c.369T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783683 | c.360A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783691 | c.352C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783719 | c.324A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783746 | c.297G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783751 | p.Ile98Val | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783761 | c.282G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783766 | p.Met93Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783770 | c.273G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783776 | c.267G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783779 | c.264T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783815 | c.228A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783883 | c.160T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783884 | c.159T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783887 | c.156C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783914 | c.129T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783920 | c.123G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783929 | c.114C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783932 | c.111C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783953 | c.90G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783962 | c.81T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783971 | c.72G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783980 | c.63C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783992 | c.51T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2752c | 3064958 | p.Ser412Arg | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3064962 | c.1230C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064973 | p.Ala407Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064974 | c.1218T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064995 | c.1197C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064998 | c.1194A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065007 | c.1185G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065013 | c.1179G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065466 | c.726G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065475 | c.717C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065532 | c.660A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065553 | c.639A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065562 | c.630T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066024 | c.168T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066040 | p.Gly51Thr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066042 | c.150T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066050 | p.Leu48Met | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066054 | c.138T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066066 | c.126T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066071 | c.121T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066075 | c.117A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066096 | c.96G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066452 | c.-261T>A | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066459 | c.-268T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066465 | c.-274G>A | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066471 | c.-280A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066476 | c.-285C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066480 | c.-291_-289delGCCinsTT | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066501 | c.-310G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066531 | c.-340C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066543 | c.-352C>A | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066549 | c.-358T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066556 | c.-365C>T | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066561 | c.-370A>T | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066567 | c.-376C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066573 | c.-382G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066579 | c.-388A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066583 | c.-392C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066804 | c.-613G>T | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066807 | c.-616T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| thyX | 3067277 | c.669C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067284 | p.Ala221Gly | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067289 | c.657C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067316 | c.630A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067355 | c.591A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067367 | c.579G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067373 | c.573C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067382 | c.564C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067388 | c.558C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067661 | c.285C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067667 | c.279G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067694 | c.252G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067706 | c.240C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067715 | c.231C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067718 | c.228C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067721 | c.225T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067724 | c.222G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067727 | c.219A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067739 | c.207T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067742 | c.204A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067760 | c.184_186delCGGinsAC | frameshift_variant&missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067765 | p.Leu61Ile | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067781 | c.165C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067787 | p.Lys53Arg | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067799 | c.147G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067802 | c.144C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067849 | p.Pro33Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067850 | c.96A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067869 | p.Thr26Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067874 | c.72C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067883 | c.63C>G | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyX | 3067886 | c.60A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067889 | c.57C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073920 | c.552C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073926 | c.546G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073929 | c.543T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073953 | c.519T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073977 | c.495A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073983 | c.489C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073989 | c.483T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074004 | c.468T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074022 | c.450C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074031 | c.441T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| lpqB | 3624680 | c.231T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624683 | c.228G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624686 | c.223_225delGAAinsCG | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3624701 | c.210T>C | synonymous_variant | 0.92 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624704 | c.207G>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624707 | c.204G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624728 | c.183C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624731 | c.180C>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624749 | c.162G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624755 | c.154_156delTTAinsCG | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3625255 | c.-345T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625267 | c.1347T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625279 | c.-369C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625282 | c.1332C>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625291 | c.-381A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625313 | p.Arg434Lys | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625315 | c.-405G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625321 | c.1293A>G | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625327 | c.-417A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625333 | c.-423C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625345 | c.-435T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625588 | c.-678G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625592 | p.Ser341Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625616 | p.Arg333Ala | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625621 | c.-711G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625630 | c.-720C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625656 | c.958T>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625672 | c.-762G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625705 | c.909C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625711 | c.903C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625720 | c.894G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625732 | c.882C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625755 | p.Ala287Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3625762 | c.-852A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625765 | c.849C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625774 | c.840G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625806 | c.808A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625852 | c.762A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625855 | c.759G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625876 | c.738G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625888 | c.726G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625909 | c.-999T>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625927 | c.687T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625930 | c.684C>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625936 | c.678C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626735 | c.-122C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626746 | c.-133C>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626774 | c.574_576delAGGinsCC | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626786 | c.564A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626792 | c.558G>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626804 | c.546A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626846 | c.504G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 0.9 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626869 | c.481C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626885 | c.-272A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626891 | c.-278G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626894 | c.-281C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626912 | c.-299T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626939 | c.411A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627065 | c.-452G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627068 | c.282T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627074 | c.-461G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627080 | c.270T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627098 | c.252A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627119 | c.231T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627128 | c.-515T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627137 | c.213G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627167 | c.-554T>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627188 | c.162A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627194 | c.154_156delCTGinsTA | frameshift_variant&synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627208 | c.142C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627221 | c.129C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627227 | c.123T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627242 | c.108C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627275 | c.-662G>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627299 | c.49_51delTTGinsCA | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627314 | c.-701C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627342 | p.Thr3Phe | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627345 | p.Asp2Val | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| fbiB | 3642581 | c.1047A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642593 | c.1059G>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642602 | c.1068A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642605 | c.1071A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642609 | c.1075_1076delAGinsTC | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642623 | c.1089C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642662 | c.1128C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642668 | c.1134A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642677 | c.1143A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642680 | c.1146A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642684 | c.1150T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642701 | c.1167C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642711 | p.Leu393Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642716 | c.1182C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642719 | c.1185T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642740 | c.1206C>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642743 | c.1209T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642749 | c.1215T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642758 | c.1224C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| rpoA | 3877494 | p.Glu338Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3877503 | c.1005G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877506 | p.Gly334Ala | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877513 | p.Thr332Asn | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877515 | c.993G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877542 | c.966C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877553 | p.Glu319Gln | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877587 | c.921A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877613 | p.Ile299Val | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877656 | c.852T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877668 | c.840A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877677 | p.Ala277Ser | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877680 | c.828G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877692 | c.816G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877746 | c.762G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877752 | c.756C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877770 | c.738A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877818 | c.690A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877829 | p.Val227Ile | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877839 | c.669G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877854 | c.654G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877866 | c.642G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877872 | c.636C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877875 | c.633T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877896 | c.612G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877900 | p.Ser203Asn | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877905 | c.603A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877908 | p.Asn200Ser | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877920 | c.588G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877962 | c.546G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877983 | c.525C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877986 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878022 | c.486T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878025 | c.483C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878028 | c.480G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878031 | c.477T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878040 | c.468T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878052 | c.456C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878055 | c.453A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878061 | c.447G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878067 | c.441C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878070 | c.438T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878076 | c.432C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878094 | c.414C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878141 | p.Met123Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878143 | p.Gly122Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878163 | c.345C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878166 | c.342C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878169 | c.339G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878184 | c.324C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878187 | c.321C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878292 | c.216T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878298 | c.210A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878304 | c.204G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878307 | c.201C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878313 | c.195G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878331 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878334 | c.174T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878337 | c.171T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878364 | c.144A>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878367 | c.141C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878376 | c.132G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878385 | c.123C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878391 | c.117T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878415 | c.93C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878436 | c.72A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878442 | c.66G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878785 | c.-278T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878836 | c.-331_-329delAAGinsGGT | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878909 | c.-402A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878917 | c.-410G>A | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878935 | c.-428C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878938 | c.-431T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878962 | c.-455G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3879004 | c.-499_-497delAAGinsCGC | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879016 | c.-509A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879019 | c.-512T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879022 | c.-515G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879033 | c.-526C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879040 | c.-535_-533delGTGinsTCC | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879050 | c.-543A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879070 | c.-563G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879097 | c.-590C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879124 | c.-617G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879136 | c.-629A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879190 | c.-683C>G | upstream_gene_variant | 0.92 | rifampicin | |
| clpC1 | 4038433 | c.2272C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038434 | c.2271G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038440 | c.2265C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038444 | p.Ala754Lys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038446 | c.2259T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038456 | p.Val750Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038458 | c.2247G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038461 | c.2244G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038498 | p.Ser736Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038530 | p.Glu725Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038533 | p.Arg724Lys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038640 | p.Asp689Asn | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038653 | c.2052C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038658 | p.Lys683Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038661 | p.Ser682Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038662 | c.2043T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038683 | c.2022T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038692 | c.2013C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038695 | c.2010C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038701 | c.2004G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038707 | c.1998C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038740 | c.1965G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038755 | c.1950G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038782 | c.1923G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038790 | c.1915C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038815 | c.1890G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038869 | c.1836G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038890 | c.1815G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038917 | c.1788C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038923 | c.1780_1782delCTAinsTG | frameshift_variant&synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039046 | c.1659C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039064 | c.1641C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039070 | c.1635G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039103 | c.1602T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039112 | c.1593C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039128 | p.Lys526Arg | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039133 | c.1572C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039158 | p.Lys516Arg | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039169 | p.Glu512Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039172 | c.1533A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039178 | c.1527G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039268 | c.1437C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039274 | c.1431G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039283 | c.1422C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039286 | c.1419T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039556 | c.1149G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039559 | c.1146C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039574 | p.Ala377Gly | missense_variant | 0.91 | pyrazinamide | |
| clpC1 | 4039577 | c.1128T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039610 | c.1095G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039613 | c.1092C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039616 | c.1089G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039622 | c.1083C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039661 | c.1044T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039706 | c.999G>A | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039913 | c.792C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039946 | c.759A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039955 | c.750G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039958 | c.747G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039979 | c.726C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039982 | c.723G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039985 | c.720G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039991 | c.714G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039996 | p.Glu237Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040009 | c.696C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040042 | c.663C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040048 | c.657C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040105 | c.600C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040147 | c.558A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040153 | c.552A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040162 | c.543G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040165 | c.540G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040171 | c.534C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040200 | c.505T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040201 | c.504C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040207 | c.498T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040213 | c.492T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040225 | c.480A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040228 | c.477G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040237 | c.468C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040258 | c.447G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040267 | c.438A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040273 | c.432T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040277 | c.427_428delTCinsAG | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040314 | c.391C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040330 | c.375C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040462 | c.243C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040465 | c.240T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040477 | c.228G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040480 | c.225T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040486 | c.219G>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044204 | c.78G>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4045022 | c.-741C>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045028 | c.-747C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045055 | c.-774T>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| glpK | 4138564 | c.1192C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138574 | c.1182G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138606 | c.1150T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138607 | c.1149G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138615 | p.Ile381Val | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138622 | c.1134C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138631 | c.1125C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138634 | c.1122G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139600 | c.156G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139603 | c.153C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139608 | p.Leu50Met | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139611 | p.Ile49Val | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139615 | c.141G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4139627 | c.129G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4139630 | c.126C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139636 | c.120C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4139642 | c.114G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139651 | p.His35Gln | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| embC | 4240671 | p.Thr270Ile | missense_variant | 1.0 | ethambutol | Not assoc w R |
| embC | 4240678 | c.816T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240685 | p.Thr275Ala | missense_variant | 1.0 | ethambutol | |
| embC | 4240693 | c.831T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240699 | c.837C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240703 | c.841C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240726 | c.864G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240780 | c.918T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240783 | c.921G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240789 | c.927T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240819 | c.957A>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240822 | c.960C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240831 | c.969T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240861 | c.999G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240867 | c.1005T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240879 | c.1017G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240880 | p.Ala340Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4240886 | p.Ile342Val | missense_variant | 1.0 | ethambutol | |
| embC | 4240897 | c.1035C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
| embC | 4240898 | c.1036_1038delCTAinsTG | frameshift_variant&stop_gained | 1.0 | ethambutol | |
| embC | 4240911 | p.Ala350Val | missense_variant | 1.0 | ethambutol | |
| embC | 4240921 | c.1059C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240924 | c.1062C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240936 | c.1074A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240966 | c.1104G>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240969 | c.1107C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240978 | c.1116G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240979 | p.Thr373Gln | missense_variant | 1.0 | ethambutol | |
| embC | 4240983 | p.Ser374Asn | missense_variant | 1.0 | ethambutol | |
| embC | 4240990 | c.1128A>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240996 | c.1134G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241002 | c.1140G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241017 | c.1155T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241023 | c.1161T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241050 | c.1188T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241053 | c.1191G>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241065 | c.1203C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241071 | c.1209C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241104 | c.1242G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241107 | c.1245G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241140 | c.1278A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241161 | c.1299C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241162 | c.1300T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241167 | c.1305C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241179 | c.1317G>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241185 | c.1323G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241188 | c.1326C>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241989 | c.2127A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241995 | c.2133C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242002 | p.Leu714Val | missense_variant | 1.0 | ethambutol | |
| embC | 4242011 | c.2149_2151delCTTinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embC | 4242024 | p.Val721Ala | missense_variant | 1.0 | ethambutol | |
| embC | 4242036 | p.Gln725Leu | missense_variant | 1.0 | ethambutol | |
| embC | 4242045 | p.Ile728Thr | missense_variant | 1.0 | ethambutol | |
| embC | 4242047 | c.2185_2187delTCCinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embC | 4242070 | c.2208T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242073 | c.2211C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4242079 | c.2217T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242085 | c.2223A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245093 | p.Ile621Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4245101 | c.1869G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245137 | c.1905T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245149 | c.1917C>G | synonymous_variant | 0.91 | ethambutol | |
| embA | 4245164 | c.1932C>T | synonymous_variant | 0.92 | ethambutol | |
| embA | 4245173 | c.1941G>C | synonymous_variant | 0.85 | ethambutol | |
| embA | 4245182 | c.1950T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245183 | c.1951C>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245189 | c.1957C>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245198 | p.Leu656Ile | missense_variant | 1.0 | ethambutol | |
| embB | 4247437 | c.924A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247464 | c.951C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247470 | c.957T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247491 | c.978G>C | synonymous_variant | 1.0 | ethambutol |